This negates a key defence commonly cited by trialists and sponsors when facing calls for greater transparency: that journals reject “negative” results. All trials can now be reported, immediately, using clinicaltrials.gov as a first or last resort, if the trialist is willing. The question remains: how can we ensure this is done?
Raises the question about whether regulatory agencies could use annotations, as part of Resource Watch, to question whether data that should have been released was released.