23 Matching Annotations
  1. Apr 2026
    1. Urgent treatment for neoplasm consists of (1) cautious use of intravenous diuretics and (2) mediastinal irradiation, starting within 24 hours, with a treatment plan designed to give a high daily dose of radiation but a short total course of therapy to rapidly shrink the local tumor. Intensive radiation therapy combined with chemotherapy will palliate the process in up to 90% of patients. In patients with a subacute presentation, radiation therapy alone usually suffices. Chemotherapy is added if lymphoma or small-cell carcinoma is diagnosed

      endovascular stenting emerging as first-line therapy for rapid symptom relief, while definitive treatment targets the underlying cause

      Glucocorticoids (dexamethasone 4 mg every 6 hours) are commonly prescribed but lack robust supporting data; they may be more beneficial in lymphoma or thymoma and as prophylaxis against radiation-induced edema. [2-4] Importantly, SVC syndrome is no longer considered a medical emergency except in rare cases with life-threatening cerebral edema, laryngeal edema, or altered mental status. When thrombosis is present, catheter-directed thrombolysis or aspiration thrombectomy should be performed within 2-5 days of symptom onset before thrombus organization occurs. [3] The role of long-term anticoagulation after stenting remains unclear, though it is standard when significant thrombosis is present The American College of Chest Physicians recommends obtaining histologic diagnosis before treatment in suspected lung cancer cases, as stenting does not interfere with tissue diagnosis. [2] For small cell lung cancer (SCLC), chemotherapy alone is recommended as first-line treatment given rapid response rates. [2] For non-small cell lung cancer (NSCLC), radiation therapy and/or stent insertion are recommended, with response rates of 59% for chemotherapy and 63% for radiation therapy. [2] Patients with chemotherapy- or radiation-refractory disease should receive vascular stents For device-related thrombosis (catheters, pacemakers), catheter removal should be considered in conjunction with anticoagulation. [4] Endovascular therapy is first-line for device-related obstruction, while surgical bypass may be preferred for mediastinal fibrosis. [7] Both approaches show good mid-term patency, though secondary interventions are common (approximately 27-28%

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  2. Aug 2024
  3. Mar 2024
  4. Mar 2023
    1. Because they follow this specification, most authoritative DNS servers won't allow you to include CNAME records at the root. At CloudFlare, we decided to let our users include a CNAME at the root even though we knew it violated the DNS specification. And that worked, most of the time. Unfortunately, there were a handful of edge cases that caused all sorts of problems.
  5. May 2022
  6. Aug 2021
    1. What seems more problematic is divergence between drivers. For example, capybara-webkit and poltergeist support several of the same things. Let's take resizing the window as an example. In capybara-webkit this is page.driver.resize_window(x, y) and in poltergeist it's page.driver.resize(x, y). This means that if a user wants to switch from one to the other they have to change their code. Now I don't know if selenium does or doesn't support resizing the window, but supposing it doesn't I think there's still a lot of value in the capybara project deciding what the blessed API is, because then all the drivers that support that feature can implement it using the same API, increasing portability.
  7. Jun 2021
    1. KV is used in 8 of the overlay locales at the moment (CS, DE, HI, JA, PL, PT, SK, and CN). I don't agree with this and believe that Carmen should only reflect country codes that are part of the actual ISO standard.
  8. Apr 2021
    1. The main difference is in the flow of how messages are ultimately sent to devices for output. The standard library Logger logic converts the log entries to strings and then sends the string to the device to be written to a stream. Lumberjack, on the other hand, sends structured data in the form of a Lumberjack::LogEntry to the device and lets the device worry about how to format it. The reason for this flip is to better support structured data logging. Devices (even ones that write to streams) can format the entire payload including non-string objects and tags however they need to.
  9. Mar 2021
  10. Feb 2021
    1. Programming to an interface means that when you are presented with some programming interface (be it a class library, a set of functions, a network protocol or anything else) that you keep to using only things guaranteed by the interface. You may have knowledge about the underlying implementation (you may have written it), but you should not ever use that knowledge.
  11. Oct 2020
  12. react-spectrum.adobe.com react-spectrum.adobe.com
  13. Aug 2020
  14. Apr 2020
  15. Nov 2019