10,000 Matching Annotations
  1. Jan 2024
    1. increased levels of Aβ triggered by SCFA in vivo are not mediated by major quantitative or qualitative changes in Aβ production

      通过测定一系列与Aβ产生有关的蛋白和合成过程蛋白(APP C端片段C83和C99、负责APP加工的分泌酶(BACE1, ADAM10和γ-分泌酶PSEN1的催化亚基)的蛋白水平、体外细胞添加SCFA后的γ分泌酶活性),确定SCFA不改变Aβ生成,因此推断改变的是沉积和清除过程。

  2. Dec 2023
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  4. Jul 2023
    1. In contrast to visuospatial attention, language function is widely accepted to lateralize to the (dominant) left hemisphere (Friederici, 2017). Tissue damage to the left temporo-parietal cortex has been reported, for decades, to cause impairments of semantic processing – key to reading and other elaborate forms of language comprehension (Binder et al., 2009; Hartwigsen et al., 2016; Seghier, 2013).

      Suggests the [[left hemisphere of the brain]] is the primary part when using language.

  5. Jun 2023
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  11. Dec 2022
  12. Nov 2022
    1. Horizon-scanning activities related to the Antarctic and Southern Ocean (Kennicutt et al., 2014) have also directed funding and policy (Kennicutt et al., 2019), and helped to provide the basis for research roadmaps (Kennicutt et al., 2015

      Exploraciones del Futuro has help to define financiamiento,