343 Matching Annotations
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    Transcriptional regulators ensuring specific gene expression and decision making at high TGFβ doses
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    1. EMBOpress 03 Dec 2024

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    biorxiv.org/content/10.1101/2024.04.23.590740v1
  3. Nov 2024
  4. www.biorxiv.org www.biorxiv.org
    Mass spectrometry-based proteomic exploration of diverse murine macrophage cellular models
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    1. EMBOpress 27 Nov 2024

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    biorxiv.org/content/10.1101/2024.04.09.588684v1
  5. www.biorxiv.org www.biorxiv.org
    Structural and biochemical analysis of ligand binding in yeast Niemann-Pick type C1-related protein
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    1. EMBOpress 27 Nov 2024

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    biorxiv.org/content/10.1101/2024.06.10.598172v2
  6. www.biorxiv.org www.biorxiv.org
    Cell–cell adhesion drives patterning in stratified epithelia
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    1. EMBOpress 14 Nov 2024

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    biorxiv.org/content/10.1101/2023.11.24.567740v1
  7. www.biorxiv.org www.biorxiv.org
    Deregulation of multiple mechanisms shapes the onset of LAMA2-congenital muscular dystrophy
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    1. EMBOpress 08 Nov 2024

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    biorxiv.org/content/10.1101/2024.01.20.576409v1
  8. www.biorxiv.org www.biorxiv.org
    CENP-C-Mis12 complex establishes a regulatory loop through Aurora B for chromosome segregation
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    1. EMBOpress 02 Nov 2024

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    biorxiv.org/content/10.1101/2024.05.29.596395v1
  9. www.biorxiv.org www.biorxiv.org
    The hGID GID4 E3 ubiquitin ligase complex targets ARHGAP11A to regulate cell migration
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    1. EMBOpress 01 Nov 2024

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    biorxiv.org/content/10.1101/2023.07.20.549906v1
  10. www.biorxiv.org www.biorxiv.org
    Naa80 is required for actin N-terminal acetylation and normal hearing in zebrafish
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    1. EMBOpress 01 Nov 2024

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    biorxiv.org/content/10.1101/2024.03.17.585386v1
  11. Oct 2024
  12. www.biorxiv.org www.biorxiv.org
    TMX5/TXNDC15, a natural trapping mutant of the PDI family is a client of the proteostatic factor ERp44
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    1. EMBOpress 11 Oct 2024

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    biorxiv.org/content/10.1101/2024.06.12.598629v1
  13. www.biorxiv.org www.biorxiv.org
    Metabolic resistance of Abeta3pE-42, epitope of the anti-Alzheimer therapeutic antibody, donanemab.
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    1. EMBOpress 11 Oct 2024

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    biorxiv.org/content/10.1101/2024.01.30.578111v1
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    Dysfunctional β-cell longevity in diabetes relies on energy conservation and positive epistasis
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    1. EMBOpress 08 Oct 2024

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    biorxiv.org/content/10.1101/2024.03.18.585508v1
  15. www.biorxiv.org www.biorxiv.org
    Non-redundant roles for the human mRNA decapping cofactor paralogs DCP1a and DCP1b
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    1. EMBOpress 04 Oct 2024

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    biorxiv.org/content/10.1101/2023.10.19.563039v1
  16. www.biorxiv.org www.biorxiv.org
    FAM111A regulates replication origin activation and cell fitness
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    1. EMBOpress 04 Oct 2024

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    biorxiv.org/content/10.1101/2020.04.22.055574v1
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    Regulation of proteostasis by sleep through autophagy in Drosophila models of Alzheimer's Disease
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    1. EMBOpress 04 Oct 2024

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    biorxiv.org/content/10.1101/2024.07.01.601554v1
  18. www.biorxiv.org www.biorxiv.org
    Differential Modulation of Polycomb-Associated Histone Marks by cBAF, pBAF, and gBAF Complexes
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    1. EMBOpress 03 Oct 2024

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    biorxiv.org/content/10.1101/2023.09.23.557848v2
  19. www.biorxiv.org www.biorxiv.org
    A Novel Role for CSA in the Regulation of Nuclear Envelope Integrity: Uncovering a Non-Canonical Function
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    1. EMBOpress 03 Oct 2024

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    biorxiv.org/content/10.1101/2023.12.14.571633v1
  20. www.biorxiv.org www.biorxiv.org
    Reprogramming of breast tumor-associated macrophages with modulation of arginine metabolism
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    1. EMBOpress 03 Oct 2024

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    biorxiv.org/content/10.1101/2023.08.22.554238v1
  21. Sep 2024
  22. www.biorxiv.org www.biorxiv.org
    Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction in C9orf72 ALS/FTD in vivo models and patient iNeurons
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    1. EMBOpress 24 Sep 2024

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    biorxiv.org/lookup/doi/10.1101/2023.10.02.560439
  23. www.biorxiv.org www.biorxiv.org
    Proteomic analysis reveals microvesicles containing NAMPT as mediators of radiation resistance in glioma
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    1. EMBOpress 11 Sep 2024

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    biorxiv.org/lookup/doi/10.1101/2022.03.23.485479
  24. www.biorxiv.org www.biorxiv.org
    De-tensioning of collagen fibers optimizes endometrial receptivity and improves the rate of embryo implantation
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    1. EMBOpress 10 Sep 2024

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    biorxiv.org/lookup/doi/10.1101/2022.01.18.476712
  25. www.biorxiv.org www.biorxiv.org
    A highly scalable approach to topic modelling in single-cell data by approximate pseudobulk projection
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    1. EMBOpress 10 Sep 2024

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    biorxiv.org/lookup/doi/10.1101/2024.02.21.581497
  26. Aug 2024
  27. www.biorxiv.org www.biorxiv.org
    Passive diffusion accounts for the majority of intracellular vesicle transport
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    1. EMBOpress 20 Aug 2024

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    biorxiv.org/content/10.1101/2023.05.10.540182v1
  28. www.biorxiv.org www.biorxiv.org
    RedRibbon: A new rank-rank hypergeometric overlap pipeline to compare gene and transcript expression signatures
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    1. EMBOpress 01 Aug 2024

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    biorxiv.org/content/10.1101/2022.08.31.505818v1
  29. Jul 2024
  30. www.biorxiv.org www.biorxiv.org
    Global Huntingtin Knockout in Adult Mice Leads to Fatal Neurodegeneration that Spares the Pancreas
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    1. EMBOpress 31 Jul 2024

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    biorxiv.org/content/10.1101/2024.01.11.575238v1
  31. www.biorxiv.org www.biorxiv.org
    Defective Integrator activity shapes the transcriptome of patients with multiple sclerosis
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    1. EMBOpress 30 Jul 2024

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    biorxiv.org/content/10.1101/2023.11.24.568591v2
  32. www.biorxiv.org www.biorxiv.org
    A large-scale cancer-specific protein-DNA interaction network
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    1. EMBOpress 30 Jul 2024

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    biorxiv.org/content/10.1101/2024.01.24.577099v1
  33. www.biorxiv.org www.biorxiv.org
    Structure of the human systemic RNAi defective transmembrane protein 1 (hSIDT1) reveals the conformational flexibility of its lipid binding domain
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    1. EMBOpress 24 Jul 2024

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    biorxiv.org/content/10.1101/2023.12.21.572875v2
  34. www.biorxiv.org www.biorxiv.org
    Exploring the molecular composition of the multipass translocon in its native membrane environment
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    1. EMBOpress 02 Jul 2024

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    biorxiv.org/content/10.1101/2023.11.28.569136v1
  35. www.biorxiv.org www.biorxiv.org
    Congress of multiple dimers is needed for cross-phosphorylation of IRE1α and its RNase activity
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    1. EMBOpress 02 Jul 2024

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    biorxiv.org/content/10.1101/2023.12.18.572154v1
  36. Jun 2024
  37. www.biorxiv.org www.biorxiv.org
    Translation inhibition efficacy does not determine the Plasmodium berghei liver stage antiplasmodial efficacy of protein synthesis inhibitors
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    1. EMBOpress 27 Jun 2024

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    biorxiv.org/content/10.1101/2023.12.07.570699v1
  38. www.biorxiv.org www.biorxiv.org
    The type of DNA damage response after Decitabine treatment depends on the level of DNMT activity
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    1. EMBOpress 26 Jun 2024

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    biorxiv.org/content/10.1101/2023.09.02.556017v2
  39. www.biorxiv.org www.biorxiv.org
    Structural analysis of SALL4 zinc-finger domain reveals a link between AT-rich DNA binding and Okihiro syndrome
    1
    1. EMBOpress 05 Jun 2024

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    biorxiv.org/content/10.1101/2022.06.14.495968v1
  40. www.biorxiv.org www.biorxiv.org
    Trim66 paternal deficiency causes intrauterine overgrowth
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    1. EMBOpress 04 Jun 2024

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    biorxiv.org/content/10.1101/2024.02.12.579976v1
  41. www.biorxiv.org www.biorxiv.org
    The concerted action of SEPT9 and EPLIN modulates the adhesion and migration of human fibroblasts
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    1. EMBOpress 04 Jun 2024

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    biorxiv.org/content/10.1101/2022.08.08.503265v1
  42. May 2024
  43. www.biorxiv.org www.biorxiv.org
    DNA binding site II is required for RAD51 recombinogenic activity in Arabidopsis thaliana
    1
    1. EMBOpress 31 May 2024

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    biorxiv.org/content/10.1101/2024.03.07.583932v1
  44. www.biorxiv.org www.biorxiv.org
    Identification of new drugs to counteract anti-spike IgG-induced hyperinflammation in severe COVID-19
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    1. EMBOpress 31 May 2024

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    biorxiv.org/content/10.1101/2022.12.20.521247v1
  45. www.biorxiv.org www.biorxiv.org
    ERLIN1/2 scaffolds bridge TMUB1 and RNF170 and restrict cholesterol esterification to regulate the secretory pathway
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    1. EMBOpress 30 May 2024

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    biorxiv.org/content/10.1101/2024.01.17.576039v1
  46. www.biorxiv.org www.biorxiv.org
    K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific interactors.
    1
    1. EMBOpress 29 May 2024

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    biorxiv.org/content/10.1101/2024.01.08.574586v1
  47. www.biorxiv.org www.biorxiv.org
    IGHMBP2 deletion suppresses translation and activates the integrated stress response
    1
    1. EMBOpress 29 May 2024

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    biorxiv.org/content/10.1101/2023.12.11.571166v2
  48. www.biorxiv.org www.biorxiv.org
    Frataxin Deficiency Drives a Shift from Mitochondrial Metabolism to Glucose Catabolism, Triggering an Inflammatory Phenotype in Microglia
    1
    1. EMBOpress 08 May 2024

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    biorxiv.org/content/10.1101/2023.10.18.562916v1
  49. Apr 2024
  50. www.biorxiv.org www.biorxiv.org
    Integrative DNA methylation analysis of pediatric brain tumors reveals tumor type-specific developmental trajectories and epigenetic signatures of malignancy
    1
    1. EMBOpress 27 Apr 2024

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    biorxiv.org/content/10.1101/2022.03.14.483566v2
  51. www.biorxiv.org www.biorxiv.org
    pADP-ribosylation Regulates the Cytoplasmic Localization, Cleavage and Pro-apoptotic Function of HuR
    1
    1. EMBOpress 25 Apr 2024

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    biorxiv.org/content/10.1101/2023.08.07.552262v1
  52. Mar 2024
  53. www.biorxiv.org www.biorxiv.org
    Circadian Transcriptomic and Epigenomic Remodeling in Response to Lipid Overload and Human Obesity
    1
    1. EMBOpress 09 Mar 2024

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    biorxiv.org/content/10.1101/2021.02.23.432336v4
  54. www.biorxiv.org www.biorxiv.org
    Variable PD-1 glycosylation modulates the activity of immune checkpoint inhibitors
    1
    1. EMBOpress 05 Mar 2024

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    biorxiv.org/content/10.1101/2023.08.25.554811v1
  55. www.biorxiv.org www.biorxiv.org
    Structural and biochemical insights into heterotetramer formation between human oncogenic K-Ras4BG12V and Rgl2, a RalA/B activator
    1
    1. EMBOpress 05 Mar 2024

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    biorxiv.org/content/10.1101/2022.10.10.511529v8
  56. www.biorxiv.org www.biorxiv.org
    The memory of airway epithelium damage in smokers and COPD patients
    1
    1. EMBOpress 05 Mar 2024

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    biorxiv.org/content/10.1101/2021.04.21.439437v3
  57. www.biorxiv.org www.biorxiv.org
    Centriole and transition zone structures in photoreceptor cilia revealed by cryo-electron tomography
    1
    1. EMBOpress 05 Mar 2024

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    biorxiv.org/content/10.1101/2023.10.05.560879v1
  58. www.biorxiv.org www.biorxiv.org
    Micronucleus Is Not a Potent Inducer of cGAS-STING Pathway
    1
    1. EMBOpress 05 Mar 2024

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    biorxiv.org/content/10.1101/2023.10.16.561322v1
  59. www.biorxiv.org www.biorxiv.org
    CLN3 deficiency leads to neurological and metabolic perturbations during early development
    1
    1. EMBOpress 05 Mar 2024

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    biorxiv.org/content/10.1101/2023.03.17.533107v1
  60. www.biorxiv.org www.biorxiv.org
    A nuclear signal in prophase determines centrosome positioning and ensures efficient mitotic spindle assembly
    1
    1. EMBOpress 01 Mar 2024

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    biorxiv.org/content/10.1101/2023.06.14.544905v2
  61. www.biorxiv.org www.biorxiv.org
    The origin, evolution and molecular diversity of the chemokine system
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    1. EMBOpress 01 Mar 2024

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    biorxiv.org/content/10.1101/2023.05.17.541135v2
  62. Feb 2024
  63. www.biorxiv.org www.biorxiv.org
    Histology-associated transcriptomic heterogeneity in ovarian folliculogenesis revealed by quantitative single-cell RNA-sequencing for tissue sections with DRaqL
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    1. EMBOpress 21 Feb 2024

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    biorxiv.org/content/10.1101/2022.12.14.520513v1
  64. www.biorxiv.org www.biorxiv.org
    CRISPR-Cas9-mediated genome engineering exaggerates genomic deletion at 10q23.31 including the PTEN gene locus mimicking cancer profiles
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    1. EMBOpress 03 Feb 2024

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    biorxiv.org/content/10.1101/2023.04.05.535680v1
  65. Jan 2024
  66. www.biorxiv.org www.biorxiv.org
    Proteomic-based stratification of intermediate-risk prostate cancer patients
    1
    1. EMBOpress 26 Jan 2024

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    biorxiv.org/content/10.1101/2023.03.03.530910v1
  67. www.biorxiv.org www.biorxiv.org
    Human RAD52 stimulates the RAD51-mediated homology search
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    1. EMBOpress 25 Jan 2024

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    biorxiv.org/content/10.1101/2022.06.27.497340v1
  68. www.biorxiv.org www.biorxiv.org
    The structural basis for deubiquitination by the fingerless USP-type effector TssM
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    1. EMBOpress 25 Jan 2024

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    biorxiv.org/content/10.1101/2023.08.01.551441v1
  69. www.biorxiv.org www.biorxiv.org
    Changes in searching behaviour of CSL transcription complexes in Notch active conditions
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    1. EMBOpress 23 Jan 2024

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    biorxiv.org/content/10.1101/2023.08.10.552734v2
  70. Dec 2023
  71. www.biorxiv.org www.biorxiv.org
    RIF1 ensures the organization of replication factories upon DNA replicative stress.
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    1. EMBOpress 16 Dec 2023

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    biorxiv.org/content/10.1101/669234v3
  72. www.biorxiv.org www.biorxiv.org
    Decline of DNA damage response along with myogenic differentiation
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    biorxiv.org/content/10.1101/2023.06.27.546688v1
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    Enhancer-driven local 3D chromatin domain folding modulates transcription in human mammary tumor cells
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    1. EMBOpress 15 Dec 2023

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    biorxiv.org/content/10.1101/2023.10.17.562690v1
  74. www.biorxiv.org www.biorxiv.org
    Structural analysis shows that the BIR2 domain of E3 ligase XIAP binds across the RIP2 kinase dimer interface
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    Mitochondrial phosphoproteomes are functionally specialized across tissues
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    biorxiv.org/content/10.1101/2022.03.23.485457v1
  76. www.biorxiv.org www.biorxiv.org
    Enucleation of the C. elegans embryo revealed the mechanism of dynein-dependent spacing between microtubule asters
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    1. EMBOpress 12 Dec 2023

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  77. www.biorxiv.org www.biorxiv.org
    Epithelial lumen development requires differential participation of the vertebrate clathrin light chain isoforms with dominance of CLCa in vivo
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    1. EMBOpress 12 Dec 2023

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    biorxiv.org/content/10.1101/2023.04.25.538235v2
  78. www.biorxiv.org www.biorxiv.org
    Identification of FAM53C as a suppressive binding protein of a neurodevelopmental disorders-related kinase DYRK1A
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    1. EMBOpress 12 Dec 2023

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    biorxiv.org/content/10.1101/2023.04.21.537794v2
  79. www.biorxiv.org www.biorxiv.org
    Modeling of Aberrant Epithelial Reprogramming in Idiopathic Pulmonary Fibrosis using Human Induced Pluripotent Stem Cell-derived Alveolar Organoids
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    biorxiv.org/content/10.1101/2022.06.15.496102v1
  80. www.biorxiv.org www.biorxiv.org
    Automated staging of zebrafish embryos with deep learning
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    1. EMBOpress 09 Dec 2023

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    biorxiv.org/content/10.1101/2023.01.13.523922v2
  81. www.biorxiv.org www.biorxiv.org
    NRF2 connects Src tyrosine kinase to ferroptosis resistance in glioblastoma
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    1. EMBOpress 09 Dec 2023

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    biorxiv.org/content/10.1101/2023.05.08.539792v1
  82. www.biorxiv.org www.biorxiv.org
    MICA: A multi-omics method to predict gene regulatory networks in early human embryos
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    1. EMBOpress 09 Dec 2023

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    biorxiv.org/content/10.1101/2023.02.03.527081v2
  83. Nov 2023
  84. www.biorxiv.org www.biorxiv.org
    Expansion microscopy reveals subdomains in C. elegans germ granules
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    1. EMBOpress 30 Nov 2023

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    biorxiv.org/content/10.1101/2022.05.29.493872v1
  85. www.biorxiv.org www.biorxiv.org
    Revisiting degron motifs in human AURKA required for its targeting by APC/C-FZR1
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    1. EMBOpress 07 Nov 2023

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    biorxiv.org/content/10.1101/2022.01.31.478464v2
  86. Oct 2023
  87. www.biorxiv.org www.biorxiv.org
    High Resolution Kinetic Characterization and Dynamic Mathematical Modeling of the RIG-I Signaling Pathway and the Antiviral Responses
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    1. EMBOpress 07 Oct 2023

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    biorxiv.org/content/10.1101/2022.08.05.502818v1
  88. Sep 2023
  89. www.biorxiv.org www.biorxiv.org
    Caspase-4 dimerisation and D289 auto-processing elicits an interleukin-1β converting enzyme
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    biorxiv.org/content/10.1101/2023.01.05.522955v1
  90. www.biorxiv.org www.biorxiv.org
    Neuroprotective effects of hepatoma-derived growth factor in models of Huntington's disease
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    biorxiv.org/content/10.1101/2023.02.23.529222v1
  91. www.biorxiv.org www.biorxiv.org
    Structural evidence for elastic tethers connecting separating chromosomes in crane-fly spermatocytes
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    biorxiv.org/content/10.1101/2023.05.28.541924v1
  92. www.biorxiv.org www.biorxiv.org
    A novel antifolate suppresses growth of FPGS-deficient cells and overcomes methotrexate resistance
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    biorxiv.org/content/10.1101/2023.02.26.530079v2
  93. www.biorxiv.org www.biorxiv.org
    Estimation of crossbridge-state during cardiomyocyte beating using second harmonic generation
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    biorxiv.org/content/10.1101/2022.10.13.512034v1
  94. www.biorxiv.org www.biorxiv.org
    Identification of a novel enhancer essential for Satb1 expression in TH2 cells and activated ILC2s.
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    biorxiv.org/content/10.1101/2023.01.03.522551v1
  95. www.biorxiv.org www.biorxiv.org
    Spatial metabolomics for symbiotic marine invertebrates
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    biorxiv.org/content/10.1101/2022.10.05.511040v1
  96. www.biorxiv.org www.biorxiv.org
    MAP4K3 inhibits Sirtuin-1 to repress LKB1-AMPK to promote amino acid dependent activation of mTORC1
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    biorxiv.org/content/10.1101/2021.11.08.467702v2
  97. www.biorxiv.org www.biorxiv.org
    Origin and segregation of the human germline
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    biorxiv.org/content/10.1101/2022.07.06.498671v1
  98. www.biorxiv.org www.biorxiv.org
    Apolipoprotein E intersects with amyloid-β within neurons
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    biorxiv.org/content/10.1101/2022.12.13.520238v1
  99. www.biorxiv.org www.biorxiv.org
    Distant sequence regions of JBP1 contribute to J-DNA binding
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    biorxiv.org/content/10.1101/2023.01.23.525147v1
  100. www.biorxiv.org www.biorxiv.org
    IKBKB reduces huntingtin aggregation by phosphorylating Serine 13 via a non-canonical IKK pathway
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    biorxiv.org/content/10.1101/2022.12.05.519070v1
  101. www.biorxiv.org www.biorxiv.org
    Germinal Centers Convergent Evolution and B cell Recirculation in Human Lymph Nodes
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    biorxiv.org/content/10.1101/2022.11.09.463832v9
  102. Aug 2023
  103. www.biorxiv.org www.biorxiv.org
    NLRP3 controls ATM activation in response to DNA damage.
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    biorxiv.org/content/10.1101/2020.05.12.087015v1
  104. www.biorxiv.org www.biorxiv.org
    The C-terminal tail of CSNAP attenuates the CSN complex
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  105. Jul 2023
  106. www.biorxiv.org www.biorxiv.org
    Comparative membrane proteomics reveals diverse cell regulators concentrated at the nuclear envelope
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    biorxiv.org/content/10.1101/2023.02.13.528342v1
  107. www.biorxiv.org www.biorxiv.org
    Characterizing control of memory CD8 T cell differentiation by BTB-ZF transcription factor Zbtb20
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    biorxiv.org/content/10.1101/2022.08.22.504726v1
  108. www.biorxiv.org www.biorxiv.org
    Extracellular matrix sensing via modulation of orientational order of integrins and F-actin in focal adhesions
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    biorxiv.org/content/10.1101/2022.07.22.501116v2
  109. www.biorxiv.org www.biorxiv.org
    https://biorxiv.org/cgi/content/10.1101/2021.11.16.468777
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    Differential roles of CTP synthetases CTPS1 and CTPS2 in cell proliferation
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    The cytochrome b carboxyl-terminal region is necessary for mitochondrial Complex III assembly
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    biorxiv.org/content/10.1101/2022.11.25.517933v1
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    arfA antisense RNA regulates MscL excretory activity
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    biorxiv.org/content/10.1101/2022.11.21.517365v1
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    Antibody reliability influences observed mRNA-protein correlations in tumour samples
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    N-terminal proteoforms may engage in different protein complexes
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    biorxiv.org/content/10.1101/2023.01.17.524352v2
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    PI3P dependent regulation of cell size and autophagy by phosphatidylinositol 5-phosphate 4-kinase
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    biorxiv.org/content/10.1101/2022.06.18.496676v2
  116. www.biorxiv.org www.biorxiv.org
    Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes.
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    biorxiv.org/content/10.1101/2022.10.14.512296v1
  117. Jun 2023
  118. www.biorxiv.org www.biorxiv.org
    Accurate genotype-based demultiplexing of single cell RNA sequencing samples from non-human animals
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    1. EMBOpress 29 Jun 2023

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    biorxiv.org/content/10.1101/2022.09.22.508993v1
  119. www.biorxiv.org www.biorxiv.org
    Structure-based design and characterization of Parkin activating mutations
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    1. EMBOpress 28 Jun 2023

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    biorxiv.org/content/10.1101/2022.02.22.481412v1
  120. www.biorxiv.org www.biorxiv.org
    Mitochondrial dysfunction rapidly modulates the abundance and thermal stability of cellular proteins
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    1. EMBOpress 28 Jun 2023

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    biorxiv.org/content/10.1101/2022.10.27.514032v1
  121. www.biorxiv.org www.biorxiv.org
    Upf3a is dispensable for nonsense-mediated mRNA decay in mouse pluripotent and somatic cells
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    1. EMBOpress 28 Jun 2023

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    biorxiv.org/content/10.1101/2022.07.04.495064v2
  122. www.biorxiv.org www.biorxiv.org
    Structural insights into ubiquitin chain cleavage by Legionella ovarian tumor deubiquitinases
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    1. EMBOpress 28 Jun 2023

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    biorxiv.org/content/10.1101/2023.01.02.522462v1
  123. www.biorxiv.org www.biorxiv.org
    The pro-inflammatory response to influenza A virus infection is fueled by endothelial cells
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    1. EMBOpress 28 Jun 2023

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    biorxiv.org/content/10.1101/2022.08.19.504520v1
  124. www.biorxiv.org www.biorxiv.org
    Missense variant interaction scanning reveals a critical role of the FERM-F3 domain for tumor suppressor protein NF2 conformation and function
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    1. EMBOpress 28 Jun 2023

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    biorxiv.org/content/10.1101/2022.12.11.519953v2
  125. May 2023
  126. www.biorxiv.org www.biorxiv.org
    BAZ2A-RNA mediated association with TOP2A and KDM1A represses gene expression in prostate cancer
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    1. EMBOpress 31 May 2023

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    biorxiv.org/content/10.1101/2021.07.15.452487v2
  127. www.biorxiv.org www.biorxiv.org
    Recursive splicing discovery using lariats in total RNA sequencing
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    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2022.12.22.521701v1
  128. www.biorxiv.org www.biorxiv.org
    Exploratory Meta-Analysis of Hypoxic Transcriptomes Using a Precise Transcript Reference Sequence Set
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    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2022.05.01.489280v2
  129. www.biorxiv.org www.biorxiv.org
    VEGFR3 modulates brain microvessel branching in a mouse model of 22q11.2 deletion syndrome
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    biorxiv.org/content/10.1101/2022.03.16.484566v1
  130. www.biorxiv.org www.biorxiv.org
    Telescoping bimodal latent Dirichlet allocation to identify expression QTLs across tissues
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    biorxiv.org/content/10.1101/2021.10.27.466156v2
  131. www.biorxiv.org www.biorxiv.org
    RAS and PP2A activities converge on epigenetic gene regulation
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    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2022.05.11.491459v1
  132. www.biorxiv.org www.biorxiv.org
    Functional substitutions of amino acids that differ between GDF11 and GDF8 impact skeletal development and skeletal muscle.
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    biorxiv.org/content/10.1101/2022.05.09.491247v1
  133. www.biorxiv.org www.biorxiv.org
    Gapless provides combined scaffolding, gap filling and assembly correction with long reads
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    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2022.03.08.483466v2
  134. www.biorxiv.org www.biorxiv.org
    Z-Flipon Variants reveal the many roles of Z-DNA and Z-RNA in health and disease
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    1. EMBOpress 24 May 2023

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    biorxiv.org/lookup/doi/10.1101/2023.01.12.523822
  135. www.biorxiv.org www.biorxiv.org
    The value of genotype-specific reference for transcriptome analyses
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    1. EMBOpress 14 May 2023

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    biorxiv.org/content/10.1101/2021.09.14.460213v1
  136. www.biorxiv.org www.biorxiv.org
    Genome-wide CRISPRi screening reveals regulators of Alzheimee's tau pathology shared between exosomal and vesicle-free tau seeds.
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    biorxiv.org/content/10.1101/2022.04.26.489622v1
  137. www.biorxiv.org www.biorxiv.org
    Small non-coding vault RNA1-2 modulate expression of cell membrane proteins through nascent RNA silencing
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    1. EMBOpress 11 May 2023

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    biorxiv.org/content/10.1101/2022.08.12.503724v2
  138. www.biorxiv.org www.biorxiv.org
    LuminoCell: a versatile and affordable luminometer platform for monitoring in-cell luciferase-based reporters
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    1. EMBOpress 11 May 2023

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    biorxiv.org/content/10.1101/2022.01.28.478134v1
  139. Apr 2023
  140. www.biorxiv.org www.biorxiv.org
    Efficient knock-in method enabling lineage tracing in zebrafish
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    1. EMBOpress 12 Apr 2023

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    biorxiv.org/content/10.1101/2022.07.15.500272v1
  141. www.biorxiv.org www.biorxiv.org
    The TUDOR domain of SMN is an H3K79me1 histone mark reader
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    1. EMBOpress 11 Apr 2023

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    biorxiv.org/content/10.1101/2022.10.06.511070v1
  142. www.biorxiv.org www.biorxiv.org
    Preference of CAMSAP3 for microtubules with expanded lattice contributes to stabilization of the minus end
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    1. EMBOpress 11 Apr 2023

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    biorxiv.org/content/10.1101/2022.08.21.504720v2
  143. www.biorxiv.org www.biorxiv.org
    Analysis of context-specific KRAS-effectors (sub)complexes in Caco-2 cells
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    biorxiv.org/content/10.1101/2022.08.15.503960v1
  144. Mar 2023
  145. www.biorxiv.org www.biorxiv.org
    Peroxisomes contribute to intracellular calcium dynamics
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    1. EMBOpress 15 Mar 2023

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    biorxiv.org/content/10.1101/2020.09.02.279174v1
  146. www.biorxiv.org www.biorxiv.org
    An extended DNA-free intranuclear compartment organizes centrosomal microtubules in Plasmodium falciparum
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    biorxiv.org/content/10.1101/2021.03.12.435157v2
  147. www.biorxiv.org www.biorxiv.org
    Non-canonical miRNA-RNA base-pairing impedes tumor suppressor activity of miR-16
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    biorxiv.org/content/10.1101/2021.11.30.470499v1
  148. www.biorxiv.org www.biorxiv.org
    The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation, epithelial repair, and tumor growth
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    biorxiv.org/content/10.1101/2022.04.11.487842v1
  149. www.biorxiv.org www.biorxiv.org
    Stepwise progression of beta-selection during T cell development as revealed by histone deacetylation inhibition
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    biorxiv.org/content/10.1101/2021.10.03.462949v4
  150. www.biorxiv.org www.biorxiv.org
    Lack of peroxisomal catalase affects heat shock response in C. elegans
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    biorxiv.org/content/10.1101/2021.07.13.452156v1
  151. www.biorxiv.org www.biorxiv.org
    Lineage Tracing Reveals Fate Bias and Transcriptional Memory in Human B cells
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    biorxiv.org/content/10.1101/2022.07.14.499766v2
  152. www.biorxiv.org www.biorxiv.org
    Critical roles of ICOS in controlling Foxp3-expressing T follicular cell subsets during early-stage germinal center reactions
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    biorxiv.org/content/10.1101/2021.09.14.460384v2
  153. www.biorxiv.org www.biorxiv.org
    The human MRS2 magnesium binding domain is a regulatory feedback switch for channel activity.
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    biorxiv.org/content/10.1101/2022.09.27.509701v1
  154. www.biorxiv.org www.biorxiv.org
    Activation and inhibition of the C-terminal kinase domain of p90 ribosomal S6 kinases
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    1. EMBOpress 09 Mar 2023

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    biorxiv.org/content/10.1101/2022.02.18.481032v1
  155. www.biorxiv.org www.biorxiv.org
    Segregation of pathways leading to pexophagy
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    1. EMBOpress 09 Mar 2023

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    biorxiv.org/content/10.1101/2022.11.08.515582v1
  156. www.biorxiv.org www.biorxiv.org
    New algorithms for accurate and efficient de-novo genome assembly from long DNA sequencing reads
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    biorxiv.org/content/10.1101/2022.08.30.505891v1
  157. Feb 2023
  158. www.biorxiv.org www.biorxiv.org
    Adenylyl cyclase 9 is auto-stimulated by its isoform-specific carboxyl terminal domain and equipped with paradigm-switching mechanisms.
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    biorxiv.org/content/10.1101/2022.06.05.494885v3
  159. www.biorxiv.org www.biorxiv.org
    Lung macrophages utilize cathepsin K-dependent phagosomal machinery to degrade intracellular collagen
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    biorxiv.org/content/10.1101/2022.05.16.492085v1
  160. www.biorxiv.org www.biorxiv.org
    SorCS1 inhibits amyloid-β binding to neurexin and rescues amyloid-β-induced synaptic pathology
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    biorxiv.org/content/10.1101/2022.07.26.501499v1
  161. www.biorxiv.org www.biorxiv.org
    The GET pathway serves to activate Atg32-mediated mitophagy by ER targeting of the Ppg1-Far complex
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    biorxiv.org/content/10.1101/2021.09.20.461067v1
  162. www.biorxiv.org www.biorxiv.org
    Human RNA Nm-MTase FTSJ1: new tRNA targets and role in the regulation of brain-specific genes.
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    biorxiv.org/content/10.1101/2021.02.06.430044v4
  163. www.biorxiv.org www.biorxiv.org
    A genome-wide CRISPR functional survey of the human phagocytosis molecular machinery
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    biorxiv.org/content/10.1101/2022.09.08.507072v1
  164. www.biorxiv.org www.biorxiv.org
    Epigenetic signals that direct cell type specific interferon beta response in mouse cells
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    biorxiv.org/content/10.1101/2022.02.26.481127v1
  165. www.biorxiv.org www.biorxiv.org
    Convergent evolution and horizontal gene transfer in Arctic Ocean microalgae
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    biorxiv.org/content/10.1101/2021.07.31.454568v1
  166. Jan 2023
  167. www.biorxiv.org www.biorxiv.org
    Structural and functional characterization of TraI from pKM101 reveals basis for DNA processing
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    biorxiv.org/content/10.1101/2022.06.02.494495v2
  168. www.biorxiv.org www.biorxiv.org
    Membrane cholesterol regulates inhibition and substrate transport by the glycine transporter, GlyT2
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    biorxiv.org/content/10.1101/2022.08.31.506132v1
  169. www.biorxiv.org www.biorxiv.org
    SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis.
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    1. EMBOpress 27 Jan 2023

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    biorxiv.org/content/10.1101/2022.02.13.480288v1
  170. www.biorxiv.org www.biorxiv.org
    Epigenetic centromere identity is precisely maintained through DNA replication but is uniquely specified among human cells
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    biorxiv.org/content/10.1101/2022.09.07.506974v1
  171. www.biorxiv.org www.biorxiv.org
    Identifying novel regulators of placental development using time series transcriptomic data and network analyses
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    biorxiv.org/content/10.1101/2022.05.17.492330v1
  172. www.biorxiv.org www.biorxiv.org
    De novo discovery of traits co-occurring with chronic obstructive pulmonary disease
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    biorxiv.org/content/10.1101/2022.07.20.500731v1
  173. www.biorxiv.org www.biorxiv.org
    An isoform-specific function of Cdc42 in regulating mammalian Exo70 during axon formation
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    1. EMBOpress 24 Jan 2023

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    biorxiv.org/content/10.1101/2022.07.01.498448v1
  174. www.biorxiv.org www.biorxiv.org
    Comparative analysis of MERFISH spatial transcriptomics with bulk and single-cell RNA sequencing
    1
    1. EMBOpress 19 Jan 2023

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    biorxiv.org/content/10.1101/2022.03.04.483068v3
  175. www.biorxiv.org www.biorxiv.org
    A synergistic activation of RARb and RARg nuclear receptors restores cell-types specialization during stem cells differentiation by hijacking RARa-controlled program
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    1. EMBOpress 19 Jan 2023

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    biorxiv.org/content/10.1101/2022.05.31.494116v2
  176. www.biorxiv.org www.biorxiv.org
    Nuclear envelope reshaping around the vacuole determines the morphology of the ribosomal DNA
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    1. EMBOpress 18 Jan 2023

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    biorxiv.org/content/10.1101/2021.06.23.449658v1
  177. www.biorxiv.org www.biorxiv.org
    Porcine intestinal innate lymphoid cells and lymphocyte spatial context revealed through single-cell RNA sequencing
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    1. EMBOpress 18 Jan 2023

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    biorxiv.org/content/10.1101/2022.01.09.475571v1
  178. www.biorxiv.org www.biorxiv.org
    Sibling rivalry among the ZBTB transcription factor family: homo vs. heterodimers
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    1. EMBOpress 13 Jan 2023

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    biorxiv.org/content/10.1101/2021.12.17.472994v2
  179. Dec 2022
  180. www.biorxiv.org www.biorxiv.org
    Stage-specific gene and transcript dynamics in human male germ cells
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    1. EMBOpress 30 Dec 2022

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    biorxiv.org/content/10.1101/2022.03.22.485121v1
  181. www.biorxiv.org www.biorxiv.org
    Cdh5-lineage independent origin of dermal lymphatic vessels revealed by temporally restricted lineage tracing
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    1. EMBOpress 17 Dec 2022

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    biorxiv.org/content/10.1101/2022.06.08.495310v1
  182. www.biorxiv.org www.biorxiv.org
    Endoplasmic Reticulum membranes are continuously required to maintain mitotic spindle size and forces
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    1. EMBOpress 16 Dec 2022

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    biorxiv.org/content/10.1101/2022.05.14.491942v1
  183. www.biorxiv.org www.biorxiv.org
    Genome-wide Profiling of Histone Modifications in Plasmodium falciparum using CUT&RUN.
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    1. EMBOpress 16 Dec 2022

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    biorxiv.org/content/10.1101/2022.08.01.502378v2
  184. www.biorxiv.org www.biorxiv.org
    Systematic analysis of ADP-ribose detection reagents and optimisation of sample preparation to detect ADP-ribosylation in vitro and in cells
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    1. EMBOpress 15 Dec 2022

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    biorxiv.org/content/10.1101/2022.02.22.481411v1
  185. www.biorxiv.org www.biorxiv.org
    Drosophila pVALIUM10 TRiP RNAi lines cause undesired silencing of Gateway-based transgenes
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    1. EMBOpress 13 Dec 2022

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    biorxiv.org/content/10.1101/2022.08.12.503771v2
  186. Nov 2022
  187. www.biorxiv.org www.biorxiv.org
    Actin binding domain of Rng2 strongly inhibits actin movement on myosin II HMM through structural changes of actin filaments
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    1. EMBOpress 23 Nov 2022

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    biorxiv.org/content/10.1101/2020.04.14.041046v4
  188. www.biorxiv.org www.biorxiv.org
    Miro GTPase domains regulate assembly of the mitochondrial motor-adaptor complex
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    1. EMBOpress 23 Nov 2022

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    biorxiv.org/content/10.1101/2022.05.13.491728v1
  189. www.biorxiv.org www.biorxiv.org
    Improving the computation efficiency of polygenic risk score modeling: Faster in Julia
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    1. EMBOpress 21 Nov 2022

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    biorxiv.org/content/10.1101/2021.12.27.474263v1
  190. www.biorxiv.org www.biorxiv.org
    Structure of mammalian V-ATPase with the TLDc domain protein mEAK7 bound
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    1. EMBOpress 19 Nov 2022

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    biorxiv.org/content/10.1101/2021.11.03.466369v2
  191. www.biorxiv.org www.biorxiv.org
    Profiling subcellular localization of nuclear-encoded mitochondrial gene products in zebrafish
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    1. EMBOpress 15 Nov 2022

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    biorxiv.org/content/10.1101/2021.12.22.473872v1
  192. Oct 2022
  193. www.biorxiv.org www.biorxiv.org
    https://biorxiv.org/cgi/content/10.1101/2022.03.06.483172
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    1. EMBOpress 28 Oct 2022

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    biorxiv.org/content/10.1101/2022.03.06.483172v1
  194. www.biorxiv.org www.biorxiv.org
    Replication-associated inversions are the dominant form of bacterial chromosome structural variation
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    1. EMBOpress 27 Oct 2022

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    biorxiv.org/content/10.1101/2022.02.15.480581v1
  195. www.biorxiv.org www.biorxiv.org
    Contribution of the Golgi apparatus in morphogenesis of a virus induced cytopathic vacuolar system
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    1. EMBOpress 13 Oct 2022

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    biorxiv.org/content/10.1101/2022.03.14.484265v1
  196. www.biorxiv.org www.biorxiv.org
    Regulation of Liprin-α phase separation by CASK is disrupted by a mutation in its CaM kinase domain
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    1. EMBOpress 13 Oct 2022

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    biorxiv.org/content/10.1101/2022.04.21.489014v1
  197. www.biorxiv.org www.biorxiv.org
    Gain-of-function genetic screens in human cells identify SLC transporters overcoming environmental nutrient restrictions
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    1. EMBOpress 08 Oct 2022

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    biorxiv.org/content/10.1101/2022.04.03.486870v1
  198. www.biorxiv.org www.biorxiv.org
    Synthetic evolution of herbicide resistance using a T7 RNAP-based random DNA base editor
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    1. EMBOpress 08 Oct 2022

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    biorxiv.org/content/10.1101/2021.11.30.470689v1
  199. www.biorxiv.org www.biorxiv.org
    Evaluation of CA repeat arrays as targets for MeCP2 function in the brain
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    1. EMBOpress 08 Oct 2022

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    biorxiv.org/content/10.1101/2022.04.26.489598v2
  200. Sep 2022
  201. www.biorxiv.org www.biorxiv.org
    Meiotic DNA breaks activate a streamlined phospho-signaling response that largely avoids protein level changes
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    1. EMBOpress 27 Sep 2022

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    biorxiv.org/content/10.1101/2022.02.24.481857v1
  202. www.biorxiv.org www.biorxiv.org
    Human gene function publications that describe wrongly identified nucleotide sequence reagents are unacceptably frequent within the genetics literature
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    1. EMBOpress 13 Sep 2022

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    biorxiv.org/lookup/doi/10.1101/2021.07.29.453321
  203. Aug 2022
  204. www.biorxiv.org www.biorxiv.org
    Decreasing pdzd8-mediated mitochondrial-ER contacts in neurons improves fitness by increasing mitophagy
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    1. EMBOpress 31 Aug 2022

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    biorxiv.org/content/10.1101/2020.11.14.382861v1
  205. www.biorxiv.org www.biorxiv.org
    Islet Gene View - a tool to facilitate islet research
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    1. EMBOpress 19 Aug 2022

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    biorxiv.org/content/10.1101/435743v3
  206. www.biorxiv.org www.biorxiv.org
    Resolution of the curse of dimensionality in single-cell RNA sequencing data analysis
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    1. EMBOpress 19 Aug 2022

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    biorxiv.org/content/10.1101/2022.05.02.490246v1
  207. www.biorxiv.org www.biorxiv.org
    CFTR modulator response measurements in subjects with cystic fibrosis using 2D differentiated nasal epithelia converted into spheroids
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    1. EMBOpress 18 Aug 2022

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    biorxiv.org/content/10.1101/2021.07.20.453105v2
  208. www.biorxiv.org www.biorxiv.org
    A minimal hepatocyte growth factor mimic acting as a powerful agonist of the MET receptor tyrosine kinase for regeneration of epithelial tissues and organs.
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    1. EMBOpress 17 Aug 2022

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    biorxiv.org/content/10.1101/2020.07.20.212654v3
  209. www.biorxiv.org www.biorxiv.org
    Drosophila insulator proteins exhibit in-vivo liquid-liquid phase separation properties
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    1. EMBOpress 11 Aug 2022

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    biorxiv.org/content/10.1101/2022.05.27.493687v1
  210. www.biorxiv.org www.biorxiv.org
    ScRNA-seq Expression of APOC2 and IFI27 Identifies Four Families of Alveolar Macrophage Superclusters in Cystic Fibrosis and Healthy BALF
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    biorxiv.org/content/10.1101/2022.01.30.478325v3
  211. www.biorxiv.org www.biorxiv.org
    ERK2 MAP kinase regulates SUFU binding by multisite phosphorylation of GLI1
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    biorxiv.org/content/10.1101/2021.12.22.473898v2
  212. Jul 2022
  213. www.biorxiv.org www.biorxiv.org
    LncRNA RUS shapes the gene expression program towards neurogenesis
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    biorxiv.org/content/10.1101/2022.02.17.480853v1
  214. Jun 2022
  215. www.biorxiv.org www.biorxiv.org
    Negative curvature-promoting lipids instruct nuclear ingression of low autophagic potential vacuoles
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    biorxiv.org/content/10.1101/2021.06.26.450031v1
  216. www.biorxiv.org www.biorxiv.org
    OXSR1 inhibits inflammasome activation by limiting potassium efflux during mycobacterial infection
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    biorxiv.org/content/10.1101/2021.04.21.440692v1
  217. www.biorxiv.org www.biorxiv.org
    Genetic and compound screens uncover factors modulating cancer cell response to indisulam
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    biorxiv.org/content/10.1101/2021.12.20.473451v1
  218. www.biorxiv.org www.biorxiv.org
    Map7D2 and Map7D1 facilitate microtubule stabilization through distinct mechanisms to control cell motility and neurite outgrowth.
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    1. EMBOpress 01 Jun 2022

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    biorxiv.org/content/10.1101/2021.10.27.466197v3
  219. May 2022
  220. www.biorxiv.org www.biorxiv.org
    Molecular insights into RNA recognition and gene regulation by the TRIM-NHL protein Mei-P26
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    biorxiv.org/content/10.1101/2021.09.20.461029v1
  221. Apr 2022
  222. www.biorxiv.org www.biorxiv.org
    Tricalbin proteins regulate plasma membrane phospholipid homeostasis
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    biorxiv.org/content/10.1101/2021.06.04.447076v1
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    Polycomb Group Ring Finger Protein 6 suppresses Myc-induced lymphomagenesis
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    biorxiv.org/content/10.1101/2021.12.02.470967v1
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    Quantitative analysis of nuclear pore complex organization in Schizosaccharomyces pombe
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    biorxiv.org/content/10.1101/2021.08.11.455278v1
  225. www.biorxiv.org www.biorxiv.org
    TET2-mediated epigenetic reprogramming of breast cancer cells impairs lysosome biogenesis
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    1. EMBOpress 22 Apr 2022

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    biorxiv.org/content/10.1101/2021.10.27.466063v1
  226. www.biorxiv.org www.biorxiv.org
    https://biorxiv.org/cgi/content/10.1101/2021.10.18.464926
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    biorxiv.org/content/10.1101/2021.10.18.464926v1
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    Conserved exchange of paralog proteins during neuronal differentiation
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    biorxiv.org/content/10.1101/2021.07.22.453347v1
  228. Mar 2022
  229. www.biorxiv.org www.biorxiv.org
    AGO1 regulates major satellite transcripts and H3K9me3 distribution at pericentromeric regions in mESCs
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    biorxiv.org/content/10.1101/2021.07.26.453733v2
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    GROWTH-RATE DEPENDENT AND NUTRIENT-SPECIFIC GENE EXPRESSION RESOURCE ALLOCATION IN FISSION YEAST
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    1. EMBOpress 22 Mar 2022

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    biorxiv.org/content/10.1101/2021.03.16.435638v1
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    The expression of essential selenoproteins during zebrafish development requires SECIS binding protein 2-like
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    biorxiv.org/content/10.1101/2021.11.01.466845v1
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    Stress-induced tyrosine phosphorylation of RtcB modulates IRE1 activity and signaling outputs.
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    biorxiv.org/content/10.1101/2020.03.02.972950v5
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    ETV2 regulates PARP-1 binding protein to induce ER stress-mediated cell death in tuberin-deficient cells
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    biorxiv.org/content/10.1101/2021.11.08.467714v1
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    Quantitative Profiling of Adaptation to Cyclin E Overproduction
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    biorxiv.org/content/10.1101/2021.07.26.453751v3