- Last 7 days
Sleepiness and neck circumference were significantly reduced only in the diet group (p = .007 and p < .001 for the time × group interactions, respectively).
Fascinating. Neck circumference suggests that sodium intake may indeed be the significant dietary factor. The recommended diet wasn't even very restricted in sodium.
- Oct 2017
Beta blockers have long been associated with sleep disturbances such as difficulty falling asleep, staying asleep, and insomnia. They have been shown to reduce the production of melatonin via specific inhibition of beta-1 adrenergic receptors. Melatonin is a hormone secreted by the pineal gland in the brain, and helps in maintaining normal circadian rhythms.6,20-21 People with hypertension already have a lower melatonin production rate than those with normal blood pressure.22
The question becomes, then, do beta blockers impair sleep when exogenous melatonin is administered concurrently?
- beta blocker antagonist adrenaline adrenergic blood pressure hypertension heart rate
- melatonin deep sleep quality architecture circadian rythm zeitgeber chronobiology