1,108 Matching Annotations
  1. Jun 2023
  2. www.biorxiv.org www.biorxiv.org
    A case of mistaken identity: structurally similar ligand inhibits Thymidylate Kinase causing reversible filamentation of E. coli
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    1. EMBOpress 10 Jun 2023

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    biorxiv.org/content/10.1101/738823v4
  3. www.biorxiv.org www.biorxiv.org
    Highly multiplexed quantitative phosphosite assay for biology and preclinical studies
    1
    1. EMBOpress 10 Jun 2023

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    biorxiv.org/content/10.1101/2020.12.08.415281v1
  4. www.biorxiv.org www.biorxiv.org
    The histone methyltransferase DOT1L regulates chromatin reorganization and gene expression during the postmeiotic differentiation of male germ cells
    1
    1. EMBOpress 10 Jun 2023

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    biorxiv.org/content/10.1101/2022.10.17.512530v2
  5. www.biorxiv.org www.biorxiv.org
    Age-dependent lipid droplet-rich microglia worsen stroke outcome in old mice
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    1. EMBOpress 06 Jun 2023

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    biorxiv.org/content/10.1101/2022.03.14.484305v1
  6. www.biorxiv.org www.biorxiv.org
    Systems-level transcriptional regulation of Caenorhabditis elegans metabolism
    1
    1. EMBOpress 02 Jun 2023

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    biorxiv.org/content/10.1101/2022.11.08.515576v1
  7. May 2023
  8. www.biorxiv.org www.biorxiv.org
    BAZ2A-RNA mediated association with TOP2A and KDM1A represses gene expression in prostate cancer
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    1. EMBOpress 31 May 2023

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    biorxiv.org/content/10.1101/2021.07.15.452487v2
  9. www.biorxiv.org www.biorxiv.org
    Recursive splicing discovery using lariats in total RNA sequencing
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    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2022.12.22.521701v1
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    Exploratory Meta-Analysis of Hypoxic Transcriptomes Using a Precise Transcript Reference Sequence Set
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    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2022.05.01.489280v2
  11. www.biorxiv.org www.biorxiv.org
    VEGFR3 modulates brain microvessel branching in a mouse model of 22q11.2 deletion syndrome
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    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2022.03.16.484566v1
  12. www.biorxiv.org www.biorxiv.org
    Telescoping bimodal latent Dirichlet allocation to identify expression QTLs across tissues
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    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2021.10.27.466156v2
  13. www.biorxiv.org www.biorxiv.org
    RAS and PP2A activities converge on epigenetic gene regulation
    1
    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2022.05.11.491459v1
  14. www.biorxiv.org www.biorxiv.org
    Functional substitutions of amino acids that differ between GDF11 and GDF8 impact skeletal development and skeletal muscle.
    1
    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2022.05.09.491247v1
  15. www.biorxiv.org www.biorxiv.org
    Gapless provides combined scaffolding, gap filling and assembly correction with long reads
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    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2022.03.08.483466v2
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    A quantitative fluorescence-based approach to study mitochondrial protein import
    1
    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2022.10.10.511594v1
  17. www.biorxiv.org www.biorxiv.org
    Ubiquitination occurs in the mitochondrial matrix by eclipsed components of the ubiquitin machinery
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    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2022.07.10.499450v2
  18. www.biorxiv.org www.biorxiv.org
    The transcriptional regulator Sin3A balances IL-17A and Foxp3 expression in primary CD4 T cells
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    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2022.04.19.488789v1
  19. www.biorxiv.org www.biorxiv.org
    Inhibition of the ATM kinase rescues planarian regeneration after lethal radiation
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    1. EMBOpress 26 May 2023

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    biorxiv.org/content/10.1101/2022.09.28.509579v1
  20. www.biorxiv.org www.biorxiv.org
    Ubx5-Cdc48 assists the protease Wss1 at DNA-protein crosslink sites in yeast
    1
    1. EMBOpress 25 May 2023

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    biorxiv.org/content/10.1101/2022.05.30.493988v1
  21. www.biorxiv.org www.biorxiv.org
    Molecular and cognitive signatures of ageing partially restored through synthetic delivery of IL2 to the brain
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    1. EMBOpress 25 May 2023

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    biorxiv.org/content/10.1101/2022.03.01.482519v1
  22. www.biorxiv.org www.biorxiv.org
    Nirmatrelvir treatment blunts the development of antiviral adaptive immune responses in SARS-CoV-2 infected mice
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    1. EMBOpress 25 May 2023

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    biorxiv.org/content/10.1101/2022.11.22.517465v2
  23. www.biorxiv.org www.biorxiv.org
    Endothelial FOXC1 and FOXC2 promote intestinal regeneration after ischemia-reperfusion injury
    1
    1. EMBOpress 25 May 2023

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    biorxiv.org/content/10.1101/2022.03.03.482713v2
  24. www.biorxiv.org www.biorxiv.org
    eIF3 mRNA selectivity profiling reveals eIF3k as a cancer-relevant regulator of ribosome content
    1
    1. EMBOpress 25 May 2023

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    biorxiv.org/content/10.1101/2022.08.28.505560v2
  25. www.biorxiv.org www.biorxiv.org
    Z-Flipon Variants reveal the many roles of Z-DNA and Z-RNA in health and disease
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    1. EMBOpress 24 May 2023

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    biorxiv.org/lookup/doi/10.1101/2023.01.12.523822
  26. www.biorxiv.org www.biorxiv.org
    A stimulus-contingent positive feedback loop enables IFN-β dose-dependent activation of pro-inflammatory genes
    1
    1. EMBOpress 24 May 2023

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    biorxiv.org/lookup/doi/10.1101/2022.08.11.503561
  27. www.biorxiv.org www.biorxiv.org
    Automated assembly of molecular mechanisms at scale from text mining and curated databases
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    1. EMBOpress 24 May 2023

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    biorxiv.org/lookup/doi/10.1101/2022.08.30.505688
  28. www.biorxiv.org www.biorxiv.org
    Subcutaneous BCG vaccination protects against streptococcal pneumonia via regulating innate immune responses in the lung
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    1. EMBOpress 24 May 2023

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    biorxiv.org/lookup/doi/10.1101/2022.09.29.510220
  29. www.biorxiv.org www.biorxiv.org
    Transcription factor expression is the main determinant of variability in gene co-activity
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    1. EMBOpress 24 May 2023

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    biorxiv.org/lookup/doi/10.1101/2022.10.11.511770
  30. www.biorxiv.org www.biorxiv.org
    FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors
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    1. EMBOpress 24 May 2023

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    biorxiv.org/lookup/doi/10.1101/2022.10.12.511867
  31. www.biorxiv.org www.biorxiv.org
    Mapping single-cell responses to population-level dynamics during antibiotic treatment
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    1. EMBOpress 24 May 2023

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    biorxiv.org/lookup/doi/10.1101/2022.11.18.517151
  32. www.biorxiv.org www.biorxiv.org
    ROR1 plays a critical role in pancreatic tumor-initiating cells with a partial EMT signature.
    1
    1. EMBOpress 19 May 2023

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    biorxiv.org/content/10.1101/2022.07.13.499868v1
  33. www.biorxiv.org www.biorxiv.org
    The piRNA pathway sustains adult neurogenesis by repressing protein synthesis
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    1. EMBOpress 17 May 2023

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    biorxiv.org/content/10.1101/2020.09.15.297739v2
  34. www.biorxiv.org www.biorxiv.org
    DASH/Dam1 complex mutants stabilize ploidy by weakening kinetochore-microtubule attachments
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    1. EMBOpress 16 May 2023

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    biorxiv.org/content/10.1101/2022.09.28.509901v1
  35. www.biorxiv.org www.biorxiv.org
    The value of genotype-specific reference for transcriptome analyses
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    1. EMBOpress 14 May 2023

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    biorxiv.org/content/10.1101/2021.09.14.460213v1
  36. www.biorxiv.org www.biorxiv.org
    Genome-wide CRISPRi screening reveals regulators of Alzheimee's tau pathology shared between exosomal and vesicle-free tau seeds.
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    1. EMBOpress 14 May 2023

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    biorxiv.org/content/10.1101/2022.04.26.489622v1
  37. www.biorxiv.org www.biorxiv.org
    Small non-coding vault RNA1-2 modulate expression of cell membrane proteins through nascent RNA silencing
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    1. EMBOpress 11 May 2023

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    biorxiv.org/content/10.1101/2022.08.12.503724v2
  38. www.biorxiv.org www.biorxiv.org
    LuminoCell: a versatile and affordable luminometer platform for monitoring in-cell luciferase-based reporters
    1
    1. EMBOpress 11 May 2023

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    biorxiv.org/content/10.1101/2022.01.28.478134v1
  39. www.biorxiv.org www.biorxiv.org
    Caspase-dependent activation of Hedgehog-signalling sustains proliferation and differentiation of ovarian somatic stem cells.
    1
    1. EMBOpress 05 May 2023

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    biorxiv.org/content/10.1101/722330v3
  40. Apr 2023
  41. www.biorxiv.org www.biorxiv.org
    TOR acts as metabolic gatekeeper for auxin-dependent lateral root initiation in Arabidopsis thaliana
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    1. EMBOpress 28 Apr 2023

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    biorxiv.org/content/10.1101/2022.03.29.486207v2
  42. www.biorxiv.org www.biorxiv.org
    β-catenin activity induces an RNA biosynthesis program promoting therapy resistance in T Acute Lymphoblastic Leukemia
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    1. EMBOpress 27 Apr 2023

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    biorxiv.org/content/10.1101/2022.07.07.499249v1
  43. www.biorxiv.org www.biorxiv.org
    UBAP2L-dependent coupling of PLK1 localization and stability during mitosis
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    1. EMBOpress 27 Apr 2023

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    biorxiv.org/content/10.1101/2022.10.24.513562v2
  44. www.biorxiv.org www.biorxiv.org
    An RNA-binding switch drives ribosome biogenesis and tumorigenesis downstream of RAS oncogene
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    1. EMBOpress 25 Apr 2023

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    biorxiv.org/content/10.1101/2021.12.16.472890v3
  45. www.biorxiv.org www.biorxiv.org
    Combined measurements of proteome and cell turnover reveal the influences of tissue context and pathological aging on protein and organelle lifetimes
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    1. EMBOpress 20 Apr 2023

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    biorxiv.org/content/10.1101/2022.04.24.488979v3
  46. www.biorxiv.org www.biorxiv.org
    Cell-extrinsic autophagy in mature adipocytes regulates anti-inflammatory response to intestinal tissue injury through lipid mobilization
    1
    1. EMBOpress 19 Apr 2023

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    biorxiv.org/content/10.1101/2021.10.25.465200v2
  47. www.biorxiv.org www.biorxiv.org
    Deregulations of miR-1 and its target Multiplexin promote dilated cardiomyopathy associated with myotonic dystrophy type 1
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    1. EMBOpress 13 Apr 2023

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    biorxiv.org/content/10.1101/2022.09.06.506816v1
  48. www.biorxiv.org www.biorxiv.org
    Efficient knock-in method enabling lineage tracing in zebrafish
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    1. EMBOpress 12 Apr 2023

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    biorxiv.org/content/10.1101/2022.07.15.500272v1
  49. www.biorxiv.org www.biorxiv.org
    An innovative hematopoietic stem cell gene therapy approach benefits CLN1 disease in the mouse model
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    1. EMBOpress 12 Apr 2023

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    biorxiv.org/content/10.1101/2022.03.03.482460v1
  50. www.biorxiv.org www.biorxiv.org
    Morphofunctional changes at the active zone during synaptic vesicle exocytosis
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    1. EMBOpress 12 Apr 2023

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    biorxiv.org/content/10.1101/2022.03.07.483217v2
  51. www.biorxiv.org www.biorxiv.org
    The TUDOR domain of SMN is an H3K79me1 histone mark reader
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    1. EMBOpress 11 Apr 2023

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    biorxiv.org/content/10.1101/2022.10.06.511070v1
  52. www.biorxiv.org www.biorxiv.org
    Preference of CAMSAP3 for microtubules with expanded lattice contributes to stabilization of the minus end
    1
    1. EMBOpress 11 Apr 2023

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    biorxiv.org/content/10.1101/2022.08.21.504720v2
  53. www.biorxiv.org www.biorxiv.org
    Analysis of context-specific KRAS-effectors (sub)complexes in Caco-2 cells
    1
    1. EMBOpress 11 Apr 2023

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    An extended DNA-free intranuclear compartment organizes centrosomal microtubules in Plasmodium falciparum
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    The blood vasculature instructs lymphatics patterning in a SOX7-dependent manner
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    TSC2 regulates tumor susceptibility to TRAIL-mediated T cell killing by orchestrating mTOR signaling
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    Transient ribosome slowdown at the decoding step triggers mRNA degradation independent of Znf598 in zebrafish
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    Human RNA Nm-MTase FTSJ1: new tRNA targets and role in the regulation of brain-specific genes.
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    A genome-wide CRISPR functional survey of the human phagocytosis molecular machinery
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    Epigenetic signals that direct cell type specific interferon beta response in mouse cells
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    CDK9 and PP2A regulate the link between RNA polymerase II transcription termination and RNA maturation.
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    Constricted migration contributes to persistent 3D genome structure changes associated with an invasive phenotype in melanoma cells
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    NuRD independent Mi-2 activity represses ectopic gene expression during neuronal maturation.
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    Evolution of genome fragility enables microbial division of labor
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    Convergent evolution and horizontal gene transfer in Arctic Ocean microalgae
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    A molecular mechanism by which amyloid-β induces transcriptional inactivation of CREB in Alzheimer's Disease
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  117. Jan 2023
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    A toolbox for systematic discovery of stable and transient protein interactors in baker's yeast
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    Structural and functional characterization of TraI from pKM101 reveals basis for DNA processing
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    Membrane cholesterol regulates inhibition and substrate transport by the glycine transporter, GlyT2
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    Pan-Cancer landscape of protein activities identifies drivers of signalling dysregulation and patient survival
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    SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis.
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    Plasma membrane topography governs the three-dimensional dynamic localization of IgM B cell receptor clusters
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    Epigenetic centromere identity is precisely maintained through DNA replication but is uniquely specified among human cells
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    Identifying novel regulators of placental development using time series transcriptomic data and network analyses
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    De novo discovery of traits co-occurring with chronic obstructive pulmonary disease
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    An isoform-specific function of Cdc42 in regulating mammalian Exo70 during axon formation
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    CDK8 and CDK19 act redundantly to control the CFTR pathway in the intestinal epithelium
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    Adaptation of bacterial proteome reveals a key role of the cell envelope in starvation survival
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    Condensin pinches a short negatively supercoiledDNA loop during each round of ATP usage
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    Comparative analysis of MERFISH spatial transcriptomics with bulk and single-cell RNA sequencing
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    A synergistic activation of RARb and RARg nuclear receptors restores cell-types specialization during stem cells differentiation by hijacking RARa-controlled program
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    NOTCH3 active immunotherapy reduces NOTCH3 deposition in brain capillaries in a CADASIL mouse model
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    Nuclear envelope reshaping around the vacuole determines the morphology of the ribosomal DNA
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    Porcine intestinal innate lymphoid cells and lymphocyte spatial context revealed through single-cell RNA sequencing
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    Sibling rivalry among the ZBTB transcription factor family: homo vs. heterodimers
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  137. Dec 2022
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    Stage-specific gene and transcript dynamics in human male germ cells
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    Cdh5-lineage independent origin of dermal lymphatic vessels revealed by temporally restricted lineage tracing
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    Adaptation delay causes a burst of mutations in bacteria responding to oxidative stress
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    Endoplasmic Reticulum membranes are continuously required to maintain mitotic spindle size and forces
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    Genome-wide Profiling of Histone Modifications in Plasmodium falciparum using CUT&RUN.
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    When Yeast Cells Change their Mind: Cell Cycle 'Start' is Reversible under Starvation
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    Systematic analysis of ADP-ribose detection reagents and optimisation of sample preparation to detect ADP-ribosylation in vitro and in cells
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    Structural and biochemical basis of FANCI-FANCD2 interdependent ubiquitination
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    Specific N-glycans regulate an extracellular adhesion complex during somatosensory dendrite patterning
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    The dengue virus NS1 protein conveys pro-inflammatory signals by docking onto human high-density lipoproteins
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    Drosophila pVALIUM10 TRiP RNAi lines cause undesired silencing of Gateway-based transgenes
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    Cue-specific remodeling of the neuronal transcriptome through intron retention programs
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    Dissecting the co-transcriptome landscape of plants and microbiota members
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    Epithelial-mesenchymal transition is the main driver of intrinsic metabolism in cancer cell lines
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    The extracellular matrix fibulin 7 maintains epidermal stem cell heterogeneity during skin aging
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    The AAA-ATPase Atad1 and its partners promote degradation of desmin intermediate filaments in muscle
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    Live-cell chromosome dynamics in Arabidopsis thaliana reveals increased chromatin mobility in response to DNA damage
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    Actin binding domain of Rng2 strongly inhibits actin movement on myosin II HMM through structural changes of actin filaments
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    The Toll pathway mediates Drosophila resilience to Aspergillus mycotoxins through specific Bomanins
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    HEAT SHOCK FACTOR BINDING PROTEIN limits meiotic crossovers by repressing HEI10 transcription
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    biorxiv.org/content/10.1101/2021.10.04.462880v1
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    Structural mechanism underpinning Thermus oshimai Pif1-mediated G-quadruplex unfolding
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    1. EMBOpress 21 Nov 2022

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      PeerReviewed EMBOPress EMBO reports biophysics
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    biorxiv.org/content/10.1101/2021.08.24.457465v1
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    ALS-linked KIF5A ΔExon27 mutant causes neuronal toxicity through gain of function
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    biorxiv.org/content/10.1101/2022.03.05.483071v1