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  1. Last 7 days
    1. the question is why are the mitochondria not doing their job why is the self not responding to insulin 00:05:34 that's the issue different tissues different reasons but the main one is the liver

      for - question - health - insulin resistance - why aren't mitochondria within cells not responding to insulin?

      question - health - insulin resistance - why aren't mitochondria within cells not responding to insulin? - The fat cells are being stored in the liver, resulting in - fatty liver disease - The liver stores the fat cells floating in blood (triglycerides) then recirculates it back to the cells. - The cells and liver are caught up in a vicious cycle of "hot potatos" with the fat cells.<br /> - (See Stanford explainer video above)

  2. Jun 2024
  3. Feb 2024
  4. Jan 2024
    1. Instance methods Instances of Models are documents. Documents have many of their own built-in instance methods. We may also define our own custom document instance methods. // define a schema const animalSchema = new Schema({ name: String, type: String }, { // Assign a function to the "methods" object of our animalSchema through schema options. // By following this approach, there is no need to create a separate TS type to define the type of the instance functions. methods: { findSimilarTypes(cb) { return mongoose.model('Animal').find({ type: this.type }, cb); } } }); // Or, assign a function to the "methods" object of our animalSchema animalSchema.methods.findSimilarTypes = function(cb) { return mongoose.model('Animal').find({ type: this.type }, cb); }; Now all of our animal instances have a findSimilarTypes method available to them. const Animal = mongoose.model('Animal', animalSchema); const dog = new Animal({ type: 'dog' }); dog.findSimilarTypes((err, dogs) => { console.log(dogs); // woof }); Overwriting a default mongoose document method may lead to unpredictable results. See this for more details. The example above uses the Schema.methods object directly to save an instance method. You can also use the Schema.method() helper as described here. Do not declare methods using ES6 arrow functions (=>). Arrow functions explicitly prevent binding this, so your method will not have access to the document and the above examples will not work.

      Certainly! Let's break down the provided code snippets:

      1. What is it and why is it used?

      In Mongoose, a schema is a blueprint for defining the structure of documents within a collection. When you define a schema, you can also attach methods to it. These methods become instance methods, meaning they are available on the individual documents (instances) created from that schema.

      Instance methods are useful for encapsulating functionality related to a specific document or model instance. They allow you to define custom behavior that can be executed on a specific document. In the given example, the findSimilarTypes method is added to instances of the Animal model, making it easy to find other animals of the same type.

      2. Syntax:

      Using methods object directly in the schema options:

      javascript const animalSchema = new Schema( { name: String, type: String }, { methods: { findSimilarTypes(cb) { return mongoose.model('Animal').find({ type: this.type }, cb); } } } );

      Using methods object directly in the schema:

      javascript animalSchema.methods.findSimilarTypes = function(cb) { return mongoose.model('Animal').find({ type: this.type }, cb); };

      Using Schema.method() helper:

      javascript animalSchema.method('findSimilarTypes', function(cb) { return mongoose.model('Animal').find({ type: this.type }, cb); });

      3. Explanation in Simple Words with Examples:

      Why it's Used:

      Imagine you have a collection of animals in your database, and you want to find other animals of the same type. Instead of writing the same logic repeatedly, you can define a method that can be called on each animal instance to find similar types. This helps in keeping your code DRY (Don't Repeat Yourself) and makes it easier to maintain.

      Example:

      ```javascript const mongoose = require('mongoose'); const { Schema } = mongoose;

      // Define a schema with a custom instance method const animalSchema = new Schema({ name: String, type: String });

      // Add a custom instance method to find similar types animalSchema.methods.findSimilarTypes = function(cb) { return mongoose.model('Animal').find({ type: this.type }, cb); };

      // Create the Animal model using the schema const Animal = mongoose.model('Animal', animalSchema);

      // Create an instance of Animal const dog = new Animal({ type: 'dog', name: 'Buddy' });

      // Use the custom method to find similar types dog.findSimilarTypes((err, similarAnimals) => { console.log(similarAnimals); }); ```

      In this example, findSimilarTypes is a custom instance method added to the Animal schema. When you create an instance of the Animal model (e.g., a dog), you can then call findSimilarTypes on that instance to find other animals with the same type. The method uses the this.type property, which refers to the type of the current animal instance. This allows you to easily reuse the logic for finding similar types across different instances of the Animal model.

      Certainly! Let's go through each part and explain it in simple terms: ### 1. `this` in Mongoose: - **What is `this`?** In JavaScript, `this` refers to the current context or object. In Mongoose, particularly within methods and middleware functions, `this` represents the instance (document) the function is currently operating on. - **Why is it used?** `this` is used to access and modify the properties of the current document. For example, in a Mongoose method, `this` allows you to refer to the fields of the specific document the method is called on. ### 2. Example: Let's use the `userSchema.pre("save", ...)`, which is a Mongoose middleware, as an example: ```javascript userSchema.pre("save", async function (next) { if (!this.isModified("password")) { next(); } else { this.password = await bcrypt.hash(this.password, 10); next(); } }); ``` - **Explanation in Simple Words:** - Imagine you have a system where users can sign up and set their password. - Before saving a new user to the database, you want to ensure that the password is securely encrypted (hashed) using a library like `bcrypt`. - The `userSchema.pre("save", ...)` is a special function that runs automatically before saving a user to the database. - In this function: - `this.isModified("password")`: Checks if the password field of the current user has been changed. - If the password is not modified, it means the user is not updating their password, so it just moves on to the next operation (saving the user). - If the password is modified, it means a new password is set or the existing one is changed. In this case, it uses `bcrypt.hash` to encrypt (hash) the password before saving it to the database. - The use of `this` here is crucial because it allows you to refer to the specific user document that's being saved. It ensures that the correct password is hashed for the current user being processed. In summary, `this` in Mongoose is a way to refer to the current document or instance, and it's commonly used to access and modify the properties of that document, especially in middleware functions like the one demonstrated here for password encryption before saving to the database.

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  5. Dec 2023
    1. Kickstarter will not let me promise rewards within the same month, but the files will be sent to backers soon after the campaign ends.
  6. Nov 2023
  7. Mar 2023
  8. Jan 2023
    1. Do not separate numbers from letters on symbols, methods and variables.

      Okay... Why not?

  9. Dec 2022
    1. If a contact ever reaches out and is no longer receiving messages because they accidentally marked one of your campaigns as spam, you can reach out to Product Support. We can remove them from the suppression list for you. 

      why not allow user to do it directly instead of force to contact support? If they'll remove it for you because you said the user asked you to... why not just let you remove the suppression yourself? Mailgun lets you directly delete suppressions via their API.

  10. Oct 2022
  11. Sep 2022
  12. Aug 2022
    1. The task is not deleted, but the two are no longer connected. It’s not possible to connect them again.

      Should be possible!

  13. Jul 2022
  14. May 2022
    1. "I didn't fully understand it at the time, but throughout my time as a freshman at Boston College I've realized that I have the power to alter myself for the better and broaden my perspective on life. For most of my high school experience, I was holding to antiquated thoughts that had an impact on the majority of my daily interactions. Throughout my life, growing up as a single child has affected the way am in social interactions. This was evident in high school class discussions, as I did not yet have the confidence to be talkative and participate even up until the spring term of my senior year."

    2. "The need to engage with people in terms of evaluating them for the aim of acquiring a different point of view was one occasion this semester where the knowledge I received in class positively changed the way I approached an issue. I was patient enough to explore other perspectives, some of which disagreed with mine, so that I might learn about their opinions without bias or prejudice."

  15. Nov 2021
  16. Sep 2021
  17. Jul 2021
    1. Please note that the strategy: :build option must be passed to an explicit call to association, and cannot be used with implicit associations:
  18. Jun 2021
    1. Do not use aria-orientation attribute for standard list (i.e., role="list"), use component's vertical property to set the orientation to vertical.
  19. May 2021
    1. Note that not all of the colors in SMUI read from CSS variables, so some parts will still use the colors defined in the original Sass compile.
  20. Apr 2021
    1. Already Signed InThis session has ended because the account has been signed into from another browser window on 04/11/2021 04:30:09 PM. This happens when you sign in to your account on more than one browser screen. You can't be signed into your account on two or more browser windows at the same time. Just close your browser and sign back into your account.
  21. Mar 2021
    1. Dole Mandarin Oranges in Light Syrup, All Natural Fruit, Non-GMO, 15oz CanNot available for curbside
  22. Feb 2021
  23. Jan 2021
    1. The Gmail Android app that comes pre-installed with most new Android phones contains a feature to access non-Google accounts using POP and IMAP. Unfortunately, emails accessed through this setup lack the embedded style (<style>) support as well as the support for background images.
    1. On Ubuntu, Chromium is not the default browser, and the package resides in the ‘universe’ section of the archive.
  24. Dec 2020
  25. Nov 2020
  26. Oct 2020
  27. Sep 2020
    1. You must: reference each element you are extending using refs or an id add code in your oncreate and ondestroy for each element you are extending, which could become quite a lot if you have a lot of elements needing extension (anchors, form inputs, etc.)
    2. This is where hooks/behaviors are a good idea. They clean up your component code a lot. Also, it helps a ton since you don't get create/destroy events for elements that are inside {{#if}} and {{#each}}. That could become very burdensome to try and add/remove functionality with elements as they are added/removed within a component.
  28. Jun 2019
    1. AtthecoreofmyargumentisthewayinwhichGooglebiasessearchtoitsowneconomicinterests—foritsprofitabilityandtobolsteritsmarketdominanceatanyexpense

      I have been trying to avoid the word "money" in my annotations to avoid coming off as anti-capitalist as I really am, but yes: Corporations do not give a care about individuals or marginalized groups outside of how they can profit off of their oppression. Remember this June; this Pride Month; that any company selling you rainbow merchandise is not doing it out of legitimate care about LGBTQ+ rights but because it's profitable! Yes, even if they're giving 20% of proceeds to charity - where do you think the other 80% goes?