7 Matching Annotations
  1. Last 7 days
  2. Sep 2020
  3. Aug 2020
  4. Apr 2020
    1. Wynants, L., Van Calster, B., Bonten, M. M. J., Collins, G. S., Debray, T. P. A., De Vos, M., Haller, M. C., Heinze, G., Moons, K. G. M., Riley, R. D., Schuit, E., Smits, L. J. M., Snell, K. I. E., Steyerberg, E. W., Wallisch, C., & van Smeden, M. (2020). Prediction models for diagnosis and prognosis of covid-19 infection: Systematic review and critical appraisal. BMJ, m1328. https://doi.org/10.1136/bmj.m1328

    1. COVID‐19 prognosis is related to age and sex. The expression of ACE2 decreases with increasing age. ACE2 expression is higher in young people than in elderly individuals and higher in females than in males.11, 12 This pattern does not match the characteristic of severely ill COVID‐19 patients being mostly elderly males. We believe that whether the level of ACE2 expression is high or low is not a key factor affecting the prognosis of patients with COVID‐19. The relationship between sex and prognosis requires additional data to verify.

      some believe that ACe2 level of expression does not correlate covid-19 prognosis

  5. Feb 2015