Since we are no longer inclined to eliminatefailures in the harsh way the Lacedemonians used to adopt inthe Taygetos mountain,
Is he pro or anti-eugenics here? esp. with respect to his time?
Since we are no longer inclined to eliminatefailures in the harsh way the Lacedemonians used to adopt inthe Taygetos mountain,
Is he pro or anti-eugenics here? esp. with respect to his time?
In using the picture we usually forgetabout them, except in the quite general way that we know ouridea of a light-wave is not a haphazard invention of a crankbut is based on experiment.
His paper was forgotten and was onlyrediscovered in 1900, simultaneously and independently, byCorrens (Berlin), de Vries (Amsterdam) and Tschermak(Vienna).
The results he published as early as1866 in the Proceedings of the Naturforschender Verein in Brunn.
A recessive allele influences the phenotype only when thegenotype is homozygous.
that mutations are very oftenlatent
de Vries first published his discovery, in 1902
de Vries, Hugo. Die Mutationstheorie. Versuche und Beobachtungen über die Entstehung von Arten im Pflanzenreich, Leipzig, Veit & Comp., 1901-03.
In other words, he would have expected to produce byselection an increase of the average length of the awns.
compare with Galton:<br /> Galton, F. (1886). "Regression towards mediocrity in hereditary stature". The Journal of the Anthropological Institute of Great Britain and Ireland. 15: 246–263. doi:10.2307/2841583. JSTOR 2841583.
that in the offspring even of thoroughly pure-bred stocks, avery small number of individuals, say two or three in tens ofthousands, turn up with small but 'jump-like' changes, theexpression 'jump-like' not meaning that the change is so veryconsiderable, but that there is a discontinuity inasmuch asthere are no intermediate forms between the unchanged andthe few changed. De Vries called that a mutation.
But about forty years ago the Dutchman de Vries discovered
In calling the structure of the chromosome fibres a code-script
from where does he draw the idea "code-script"? Is it from the developing information theory of the time? Somewhere else?
There is definitely the idea of a code running in the sense of programming, which was likely not a common conceptualization at the time.
On p. 22 he uses the phrase "law-code" which is likely the closer meaning of code he's using and not the sense of genetic code as understood much later when DNA and the underlying protein coding sequences were unraveled.
Morse code may also be a tangential underlying meaning of his sense of "code" as something unknown but potentially revealable.
The reason for this is, that what we call thought (I) is itselfan orderly thing, and (2) can only be applied to material, i.e.to perceptions or experiences, which have a certain degree oforderliness.
Jeremy.Olsen — 9/16/25, 8:21 AM Opening question for 9/16 - Regarding Schrödinger's description of thought on p.9 (Canto Classics edition):
"...what we call thought (1) is itself an orderly thing, and (2) can only be applied to material, i.e. to perceptions or experiences, which have a certain degree of orderliness."
My question is as follows: What exactly is the material of thought for Schrödinger, which he calls "perceptions or experiences"? What are examples of this material for him? What is excluded from this category?
Whatdegree of permanence do we encounter in hereditaryproperties and what must we therefore attribute to thematerial structures which carry them?
The course of events is appropriately called alternation ofgenerations.
syngamy
the fusion of two cells, or of their nuclei, in reproduction.
essentially similar to fertilization
Some time ago we were told in thenewspapers that in his African campaign General Mont-gomery made a point of having every single soldier of his armymeticulously informed of all his designs. If that is true (as itconceivably might be, considering the high intelligence andreliability of his troops) it provides an excellent analogy to ourcase, in which the corresponding fact certainly is literally true.
You have to love the analogy of General Montgomery to chromosomes here and the duplication of information.
Everyone knows the general direction they're moving, though the information in soldiers is different in form and function versus chromosomes which aren't conscious.
What happens when a soldier is captured and questioned though? How does that effect strategy and does it outweigh the effects of a commander dying and their next in command being able to quickly take over? or of the individual soldier presented by a difficulty, but able to make a decision because they know where the general might direct them for the outcome the general desired?
Ontogenesis is the development of the individual, during its lifetime, as opposed tophylogenesis, the development of species within geological periods.
How might we apply ontogeny vs. phylogeny in the political sphere within @Lanier2013s framing Who Owns the Future or in the personbyte/firmbyte framing of @Hidalgo2015?
four-dimensional pattern
What a great conceptualization of considering organisms in time and space... something we don't do now as well as we ought to almost 80+ years later
One might presume as a physicist he's taking advantage of Einstein's conceptualization of spacetime, but here within biology.
I must begin with giving a brief summary of the situation inbiology, more especially in genetics - in other words, I haveto summarize the present state of knowledge in a subject ofwhich I am not a master. This cannot be helped and Iapologize, particularly to any biologist, for the dilettantecharacter of my summary.
While an apology to professionals, it also stands as an apology to the reasonably well-educated and non specialist decades later as well.
Das Sein ist ewig; denn GesetzeBewahren die lebend'gen Schatze,Aus welchen sich das All geschmiickt. I GOETHE
Translation:
Being is eternal; for there are laws to conserve the treasures of life on which the Universe draws for beauty.
This reminds me of the equivalence relational quote by Eddington
The laws of physics and physical chemistry areinaccurate within a probable relative error of the order of I Ivn,where n is the number of molecules that co-operate to bringabout that law - to produce its validity within such regions ofspace or time (or both) that matter, for some considerations orfor some particular experiment.
Y n law
square root of n law
You have to multiplyobservations, in order to eliminate the effect of the Brownianmovement of your instrument. This example is, I think,particularly illuminating in our present investigation. For ourorgans of sense, after all, are a kind of instrument. We can seehow useless they would be if they became too sensi tive.
Curie'slaw
This ingenious explanation is due to the French physicist P.Langevin.
And why could all this not be fulfilled in the case of anorganism composed of a moderate number of atoms only andsensitive already to the impact of one or a few atoms only?
Is he getting at the idea of consciousness? An organism must have a "large enough" machinery to be considered conscious at some level? How many physical moving parts and what links between them?
Why shouldan organ like our brain, with the sensorial system attached toit, of necessity consist of an enormous number of atoms, inorder that its physically changing state should be in close andintimate correspondence with a highly developed thought?
Even if I should be right in this, I do not know whether myway of approach is really the best and simplest. But, in short,it was mine. The 'naive physicist' was myself. And I could notfind any better or clearer way towards the goal than my owncrooked one.
an attempt is better than nothing at all
"If at first you don't suck seed, keep on sucking until you do succeed." - Curly of the Three Stooges while eating a peach
compare his theoretical anticipations with the biological facts.
here he's outlining the idea of scientific method
the most essential part of a living cell - the chromosome fibre- may suitably be called an aperiodic crystal.
compare this with crystalized information as expounded in: Hidalgo, César A. Why Information Grows: The Evolution of Order, from Atoms to Economies. Basic Books, 2015, https://www.basicbooks.com/titles/cesar-hidalgo/why-information-grows/9780465048991/.
The large and important and very much discussed question is:How can the events in space and time which take place withinthe spatial boundary of a living organism be accounted for byphysics and chemistry?
the question on which he'll be focusing the book
Come back when we're done to see how well he may have answered it.
The reason for this wasnot that the subject was simple enough to be explainedwithout mathematics, but rather that it was much tooinvolved to be fully accessible to mathematics.
It wouldn't be until almost a decade later that Delbruck, Golomb, et al. would be using math on the topic.
the lectures could not be termed popular, eventhough the physicist's most dreaded weapon, mathematicaldeduction, would hardly be utilized.
was this possibly the inspiration of Cathy O'Neill's book title?
some of us should venture toembark on a synthesis of facts and theories, albeit withsecond-hand and incomplete knowledge of some of them -and at the risk of making fools of ourselves.
W e have inherited from our forefathers the keen longing forunified, all-embracing knowledge.
Schrödinger, Erwin. What Is Life? With Mind and Matter and Autobiographical Sketches. Cambridge University Press, 1992.
Originally published in 1944 based on lectures delivered under the auspices of the Dublin Institute for Advanced Studies at Trinity College, Dublin, in February 1943
Annotation URL: urn:x-pdf:4450b6f08de5b847d68ddef3bbe5ba47
THE RELATION BETWEEN CLOCKWORK ANDORGANISM
historical evidence of the scientific shift from Newtonian clockwork physics into an underlying statical mechanical one
DelbruckJs Model Discussed and Tested
n.b. Delbrück was Jim Watson’s postdoc advisor at Caltech
see also:<br /> Golomb, Solomon W. Construction and Properties of Comma-Free Codes. With L. R. Welch and Max Delbrück, København, 1958. Biologiske Meddelelser Udg. Af Det Kongelige Danske Videnskabernes Selskab 23.
Golomb, S. W., et al. “Comma-Free Codes.” Canadian Journal of Mathematics, vol. 10, Jan. 1958, pp. 202–09. Cambridge University Press, https://doi.org/10.4153/CJM-1958-023-9.
Reading list: https://docs.google.com/spreadsheets/d/1lCufgJO4WJJpO6EUpGggeWdz9UnAahGbwDL_IEKfYAU/edit?gid=0#gid=0
Date Section <br /> 9/16/25 What is Life? Preface, Chapter 1<br /> 9/23 Chapter 2<br /> 9/30 Chapter 3<br /> 10/7 Chapter 4<br /> 10/14 Chapter 5<br /> 10/21 Chapter 6<br /> 10/28 Chapter 7<br /> 11/4 Epilogue<br /> 11/11 Mind and Matter Chapter 1<br /> 11/18 Chapter 2<br /> 11/25 BREAK<br /> 12/2 Chapter 3 + 4<br /> 12/9 Chapter 5<br /> 12/16 Chapter 6