6 Matching Annotations
  1. Dec 2018
    1. such personal advantages

      Another conceited man along the lines of Persuasion's Sir Elliot.

    2. volume of Camilla

      Charlotte has similar reading tastes to Catherine (Northanger Abbey).

  2. Oct 2017
    1. classic T-cell activation by pMHC-TCR interaction and the BiTE® mode of action share several features: (i) Formation of BiTE®-mediated cytolytic synapses structurally resembles normal immunologic synapses. (ii) Induction of full-blown T-cell activation utilizes common signal transduction pathways. This leads to upregulation of activation markers, cytokine release, and proliferation, and is strictly target cell-dependent. (iii) Redirected lysis of target cells is mediated by induction of apoptosis as evidenced by perforin and granzyme B release, caspase 3/7 activation, PARP cleavage, DNA fragmentation, and membrane blebbing and perforation. (iv) T cells can adopt a serial lysis mode to sequentially kill multiple target cells.

      similarities between adaptive immune response and bite

  3. Feb 2017
    1. sannah Wesley, who had led large prayer meetings in their home when her Anglican priest husband was absent. W

      Beginning with Margaret Fell in the late seventeenth century, Quaker women were among the first lo speak in public on social issues, Similar behavior between the two woman of allowing meetings in their homes. Only difference was that Margaret ended up in prison.

    1. we’re both so focused on what the other is saying or doing that’s wrong that we barely hear anything else. There may have been a time when we might listen to what the other has to say politely, but those days are long gone.

      I believe this statement can sum up many if not almost all of the arguments we have with friends. We just focus on what they are doing wrong or saying wrong at the moment that we forget how much we actually have in common thus making us FRIENDS. I believe the author puts it greatly that the time to be polite is long gone. Could this because of the growing trend of social media?