- Last 7 days
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elifesciences.org elifesciences.org
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DOI https://doi.org/10.35077/g.933.
DOI: 10.7554/eLife.85521
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- Jul 2024
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elifesciences.org elifesciences.org
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Yet, some RNA strands can also fold to form ribozymes, 3D structures that could have guided life’s chemical processes the way proteins do now.
Ribosomes are made up of rRNA and proteins. I was unaware of this until this reading
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Taken together, the interaction of triplet substrate pools with RNA templates promotes uncoupling of an RNA’s sequence (i.e. information content, and associated folding tendencies) from its replicability, thereby enhancing RNA’s capacity to serve as an informational polymer.
i wonder what the effects of this would look like on a person compared to someone without triplet substrate pools
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For instance, when binding templates, triplets incur a lower entropic cost per position compared to canonical mononucleotides (thus aiding copying of sequences rich in weakly pairing A and U bases),
Dose this imply that cellular functioning such as the repairing damaged skin could effectively be done quicker with triplet substrates?
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When RNA is copied, one strand acts as a template, and a replicase ribozyme would accurately guide which letters are added to the strand under construction.
Similar to a chef making a recipe and someone at home following that recipe
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iterative RNA-templated oligonucleotide ligation
I was a bit confused by this term and found that it means synthesis of longer RNA sequences from shorter oligonucleotides which is guided by an RNA templet.
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reciprocally synthesizing their own ‘+’ and ‘–’ strands
From Biology LibreText: Positive-sense viral RNA is similar to mRNA and thus can be immediately translated by the host cell. Negative-sense viral RNA is complementary to mRNA and thus must be converted to positive-sense RNA by an RNA polymerase before translation.
For some context about the information.
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wondered if choosing different building blocks might overcome this contradiction.
What does he mean by building blocks, is it DNA vs RNA?
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molecule must have had the ability to make copies of itself.
RNA folding is a common process when RNA is synthesized. After researching the process is called cotranscriptional folding and is thought to impact gene expression and RNA function.
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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AB_2722471
DOI: 10.7554/eLife.98020
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How can sex comb melanization affect sex comb function? In insects, melanization impacts not only the color of the adult cuticle but also its mechanical stiffness
Key point of why only 3% of y1 male fruit flies are able to mate.
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yellow on male
Just wanted to throw out that it may be important to study males due to the yellow gene being a sex-linked trait. Males will have a greater chance of inheriting the phenotype as they only require one X chromosome to display it.
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The interaction between Yellow and dopamine might explain the protein’s effects on male mating success because dopamine acts as a modulator of male courtship drive in D. melanogaster (Zhang et al., 2016).
Dose this mean a fly in a lab setting could mate less than a true wild fruit fly? (assuming lab flies produce less dopamine compared to their wild counterpart)
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which was perceived as a behavioral defect for decades, is caused by changes in the morphology of the structures used during mating. Other recent studies have also shown the importance of morphological structures for stickleback schooling (Greenwood et al., 2015), water strider walking (Santos et al., 2017), and cricket singing (Pascoal et al., 2014) behaviors.
Using this knowledge, I wonder if eye color could also effect the chances of mating in these fruit flies.
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Video recordings of male flies with reduced yellow expression in dsx-expressing cells showed the same mating defect observed in y1 mutants: males seem to perform all courtship actions normally, but repeatedly failed to copulate (Video 5).
This leads me to question if females mate more to visual cues rather than chemical cues.
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- Jun 2024
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elifesciences.org elifesciences.org
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For example, D. pachea is endemic to the Sonoran Desert of North America, where it depends on the sterols in the cactus Lophocereus schottii, which has alkaloids that other Drosophila species cannot tolerate. Because of its obligate association with its cactus host, it is exposed to temperatures that often approach 50°C. Such species provide unprecedented opportunities to understand the genetic bases of adaptations to extreme situations (see Box 1) and to recruit these species to address problems of species loss in the face of global warming and other anthropogenic changes.
Interesting, kind of similar to how different species of mammals adapt to different environments and even take on adaptations necessary to survive in that environment. I think that studying evolutionary adaptations of these drosophila could help to combat species loss as it would give us insight towards generational survival.
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D. melanogaster, described by Meigen in 1830, appears to have originated in sub-Saharan Africa (Lachaise et al., 1988). The first out-of-Africa habitat expansion of D. melanogaster is thought to have occurred between 10,000 and 15,000 years ago, when it moved to Europe and Asia
Throughout my undergrad research, I have found that most species whos evolutionary history or point of origin is tracked usually comes out of africa and then moves into europe or north america. This the same for humans, and felids to my knowledge. However, Canids seem to have originated in Northeast Asia.
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The genetic bases of these specializations, as they relate to phenomena such as the evolution of pesticide resistance (
Does this mean pesticides are a human made product that impact insects in the same capacity as allelochmeicals and secondary metabolites?
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human disease
I didn't see any evidence pointing to the commonalities between human genes and fruit fly gene sequence, is this part of the reasoning why the species can be used for this purpose?
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ales appear to sort themselves out by size at the mating site, with smaller males often being found in parts of the fruit where there are fewer females and thus fewer matings
This is extremely interesting. I wonder what this means for the future of the species as it seems a greater concentration of larger males are mating with females. Are the mother's genetics what keep a variety of sizes present within a population?
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In the laboratory, life is simple.
I wonder is this attributes to domestication of fruit flies even if this is not a term used in relation to the species.
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oviposition
I am a bit confused by this. Does the placement of eggs impact natural selections placed upon D. melanogaster?
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ecological generalist
This is extremely important to cultivating D. melanogaster in a lab environment and points to the species adaptability to thrive in a variety of conditions.
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Another product of anthropogenic change is the evolution of pesticide resistance in a wide range of insects of economic and medical importance.
can this be used to reflect people's natural resistance to certain diseases?
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What role can natural history play in our ability to understand these interactions with a view towards disease mitigation and treatment? In the past few decades, the importance of the gut microbiome for models of human health has grown.
kinda surprising that they could use something as small as these flies to study gut microbes, I wonder what type of tools they use to study this.
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It is not clear why or how he came to breed them, but their short generation time and ease of rearing were probably very appealing attributes.
When it comes to model organisms, a short generation time is essential that way we can quickly see the results of potential crosses, another model organism that has a short generation time is the zebrafish
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elifesciences.org elifesciences.org
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ematostella vectensis suggests that venom is already expressed in eggs and larvae of this species.
an example that this venom was not originally in the animal but was developed over a long period of time
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NvePTx1 is indeed a toxin
Is there any way to test if they are neurotoxins, cytotoxins, or hemotoxins?
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by ectodermal gland cells
This relates to gbonet's comment on spiders and the Cnidaria's evolutionary similarities. In an article I read, it pointed out that the epithelia of three major salivary glands may be of ectodermal origin, and spiders deliver venom from modified salivary glands.
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A planula larva emerges from the egg package 48–72 hpf and starts swimming in the water
I am a bit excited that I predicted this information after researching a bit of the first few sentences!
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They then become swimming larvae, barely visible to the naked eye, that do not feed
This interested me and I was wondering if these would be considered planula larvae? If so it is extremely interesting and I wonder when their mouth and digestive tract develop. I also learned a new term-- lecithotrophy. Which means that they feed on egg yolk and materials put in the egg by the mother (I would assume the ladder is not applicable since the sea anemones shoot out their sperm and eggs to reproduce there is not time for preparation of greater material).
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The oldest extant group of venomous animals is the marine phylum Cnidaria, which includes sea anemones, corals, jellyfish and hydroids.
I wonder when comparing the evolutionary tree of a Cnidaria species to the evolutionary tree of a snake, or spider, how similar would they be?
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The starlet sea anemone, Nematostella vectensis, is becoming a leading cnidarian lab model as unlike many other cnidarian species it can be grown in the lab throughout its life cycle. This makes Nematostella a unique system to study the venom of an animal with a complex life cycle. Another advantage is that the high genetic homogeneity of the common Nematostella lab strain minimizes individual genetic variation, which is far from trivial in most other venomous animals collected from the wild in limited numbers.
These are all valid reasons that support the claim that the Starlet Sea Anemone is a prime model organism for studying the venom of an animal with a complex life cycle.
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- May 2024
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elifesciences.org elifesciences.org
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Lenti-X 293T
DOI: 10.7554/eLife.86727.2
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- RRID:AB_11129865
- RRID:AB_2338512
- RRID:Addgene_171729
- RRID:SCR_012919
- RRID:AB_628082
- RRID:Addgene_12259
- RRID:Addgene_12260
- RRID:SCR_017048
- RRID:AB_2797903
- RRID:SCR_011843
- RRID:Addgene_52963
- RRID:AB_532256
- RRID:AB_2118009
- RRID:AB_10658965
- RRID:AB_823586
- RRID:SCR_008520
- RRID:AB_2534069
- RRID:SCR_016863
- RRID:SCR_002380
- RRID:SCR_015723
- RRID:AB_2646731
- RRID:SCR_011841
- RRID:AB_297271
- RRID:CVCL_2119
- RRID:SCR_006646
- RRID:SCR_019318
- RRID:AB_2099233
- RRID:CVCL_1926
- RRID:SCR_020938
- RRIDCUR:Unresolved
- RRID:SCR_016948
- RRID:SCR_014353
- RRID:SCR_014485
- RRID:AB_2534095
- RRID:SCR_015687
- RRID:Addgene_52962
- RRID:SCR_018361
- RRID:SCR_014329
- RRID:CVCL_0004
- RRID:SCR_022512
- RRID:CVCL_0064
- RRID:SCR_000305
- RRID:SCR_004463
- RRID:SCR_001905
- RRID:SCR_013049
- RRID:SCR_002285
Annotators
URL
-
-
elifesciences.org elifesciences.org
-
JAX:005703
DOI: 10.7554/eLife.92673.3
Resource: (IMSR Cat# JAX_005703,RRID:IMSR_JAX:005703)
Curator: @scibot
SciCrunch record: RRID:IMSR_JAX:005703
-
JAX:101043
DOI: 10.7554/eLife.92673.3
Resource: (IMSR Cat# JAX_101043,RRID:IMSR_JAX:101043)
Curator: @scibot
SciCrunch record: RRID:IMSR_JAX:101043
-
JAX:007906
DOI: 10.7554/eLife.92673.3
Resource: (IMSR Cat# JAX_007906,RRID:IMSR_JAX:007906)
Curator: @scibot
SciCrunch record: RRID:IMSR_JAX:007906
-
JAX:006054
DOI: 10.7554/eLife.92673.3
Resource: (IMSR Cat# JAX_006054,RRID:IMSR_JAX:006054)
Curator: @scibot
SciCrunch record: RRID:IMSR_JAX:006054
-
JAX:006660
DOI: 10.7554/eLife.92673.3
Resource: (IMSR Cat# JAX_006660,RRID:IMSR_JAX:006660)
Curator: @scibot
SciCrunch record: RRID:IMSR_JAX:006660
-
RRID:AB_141780
DOI: 10.7554/eLife.92673.3
Resource: (Molecular Probes Cat# A-21424, RRID:AB_141780)
Curator: @scibot
SciCrunch record: RRID:AB_141780
-
RRID:AB_2576217
DOI: 10.7554/eLife.92673.3
Resource: (Thermo Fisher Scientific Cat# A-11034, RRID:AB_2576217)
Curator: @scibot
SciCrunch record: RRID:AB_2576217
-
RRID:AB_303395
DOI: 10.7554/eLife.92673.3
Resource: (Abcam Cat# ab290, RRID:AB_303395)
Curator: @scibot
SciCrunch record: RRID:AB_303395
-
RRID:AB_2633281
DOI: 10.7554/eLife.92673.3
Resource: (Thermo Fisher Scientific Cat# A32732, RRID:AB_2633281)
Curator: @scibot
SciCrunch record: RRID:AB_2633281
-
RRID:AB_2534069
DOI: 10.7554/eLife.92673.3
Resource: (Thermo Fisher Scientific Cat# A-11001, RRID:AB_2534069)
Curator: @scibot
SciCrunch record: RRID:AB_2534069
-
RRID:AB_839504
DOI: 10.7554/eLife.92673.3
Resource: (Wako Cat# 019-19741, RRID:AB_839504)
Curator: @scibot
SciCrunch record: RRID:AB_839504
-
RRID:AB_2341188
DOI: 10.7554/eLife.92673.3
Resource: (Cell Signaling Technology Cat# 9661, RRID:AB_2341188)
Curator: @scibot
SciCrunch record: RRID:AB_2341188
-
RRID:AB_2630395
DOI: 10.7554/eLife.92673.3
Resource: (Cell Signaling Technology Cat# 12943, RRID:AB_2630395)
Curator: @scibot
SciCrunch record: RRID:AB_2630395
-
RRID:AB_628422
DOI: 10.7554/eLife.92673.3
Resource: (Santa Cruz Biotechnology Cat# sc-25269, RRID:AB_628422)
Curator: @scibot
SciCrunch record: RRID:AB_628422
-
RRID:AB_2313606
DOI: 10.7554/eLife.92673.3
Resource: (Vector Laboratories Cat# BA-1000, RRID:AB_2313606)
Curator: @scibot
SciCrunch record: RRID:AB_2313606
-
RRID:AB_297840
DOI: 10.7554/eLife.92673.3
Resource: (Abcam Cat# ab112, RRID:AB_297840)
Curator: @scibot
SciCrunch record: RRID:AB_297840
-
RRID:AB_2651127
DOI: 10.7554/eLife.92673.3
Resource: (LI-COR Biosciences Cat# 925-32211, RRID:AB_2651127)
Curator: @scibot
SciCrunch record: RRID:AB_2651127
-
RRID:AB_2651128
DOI: 10.7554/eLife.92673.3
Resource: (LI-COR Biosciences Cat# 925-68070, RRID:AB_2651128)
Curator: @scibot
SciCrunch record: RRID:AB_2651128
-
RRID:AB_309711
DOI: 10.7554/eLife.92673.3
Resource: (Millipore Cat# 05-386, RRID:AB_309711)
Curator: @scibot
SciCrunch record: RRID:AB_309711
-
RRID:AB_2713963
DOI: 10.7554/eLife.92673.3
Resource: (Abcam Cat# ab133474, RRID:AB_2713963)
Curator: @scibot
SciCrunch record: RRID:AB_2713963
-
RRID:AB_2756700
DOI: 10.7554/eLife.92673.3
Resource: (Alomone Labs Cat# ANR-101, RRID:AB_2756700)
Curator: @scibot
SciCrunch record: RRID:AB_2756700
Tags
- RRID:AB_297840
- RRID:AB_303395
- RRID:AB_628422
- RRID:IMSR_JAX:006054
- RRID:AB_141780
- RRID:AB_309711
- RRID:AB_2651127
- RRID:IMSR_JAX:006660
- RRID:AB_2633281
- RRID:IMSR_JAX:005703
- RRID:AB_2651128
- RRID:AB_2630395
- RRID:AB_2313606
- RRID:AB_839504
- RRID:AB_2576217
- RRID:AB_2534069
- RRID:IMSR_JAX:101043
- RRID:AB_2756700
- RRID:IMSR_JAX:007906
- RRID:AB_2341188
- RRID:AB_2713963
Annotators
URL
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elifesciences.org elifesciences.org
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RRID:AB_2534121
DOI: 10.7554/eLife.89424
Resource: (Thermo Fisher Scientific Cat# A-11077, RRID:AB_2534121)
Curator: @scibot
SciCrunch record: RRID:AB_2534121
-
RRID:AB_2864363
DOI: 10.7554/eLife.89424
Resource: (Thermo Fisher Scientific Cat# 21230, RRID:AB_2864363)
Curator: @scibot
SciCrunch record: RRID:AB_2864363
-
RRID:AB_2254298
DOI: 10.7554/eLife.89424
Resource: (Proteintech Cat# 13818-1-AP, RRID:AB_2254298)
Curator: @scibot
SciCrunch record: RRID:AB_2254298
-
RRID:AB_772206
DOI: 10.7554/eLife.89424
Resource: (GE Healthcare Cat# NA934, RRID:AB_772206)
Curator: @scibot
SciCrunch record: RRID:AB_772206
-
RRID:AB_304320
DOI: 10.7554/eLife.89424
Resource: (Abcam Cat# ab4147, RRID:AB_304320)
Curator: @scibot
SciCrunch record: RRID:AB_304320
-
RRID:CVCL_0188
DOI: 10.7554/eLife.89424
Resource: (RCB Cat# RCB0987, RRID:CVCL_0188)
Curator: @scibot
SciCrunch record: RRID:CVCL_0188
-
RRID:AB_10622025
DOI: 10.7554/eLife.89424
Resource: (Cell Signaling Technology Cat# 5174, RRID:AB_10622025)
Curator: @scibot
SciCrunch record: RRID:AB_10622025
-
RRID:AB_2099233
DOI: 10.7554/eLife.89424
Resource: (Cell Signaling Technology Cat# 7074, RRID:AB_2099233)
Curator: @scibot
SciCrunch record: RRID:AB_2099233
-
RRID:AB_2154298
DOI: 10.7554/eLife.89424
Resource: (Cell Signaling Technology Cat# 2756, RRID:AB_2154298)
Curator: @scibot
SciCrunch record: RRID:AB_2154298
-
RRID:AB_2534029
DOI: 10.7554/eLife.89424
Resource: (Thermo Fisher Scientific Cat# A10520, RRID:AB_2534029)
Curator: @anisehay
SciCrunch record: RRID:AB_10563288
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-
elifesciences.org elifesciences.org
-
RRID:SCR_017829
DOI: 10.7554/eLife.89306.2
Resource: University of Virginia School of Medicine Flow Cytometry Core Facility (RRID:SCR_017829)
Curator: @scibot
SciCrunch record: RRID:SCR_017829
Tags
Annotators
URL
-
-
elifesciences.org elifesciences.org
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RRID:AB_2715788
DOI: 10.7554/eLife.84875.2
Resource: (BioLegend Cat# 698301 (also 698302), RRID:AB_2715788)
Curator: @scibot
SciCrunch record: RRID:AB_2715788
-
RRID:AB_221568
DOI: 10.7554/eLife.84875.2
Resource: (Molecular Probes Cat# A-11120, RRID:AB_221568)
Curator: @scibot
SciCrunch record: RRID:AB_221568
-
RRID:AB_477585
DOI: 10.7554/eLife.84875.2
Resource: (Sigma-Aldrich Cat# T6793, RRID:AB_477585)
Curator: @scibot
SciCrunch record: RRID:AB_477585
-
RRID:AB_10638480
DOI: 10.7554/eLife.84875.2
Resource: (Proteintech Cat# 12780-1-AP, RRID:AB_10638480)
Curator: @scibot
SciCrunch record: RRID:AB_10638480
-
RRID:AB_477584
DOI: 10.7554/eLife.84875.2
Resource: (Sigma-Aldrich Cat# T6557, RRID:AB_477584)
Curator: @scibot
SciCrunch record: RRID:AB_477584
-
RRID:AB_537701
DOI: 10.7554/eLife.84875.2
Resource: (Novus Cat# H00001070-M01, RRID:AB_537701)
Curator: @scibot
SciCrunch record: RRID:AB_537701
-
RRID:AB_477583
DOI: 10.7554/eLife.84875.2
Resource: (Sigma-Aldrich Cat# T6199, RRID:AB_477583)
Curator: @scibot
SciCrunch record: RRID:AB_477583
-
RRID:Addgene_52961
DOI: 10.7554/eLife.84875.2
Resource: RRID:Addgene_52961
Curator: @scibot
SciCrunch record: RRID:Addgene_52961
-
RRID:Addgene_87421
DOI: 10.7554/eLife.84875.2
Resource: RRID:Addgene_87421
Curator: @scibot
SciCrunch record: RRID:Addgene_87421
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-
elifesciences.org elifesciences.org
-
RRID:SCR_006525
DOI: 10.7554/eLife.91482
Resource: Picard (RRID:SCR_006525)
Curator: @scibot
SciCrunch record: RRID:SCR_006525
Tags
Annotators
URL
-
-
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
-
RRID:SCR_016263
DOI: 10.7554/eLife.90996
Resource: SymPhoTime 64 (RRID:SCR_016263)
Curator: @scibot
SciCrunch record: RRID:SCR_016263
Tags
Annotators
URL
-
- Apr 2024
-
elifesciences.org elifesciences.org
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RRID:SCR_006971
DOI: 10.7554/eLife.94917.1
Resource: MRtrix (RRID:SCR_006971)
Curator: @scibot
SciCrunch record: RRID:SCR_006971
Tags
Annotators
URL
-
-
elifesciences.org elifesciences.org
-
RRID:SCR_006525
DOI: 10.7554/eLife.93019
Resource: Picard (RRID:SCR_006525)
Curator: @scibot
SciCrunch record: RRID:SCR_006525
Tags
Annotators
URL
-
-
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
-
RRID:AB_2337245
DOI: 10.7554/eLife.91465
Resource: (Jackson ImmunoResearch Labs Cat# 016-170-084, RRID:AB_2337245)
Curator: @scibot
SciCrunch record: RRID:AB_2337245
-
RRID:AB_2337244
DOI: 10.7554/eLife.91465
Resource: (Jackson ImmunoResearch Labs Cat# 016-160-084, RRID:AB_2337244)
Curator: @scibot
SciCrunch record: RRID:AB_2337244
-
RRID:AB_2337246
DOI: 10.7554/eLife.91465
Resource: (Jackson ImmunoResearch Labs Cat# 016-220-084, RRID:AB_2337246)
Curator: @scibot
SciCrunch record: RRID:AB_2337246
-
RRID:AB_162543
DOI: 10.7554/eLife.91465
Resource: (Molecular Probes Cat# A-31572, RRID:AB_162543)
Curator: @scibot
SciCrunch record: RRID:AB_162543
-
RRID:AB_2313596
DOI: 10.7554/eLife.91465
Resource: (Jackson ImmunoResearch Labs Cat# 703-065-155, RRID:AB_2313596)
Curator: @scibot
SciCrunch record: RRID:AB_2313596
-
RRID:AB_2340594
DOI: 10.7554/eLife.91465
Resource: (Jackson ImmunoResearch Labs Cat# 711-066-152, RRID:AB_2340594)
Curator: @scibot
SciCrunch record: RRID:AB_2340594
-
RRID:AB_300798
DOI: 10.7554/eLife.91465
Resource: (Abcam Cat# ab13970, RRID:AB_300798)
Curator: @scibot
SciCrunch record: RRID:AB_300798
-
- Mar 2024
-
elifesciences.org elifesciences.org
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RRID:IMSR_RBRC10723
DOI: 10.7554/eLife.82952
Resource: RRID:IMSR_RBRC10723
Curator: @scibot
SciCrunch record: RRID:IMSR_RBRC10723
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RRID:IMSR_JAX:000664
DOI: 10.7554/eLife.82952
Resource: (IMSR Cat# JAX_000664,RRID:IMSR_JAX:000664)
Curator: @scibot
SciCrunch record: RRID:IMSR_JAX:000664
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-
elifesciences.org elifesciences.org
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HEK293T
DOI: 10.7554/eLife.83725
Resource: (CCLV Cat# CCLV-RIE 1018, RRID:CVCL_0063)
Curator: @AniH
SciCrunch record: RRID:CVCL_0063
Tags
Annotators
URL
-
-
elifesciences.org elifesciences.org
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C57BL/6NRj
DOI: 10.7554/eLife.87592
Resource: RRID:IMSR_RJ:C57BL-6NRJ
Curator: @AniH
SciCrunch record: RRID:IMSR_RJ:C57BL-6NRJ
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RRID:SCR_005223
DOI: 10.7554/eLife.87592
Resource: STRING (RRID:SCR_005223)
Curator: @AniH
SciCrunch record: RRID:SCR_005223
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-
elifesciences.org elifesciences.org
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RRID: AB_449644
DOI: 10.7554/eLife.89453
Resource: (Abcam Cat# ab8224, RRID:AB_449644)
Curator: @AniH
SciCrunch record: RRID:AB_449644
-
RRID: AB_397554
DOI: 10.7554/eLife.89453
Resource: (BD Biosciences Cat# 610153, RRID:AB_397554)
Curator: @AniH
SciCrunch record: RRID:AB_397554
-
RRID: AB_2304437
DOI: 10.7554/eLife.89453
Resource: (R and D Systems Cat# AF3460, RRID:AB_2304437)
Curator: @AniH
SciCrunch record: RRID:AB_2304437
-
RRID: AB_887873
DOI: 10.7554/eLife.89453
Resource: (Synaptic Systems Cat# 131 004, RRID:AB_887873)
Curator: @AniH
SciCrunch record: RRID:AB_887873
-
RRID: AB_477593
DOI: 10.7554/eLife.89453
Resource: (Sigma-Aldrich Cat# T9026, RRID:AB_477593)
Curator: @AniH
SciCrunch record: RRID:AB_477593
-
RRID: AB_2092361
DOI: 10.7554/eLife.89453
Resource: (Thermo Fisher Scientific Cat# MA1-046, RRID:AB_2092361)
Curator: @AniH
SciCrunch record: RRID:AB_2092361
-
RRID: AB_306298
DOI: 10.7554/eLife.89453
Resource: (Abcam Cat# ab8135, RRID:AB_306298)
Curator: @AniH
SciCrunch record: RRID:AB_306298
-
RRID: AB_2630395
DOI: 10.7554/eLife.89453
Resource: (Cell Signaling Technology Cat# 12943, RRID:AB_2630395)
Curator: @AniH
SciCrunch record: RRID:AB_2630395
-
RRID: AB_2307321
DOI: 10.7554/eLife.89453
Resource: (Cell Signaling Technology Cat# 9255, RRID:AB_2307321)
Curator: @AniH
SciCrunch record: RRID:AB_2307321
-
RRID: AB_2250373
DOI: 10.7554/eLife.89453
Resource: (Cell Signaling Technology Cat# 9252, RRID:AB_2250373)
Curator: @AniH
SciCrunch record: RRID:AB_2250373
-
RRID: AB_839504
DOI: 10.7554/eLife.89453
Resource: (Wako Cat# 019-19741, RRID:AB_839504)
Curator: @AniH
SciCrunch record: RRID:AB_839504
-
RRID: AB_887730
DOI: 10.7554/eLife.89453
Resource: (Synaptic Systems Cat# 160 003, RRID:AB_887730)
Curator: @AniH
SciCrunch record: RRID:AB_887730
-
RRID: AB_310288
DOI: 10.7554/eLife.89453
Resource: (Millipore Cat# 06-896, RRID:AB_310288)
Curator: @AniH
SciCrunch record: RRID:AB_310288
-
RRID: AB_2619838
DOI: 10.7554/eLife.89453
Resource: (Synaptic Systems Cat# 147 002, RRID:AB_2619838)
Curator: @AniH
SciCrunch record: RRID:AB_2619838
-
RRID: AB_2630358
DOI: 10.7554/eLife.89453
Resource: (Abcam Cat# ab181602, RRID:AB_2630358)
Curator: @AniH
SciCrunch record: RRID:AB_2630358
-
RRID: AB_354610
DOI: 10.7554/eLife.89453
Resource: (R and D Systems Cat# AF1118, RRID:AB_354610)
Curator: @AniH
SciCrunch record: RRID:AB_354610
-
RRID: AB_355734
DOI: 10.7554/eLife.89453
Resource: (R and D Systems Cat# AF948, RRID:AB_355734)
Curator: @AniH
SciCrunch record: RRID:AB_355734
-
RRID: AB_2661779
DOI: 10.7554/eLife.89453
Resource: (Synaptic Systems Cat# 141 016, RRID:AB_2661779)
Curator: @AniH
SciCrunch record: RRID:AB_2661779
-
RRID: AB_2917960
DOI: 10.7554/eLife.89453
Resource: (Novus Cat# NBP2-62566, RRID:AB_2917960)
Curator: @AniH
SciCrunch record: RRID:AB_2917960
-
RRID: AB_2564653
DOI: 10.7554/eLife.89453
Resource: (BioLegend Cat# 803001, RRID:AB_2564653)
Curator: @AniH
SciCrunch record: RRID:AB_2564653
Tags
- RRID:AB_2630358
- RRID:AB_2250373
- RRID:AB_449644
- RRID:AB_354610
- RRID:AB_306298
- RRID:AB_2917960
- RRID:AB_355734
- RRID:AB_887873
- RRID:AB_2304437
- RRID:AB_2619838
- RRID:AB_477593
- RRID:AB_2092361
- RRID:AB_2564653
- RRID:AB_2307321
- RRID:AB_2630395
- RRID:AB_839504
- RRID:AB_397554
- RRID:AB_887730
- RRID:AB_310288
- RRID:AB_2661779
Annotators
URL
-
-
elifesciences.org elifesciences.org
-
Addgene26969-AAV9
DOI: 10.7554/eLife.91153
Resource: RRID:Addgene_26969
Curator: @AniH
SciCrunch record: RRID:Addgene_26969
-
Addgene100834-AAV9
DOI: 10.7554/eLife.91153
Resource: RRID:Addgene_100834
Curator: @AniH
SciCrunch record: RRID:Addgene_100834
-
Jackson Laboratories022730
DOI: 10.7554/eLife.91153
Resource: (IMSR Cat# JAX_022730,RRID:IMSR_JAX:022730)
Curator: @AniH
SciCrunch record: RRID:IMSR_JAX:022730
-
Jackson Laboratories031332
DOI: 10.7554/eLife.91153
Resource: (IMSR Cat# JAX_031332,RRID:IMSR_JAX:031332)
Curator: @AniH
SciCrunch record: RRID:IMSR_JAX:031332
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-
elifesciences.org elifesciences.org
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5726
-
99
-
94697
DOI: 10.7554/eLife.84382
Resource: RRID:BDSC_94697
Curator: @Naa003
SciCrunch record: RRID:BDSC_94697
-
7144
-
9610
-
40826
DOI: 10.7554/eLife.84382
Resource: (BDSC Cat# 40826,RRID:BDSC_40826)
Curator: @Naa003
SciCrunch record: RRID:BDSC_40826
-
31664
DOI: 10.7554/eLife.84382
Resource: (BDSC Cat# 31664,RRID:BDSC_31664)
Curator: @Naa003
SciCrunch record: RRID:BDSC_31664
-
31469
DOI: 10.7554/eLife.84382
Resource: (BDSC Cat# 31469,RRID:BDSC_31469)
Curator: @Naa003
SciCrunch record: RRID:BDSC_31469
-
35787
DOI: 10.7554/eLife.84382
Resource: (BDSC Cat# 35787,RRID:BDSC_35787)
Curator: @Naa003
SciCrunch record: RRID:BDSC_35787
-
24370
DOI: 10.7554/eLife.84382
Resource: RRID:BDSC_24370
Curator: @Naa003
SciCrunch record: RRID:BDSC_24370
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5430
DOI: 10.7554/eLife.84382
Resource: (BDSC Cat# 5430,RRID:BDSC_5430)
Curator: @Naa003
SciCrunch record: RRID:BDSC_5430
-