467 Matching Annotations
  1. May 2023
  2. www.biorxiv.org www.biorxiv.org
    LuminoCell: a versatile and affordable luminometer platform for monitoring in-cell luciferase-based reporters
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    biorxiv.org/content/10.1101/2022.01.28.478134v1
  3. Apr 2023
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    Efficient knock-in method enabling lineage tracing in zebrafish
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    biorxiv.org/content/10.1101/2022.07.15.500272v1
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    The TUDOR domain of SMN is an H3K79me1 histone mark reader
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    biorxiv.org/content/10.1101/2022.10.06.511070v1
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    Preference of CAMSAP3 for microtubules with expanded lattice contributes to stabilization of the minus end
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    biorxiv.org/content/10.1101/2022.08.21.504720v2
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    Analysis of context-specific KRAS-effectors (sub)complexes in Caco-2 cells
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    biorxiv.org/content/10.1101/2022.08.15.503960v1
  8. Mar 2023
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    Peroxisomes contribute to intracellular calcium dynamics
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    biorxiv.org/content/10.1101/2020.09.02.279174v1
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    An extended DNA-free intranuclear compartment organizes centrosomal microtubules in Plasmodium falciparum
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    biorxiv.org/content/10.1101/2021.03.12.435157v2
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    Non-canonical miRNA-RNA base-pairing impedes tumor suppressor activity of miR-16
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    biorxiv.org/content/10.1101/2021.11.30.470499v1
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    The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation, epithelial repair, and tumor growth
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    biorxiv.org/content/10.1101/2022.04.11.487842v1
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    Stepwise progression of beta-selection during T cell development as revealed by histone deacetylation inhibition
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    biorxiv.org/content/10.1101/2021.10.03.462949v4
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    Lack of peroxisomal catalase affects heat shock response in C. elegans
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    biorxiv.org/content/10.1101/2021.07.13.452156v1
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    Lineage Tracing Reveals Fate Bias and Transcriptional Memory in Human B cells
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    biorxiv.org/content/10.1101/2022.07.14.499766v2
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    Critical roles of ICOS in controlling Foxp3-expressing T follicular cell subsets during early-stage germinal center reactions
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    biorxiv.org/content/10.1101/2021.09.14.460384v2
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    The human MRS2 magnesium binding domain is a regulatory feedback switch for channel activity.
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    biorxiv.org/content/10.1101/2022.09.27.509701v1
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    Activation and inhibition of the C-terminal kinase domain of p90 ribosomal S6 kinases
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    biorxiv.org/content/10.1101/2022.02.18.481032v1
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    Segregation of pathways leading to pexophagy
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    biorxiv.org/content/10.1101/2022.11.08.515582v1
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    New algorithms for accurate and efficient de-novo genome assembly from long DNA sequencing reads
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    biorxiv.org/content/10.1101/2022.08.30.505891v1
  21. Feb 2023
  22. www.biorxiv.org www.biorxiv.org
    Adenylyl cyclase 9 is auto-stimulated by its isoform-specific carboxyl terminal domain and equipped with paradigm-switching mechanisms.
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    biorxiv.org/content/10.1101/2022.06.05.494885v3
  23. www.biorxiv.org www.biorxiv.org
    Lung macrophages utilize cathepsin K-dependent phagosomal machinery to degrade intracellular collagen
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    biorxiv.org/content/10.1101/2022.05.16.492085v1
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    SorCS1 inhibits amyloid-β binding to neurexin and rescues amyloid-β-induced synaptic pathology
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    biorxiv.org/content/10.1101/2022.07.26.501499v1
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    The GET pathway serves to activate Atg32-mediated mitophagy by ER targeting of the Ppg1-Far complex
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    biorxiv.org/content/10.1101/2021.09.20.461067v1
  26. www.biorxiv.org www.biorxiv.org
    Human RNA Nm-MTase FTSJ1: new tRNA targets and role in the regulation of brain-specific genes.
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    biorxiv.org/content/10.1101/2021.02.06.430044v4
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    A genome-wide CRISPR functional survey of the human phagocytosis molecular machinery
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    biorxiv.org/content/10.1101/2022.09.08.507072v1
  28. www.biorxiv.org www.biorxiv.org
    Epigenetic signals that direct cell type specific interferon beta response in mouse cells
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    biorxiv.org/content/10.1101/2022.02.26.481127v1
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    Convergent evolution and horizontal gene transfer in Arctic Ocean microalgae
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    biorxiv.org/content/10.1101/2021.07.31.454568v1
  30. Jan 2023
  31. www.biorxiv.org www.biorxiv.org
    Structural and functional characterization of TraI from pKM101 reveals basis for DNA processing
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    biorxiv.org/content/10.1101/2022.06.02.494495v2
  32. www.biorxiv.org www.biorxiv.org
    Membrane cholesterol regulates inhibition and substrate transport by the glycine transporter, GlyT2
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    biorxiv.org/content/10.1101/2022.08.31.506132v1
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    SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis.
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    biorxiv.org/content/10.1101/2022.02.13.480288v1
  34. www.biorxiv.org www.biorxiv.org
    Epigenetic centromere identity is precisely maintained through DNA replication but is uniquely specified among human cells
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    biorxiv.org/content/10.1101/2022.09.07.506974v1
  35. www.biorxiv.org www.biorxiv.org
    Identifying novel regulators of placental development using time series transcriptomic data and network analyses
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    biorxiv.org/content/10.1101/2022.05.17.492330v1
  36. www.biorxiv.org www.biorxiv.org
    De novo discovery of traits co-occurring with chronic obstructive pulmonary disease
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    biorxiv.org/content/10.1101/2022.07.20.500731v1
  37. www.biorxiv.org www.biorxiv.org
    An isoform-specific function of Cdc42 in regulating mammalian Exo70 during axon formation
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    biorxiv.org/content/10.1101/2022.07.01.498448v1
  38. www.biorxiv.org www.biorxiv.org
    Comparative analysis of MERFISH spatial transcriptomics with bulk and single-cell RNA sequencing
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    biorxiv.org/content/10.1101/2022.03.04.483068v3
  39. www.biorxiv.org www.biorxiv.org
    A synergistic activation of RARb and RARg nuclear receptors restores cell-types specialization during stem cells differentiation by hijacking RARa-controlled program
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    biorxiv.org/content/10.1101/2022.05.31.494116v2
  40. www.biorxiv.org www.biorxiv.org
    Nuclear envelope reshaping around the vacuole determines the morphology of the ribosomal DNA
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    biorxiv.org/content/10.1101/2021.06.23.449658v1
  41. www.biorxiv.org www.biorxiv.org
    Porcine intestinal innate lymphoid cells and lymphocyte spatial context revealed through single-cell RNA sequencing
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    biorxiv.org/content/10.1101/2022.01.09.475571v1
  42. www.biorxiv.org www.biorxiv.org
    Sibling rivalry among the ZBTB transcription factor family: homo vs. heterodimers
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    biorxiv.org/content/10.1101/2021.12.17.472994v2
  43. Dec 2022
  44. www.biorxiv.org www.biorxiv.org
    Stage-specific gene and transcript dynamics in human male germ cells
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    biorxiv.org/content/10.1101/2022.03.22.485121v1
  45. earthcommission.org earthcommission.org
    New Earth Commission Working Group to Focus on the Challenges of Cross-Scale Translation - Earth Commission
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    earthcommission.org/news/earth-commission-news/new-earth-commission-working-group-to-focus-on-the-challenges-of-cross-scale-translation/
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    Cdh5-lineage independent origin of dermal lymphatic vessels revealed by temporally restricted lineage tracing
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    biorxiv.org/content/10.1101/2022.06.08.495310v1
  47. www.biorxiv.org www.biorxiv.org
    Endoplasmic Reticulum membranes are continuously required to maintain mitotic spindle size and forces
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    biorxiv.org/content/10.1101/2022.05.14.491942v1
  48. www.biorxiv.org www.biorxiv.org
    Genome-wide Profiling of Histone Modifications in Plasmodium falciparum using CUT&RUN.
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    biorxiv.org/content/10.1101/2022.08.01.502378v2
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    Systematic analysis of ADP-ribose detection reagents and optimisation of sample preparation to detect ADP-ribosylation in vitro and in cells
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    biorxiv.org/content/10.1101/2022.02.22.481411v1
  50. www.biorxiv.org www.biorxiv.org
    Drosophila pVALIUM10 TRiP RNAi lines cause undesired silencing of Gateway-based transgenes
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    biorxiv.org/content/10.1101/2022.08.12.503771v2
  51. Nov 2022
  52. www.biorxiv.org www.biorxiv.org
    Actin binding domain of Rng2 strongly inhibits actin movement on myosin II HMM through structural changes of actin filaments
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    biorxiv.org/content/10.1101/2020.04.14.041046v4
  53. www.biorxiv.org www.biorxiv.org
    Miro GTPase domains regulate assembly of the mitochondrial motor-adaptor complex
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    biorxiv.org/content/10.1101/2022.05.13.491728v1
  54. www.biorxiv.org www.biorxiv.org
    Improving the computation efficiency of polygenic risk score modeling: Faster in Julia
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    biorxiv.org/content/10.1101/2021.12.27.474263v1
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    Structure of mammalian V-ATPase with the TLDc domain protein mEAK7 bound
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    biorxiv.org/content/10.1101/2021.11.03.466369v2
  56. www.biorxiv.org www.biorxiv.org
    Profiling subcellular localization of nuclear-encoded mitochondrial gene products in zebrafish
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    biorxiv.org/content/10.1101/2021.12.22.473872v1
  57. Oct 2022
  58. www.biorxiv.org www.biorxiv.org
    https://biorxiv.org/cgi/content/10.1101/2022.03.06.483172
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    biorxiv.org/content/10.1101/2022.03.06.483172v1
  59. www.biorxiv.org www.biorxiv.org
    Replication-associated inversions are the dominant form of bacterial chromosome structural variation
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    biorxiv.org/content/10.1101/2022.02.15.480581v1
  60. www.biorxiv.org www.biorxiv.org
    Contribution of the Golgi apparatus in morphogenesis of a virus induced cytopathic vacuolar system
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    biorxiv.org/content/10.1101/2022.03.14.484265v1
  61. www.biorxiv.org www.biorxiv.org
    Regulation of Liprin-α phase separation by CASK is disrupted by a mutation in its CaM kinase domain
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    biorxiv.org/content/10.1101/2022.04.21.489014v1
  62. www.biorxiv.org www.biorxiv.org
    Gain-of-function genetic screens in human cells identify SLC transporters overcoming environmental nutrient restrictions
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    biorxiv.org/content/10.1101/2022.04.03.486870v1
  63. www.biorxiv.org www.biorxiv.org
    Synthetic evolution of herbicide resistance using a T7 RNAP-based random DNA base editor
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    biorxiv.org/content/10.1101/2021.11.30.470689v1
  64. www.biorxiv.org www.biorxiv.org
    Evaluation of CA repeat arrays as targets for MeCP2 function in the brain
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    biorxiv.org/content/10.1101/2022.04.26.489598v2
  65. Sep 2022
  66. www.biorxiv.org www.biorxiv.org
    Meiotic DNA breaks activate a streamlined phospho-signaling response that largely avoids protein level changes
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    biorxiv.org/content/10.1101/2022.02.24.481857v1
  67. www.biorxiv.org www.biorxiv.org
    Human gene function publications that describe wrongly identified nucleotide sequence reagents are unacceptably frequent within the genetics literature
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    biorxiv.org/lookup/doi/10.1101/2021.07.29.453321
  68. Aug 2022
  69. www.biorxiv.org www.biorxiv.org
    Decreasing pdzd8-mediated mitochondrial-ER contacts in neurons improves fitness by increasing mitophagy
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    biorxiv.org/content/10.1101/2020.11.14.382861v1
  70. www.biorxiv.org www.biorxiv.org
    Islet Gene View - a tool to facilitate islet research
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    biorxiv.org/content/10.1101/435743v3
  71. www.biorxiv.org www.biorxiv.org
    Resolution of the curse of dimensionality in single-cell RNA sequencing data analysis
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    biorxiv.org/content/10.1101/2022.05.02.490246v1
  72. www.biorxiv.org www.biorxiv.org
    CFTR modulator response measurements in subjects with cystic fibrosis using 2D differentiated nasal epithelia converted into spheroids
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    biorxiv.org/content/10.1101/2021.07.20.453105v2
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    A minimal hepatocyte growth factor mimic acting as a powerful agonist of the MET receptor tyrosine kinase for regeneration of epithelial tissues and organs.
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    biorxiv.org/content/10.1101/2020.07.20.212654v3
  74. www.biorxiv.org www.biorxiv.org
    Drosophila insulator proteins exhibit in-vivo liquid-liquid phase separation properties
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    biorxiv.org/content/10.1101/2022.05.27.493687v1
  75. www.biorxiv.org www.biorxiv.org
    ScRNA-seq Expression of APOC2 and IFI27 Identifies Four Families of Alveolar Macrophage Superclusters in Cystic Fibrosis and Healthy BALF
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    biorxiv.org/content/10.1101/2022.01.30.478325v3
  76. www.biorxiv.org www.biorxiv.org
    ERK2 MAP kinase regulates SUFU binding by multisite phosphorylation of GLI1
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    biorxiv.org/content/10.1101/2021.12.22.473898v2
  77. Jul 2022
  78. www.biorxiv.org www.biorxiv.org
    LncRNA RUS shapes the gene expression program towards neurogenesis
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    biorxiv.org/content/10.1101/2022.02.17.480853v1
  79. Jun 2022
  80. www.civicsoftechnology.org www.civicsoftechnology.org
    Whose interests do teaching machines serve? — Civics of Technology
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    civicsoftechnology.org/blog/whose-interests-do-teaching-machines-serve
  81. www.biorxiv.org www.biorxiv.org
    Negative curvature-promoting lipids instruct nuclear ingression of low autophagic potential vacuoles
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    biorxiv.org/content/10.1101/2021.06.26.450031v1
  82. www.biorxiv.org www.biorxiv.org
    OXSR1 inhibits inflammasome activation by limiting potassium efflux during mycobacterial infection
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    biorxiv.org/content/10.1101/2021.04.21.440692v1
  83. www.biorxiv.org www.biorxiv.org
    Genetic and compound screens uncover factors modulating cancer cell response to indisulam
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    biorxiv.org/content/10.1101/2021.12.20.473451v1
  84. www.biorxiv.org www.biorxiv.org
    Map7D2 and Map7D1 facilitate microtubule stabilization through distinct mechanisms to control cell motility and neurite outgrowth.
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    biorxiv.org/content/10.1101/2021.10.27.466197v3
  85. May 2022
  86. www.biorxiv.org www.biorxiv.org
    Molecular insights into RNA recognition and gene regulation by the TRIM-NHL protein Mei-P26
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    biorxiv.org/content/10.1101/2021.09.20.461029v1
  87. Apr 2022
  88. www.biorxiv.org www.biorxiv.org
    Tricalbin proteins regulate plasma membrane phospholipid homeostasis
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    biorxiv.org/content/10.1101/2021.06.04.447076v1
  89. www.biorxiv.org www.biorxiv.org
    Polycomb Group Ring Finger Protein 6 suppresses Myc-induced lymphomagenesis
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    biorxiv.org/content/10.1101/2021.12.02.470967v1
  90. www.biorxiv.org www.biorxiv.org
    Quantitative analysis of nuclear pore complex organization in Schizosaccharomyces pombe
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    biorxiv.org/content/10.1101/2021.08.11.455278v1
  91. www.biorxiv.org www.biorxiv.org
    TET2-mediated epigenetic reprogramming of breast cancer cells impairs lysosome biogenesis
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    biorxiv.org/content/10.1101/2021.10.27.466063v1
  92. www.biorxiv.org www.biorxiv.org
    https://biorxiv.org/cgi/content/10.1101/2021.10.18.464926
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    biorxiv.org/content/10.1101/2021.10.18.464926v1
  93. www.biorxiv.org www.biorxiv.org
    Conserved exchange of paralog proteins during neuronal differentiation
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    biorxiv.org/content/10.1101/2021.07.22.453347v1
  94. Mar 2022
  95. www.biorxiv.org www.biorxiv.org
    AGO1 regulates major satellite transcripts and H3K9me3 distribution at pericentromeric regions in mESCs
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    biorxiv.org/content/10.1101/2021.07.26.453733v2
  96. www.biorxiv.org www.biorxiv.org
    GROWTH-RATE DEPENDENT AND NUTRIENT-SPECIFIC GENE EXPRESSION RESOURCE ALLOCATION IN FISSION YEAST
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    biorxiv.org/content/10.1101/2021.03.16.435638v1
  97. www.biorxiv.org www.biorxiv.org
    The expression of essential selenoproteins during zebrafish development requires SECIS binding protein 2-like
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    biorxiv.org/content/10.1101/2021.11.01.466845v1
  98. www.biorxiv.org www.biorxiv.org
    Stress-induced tyrosine phosphorylation of RtcB modulates IRE1 activity and signaling outputs.
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    biorxiv.org/content/10.1101/2020.03.02.972950v5
  99. www.biorxiv.org www.biorxiv.org
    ETV2 regulates PARP-1 binding protein to induce ER stress-mediated cell death in tuberin-deficient cells
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    biorxiv.org/content/10.1101/2021.11.08.467714v1
  100. www.biorxiv.org www.biorxiv.org
    Quantitative Profiling of Adaptation to Cyclin E Overproduction
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    biorxiv.org/content/10.1101/2021.07.26.453751v3
  101. www.biorxiv.org www.biorxiv.org
    https://biorxiv.org/cgi/content/10.1101/2021.09.08.459430
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    biorxiv.org/content/10.1101/2021.09.08.459430v1
  102. www.biorxiv.org www.biorxiv.org
    https://biorxiv.org/cgi/content/10.1101/2021.04.23.440619
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  108. www.mediamatters.org www.mediamatters.org
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      Fox News goes all-in promoting anti-vaccine mandate Canadian truckers. (n.d.). Media Matters for America. Retrieved February 11, 2022, from https://www.mediamatters.org/coronavirus-covid-19/fox-news-goes-all-promoting-anti-vaccine-mandate-canadian-truckers

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  155. Jun 2021
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      G7 support for pharma monopolies is putting millions of lives at risk | Amnesty International. (n.d.). Retrieved June 12, 2021, from https://www.amnesty.org/en/latest/news/2021/06/g7-support-for-pharma-monopolies-putting-millions-of-lives-at-risk/

      is:webpage lang:en COVID-19 G7 G7 Leaders' Summit People's Vaccine Alliance vaccine government UK patent waiving resources campaign vaccine inequity inequity health inequality public health vaccine technology vaccine production funding COVAX pharmaceutical corporation supply finance intellectual property
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  157. May 2021
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  161. Apr 2021
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  172. Feb 2021
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  188. Oct 2020
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    A time resolved interaction analysis of Bem1 reconstructs the flow of Cdc42 during polar growth
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    An evolutionary approach to systematic discovery of novel deubiquitinases, applied to Legionella
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  198. Jul 2020
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    An unexpected contribution of lincRNA splicing to enhancer function.
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    Small molecule inhibitors and a kinase-dead expressing mouse model demonstrate that the kinase activity of Chk1 is essential for mouse embryos and cancer cells
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    biorxiv.org/content/10.1101/2020.01.21.913467v1
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    Lipid-associated PML domains regulate CCTα, Lipin1 and lipid homeostasis
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    biorxiv.org/content/10.1101/2020.03.10.986380v1
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    Mitochondrial fusion defects caused by CMT2A disease-associated variants of Mfn2
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    biorxiv.org/content/10.1101/651877v2
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    Pleiotropic requirements for human TDP-43 in the regulation of cell and organelle homeostasis
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    biorxiv.org/content/10.1101/560144v1
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    A key region of molecular specificity orchestrates unique ephrin-B1 utilization by Cedar virus
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    Evaluation of colorectal cancer subtypes and cell lines using deep learning
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    Pseudomonas aeruginosa lectin LecB impairs keratinocyte fitness by abrogating growth factor signalling
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  207. Jun 2020
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    Plant-microbe co-evolution: allicin resistance in a Pseudomonas fluorescens strain (PfAR-1) isolated from garlic
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    Ubiquitin and SUMO conjugation as biomarkers of Acute Myeloid Leukemias response to chemotherapies
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    biorxiv.org/content/10.1101/825182v1
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    Dynamic changes in the regulatory T cell heterogeneity and function by murine IL-2 mutein
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  211. www.biorxiv.org www.biorxiv.org
    BACH family members regulate angiogenesis and lymphangiogenesis by modulating VEGFC expression
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    biorxiv.org/content/10.1101/2019.12.13.876268v2
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    The structure of SALSA/DMBT1 SRCR domains reveal the conserved ligand-binding mechanism of the ancient SRCR-fold
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  213. Mar 2020
  214. www.digital-democracy.org www.digital-democracy.org
    Towards a Technology of Solidarity: 10 lessons from Dd's first 10 years
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    1. almereyda 07 Mar 2020
      10. Ally is a Verb Solidarity is an ongoing process, and ally is a verb. Showing up in a good way is something we continually practice, not a destination where we arrive. This is not our unique insight - the concept of ally being a verb, not a noun, has a long history in social justice spaces, and it’s one worth highlighting. When we think of ourselves as “allies” (nouns) we can get complacent by thinking we have arrived, or we can get fragile when we make mistakes that make us question our status as “allies.” When instead we see ourselves as practicing allyship with frontline communities, then we recognize that our goal is to continually listen, learn from and take action in solidarity with our partners.
      alliance
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  215. Nov 2019
  216. www.biorxiv.org www.biorxiv.org
    TAF-ChIP: An ultra-low input approach for genome wide chromatin immunoprecipitation assay
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    biorxiv.org/content/10.1101/299727v4
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    Unfolded protein-independent IRE1 activation contributes to multifaceted developmental processes in Arabidopsis
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    Resolving kinesin stepping: one head at a time
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    Detecting Novel Sequence Signals in Targeting Peptides Using Deep Learning
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    Sufficiency analysis of estrogen responsive enhancers using synthetic activators
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    Mechanistic Insights into the Protective Roles of Polyphosphate Against Amyloid Cytotoxicity
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  222. Sep 2019
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    Endogenous RNAi pathway evolutionarily shapes the destiny of the antisense lncRNAs transcriptome
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    let-7 controls the transition to adulthood by releasing select transcriptional regulators from repression by LIN41
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    Ncl1 mediated metabolic rewiring is critical during metabolic stress
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    biorxiv.org/content/10.1101/529578v3
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    Kinesin-8B controls basal body function and flagellum formation and is key to malaria parasite transmission
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    XIAP controls RIPK2 signaling by preventing its deposition in speck-like structures
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    Tumor-Intrinsic Response to IFNgamma Shapes the Tumor Microenvironment and Anti-PD-1 Response in NSCLC
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    The WT1-BASP1 complex is required to maintain the differentiated state of taste receptor cells
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    Molecular characterization of Chlamydomonas reinhardtii telomeres and telomerase mutants
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    Molecular characterization of CHAD domains as inorganic polyphosphate binding modules
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    Hierarchical organization of the human cell from a cancer coessentiality network
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