- Sep 2024
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Disease: Von-willebrand Disorder
Patient: 21 yo, female, Italian descent
Variant: VWF NM_000552.5 c:C3379 > T p.(P1127S), homozygous
Heterozygous and Homozygous polymorphic variant in exon 25
Phenotypes: Bleeding Score System (BSS) = 3 minor bruising normal menstrual bleeding
Family: (father paternity confirmed) Father suffered from rectorrhagia for rectal polyps Mother (same variant, heterozygous) has heavy menstrual bleeding, epistaxis events up to age 30, BBS= 2
Present in dbSNP (rs139579968) MAF in European pop = 0.0001-0.0004
Present in gnomAD, said to be present in 2 transcripts in VWF 40 alleles are present
Predictions: listed with PolyPhen-2 and SIFT = probably damaging to protein expression/function
CADD (score =33) and REVEL(score = 0.748) suggest deleterious effect of pathogenic variant
I-TASSER showed large difference in 3D configuration of sequences differing by a single amino acid.
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- Jul 2024
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docdrop.org docdrop.org
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the amount of your LDL isn't the whole story the quality of your LDL cholesterol particles is very important in this
for - health - heart - LDL score
health - heart - LDL score - The AMOUNT of your LDL score is not as important as - The QUALITY of your LDL score - ALL high LDL isn't dangerous
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- May 2024
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schottarchiv-digital.de schottarchiv-digital.de
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Herr Gott dich loben alle wir
Genfer Melodie zum 134. Psalm / Old 100th: https://www.wikidata.org/wiki/Q17012865
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- Nov 2023
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www.youtube.com www.youtube.com
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blah. this surveillance system is one big personality test.<br /> the problem is, they do not want a balance of all personality types or "natural order",<br /> but they do a one-sided selection by personality type.<br /> aka socialdarwinism, socialism, survival of the social, social credit score, civilization, high culture, progress, "made order", human laws, human rights, humanism, ...
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- May 2023
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viva.pressbooks.pub viva.pressbooks.pub
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viva.pressbooks.pub viva.pressbooks.pub
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viva.pressbooks.pub viva.pressbooks.pub
- Jun 2022
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If we don't create good large-scale aggregates of social data, then we risk ceding market share to opaque and centralized social credit scores instead.
Vitalik argues that if we don't create good decentralized social credit score systems, that vacuum will be filled by centralized alternatives.
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- May 2022
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A platform can use all available signals to judge who should have promotion and privileges on the platform, including giving more access and amplification to those who have shown a consistent history of positively engaging with others. And those who misbehave on the platform would be managed with a community management strategy that's informed by the principles of restorative justice, incentivizing good behaviors while also taking into account a person's history of community contributions on other platforms as well.
Using Outside Signals to Judge Promotion/Privileges
The linked "community management strategy" post is about using signals outside our system to help adjudicate the actions on our own network. This seems strikingly close to the "social credit score" that is being tried in some cities in China. And that is pretty uncomfortable.
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- Jun 2021
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psyarxiv.com psyarxiv.com
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Agarwal, A. (2021). COVID19 Stress Scale—Nepali Version. PsyArXiv. https://doi.org/10.31234/osf.io/374hx
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- Oct 2020
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www.bmj.com www.bmj.com
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Knight, S. R., Ho, A., Pius, R., Buchan, I., Carson, G., Drake, T. M., Dunning, J., Fairfield, C. J., Gamble, C., Green, C. A., Gupta, R., Halpin, S., Hardwick, H. E., Holden, K. A., Horby, P. W., Jackson, C., Mclean, K. A., Merson, L., Nguyen-Van-Tam, J. S., … Harrison, E. M. (2020). Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: Development and validation of the 4C Mortality Score. BMJ, 370. https://doi.org/10.1136/bmj.m3339
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- Sep 2020
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www.euromomo.eu www.euromomo.eu
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Graphs and maps from EUROMOMO. (n.d.). EUROMOMO. Retrieved September 18, 2020, from https://euromomo.eu/dev-404-page/
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Is the 4C Mortality Score fit for purpose? Some comments and concerns. (2020). https://www.bmj.com/content/370/bmj.m3339/rr-3
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- Jul 2020
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Bernabeu, P. (2020). Dutch modality exclusivity norms for 336 properties and 411 concepts. https://doi.org/10.31234/osf.io/s2c5h
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- Jun 2020
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www.reddit.com www.reddit.com
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BehSciMeta repost. (2020, June 17). "Reproducibility scores for behavioural science: what are the merits and drawbacks?" Reddit. https://www.reddit.com/r/BehSciMeta/comments/har2np/reproducibility_scores_for_behavioural_science/
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- Mar 2020
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Local file Local file
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The scoring function was designed to encourage thematch between atoms with similar electrostatic charge,giving an additional bonus to atom pairs bearing a non-zeroformal charge of the same sign and a penalty to oppositelycharged centres
the score will be high if atom with similar electrostatic charge is aligned.
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- Nov 2018
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www.voterchoicema.org www.voterchoicema.org
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On the theoretical front, approval and score voting fail a critical test that voting theorists call the majority criterion.
"Failing the majority criterion" is actually a good thing, because these systems find the candidate who is most acceptable to the entire population, rather than the candidate who is most acceptable to half of the population.
Majoritarianism that ignores the desires of half of the population leads to adversarial politics, polarization, and eventually even to violence and civil war.
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www.the-hospitalist.org www.the-hospitalist.org
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And earlier this year, CMS announced that by this time next year hospitalists would be assigned their own specialty designation code. SHM’s Public Policy Committee lobbied for the move for more than two years.
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By 2007, SHM had launched Project BOOST (Better Outcomes by Optimizing Safe Transitions), an award-winning mentored-implementation program to reduce LOS, adverse events, and unnecessary 30-day readmissions. Other mentored-implementation programs followed. The Glycemic Control Mentored Implementation (GCMI) program focuses on preventing hypoglycemia, while the Venous Thromboembolism Prevention Collaborative (VTE PC) seeks to give practical assistance on how to reduce blood clots via a VTE prevention program
Other SHM Mentored Implementation programs -
- Atul Gawande
- I-PASS
- PFC I-PASS Link this to
- Dissemination and implementation of research findings
- Twenty years since to err is human
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In 2012, SHM earned the 2011 John M. Eisenberg Patient Safety and Quality Award for Innovation in Patient Safety and Quality at the National Level, thanks to its mentored-implementation programs. SHM was the first professional society to earn the award, bestowed by the National Quality Forum (NQF) and The Joint Commission.
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By 2003, the term “hospitalist” had become ubiquitous enough that NAIP was renamed the Society of Hospital Medicine
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John Nelson, MD, MHM, and Winthrop Whitcomb, MD, MHM, founded the National Association of Inpatient Physicians (NAIP) a year after the NEJM paper, they promoted and held a special session at UCSF’s first “Management of the Hospitalized Patient” conference in April 1997
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- Jul 2018
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meity.gov.in meity.gov.in
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where applicable, any rating in the form of a data trust score that may be assignedto the data fiduciary under section 35;and
A Data Trust score. Thankfully, it isn't mandatory to have a data trust score, which mean that apps and services can exist without there being a trust score
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The best forecasters make lots of precise forecasts and keep track of their performance with a metric such as a Brier score.
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- Apr 2018