23 Matching Annotations
  1. Last 7 days
    1. Autoantibodies (AABs) have been identified in advanced Covid, laboratory models of Covid-19 utilizing S-protein fragments. The concept that addressing the AABs is a therapeutic target is reasonable, but falls short of addressing the host-targets, the ubiquitous and critical neuroreceptors that have been rendered dysfunctional by these AABs. The a7 nicotinic acetylcholine receptors (a7Rs) rendered dysfunctional are no longer capable of stabilizing the cholinergic anti-inflammatory pathway. In our clinical experience, supported with laboratory collaborations, re-establishing a7R function plays a significant role in both acute COVID-19 as well as Post-Acute Sequelae of Covid. Focusing on therapeutics for Abs 1 or Abs2 appears to be just as short-sighted for PASC as it was for using Monoclonal Abs, IL-6 inhibitors, antivirals for acute COVID-19. The focus should be entirely on the host - targets, the a7Rs and enabling the host's CAP. Ref: doi: 10.1016/biocel.2024.106519

  2. Apr 2026
    1. 金融業界へのAIの影響... 全78ページのレポート(本文は29ページ+参考文献+付録)

      「日本金融业 AI 影响」主题输出 78 页报告(正文 29 页 + 参考文献 + 附录),涵盖国内金融机构数字投资 3 万亿日元规模等具体数据。令人注意的是样本报告的选题策略:两个示例都是「高价值 B2B 决策场景」(特朗普政策风险 + 金融 AI 转型),精准对准了 Sakana 的目标客户——战略规划部门、咨询公司、智库。这是一份经过深思熟虑的产品 demo 选题,每一页都在向潜在企业客户证明「这就是我们需要的」。

  3. Mar 2026
  4. Jul 2021
  5. May 2021
  6. Mar 2021
    1. Deepti Gurdasani. (2021, February 27). The campaign against @DrZoeHyde that has involved several scientists targeting her with personal attacks, and trying to misrepresent her is deeply disappointing. She has been referred to as ‘evil’, ‘idiotic’, ‘sadistic’, and a’sociopath’. A few thoughts on these attacks. [Tweet]. @dgurdasani1. https://twitter.com/dgurdasani1/status/1365641557404229638

  7. Nov 2020
    1. Microbundle also outputs a modern bundle specially designed to work in all modern browsers. This bundle preserves most modern JS features when compiling your code, but ensures the result runs in 90% of web browsers without needing to be transpiled. Specifically, it uses preset-modules to target the set of browsers that support <script type="module"> - that allows syntax like async/await, tagged templates, arrow functions, destructured and rest parameters, etc. The result is generally smaller and faster to execute than the esm bundle
  8. Oct 2020
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  11. Mar 2020
    1. Now, if you intend to serve personalized ads to users, you’ll need to ensure that explicit consent to ad personalisation is collected before you can display personalised ads for end-users (where this consent is not collected, Google will default to serving non-personalized ads, potentially impacting your ad revenue).
    1. Google uses cookies like NID and SID to help customize ads on Google properties, like Google Search. For example, we use such cookies to remember your most recent searches, your previous interactions with an advertiser’s ads or search results, and your visits to an advertiser’s website. This helps us to show you customized ads on Google.
    1. The problem is that even if the visitor is not watching the video or interacting with it, in any capacity, YouTube still collects and stores data on them. Not cool.This is done using cookies that are placed on the user’s browser the moment they load a webpage with a YouTube video embedded in it. These cookies are used to track users, serve targeted ads (Google’s bread and butter), and add info to user’s profile. Yes, they have profiles on everyone.
    1. It wouldn’t mean an end to being able to target ads online. Contextual targeting doesn’t require personal data — and has been used successfully by the likes of non-tracking search engine DuckDuckGo for years (and profitably so). It would just mean an end to the really creepy, stalkerish stuff. The stuff consumers hate — which also serves up horribly damaging societal effects, given that the mass profiling of internet users enables push-button discrimination and exploitation of the vulnerable at vast scale.
  12. Jul 2018
  13. Jun 2017
    1. This is one of the smartest computer scientists in the world. He is not going to splash $15m on bullshit.”

      Cadwalladr starts with a bold statement: "a Hijacked Democracy." But does Micro Targeting actually work? One of the most important questions in the CA-debate. This article does not provide new facts about the impact of CA's "special sauce".

      Arguments given:

      Argument 1 by David, ex-CA:

      He is a smart guy.

      Ok, but why is the smart guy confinced?

      Argument 2 by Tamsin Shaw:

      “The capacity for this science to be used to manipulate emotions is very well established." The arguments are not given in this article. See note from aaronslodounik below for source.

      I find this a more convincing arguments about the impact here: https://civichall.org/civicist/will-the-real-psychometric-targeters-please-stand-up/

      Also Sue Halpern notes a similar overestimation of the impact of CA's "sercret sause" in this article How He Used Facebook to Win:

      After the initial alarm that an obscure data firm might have wormed its way into the American psyche deeply enough to deliver the election to Trump, critics began to question what Alexander Nix, the head of Cambridge Analytica, called the firm’s “secret sauce,” the algorithms it used to predict a voter’s psychological profile, what is known as “psychographics.” Confessore and Hakim’s article about the firm, which appeared on the front page of the Times, quoted numerous consultants, working for both parties, who were dismissive of the firm’s claims. The mathematician Cathy O’Neil, in a commentary for Bloomberg, called Cambridge Analytica’s secret sauce “just more ketchup.” Using psychological traits to craft appeals to voters, she wrote, wasn’t anything new—every candidate was doing it.

      Ealiers in 2012 Ethan Roeder (leader of one of the most sopisticated, data-driven campaigns in U.S history) writes in an op-ed in The New York Times:

      How do we predict wheter people are going to vote or not? We look at the voter file. It tells us how often a person votes, althought not for whome. Not all strategists agree about how to interpret this information, but the source of the data is no sectret.

      He articulates limits in general, and that it is limited specifically to information contained in public records. (More in Hacking the Electorate by Eitan D. Hersh p. 12)

      So I wonder if the CA team has so much more to manipulte with in their big database?