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    Oncolytic Herpes Virus G47Δ Potentiates ADCC-Inducing Molecular Targeted Therapy via Coordinated Activation of Innate and Adaptive Immune Responses
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    A stand-alone ICln release module revealed by deconstructing the SMN complex with engineered Brr1
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    Targeting mitochondrial α-ketoglutarate sequestration disables dual oncogenic drivers and metabolic adaptability in pancreatic ductal adenocarcinoma
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    Genome-wide screening identifies ZFP91 as a key regulator of EVI1 in myeloid leukemia
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    Stepwise engagement of cingulate ensembles underlies motivational decline in chronic pain
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    Microglia-mediated extracellular matrix disruption drives neuronal dysfunction, motor impairments, and sedation following alcohol abuse
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    rAAV Fbxo7 gene therapy rescues the progressive nigrostriatal pathology in a mouse model of juvenile parkinsonism
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    Triazine Thiols Decrease Apolipoprotein B Secretion From Hepatocytes Through Inhibition of Human Carboxylesterase 1
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    PRAS40 enhances glycolysis by facilitating G6PI/PGK1/LDHA complex assembly in colorectal cancer
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    Identification of HSPE1 as a new actionable cancer vulnerability leads to an innovative and effective combination therapy for pancreatic ductal adenocarcinoma
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    Osmotin-derived 9-amino-acid peptide alleviates α-synuclein and MPTP-induced glial cell activation mediated neuroinflammation, protecting dopaminergic neurons in Parkinson’s disease mice brain
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    Gas vesicle-expressing human pluripotent stem cells enable multimodal ultrasound and optical coherence tomographic imaging
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    Deficiency of muscular dystrophy–related gene JAG2 causes NOTCH signaling dysfunction in muscle stem cells
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    In Vitro Inhibition of STAT5 Signaling Limits CD8+ T-cell Exhaustion and Improves Outcomes in Adoptive T-cell Therapy
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    Kozak sequence libraries for systematically characterizing transgenes across expression levels
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    DNA secondary structures in BCL2 and MYC elicit activation-induced cytidine deaminase binding and activity
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    EEPD1 evolved a unique DNA clamping dimer protecting reversed replication forks
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    Distal enhancers regulate mammalian early embryonic lineage differentiation through long-range interactions
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  41. Oct 2026
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    Computational design of optimized and preferentially paired human TCR constant regions for improved T cell function
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    Controlling the Subcellular Localization of Signaling Proteins Using Chemically Induced Dimerization and Optogenetics
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  47. Sep 2026
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    An antioxidant therapy elicits distinct transcriptome responses in 22q11-deleted upper layer cortical projection neurons
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    The senescence-inhibitory p53 isoform Δ133p53α represses the proinflammatory chemokine CXCL10 in progeria model mice and naturally aged mice
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    CDK12/13 inhibition overcomes platinum resistance by impairing RNA metabolism
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    Deubiquitination of NICD1 by USP10 Restrains Esophageal Cancer: A Link Between NOTCH1 Stabilization, Oxidative Stress, and Ferroptosis
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    Amanitin-Based Fc-Small Molecule–Drug Conjugates with Noncleavable Linker: A Novel Therapeutic Strategy for Prostate Cancer Targeted Therapy
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