6 Matching Annotations
  1. Mar 2021
    1. We have a problem here with analogies: the so-called “vaccine resistance” is not like antibiotic resistance. Our mental models of “resistance” come mostly from antibiotics, but this analogy isn’t applicable here in the same way. Vaccines aren’t drugs; they are tools to give our immune system test practice so that when the real thing shows up, our body knows what to do. When antibiotics don’t work, they don’t work. Not so here. If the test practice isn’t as precise because the variant is a little different around the spike protein, the conclusion isn’t necessarily that the immune system won’t be able to do its job and stave off illness.

      Antibiotic resistance is not the same thing as vaccine "resistance".

  2. Jun 2019
    1. response to antimicrobial agents can greatly vary, depending on the location of a particular cell within a biofilm community
  3. Sep 2018
    1. Furthermore, drugs targeting the gut-liver axis (e.g. intregrin blockers such as vedolizumab, antibiotics) appear promising, based on the close link of PSC to inflammatory bowel disease and the emerging relevance of the gut microbiome for the development of PSC.

      This doesn't mention Vancomycin. Is Vanco an integrin blocker?

  4. Sep 2017
    1. In space, bacteria “shapeshifts” to defend itself against antibiotics, experiments on board the International Space Station (ISS) have revealed. The discovery potentially poses a big problem for future space travel—as long duration missions happen more frequently, we will need antibiotics to treat sick astronauts. But if space bacteria is able to quickly and effectively develop resistance, common infections could become deadly.

      This is alarming!

  5. Apr 2017
    1. a dark horse that may help to save the day against these seemingly invincible “superbugs”: the Komodo dragon. This rare animal’s blood contains antibiotics that may be useful in stopping diseases in humans.

      Wow, who would think to check this?

  6. Oct 2016
    1. Shu Lam, a 25-year-old PhD student at the University of Melbourne in Australia, has developed a star-shaped polymer that can kill six different superbug strains without antibiotics, simply by ripping apart their cell walls.

      ...

      Before we get too carried away, it's still very early days. So far, Lam has only tested her star-shaped polymers on six strains of drug-resistant bacteria in the lab, and on one superbug in live mice.

      http://www.nature.com/articles/nmicrobiol2016162