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  1. May 2026
  2. 54.241.53.176 54.241.53.176
    KCCY_A_1780381_SM2861-html.html
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    Generation of the maternal iPSC line NCHi030-A from an unaffected heterozygous NOTCH1 variant carrier in a family with hypoplastic left heart syndrome
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    sciencedirect.com/science/article/pii/S1873506126001108
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    Generation of iPSC lines from myotonic dystrophy type 1 patients with varying CTG repeat lengths
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    sciencedirect.com/science/article/pii/S1873506126001091
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    Generation of hiPSCs (JUCGRMi008-A) from a β-propeller protein-associated neurodegeneration patient with WDR45 mutation
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    Generation of a human induced pluripotent stem cell line NTUHi007-A from a patient with Parkinson’s disease harboring a heterozygous missense mutation c.1858 G > A (p.D620N) in VPS35 gene
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    Non-competing Trop2 nanobody-based radiotheranostics for precision imaging and therapy of pancreatic cancer
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    sciencedirect.com/science/article/pii/S2590006426004746
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    Adapting in ovo RNAi as a tool to study gene function during neural circuit formation in the cerebellum
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    Reconstructing the west-east genetic division in Indonesia using ancient genomes
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    sciencedirect.com/science/article/pii/S2589004226013490
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    '-html.html
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    Aged circulating CD8+ T cells and their secreted factors drive cognitive decline
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    Deep molecular profiling of biliary tract cancer uncovers novel biological mechanisms and therapeutic opportunities
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    Vitamin D3 Prevents Epileptic Seizures by Modulating the Ras Signalling Pathway via Gnb1 and Casr in Acute Epilepsy Mouse Models
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    sciencedirect.com/science/article/pii/S0920121126000902
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    Reciprocal E-cadherin signaling aligns apical surfaces between neighboring epithelial tissues to complete the C. elegans digestive tract
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    Adipokine IL-11/IL-11Ra constrains sphingolipid metabolism to limit the thermogenic capacity of beige adipocytes
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    2026.05.07.723402v1.full-html.html
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    EFFECT OF Sb2Te3 SEMICONDUCTOR ON THE PHOTOVOLTAIC RESPONSE AND DEGRADATION OF CdTe/PEDOT: PSS HYBRID SOLAR CELLS
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    IFN-γ-induced AIM2-PANoptosis in granulosa cells leads to ovulatory dysfunction in polycystic ovary syndrome
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  19. link.springer.com link.springer.com
    An Intensity-Based Cropping Approach for Fast, Interpretable, and Robust Localization of the Knee Joint in Radiographs
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    link.springer.com/article/10.1007/s10278-026-01961-9
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    Molecular profiling of alpha-synuclein pathology and seeding activity in Parkinson’s disease
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    Broader gene representation by whole-exome sequencing improves accuracy of tumor mutational burden assessment for selection of pembrolizumab immunotherapy
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    link.springer.com/article/10.1007/s00262-026-04365-4
  22. 54.241.53.176 54.241.53.176
    2026.05.08.723765v1.full-html.html
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  23. www.biorxiv.org www.biorxiv.org
    Steppe Ancestry in western Eurasia and the spread of the Germanic Languages
    1
    1. JeanJP 15 May 2026

      I have a methodological concern about the qpAdm design used to model Iron Age France.

      If I understand the source construction correctly, the “local” Bronze Age proxy used for France is not a specifically French Bronze Age source, but a combined France/Iberia Bronze Age-related source. More importantly, the French Bronze Age individual included in this proxy appears to have an autosomal profile close to Basque/Iberian variation, and is paired with an Iberian genome. This makes the source a poor proxy for the broader local Bronze Age background of France, especially for northern, eastern or central French Iron Age targets.

      This matters because qpAdm results are highly sensitive to source choice. If the local Bronze Age proxy is shifted too far toward a Basque/Iberian-like profile, then Iron Age French individuals will mechanically require an additional Central European / Knovíz / Hallstatt-related source in order to fit. In that case, the inferred Central European contribution may partly reflect the inadequacy of the local proxy rather than a real demographic input from Hallstatt-associated populations.

      A stronger test would require modelling the French Iron Age targets against several alternative local Bronze Age sources: regional French Bronze Age proxies where available, eastern/northern/central French Bronze Age individuals separately, France Bronze Age without Iberian individuals, and only then Central European / Knovíz / Hallstatt-related sources in competition. It would also be useful to show whether the chosen France/Iberia Bronze Age source itself is representative of Bronze Age France, or whether it is an outlying southwestern/Basque-like proxy.

      As it stands, the model risks building the desired historical conclusion into the source design: a weak or unrepresentative “local” proxy can artificially create the need for a Central European Hallstatt-related component. This should be addressed before drawing strong conclusions about the demographic spread of Celtic languages into France.

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    biorxiv.org/content/10.1101/2024.03.13.584607v1
  24. en.wikipedia.org en.wikipedia.org
    Technology - Wikipedia
    3
    1. pennyxxx 15 May 2026
      After harnessing fire, humans discovered other forms of energy. The earliest known use of wind power is the sailing ship; the earliest record of a ship under sail is that of a Nile boat dating to around 7,000 BCE.[43] From prehistoric times, Egyptians likely used the power of the annual flooding of the Nile to irrigate their lands, gradually learning to regulate much of it through purposely built irrigation channels and "catch" basins.[44] The ancient Sumerians in Mesopotamia used a complex system of canals and levees to divert water from the Tigris and Euphrates rivers for irrigation.[45] Archaeologists estimate that the wheel was invented independently and concurrently in Mesopotamia (in present-day Iraq), the Northern Caucasus (Maykop culture), and Central Europe.[46] Time estimates range from 5,500 to 3,000 BCE with most experts putting it closer to 4,000 BCE.[47] The oldest artifacts with drawings depicting wheeled carts date from about 3,500 BCE.[48] More recently, the oldest-known wooden wheel in the world as of 2024 was found in the Ljubljana Marsh of Slovenia; Austrian experts have established that the wheel is between 5,100 and 5,350 years old.[49] The invention of the wheel revolutionized trade and war. It did not take long to discover that wheeled wagons could be used to carry heavy loads. The ancient Sumerians used a potter's wheel and may have invented it.[50] A stone pottery wheel found in the city-state of Ur dates to around 3,429 BCE,[51] and even older fragments of wheel-thrown pottery have been found in the same area.[51] Fast (rotary) potters' wheels enabled early mass production of pottery, but it was the use of the wheel as a transformer of energy (through water wheels, windmills, and even treadmills) that revolutionized the application of nonhuman power sources. The first two-wheeled carts were derived from travois[52] and were first used in Mesopotamia and Iran in around 3,000 BCE.[52] The oldest known constructed roadways are the stone-paved streets of the city-state of Ur, dating to c. 4,000 BCE,[53] and timber roads leading through the swamps of Glastonbury, England, dating to around the same period.[53] The first long-distance road, which came into use around 3,500 BCE,[53] spanned 2,400 km from the Persian Gulf to the Mediterranean Sea,[53] but was not paved and was only partially maintained.[53] In around 2,000 BCE, the Minoans on the Greek island of Crete built a 50 km road leading from the palace of Gortyn on the south side of the island, through the mountains, to the palace of Knossos on the north side of the island.[53] Unlike the earlier road, the Minoan road was completely paved.[53]Photograph of the Pont du Gard in France, one of the most famous ancient Roman aqueducts[54] Ancient Minoan private homes had running water.[55] A bathtub virtually identical to modern ones was unearthed at the Palace of Knossos.[55][56] Several Minoan private homes also had toilets, which could be flushed by pouring water down the drain.[55] The ancient Romans had many public flush toilets,[56] which emptied into an extensive sewage system.[56] The primary sewer in Rome was the Cloaca Maxima;[56] construction began on it in the sixth century BCE and it is still in use today.[56] The ancient Romans also had a complex system of aqueducts,[54] which were used to transport water across long distances.[54] The first Roman aqueduct was built in 312 BCE.[54] The eleventh and final ancient Roman aqueduct was built in 226 CE.[54] Put together, the Roman aqueducts extended over 450 km,[54] but less than 70 km of this was above ground and supported by arches.[54]

      large blocks of text may reduce readability and make it harder for some users to process information, especially for accessibility needs

    2. pennyxxx 15 May 2026
      cooking hypothesis.

      Hyperlinks are clearly marked and descriptive, which helps users understand where they will go before clicking, improving accessibility.

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    en.wikipedia.org/wiki/Technology
  25. tw-preview.dev.amust.local tw-preview.dev.amust.local
    Licensing - User Guide
    1
    1. martynh 15 May 2026
      Veeam offers annual and multi-year subscriptions that include 1 TB of storage capacity. Any storage use over this capacity is subject to monthly charges.

      As far as I understand this is only accurate for Azure/AWS marketplace. Traditional contracts might include any amount of storage (in 1tb blocks)

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    tw-preview.dev.amust.local/html/vdc/draft/main-vdc-lm-vaultlicense/userguide/vault_licensing.html
  26. en.wikipedia.org en.wikipedia.org
    Wikipedia, the free encyclopedia
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