9 Matching Annotations
  1. Apr 2026
    1. Urgent treatment for neoplasm consists of (1) cautious use of intravenous diuretics and (2) mediastinal irradiation, starting within 24 hours, with a treatment plan designed to give a high daily dose of radiation but a short total course of therapy to rapidly shrink the local tumor. Intensive radiation therapy combined with chemotherapy will palliate the process in up to 90% of patients. In patients with a subacute presentation, radiation therapy alone usually suffices. Chemotherapy is added if lymphoma or small-cell carcinoma is diagnosed

      endovascular stenting emerging as first-line therapy for rapid symptom relief, while definitive treatment targets the underlying cause

      Glucocorticoids (dexamethasone 4 mg every 6 hours) are commonly prescribed but lack robust supporting data; they may be more beneficial in lymphoma or thymoma and as prophylaxis against radiation-induced edema. [2-4] Importantly, SVC syndrome is no longer considered a medical emergency except in rare cases with life-threatening cerebral edema, laryngeal edema, or altered mental status. When thrombosis is present, catheter-directed thrombolysis or aspiration thrombectomy should be performed within 2-5 days of symptom onset before thrombus organization occurs. [3] The role of long-term anticoagulation after stenting remains unclear, though it is standard when significant thrombosis is present The American College of Chest Physicians recommends obtaining histologic diagnosis before treatment in suspected lung cancer cases, as stenting does not interfere with tissue diagnosis. [2] For small cell lung cancer (SCLC), chemotherapy alone is recommended as first-line treatment given rapid response rates. [2] For non-small cell lung cancer (NSCLC), radiation therapy and/or stent insertion are recommended, with response rates of 59% for chemotherapy and 63% for radiation therapy. [2] Patients with chemotherapy- or radiation-refractory disease should receive vascular stents For device-related thrombosis (catheters, pacemakers), catheter removal should be considered in conjunction with anticoagulation. [4] Endovascular therapy is first-line for device-related obstruction, while surgical bypass may be preferred for mediastinal fibrosis. [7] Both approaches show good mid-term patency, though secondary interventions are common (approximately 27-28%

    Tags

    Annotators

    URL

  2. Jan 2022
  3. Oct 2021
  4. Jul 2020
  5. May 2020
  6. Aug 2016
    1. Page 122

      Borgman on terms used by the humanities and social sciences to describe data and other types of analysis

      humanist and social scientists frequently distinguish between primary and secondary information based on the degree of analysis. Yet this ordering sometimes conflates data, sources, and resources, as exemplified by a report that distinguishes "primary resources, E. G., Books close quotation from quotation secondary resources, eat. Gee., Catalogs close quotation . Resources also categorized as primary or sensor data, numerical data, and field notebooks, all of which would be considered data in the sciences. Rarely would books, conference proceedings, and feces that the report categorizes as primary resources be considered data, except when used for text-or data-mining purposes. Catalogs, subject indices, citation indexes, search engines, and web portals were classified as secondary resources. These are typically viewed as tertiary resources in the library community because they describe primary and secondary resources. The distinctions between data, sources, and resources very by discipline and circumstance. For the purposes of this book, primary resources are data, secondary resources are reports of research, whether publications or intern forms, and tertiary resources are catalogs, indexes, and directories that provide access to primary and secondary resources. Sources are the origins of these resources.

  7. Jul 2016