37 Matching Annotations
  1. Apr 2026
    1. Treatment of superficial vein reflux (see Varicose Veins, above) has been shown to decrease the recurrence rate of venous ulcers. Where there is substantial obstruction of the femoral or popliteal deep venous system, superficial varicosities supply the venous return and should not be removed.

      Failure of venous insufficiency ulcerations to heal is most often due to inconsistent use of first-line treatment methods. Ongoing control of edema is essential to prevent recurrent ulceration; the use of compression stockings following ulcer healing is critical, with recurrence rates 2–20 times higher if compression stockings are not used

      Duplex ultrasound evaluation should assess blood flow direction, venous reflux, and venous obstruction, and include examination of the deep venous system, great saphenous vein (GSV), small saphenous vein (SSV) and its thigh extension (Giacomini vein), accessory saphenous veins, and perforating veins. Venography is recommended primarily in patients with post-thrombotic disease, especially when intervention is planned, as it provides greater anatomic detail than duplex ultrasonograph The examination also identifies patterns of disease that have treatment implications. Axial reflux is defined as uninterrupted retrograde flow from groin to calf and can occur in either superficial or deep systems. [4] Junctional reflux is limited to the saphenofemoral or saphenopopliteal junction, while segmental reflux occurs in a portion of a truncal vein. [4] Understanding whether reflux originates from superficial junctions versus deep venous incompetence fundamentally changes treatment planning, as superficial disease is amenable to ablation while deep disease typically requires conservative management Management of secondary varicose veins from post-thrombotic syndrome (PTS) is fundamentally different and more challenging. Compression therapy, lifestyle modifications, and symptom management form the cornerstone of PTS treatment. [4-8] Elastic compression stockings (20-30 mm Hg), leg elevation, weight loss, and exercise constitute the primary therapeutic approach Endovascular interventions for PTS—including percutaneous transluminal venoplasty and stenting—are reserved for select patients with significant iliofemoral obstruction who have failed conservative management. [7] These procedures require careful patient selection and standardized criteria. The role of superficial venous ablation in PTS patients with concomitant superficial reflux remains controversial and should be approached cautiously, as the underlying deep venous pathology may limit benefit

    Tags

    Annotators

    URL

  2. Jun 2025
    1. what unification uh allowed us to do with a uh a good theory of electromagnetism is to say that first of all all of these are actually uh examples of the same underlying phenomenon. So we were able to put them on one continuum

      for - key insight - scientific theory - transition - from different - to similiar - key insight - organizing principle - organizes reality in new ways

      key insight - scientific theory - transition - from different - to similiar - New scientific theories make us cognitively reorganize our experiences - What was thought of as separate in an older conceptual framing - suddenly become similiar with the new framing

  3. Mar 2025
  4. Dec 2024
    1. there were a group of scientists that were trying to understand how the brain processes language, and they found something very interesting. They found that when you learn a language as a child, as a two-year-old, you learn it with a certain part of your brain, and when you learn a language as an adult -- for example, if I wanted to learn Japanese

      for - research study - language - children learning mother tongue use a different post off the brain then adults learning another language - from TED Talk - YouTube - A word game to convey any language - Ajit Narayanan

    1. current system is ‘closed source’, and is carried out by competitive agents that do not share innovations for very long time periods; the competitiveness of these agents requires behaviors that externalize costs

      for - examples - closed source IP externalises cost - from Substack article - The Cosmo-Local Plan for our Next Civilization - Michel Bauwens - 2024, Dec 20

      examples - closed source IP externalises cost - closed source circular economy is much more challenging than open source circular economy because - if inputs are kept secret and proprietary, reuse of End of life products are difficult to break down and reuse as input in a re-manufacturing process - closed IP creates fragmented and completing de facto standards that make interoperability impossible

    1. You describe how foundational stories of our Western, Christian paradigm are based on this idea of “a self-enclosed human realm separate from everything else,” and that this paradigm is a wound—one “so complete we can’t see it anymore, for it defines the very nature of what we assume ourselves to be.”

      for - human bubble, ailenated from nature, human world so different from natural world - nice meme - self-enclosed human realm separate from everything else - Emergence Magazine - interview - An Ethics of Wild Mind - David Hinton

  5. Sep 2024
  6. Apr 2024
  7. Jan 2024
  8. Jun 2023
  9. Sep 2022
  10. Apr 2022
  11. Feb 2022
  12. Sep 2021
  13. Apr 2021
  14. Mar 2021
  15. Feb 2021
  16. Oct 2020
    1. About the argument against it, "{@const will make code less consistent ": I think the same is true now, since people can come up with very different ways of dealing with the "computed value inside each loop/if function" problem. Some extract components, some use functions, some will prepare the array differently beforehand.
    2. it also allows for more divergence in how people write there code and where they put their logic, making different svelte codebases potentially even more different due to fewer constraints. This last point is actually something I really value, I read a lot of Svelte code by a lot of different people and broadly speaking things look the same and are in the same places.
  17. Sep 2020
  18. Jul 2020
  19. May 2020
  20. Apr 2020
  21. Mar 2020