both replication is dependent on the living cell and the function of the proteins is dependent on the living cell. Neither automatically follow from the DNA alone
for - key insight - cell replication AND function of proteins are both dependent on the living cell. Neither follow from DNA alone - Denis Noble
Enzymes are proteins which catalyze biochemical reactions
Enzymes are to SUBSTRATES As Receptors are to LIGANDS
folds up very specifically into a three-dimensional structure
Tertiary Structure: Characteristics: - 1+ Binding pockets to bind other molecules - Folded Structure - Functional Groups = Determines what the protein DO.
substrates
How do enzymes react> they need a substrate to bind to an active site (pocket) where the rxn will take place.
amino acid is incorporated into a protein it loses a molecule of water and what remains is called a residue of the original amino acid
What reaction occurs when creating a polymer? When another amino acid chain attaches together, it forms a peptide bond through a dehydration synthesis reaction of which leaves a residue of the original amino acid.
coded for by an organism's DNA
What determines the protein sequence? The DNA during replication determines what type of protein (classified as 50+ amino acids) is formed. aka PROTEIN SYNTHESIS or TRANSLATION
amino acid side chains
Why are each side chain unique? BECAUSE they each have a functional group !
a stop-transfer sequence (a hydrophobic domain within the polypeptide chain) traps the protein in the fatty acid interior
அதிலிருக்கும் 18 அமினோ அமிலங்கள், முட்டை, பால், இறைச்சிக்கு இணையான புரத சத்துகளை நம் உடலுக்குக் கொடுக்கக்கூடிய திறன் கொண்டது என்பது உங்களுக்குத் தெரியுமா
histone acetylation
Allows for DNA binding proteins to interact with sites to activate gene transcription and alters the accessibility of chromatin.
packing
The process of putting genetic material and encapsulating it with a coat of proteins.
1169 proteins
mCherry2 might have decreased cytotoxicity in E. coli.
compared to mCherry
Separating Golgi proteins from cis to trans reveals underlying properties of cisternal localization
Check out the peer review report here http://www.plantcell.org/content/plantcell/suppl/2019/07/03/tpc.19.00081.DC2/tpc19.00081.PeerReviewReport.pdf
Global protein acetylation
See for example "Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions" by Chunaram Choudhary, Chanchal Kumar, Florian Gnad, Michael L. Nielsen, Michael Rehman, Tobias C. Walther, Jesper V. Olsen, Matthias Mann, Science, 14 Aug 2009, which demonstrates that "the regulatory scope of lysine acetylation is broad and comparable with that of other major posttranslational modifications".