38 Matching Annotations
  1. Sep 2025
    1. that in the offspring even of thoroughly pure-bred stocks, avery small number of individuals, say two or three in tens ofthousands, turn up with small but 'jump-like' changes, theexpression 'jump-like' not meaning that the change is so veryconsiderable, but that there is a discontinuity inasmuch asthere are no intermediate forms between the unchanged andthe few changed. De Vries called that a mutation.

      But about forty years ago the Dutchman de Vries discovered

      https://en.wikipedia.org/wiki/Hugo_de_Vries

    2. In calling the structure of the chromosome fibres a code-script

      from where does he draw the idea "code-script"? Is it from the developing information theory of the time? Somewhere else?

      There is definitely the idea of a code running in the sense of programming, which was likely not a common conceptualization at the time.


      On p. 22 he uses the phrase "law-code" which is likely the closer meaning of code he's using and not the sense of genetic code as understood much later when DNA and the underlying protein coding sequences were unraveled.

      Morse code may also be a tangential underlying meaning of his sense of "code" as something unknown but potentially revealable.

    3. The reason for this is, that what we call thought (I) is itselfan orderly thing, and (2) can only be applied to material, i.e.to perceptions or experiences, which have a certain degree oforderliness.

      Jeremy.Olsen — 9/16/25, 8:21 AM Opening question for 9/16 - Regarding Schrödinger's description of thought on p.9 (Canto Classics edition):

      "...what we call thought (1) is itself an orderly thing, and (2) can only be applied to material, i.e. to perceptions or experiences, which have a certain degree of orderliness."

      My question is as follows: What exactly is the material of thought for Schrödinger, which he calls "perceptions or experiences"? What are examples of this material for him? What is excluded from this category?

    4. Some time ago we were told in thenewspapers that in his African campaign General Mont-gomery made a point of having every single soldier of his armymeticulously informed of all his designs. If that is true (as itconceivably might be, considering the high intelligence andreliability of his troops) it provides an excellent analogy to ourcase, in which the corresponding fact certainly is literally true.

      You have to love the analogy of General Montgomery to chromosomes here and the duplication of information.

      Everyone knows the general direction they're moving, though the information in soldiers is different in form and function versus chromosomes which aren't conscious.

      What happens when a soldier is captured and questioned though? How does that effect strategy and does it outweigh the effects of a commander dying and their next in command being able to quickly take over? or of the individual soldier presented by a difficulty, but able to make a decision because they know where the general might direct them for the outcome the general desired?

    5. I must begin with giving a brief summary of the situation inbiology, more especially in genetics - in other words, I haveto summarize the present state of knowledge in a subject ofwhich I am not a master. This cannot be helped and Iapologize, particularly to any biologist, for the dilettantecharacter of my summary.

      While an apology to professionals, it also stands as an apology to the reasonably well-educated and non specialist decades later as well.

    6. You have to multiplyobservations, in order to eliminate the effect of the Brownianmovement of your instrument. This example is, I think,particularly illuminating in our present investigation. For ourorgans of sense, after all, are a kind of instrument. We can seehow useless they would be if they became too sensi tive.
    7. Why shouldan organ like our brain, with the sensorial system attached toit, of necessity consist of an enormous number of atoms, inorder that its physically changing state should be in close andintimate correspondence with a highly developed thought?
    8. Even if I should be right in this, I do not know whether myway of approach is really the best and simplest. But, in short,it was mine. The 'naive physicist' was myself. And I could notfind any better or clearer way towards the goal than my owncrooked one.

      an attempt is better than nothing at all

      "If at first you don't suck seed, keep on sucking until you do succeed." - Curly of the Three Stooges while eating a peach

    9. The large and important and very much discussed question is:How can the events in space and time which take place withinthe spatial boundary of a living organism be accounted for byphysics and chemistry?

      the question on which he'll be focusing the book

      Come back when we're done to see how well he may have answered it.

    10. DelbruckJs Model Discussed and Tested

      n.b. Delbrück was Jim Watson’s postdoc advisor at Caltech

      see also:<br /> Golomb, Solomon W. Construction and Properties of Comma-Free Codes. With L. R. Welch and Max Delbrück, København, 1958. Biologiske Meddelelser Udg. Af Det Kongelige Danske Videnskabernes Selskab 23.

      Golomb, S. W., et al. “Comma-Free Codes.” Canadian Journal of Mathematics, vol. 10, Jan. 1958, pp. 202–09. Cambridge University Press, https://doi.org/10.4153/CJM-1958-023-9.

    11. Reading list: https://docs.google.com/spreadsheets/d/1lCufgJO4WJJpO6EUpGggeWdz9UnAahGbwDL_IEKfYAU/edit?gid=0#gid=0

      Date Section <br /> 9/16/25 What is Life? Preface, Chapter 1<br /> 9/23 Chapter 2<br /> 9/30 Chapter 3<br /> 10/7 Chapter 4<br /> 10/14 Chapter 5<br /> 10/21 Chapter 6<br /> 10/28 Chapter 7<br /> 11/4 Epilogue<br /> 11/11 Mind and Matter Chapter 1<br /> 11/18 Chapter 2<br /> 11/25 BREAK<br /> 12/2 Chapter 3 + 4<br /> 12/9 Chapter 5<br /> 12/16 Chapter 6

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