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  1. Feb 2021
    1. The Covid-19 pandemic has caused major changes to family life followed by a call for knowledge about how these changes have affected parental functioning, particularly in vulnerable families (Prime, Wade & Brooks, 2020). This study uses a natural experiment design to investigate the effect of the Covid-19 lockdown on parental mental health, parenting stress and three dimensions of destructive interparental conflict in a heterogeneous sample characterized by pre-existing relationship problems. Results from mixed model regression analyses showed that despite significantly higher levels of parenting stress in the lockdown group (n = 744 families) compared with the control group (n = 427 families), lockdown did not adversely affect parental mental health or levels of destructive conflicts behaviors. In fact, levels of verbal aggression and child involvement in conflict decreased during lockdown among parents living apart. Pre-existing destructive conflict levels, financial problems and age of youngest child did not moderate any of the associations. Thus, findings indicated that pre-existing family vulnerability did not predispose for reduced parental functioning during lockdown, beyond increased parenting stress. Resilient processes and an increased sense of purpose may be potential mechanisms. Caution should be taken when generalizing the findings due to the welfare context of the sample and as long-term lockdown effects were not investigated. Importantly, children in vulnerable families may have been negatively impacted by increased family time, despite relatively stable parental functioning during lockdown.
    1. Behavioural science has been effectively used by policy makers in various domains, from health to savings. However, interventions that behavioural scientists typically employ to change behaviour have been at the centre of an ethical debate, given that they include elements of paternalism that have implications for people’s freedom of choice. In the present article, we argue that this ethical debate could be resolved in the future through implementation and advancement of new technologies. We propose that several technologies which are currently available and are rapidly evolving (i.e., virtual and augmented reality, social robotics, gamification, self-quantification, and behavioural informatics) have a potential to be integrated with various behavioural interventions in a non-paternalistic way. More specifically, people would decide themselves which behaviours they want to change and select the technologies they want to use for this purpose, and the role of policy makers would be to develop transparent behavioural interventions for these technologies. In that sense, behavioural science would move from libertarian paternalism to liberalism, given that people would freely choose how they want to change, and policy makers would create technological interventions that make this change possible.
    1. In response to the rapid spread of the coronavirus disease 2019 (COVID-19), governments and health-authorities have both recommended and mandated various measures aiming to contain the spread of the virus and, in turn, save lives. Despite generally high levels of compliance with and public support for these measures, several countries have witnessed a recent upsurge in the number of people who no longer sufficiently adhere to the restrictions and keep themselves informed about the pandemic. This developing trend has either been named or attributed to Pandemic Fatigue. Notably, though, a scientific conceptualization, including an identification of Pandemic fatigue and theoretical dissociation from its correlates and outcomes, is completely lacking. Using representative survey data from Denmark and Germany (overall N = 5,841), we introduce a psychometrically sound measure of Pandemic Fatigue, show who experiences it, identify related emotions and perceptions, and reveal its effects on health protective behaviors. We find that Pandemic Fatigue consists of two distinct, yet highly correlated dimensions – Information and Behavioral Fatigue – and that younger, healthier, and less educated people are more likely to experience it. Further, we find that Pandemic Fatigue is related to certain emotions and perceptions that could be targeted through different interventions in an attempt to reinvigorate fatigued individuals. Moreover, we find that Pandemic Fatigue is a strong predictor of nonadherence to health protective measures, even beyond other relevant emotions and perceptions. Taken together, the results call for a multifaceted approach towards keeping public compliance high when facing a pandemic.
    1. Aim and Method: This perspective searches presents evidence of mature gratitude as a way of coping with the threats and boundaries of COVID-19. This narrative, non-systematic review will be based on studies from the COVID-19 period in association with more general literature on the characteristics of mature gratitude related to good mental health. Results: The results from the literature suggest that a confrontation with our existential vulnerability during a pandemic is not only a crisis but also an opportunity to view our lives in a different way. Mature gratitude, as proposed in this perspective, can help us in coping with the threats and boundaries that are part of our lives due to the COVID-19 pandemic. This time of crisis gives us the opportunity to self-reflect on our current life and plans for the future and to reframe them through a positive lens which can encourage individuals to actively strengthen their psychological resilience and coping skills. Conclusion: Cultivating an attitude of mature gratitude through actions of kindness, expressing being thankful for life and God, and enjoying all the small things in life helps in coping with the current threats of COVID-19 and building lifelong resilience for the future Knowledge about these associations can help psychologists, counselors, and coaches to support people who experience psychological issues due to the current pandemic and all crises to come.
    1. There is a global consensus about the potential of the COVID-19 pandemic to affect people's mental health. In this context, and prior to the formulation of mitigation strategies, tools are required that allow an objective and effective assessment of mental health risk. The purpose of this study was to evaluate the psychometric characteristics of COVID-19 Stress Scale, formulated by Taylor et al. (2020), based on the concept of COVID-19 Stress Syndrome. A national sample of 1214 participating adults was taken in Colombia, who answered a translated version of the scale. Evidence of a hexa-dimensional structure was obtained whose goodness of fit indicators were Chi2 = 1215,759, Sig. =. 000, CMIN / DF = 2.202, RMSEA = .044, NFI = .943, TLI = .964, CFI =. 968 and FMIN = 1,967. Regarding reliability, an α = .924 and Spearman-Brown = .824 were obtained for the entire scale; the reliability indicators of the 6 subscales were also high. The similarities and differences in the findings with respect to the original psychometric study of the scale are discussed, as well as the utility and importance of the instrument as a tool in future efforts to mitigate the psychosocial effects of the pandemic
    1. Disinformation is on the rampage with manipulated stories spreading like wildfire on social media. While disinformation has always been with us, the power at which it spreads on social media platforms is new. Since the 2016 US election, the term’s appearance in news headlines has grown tenfold.
    1. A significant number of Americans believe misinformation about the origins of the coronavirus and the recent presidential election, as well as conspiracy theories like QAnon, according to a new NPR/Ipsos poll.
    1. The COVID-19 pandemic and countermeasures implemented by governments around the world have led to dramatically increased symptoms of depression and anxiety. Pregnant women may be particularly vulnerable to the negative psychological effects of COVD-19 public health measures, because they represent a demographic that is most affected by disasters and because pregnancy itself entails significant life changes that require major psychosocial and emotional adjustments. The Pregnancy During the COVID-19 Pandemic (PdP) study was designed to investigate the associations between exposure to objective hardship caused by the pandemic, perceived stress and psychological distress in pregnant individuals, and developmental outcomes in their offspring. Methods The PdP study comprises a prospective longitudinal cohort of pregnant individuals (at enrollment) with repeated follow-ups during pregnancy and the postpartum period. Participants were eligible if they were: pregnant, ≥17 years, ≤35 weeks gestation at study enrollment, living in Canada, and able to read and write in English or French. Participant recruitment via social media (Facebook, Instagram) began on April 5, 2020 and is ongoing. At enrollment, participants completed an initial survey that assessed demographic and socioeconomic characteristics, previous pregnancies and births, pre-pregnancy health, health conditions during pregnancy, medications, psychological distress, social support, and hardships experienced because of COVID-19 (e.g., lost employment, loved one dying). For the first three months following the initial survey, participants received a monthly email link to complete a follow-up survey that asked about experiences since the previous survey. After three months, follow-up surveys were sent bi-monthly to reduce participant burden. For each of these surveys, participants were first asked if they were still pregnant and then routed either to the next prenatal survey or to the delivery survey. In the postpartum, surveys were sent at 3-, 6-, and 12-months of infant age to assess maternal psychological distress and infant development. Discussion This longitudinal investigation seeks to elucidate the associations between hardships, maternal psychological distress, child development during COVID-19, and risk and resilience factors that amplify or ameliorate these associations. Findings are intended to generate knowledge about the psychological consequences of pandemics on pregnant individuals and point toward prevention and intervention targets.
    1. A reliable measure to evaluate the predictive accuracy of a theoretical construct should be independent of the empirical setting in which the construct is tested. Effect size measures such as Cohen’s d, widely used for this very purpose today, instead plague this evaluation with ambiguity. Evaluating a theoretically postulated effect size in view of an empirically observed standard deviation—as Cohen’s d requires—is particularly inadequate when the empirical adequacy of a theoretical construct must be evaluated across empirical settings. As an improved measure, the similarity index compares the theoretically predicted effect size directly to the empirically observed effect size. Their similarity thus informs the construct’s empirical adequacy. Based on computer simulations, we propose a specific similarity interval as useful for theory-construction. We illustrate the similarity index using select findings from social and personality psychology, and describe its application in different empirical research designs.
    2. A reliable measure to evaluate the predictive accuracy of a theoretical construct should be independent of the empirical setting in which the construct is tested. Effect size measures such as Cohen’s d, widely used for this very purpose today, instead plague this evaluation with ambiguity. Evaluating a theoretically postulated effect size in view of an empirically observed standard deviation—as Cohen’s d requires—is particularly inadequate when the empirical adequacy of a theoretical construct must be evaluated across empirical settings. As an improved measure, the similarity index compares the theoretically predicted effect size directly to the empirically observed effect size. Their similarity thus informs the construct’s empirical adequacy. Based on computer simulations, we propose a specific similarity interval as useful for theory-construction. We illustrate the similarity index using select findings from social and personality psychology, and describe its application in different empirical research designs.
    1. My team at the Genomics UK consortium sequenced the new Sars-CoV-2 variant, but we’ll need more evidence to understand how it might change the pandemic
    1. A coronavirus variant that probably emerged in May and surged to become the dominant strain in California not only spreads more readily than its predecessors but also evades antibodies generated by COVID-19 vaccines or prior infection and is associated with severe illness and death, researchers said.
    1. We develop a two strain, age-structured, compartmental model to assess the spreading potential of the B.1.1.7 variant across several European metropolitan areas and countries. The model accounts for B.1.1.7 introductions from the UK and different locations, as well as local mitigation policies in the time period 2020/09-2021/02. In the case of an increase of transmissibility of 50%, the B.1.1.7 variant has the potential to become dominant in all investigated areas by the end of March 2021
    1. Human behaviors determine outbreak trajectories of infectious diseases. This fundamental relationship underlies why broad behavioral interventions (BIs) are effective tools in outbreak management. BIs target an overall reduction in contacts and behaviors that enable pathogen transmission as a nonspecific solution for preventing new infections. Despite that, there is a lot that remains unknown about the interactions between human behavior and infectious diseases. These gaps limit targeted outbreak management and prevention. In PNAS, Vigfusson et al. (1) narrow this gap by exploring multiple ways to assess behavioral changes in infectious hosts using existing data sources. By linking mobile-phone call detail records (CDRs) with health records of clinically confirmed influenza, they measure deviations in routine behaviors during illness compared to pre- and postillness behaviors.
    1. Besonders in Zeiten einer Pandemie wie der von COVID-19 nimmt das allgemeine Stressniveau der Betroffenen stark zu. Verschiedene Faktoren tragen besonders in einer so außergewöhnlichen Situation vermehrt zu Stress bei. So können mit der Pandemie verbundene Einschränkungen wie eine Kontaktreduzierung, das Tragen von Mund-Nasen-Masken oder auch die Schließung öffentlicher Einrichtungen auch psychisch eine starke Beeinträchtigung bedeuten.
    1. There has been a huge amount of misinformation during the pandemic. Much of it was unavoidable, especially at the start as we dealt with a new virus, but some myths are persisting a year into the pandemic. The myths range from the ridiculous to the merely implausible, but together they are misleading the public about the danger of Covid-19 and other variants. These false claims could also have serious consequences, such as fuelling premature calls to end social distancing measures before the vaccination rollout has reached a safe level.  To combat some of this misinformation, a group of scientists, journalists, economists and other researchers have created Anti-Virus, a website that tries to address the biggest myths surrounding the pandemic, and highlight claims or points of view that have been expressed by figures in academia or the media that are no longer credible. 
    1. This short, online course builds on a similar course offered to Indian & African health journalists, will introduce epidemiologic concepts to health/science journalists. The course will use topical examples from COVID-19, to cover issues such as types of epidemiologic studies, how to measure disease frequency and risk, importance of bias and confounding, and review various common study designs, including observational studies and randomized trials. The main emphasis would be on how to critically read literature and how to report accurately.
    1. Biologists​  love abbreviations, but we often use them clumsily. What may sound like catchy acronyms to one group of researchers are tiresome jargon to colleagues in related fields. Fruit fly geneticists have taken whimsy to absurdity: MAD stands for ‘Mothers Against Decapentaplegic’. The ‘decapentaplegic’ bit comes from a mutant fly that doesn’t correctly form fifteen (deca-penta) important structures that go on to become legs, wings, antennae etc. The ‘Mothers Against’ bit is a joke that may have been funny in 1995. Immunologists tend towards the impenetrably boring. We’ve named messenger molecules between white blood cells ‘interleukins’, and given each of them a natural number. Logical enough, but we’ve now got up to IL38, and it’s almost impossible to recall what each of them does. Not to be outdone, molecular epidemiologists have come up with such names as B.1.1.7. That’s the Sars-CoV-2 variant now dominating the pandemic in the UK (and Ireland, Denmark, Israel and soon Germany and much of the rest of the world). The variant that’s dominating in South Africa is B.1.351, or 20H/501Y.V2 if you prefer. At least in Brazil what would have been B.1.1.28.P1 has been allowed to drop its cumbersome honorific and become plain old P1.
    1. Low birth weight (LBW) infants have lower infant mortality in groups in which LBW is most frequent. For example, in 1991, US infants born to smokers had higher risks of both LBW and infant mortality than infants born to nonsmokers. However, among LBW infants, infant mortality was lower for infants born to smokers (relative rate = 0.79). There are competing theories regarding this so-called “paradox.” One is that maternal smoking is beneficial for LBW infants. The authors use causal diagrams to show that, even in the absence of any beneficial effect of smoking, an inverse association due to stratification on birth weight can be found. This variable is affected by the exposure of interest and shares common causes with the outcome. That is, LBW infants born to smokers may have a lower risk of mortality than other LBW infants whose LBW is due to causes associated with high mortality (e.g., birth defects). Under realistic causal diagrams, adjustment for birth weight is unwarranted when the analytical goal is to estimate overall effects of prenatal variables on infant mortality. Even for estimating direct effects of prenatal variables, adjustment for birth weight may be invalid when there is an unmeasured common cause of LBW and mortality. An appropriate justification for conditioning on birth weight requires specifying 1) the causal question motivating this analytical approach and 2) the assumptions regarding the proposed underlying biologic mechanisms.
    1. The Jeffreys–Lindley paradox displays how the use of a 𝑝pp value (or number of standard deviations 𝑧zz) in a frequentist hypothesis test can lead to an inference that is radically different from that of a Bayesian hypothesis test in the form advocated by Harold Jeffreys in the 1930s and common today. The setting is the test of a well-specified null hypothesis (such as the Standard Model of elementary particle physics, possibly with “nuisance parameters”) versus a composite alternative (such as the Standard Model plus a new force of nature of unknown strength). The 𝑝pp value, as well as the ratio of the likelihood under the null hypothesis to the maximized likelihood under the alternative, can strongly disfavor the null hypothesis, while the Bayesian posterior probability for the null hypothesis can be arbitrarily large. The academic statistics literature contains many impassioned comments on this paradox, yet there is no consensus either on its relevance to scientific communication or on its correct resolution. The paradox is quite relevant to frontier research in high energy physics. This paper is an attempt to explain the situation to both physicists and statisticians, in the hope that further progress can be made.
    1. The gambler's fallacy, also known as the Monte Carlo fallacy or the fallacy of the maturity of chances, is the erroneous belief that if a particular event occurs more frequently than normal during the past it is less likely to happen in the future (or vice versa), when it has otherwise been established that the probability of such events does not depend on what has happened in the past. Such events, having the quality of historical independence, are referred to as statistically independent. The fallacy is commonly associated with gambling, where it may be believed, for example, that the next dice roll is more than usually likely to be six because there have recently been fewer than the usual number of sixes.
    1. The “prosecutor's fallacy” (the assumption that Pr [probability] (A|B) = Pr (B|A)) arises often in epidemiology but is often unrecognized as such, in part because investigators do not have strong intuitions about what the fallacy means. Here, we help inform such intuitions and remind investigators of this fallacy by using visualizations. In figures, we demonstrate the prosecutor's fallacy, as well as show conditions under which Pr (A|B) can be assumed to be equal to Pr (B|A). Visualizations can help build intuition around statistical concepts such as the prosecutor's fallacy and should be more widely considered as teaching tools.
    1. Numerous observational studies have attempted to identify risk factors for infection with SARS-CoV-2 and COVID-19 disease outcomes. Studies have used datasets sampled from patients admitted to hospital, people tested for active infection, or people who volunteered to participate. Here, we highlight the challenge of interpreting observational evidence from such non-representative samples. Collider bias can induce associations between two or more variables which affect the likelihood of an individual being sampled, distorting associations between these variables in the sample. Analysing UK Biobank data, compared to the wider cohort the participants tested for COVID-19 were highly selected for a range of genetic, behavioural, cardiovascular, demographic, and anthropometric traits. We discuss the mechanisms inducing these problems, and approaches that could help mitigate them. While collider bias should be explored in existing studies, the optimal way to mitigate the problem is to use appropriate sampling strategies at the study design stage.
    1. Background In a famous article, Simpson described a hypothetical data example that led to apparently paradoxical results.Methods We make the causal structure of Simpson's example explicit.Results We show how the paradox disappears when the statistical analysis is appropriately guided by subject-matter knowledge. We also review previous explanations of Simpson's paradox that attributed it to two distinct phenomena: confounding and non-collapsibility.Conclusion Analytical errors may occur when the problem is stripped of its causal context and analyzed merely in statistical terms.
    1. Previous posts[a],[b],[c] of mine have considered Lord’s Paradox. To recap, this was considered in the form described by Wainer and Brown[1], in turn based on Lord’s original formulation: A large university is interested in investigating the effects on the students of the diet provided in the university dining halls : : : . Various types of data are gathered. In particular, the weight of each student at the time of his arrival in September and his weight the following June are recorded. [2](p. 304)
    1. In 19th century Europe, suicide rates were higher in countries that were more heavily Protestant,the inference being that suicide was promoted by the social conditions of Protestantism (Durkheim1897; also see Neeleman and Lewis 1999). According to Carroll (1975), death rates from breastcancer are higher in countries where fat is a larger component of the diet, the idea being that fatintake causes breast cancer. These are ‘ecological inferences,’ that is, inferences about individualbehavior drawn from data about aggregates.
    1. The non-equivalence of statistical significance and clinical importance has long been recognised, but this error of interpretation remains common. Although a significant result in a large study may sometimes not be clinically important, a far greater problem arises from misinterpretation of non-significant findings. By convention a P value greater than 5% (P>0.05) is called “not significant.” Randomised controlled clinical trials that do not show a significant difference between the treatments being compared are often called “negative.” This term wrongly implies that the study has shown that there is no difference, whereas usually all that has been shown is an absence of evidence of a difference. These are quite different statements.
    1. Report from by the INI Higher Education Working Group on COVID-19 and universities. It was considered at SAGE 76 on 14 January 2021. The paper is the assessment of the evidence at the time of writing. As new evidence or data emerges, SAGE updates its advice accordingly. See further information on the new SARS-CoV-2 variant. This paper should be read alongside ‘SPI-B: Return to campus for Spring term: risk of increased transmission from student migration’ from SAGE 76 on 14 January 2021. More details and an updated version of this analysis is available as a preprint on the Isaac Newton Institute website (PDF). These documents are released as pre-print publications that have provided the government with rapid evidence during an emergency. These documents have not been peer-reviewed and there is no restriction on authors submitting and publishing this evidence in peer-reviewed journals. Redactions have been made to remove figures containing statistically disclosive or identifiable data.
    1. Paper by TFC updating their paper of 17 December 2020 on children, schools and transmission. It was considered at SAGE 80 on 11 February 2021. This paper should be read alongside the Juniper consortium paper on the impact of partial school openings, also presented at SAGE 80. These documents are released as pre-print publications that have provided the government with rapid evidence during an emergency. These documents have not been peer-reviewed and there is no restriction on authors submitting and publishing this evidence in peer-reviewed journals.
    1. Im Streit um Restaurant- und Ladenöffnungen geht eines unter: Die Schweiz hat keine Strategie, um mit dem Virus umzugehen.
    1. Experts are often asked to represent their uncertainty as a subjective probability. Structured protocols offer a transparent and systematic way to elicit and combine probability judgements from multiple experts. As part of this process, experts are asked to individually estimate a probability (e.g., of a future event) which needs to be combined/aggregated into a final group prediction. The experts' judgements can be aggregated behaviourally (by striving for consensus), or mathematically (by using a mathematical rule to combine individual estimates). Mathematical rules (e.g., weighted linear combinations of judgments) provide an objective approach to aggregation. However, the choice of a rule is not straightforward, and the aggregated group probability judgement's quality depends on it. The quality of an aggregation can be defined in terms of accuracy, calibration and informativeness. These measures can be used to compare different aggregation approaches and help decide on which aggregation produces the "best" final prediction. In the ideal case, individual experts' performance (as probability assessors) is scored, these scores are translated into performance-based weights, and a performance-based weighted aggregation is used. When this is not possible though, several other aggregation methods, informed by measurable proxies for good performance, can be formulated and compared. We use several data sets to investigate the relative performance of multiple aggregation methods informed by previous experience and the available literature. Even though the accuracy, calibration, and informativeness of the majority of methods are very similar, two of the aggregation methods distinguish themselves as the best and worst.
    1. Air New Zealand will trial a digital vaccine passport in April on flights between Auckland and Sydney with Qantas investigating similar technology.As vaccination begins in Australia, attention has turned to the potential resumption of international travel and how Australia could track whether potential visitors have been vaccinated.Several tech companies have been working with the World Health Organization to develop a secure digital vaccination record system that could be used to prove to airlines and governments that passengers have had a Covid vaccine.
    1. What is already known about this topic? Two COVID-19 vaccines have received Emergency Use Authorization for administration in the United States. In preauthorization clinical trials, local and systemic reactions were reported; no serious safety problems were detected. What is added by this report? Monitoring, conducted as part of the U.S. vaccination program, indicates reassuring safety profiles for COVID-19 vaccines. Local and systemic reactions were common; rare reports of anaphylaxis were received. No unusual or unexpected reporting patterns were detected. What are the implications for public health practice? Health care providers and vaccine recipients can be reassured about the safety of Pfizer BioNTech and Moderna COVID-19 vaccines. Counseling vaccine recipients to expect transient local and systemic reactions might ease concerns and encourage completion of the 2-dose vaccination series.
    1. New pledges by leaders of the G7 group of richest countries to intensify cooperation on covid-19 and commit $7.5bn (£5.3bn; €6.2bn) to sharing supplies of vaccine around the world are insufficient, a leading charity has said.Oxfam said that steps to increase the supply of vaccines to poorer countries, though welcome, would not be enough to deal with the covid-19 threat and to redress “immoral” inequalities of access.Meanwhile, the UK is being urged to act more quickly on its commitment to make “surplus” vaccines available to developing countries and to explain when it would have spare doses.
    1. Paul Hoyningen-Huene argues that what makes scientific knowledge special is its systematic character, and that this can be used to solve the demarcation problem. He labels this STDC: “Systematicity Theory’s Demarcation Criterion.” This paper argues that STDC fails, because there are areas of intellectual activity that are highly systematic, but that the great majority of scientists and historians and philosophers of science do not accept as scientific. These include homepathy, creationism, and climate change denial. I designate these activities “facsimile sciences” because they mimic the appearance of science but are not, by the standards of philosophers and scientists, scientific. This suggests that we need additional criteria to demarcate science from non-science and/ or nonsense.
    1. Prior research has indicated that disease threat and disgust are associated with harsher moral condemnation. We investigated the role of a specific, highly salient health concern, namely the spread of the coronavirus, and associated COVID-19 disease, on moral condemnation. We hypothesized that individuals who report greater subjective worry about COVID-19 would be more sensitive to moral transgressions. Across 3 studies (N = 913), conducted March-May 2020 as the pandemic started to unfold in the United States, we found that individuals who were worried about contracting the infectious disease made harsher moral judgments than those who were relatively less worried. This effect was not restricted to transgressions involving purity, but extended to transgressions involving harm, fairness, authority, and loyalty, and remained when controlling for political orientation. Furthermore, for Studies 1 and 2 the effect also was robust when taking into account the contamination subscale of the Disgust Scale—Revised. These findings add to the growing literature that concrete threats to health can play a role in abstract moral considerations, supporting the notion that judgments of wrongdoing are not based on rational thought alone.
    1. SummaryBackgroundWuhan was the first epicentre of COVID-19 in the world, accounting for 80% of cases in China during the first wave. We aimed to assess household transmissibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and risk factors associated with infectivity and susceptibility to infection in Wuhan.MethodsThis retrospective cohort study included the households of all laboratory-confirmed or clinically confirmed COVID-19 cases and laboratory-confirmed asymptomatic SARS-CoV-2 infections identified by the Wuhan Center for Disease Control and Prevention between Dec 2, 2019, and April 18, 2020. We defined households as groups of family members and close relatives who did not necessarily live at the same address and considered households that shared common contacts as epidemiologically linked. We used a statistical transmission model to estimate household secondary attack rates and to quantify risk factors associated with infectivity and susceptibility to infection, accounting for individual-level exposure history. We assessed how intervention policies affected the household reproductive number, defined as the mean number of household contacts a case can infect.Findings27 101 households with 29 578 primary cases and 57 581 household contacts were identified. The secondary attack rate estimated with the transmission model was 15·6% (95% CI 15·2–16·0), assuming a mean incubation period of 5 days and a maximum infectious period of 22 days. Individuals aged 60 years or older were at a higher risk of infection with SARS-CoV-2 than all other age groups. Infants aged 0–1 years were significantly more likely to be infected than children aged 2–5 years (odds ratio [OR] 2·20, 95% CI 1·40–3·44) and children aged 6–12 years (1·53, 1·01–2·34). Given the same exposure time, children and adolescents younger than 20 years of age were more likely to infect others than were adults aged 60 years or older (1·58, 1·28–1·95). Asymptomatic individuals were much less likely to infect others than were symptomatic cases (0·21, 0·14–0·31). Symptomatic cases were more likely to infect others before symptom onset than after (1·42, 1·30–1·55). After mass isolation of cases, quarantine of household contacts, and restriction of movement policies were implemented, household reproductive numbers declined by 52% among primary cases (from 0·25 [95% CI 0·24–0·26] to 0·12 [0·10–0·13]) and by 63% among secondary cases (from 0·17 [0·16–0·18] to 0·063 [0·057–0·070]).InterpretationWithin households, children and adolescents were less susceptible to SARS-CoV-2 infection but were more infectious than older individuals. Presymptomatic cases were more infectious and individuals with asymptomatic infection less infectious than symptomatic cases. These findings have implications for devising interventions for blocking household transmission of SARS-CoV-2, such as timely vaccination of eligible children once resources become available.FundingNational Natural Science Foundation of China, Fundamental Research Funds for the Central Universities, US National Institutes of Health, and US National Science Foundation.
    1. Covid-19 is a respiratory disease caused by the severe acute respiratory syndrome coronavirus – 2 (SARS-CoV-2), which was first identified in Wuhan China in December 2019. Because of Covid-19 worldwide spreading in 2020, urgent hygiene and lockdown measures have been implemented with fundamental consequences on the lives of people in all sectors of society. Besides visible socio-economic and documented health effects, the impact of Covid-19 on people’s mental health including stress-related effects on disease spreading remains yet to be addressed. Here, we argue about the relevance of incorporating stress factors into models of covid-19 spreading and the level of detail in which such models should take stress into consideration.
    1. Preexisting conditions affect disease susceptibility. Here, I show that socio-cultural values are population-level risk factors for disease. Using data from the World Values Survey, I show that, between 2 weeks and 6 months after the first COVID-19-related death in a country, COVID-19-related mortality is increased in countries endorsing values related to political participation, but decreased in countries with more trust in institutions and materialistic orientations. After controlling for income, age, urbanicity, smoking, overweight, private health expenditure and lockdown delay, these socio-cultural values were consistent across country-sets, reduced prediction errors by up to 52% and explained up to 68% of inter-country variability. They were relatively specific to COVID-19-related mortality. I could not identify values predicting general health outcomes, and values predicting increased COVID-19-related mortality predicted decreased mortality due to other causes like environmental-related mortality, explaining up to 90% of inter-country variability. Socio-cultural values might be specific predictors of health outcomes.
    1. The potential side effects of COVID-19 vaccines Efficacy vs. side effects Severe allergic reactions (“anaphylaxis”) What about long-term side effects? Latest updates (January 2021 onward)
    1. Background. Adverse childhood experiences (ACEs) are associated with poorer adult mental health, and benevolent childhood experiences (BCEs) are associated with better adult mental health. Objective. To test whether ACEs and BCEs predict adult mental health beyond current stress and social support during the COVID-19 pandemic. Participants and Setting. We analyzed data from undergraduate and graduate students (N = 502) at an urban private university in the western United States. Methods. An online survey was conducted to assess ACEs and BCEs, current stress and social support, depressive and anxiety symptoms, perceived stress, and loneliness in May 2020. Results. Higher levels of ACEs were associated with higher levels of depressive symptoms, β = 0.45, p = .002. Higher levels of BCEs were associated with lower depressive symptoms, β = -0.39, p = .03, lower perceived stress, β = -0.26, p = .002, and less loneliness, β = -0.12, p = .04. These associations held while controlling for current stress, social support, and socioeconomic status. Conclusions. Childhood experiences are associated with mental health during the COVID-19 pandemic. BCEs should be considered an important promotive factor, independent of ACEs, for psychological well-being during a global public health crisis. BCEs should be included along with ACEs in future research and screening with distressed and vulnerable populations.
    1. If platforms such as Facebook, Instagram, and Twitter are the engines of social media use, what is the gasoline? The answer can be found in the psychological dynamics behind consumer habit formation and performance. In fact, the financial success of different social media sites is closely tied to the daily‐use habits they create among users. We explain how the rewards of social media sites motivate user habit formation, how social media design provides cues that automatically activate habits and nudge continued use, and how strong habits hinder quitting social media. Demonstrating that use habits are tied to cues, we report a novel test of a 2008 change in Facebook design, showing that it impeded posting only of frequent, habitual users, suggesting that the change disrupted habit automaticity. Finally, we offer predictions about the future of social media sites, highlighting the features most likely to promote user habits.
    1. Errors are an inevitable consequence of human fallibility and researchers are no exception. Most researchers can recall major frustrations or serious time delays due to human errors while collecting, analyzing, or reporting data. The present study is an exploration of mistakes made during the data management process in psychological research. We surveyed 464 researchers regarding the type, frequency, seriousness, and outcome of mistakes that have occurred in their research team during the last 5 years. The majority of respondents suggested that mistakes occurred with very low or low frequency. Most respondents reported that the most frequent mistakes led to insignificant or minor consequences, such as time loss or frustration. The most serious mistakes caused insignificant or minor consequences for about a third of respondents, moderate consequences for almost half of respondents, and major or extreme consequences for about one-fifth of respondents. The most frequently reported types of mistakes were ‘ambiguous naming/defining of data’, ‘incorrect data processing/analysis’, and ‘version control error’. Most mistakes were reportedly due to poor project planning or management and/or personal issues (physical or cognitive constraints). These initial exploratory findings lay the groundwork for a systematic investigation of human fallibility in research data management and the development of solutions that may reduce errors and mitigate their impact.
    1. Millions of people are mourning the death of a loved to COVID-19. According to previous studies, the circumstances of coronavirus disease-related deaths may lead to dysfunctional grief. The purpose of this study was to introduce the Polish adaptation of the Pandemic Grief Scale (PGS) as well as to assess the relationship between dysfunctional grief due to a COVID-19 death, resilience and perceived social support. The adaptation was carried out on a general population sample of 286 individuals aged 18–54 years, with the evaluation being performed on a group comprising 214 people aged 18–78 years, who lost a loved one during the pandemic. The Polish version of PGS revealed a single-factor structure with strong internal consistency (α = 0.89). The PGS scores were associated with measures of complicated grief (Inventory of Complicated Grief), depression (Kutcher Adolescent Depression Scale) and lower resilience (Resilience Scale 14), which confirmed the scale’s convergent validity. No relation between PGS scores and health behaviors (Inventory of Health Behaviors) was observed, which confirmed the scale’s discriminant validity. The results of the bootstrapping technique revealed that resilience mediates the relationship between perceived social support (Multidimensional Scale of Perceived Social Support) and dysfunctional grief (total mediation). The results of this study suggest the need for practitioners to focus on resilience-enhancing interventions and perceived social support in order to improve mental health in people who lost their loved ones during the new coronavirus pandemic.
    1. Psychological science is at an inflection point: The COVID-19 pandemic has already begun to exacerbate inequalities that stem from our historically closed and exclusive culture. Meanwhile, reform efforts to change the future of our science are too narrow in focus to fully succeed. In this paper, we call on psychological scientists—focusing specifically on those who use quantitative methods in the United States as one context in which such a conversation can begin—to reimagine our discipline as fundamentally open and inclusive. First, we discuss who our discipline was designed to serve and how this history produced the inequitable reward and support systems we see today. Second, we highlight how current institutional responses to address worsening inequalities are inadequate, as well as how our disciplinary perspective may both help and hinder our ability to craft effective solutions. Third, we take a hard look in the mirror at the disconnect between what we ostensibly value as a field and what we actually practice. Fourth and finally, we lead readers through a roadmap for reimagining psychological science in whatever roles and spaces they occupy, from an informal discussion group in a department to a formal strategic planning retreat at a scientific society.
    1. Differences in political ideology are increasingly appearing as an impediment to successful bipartisan communication from local leadership. For example, recent empirical findings have shown that conservatives are less likely to adhere to COVID-19 health directives. This behavior is in direct contradiction to past research which indicates that conservatives are more rule abiding, prefer to avoid loss, and are more prevention-motivated than liberals. We reconcile this disconnect between recent empirical findings and past research by using insights gathered from press releases, millions of tweets, and mobility data capturing local movement in retail, grocery, workplace, parks, and transit domains during COVID-19 shelter-in-place orders. We find that conservatives adhere to health directives when they express more fear of the virus. In order to better understand this phenomenon, we analyze both official and citizen communications and find that press releases from local and federal government, along with the number of confirmed COVID-19 cases, lead to an increase in expressions of fear on Twitter.
    1. Misinformation on COVID-19 is so pervasive that even some patients dying from the disease still say it’s a hoax. In March 2020, nearly 30% of U.S. adults believed the Chinese government created the coronavirus as a bioweapon (Social Science & Medicine, Vol. 263, 2020) and in June, a quarter believed the outbreak was intentionally planned by people in power (Pew Research Center, 2020).
    1. The sudden restrictions — announced after the official death toll nearly doubled — could upend the travel plans of millions of Chinese citizens, who travel in huge numbers during the Lunar New Year holiday.
    1. Greetings from Beijing, China! By now you have most likely heard of the coronavirus outbreak that has originated in Wuhan and has spread all over the country and internationally. I am currently studying abroad in Beijing and traveled to Harbin for the first few days of the Chinese New Year holiday, but have now gathered back in Beijing at the request of CET and the Middlebury Schools Abroad.  While I am by no means a public health expert, I have been keeping up to date with both Western and Chinese media and the U.S. Embassy and have written notes each day for the past week with updates. These reports include my own observations, as well as reports from over 500 contacts on the ground. You can follow the whole set below.
    1. The technology could revolutionize efforts to immunize against HIV, malaria, influenza and more.
    1. There are 4 variants of concern,designated:•VOC202012/01(B.1.1.7), first detected in KentEnglandis predominant in all regionsand is circulating inmultiple countries•VOC 202102/02(B.1.1.7 cluster with E484K mutation), first detected in South West Englandhas been detected in 23cases•VOC202012/02(B.1.351), first detected in South Africa, 126case havebeen detected in England with evidence of in country transmission.Local testing is underway and links between cases are being investigated•VOC202101/02(P.1),firstdetected inBrazilhas not been detected in the UK
    1. Background: In the unpredictable times of the ongoing global coronavirus disease (COVID-19), parents worldwide are affected by stressors and strains that follow in the wake of the government-initiated distancing protocols. Objective: In a two‐wave longitudinal survey, we examined levels of parental perceived stress and symptoms of anxiety and depression among a sample of parents at two time points; in the midst of the strictest government-initiated physical distancing protocols following the onset of the COVID-19 pandemic (T1, N = 2868) and three months after the protocols discontinued (T2, n = 1489). Further, we investigated the levels of parental stress, anxiety, and depression relative to perceived relationship quality and anger aimed at child(ren) at the two time points, including subgroups based on age, sex, cultural background, civil status, education level, number of children in household, employment status, and pre-existing psychiatric diagnosis. Methods and findings: Parents were asked to fill out a set of validated questionnaires on the two measurement occasions. As expected, the findings indicate that the high levels of parental stress significantly decreased from T1 to T2, indicating that the cumulative stressors that parent’s experiences during distancing protocols declined as a function of the phaseout of the protocols. The decrease of perceived parental stress at the two time points, was accompanied by a significant decrease in symptoms of both depression and anxiety among the participating parents. Symptoms meeting the clinical cut-off for depression (23.0%) and generalized anxiety disorder (23.3%) were reported among participating parents at T1, compared to 16.8% and 13.8% respectively at T2. Reduction in depression and angry at child(ren) from T1 to T2 were further associated with a reduction in perceived parental stress. In addition, relationship quality and angry at child(ren) at T1 predicted change in parental stress. Conclusions: The findings underline some of the negative psychological impact of physical distancing protocols on parent’s health and well-being. Parents who are facing physical distancing and remaining at home with their children may be particularly vulnerable to parental stress, anxiety and depression. Uncovering the nature of how these constructs are associated to parents and families facing social crisis, such as the ongoing pandemic, can contribute to design relevant interventions to reduce parental stress and strengthen parental coping and resilience.
    1. n the wake of the COVID-19 pandemic, it has been mandated to keep enlarged distances from others. We interviewed 136 German subjects over five weeks from the end of March to the end of April 2020 during the first wave of infections about their preferred interpersonal distance (IPD) before, during, and after the COVID-19 pandemic. In response to the pandemic, subjects adapted to distance requirements and preferred a larger IPD. This enlarged IPD was judged to persist after the crisis partially. People anticipated keeping more IPD to others even if there was no longer any risk of a SARS-CoV-2 infection. We also sampled two follow-up measurements, one in August, after the first wave had been flattened, and one in October 2020, at the beginning of the second wave. We discuss our findings in light of proxemic theory and an indicator for socio-cultural adaptation beyond the course of the pandemic.
    1. We compare patterns of sexual violence against adults (n = 317) and children (n = 224) in Kenya during the COVID-19 pandemic in order to inform sexual violence prevention and protection efforts. The data we analyse were coded from interviews conducted by human rights defenders who were assisting survivors in obtaining vital services. We found that children were more likely than adults to be attacked during the daytime, by a single perpetrator rather than multiple perpetrators, and in a private as opposed to a public location. Children were violated most often by neighbors and family members, whereas adults were equally likely to be attacked by strangers and persons known to them. On average, the children in the sample were four years younger compared to the average age reported in national samples pre-pandemic (age 12 versus 16). Survivors were more likely to be female than male. Policy recommendations are offered based on our findings.
    1. The COVID-19 pandemic is the greatest global crisis of our lifetimes and leadership has been critical to societies’ capacity to deal with it. Here effective leadership has brought people together, provided a clear perspective on what is happening and what response is needed, and mobilised the population to act in the most effective ways to bring the pandemic under control. Informed by a model of identity leadership (Haslam, Reicher & Platow, 2020), this review argues that leaders’ ability to do these things is grounded in their ability to represent and advance the shared interests of group members and to create and embed a sense of shared social identity among them (a sense of “us-ness”). For leaders, then, this sense of us-ness is the key resource that they need to marshal in order to harness the support and energy of citizens. The review discusses examples of the successes and failures of different leaders during the pandemic and organises these around five policy priorities related to the 5Rs of identity leadership: Readying, Reflecting, Representing, Realising and Reinforcing. These priorities and associated lessons are relevant not only to the management of COVID-19 but to crisis management and leadership more generally.
    1. Civil defense. Influence monitoring. Enhanced unconventional warfare capabilities. New political warfare coordination. Fight for our values at home and abroad.
    1. Physical distancing is crucial for slowing the spread of COVID-19, but the associated reduction of social interaction can be detrimental to psychological wellbeing. Here, we sought to understand whether different ways in which people connect to others might mitigate this negative impact. We examined how amount and type of social interactions and social media use would predict wellbeing during a period of physical distancing in the United Kingdom. In a 30-day diary study conducted in April-June 2020, 108 participants reported their daily social interactions and social media use, as well as their end-of-day wellbeing. Using multilevel regressions, we found that more face-to-face interactions positively predicted wellbeing, while technology-mediated communication had less consistent positive effects on wellbeing. More active and less passive social media use was associated with greater wellbeing. Our results suggest that while technology-mediated communication can improve wellbeing, face-to-face interactions are unique and important for wellbeing during physical distancing.
    1. he real Covid news gets better every day. Case numbers are falling. Hospital admissions are falling. Deaths are falling. The vaccination programme is a success beyond anyone's wildest imagination. New, effective treatments are emerging. Spring, fresh air and sunshine are almost upon us.ADVERTISEMENT{"requests":{"csi":"https://csi.gstatic.com/csi?"},"transport":{"xhrpost":false},"triggers":{"adRequestStart":{"on":"ad-request-start","request":"csi","sampleSpec":{"sampleOn":"a4a-csi-${pageViewId}","threshold":1},"selector":"amp-ad","selectionMethod":"closest","extraUrlParams":{"met.a4a":"afs_lvt.${viewerLastVisibleTime}~afs.${time}"}},"adResponseEnd":{"on":"ad-response-end","request":"csi","sampleSpec":{"sampleOn":"a4a-csi-${pageViewId}","threshold":1},"selector":"amp-ad","selectionMethod":"closest","extraUrlParams":{"met.a4a":"afe.${time}"}},"adRenderStart":{"on":"ad-render-start","request":"csi","sampleSpec":{"sampleOn":"a4a-csi-${pageViewId}","threshold":1},"selector":"amp-ad","selectionMethod":"closest","extraUrlParams":{"met.a4a":"ast.${scheduleTime}~ars_lvt.${viewerLastVisibleTime}~ars.${time}","qqid":"${qqid}"}},"adIframeLoaded":{"on":"ad-iframe-loaded","request":"csi","sampleSpec":{"sampleOn":"a4a-csi-${pageViewId}","threshold":1},"selector":"amp-ad","selectionMethod":"closest","extraUrlParams":{"met.a4a":"ail.${time}"}}},"extraUrlParams":{"s":"ampad","ctx":"2","c":"${correlator}","slotId":"${slotId}","puid":"${requestCount}~${timestamp}"}}{"transport":{"beacon":false,"xhrpost":false},"requests":{"visibility1":"https://pagead2.googlesyndication.com/pcs/activeview?xai=AKAOjss-vQjNUP78eIujxsqd1zb1s_Ieqsh2jNEjiuoMIqu2hzEWAJnJ-SvgYo4pBkZycxz5afWcGV84tyTcXKf0L_YcKTxd-oAATZSJ0qLpY4E&sig=Cg0ArKJSzMMZ9tqhK04eEAE&id=ampim&o=${elementX},${elementY}&d=${elementWidth},${elementHeight}&ss=${screenWidth},${screenHeight}&bs=${viewportWidth},${viewportHeight}&mcvt=${maxContinuousVisibleTime}&mtos=0,0,${maxContinuousVisibleTime},${maxContinuousVisibleTime},${maxContinuousVisibleTime}&tos=0,0,${totalVisibleTime},0,0&tfs=${firstSeenTime}&tls=${lastSeenTime}&g=${minVisiblePercentage}&h=${maxVisiblePercentage}&tt=${totalTime}&r=v&avms=ampa&adk=2528340120","btr1":"https://securepubads.g.doubleclick.net/pcs/view?xai=AKAOjstFzLpzkAIYMJiF0gz473squSjpvO8-0d8UuPsuSPpNYbk7ctV6pTs02zT6ZvHciTRNc7g8Mrv3OWgAoRbrfWzOApakgWCFcd6LMk6X52Dw9-gNDEXXK0JJlVKIcwHrMpsZ6JzmC3PsygLcm4wUW9tJzT9QDTASwB7QYmpDSCM3lWt2zQloZNjpwNXh0OZ2b4ZLUfHg_rSzBTwldkrwDvgH6-OFm4C4YjFA4cTA6WZwkoJv4fM4deO2dTaot6kVOMrZESQjsuP3nFbdaQaluYr6HRxVW5MG3RvkvvSCFpfbooYMyUnghtkHZSKbAlgBSvgvTgB525uN_aZMo7eNA5AGbaBIVQc1EFQiJ6Q3roqDsA&sai=AMfl-YRtdo31o6GgCTlilFM4fP_cgfjIBNtP5IKcLuWE90tU_nu9dpQy3kZio1hsEYPt2eIZNwrxKs_49m6vpYY-qnQjBiC5bsHJwJvpoLUvXqLz&sig=Cg0ArKJSzJRksUuGCjAfEAE&urlfix=1&adurl="},"triggers":{"continuousVisible":{"request":["visibility1"],"on":"visible","visibilitySpec":{"selector":"amp-ad","selectionMethod":"closest","visiblePercentageMin":50,"continuousTimeMin":1000}},"beginToRender":{"request":["btr1"],"on":"ini-load","selector":"amp-ad","selectionMethod":"closest"}}}Why, then, is there so much talk of keeping restrictions in place for the rest of the year? Why do some say that we should keep the so-called 'Rule of Six' for months to come and warn we might be wearing face masks for ever – yes, for ever – in some situations at least?
    1. People's opinions evolve over time as they interact with their friends, family, colleagues, and others. In the study of opinion dynamics on networks, one often encodes interactions between people in the form of dyadic relationships, but many social interactions in real life are polyadic (i.e., they involve three or more people). In this paper, we extend an asynchronous bounded-confidence model (BCM) on graphs, in which nodes are connected pairwise by edges, to hypergraphs. We show that our hypergraph BCM converges to consensus under a wide range of initial conditions for the opinions of the nodes. We show that, under suitable conditions, echo chambers can form on hypergraphs with community structure. We also observe that the opinions of individuals can sometimes jump from one opinion cluster to another in a single time step, a phenomenon (which we call "opinion jumping") that is not possible in standard dyadic BCMs. We also show that there is a phase transition in the convergence time on the complete hypergraph when the variance σ2\sigma^2 of the initial opinion distribution equals the confidence bound cc. Therefore, to determine the convergence properties of our hypergraph BCM when the variance and the number of hyperedges are both large, it is necessary to use analytical methods instead of relying only on Monte Carlo simulations.
    1. Many counties, particularly small counties, do not have enough paid health care workers to staff vaccination clinics for hours every day, so they rely on volunteers to squeeze in time on days off, and before and after work, to help inoculate people against the deadly virus. The people stepping up are often doctors, nurses and students who give up their free time after long hours in classrooms, medical practices, ICUs, and ERs where they have battled the virus for the past year.
    1. The Coronavirus Disease 2019 (COVID-19) pandemic has caused an increase in the use of pulse oximeters, and a recent report (Sjoding et al.External Link Disclaimer) suggests that the devices may be less accurate in people with dark skin pigmentation. The U.S. Food and Drug Administration (FDA) is informing patients and health care providers that although pulse oximetry is useful for estimating blood oxygen levels, pulse oximeters have limitations and a risk of inaccuracy under certain circumstances that should be considered. Patients with conditions such as COVID-19 who monitor their condition at home should pay attention to all signs and symptoms of their condition and communicate any concerns to their health care provider.
    1. In Great Britain, 95 per cent of people aged over 70 have had at least one dose of a coronavirus vaccine, according to a survey of 6000 people by the Office of National Statistics (ONS). Most of the remainder have been offered a vaccine and are waiting to receive it. Less than 1 per cent of people aged over 70 years said they declined the offer of a vaccine. Overall, 91 per cent of all adults surveyed said they had either been vaccinated already or would get vaccinated when offered it. These numbers are better than expected. For instance, in one UK survey done in December before vaccination began, just 72 per cent said they were willing to get vaccinated. However, the ONS survey did not include adults living in care homes or other establishments, and because of small sample sizes, the ONS says the percentage of people saying they have declined vaccination should be treated with caution.
    1. The COVID-19 pandemic has raised significant concerns regarding the effect of social disruptions on parental mental health, family well-being, and children’s adjustment. Due to the pace of the pandemic, measures of pandemic-related disruption have not been subject to rigorous empirical validation. To address this gap, a multi-national sample (United Kingdom, 76%; United States, 19%; Canada, 4%, and Australia, 1%) of 372 female caregivers and 158 male caregivers of 5-18 year-old children was recruited online. Participants completed a survey including a 25-item scale indexing disruption in finances, basic needs, personal and family welfare, career/education, household responsibilities, and family relationships related to the pandemic. An exploratory factor analysis yielded an optimal three-factor solution: factors included Income Stress (5 items related to income, debt, and job loss; loadings ranged from .57 to .91), Family Stress (7 items related to family altercations and child management; loadings from .57 to .87), and Chaos Stress (4 items related to access to supplies, crowded shopping areas, news coverage; loadings from .53 to .70). Multiple-group confirmatory factor analysis demonstrated measurement invariance of each factor across female and male caregivers, indicating that factor structure, loadings, and thresholds were equivalent across groups. Composites reflective of each factor were computed, and paired samples t-tests showed that female caregivers consistently report higher levels of COVID-19 stress related to income, family, and chaos compared to male caregivers. Finally, concurrent validity was demonstrated by significant bivariate correlations between each scale and indicators of parental and child mental health and family relationships. This demonstrates validity of the COVID-19 Family Stressor Scale for use with female and male caregivers in family-based research. The current sample was predominantly White-European. Additional sampling and validation efforts are required in order to provide adequate description of racialized and minority communities at disproportionate risk of social consequences related to the pandemic.
    1. As vaccines against COVID-19 are scarce, many countries have developed vaccination prioritization strategies focusing on ethical and epidemiological considerations. However, public acceptance of such strategies should be monitored to ensure successful implementation. In an experiment with N = 1,379 German participants, we investigated whether the public’s vaccination allocation preferences matched the prioritization strategy approved by the German government. Results revealed different allocations. While the government had top-prioritized vulnerable people (being of high age or accommodated in nursing homes for the elderly), participants deprioritized these groups and preferred exclusive allocation of the first available vaccines to medical staff and personnel caring for the elderly. Interestingly, allocation preferences did not change when participants were told how many individuals were included in each group. As differences between allocation policies and public preferences can affect trust in the government and threaten the social contract between generations, we discuss possible strategies to align vaccination prioritizations.
    1. In the midst of the Covid-19 pandemic (between 26 March and 2 April 2020), we analysed (n=1144) the social representations of the coronavirus and the differentiated perceptions according to the origins attributed to the appearance of the virus (Human vs Non-Human and Intentional vs. Unintentional) in a French population. The results show that the social representation is organized around five potentially central descriptive, anxiety-provoking and globally negative elements. But death and contagion are the only stable and structuring elements. The other elements vary according to the reason attributed to the object of fear. Depending on how individuals attribute the origin of the virus, social representations of it vary not only in terms of their content but also in terms of their structure. These results indicate how important it is to consider the perceptions that individuals share about the human (vs. non-human) and intentional (vs. unintentional) origin of an object of fear in the analysis of their representation of that object.
    1. Amidst a global pandemic, people’ survival needs become salient and the ability for people to regulate feeling and actions might be particularly relevant to protecting oneself from harm. Regulatory Focus Theory (Higgins, 1998) proposes that people pursue their goals by having a focus on prevention (i.e., motivated by security) or promotion (i.e., motivated by pleasure). Prior research indicates that people focused on prevention (vs. promotion) are more likely to engage in health-protective behaviors, including sexual health behaviors, because they perceive more threats. Extending this reasoning to the sexual activity of single people during the COVID-19 pandemic, we conducted a pre-registered longitudinal study (N = 174) examining the role of regulatory focus on people’s sexual behaviors. As hypothesized, results showed that single people who reported having a more prevention focus at the onset of the pandemic perceived greater threats caused by the pandemic two weeks later, which, in turn, predicted less frequent sexual activity and engagement in sex with fewer sexual partners the following two weeks. These effects were consistent even when controlling for promotion (i.e., pleasure motivations), personality, gender, and sexual orientation. Findings are discussed considering their implications for the sexual functioning and sexual health of single people.
    1. We investigated the effect of the COVID-19 pandemic and lockdown on optimism and meaning in life in a sample of the Netherlands Twin Register. Participants completed questions before (N=9964) and during the pandemic (N= 17464). A subsample completed both (N=6461). We applied twin models to investigate changes in the genetic architecture due to the pandemic. Around 15-20% of the sample was negatively affected by the pandemic, but the majority was stable (64-68%) or increased (15%) in optimism and meaning in life. Especially women, higher educated people, and people with poorer health experienced negative effects. Twin modelling indicated stable genetic variance and increasing person-specific environmental variance. The lower than unity genetic correlations across time (.75 and .63) suggest gene-environment interactions. Some people decrease in well-being, while others get more optimistic and consider their lives as more meaningful during the pandemic. These differences are partly explained by individual differences in genetic sensitivity.
    1. COVID-19 has infected millions of people and upended the lives of most humans on the planet. Researchers from across the psychological sciences have sought to document and investigate the impact of COVID-19 in myriad ways, causing an explosion of research that is broad in scope, varied in methods, and challenging to consolidate. Because policy and practice aimed at helping people live healthier and happier lives requires insight from robust patterns of evidence, this paper provides a rapid and thorough summary of high-quality studies published in 2020 addressing two overarching questions. First, what are the mental health consequences of living through the COVID-19 pandemic? Second, what are the neurological sequelae of contracting COVID-19? Our review of the evidence indicates that some facets of mental health suffered greatly during the early months of the pandemic (e.g., anxiety and depression increased), while other facets (life satisfaction) and correlates (social connection, loneliness) notably displayed resilience. In addition, early neurological data indicate several consequences of contracting COVID-19, both during infection and after recovery. In response to these insights, we present seven recommendations (1 urgent, 2 short-term, 4 ongoing) to support mental health and well-being during the pandemic and beyond.
    1. We frequently claim that lying is wrong, despite modeling that it is often right. The present research sheds light on this tension by unearthing systematic cases in which people believe lying is ethical in everyday communication and by proposing and testing a theory to explain these cases. Using both inductive and experimental approaches, I find that deception is perceived to be ethical, and individuals want to be deceived, when deception is perceived to prevent unnecessary harm. I identify eight implicit rules – pertaining to the targets of deception and the topic and timing of a conversation – that clarify systematic circumstances in which deception is perceived to prevent unnecessary harm, and I document the causal effect of each implicit rule on the endorsement of deception. I also explore how perceptions of unnecessary harm influence communicators’ use of deception in everyday life, above and beyond other moral concerns. This research provides insight into when and why people value honesty and paves the way for future research on when and why people embrace deception.
    1. Study Objectives: To prospectively examine changes in adolescent sleep before and during the COVID-19 pandemic in adolescents with and without ADHD. Methods: Participants were 122 adolescents (ages 15-17; 61% male; 48% with ADHD). Parents reported on adolescents’ sleep duration and difficulties initiating and maintaining sleep (DIMS); adolescents reported on sleep patterns, sleep duration, delayed sleep/wake behaviors, and daytime sleepiness before (September 2019-February 2020) and during (May-June 2020) COVID-19. Adolescents also reported on their health behaviors, COVID-19-related negative affect, and difficulties concentrating due to COVID-19. Results: Parents reported adolescents had more DIMS during COVID-19 than before COVID-19, with clinically-elevated rates increasing from 24% to 36%. Both bedtimes and waketimes shifted later during COVID-19, and adolescents reported more delayed sleep/wake behaviors. Adolescents also reported less daytime sleepiness and longer school night sleep duration during COVID-19. In considering differences between adolescents with and without ADHD, adolescents with ADHD did not experience an increase in school night sleep duration and were less likely to obtain recommended sleep duration during COVID-19. In the full sample, controlling for ADHD status, COVID-19-related sadness/loneliness was associated with increases in DIMS, and spending less time outside and more COVID-19-related worries/fears were associated with increases in delayed sleep/wake behaviors during COVID-19. Conclusions: COVID-19 had negative and positive impacts on adolescent sleep. Adolescents with ADHD did not experience the benefit of increased school night sleep duration during COVID-19 like adolescents without ADHD. Negative affect and health behaviors may be useful intervention targets for reducing negative impacts of COVID-19 for adolescent sleep.
    1. We have detected a new variant circulating in December in Manaus, Amazonas state, north Brazil, where very high attack rates have been estimated previously. The new lineage, named P.1 (descendent of B.1.1.28), contains a unique constellation of lineage defining mutations, including several mutations of known biological importance such as E484K, K417T, and N501Y. Importantly, the P.1 lineage was identified in 42% (13 out of 31) RT-PCR positive samples collected between 15 to 23 December, but it was absent in 26 publicly available genome surveillance samples collected in Manaus between March to November 2020. These findings indicate local transmission and possibly recent increase in the frequency of a new lineage from the Amazon region. The higher diversity and the earlier sampling dates of P.1. in Manaus corroborates the travel info of recently detected cases in Japan, suggesting the direction of travel was Manaus to Japan. The recent emergence of variants with multiple shared mutations in spike raises concern about convergent evolution to a new phenotype, potentially associated with an increase in transmissibility or propensity for re-infection of individuals.
    1. Just as hope for relief from the COVID-19 pandemic brightened in December, with emergency use approval for vaccines following phase 3 trials and the start of immunisation programmes, unprecedented numbers of cases, hospital admissions, and deaths have been recorded, including in countries such as Germany and Japan that were previously celebrated for their public health response. Predictions that the northern hemisphere winter would be a difficult time for control of COVID-19, as is typically the case with respiratory viral diseases, have proved to be correct. Emergence in South Africa and the UK of new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that are substantially more transmissible, has added to concerns that health services will be overwhelmed.
    1. The credibility of scientific findings and research relies on a 'common good': peer-review. The independent review and validation of work by experts is what distinguishes published scientific findings and marks them out as reliable, rigorous evidence.
    1. About 40 per cent of Hong Kongers surveyed were willing to receive a Covid-19 vaccine, a university study in the city showed on Thursday.
    1. Digital contact tracing apps have been introduced globally as an instrument to contain the COVID-19 pandemic. Yet, privacy by design impedes both the evaluation of these tools and the deployment of evidence-based interventions to stimulate uptake. We combine an online panel survey with mobile tracking data to measure the actual usage of Germany’s official contact tracing app and reveal higher uptake rates among respondents with an increased risk of severe illness, but lower rates among those with a heightened risk of exposure to COVID-19. Using a randomized intervention, we show that informative and motivational video messages have very limited effect on uptake. However, findings from a second intervention suggest that even small monetary incentives can strongly increase uptake and help make digital contact tracing a more effective tool.
    1. Yesterday on the Today programme, BBC Radio 4's flagship news programme, they included a number of stories/accounts of people obeying the lockdown rules. The idea behind this was to counter the effect whereby breaking the rules is normalised by hearing about instances of it on the news.
    1. In fall of 2019, exactly zero scientists were studying COVID‑19, because no one knew the disease existed. The coronavirus that causes it, SARS‑CoV‑2, had only recently jumped into humans and had been neither identified nor named. But by the end of March 2020, it had spread to more than 170 countries, sickened more than 750,000 people, and triggered the biggest pivot in the history of modern science. Thousands of researchers dropped whatever intellectual puzzles had previously consumed their curiosity and began working on the pandemic instead. In mere months, science became thoroughly COVID-ized.
    1. The growing body of research on interdisciplinarity has encouraged a more in depth analysis of the relations that hold among academic disciplines. In particular, the incursion of one scientific discipline into another discipline’s traditional domain, also known as scientific imperialism, has been a matter of increasing debate.
    1. London’s intensive care units are overwhelmed, and those elsewhere in the UK may soon be too. The number of Covid-19 patients arriving in ICUs far exceeds the first wave in April, and those needing life-saving treatment such as mechanical ventilation have exhausted resources. Ambulances are queueing at hospital gates, patients are being transferred hundreds of miles and oxygen supplies are running low. The most severe shortage is not in beds, but in staff. NHS England has lowered ICU nurse staffing ratios from one nurse per patient to one for every two, and hospitals in the Midlands are being told to dilute their ratios further.Clinicians are now being forced to make agonising choices about who does and who does not receive care, with consequences for the survival of patients. Research on the first wave last spring found that when ICUs reach full capacity, the chance of a patient dying is 19 per cent higher. Is this decided by a random roll of the dice, or is it based on an assessment of who is at greater risk of dying? How should clinicians decide who gets the limited resources in an overstretched ICU? These are ethical questions that should be addressed by societies through expert committees, not individual clinicians.
    1. Hospital staff are receiving insufficient support as they make agonising choices about who does and does not receive care, writes Dr Katharina Hauck. In an opinion piece for the Financial Times, Dr Hauck warns that existing guidelines in an overstretched NHS are “only partly helpful”. They avoid “the tough question of how to prioritise care with severely curtailed resources, leaving heartbreaking life-or-death decision-making to clinicians.” 
    1. The effects of the covid-19 pandemic on mental health, especially amongst children, are receiving increasing attention. What is less clear are the channels through which these effects are operating. This paper helps fill this gap by isolating the impact of school closures on children’s mental health. We exploit the way in which primary school children were invited to return to school in England in the summer term of 2020, with government advice being that all children in reception, Year 1 and Year 6 should be invited to return from 1 June, while only vulnerable children and children of key workers could attend in Years 2, 3, 4 and 5. We adopt a difference-in-differences approach with child fixed effects, comparing changes over time (before the pandemic to July 2020) between children who were and were not invited to return to school using parent reports from the Strengths and Difficulties Questionnaire (SDQ). Using reports from September 2020 – when all children had been invited to return school – we can also explore the extent to which these effects persist.
    1. YouTube has been a significant source of misleading information during previous public health crises, including the Ebola and Zika outbreaks (Li et al., 2020). In March of 2020, a search of YouTube revealed that more than one quarter of the most-viewed videos contained misinformation, whereas videos from reputable sources remained underrepresented (Li et al., 2020). An in-depth scholarly analysis of how misinformation and other attributes of the online environment, and how it challenges citizens in a democracy can be found in Kozyreva et al. (2020). A detailed report on the overarching relationship between technology and democracy that was prepared for the European Commission can be found here. A quantitative analysis of the COVID-19 “infodemic” has shown that unreliable information predominated online before infections started rising in February and March 2020, but was then replaced by reliable information and content shifted towards more reliable sources (Gallotti et al., 2020).Unfortunately, misinformation about COVID-19 and COVID-19 vaccinations is sometimes also spread for political reasons. We explore this aspect in a separate page on the politics of COVID-19 vaccination.
    1. The paper investigates the influence of ideology on trust in scientists. We assume that during a pandemic, ideology is linked to levels of trust in scientists, such that those espousing left- (vs. right-) wing beliefs place more trust in the scientific profession. We posit that the negative perception of scientists, a feature of right-wing narratives in the country of study, underlies this effect. Additionally, we argue that ideology has an indirect impact, via levels of trust in scientists, on beliefs and attitudes towards vaccines and vaccine policy. To test these hypotheses, we conducted three studies (total N = 1155): one pre-pandemic study and two studies during a pandemic. The results confirm the hypotheses; however, we observed varied effects at the outset of the pandemic versus later stages. The findings contribute to the ongoing discussion around the ideological underpinnings of trust in scientists and carry implications for public health measures.
    1. The management of the COVID-19 pandemic critically hinges on the approval of safe and effective vaccines but, equally importantly, on high willingness among lay people to use vaccines when approved. To facilitate vaccination willingness via effective health communication, it is key to understand both levels of skepticism towards an approved COVID-19 vaccine and the demographic, psychological and political sources of this skepticism. To this end, we examine the levels and predictors of willingness to use an approved COVID-19 vaccine in large, representative surveys from eight Western democracies that differ both politically and in terms of the severity of the pandemic: Denmark, France, Germany, Hungary, Sweden, Italy, United Kingdom, and United States (total N = 9,889). The data reveal large variation in vaccination willingness, both across and within countries ranging from 79 % in Denmark to 38 % in Hungary. Thus, most national levels fall below current best estimates for the required threshold for reaching herd immunity. Across national and demographic groups, the analyses demonstrate that a lack of vaccination willingness is associated with low levels of trust in authorities, conspiracy-related beliefs and a lack of concern about COVID-19. These factors also account for cross-national levels in vaccine willingness.
    1. Little is known about the interests of the doctors, scientists, and academics on whose advice the UK government relies to manage the pandemic. Attempts to discover more are frequently thwarted, finds Paul D Thacker
    1. Peer-review is a necessary and essential quality control step for scientific publications but lacks proper incentives. Indeed, the process, which is very costly in terms of time and intellectual investment, not only is not remunerated by the journals but is also not openly recognized by the academic community as a relevant scientific output for a researcher. Therefore, scientific dissemination is affected in timeliness, quality, and fairness. Here, to solve this issue, we propose a blockchain-based incentive system that rewards scientists for peer-reviewing other scientists' work and that builds up trust and reputation. We designed a privacy-oriented protocol of smart contracts called Ants-Review that allows authors to issue a bounty for open anonymous peer-reviews on Ethereum. If requirements are met, peer-reviews will be accepted and paid by the approver proportionally to their assessed quality. To promote ethical behavior and inclusiveness the system implements a gamified mechanism that allows the whole community to evaluate the peer-reviews and vote for the best ones.
    1. People across the world have responded to the pandemic by mobilising and organising to support their communities, setting up mutual aid groups to provide practical, financial, and social support. Mutual aid means short-term ‘crisis response’ for some, while for other groups, it is a chance to radically restructure society, and what it means to be a member of that society. We applied a social representations lens to examine the ways in which citizenship was understood and performed by members of UK Covid-19 mutual aid groups. Interviews were conducted with 29 members of these groups. A reflexive thematic analysis developed three conceptualisations of citizenship: (1) human rights-based citizenship, untied to concerns around ‘deservingness’ or legal status; (2) neoliberal citizenship, to which participants oriented pragmatically in order to claim their group’s legitimacy at the same time as they rejected its individualism; and (3) resistant citizenship, which captured the tension between working within/with existing political structures, or working outside/against them. Findings are discussed in relation to previous theoretical and empirical work and practical implications for policy makers and local government are set out.
    1. What we know, and what we don’tThe UK’s £100bn “Operation Moonshot” to roll out mass testing for covid-19 to cities and universities around the country raises two key questions. How infectious are people who test positive but have no symptoms? And, what is their contribution to transmission of live virus?
    1. About 10% of the City of Pittsburgh’s workforce is off work because they are quarantining for possible covid-19 exposure, the city announced Wednesday. That amounts to about 330 of the city’s 3,300-person workforce. A smaller but unspecified number of workers are off because they’ve tested positive for covid.
    1. Objective: To investigate the perception and adherence to mitigation measures during the first wave of the COVID-19 epidemic in Slovenia by examining their trends across several sociodemographic categories and personality dimensions. Methods: Descriptive and correlative analyses were used to examine which sociodemographic and personality factors were associated with participants’ attitudes and adherence to measures. Results: More than 90% of participants considered the following four measures as important and practiced them always/often: keeping a safe interpersonal distance, regular and thorough hand washing/disinfection, adherence to the rules of cough hygiene, and regular indoor ventilation. The strongest predictors of confidence in the preventive measures and their implementation were the participants’ concern of infection and concern of infecting their loved ones, followed by gender (with higher measure adherence in women) and age (with higher measure adherence in participants under 30 and over 60 years of age). Education, settlement size, field and type of employment, household type, own medical problems, and the age and health of the participants’ loved ones had a smaller influence on the perceived importance and implementation of guidelines. Adherence to measures was positively related to the participants’ score in conscientiousness and, in lesser extent, openness. Agreeableness, energy, and emotional stability correlated positively with adherence to basic guidelines. Conclusions: Study provides information useful for developing and adapting future public health policies and interventions in Slovenia.
    1. Everyone has heard about doctors and nurses catching Covid-19 but some of the worst affected hospital staff have been cleaners and porters. Dr John Wright of Bradford Royal Infirmary tells the story of a cleaner who became ill, and is now stricken with guilt for taking the virus home
    1. New research found ‘autoantibodies’ similar to those in lupus and rheumatoid arthritis patients. But patients may also benefit from treatments for those autoimmune diseases.
    1. The theory underlying network science predates the internet. But in 2020, it became essential to understanding our interconnected world.
    1. “How can we follow the science when scientists haven't the foggiest.” “‘Big mouth’ scientists losing trust of Ministers.” Headlines such as these are increasingly common in UK newspapers. Scientists are no longer seen as providing impartial, independent advice to government. They are seen as being responsible for crashing economies, driving up unemployment, and ruining livelihoods. Chris Whitty, England's Chief Medical Officer, and Patrick Vallance, Chief Scientific Adviser, have received the sharpest criticism. But attacks are now spreading to members of the scientific committees that advise government. They stand accused of leaking documents to journalists, promoting their own personal views, and collaborating with opposition political parties. The argument is that if a scientist is a member of a group advising ministers, they have chosen to be part of the government team and must abide by a rule of collective responsibility. The breakdown of trust between scientists and politicians is so great that senior figures in public health are being blocked from speaking to reporters, even on subjects unrelated to COVID-19.
    1. Given the size and scope of the Russian propaganda campaign that targeted the U.S. electorate in 2016, it is critical to understand both the impact of that campaign and the mechanisms that can reduce the impact of future campaigns. This report, the third in a four-part series, describes a study conducted by RAND researchers to assess how people react to and engage with Russia's online propaganda and to determine whether the negative effects of that engagement can be mitigated by brief media literacy advisories or by labeling the source of the propaganda. Russia targets the extremes on both sides of the political divide, and a short media literacy video and labeling intervention were both shown to reduce willingness among particular categories of participants (defined by news consumption habits) to "like" the propaganda.
    1. During a time of crisis Americans turn their attention to the news media for critical information about what to expect, who is affected, and how to behave. Throughout the COVID-19 crisis, public safety experts warned that the consequences of a misinformed population would be particularly dire due to the serious nature of the threat and necessity of severe individual collective action to keep the population safe. Thus, those elites who possess the power to set the agenda of the conversation bear a huge responsibility for the general welfare. Among the various agenda-setting mechanisms available to the president is daily press conferences which provide a unique opportunity to leverage public exposure, accelerated by the state of crisis. Yet, mainstream media's daily viewership is many times larger than the president's press conference and we explore their narratives surrounding the COVID-19 pandemic through automated text analysis of complete transcripts of national cable, network, and local news. Of particular importance, we characterize the differences in which topics were covered and how they were covered by various cable media sources. Our analysis reveals polarized narratives around blame, racial and economic disparities, and scientific conclusions about COVID-19. The media is influenced by the president's agenda, even for cable news channels that are consumed by audiences that typically do not support him, but we found strong evidence that the media's choices mediate, and ultimately dominate, the agenda-setting abilities of the president's daily press conferences.
    1. Thinking critically is not a superpower. But the University of Alberta is offering a boost to critical thinking about science with a free online course — how to tell the difference between sound scientific studies and pseudoscience.
    1. Academic union seeks legal battle over government’s decision to ignore expert advice to move all non-essential teaching online
    1. Summary of findings from the publication, Li Y et al. The temporal association of introducing and lifting non-pharmaceutical interventions with the time-varying reproduction number (R) of SARS-CoV-2: a modelling study across 131 countries. Lancet Infectious Diseases 2020.
    1. Non-pharmaceutical interventions (NPIs) were implemented by many countries to reduce the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of COVID-19. A resurgence in COVID-19 cases has been reported in some countries that lifted some of these NPIs. We aimed to understand the association of introducing and lifting NPIs with the level of transmission of SARS-CoV-2, as measured by the time-varying reproduction number (R), from a broad perspective across 131 countries.
    1. Of all the changes brought by a pandemic and the responses to it this year, many seem as if they were waiting to happen, given a hard nudge.
    1. Injections of antibodies might prevent mild COVID-19 from becoming severe, but the treatments are expensive and difficult to make.
    1. The COVID-19 pandemic has provided a unique opportunity to think about the kind of future we want. TIME partnered with the World Economic Forum to ask leading thinkers to share ideas for how to transform the way we live and work.
    1. Even though conspiracy theorieslook like they are based on arguments, people’sreasons for believingin them tend to be psychological. For example, they may feel the needfor certainty, control, belonging ormeaning. This is why facts alone can’t usuallyalter someone’s beliefs. You also need to address the feelings that push someone towards a conspiracy theory.
    1. Preprints have been growing in popularity and visibility across many disciplines and communities — all the more so during the COVID19 pandemic, with rapid publication of early research on everything from vaccine development to economic impacts. While preprints have been widely adopted in some disciplines, there are still concerns about their quality and reliability, especially when they can be readily accessed by policy-makers and the public who may not yet fully understand their limitiations. This session brings together three experts — from Africa, Latin America, and the US — to discuss the challenges and opportunities of preprints for researchers and non-researchers alike.
    1. Today EMA has released its first safety update on a COVID-19 vaccine — Comirnaty. It concludes that safety data collected on Comirnaty use in vaccination campaigns is consistent with the known safety profile of the vaccine, and no new side effects were identified.
    1. The prevailing approach to protecting political speech on the major digital platforms has been to pressure the companies to self-regulate by creating, for instance, oversight boards of outside experts. But leaving these momentous decisions in the hands of private companies is not a long-term solution; they have neither the legitimacy nor the capacity to make such decisions in the public interest. The core issue is the oversize power of Twitter, Facebook and Google in controlling political discourse. One measure with some congressional support is to repeal or change Section 230 of the Communications Decency Act, which limits the liability of platforms for the content they carry. But reform could hurt small companies more than the established giants, who can more easily develop algorithms and hire personnel to filter out problematic content.
    1. Introduction:To mitigate the spread of the pandemic coronavirus infection (COVID-19), governments across the world have adopted “lockdowns” which have confined many individuals to their homes. This disrupts normal life routines, elements of which are important circadian cues. The pandemic is also associated with new stressors, altered roles, and uncertainties about health and economic security, which are also likely to affect sleep. The current study is an online survey of sleep experience, routines, physical activity, and symptoms of anxiety and depression, to study the alterations associated with the lockdown.Materials and Methods:The survey was conducted in early May 2020 using a questionnaire circulated through social media platforms. Questions related to demographic characteristics, current and previous sleep schedules, routine, and working patterns. Insomnia (Insomnia Severity Index - 4), Stress (Perceived Stress Scale - 4), anxiety and depressive symptoms (Patient Health Questionnaire - 4) and physical activity (International Physical Activities Questionnaire) were assessed using standardized instruments.Results:A total of 958 valid responses were received. Compared to the prelockdown period, there was a shift to a later bedtime and waking time, with a reduction in night-time sleep and an increase in day-time napping. These effects were visible across occupational groups, but mostly affected working individuals except health professionals. Sleep quality deteriorated across groups. Reductions in sleep duration were associated with depressive symptoms.Conclusions:The COVID-19 lockdown is associated with changes in sleep schedule and in the quantity and quality of night-time sleep. Although these changes are associated with elevated rates of emotional symptoms, it is unclear from these cross-sectional results, whether sleep deterioration produces psychological distress, or vice versa.
    1. Sleep health has multiple dimensions including duration, regularity, timing, and quality [1, 2, 3, 4]. The Coronavirus 2019 (COVID-19) outbreak led to Stay-at-Home orders and Social Distancing Requirements in countries throughout the world to limit the spread of COVID-19. We investigated sleep behaviors prior to and during Stay-at-Home orders in 139 university students (aged 22.2 ± 1.7 years old [±SD]) while respectively taking the same classes in-person and remotely. During Stay-at-Home, nightly time in bed devoted to sleep (TIB, a proxy for sleep duration with regard to public health recommendations [5]) increased by ∼30 min during weekdays and by ∼24 mins on weekends and regularity of sleep timing improved by ∼12 min. Sleep timing became later by ∼50 min during weekdays and ∼25 min on weekends, and thus the difference between weekend and weekday sleep timing decreased — hence reducing the amount of social jetlag [6,7]. Further, we find individual differences in the change of TIB devoted to sleep such that students with shorter TIB at baseline before the first COVID-19 cases emerged locally had larger increases in weekday and weekend TIB during Stay-at-Home. The percentage of participants that reported 7 h or more sleep per night, the minimum recommended sleep duration for adults to maintain health [5] — including immune health — increased from 84% to 92% for weekdays during Stay-at-Home versus baseline. Understanding the factors underlying such changes in sleep health behaviors could help inform public health recommendations with the goal of improving sleep health during and following the Stay-at-Home orders of the COVID-19 pandemic.
    1. The 2019 novel SARS-CoV2 disease causing COVID-19 has had a devastating impact on the world, and those with pain conditions may be at heightened risk for these negative consequences. Given COVID-19 limitations, including social distancing and stay-at-home orders, pain is likely largely going untreated, leading to greater pain and associated consequences. Mental health symptoms, which have been found to be elevated due to COVID-19, may contribute to elevated pain experience, but little work has examined how COVID-19-specific mental health factors may be associated with pain. Therefore, the current study examined (1) how COVID-19-specific psychological factors and general mental health symptoms differ between those with pain and without, and (2) among those with pain, which psychological factors were most strongly associated with pain experience. Results from a national (U.S. based) online sample of 174 adults (42.5% female, M age = 37.80 years, SD = 11.30, 88 with pain) collected between April and May 2020 indicated that, compared to those individuals reporting no pain, those with pain reported significantly higher values on all variables. Additionally, COVID-19 fear and sleep problems were associated with pain intensity, and for pain-related interference, fear, sleep problems, and depression were significantly associated. These results highlight the potential importance of COVID-19-specific psychological factors in pain experience.
    1. COVID-19 vaccination programs have been initiated in several countries to control SARS-CoV-2 transmission and return to a pre-pandemic lifestyle. However, understanding when non-pharmaceutical interventions (NPIs) can be lifted as vaccination builds up and how to update priority groups for vaccination in real-time remain key questions for policy makers. To address these questions, we built a data-driven model of SARS-CoV-2 transmission for China. We estimated that, to prevent local outbreaks to escalate to major widespread epidemics, stringent NPIs need to remain in place at least one year after the start of vaccination. Should NPIs be capable to keep the reproduction number (Rt) around 1.3, a vaccination program could reduce up to 99% of COVID-19 burden and bring Rt below the epidemic threshold in about 9 months. Maintaining strict NPIs throughout 2021 is of paramount importance to reduce COVID-19 burden while vaccines are distributed to the population, especially in large populations with little natural immunity.
    1. Background. The coronavirus (COVID-19) pandemic and the social distancing protocols used to impede the spread of the virus may have severe mental health consequences. The purpose of this study was to investigate the network of components of pandemic-related negative psychological states (i.e., fear of infection, financial worries, loneliness) and symptoms of major depressive disorder (MDD) and generalized anxiety disorder (GAD). Methods. Data from 10,061 Norwegian adults recruited through an online survey during a period of strict social distancing protocols were analyzed employing a cross-sectional Gaussian Graphical Model. Results. Of the infection fears, fear of being infected, fear of dying from the coronavirus and fear of significant others dying from it had notable connections to the GAD symptoms anxiety and/or fear of awful events. The financial worry component worry about personal economy was connected to the MDD symptom sleep problems and to the GAD symptom generalized worry. Each of the loneliness components was connected to a specific MDD symptom. Anhedonia, depressed mood and worthlessness had the highest strength centrality among the MDD symptoms; generalized worry, uncontrollability of worry, and trouble relaxing among the GAD symptoms; fear of dying from the virus among the fear of infection components; and feeling isolated among the loneliness components. A community analysis identified separate clusters for MDD and GAD as well as a cluster cutting across the two disorders. Conclusions. Particular components of the pandemic-related distressing states of fear of infection and loneliness seem to be associated with specific symptoms of MDD and GAD.
    1. Objective: Estimate the prevalence of generalized anxiety disorder (GAD) from April to June 2020. Methods: Repeated cross-sections design based in the ENCOVID-19 –a series of monthly mobile surveys with representative samples of Mexico (N= 833-1,674). The questionnaire includes the GAD-2 scale, and, in July, the GAD-7 scale was added; we examined its internal validity with confirmatory factor analysis and its concurrent validity with sociodemographic variables. Using GAD-7 as criterion, we analyzed the predictive validity of the GAD-2. We estimated the monthly prevalence with the GAD-2. Results: The GAD-7 and the GAD-2 are reliable and valid. The GAD-2 has a sensitivity of 0.87 and a specificity of 0.90. The monthly prevalence remains high and stable, between 30.7 and 32.6%. GAD concentrated in women, unemployed and persons with low socioeconomic status. Conclusions: GAD is a public health problem that worsened during the COVID-19 pandemic.
    1. Why proposals to largely let the virus run its course—embraced by Donald Trump’s administration and others—are a false promise
    1. Objective. The outbreak of the 2019 coronavirus disease (COVID-19) was an unprecedented global public health emergency with a significant psychological toll. This study aimed to understand how specific COVID-19 related stressors contributed to Chinese parents’ fear induction practices, and how these practices, in turn, contributed to their children’s disease prevention practices during the outbreak and depressive symptoms after the outbreak. Method. Parents (N=240, Mage=38.50 years, 75% mothers) with elementary-school-aged children (Mage=9.48 years, 46% girls) in Wenzhou, one of the most impacted cities in China, reported on the presence of confirmed or suspected cases in their communities, their frequencies of consuming COVID-19-related information, fear induction practices, and their children’s trait anxiety and disease prevention practices during the outbreak (January 28 to 30, 2020). Child-reported depressive symptoms were collected between March 7 and 11, 2020, during which there were very few remaining cases and no new confirmed cases or deaths. Results. Parents’ higher frequency of virus-related information consumption but not the presence of community infection was associated with their engagement in more fear induction practices, which was in turn associated with children’s greater engagement in prevention practices during the outbreak, but more post-quarantine depressive symptoms. Child trait anxiety exacerbated the association between parent fear induction and child depressive symptoms. Conclusion. Using fear induction parenting may promote children’s willingness to cooperate and participate in disease prevention practices during the crisis but at the cost of children’s long-term mental health.
    1. Background: The fundamental challenges of the COVID-19 pandemic may have lasting negative effects on the quality of mental health worldwide. Resilience is considered an important protective factor in reducing the risk of psychopathology in the face of various adverse events, such as the ongoing health crisis. The aims of the current study were to: (1) evaluate the predictive utility of resilience in accounting for positive and negative moods, substance use, depression and anxiety; and (2) compare negative and positive moods experienced before the pandemic to emotions reported during the first wave of the COVID-19 pandemic in Bulgaria, when the country still had low prevalence of infections and fatalities. Methods: 179 Bulgarian participants completed the international online Minnesota Global Survey on Stress and Resilience in the Face of the Novel Coronavirus (COVID-19), which included measures of resilience, depression and anxiety, substance use, positive and negative moods experienced both before and during the COVID-19 outbreak. Results: Resilience predicted higher levels of positive affect and lower anxiety, depression, and negative mood during the first wave of the COVID-19 outbreak in Bulgaria. A significant increase was found in negative mood and a corresponding decrease in positive mood in the time since COVID-19 began spreading compared to before the pandemic. Conclusions: Results suggest that the initial wave of the COVID-19 crisis impacted individuals’ well-being, even in countries with relatively low prevalence of COVID-19 and associated fatalities. In this challenging global setting, resilience may serve as a buffer against negative emotional states and psychological distress.
    1. Researchers are studying the sensory impact of the coronavirus, how long it lasts and what can be done to treat it.
    1. t’s hard to know how many patients we’ve lost. On a regular ward, if there’s a death, you know about it. In our intensive care unit, we’re supposed to have around 30 beds, but coronavirus has forced us to increase our capacity to more than 80, so I have no idea what’s going on around me. I can also hear cardiac arrest bells from another unit, but I don’t know what proportion of the patients live or die.
    1. SARS-CoV-2 501Y.V2, a novel lineage of the coronavirus causing COVID-19, contains multiple mutations within two immunodominant domains of the spike protein. Here we show that this lineage exhibits complete escape from three classes of therapeutically relevant monoclonal antibodies. Furthermore 501Y.V2 shows substantial or complete escape from neutralizing antibodies in COVID-19 convalescent plasma. These data highlight the prospect of reinfection with antigenically distinct variants and may foreshadow reduced efficacy of current spike-based vaccines.
    1. The Covid-19 pandemic has caused untold disruption and enhanced mortality rates around the world. Understanding the mechanisms for transmission of SARS-CoV-2 is key to preventing further spread but there is confusion over the meaning of “airborne” whenever transmission is discussed. Scientific ambivalence originates from evidence published many years ago, which has generated mythological beliefs that obscure current thinking. This article gathers together and explores some of the most commonly held dogmas on airborne transmission in order to stimulate revision of the science in the light of current evidence. Six ‘myths’ are presented, explained, and ultimately refuted on the basis of recently published papers and expert opinion from previous work related to similar viruses. There is little doubt that SARS-CoV-2 is transmitted via a range of airborne particle sizes subject to all the usual ventilation parameters and human behaviour. Experts from specialties encompassing aerosol studies, ventilation, engineering, physics, virology and clinical medicine have joined together to present this review, in order to consolidate the evidence for airborne transmission mechanisms and offer justification for modern strategies for prevention and control of Covid-19 in healthcare and community.
    1. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread rapidly in Manaus, the capital of Amazonas state in northern Brazil. The attack rate there is an estimate of the final size of the largely unmitigated epidemic that occurred in Manaus. We use a convenience sample of blood donors to show that by June 2020, 1 month after the epidemic peak in Manaus, 44% of the population had detectable immunoglobulin G (IgG) antibodies. Correcting for cases without a detectable antibody response and for antibody waning, we estimate a 66% attack rate in June, rising to 76% in October. This is higher than in São Paulo, in southeastern Brazil, where the estimated attack rate in October was 29%. These results confirm that when poorly controlled, COVID-19 can infect a large proportion of the population, causing high mortality.
    1. The collapse of economic activity in 2020 from COVID-19 has been immense. An important question is how much of that collapse resulted from government-imposed restrictions versus people voluntarily choosing to stay home to avoid infection. This paper examines the drivers of the economic slowdown using cellular phone records data on customer visits to more than 2.25 million individual businesses across 110 different industries. Comparing consumer behavior over the crisis within the same commuting zones but across state and county boundaries with different policy regimes suggests that legal shutdown orders account for only a modest share of the massive changes to consumer behavior (and that tracking county-level policy conditions is significantly more accurate than using state-level policies alone). While overall consumer traffic fell by 60 percentage points, legal restrictions explain only 7 percentage points of this. Individual choices were far more important and seem tied to fears of infection. Traffic started dropping before the legal orders were in place; was highly influenced by the number of COVID deaths reported in the county; and showed a clear shift by consumers away from busier, more crowded stores toward smaller, less busy stores in the same industry. States that repealed their shutdown orders saw symmetric, modest recoveries in consumer visits, further supporting the small estimated effect of policy. Although the shutdown orders had little aggregate impact, they did have a significant effect in reallocating consumer visits away from “nonessential” to “essential” businesses and from restaurants and bars toward groceries and other food sellers.
    1. Support for Sweden’s government and public confidence in authorities’ ability to handle the coronavirus crisis are sliding as the country’s anti-lockdown approach continues to be tested by mounting numbers of deaths and new cases.
    1. Causal inference requires theory and prior knowledge to structure analyses, and is not usually thought of as an arena for the application of prediction modelling. However, contemporary causal inference methods, premised on counterfactual or potential outcomes approaches, often include processing steps before the final estimation step. The purposes of this paper are: (i) to overview the recent emergence of prediction underpinning steps in contemporary causal inference methods as a useful perspective on contemporary causal inference methods, and (ii) explore the role of machine learning (as one approach to ‘best prediction’) in causal inference. Causal inference methods covered include propensity scores, inverse probability of treatment weights (IPTWs), G computation and targeted maximum likelihood estimation (TMLE). Machine learning has been used more for propensity scores and TMLE, and there is potential for increased use in G computation and estimation of IPTWs.
    1. Nonpharmaceutical interventions (NPIs) have been employed to reduce the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), yet these measures are already having similar effects on other directly transmitted, endemic diseases. Disruptions to the seasonal transmission patterns of these diseases may have consequences for the timing and severity of future outbreaks. Here we consider the implications of SARS-CoV-2 NPIs for two endemic infections circulating in the United States of America: respiratory syncytial virus (RSV) and seasonal influenza. Using laboratory surveillance data from 2020, we estimate that RSV transmission declined by at least 20% in the United States at the start of the NPI period. We simulate future trajectories of both RSV and influenza, using an epidemic model. As susceptibility increases over the NPI period, we find that substantial outbreaks of RSV may occur in future years, with peak outbreaks likely occurring in the winter of 2021–2022. Longer NPIs, in general, lead to larger future outbreaks although they may display complex interactions with baseline seasonality. Results for influenza broadly echo this picture, but are more uncertain; future outbreaks are likely dependent on the transmissibility and evolutionary dynamics of circulating strains.
    1. The U.S. Census Bureau’s Small Business Pulse Survey (SBPS) started asking businesses in April of last year when they expect to return to normal levels of operations, a crucial indication of how they are adapting to the pandemic, social distancing, and other public health strategies.
    1. Patients’ socioeconomic circumstances should be routinely documented in their healthcare record, say Andrew Moscrop and colleaguesHealth inequities are worsening across Britain. Data from the Office for National Statistics (ONS) show that men in England’s most deprived areas die almost a decade earlier than those living in affluent neighbourhoods.1 For women, life expectancy is falling in deprived areas. During the coronavirus pandemic, the strong emerging relation between covid-19 death rates and area deprivation reported by ONS2 and Public Health England3 has shown the exacerbation of existing inequities and highlighted the need for more comprehensive datasets in order to understand and reduce them.
    1. The current research examined whether men’s hostile sexism was a risk factor for family-based aggression during a nationwide COVID-19 lockdown in which families were confined to the home for 5 weeks. Parents who had reported on their sexist attitudes and aggressive behavior toward intimate partners and children prior to the COVID-19 pandemic completed assessments of aggressive behavior toward their partners and children during the lockdown (N = 362 parents of which 310 were drawn from the same family). Accounting for pre-lockdown levels of aggression, men who more strongly endorsed hostile sexism reported greater aggressive behavior toward their intimate partners and their children during the lockdown. The contextual factors that help explain these longitudinal associations differed across targets of family-based aggression. Men’s hostile sexism predicted greater aggression toward intimate partners when men experienced low power during couples’ interactions, whereas men’s hostile sexism predicted greater aggressive parenting when men reported lower partner-child relationship quality. Novel effects also emerged for benevolent sexism. Men’s higher benevolent sexism predicted lower aggressive parenting, and women’s higher benevolent sexism predicted greater aggressive behavior toward partners, irrespective of power and relationship quality. The current study provides the first longitudinal demonstration that men’s hostile sexism predicts residual changes in aggression toward both intimate partners and children. Such aggressive behavior will intensify the health, well-being, and developmental costs of the pandemic, highlighting the importance of targeting power-related gender role beliefs when screening for aggression risk and delivering therapeutic and education interventions as families face the unprecedented challenges of COVID-19.
    1. There is a widespread belief that the COVID-19 pandemic has increased global income inequality, reducing per capita incomes by more in poor countries than in rich. This supposition is reasonable but false. Rich countries have experienced more deaths per head than have poor countries; their better health systems, higher incomes, more capable governmentsand better preparednessnotwithstanding. The US did worse than some rich countries, but better than severalothers.Countries with more deaths saw larger declines in income. There wasthus not only no trade-off between lives and income; fewerdeaths meant more income. As a result, per capita incomes fell by more in higher-income countries. Country by country, international income inequality decreased.When countries are weightedby population, international income inequality increased, not because the poorest countries diverged from the richest countries, but because China—no longer a poor country—had few deaths and positive economic growth, pullingit away frompoorcountries. That these findingsare aresult of the pandemic is supportedby comparing global inequality using IMF forecastsin October 2019 and October 2020.
    1. Specialization is a hallmark of humans. Specialization in the real world (with imperfectly sorted partners, imperfectly calibrated supply and demand, and high failure risk) requires redundancy in relationships, which prevents specialists from going hungry when some of their partners fail to capture highly variable food items and derive the most value when dividing surplus harvests. The burgeoning field of multilayer network analysis offers tools to test for the effect of redundant relationships in food sharing networks on hunger. We derive measures that include progressively more network structure: measures without any network structure, those that only include information about individuals, and those that include all information about individuals and domains. We test for the effects of these measures in a sample of horticulturalists living in the savannahs of the Guyana Shield, a nutritionally precarious environment. Having redundant relationships is associated with a lower incidence of reported skipped meals. This provides evidence that redundancy in food sharing networks may mitigate risk associated with the foraging strategies necessary to support a large-brained, generalist omnivore. This result has consequences for broader debates in the field of human evolution such as why humans live in groups with low relatedness.
    1. Schools operating in person have seen scant transmission of the coronavirus, particularly when masks and distancing are employed, but some indoor athletics have led to infections and should be curtailed if schools want to operate safely, researchers from the Centers for Disease Control and Prevention concluded in papers published Tuesday.
    1. In almost two decades working in nursing homes, I’ve never been through a time as dire as last spring. Facilities like mine, in the greater Boston area, were working with minimal to no protective gear, very little infection-control training, limited laboratory services and constantly changing public-health guidelines. Residents with covid-19 deteriorated so quickly that they’d crash right in front of me, before we even got their test results.Support our journalism. Subscribe today.arrow-right
    1. The year 2020 will be remembered for two events of global significance: the COVID-19 pandemic and 2020 U.S. Presidential Election. In this chapter, we summarize recent studies using large public Twitter data sets on these issues. We have three primary objectives. First, we delineate epistemological and practical considerations when combining the traditions of computational research and social science research. A sensible balance should be struck when the stakes are high between advancing social theory and concrete, timely reporting of ongoing events. We additionally comment on the computational challenges of gleaning insight from large amounts of social media data. Second, we characterize the role of social bots in social media manipulation around the discourse on the COVID-19 pandemic and 2020 U.S. Presidential Election. Third, we compare results from 2020 to prior years to note that, although bot accounts still contribute to the emergence of echo-chambers, there is a transition from state-sponsored campaigns to domestically emergent sources of distortion. Furthermore, issues of public health can be confounded by political orientation, especially from localized communities of actors who spread misinformation. We conclude that automation and social media manipulation pose issues to a healthy and democratic discourse, precisely because they distort representation of pluralism within the public sphere.
    1. The COVID-19 pandemic reached staggering new peaks during an ongoing global resurgence at the end of 2020. Although public health guidelines initially helped to slow the spread of disease, widespread pandemic fatigue and prolonged harm to financial stability and mental wellbeing have contributed to this resurgence. In this late stage of the pandemic, it is clear that new interventions are needed to support long-term behavior change. Here, we examined subjective perceived risk about COVID-19, and the relationship between perceived risk and engagement in risky behaviors. In Study 1 (N = 303), we found that subjective perceived risk is inaccurate but predicts compliance with public health guidelines. In Study 2 (N = 760), we developed a multi-faceted intervention designed to realign perceived risk with actual risk. Participants completed one of three variants of an episodic simulation task; we expected that imagining a COVID-related scenario would increase the salience of risk information and enhance behavior change. Immediately following the episodic simulation, participants completed a risk estimation task with personalized feedback about local risk levels. We found that information prediction error, a measure of surprise, drove beneficial change in perceived risk and willingness to engage in risky activities. Imagining a COVID-related scenario beforehand enhanced the effect of prediction error on learning. Importantly, our intervention produced lasting effects that persisted after a 1-3 week delay. Overall, we describe a fast and feasible online intervention that effectively changed beliefs and intentions about risky behaviors.
    1. LONDON (Reuters) - British drugmaker AstraZeneca said on Saturday it believed its COVID-19 vaccine developed with the University of Oxford could protect against severe disease caused by the South African variant of the virus.
    1. This paper reviews the transformation of the academy by online technology and the development of what has been termed 'digital scholars.' A particular focus is on how such technologies have facilitated academic communication and collaboration. Several online collaborative academic projects are reviewed. It is suggested one component of online 'academic collaboratives' (collaborative online communities of scholars) could be the development of massively collaborative online textbooks that can also serve as a current overview of a discipline. It is proposed that it could utilize peer review processes similar to peer reviewed academic journals. The issues of how scholars can be given academic credit for their contributions to an academic collaborative is discussed. Part 2 of this paper will review the development and operation of an online academic collaborative in the field of evolutionary psychology.
    1. Background: A new variant of SARS-CoV-2, B.1.1.7, emerged as the dominant cause of COVID-19infection in the United Kingdom from November 2020 with a transmission advantage over the previous variants of the virus. Here we report efficacy of the adenoviral vector vaccine, ChAdOx1 nCoV-19, against this variant in comparison with non-B.1.1.7 lineages.Methods: Volunteers enrolled in phase II/III vaccine efficacy studies in the United Kingdom and randomised 1:1 to receive ChAdOx1 nCoV-19 or a MenACWY control vaccine, providedupper airway swabs every week during the trial and also if they developed possible symptomatic COVID-19 infection. Swabs were tested by nucleic acid amplification test (NAAT) for SARS-CoV-2, and positive samples were sequenced through the COVID-19Genomics UK consortium (COG UK). NAAT data were used to assess the duration ofdetectable viral RNA in diagnostic specimens and the viral load. Anti-spike IgG wasmeasured by ELISA at baseline, 14 and 28 days after prime and 28 days after boostervaccination. Neutralising antibody responses were measured using a live virus neutralisation assay against the B.1.1.7 and Victoria lineages of the virus. The efficacy analysis included symptomatic COVID-19 in seronegative participants with a NAAT positive swab more than 14 days after a second dose of vaccine. Participants were analysed according to treatment received, with data cut-off on Jan 14, 2021. Vaccine efficacy was calculated as 1 − relative risk derived from a robust Poisson regression model. This study is ongoing and is registered with ClinicalTrials.gov NCT04400838 and ISRCTN 15281137.5Findings: Between 1st October 2020 and 14th January 2021, 499 participants developed Covid-19infection. 1524 NAAT positive nose/throat swabs were collected from these participants during the trial. Of these, 323 swabs from 256 participants were successfully sequenced.ChAdOx1 nCoV-19 recipients had a significantly lower viral load as represented byminimum PCR Ct value (p<0.0001) and were NAAT positive for a shorter time (p<0.0001) than participants who received the control vaccine. Virus neutralisation activity by vaccineinduced antibodies was 9-fold lower against the B.1.1.7 variant than against a canonical non B.1.1.7 lineage. Vaccine efficacy against symptomatic NAAT positive infection was similar for B.1.1.7 and non-B1.1.7 lineages (74.6% [95%CI 41.6-88.9] and 84% [95% CI 70.7-91.4] respectively). There was no difference in anti-spike antibody titres between individuals who had received a prior ChAdOx1 vectored vaccine and those who were naïve to ChAdOx1.Interpretation: Efficacy of ChAdOx1 nCoV-19 against the B.1.1.7 variant of SARS-CoV-2 is similar to the efficacy of the vaccine against other lineages. Furthermore, vaccination with ChAdOx1 nCoV-19 results in a reduction in the duration of shedding and viral load, which may translate into a material impact on transmission of disease.
    1. Background: The ChAdOx1 nCoV-19 (AZD1222) vaccine has been approved for emergency use by the UK regulatory authority, MHRA, with a regimen of two standard doses given with an interval of between 4 and 12 weeks. The planned rollout in the UK will involve vaccinating people in high risk categories with their first dose immediately, and delivering the second dose 12 weeks later.Here we provide both a further prespecified pooled analysis of trials of ChAdOx1 nCoV-19 and exploratory analyses of the impact on immunogenicity and efficacy of extending the interval between priming and booster doses. In addition, we show the immunogenicity and protection afforded by the first dose, before a booster dose has been offered.Methods: We present data from phase III efficacy trials of ChAdOx1 nCoV-19 in the United Kingdom and Brazil, and phase I/II clinical trials in the UK and South Africa, against symptomatic disease caused by SARS-CoV-2. The data cut-off date for these analyses was 7th December 2020. The accumulated cases of COVID-19 disease at this cut-off date exceeds the number required for a pre-specified final analysis, which is also presented. As previously described, individuals over 18 years of age were randomised 1:1 to receive two standard doses (SD) of ChAdOx1 nCoV-19 (5x1010 viral particles) or a control vaccine/saline placebo. In the UK trial efficacy cohort a subset of participants received a lower dose (LD, 2.2x1010 viral particles) of the ChAdOx1 nCoV-19 for the first dose. All cases with a nucleic acid amplification test (NAAT) were adjudicated for inclusion in the analysis, by a blinded independent endpoint review committee. Studies are registered at ISRCTN89951424 and ClinicalTrials.gov; NCT04324606, NCT04400838, and NCT04444674.Findings: 17,177 baseline seronegative trial participants were eligible for inclusion in the efficacy analysis, 8948 in the UK, 6753 in Brazil and 1476 in South Africa, with 619 documented NAAT +ve infections of which 332 met the primary endpoint of symptomatic infection >14 days post dose 2.The primary analysis of overall vaccine efficacy >14 days after the second dose including LD/SD and SD/SD groups, based on the prespecified criteria was 66.7% (57.4%,  74.0%). There were no hospitalisations in the ChAdOx1 nCoV-19 group after the initial 21 day exclusion period, and 15 in the control group.Vaccine efficacy after a single standard dose of vaccine from day 22 to day 90 post vaccination was 76% (59%, 86%), and modelled analysis indicated that protection did not wane during this initial 3 month period. Similarly, antibody levels were maintained during this period with minimal waning by day 90 day (GMR 0.66, 95% CI 0.59, 0.74).In the SD/SD group, after the second dose, efficacy was higher with a longer prime-boost interval: VE 82.4% 95%CI 62.7%, 91.7% at 12+ weeks, compared with VE 54.9%, 95%CI 32.7%, 69.7% at <6 weeks. These observations are supported by immunogenicity data which showed binding antibody responses more than 2-fold higher after an interval of 12 or more weeks compared with and interval of less than 6 weeks GMR 2.19 (2.12, 2.26) in those who were 18-55 years of age.Interpretation: ChAdOx1 nCoV-19 vaccination programmes aimed at vaccinating a large proportion of the population with a single dose, with a second dose given after a 3 month period is an effective strategy for reducing disease, and may be the optimal for rollout of a pandemic vaccine when supplies are limited in the short term.Trial Registration: Studies are registered at ISRCTN89951424 and ClinicalTrials.gov; NCT04324606, NCT04400838, and NCT04444674.Funding: UKRI, NIHR, CEPI, the Bill & Melinda Gates Foundation, the Lemann Foundation, Rede D’OR, the Brava and Telles Foundation, NIHR Oxford Biomedical Research Centre, Thames Valley and South Midland's NIHR Clinical Research Network, and Astra Zeneca.Conflict of Interest: Oxford University has entered into a partnership with Astra Zeneca for further development of ChAdOx1 nCoV-19. SCG is co-founder of Vaccitech (collaborators in the early development of this vaccine candidate) and named as an inventor on a patent covering use of ChAdOx1-vectored vaccines and a patent application covering this SARS-CoV-2 vaccine. TL is named as aninventor on a patent application covering this SARS-CoV-2 vaccine and was a consultant to Vaccitech for an unrelated project. PMF is a consultant to Vaccitech. AJP is Chair of UK Dept.Health and Social Care’s (DHSC) Joint Committee on Vaccination & Immunisation (JCVI), but does not participate in discussions on COVID-19 vaccines, and is a member of the WHO’sSAGE. AJP and SNF are NIHR Senior Investigator. The views expressed in this article do not necessarily represent the views of DHSC, JCVI, NIHR or WHO. AVSH reports personal feesfrom Vaccitech, outside the submitted work and has a patent on ChAdOx1 licensed to Vaccitech, and may benefit from royalty income to the University of Oxford from sales of this vaccine by AstraZeneca and sublicensees. MS reports grants from NIHR, non-financial support fromAstraZeneca, during the conduct of the study; grants from Janssen, grants fromGlaxoSmithKline, grants from Medimmune, grants from Novavax, grants and non-financialsupport from Pfizer, grants from MCM, outside the submitted work. CG reports personal fees from the Duke Human Vaccine Institute, outside of the submitted work. SNF reports grants from Janssen and Valneva, outside the submitted work. ADD reports grants and personal fees from AstraZeneca, outside of the submitted work. In addition, ADD has a patent manufacturingprocess for ChAdOx vectors with royalties paid to AstraZeneca, and a patent ChAdOx2 vector with royalties paid to AstraZeneca. The other authors declare no competing interests.
    1. If you’re feeling that herd immunity is the zombie idea of the pandemic that refuses to die, you’re about to see it resurrected in earnest. This time, however, the talk ought to be about the context in which herd immunity was only ever meant to be applied: a vaccination programme.
    1. The purpose of this brief paper is to suggest key principles for co-production of guidance relating to the control of COVID-19, especially where that guidance is expected to be implemented locally by institutions, communities and small businesses. We understand co-production to be the processes and activities by which specific outputs, whether policy, guidance or tools, are created between those traditionally viewed as the ‘decision-makers’ and those groups traditionally viewed as ‘subjected’ to those outputs(Davies, Wetherell & Barnett, 2006; Wright, Corner, Hopkinson & Foster, 2006). It is a practice that amplifies local expertise and practical, embedded knowledge of the problems, and implications of any proposed policy(Hurtig, 2008). Whilst co-production inevitablyrequires some time and resourcesduring the design of an intervention, even a minor investment in working with the implementersand targets ofinterventions will be repaid in terms of enhanced effectiveness.Co-production can be as short as a few hours of consultation with key stakeholders and as long as weeks or months. However, in this rapidly changing environment, a little bit of well-planned, well-prepared co-production can go a long way towards preventing implementation failures, either due to irrelevance or unacceptability, later on.We suggest three key principles for what optimal co-production would look like, highlightfour criteria to understand whether co-production has been effective, and providepractical steps for undertaking co-production before presenting two cases where co-production was undertaken quickly to inform pressing policy needs.
    1. The second year since the genome sequencing of the new coronavirus has begun. And it’s off to a drama-packed start. Major outbreaks in several countries were breeding grounds for mutant strains that are crushing their communities and spreading across the globe. There’s been fierce debates about efficacy of some vaccines – and there are lots of confusing claims and data.
    1. The U.S.′ first case of Covid-19 was reported by the CDC on Jan. 21, 2020.Since then, the country has recorded more than 24 million cases and 400,000 deaths.Experts in public health, science, industry and government reflect on what we’ve learned.
    1. Frankfurt defined persuasive communication that has no regard for truth, knowledge, or evidence as bullshit. Although there has been a lot of psychological research on pseudo-profound bullshit, no study examined this type of communication in politics. In the present research, we operationalize political bullshit receptivity as endorsing vague political statements, slogans, and political bullshit programs. We investigated the relationship of these three measures with pseudo-profound bullshit, ideology (political ideology, support for neoliberalism), populism, and voting behavior. Three pre-registered studies in different cultural settings (the United States, Serbia, The Netherlands; total N = 534) yielded medium to high intercorrelations between political bullshit measures and pseudo-profound bullshit, and good construct validity (hypothesized one-factor solution). A Bayesian meta-analysis showed that all political bullshit measures positively correlated with support for the free market, while only some positively correlated with social (political statements and programs) and economic conservatism (programs), and populism (programs). In the U.S., higher receptivity to political bullshit was associated with a higher probability that one voted for Trump (vs Clinton) in the past and higher intentions to vote for Trump (vs Biden and Sanders). In the Netherlands, higher receptivity to political bullshit predicted the intention to vote for the conservative-liberal People's Party for Freedom and Democracy. Exploratory analyses on merged datasets showed that higher receptivity to political bullshit was associated with a higher probability to vote for right-wing candidates/parties and lower probability for the left-wing ones. Overall, political bullshit endorsement showed good validity, opening avenues for research in political communication, especially when this communication is broad and meaningless.
    1. As more of the population is vaccinated, an increasing number of people have antibodies against SARS-CoV-2, either via infection or, more safely, via inoculation. Many experts have pointed to vaccination as a way to limit future evolution of the coronavirus into new and possibly more dangerous variants. The overall immune status of an entire population can in essence serve as an evolutionary selection pressure; but that assumes there is enough replication going on for mutations to be under positive selection—meaning that mutations don't just occur but that there are conditions that either favor or disfavor that new version of virus by virtue of some change in its structure and therefore its "behavior."
    1. To test whether acute infection with B.1.1.7 is associated with higher or more sustained nasopharyngeal viral concentrations, we assessed longitudinal PCR tests performed in a cohort of 65 individuals infected with SARS-CoV-2 undergoing daily surveillance testing, including seven in fected with B.1.1.7. For individuals infected with B.1.1.7, the mean duration of the proliferation phase was 5.3 days (90% credible interval [2.7, 7.8]), the mean duration of the clearance phase was 8.0 days [6.1, 9.9], and the mean overall duration of infection (proliferation plus clearance) was 13.3 days [10.1, 16.5]. These compare to a mean proliferation phase of 2.0 days [0.7, 3.3], a mean clearance phase of 6.2 days [5.1, 7.1], and a mean duration of infection of 8.2 days [6.5, 9.7] for non-B.1.1.7 virus. The peak viral concentration for B.1.1.7 was 19.0 Ct [15.8, 22.0] compared to 20.2 Ct [19.0, 21.4] for non-B.1.1.7. This converts to 8.5 log10 RNA copies/ml [7.6, 9.4] for B.1.1.7 and 8.2 log10 RNA copies/ml [7.8, 8.5] for non-B.1.1.7. These data offer evidence that SARS-CoV-2 variant B.1.1.7 may cause longer infections with similar peak viral concentration compared to non-B.1.1.7 SARS-CoV-2. This extended duration may contribute to B.1.1.7 SARS CoV-2’s increased transmissibility.
    1. Since the start of the coronavirus COVID-19 pandemic, the term “herd immunity” has been all over the news. But what does it really mean? One thing most people don’t realize about vaccines is that they aren’t just to protect the person who gets the shot. They also protect the population as a whole… even people who didn’t get the shot. In this video, we use lots and lots of mousetraps and ping-pong balls to show you how that works.
    1. It is imperative to dispel any ambiguity about how vaccine efficacy shown in trials translates into protecting individuals and populations.
    1. On 6 January, gastroenterologist Leolin Katsidzira received a troubling message from his colleague James Gita Hakim, a heart specialist and noted HIV/AIDS researcher. Hakim, chair of the department of medicine at the University of Zimbabwe, had fallen sick and had tested positive for COVID-19. He was admitted to a hospital in Harare 10 days later and moved to an intensive care unit (ICU) after his condition deteriorated. He died on 26 January.
    1. An extra 1.7 million people in England will be added to the list of those identified as clinically extremely vulnerable to covid-19, as a result of new modelling first published in The BMJ.1
    1. Treasurer says Facebook has 'damaged its reputation' with Australian news ban Company says it has made decision ‘with a heavy heart’ in response to proposed media bargaining code
    1. Vulnerable children must be at the heart of government plans to "build back better" after the pandemic, England's children's commissioner says.
    1. In this paper, we investigate the human ability to distinguish political social bots from humans on Twitter. Following motivated reasoning theory from social and cognitive psychology, our central hypothesis is that especially those accounts which are opinion-incongruent are perceived as social bot accounts when the account is ambiguous about its nature. We also hypothesize that credibility ratings mediate this relationship. We asked N = 151 participants to evaluate 24 Twitter accounts and decide whether the accounts were humans or social bots. Findings support our motivated reasoning hypothesis for a sub-group of Twitter users (those who are more familiar with Twitter): Accounts that are opinion-incongruent are evaluated as relatively more bot-like than accounts that are opinion-congruent. Moreover, it does not matter whether the account is clearly social bot or human or ambiguous about its nature. This was mediated by perceived credibility in the sense that congruent profiles were evaluated to be more credible resulting in lower perceptions as bots.
    1. Online hate speech is a growing concern, with minorities and vulnerable groups increasingly targeted with extreme denigration and hostility. The drivers of hate speech expression on social media are unclear, however. This study explores how hate speech develops on a fringe social media platform popular with the far-right, Gab. We investigate whether users seek out this platform in order to express hate, or whether instead they develop these opinions over time through a mechanism of socialisation, as they interact with other users on the platform. We find a positive association between the time users spend on the platform and their hate speech expression. We show that while some users do arrive on these platforms with pre-existing hate stances, others develop these expressions as they get exposed to the hateful opinions of others. Our analysis reveals how hate speech develops online, the important role of the group environment in accelerating its development, and gives valuable insight to inform the development of counter measures.
    1. Conspiracism is not restricted to the fringe dwellers of society. International research suggests that such beliefs are quite common and that conspiracy theories may serve three basic psychological motives (i.e., epistemic, existential, and relational) for individuals. Yet, little is known about conspiracy theory awareness or conspiracism in Australasia. We report the first large systematic investigation of system justifying motives using two nationally representative samples of Australians (n = 1,011) and New Zealanders (n = 754). Our findings show that almost all are aware of local and international conspiracies, and the majority endorse one or more. Also, that all three psychological motives consistently relate to conspiracism but not to awareness. In a series of hierarchical multiple regressions, we find that epistemic (i.e., decreased analytic thinking), existential (i.e., less trust in others, and socially conservative political ideology and increased religiosity), and relational motives (i.e., increased anomie and disillusionment with the government) were all significant unique predictors of increased local and international conspiracism. Findings are discussed in terms of the importance of understanding conspiracism as an ideological belief system that may function to serve underlying psychological motives.
    1. Background: COVID-19 is a major health problem because of acute respiratory distress syndrome, saturation of intensive care units (ICU) and mortality. Methods: Our study aims to elucidate the effect of calcifediol [25(OH)D3] treatment on ICU admission and mortality, in patients admitted to COVID-19 wards of Hospital del Mar, Barcelona, Spain. A total of 930 participants were included. Participants (n=551) were randomly assigned to calcifediol treatment (532 ug on day one and 266 ug on day 3, 7, 15, and 30) at the time of hospital admission or as controls (n=379).Findings: ICU assistance was required by 110 (11.8%) participants. Out of 551 patients treated with calcifediol at admission, 30 (5.4%) required ICU, compared to 80 out of 379 controls (21.1%; p<0.0001). Logistic regression of calcifediol treatment on ICU admission, adjusted by age, gender, linearized 25(OH)D levels at baseline, and comorbidities showed that treated patients had a reduced risk to require ICU (RR 0.18 [95% CI 0.11;0.29]). Baseline 25(OH)D levels inversely correlated with the risk of ICU admission (RR 0.53 [95% CI 0.35;0.80]). Overall mortality was 10%. In the Intention-to-treat analysis, 36 (6.5%) out of 551 patients treated with calcifediol at admission died compared to 57 patients (15%) out of 379 controls (p=0.001). Adjusted results showed a reduced mortality for more of 60%. Higher baseline 25(OH)D levels were significantly associated with decreased mortality (RR 0.40 [95% CI 0.24;0.67]). Age and obesity were also predictors of mortality. Interpretation: In patients hospitalized with COVID-19, calcifediol treatment at the time of hospitalization significantly reduced ICU admission and mortality.
    1. The UK and California variants of coronavirus appear to have combined into a heavily mutated hybrid, sparking concern that we may be entering a new phase of the covid-19 pandemic
    1. For the first time, all the UK's mobile networks are sending out a government message to their customers with details of the new shutdown measures.
    1. The badly thought-out use of Microsoft's Excel software was the reason nearly 16,000 coronavirus cases went unreported in England.
    1. LONDON (Reuters) - AstraZeneca expects to have results from a U.S. clinical trial of its COVID-19 vaccine in the next four to six weeks, the company’s research chief Mene Pangalos said on Friday.
    1. The world is facing a race between controlling new and more infectious variants of coronavirus and implementing vaccinations: How can health authorities and governments most effectively communicate the need to engage more strongly in protective behavior to avoid a collapse of the healthcare system until vaccination programs are effective? In the first wave of the pandemic, citizens became engaged in `flattening the curve' via powerful visualizations. Here, we use epidemiological modelling to develop a new visual communication aid, `buying time with hope', which reflects the pandemic trade-offs currently facing governments, authorities and citizens. Using a population-based experiment conducted in United States (N = 3,022), we demonstrate that this hope-oriented visual communication aid, depicting the competing effects on the epidemic curve of (1) more infectious variants and (2) vaccinations, motivates public action and communicates more effectively than fear-oriented visual communication, focusing exclusively on the threat of the new variants. Finally, using cross-national representative surveys from eight countries (N = 3,995), we document the urgent need to motivate public action to halt the spread of the new, more infectious variants. These findings not only provide public health authorities globally with a validated blueprint for health communication in a critical period of the pandemic but also provide general psychological insights into the importance of hope as a health communication strategy.
    1. We show that governor charisma can affect individual behavior to help mitigate COVID-related outcomes. We provide evidence in the field using deep neural ratings of charisma of governor speeches over time to explain physical distancing based on anonymized data from smart phones. We also show in an incentivized laboratory experiment that individuals who are conservative are more responsive to charismatic appeals of a governor, which drives their beliefs on whether their co-citizens will physically distance; these beliefs in turn appear to affect their behavior too. Interestingly, liberals are unaffected by charisma, as a result of their preference to physically distance regardless. These findings are important because they show that a learnable skill—or at least one that can be honed—can give leaders an additional weapon to complement policy interventions for pandemics, especially with certain populations who may need a “nudge,” and hence save lives.
    1. The COVID-19 pandemic massively changed the context and feasibility of developmental research. This new reality as well as considerations, e.g., about sample diversity and naturalistic settings for developmental research, indicate the need for solutions for online studies. In this article, we present e-Babylab, an open-source browser-based tool for unmoderated online studies specifically targeted at studying young children and babies. e-Babylab offers an intuitive graphical user interface for study creation and management of studies, users, participant data, and stimulus material with no programming skills required. Various kinds of audiovisual media can be presented as stimuli and possible measures include webcam recordings, audio recordings, key presses, mouse-click/touch coordinates, and reaction times. Information pages, consent forms, and participant forms are all customizable. e-Babylab was used with a variety of measures and paradigms in 14 studies with children aged 12 months to 8 years (n = 1516). We briefly summarize some results of these studies to demonstrate data quality and that participants’ engagement and the overall results are comparable in lab and online settings. We then present in more detail one replication of an established preferential-looking paradigm with gaze directions manually coded from the webcam captures. Finally, we discuss useful tips for using e-Babylab and present plans for upgrades.
    1. Curiosity is a powerful determinant of behavior. The past decade has seen a surge of scientific research on curiosity, an endeavor recently imbibed with urgency by the WHO, which set managing information-seeking as a public health goal during pandemics. And yet, a fundamental aspect of curiosity has remained unresolved: its relationship to utility. Is curiosity a drive towards information simply for the sake of obtaining that information, or is it a rational drive towards optimal learning? We leveraged people’s curiosity about COVID-19 to study information-seeking and learning in a large sample (n=5376) during the spring of 2020. Our findings reveal that curiosity is goal-rational in that it maximizes the personal utility of learning. Personal utility, unlike normative economic utility, is contingent on a person’s motivational state. On the basis of these findings, we explain information-seeking during the pandemic with a rational theoretical framework for curiosity.
    1. The potential impact of COVID-19 restrictions on worker well-being is currently unknown. In this study we examine 15 well-being outcomes collected from 621 full-time workers assessed before (November, 2019 - February, 2020) and during (May-June, 2020) the COVID-19 pandemic. Fixed effects analyses are used to investigate how the COVID-19 restrictions and involuntary homeworking affect well-being and job performance. The majority of worker well-being measures are not adversely affected. Homeworkers feel more engaged and autonomous, experience fewer negative emotions and feel more connected to their organisations. However, these improvements come at the expense of reduced homelife satisfaction and job performance.
    1. The COVID-19 pandemic has caused controversy over new norms of mask-wearing in public places. An online experiment previously showed that people from several Spanish-speaking countries perceived faces wearing medical-style masks as more trustworthy, socially desirable, and likely to be ill, compared to control faces without a mask. We replicated and extended these methods with 1241 English-speaking participants from the UK and USA, adding questions on political orientation and voting intention, and including the online-VAAST task to test the effects of masks on an implicit reaction-time measure. The positive effects of masks on trustworthiness and social desirability were replicated, but the negative effect of masks on perceptions of healthiness was reversed. Participants were also quicker to approach masked faces. Conservative voters’ explicit and implicit reactions to masked faces were less favorable than those of liberals, demonstrating that masks are viewed positively by many but continue to be politically controversial.
    1. One of the challenges during the post-COVID pandemic era will be to foster social connections between people. Previous research suggests that people who is able to regulate their emotions tends to have better social connections with others. Additional studies indicate that it is possible to train the ability to regulate emotions voluntarily, using a procedure that involves three steps: (1) asking participants to evoke an autobiographical memory associated with a positive emotion; (2) analyze participants’ brain activity in real-time to estimate their emotional state; and (3) provide visual feedback about the emotions evoked with the autobiographical memory. However, there is not enough research on how to provide the visual feedback required for the third step. Therefore, this manuscript introduces five virtual environments that can be used to provide emotional visual feedback. Each virtual environment was designed based on evidence found in previous studies, suggesting that there are visual cues, such as colors, shapes and motion patterns, that tend to be associated with emotions. In each virtual environment, the visual cues changed, intending to represent five emotional categories. An experiment was conducted to analyze the emotions that participants associated with the virtual environments. The results indicate that each environment is associated with the emotional categories that they were meant to represent.
    1. The mitigation efforts of COVID-19 have led to significant changes to the delivery of routine healthcare globally. In Australia, the way maternal health services have been delivered since the beginning of the pandemic has also changed. Maternity care and support are known to influence maternal mental health. One hundred and eighty-eight English speaking pregnant women residing in Australia were recruited using social media advertising between September and November 2020 as part of a larger study. Participants were aged between 19 and 42 (M = 31.05, SD = 4.68). Compared with previous Australian prevalence rates of around 7% for antenatal depression, rates in this study were 15.9% overall and 19% for those in Melbourne. It is suggested that increased vigilance with screening and assessment will be required to identify and support this cohort of mothers who are not coping.
    1. Prior research using economic games has shown that personality drives cooperation in social dilemmas. In this study, we tested the generalizability of these findings in a real-life social di-lemma during the COVID-19 pandemic, namely stockpiling in the presence of low versus high resource scarcity. Honesty-Humility was negatively related to stockpiling intentions and justi-fiability of stockpiling. Moreover, we found a positive albeit weaker effect of Emotionality on stockpiling intentions. Victim Sensitivity was mostly positively associated with stockpiling intentions. None of the personality traits interacted with resource scarcity to predict stockpil-ing. Our findings replicate established associations between personality and cooperation in a real-life social dilemma, and suggest that the characteristics of interdependent situations during a pandemic additionally afford the expression of Emotionality.
    1. Face perception is considered a remarkable visual ability in humans, which is subject to a prolonged developmental trajectory. In response to the COVID-19 pandemic, mask-wearing has become mandatory for adults and children alike. However, previous research indicates its adverse effects on face recognition abilities in adults. The current study sought to explore the effect of masks on face processing abilities in school-age children given that face perception is not fully developed in this population. To this end, children (n = 72, ages 6-14 years old) completed the Cambridge Face Memory Test – Kids (CFMT-K), a validated measure of face perception performance. Faces were presented with or without masks and across two orientations (upright/inverted). The inclusion of face masks led to a profound deficit in face perception abilities. This decrement was more pronounced in children compared to adults, despite adjustment of task difficulty across the two age groups. Additionally, children exhibited reliable correlations between age and the CFMT score for upright faces for both the mask and no-mask conditions. Finally, as previously observed in adults, children also showed qualitative changes in the processing of masked faces. Specifically, holistic processing, a hallmark of face perception, was disrupted for masked faces, as suggested by a reduced face-inversion effect. Together, these findings provide evidence for substantial quantitative and qualitative alterations in the processing of masked faces in school-age children.
    1. Objective: There is limited existing research on the structure of routine and mental wellbeing. During March 2020, the UK entered a national lockdown, causing a sudden change in undergraduate students’ routines. This study uses this event to investigate the impact routine change had on students’ mental wellbeing; in particular looking at depression, anxiety, sleep disturbance, and eating behaviours. Method: Participants reported their daily routine timings (waking, breakfast, lunch, evening meal and bedtime) and activities (e.g. exercise amount, time with friends, time studying, etc) on a typical Monday, Wednesday and Saturday during term time and lockdown. Additionally they completed the PROMIS measures of anxiety, depression, and sleep disturbance, and the Eating Pathology Symptom Inventory. Results: Lockdown saw small but significant shifts in routine timing (on average 1.5 hours) However, there was no clear overall pattern of relationships between mental wellbeing and routine structure or magnitude of routine change. There was some evidence of changes in amount of exercise relating to reported anxiety. Discussion: These findings are consistent with the current literature reporting lockdown effects on behaviour. Routine timings shifted but this change was small and there was minimal impact of routine change on mental wellbeing reported by undergraduate students. The change in amount of exercise posed by lockdown did appear to be an important factor in wellbeing, and more research should focus on the wellbeing implications of closing places for exercise.