Zhang, L., Jackson, C. B., Mou, H., Ojha, A., Rangarajan, E. S., Izard, T., Farzan, M., & Choe, H. (2020). The D614G mutation in the SARS-CoV-2 spike protein reduces S1 shedding and increases infectivity. BioRxiv, 2020.06.12.148726. https://doi.org/10.1101/2020.06.12.148726
- Jul 2020
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-
Sapoval, N., Mahmoud, M., Jochum, M. D., Liu, Y., Elworth, R. A. L., Wang, Q., Albin, D., Ogilvie, H., Lee, M. D., Villapol, S., Hernandez, K., Berry, I. M., Foox, J., Beheshti, A., Ternus, K., Aagaard, K. M., Posada, D., Mason, C., Sedlazeck, F. J., & Treangen, T. J. (2020). Hidden genomic diversity of SARS-CoV-2: Implications for qRT-PCR diagnostics and transmission. BioRxiv, 2020.07.02.184481. https://doi.org/10.1101/2020.07.02.184481
-
- Jun 2020
-
www.biorxiv.org www.biorxiv.org
-
Starr, T. N., Greaney, A. J., Hilton, S. K., Crawford, K. H., Navarro, M. J., Bowen, J. E., Tortorici, M. A., Walls, A. C., Veesler, D., & Bloom, J. D. (2020). Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding [Preprint]. Microbiology. https://doi.org/10.1101/2020.06.17.157982
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-
twitter.com twitter.com
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Bloom Lab. (2020, June 18). "We've experimentally measured how all amino-acid mutations to the #SARSCoV2 spike RBD affect ACE2 binding and expression of folded protein in a deep mutational scanning study led by @tylernstarr & Allie Greaney:https://biorxiv.org/content/10.1101/2020.06.17.157982v1 Why is this important? (1/n)" Twitter. https://twitter.com/jbloom_lab/status/1273468539484213248
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threader.app threader.app
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Balloux, F. (2020, May 22) A thread written by @BallouxFrancois. Threader. https://threader.app/thread/1263745877702737920
-
- May 2020
-
www.nature.com www.nature.com
-
Andersen, K.G., Rambaut, A., Lipkin, W.I. et al. The proximal origin of SARS-CoV-2. Nat Med 26, 450–452 (2020). https://doi.org/10.1038/s41591-020-0820-9
-
-
www.scientificamerican.com www.scientificamerican.com
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Krzywinski, M. F., Martin. (n.d.). Virus Mutations Reveal How COVID-19 Really Spread. Scientific American. Retrieved May 6, 2020, from https://www.scientificamerican.com/article/virus-mutations-reveal-how-covid-19-really-spread1/
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- May 2018
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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SRSF1-Regulated Alternative Splicing in Breast Cancer
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www.cell.com www.cell.com
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Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types
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- Nov 2017
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gmt.genome.wustl.edu gmt.genome.wustl.edu
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SomaticSniper
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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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tier 1 contains all changes in the amino acid coding regions of annotated exons, consensus splice-site regions, and RNA genes (including microRNA genes). Tier 2 contains changes in highly conserved regions of the genome or regions that have regulatory potential. Tier 3 contains mutations in the nonrepetitive part of the genome that does not meet tier 2 criteria, and tier 4 contains mutations in the remainder of the genome
Tags
Annotators
URL
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onlinelibrary.wiley.com onlinelibrary.wiley.com
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The background puzzle: how identical mutations in the same gene lead to different disease symptoms
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- Sep 2017
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www.nature.com www.nature.com
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Parental influence on human germline de novo mutations in 1,548 trios from Iceland
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