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    Trapping a somatic endogenous retrovirus into a germline piRNA cluster immunizes the germline against further invasion
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    pmc.ncbi.nlm.nih.gov/articles/PMC6587276/
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    Hyperandrogenism in polycystic ovary syndrome augments Estrogen synthesis through AR-FOXL2–mediated activation of the aromatase gene in granulosa cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12406384/
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    Vinburnine potentiates anti-PD1 immunotherapy in melanoma through IL-24 secretion via P38/MAPK/ATF3 signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12382293/
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    A novel SOX6 + melanoma cell subtype promotes early microsatellite invasion in Asian acral melanoma through fatty acid transport disorder
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    pmc.ncbi.nlm.nih.gov/articles/PMC12382077/
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    RANBP9 and RANBP10 cooperate in regulating non-small cell lung cancer proliferation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12395873/
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    Senescent fibroblasts secrete CTHRC1 to promote cancer stemness in hepatocellular carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12376455/
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    Obesity enhances ovarian cancer chemotherapy efficacy through C1q-mediated tumor targeting and immune activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12372299/
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    CircZFR/YTHDF3 axis drives lymph node metastasis in cervical cancer via FASN translation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12369095/
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    Atypical cadherin FAT1 promotes tumorigenesis by suppressing autophagic cell death in glioblastoma under hypoxia or nutrient stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC12409952/
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    CCHCR1 links P-body proteins to the centrosome and is required for ciliogenesis through interacting with OFD1 and PCM1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12395705/
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    PTH counteracts Hippo signaling via Src-dependent YAP stabilization to enhance bone marrow stromal cell differentiation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12406730/
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    Ablating UNG activity in a mouse model inhibits colorectal cancer growth by increasing tumor immunogenicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12406714/
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    Cyclin D1 overexpression induces replication stress and microhomology-mediated end-joining dependence in mantle cell lymphoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12404763/
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    The human glucocorticoid receptor variant rs6190 increases blood cholesterol and promotes atherosclerosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12404749/
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    Novel Function for Endothelial Protease-Activated Receptors in Modulating Insulin Receptor Activity With Implications for Diabetes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12321246/
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    An isoform-specific RUNX1C–BTG2 axis governs AML quiescence and chemoresistance.
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    pmc.ncbi.nlm.nih.gov/articles/PMC12405853/
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    Intrinsic Properties of the Lymph Node Render It Immunologically Susceptible to Metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12409284/
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    Mitochondrial glutathione import enables breast cancer metastasis via integrated stress response signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12396134/
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    PKN2 is a dependency of the mesenchymal-like cancer cell state
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    pmc.ncbi.nlm.nih.gov/articles/PMC11875962/
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    PIN1 prolyl isomerase promotes initiation and progression of bladder cancer through the SREBP2-mediated cholesterol biosynthesis pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11875963/
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    Novel Chimeric CTLA-4 B-cell Epitope Peptide Vaccines Demonstrate Effective Antitumor Immunity with/without PD1/PDL1 Blockade in Multiple Syngeneic Murine Models of Breast and Colorectal Cancers
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    Resilience and vulnerabilities of tumor cells under purine shortage stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC12399269/
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    B7-H3 CAR T-cells are effective against ependymomas, but limited by tumor size and immune response
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    pmc.ncbi.nlm.nih.gov/articles/PMC12402791/
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    NF1 Loss Promotes EGFR Activation and Confers Sensitivity to EGFR Inhibition in NF1 Mutant Melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12221223/
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    Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11875910/
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    A Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth and Induces Antitumor Immunity in Gastrointestinal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11875992/
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    Recycling endosomes in mature epithelia restrain tumorigenic signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC6726494/
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    Hypertensive BPH/2J Mice Exhibit Sex-Specific Heart Failure Progression and Late-Life Microvascular Rarefaction
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    pmc.ncbi.nlm.nih.gov/articles/PMC12372015/
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    Preclinical evaluation of antitumor activity and toxicity of TROP2-specific CAR-T cells for treatment of triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12410632/
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    CD24 recruits tumor-associated neutrophils to promote the progression of hepatocellular carcinoma
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    Single-cell analysis of yeast surface display for designer cellulosome applications using a fluorescent protein complex
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    Human endogenous retrovirus K (HERV-K) envelope structures in pre- and postfusion by cryo-EM
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    pmc.ncbi.nlm.nih.gov/articles/PMC12383274/
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    Putative PINK1/Parkin activators lower the threshold for mitophagy by sensitizing cells to mitochondrial stress
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    Deltex and RING-UIM E3 ligases cooperate to create a ubiquitin-ADP-ribose hybrid mark on tankyrase, promoting its stabilization
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    PhoCoil: A photodegradable and injectable single-component recombinant protein hydrogel for minimally invasive delivery and degradation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12383250/
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    Elucidating tissue and subcellular specificity of the entire SUMO network reveals how stress responses are fine-tuned in a eukaryote
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    Architectural transcription factors collectively shape nuclear radial positioning of chromatin contacts
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    Cytoskeletal control in adult microglia is essential to restore neurodevelopmental synaptic and cognitive deficits
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    DKC1-mediated pseudouridylation of rRNA targets hnRNP A1 to sustain IRES-dependent translation and ATF4-driven metabolic adaptation
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    Neuropeptide dynamics coordinate layered plasticity mechanisms adapting Drosophila circadian behavior to changing environment
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    Piezo1 is an essential player in volume regulation of human glioblastoma cells
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    A visual monitoring DNA‐free multi‐gene editing system excised via LoxP::FRT/FLP in poplar
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    Cas9‐ and Cas12a‐mediated excision and replacement of the celiac disease‐related α‐gliadin immunogenic complex in hexaploid wheat
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    <em>Journal of Neuroendocrinology</em> | BSN Journal | Wiley Online Library
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    pmc.ncbi.nlm.nih.gov/articles/PMC12404905/
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    Mutation of Brain Aromatase Impairs Behavior and Neuroplasticity in Adult Zebrafish
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    ApoE4 Upregulates GSK‐3β to Aggravate Alzheimer‐Like Pathologies and Cognitive Impairment in Type 2 Diabetic Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12409304/
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    Polarity Gene PARD6B Promotes Tumor Growth of Colorectal Cancer via Increasing MYC Expression
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    Dietary yeast influences ethanol sedation in Drosophila via serotonergic neuron function
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    Aging‐induced Akt activation involves in aging‐related pathologies and Aβ‐induced toxicity
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    Estrogen-induced chromatin looping changes identify a subset of functional regulatory elements
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    NOTCH1 S2513 is critical for the regulation of NICD levels impacting the segmentation clock in hiPSC-derived PSM cells and somitoids
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    Synthetic yeast genome SCRaMbLEing uncovers a new role for ribosomal proteins in genetic code expansion
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    biorxiv.org/content/10.1101/2025.08.31.673356v1
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    Regulatory Role for Tumor Suppressor REST on Estrogen Receptor (ESR1) Expression and Leiomyoma Pathophysiology
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    biorxiv.org/content/10.1101/2025.08.29.673140v1
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    Combined multi-color immunofluorescence staining and spatial in situ mRNA expression analysis identifies potential fibrosis drivers in acute lymphoblastic leukemia
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    Clock Modulation by Naringenin via RORα Suppresses Lipogenesis and Promotes Adipose Tissue Browning
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    A Common PD-Risk GBA1 Variant Disrupts LIMP2 Interaction, Impairs Glucocerebrosidase Function, and Drives Lysosomal and Mitochondrial Dysfunction
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    2025.08.28.672784v1.full-html.html
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    Event-triggered MINFLUX microscopy: smart microscopy to catch and follow rare events
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    biorxiv.org/content/10.1101/2025.08.27.672674v1
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    Evidence of spinal cord comparator modules for rapid corrections of movements
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    biorxiv.org/content/10.1101/2025.08.27.672590v1
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    Evaluating Flavoprotein Fluorescence Imaging as a Biomarker of Early Retinal Ganglion Cell Mitochondrial Stress
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    HCN channels reveal conserved and divergent physiology in supragranular pyramidal neurons in primate species
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    Dopamine supports reward prediction to constrain reward seeking
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    CRISPR-Cas13d-Mediated Targeting of a Context-Specific Essential Gene Enables Selective Elimination of Uveal Melanoma
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    α-catenin phosphorylation is actomyosin-sensitive and required for epithelial barrier functions through Afadin
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    2025.08.21.671527v1.full-html.html
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    Active learning-guided optimization of cell-free biosensors for lead testing in drinking water
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    Characterization of membrane structures regulating primary ciliogenesis by quantitative isotropic ultrastructure imaging
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    RAB5 NUCLEOTIDE BINDING PROMOTES β-OXIDATION TO FUEL HEPATOCELLULAR CARCINOMA CELL PROLIFERATION
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    Intron retention regulates STAT2 function and predicts immunotherapy response in lung cancer
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    MCA: A Multicellular analysis Calcium Imaging toolbox for ImageJ
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    Clustering within a single-component biomolecular condensate
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    Endogenous Real Time Imaging Reveals Dynamic Chromosomal Mobility During Ligand-Mediated Transcriptional Burst Events
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    Characterizing the Ion-Conductive State of the α7-Nicotinic Acetylcholine Receptor via Single-Channel Measurements and Molecular Dynamics Simulations
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    pmc.ncbi.nlm.nih.gov/articles/PMC12393385/
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    A minimal model for the role of Rim4 in regulating meiotic exit in budding yeast
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    Targeting FSP1 triggers ferroptosis in lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12363832/
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    Organelle bridges and nanodomain partitioning govern targeting of membrane-embedded proteins to lipid droplets
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    pmc.ncbi.nlm.nih.gov/articles/PMC12393287/
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    Comparative transcriptomics reveals context- and strain-specific regulatory programmes of Agrobacterium during plant colonization
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    pmc.ncbi.nlm.nih.gov/articles/PMC12373482/
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    Functional disruption of oxytocin projections participates atypical social and anxiety-like behaviours in BTBR mouse model of autism
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    pmc.ncbi.nlm.nih.gov/articles/PMC12380489/
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    Autophagy Protease ATG4D Facilitates Proliferation and Malignancy of Osteosarcoma Cells
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    Chimeric Vesicular Stomatitis Virus Bearing Western Equine Encephalitis Virus Envelope Proteins E2-E1 Is a Suitable Surrogate for Western Equine Encephalitis Virus in a Plaque Reduction Neutralization Test
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    Circular RNA hsa_circ_0099188 Regulates Inducible Nitric Oxide Synthase and Chemokine Transcription in Macrophages by Targeting the hsa-miR-381-3p/PPP3CA and hsa-miR-381-3p/KLF4 Pathways in Response to 4,4’-Methylene Diphenyl Diisocyanate-Glutathione Conjugate Exposure
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    pmc.ncbi.nlm.nih.gov/articles/PMC12406230/
  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SMAD3 and p300 complex scaffolding by long non-coding RNA LIMD1-AS1 promotes TGF-β-induced breast cancer cell plasticity
    7
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    pmc.ncbi.nlm.nih.gov/articles/PMC12400928/
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Utilizing serum-derived lipidomics with protein biomarkers and machine learning for early detection of ovarian cancer in the symptomatic population
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12409608/
  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Composition and RNA binding specificity of metazoan RNase MRP
    6
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    pmc.ncbi.nlm.nih.gov/articles/PMC12390755/
  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    G-quadruplex-dependent transcriptional regulation by molecular condensation in the Bcl3 promoter
    3
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    pmc.ncbi.nlm.nih.gov/articles/PMC12397910/
  88. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TDP-43 binds to RNA G-quadruplex structure and regulates mRNA stability and translation
    3
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    pmc.ncbi.nlm.nih.gov/articles/PMC12407096/
  89. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A direct interaction between the Chd1 CHCT domain and Rtf1 controls Chd1 distribution and nucleosome positioning on active genes
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12390759/