11 Matching Annotations
  1. Sep 2023
  2. May 2023
    1. Minimum sample size for external validation of a clinicalprediction model with a binary outcome

      Minimum sample size for external validation of a clinical prediction model with a binary outcome

  3. Jul 2021
    1. case-driven trial was planned 205to accrue 130case

      What was the rationale for accrual of 130 cases has not been explained here. Would be nice to have that explanation. When the study parameters (95% confidence interval, 60% vaccine efficacy, 1% baseline attack rate) were applied to the WHO calculator obtained from here, the sample size turned out to be 86000, and when 80% confidence interval, 60% vaccine efficacy, and 1% baseline rate among unvaccinated) was used to assess sample size, it turned out to be 21000; in any case, the study then would be underpowered unless the rationale of 130 case accrual is made.<br> Why was not the WHO sample size estimator used?

  4. Mar 2021
  5. Feb 2021
  6. Jan 2021
  7. Nov 2020
    1. This is a page note. I can write overall comments about the pre-print here.

      Tags can also be added below.

  8. Oct 2020
  9. Aug 2020
  10. Jul 2020