all of these clinical issues connect to issues w/ traditional drug development

what are these levels? basic screening to clinical trials?

Yeah, I remember this. takes so mych longer than you would intitially expect

Didn't know about C.auris that was new info to me

Using AI to combat it is so cool!

basic membrane functions

not as familiar w/ these AB virulence factors

QS can dictate which EPS components are excreted and what gene expression is up/down regulated to maintain biofilm

biofilms would prevent AMPs from accessing the membrane

more details on these methods?

a variety of interacting factors impact antimicrobial capabilities

'nonlinear interactions' is thrown around often; just a behavior that causes exponential or multi-faceted consequences?

maybe familiar? random forests use decision trees -> like a flow chart?

are these all bad for AMP effectiveness?

vaguely familiar; just looking for specific qualities? generating specific qualities?

not very familiar with these; have heard of de novo peptide design and selectivity/stability considerations

familiar/can explain this in the context of traditional drug development; translational barriers are significanrt

for - future project - building a model to explain spacetime using Active Inference - Donald Hoffman - use Active Inference to minimise surprise using Markov chains - this model assumes consciousness is fundamental - this is going to be a model of intelligence based entirely from a model which takes consciousness as fundamental. - it goes back to game theory again. - back to the idea of a simulation - If you're able to create a piece of software that - is able to replicate and - is built on the fundamentals of consciousness. - Then it's potentially, it's going to think it's conscious

For a thunk, do def lazyHello : Thunk String := fun () => "world" -- abbrev Thunk (α : Type) := Unit → α -- built-in

for - quote - no evolutionary history explains form and behavior - Michael Levin

observation - evolution alone is insufficient to explain life - These novel, artificial life forms behave in novel emergent ways, there is no natural selection at play here

for - Youtube - Techdenkers: Anil Seth - Exploring the Possibility of Artificcial consciousness - out of body experience - Anil Seth - good point - how do you explain seeing without eyes?

Certainly! Let's break down the provided code snippets:

1. What is it and why is it used?

In Mongoose, a schema is a blueprint for defining the structure of documents within a collection. When you define a schema, you can also attach methods to it. These methods become instance methods, meaning they are available on the individual documents (instances) created from that schema.

Instance methods are useful for encapsulating functionality related to a specific document or model instance. They allow you to define custom behavior that can be executed on a specific document. In the given example, the findSimilarTypes method is added to instances of the Animal model, making it easy to find other animals of the same type.

2. Syntax:

Using methods object directly in the schema options:

javascript const animalSchema = new Schema( { name: String, type: String }, { methods: { findSimilarTypes(cb) { return mongoose.model('Animal').find({ type: this.type }, cb); } } } );

Using methods object directly in the schema:

javascript animalSchema.methods.findSimilarTypes = function(cb) { return mongoose.model('Animal').find({ type: this.type }, cb); };

Using Schema.method() helper:

javascript animalSchema.method('findSimilarTypes', function(cb) { return mongoose.model('Animal').find({ type: this.type }, cb); });

3. Explanation in Simple Words with Examples:

Why it's Used:

Imagine you have a collection of animals in your database, and you want to find other animals of the same type. Instead of writing the same logic repeatedly, you can define a method that can be called on each animal instance to find similar types. This helps in keeping your code DRY (Don't Repeat Yourself) and makes it easier to maintain.

Example:

```javascript const mongoose = require('mongoose'); const { Schema } = mongoose;

// Define a schema with a custom instance method const animalSchema = new Schema({ name: String, type: String });

// Add a custom instance method to find similar types animalSchema.methods.findSimilarTypes = function(cb) { return mongoose.model('Animal').find({ type: this.type }, cb); };

// Create the Animal model using the schema const Animal = mongoose.model('Animal', animalSchema);

// Create an instance of Animal const dog = new Animal({ type: 'dog', name: 'Buddy' });

// Use the custom method to find similar types dog.findSimilarTypes((err, similarAnimals) => { console.log(similarAnimals); }); ```

In this example, findSimilarTypes is a custom instance method added to the Animal schema. When you create an instance of the Animal model (e.g., a dog), you can then call findSimilarTypes on that instance to find other animals with the same type. The method uses the this.type property, which refers to the type of the current animal instance. This allows you to easily reuse the logic for finding similar types across different instances of the Animal model.

Then, the article quote the U.S. Constitution, Article I section 8, clause 8, and then explains that, in the 18th century, this constitutional law gave the congress the power to grant exclusive rights to authors and inventors for their work, in order to boost creativity and innovation in the USA (U.S. Const., 1787). Later, the article claims that in the 1975, the U.S. Constitution, Article I section 8, clause 8 keep having the purpose of fostering innovation and creativity in the society, throughout economic incentive. Subsequently, the article supports this statement by quoting the law "Twentieth Century Music Corp. v. Aiken," which was created in 1975 with the purpose of boosting creativity and innovation in society throughout the economic incentive of assuring that creators receive a payment for their intellectual property that equates to the cost of producing it.

"I didn't fully understand it at the time, but throughout my time as a freshman at Boston College I've realized that I have the power to alter myself for the better and broaden my perspective on life. For most of my high school experience, I was holding to antiquated thoughts that had an impact on the majority of my daily interactions. Throughout my life, growing up as a single child has affected the way am in social interactions. This was evident in high school class discussions, as I did not yet have the confidence to be talkative and participate even up until the spring term of my senior year."

Interphase

For this standard, students would have to read a variety of poems, plays and prose to understand the structural differences. Then the students must use the structural knowledge to properly write and speak about poems and plays. A good play for this standard would be Annie and a good collections of poems to understand structure would be from poet Roald Dahl.

How will the results be improved and in what way will the community be better served?

I expect you explain how later in the document and provide examples, but to strengthen the intro and capture your readers give the a teaser of what's to come if they continue reading.