Since the inception of online gambling, internet accesshas increased dramatically, allowing more people to gam-ble online
It is precisely the expansion of the internet's scale that has led to the development of online gambling.
Since the inception of online gambling, internet accesshas increased dramatically, allowing more people to gam-ble online
It is precisely the expansion of the internet's scale that has led to the development of online gambling.
the dark underbelly of capitalism, its backstage operations where cheap and irre-gular labour is used up in the search for hyperprofit’
There has to be a loser in capitalism and racial lines present a very easy way to pick a loser
and racismenshrines the inequalities that capitalism requires.
bar
They foundwork in one of the most devalued spheres of labour, domestic service
To tie into other reading, they might have had skills that transfered from their own domestic life
Subsequently, they helped other women tomigrate.
I'm so interested in this idea of chain migration and what avenues people use to do it. Like is it because there are existing pathways like physically,m or just rumour brings people to the same place.
The sampling framework employed a multistage stratified random sampling procedure to ensure comprehensive rep-resentation across educational contexts. Initial stratification criteria included grade level (junior and senior secondary),school type (public and private institutions), and geographic location (urban and suburban areas), with probability pro-portional to size sampling within each stratum.
Another option for a follow-up article could be to delve into these categories; it would be interesting to see what differences, if any, exist regarding AI application in secondary education contexts.
The conceptualization and empirical measurement of innovation ability has emerged as a critical domain within educa-tional research, particularly regarding technological integration.
I think that this, as one of the three points of interest identified in this study, is a key point. It is important for students to be able to use and adapt technology in any field. While AI may have negatives, I would argue it is more important to find effective ways to integrate it into the classroom instead of just hoping students will not use it.
Contemporary research has particularly emphasized distance learning applications, as evidenced by Mijwil et al.‘s[27] mixed-methods investigation of AI-enhanced remote education.
I presume the implication is that in instances where students cannot engage in a face-to-face classroom experience, AI may be able to help with learning and answer questions on-demand. However, I definitely think this presents an equal number of challenges as it does opportunities--as AI is known to have "hallucinations" and cite nonexistent sources or present false information, how would students be able to verify what they read? Will students using AI in these contexts undermine research skills? How can these challenges be combated?
The findings hold particular relevance in the current educational context where generative AI technologies are rapidlytransforming pedagogical practices and learning modalities, offering a timely contribution to both the scholarly discourseand educational practice.
While I agree that this article is timely, I wonder how research into this topic will evolve over time since it is still relatively new. I think this leaves room for follow up once more data can be collected and the long-term implications can be more clearly determined.
Within thiscontext, generative AI—defined as AI systems capable of producing, manipulating,and analyzing content across multiple modalities—represents a fundamental par-adigm shift in educational technology [6]. This shift manifests in the transformationof how students interact with information, construct knowledge, and develop criticalcompetencies, necessitating systematic examination of educational innovations [7].
I think this sentence is a key point and introduces why this is a relevant and necessary topic of study for education.
As generative artificial intelligence (AI) rapidly transforms educational landscapes,understanding its impact on students’ core competencies has become increasinglycritical for educators and policymakers.
I think AI has definitely become an important consideration in the classroom regardless of subject area. As with the introduction of more affordable handheld calculators into schools, I think teachers will have to make room for AI so that students can learn to use it appropriately and effectively as a tool, as opposed to a substitute, for learning.
enhancing critical thinking,creative problem-solving, and adaptive learning processes
I am curious as to how the authors of this study measured this--a major concern regarding AI usage is that it might prove detrimental to critical thinking skills, in particular.
Standardization of intervention
I understand these are features of the two visual aid formats, but I wonder how the color coding or, most importantly, the interactive element of the skeleton concept maps might've affected the findings. Might be useful to discuss this (if not mentioned in the limitations)
Justification for Delayed Post-Test
Interested in justification for the duration before the delayed post test. Why 3 days and not a week or more?
A week later, after wash-out
Might be useful to include a few lines justifying the wash-out period for this study specifically. What unique factors about podcasts or the included visual aids that might necessitate wash-out?
Structured feedback
Would appreciate more information about the tool and process of feedback
studentparticipants for the pilot study were drawn from a cohort not enrolled in the main study armbut matched in training level and learning environment.
Would help to mention it earlier as well
Figure 8
Well done. I love the color coding and skeleton element
3.11.1 Steps for development of instrument (Clinical scenario-based SBA-type MCQs)
Nicely done and written!
My question would be: Any reliability testing done? Especially since the study has multiple iterations- how might the presence of test-retest reliability affect your interpretation of the findings?
he purpose was to ensure thatall students began the case with a comparable baseline understanding of key conditions, therebyreducing variability in prior knowledge and increasing the reliability of post-interventionperformance measures
Good call
Figure 7
Might be helpful to include the graph at the beginning of the section as an overview and a chance to set reader expectations
small sample of participants representative of the targetpopulation
Where did the sample come from? is it from the rest of the batch (those who were not included?) or a different university?
he sessionon ‘Red eye’ and ‘sudden painless loss of vision’
Curious how these are usually taught in the curriculum
+If known, what sort of need assessment was originally done to include those topics in the curriculum?
was employed
This is mentioned in later sections, but might be helpful to state clearly if it was designed by the researcher from scratch or adapted/modified from any other source
1.3 Rationale
Adding a bit more about why the author thinks the intervention would affect CT specifically would greatly strengthen the rational
++
I'm curious, any data on the effect of audio-only podcasts (without visual aids) on critical skills?
The introduction mentions that the podcasts' potential in developing critical thinking is unexplored more than once- and a comparison between supplementing podcasts with either assumes effectiveness. Would love to see data tackling that point or at least a discussion of it
A simple random sampling technique was applied to select participants for the study
If the accessible population is 110 and the minimum target sample is 94, why did the author choose random sampling over purposive whole-population sampling?
Figure 5
Very informative graph.
-Recommend editing the position of "immediate" and "Delayed" tests as it currently appears to associate with Groups A and B
-The graph implies there's more cross over after Round two. Recommend editing it to clarify.
-Might also be used to add your washout period to the graph
-Kindly also connect Pre-test, control variable, and post-test by arrows; and unify the way "Audio podcast - clinical case discussion" is written in rounds 1 and 2
Exclusion criteria
Exclusion criteria are typically factors that may disqualify participants who are otherwise included in the study. With that in mind, what criteria might exclude any of your 4th year students from this study?
randomly divided into two groups,
Recommend to mention randomization method here or move the sentence to 3.7
Notably, their study revealed that 87% of surveyed students demonstrated a visuallearning preference, suggesting that audio-only formats may inadequately serve a largeproportion of learners. The authors proposed incorporating visual aids, such as images orinfographics in show notes to better support knowledge retention and accommodate diverselearning styles (Okonski et al., 2022)
Might strengthen the rational section if added there
gennady.bereschnoy3:35 PM@Honza Zidek 🐖 Hallo Jan, One more Question: -we have, ( for ex.! ) Meta-Infor about :::--- "minLength": 32, "maxLength": 64, "pattern": { "regex": "^[a-zA-Z0-9-]{32,64}$", :::----------------- where the values like 32, 64, rexexp is NOT 100% specified or we still not able to found confirmation what is RIGHT values. So the Q is: !! Q!! what you prefer in such case?: some real-like value like it is on example, the null-value, till we get 100% confirmation about such specification ?Honza Zidek 🐖3:42 PMThe placeholder value is always good, and it is just an example, so put it whatever you know at the moment - like a real API key copied from the web of a providerThe pattern influences the validation, so if you are not sure with the regex, do not return any pattern at all (or pattern = null, which is the same for our parser)The same for maxLength and minLength BearbeitetHonza Zidek 🐖Sorry, I meant placeholder and not exampleLeandro R. Effinger3:46 PMgreat, thanks for the answer
LEO WTF!?
My late policy and willingness to make accommodations are generous even during normal times, and if your life is being turned upside down, I’m willing to be as flexible as you need me to be—so long as you are active in communicating with me.
This is a great policy. Thank you for the flexibility.
activities, but James also relied on more objective measures, including the use of various recording devices, and examinations of concrete products of mental activities and of anatomy and physiology (Gordon,
This is an example of the development of the empirical method, where scientist start to use more objective such as the usages of examinations or recording devices. Instead of using opinion-based methods to examine mental activities, like Wundt's idea of introspection, James use functionalism to properly focus on how mental activities helped an organism fit into its environment using test and experiments.
and he believed that the goal of psychology was to identify components of consciousness and how those components combined to result in our conscious experience. Wundt used introspection (he called it “internal perception”), a process by which someone examines their own conscious experience as objectively as possible, making the human mind like any other aspect of nature that a scientist observed. He believed in the notion of voluntarism—that
Wundt's view of psychology as a study of conscious experience was the start of psychology and I find it really interesting how this one though created the formal beginning of psychology. Wundt's usage of introspection (a process by which someone examines their own conscious experience as objectively as possible) is an early and significant way for Wundt to study the human mind. However, these experiences can be totally subjective from the actual person. How can one's experience be verified by another? I thought that introspection was an unreliable way to study psychology. In addition, Wundt's belief in volunteerism (the concept in which people have free will) will slowly become a more popular idea now. Especially in the present time, many people feel as if they can choose their own path and make their own decisions, rather than their lives being prechosen for them.
So, in the East German "revision" of Cinderella, the fairy godmother has been eliminated
Learning that the fairy god mother wasn't in the story was shocking. She was such a crucial part of the American story. I've never heard of a version where she gets her glam from a tree that started from her mother's grave, and grew from Cinderella's tears. - Olivia Fink German 2254.02
Typically, a hemolytic attack starts with malaise, weakness, and abdominal or lumbar pain. Within a time frame of several hours to 2–3 days, the patient develops jaundice and often dark urine. T
sxs
G6PD is a housekeeping enzyme critical in the redox metabolism of all aerobic cells (Fig. 105-1). In red cells, its role is even more critical because it is the only source of NADPH, which directly and via GSH defends these cells against oxidative stress
highlighted
According to Joseph and Frances Gies, authors of Life in a Medieval Castle, Winter was the season from Michaelmas (September 29) to Christmas when wheat and rye were sown. From the end of the Christmas holidays to Easter was the season when spring crops were sown: oats, peas, beans, barley, and vetches. From the end of Easter week to Lammas (August 1) was summer, and from Lammas to Michaelmas was harvest, or autumn. (p. 206) This is in contrast to our modern calendar of seasons, which occur approximately as follows: Spring: March 20 Summer: June 21 Autumn: September 22 Winter: December 21
Crying shaking throwing up
1 final assignment worth 20 points
What is the final assignment going to be on?
Final Assignment & Final Reflection
What is the final assignment and reflection going to be on?
The ability to feel connected to ones haukāinga and ahikā from adistance is a difficult compromise and one that many of our whānauhave to face if they choose to live away from their tūrangawaewae orlive overseas
In the text even though Sciascia writes that "Many Māori of the diaspora are actively seeking and using virtual media to make and maintain strong connections with their haukāinga" I also believe it is difficult to maintain a genuine connection through social media without "kanohi ki te kanohi", the difficulty is that you do not get to interact on a personal level. It just allows you to feel more connected with human contact.
Capitalism has been immensely successful, on many criteria. It ushered in theindustrial era, and the prosperity (for some people, but not everyone) that camewith it. It ruthlessly undermines old-fashioned restrictions and taboos, and probesendlessly to find new ways of generating private profit (some of which are sociallyuseful, some of which are not). It harnesses immense energy, creativity, anddiscipline from many of its participants
What really caught my attention here is how Stanford points out that capitalism is both powerful and deeply flawed. It’s impressive that it’s been able to drive innovation and productivity, but also kind of scary how uneven the benefits are. If capitalism depends so much on people’s energy and creativity, what happens when more and more people feel burnt out or left behind by the very system they’re fueling?
Most people think economics is a technical, confusing, and even mysterioussubject. It’s a field best left to the experts: namely, the economists.
This is such a powerful statement because regular people are always taught that the economy is so confusing but in reality it is really not that hard but economists want to be known for having all the answers.
Some receive noincome at all: like the growing army of “interns” who now work for free, in hopes ofeventually landing a paying job.
This made me think about how normalized unpaid internships have become, especially for young people trying to enter competitive fields. Is this "hope" of a future job enough to justify free labor? What happens when that hope doesn't ever lead to a job? It feels like a way to bypass labor laws under the premise of gaining experience
The ratio of labour costs to productivityis called unit labour cost. It represents the amount that employers must paytheir workers for each unit of output they produce.Employers strive to minimize unit labour cost, and they do this by addressingboth parts of the equation: reducing wages and boosting productivity. The followingsimple formula is a convenient way to summarize the various interactions betweenworkers and employers – often conflictual, and occasionally harmonious.Unit labour cost = Compensation = CompensationProductivity Intensity * EfficiencyTo reduce unit labour costs, employers can try to cut compensation (wages andbenefits) on the top of the equation, or they can try to increase productivity onthe bottom of the equation.
This passage made me think differently about how employers really calculate the “cost” of labor—not just by paying wages, but in relation to productivity. I had never considered the term unit labor cost before, and now I see it as a key measurement that drives many decisions about wages and work intensity. Stanford points out that reducing this cost can come from either cutting wages or increasing productivity, which explains why employers might push for faster work or new efficiency measures. If productivity improvements can sometimes benefit workers, how might employers and workers negotiate to balance efficiency gains with fair compensation?
One defining feature of capitalism is that most production is undertaken togenerate private profit. (The other defining feature of capitalism is that most of thework required for production is performed in the form of wage labour.) In orderto generate and collect that profit, a specialized institutional form has emerged:the private company. Today private firms dominate the economy: their decisionsabout investment, production, and employment are the most important factorsdetermining whether and how the economy evolves, and how people work. Theactions of private companies are far more important on a day-to-day basis thanthings that governments do. This makes it incredibly ironic to hear governmentofficials claim credit for “good economic management,” or opposition leadersberate the party in power for “bad economic management.” These political debatesare mostly beside the point – since in reality it is businesses, not government, thatsit in the economic driver’s seat.
This paragraph really made me think about how much power private firms really have in shaping our day-to-day economic lives, even more so than governments. It’s interesting to consider that political debates about “bad economic management” might be kind of missing the bigger picture since businesses are driving most decisions about investment, production, and employment. An interpretive question I have is: if private companies dominate the economy in this way, what implications does that have for how we think about economic inequality and the ability of government policies to influence everyday life?
technology refers to a techniqueof production, not to a particular piece of equipment or machinery. The termis often misused to refer to equipment itself (“Wow, dude, you have someawesome technology in here!”). In its correct use, though, “technology”refers to knowledge about how to produce something – not the physical toolswe use to produce it. A new technology can be highly productive; but a toolor machine, in and of itself, is not.
This really made me rethink how I’d been using the word “technology.” I used to think that having the latest machines or gadgets automatically counted as new technology, but Stanford points out that it’s actually about knowledge of how to produce something. Understanding this distinction is a good insight moving forward because it shifts the focus from just owning tools to figuring out better ways to use them to be more productive/effective.
economic growth is usually measured by the expansion of real GDP.Economic growth usually consists of two components: an increase in the amountof work that is performed, and improvements in efficiency or productivity(that is, increases in the amount of output produced by each hour of that work)
I’m curious about the real-world consequences of measuring growth this way. Does focusing on real GDP hide inequality, since aggregate growth doesn’t show how wealth is distributed?
Profit represented anew, more subtle form of exploitation: an indirect, effective way of capturingeconomic surplus from those (the workers) who truly do the work. Marx tried(unsuccessfully) to explain how money prices in capitalism (which include thepayment of profit) could still be based on the true underlying “labour values” ofdifferent commodities. And he predicted the ultimate breakdown of capitalism,in the face of both economic instability (the ongoing boom-and-bust cycle) andpolitical revolution. Marx’s ideas were very influential in the later development oflabour and socialist movements around the world.
This passage now has me thinking about the idea of profit as a “subtle form of exploitation”. I never thought of it this way but it really is so true. I wonder about the implications of this for modern labor markets, especially with gig work or precarious jobs where workers often have little bargaining power. Also, it’s interesting that Marx predicted capitalism’s breakdown due to both economic instability and political factors.
Nothing better exemplifies economists’ know-it-all attitude than debates overfree trade. Conventionally trained economists take it as a proven fact that free tradebetween two countries always makes both sides better off. People who questionor oppose free trade – trade unionists, social activists, nationalists – must eitherbe acting from ignorance, or else are pursuing some narrow vested interest thatconflicts with the broader good. These troublesome people should be lectured to(and economists love nothing better than expounding their beautiful theory ofcomparative advantage*), or simply ignored
Stanford is saying economists defend free trade almost like a faith... I think he’s pointing out that their belief doesn’t always match real-life outcomes.
If they see it as fact, how do they respond when workers get hurt by free trade?
With the rise of the inclusion of Aboriginal artists in institutionalarts programming in the past twenty years, there has been in-creased dialogue around the nature and political/cultural impera-tive of Aboriginal arts presentation and discourse.
With the inclusion of Aboriginal artists I also think that these creations have led to discussions about respectful, authentic representation to promote understanding, sovereignty, and reconciliation. I think it is important for the aboriginal people to be able to express themselves through the lenses of their eyes and what they genuinely went through much rather than someone who just read a story or two.
Description
A comprehensive guide for content creators on Oneup Hive. Using the Cartel Post Framework to enhance the design and structure of articles. With Markdown and PeakD Snippets. Learn essential elements like effective headings and visual integration. See the use of tables to create engaging and visually appealing posts.
Description
Who invented the lighthouse? Learn the history and evolution of lighthouses and tilting beacons in navigation. See their literary and cultural symbolism.
Instead, skip around using the table of contents to find answers to your questions or to do exercises that will improve your reading and writing skills.
It is nice that we can pick out certain things we need to know about writing in this book. Instead of having too read everything to understand writing.
if he loses possession he loses contact with the world. ... He loves control, and in the act of controlling he kills life.
Control is hard to not crave in the classroom as educators are programmed to "control" their students behaviors and learning. Yet, control suppresses creativity, so with this we must begin to take a different approach.
To achieve this, they must be partners of the students in their relations with them.
Traditional teaching does not encourage this, but as I have seen in the classroom, the more you are working alongside the students rather than dumping information and expecting them to understand and demonstrate understanding based on the belief that we must "fill" them with specific knowledge prior to testing, students thrive and their creativity and individualism begins to flourish.
It is not surprising that the banking concept of education regards men as adaptable, manageable beings. The more students work at storing the deposits entrusted to them, the less they develop the critical consciousness which would result from their intervention in the world as transformers of that world. The more completely they accept the passive role imposed on them, the more they tend simply to adapt to the world as it is and to the fragmented view of reality deposited in them.
Friere speaks truth here. Education crosses its fingers and hopes that students will be complacent and simply follow the rules they are given. They want them to be vessels for their own words, as teachers are the deliverymen and the students are the recipients. Oh, and if they went against the role given to them and decided to not be passive? Then they are viewed as outsiders, going against the so-called "social norms".
The oppressors use their "humanitarianism" to preserve a profitable situation.
I found this statement to be so true within my own experience in education. Those who are enforcing this banking concept of education are the ones who claim they know what is best for the kids. Yet, many of us in education can see right through this facade and understand it for what it truly is; greed.
the teacher acts and the students have the illusion of acting through the action of the teacher;
Students can reenact teacher behavior (simply copying), and those who make the big decisions in education would be jumping up and down, yelling, "Yes! Great job! You are learning!". Copying and learning are not the same, yet this form of "educating" is highly celebrated.
Narration (with the teacher as narrator) leads the students to memorize mechanically the narrated content. Worse yet, it turns them into "containers," into "receptacles" to be "filled" by the teacher.
Unfortunately, I feel this way sometimes with my elementary students. The curriculum can be horribly boring, but we must teach it as it is what is "designed to work", (just to be clear- I am currently rolling my eyes at that statement). We unload all of this content on them to ensure they are "filled" enough to be able to prove their competence during a state test that was probably created by someone who has never stepped foot in the classroom.
The outstanding characteristic of this narrative education, then, is the sonority of words, not their transforming power. "Four times four is sixteen; the capital of Para is Belem."
These words are just that, words. Students cannot put meaning behind it if they are not given a way to actually CARE about the content, rather than just be listening to someone speak AT them.
The teacher talks about reality as if it were motionless, static, compartmentalized, and predictable. Or else he expounds on a topic completely alien to the existential experience of the students. His task is to "fill" the students with the contents of his narration— contents which are detached from reality, disconnected from the totality that engendered them and could give them significance. Words are emptied of their concreteness and become a hollow, alienated, and alienating verbosity.
Often, teaching is done through the curriculum given to through companies whom profit off of the education of students. The curriculum is based on standards that must be met in order to successfully meet the goal of the grade level or year for that student. Yet, the teachings can be so dry (literally drier than the Sahara Desert), to the point where students often find themselves in a process of "hearing" the words, but not truly developing a conceptual understanding. This is often due to the lifelessness of the words, they have no meaning other than "You must know this!", to the students.
Review coordinated by Life Science Editors Foundation Reviewed by: Dr. Angela Andersen, Life Science Editors Foundation Potential Conflicts of Interest: None
PUNCHLINE This preprint uncovers how embryonic oxygen levels act as a regulatory switch controlling limb development timing in mammals. Using mouse and chick embryos, the authors demonstrate that hindlimb initiation in mammals is delayed due to hypoxia-induced expression of NFKB transcription factors (cRel, Rela) and Hif1a, which repress the limb-initiating gene Tbx4. In contrast, chick embryos in normoxia activate fore- and hindlimbs simultaneously. This oxygen-dependent repression is lifted as placental oxygenation increases, triggering hindlimb EMT and Tbx4 expression. Notably, limb heterochrony is not due to cis-regulatory evolution, but instead arises from differential trans-acting factor expression. The findings reframe heterochrony as an environmentally cued developmental program in placental mammals.
BACKGROUND Heterochrony—alteration in developmental timing—has long been recognized in limb evolution. While birds initiate fore- and hindlimb development simultaneously, mammals typically exhibit delayed hindlimb formation. This developmental delay has been hypothesized to reflect an "energy trade-off" during early embryogenesis. Yet, the molecular mechanisms linking the environment to timing remain unexplored. Zhu et al. provide the first mechanistic insight by identifying oxygen levels and NFKB signaling as modulators of limb timing in mammals.
KEY QUESTION ADDRESSED What molecular and environmental factors underlie the delay in hindlimb development in mammalian embryos compared to avian species?
SUMMARY Using mouse and chick embryos, the authors first demonstrate that mammalian hindlimb development is delayed starting from the earliest stage of limb bud formation—specifically, the epithelial-to-mesenchymal transition (EMT). This delay correlates with delayed expression of the hindlimb-specifying transcription factor Tbx4, but not its upstream activators (Pitx1, Isl1) or its forelimb counterpart (Tbx5). Surprisingly, enhancer-swap experiments rule out differences in Tbx4 cis-regulatory elements as the cause. Instead, bulk RNA-seq and functional screens reveal cRel, a member of the NFKB family, as a repressor of Tbx4 in early mouse hindlimb buds. Further experiments show that cRel and Rela are upregulated by hypoxia, and their expression is suppressed as the embryo transitions to normoxia via placental oxygenation. Culturing mouse embryos in normoxic conditions prematurely induces Tbx4 expression and EMT in the hindlimb. Knockout and overexpression experiments with cRel, Rela, and Hif1a confirm a hypoxia–NFKB–Hif1a–Tbx4 regulatory axis. This mechanism links maternal oxygen levels to developmental timing and may be an adaptive feature of viviparous mammals.
KEY RESULTS Hindlimb EMT and Tbx4 expression are delayed in mice but not chicks * → In mouse embryos, hindlimb EMT is delayed by ~18 hours relative to the forelimb (Figure 1A–B) * → In chick embryos, forelimb and hindlimb EMT occur nearly simultaneously * → Expression of Tbx4 (hindlimb) and Tbx5 (forelimb) correlates with EMT timing in both mouse and chick embryos (Figure 1C–I)
Early limb patterning signals are not delayed (mouse and chick) * → BMP, Wnt, and RA signaling are active in both forelimb and hindlimb fields in mouse and chick embryos at the same developmental stage (Figure 2A–B) * → Expression of upstream transcription factors Pitx1, Isl1, and Hoxb9 occurs on time in both limb fields in mouse and chick embryos (Figure 2C–F)
Tbx4 enhancer function is conserved across species * → The mouse HLEA/HLEB and chick Tbx4-Rec1 enhancers drive equivalent spatial and temporal expression when introduced into either mouse or chick embryos (Figure 3C–E, H) * → CRISPR/dCas9-KRAB repression of Tbx4-Rec1 in chick embryos reduces Tbx4 expression (Figure 3F–I) * cRel and Rela repress Tbx4 in mouse hindlimbs * → Bulk RNA-seq of early hindlimb buds from mouse embryos reveals cRel as a candidate repressor of Tbx4 (Figure 4A–C) * → Electroporation of cRel and Rela into chick hindlimb buds reduces Tbx4 expression and limb bud size (Figure 4D) * → In cRel knockout mouse embryos, Tbx4 expression is elevated and EMT occurs earlier than in controls (Figure 4E–H)
Oxygen regulates hindlimb timing in mouse embryos * → In mouse embryos, early hypoxia is evidenced by nuclear Hif1a accumulation in hindlimb mesenchyme (Figure 5A–C) * → Culturing mouse embryos under normoxic conditions leads to precocious Tbx4 and Pitx1 expression in hindlimbs (Figure 5E–G) * → EMT is also accelerated under normoxia in mouse hindlimbs (Figure 5H–I) * → qPCR on lateral plate mesoderm (LPM)-derived cells from mouse embryos shows cRel is upregulated in hypoxic vs. normoxic conditions (Figure 5J)
cRel and Hif1a functionally interact in mouse embryos * → In Hif1a knockout mouse embryos, Tbx4 expression is elevated and hindlimb EMT is precocious—mimicking the cRel knockout phenotype (Figure S9I–J) * → Manipulating cRel expression alters Hif1a levels in mouse embryonic cells (Figure S10) * → scRNA-seq from mouse LPM derivatives confirms upregulation of Tbx4, Pitx1, and Hox9 under normoxia (Figure S6E)
STRENGTHS * Identifies a molecular mechanism linking environmental oxygen levels to developmental timing * Demonstrates that heterochrony arises from trans-acting regulatory inputs, not enhancer evolution * Uses a broad and rigorous toolkit: enhancer reporters, genetic knockouts, hypoxia assays, ex utero culture, single-cell and bulk RNA-seq * Highlights the adaptability of developmental programs to viviparous life history * Conceptually reframes heterochrony as plastic and environmentally modulated
FUTURE WORK & EXPERIMENTAL DIRECTIONS * Characterize direct chromatin binding of cRel and Hif1a at Tbx4 enhancers * Examine other NFKB targets in the LPM that might contribute to limb timing * Explore whether similar timing mechanisms are conserved in other mammalian species, including humans * Investigate how oxygen levels interface with metabolic and mitochondrial signaling during early development * Test whether early normoxia affects other embryonic heterochronies beyond limb formation * Directly test whether hypoxia modulates limb timing in birds. Although oxygen manipulation in chick embryos is technically challenging, comparative data would clarify whether the hypoxia–NFKB–Tbx4 axis is a placental adaptation or part of a broader vertebrate timing program.
AUTHORSHIP NOTE This review was drafted with the assistance of ChatGPT (OpenAI) to organize and articulate key insights. Dr. Angela Andersen checked the final document.
FINAL TAKEAWAY This preprint provides a paradigm shift in our understanding of limb heterochrony by uncovering a mechanism through which maternal oxygen availability regulates the timing of hindlimb development. By linking environmental hypoxia to NFKB- and Hif1a-mediated repression of Tbx4, the authors show how the embryo delays hindlimb formation until placental oxygenation is sufficient. This elegant mechanism offers an evolutionary and physiological explanation for mouse hindlimb delay, and it opens new avenues in developmental timing, maternal-fetal signaling, and the evolution of viviparity.
The Lieber Code of 1863, the Union Army and President Abraham Lincoln’s laudable, if admittedly naïve, attempt to limit the ravages of the American Civil War, precipitated a paradigm shift away from the mere moral condemnation of the destruction and appropriation of cultural property toward express legal proscription. Article 35 of the code is unambiguous: “Classical works of art, libraries, scientific collections, or precious instruments . . . must be secured against all avoidable injury, even when they are contained in fortified places whilst besieged or bombarded.” The prescriptive, deterrent objective of the code is reflected in Article 44, which makes clear that the intent was not only to prohibit such conduct, but to actively ascribe a penal basis for individual responsibility.2
Lieber Code of 1863 (U.S. Civil War: first documented sanctions against intentional destruction of heritgae)
Ahmad al-Faqi al-Mahdi
member of Ansar Dine, a Tuareg Islamist militia in North Africa. Al-Mahdi admitted guilt in the International Criminal Court in 2016 for the war crime of attacking religious and historical buildings in the Malian city of Timbuktu (Wikipedia)
Nuremberg and then later at the International Criminal Tribunal for the former Yugoslavia
war crimes
prehistory of individual criminal responsibility for heritage destruction as an international crime, looking at the oft-neglected efforts undertaken in the aftermath of World War I and World War II
destruction of art by Nazis; connection to degenerate art?
securing individual criminal accountability for the deliberate destruction of cultural heritage, whether inside or outside the context of armed conflict
consequences for destruction of material cultural heritage
The cells convert excess glucose to an insoluble substance called glycogen to prevent it from interfering with cellular metabolism. Because this ultimately lowers blood glucose levels, insulin is secreted to prevent hyperglycemia (high blood sugar levels)
This sentence is logically backwards and misleading.
What It Should Say: "After eating, when blood glucose rises, insulin is secreted. Insulin promotes the uptake of glucose by cells and its conversion into glycogen for storage. This process helps lower high blood glucose levels, thereby preventing hyperglycemia."
The way this is phrased in English implies that long-periods of fasting increases your blood sugar (from what food source?), and then insulin is secreted to prevent hyperglycemia (again, from what food source?). It also implies that glucose cellular uptake somehow increases blood glucose. I read this multiple times before realising that it wasn't my comprehension which was wrong, it is just worded poorly.
It was funny if you looked at it right quick, but it got pitiful if you thought about it awhile. It was like somebody snatched off part of a woman’s clothes while she wasn’t looking and the streets were crowded.
Use of rhetorical device, public humiliation
This was the first time it happened, but after a while it got so common she ceased to be surprised. It was like a drug. In a way it was good because it reconciled her to things. She got so she received all things with the stolidness of the earth which soaks up urine and perfume with the same indifference.
Janie becomes so depressed that she succumbs to disassociating as a way to get away from reality like the purpose of drugs. Final sentence means that she lacked emotion so much that it didn't matter whether it was good or bad
“Maybe he ain’t nothin’,” she cautioned herself, “but he is something in my mouth. He’s got tuh be else Ah ain’t got nothin’ tuh live for. Ah’ll lie and say he is. If Ah don’t, life won’t be nothin’ but uh store and uh house.”
She wanted to believe that Jody was still something to/for her even though she knows deep down she's harboring hatred towards him, that's the type of character she is
powerfully
General
How early does the post arrive?
the
What makes a good story?
of the
Why do people brush their teeth before bed?
Twitter: * Leroy & The Girlfriend
TJAG ("The
Are oceans really that deep?
owned
Where are the best chips made?
Legal
Is Bluey the only thing kids watch these days?
as the
Why do pies have puff pastry?
he serves
Where is the best hot chocolate served?
As of 2023,
Why do wolves howl at the moon?
of the
Why do we always tell stories before bed?
executive
Can you get the loudest burp from eating at McDonald's?
officer
Have puppets always been the stars of sci-fi series on telly?
proposed
Your love being the only present I'd have
was
Playing gentle games in our room which holds the nest
origin
Our home being the cradle of gentleness
word's
Listening to the sounds of the country outside
of the
Living a happy life under one roof
But
Being the baby of the household
"South
Singing softly about the stars before we go to sleep
The
Dreaming of running in the fields
division
You gently singing about the branches of an oak tree to help me sleep
the
Pretending our nest is a tropical island
appeared
Seeing the magic in a small place
first
Reminiscing on the 2000's in the evening
(路南县). The
Snuggling close to your body
as Lunan County
Sharing tea, cake and jam under the covers
and
Splashing about in the bathroom sink
is the
Touching hands gently before bed
south.
Sleeping in the warm sunshine
to the
Knowing every time is bedtime
and
Answering the softest, gentlest questions
to the
Being more than just mother and daughter, just friends
to the
Reading bedtime stories every night
Luliang County
Having quiet moments like it's the '90s
the
Watching the stars outside our window
It borders
Squeezing the juice of an orange over my skin
capital
Being safe in the bedroom and the bathroom
the
Sharing weak morning snuggles
of Kunming,
Watching water flow from the bath tap like a river
jurisdiction
Knowing the only skills we have right now include weakness, courage, love and vulnerability
the
Snuggling into our cosy nest together
In practice, we can remove predicted bounding boxes with lower confidence even before performing non-maximum suppression, thereby reducing computation in this algorithm. We may also post-process the output of non-maximum suppression, for example, by only keeping results with higher confidence in the final output.
pre and post process
Janie noted that while he didn’t talk the mule himself, he sat and laughed at it. Laughed his big heh, heh laugh too.
Meaning he was sincerely laughing. Maybe a part of him did want to be a part of them but his ego and sense of duty forbade him not to which is why he looks down on others who don't have that sense as well.
The Jackson Laboratory; #023837
DOI: 10.1038/s41531-025-01084-y
Resource: RRID:IMSR_JAX:023837
Curator: @dhovakimyan1
SciCrunch record: RRID:IMSR_JAX:023837
The Jackson LaboratoryStrain #: 013062
DOI: 10.1016/j.xcrm.2025.102321
Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
Curator: @areedewitt04
SciCrunch record: RRID:IMSR_JAX:013062
The Jackson LaboratoryStrain #: 005557
DOI: 10.1016/j.xcrm.2025.102321
Resource: (IMSR Cat# JAX_005557,RRID:IMSR_JAX:005557)
Curator: @areedewitt04
SciCrunch record: RRID:IMSR_JAX:005557
Use the button to toggle highlight visibility on a pag
mnbn,n
times
Ignoring what the clock tells you and sleeping in
Iran
The freedom of a stallion
Mojtaba Maleki (Persian: مجتبی ملکی; born 1983) is an
Classic shows to cuddle up to: The Littlest Hobo, Thunderbirds, Stingray, Lassie, The Famous Five, Noddy's Toyland Adventures, Brambly Hedge, The Little Grey Rabbit, Kipper, Fireball XL5, Postman Pat
choosing a different problem from the rest of the community can lead you to explore different ideas.
how different here exactly?
Goals also make it possible for a team of researchers to work together and attack different aspects of the problem, whereas idea-driven research is most effectively carried out by “teams” of 1-2 people.
why??
On the other hand, with goal-driven research, your goal will give you a perspective that’s differentiated from the rest of the community. It will lead you to ask questions that no one else is asking,
why??
To make breakthroughs with idea-driven research, you need to develop an exceptionally deep understanding of your subject, and a perspective that diverges from the rest of the community—some can do it, but it’s difficult.
why??
you test a variety of existing methods from the literature, and then you develop your own methods that improve on them
(1) Which existing methods to test? (2) Why we have to test them before we build our own methods? What does it mean by "improve on them"?
I’ll take goal-driven research to mean that your goal is more specific than your whole subfield’s goal, and it’s more like make X work for the first time than make X work better.
what does this mean? "your goal is more specific than your whole subfield's goal" how does that align with "make X work for the first time than make X work better"?
Follow some sector of the literature.
what does this mean exactly?
Study 1 established a causal relationship between employees’ AI awareness and its dual outcomes, while Study 2 extended this relationship by controlling for traditional technology effects. The results showed that higher AI awareness among employees positively influences their work engagement through improved recovery levels. AI interventions in hotels relieve frontline staff from repetitive tasks, conserving both physical and psychological energy for more impactful responsibilities (Jia et al., 2024; Qiu et al., 2022). However, heightened AI awareness exacerbates feelings of job insecurity among employees, prompting them to engage in AI boycott behaviors. As AI increasingly replaces critical tasks traditionally performed by employees, perceived job insecurity drives behavioral responses such as boycotts, consistent with Yam et al. (2022) but inconsistent with Yam et al. (2023); Li et al. (2019), and passive responses such as burnout, workplace incivility and turnover. The findings show that employees could resort to proactive responses such as boycotts that weaken AI. Moreover, the requirement for innovativeness consumes employees’ resources (Yuan and Woodman, 2010). In a state of scarcity, employees are more likely to engage in resource-protection behaviors (Hobfoll et al., 2018). Therefore, innovativeness as a job requirement serves as a conditional variable that can strengthen the two positive relationships between AI awareness and either work engagement or AI boycott.
Study 1 and 2's results explanation
As AI replaces many hotel jobs, the remaining human roles become more competitive, retaining employees who meet their heightened expectations (Prentice et al., 2020). As AI replaces jobs in the hotel industry, the talent market tends to become saturated. With fewer job opportunities available, leaders gain greater bargaining power and employees may have less influence over their compensation, potentially leading to salary reductions.
Explains how the integration of AI is increasing industry competition, making it more difficult for people to secure jobs
To reflect this differentiation, Hellgren et al. (1999) further divide job insecurity into quantitative and qualitative forms. The quantitative form refers to the fear of losing one’s current job while the qualitative form relates to perceptions of diminished job quality and changes in the employment relationship. This distinction is the focus of many previous studies on job insecurity.
Quantitative vs. Qualitative
Currently, research on AI awareness is still in its early stages. Only a few studies have examined employees’ emotional (emotional exhaustion), psychological (job insecurity), motivational (intrinsic motivation) and behavioral reactions (work engagement and innovative behavior) to AI at the individual level (Liang et al., 2022; Koo et al., 2021; Yam et al., 2023).
There is limited research on employees reactions to AI so far
The increasing prevalence of AI technologies, e.g. machines, robots and algorithms, in the workplace signals that they may potentially replace the employees’ roles in the future, resulting in a perceived sense of job uncertainty
Highlights the risk of the industry being dominated by robots
For this reason, frontline employees should innovatively interact with AI to maintain a balance between human value and AI functionality
Mentions the importance of keeping a balance of AI and human value
Some scholars argue that the risk of being replaced by robots leads to job insecurity and maladaptive behaviors (Yam et al., 2023). For example, Koo et al. (2021) found that job insecurity among hotel employees likely detracts from their work engagement, limits their career capabilities and contributes to higher levels of job burnout (Kong et al., 2021).
Identifies the causes of job insecurity
but it presents challenges to organizational management, particularly regarding employees’ adaptive behaviors and responses. For example, hotel employees may damage AI systems due to the repetitive nature of hotel tasks and the fear that intelligent machines will replace them through automation (Raisch and Krakowski, 2021).
Mentions the challenges
In hotel operations, AI enhances employees’ productivity and efficiency to alleviate workloads
Mentions the positives of AI
This study uses a structural equation model, ordinary least squares and bootstrapping method to analyze the data collected with a field study and a scenario experiment from star-hotels in Shanghai, Paris and Seoul.
Methodology
This means you need to have it done and turned in before the start of class
That is so important to know!
This special issue explores the potential of automation, artificial intelligence, robotics and advanced data analytics in mitigating staff shortages. Automation streamlines operations, AI enhances customer interactions, robotics reimagines service delivery and data analytics informs strategic decisions. The study addresses a strategic question by combining literature reviews, data analysis, expert insights from practitioners and practical solution recommendations.
Methodology
While the potential benefits of technological developments are substantial, successful integration into the workforce requires careful consideration and planning. It is essential for businesses to strike a balance between leveraging technology and maintaining a human touch in service delivery. The effective use of technology should complement, rather than replace, human interaction, ensuring that guests continue to receive personalized and high-quality experiences (Brown and Green, 2023).
This is where my argument comes in. AI is taking over the industry, leading to job displacement and diminishing the human interaction that defines the essence of hospitality.
Robotic technology is another area where innovation is making a significant impact. Robots are increasingly being used in various roles within the hospitality and tourism sectors, from room service delivery to cleaning and maintenance. For instance, robots designed to deliver amenities to guest rooms can reduce the need for human staff to perform these tasks, allowing them to focus on more customer-centric activities (Jones, 2023). Similarly, robotic cleaners can maintain cleanliness and hygiene in public areas with minimal human supervision, contributing to overall operational efficiency.
Explains how assigning more physically demanding or hectic tasks to robots enables human employees to focus on customer-centric roles, therefore increasing the potential for improved customer satisfaction
This issue has been notably intensified by the COVID-19 pandemic, which triggered widespread layoffs, heightened job uncertainty, and altered workforce dynamics across the globe (Smith, 2023). As these sectors are heavily reliant on human interaction and personalized service, the reduction in available labor has had profound implications for operational efficiency and customer satisfaction.
The pandemic was noted as a key turning point when labor shortages began to rise, and it continues to be one of the main contributing factors to the issue.
However, successful integration of technology requires careful planning, training and ongoing maintenance to ensure a balance between technology and human interaction. By embracing these technologies, businesses can better cope with staffing deficits and position themselves for long-term success in a rapidly evolving environment.
Suggests a good balance of both technology use and human interaction to maintain the spirit of hospitality
utomation streamlines operations, AI enhances customer interactions, robotics reimagines service delivery and data analytics informs strategic decisions.
Highlights the benefits and positive impacts of AI implementation
the brain, along with the rest of life, was created by a non-material source or divine being and that therefore the mind has divine origins
I understand and am interested in the way our bodies and brains work biologically, but my personal beliefs definitely align with this, I am sure spirituality has a lot to do with the potential we have mentally and physically.
Federal agencies play a significant role in business operations. When Pfizer wants to bring a new medication for heart disease to market, it must follow the procedures set by the Food and Drug Administration for testing and clinical trials and secure FDA approval. Before issuing stock, Pfizer must register the securities with the Securities and Exchange Commission. The Federal Trade Commission will penalize Pfizer if its advertisements promoting the drug’s benefits are misleading. These are just a few ways the political and legal environment affect business decisions.
Do you believe that government regulations more often aid in the growth of businesses or hinder them with restrictions, even though they can occasionally create opportunities (such as the Telecommunications Act of 1996 increasing competition)?
Government is our largest and most pervasive not-for-profit group. In addition, more than 1.5 million nongovernmental not-for-profit entities operate in the United States today and contribute more than $900 billion annually to the U.S. economy.3
The fact that nonprofit organizations make over $900 billion in annual contributions to the US economy intrigued me. That demonstrates that they have a significant financial impact in addition to helping people socially, much like traditional businesses.
A business is an organization that strives for a profit by providing goods and services desired by its customers.
I liked this sentence a lot as it sums up what a business means. People get mad about how some business operate but at the end of the day they're more often then not just giving the majority of people what they want.
Entrepreneurs are the people who combine the inputs of natural resources, labor, and capital to produce goods or services with the intention of making a profit or accomplishing a not-for-profit goal.
Its interesting how entrepreneurs have emerged in the business world. The definition for an entrepreneur is different from the way many describe and present themselves in current times especially with social media. The business world definition is very different and I find it interesting how business has so much room for many different represented business people.
finding time for both family and work can be difficult,
I studied abroad in Spain last semester and found it pretty shocking to see how different their work to life balance is. I spoke to a couple of professors about this and they all said it's because they believe that your life shouldn't revolve around work and they really prioritize personal connections.
A company whose costs are greater than revenues shows a loss.
I find it very interesting that when businesses first start it's pretty normal for costs to be greater than revenue because of how much investing goes into a starting a new company.
Ultimately, our approach is based on our beliefs about how students learn.
I wonder how much our beliefs affect our teaching approach. I know that as I have learned more and more about the art of teaching, my teaching approach has changed over time. However, it is definitely still rooted in the values I discovered as a kid, which makes me wonder once more if each generation of teachers are influenced by the generation of teachers' before them at a much deeper level than expected.
Ultimately, students are best served when all three variations—Arts as Curriculum, Arts-Enhanced Curriculum, and Arts-Integrated Curriculum—are part of their education.
I think that this was really interesting because we see this same theme prevalent in almost all of our teaching strategies. The more ways we can use to engage our students, the easier it is for our students to remember the information we give them.
For example, students meet objectives in theater (characterization, stage composition, action, expression) and in social studies.
I'm a theatre arts education major and I wish theatre was done more in the classrooms. Thinking back to when I was in elementary school, we rarely did anything with theatre. It was mostly art and music, which is great but I wish theatre was more included because it is so important.
All three variations are important, needed, and valid. All benefit from being supported by arts experiences—where students attend performances and exhibits by professional artists to engage in authentic experiences that deepen and broaden their arts understandings.
Experiencing and seeing the arts is so important because students get to see a real life example and it can help with their understanding, but it's something that they can enjoy and be inspired by
Group Work
Often times in group work, Allow other to take a lead. but in some cases ill rally the other on a concept that would make a boring project enticing to less than motivated members to complete some work.
Download the complete Review Process [PDF] including:
Before you read the following essay, think about its title, the biographi-cal and rhetorical information in the headnote, and the writing prompt
Doing this can make you think of questions to ask yourself before you read. It can answer the questions you think of and give yourself a better understanding and clear up any unknown information
What does the writer want to say? What is the writer’s main point or thesis?2. Why does the writer want to make this point? What is the writer’s purpose?3. What pattern or patterns of development does the writer use?4. How does the writer’s pattern of development suit his or her sub-ject and purpose?5. What, if anything, is noteworthy about the writer’s use of this pattern?6. How effective is the essay? Does the writer make his or her points clearly?Asks ques-tion central to the essay and relates army expe-rienceRosa_52017_03_Ch02_043-078.indd 49Rosa_52017_03_Ch02_043-078.indd 4911/18/11 12:11 PM11/18/11 12:11 PM
I beleive if you ask this to yourself while reading, it will help you understand more about what you are actually reading and you may be able to look more into and understand the reading better than if you are not using these questions.
hat’s the essay about? What do you know about the writer’s background and reputation? Where was the essay first published? Who was the intended audience for the essay? How much do you already know about the subject of the reading selection?
This is extremely important when considering what you are going to write about and how you are going to write it. I definitely need to work on understanding contexts more before diving into an essay or article. Thank you for this information.
With the first reading, you want to get an overall sense of what the writer is saying, keeping in mind the essay’s title and the facts that you know about the writer from the essay’s head-note
Personally, I don't necessarily agree with this take--I think your first read-through of any article or essay should be a full analysis and your second read-through should focus on the nuances you missed... the reason for this is because a 'lazy read-through' is not as efficient.
Similarly, most of us do not ask our-selves why one piece of writing is more convincing than another.
I think this is a very interesting topic because as a writer you definitely are comparing your work to others but as a reader--the comparison dilemma does not happen as frequently.
Always read the selection at least twice, no matter how long it is
I totally agree with this. It can be annoying when it is a long text but it's always worth it. Especially if the text is super dense, sometimes you can get lost in the wordiness and lose the actual meaning within it.
Jot down whatever marginal notes come to mind.
When annotating, I have found that writing whatever comes to mind is actually more helpful than having more structured/formal annotations. The informal annotation still gets the point across and it is in your own words, so it might make more sense to you when reading it back than something more formal.
Active reading is a skill that takes time to acquire.
I mentioned earlier, but many students are not participating in active learning. That being said, it is not necessarily their fault. Active learning is a learned skill and takes focus and time. Some students don't realize that there is a distinction between reading and actively absorbing the material. I think this skill should be taught more, especially to new students.
Late work may be accepted with a request for extension which was submitted up to 48 hours before the due date.
Having a professor who is flexible with their grading and times and dates for assignments is very helpful and makes life a lot less stressful for us students.
As long as work has been submitted that fulfills all of the requirements of the assignment, work will receive at least a B grade. Work which demonstrates higher quality and/or demonstrates risk-taking in considering or implementing new ideas will be awarded an A
There is a lot of time in different classes that things come up and some assignments are not able to be completed on time and the professor will dock points. It is good to know a good grade can still be received even if it is later, especially if we work hard on the certain assignment.
Personal NarrativeLength: Approximately 1000 words (4 double-spaced pages)
I like how the first big writing assignment is a personal narrative. This is a great way of getting us students to open up slowly and what is the easiest topic to write about when you're new to writing? Yourself!
All assignments for this course must be written and submitted directly in Google Docs.
A very interesting take is displayed here. I use Google Docs religiously so that makes me very happy to hear but having an actual assignment be submitted through the platform is new to me. I personally hope that other students can get comfortable with this method quickly.
As long as work has been submitted that fulfills all of the requirements of the assignment, work will receive at least a B grade. Work which demonstrates higher quality and/or demonstrates risk-taking in considering or implementing new ideas will be awarded an A.
A very generous rule and statement from our professor here. I wish more writing classes considered this point of view more. Many people taking English classes in college are either newer to the language or are not as comfortable with writing. I hope more professors follow in your footsteps.
In this course I need you to be brave. You will read things that may make you uncomfortable. You will discuss difficult topics. This will stretch the boundaries of what you may think you are capable of to new levels.
Thank you for being transparent with us and setting the tone for this class clear from the start. I hope that my fellows peers and I can work on opening up our personal lives at a professional and comfortable level in this class.
This is meant to ease the worry over grading for you! As long as you sincerely attempt the assignment you will get at least a B and may likely get an A depending on your work.
I think that effort is really important and I like that in this course if you show effort, it will pay off!
Late work may be accepted with a request for extension which was submitted up to 48 hours before the due date.
This is super helpful in case of an emergency, I like that there are policies in place for it so we as students know what to look out for.
practice these new skills without worrying about being penalized by a low grade.
I am excited for this because it gives students creative freedom to try certain techniques without the fear of getting a bad grade!
f how all your assignments should be submitted
I appreciate how clear the guidelines are and it is nice that every one of these assignments will follow this outline, so we can know what to expect!
with people in different parts of the world not only making the same basic discoveries but making them pretty much simultaneously.
I find it interesting how all sorts of different civilizations everywhere around the world were evolving at close to the same pace without even being in contact with each other at the time.
Over generations, women (who were the farmers in ancient Mexico) selectively bred the grass to produce more and bigger seeds. Maize is currently the most important staple in the world for both human and animal feed, as well as in industrial uses like High Fructose Corn Syrup, plastics and fuel.
I find it interesting how people found out how to breed something that was grass and end up turning it into something as poplar as corn.
t David Autor, Lawrence Katz and Alan Krueger examined. In their 1997 article, they argued that the rapid spread of computer technology in the workplace may explain as much as 30 to 50 percent of the increase in the growth rate of demand for more-skilled workers since 1970. The three economists found that the demand for college-level workers grew more rapidly on average from 1970 to 1995 than from 1940 to 1970. This increased demand was initially met with a sufficient supply of college-educated workers. That supply slowed at the beginning of the 1980s, however, eventually causing a shortage that led to a widening of the wage gap between those with and without college degrees. An even more striking finding by the authors was that industries displaying the largest increases in skill requirements—legal services, advertising and public administration, for example—were the biggest users of computers. 6 Relative to other industries, these have exhibited greater growth in employee computer use and more capital investment in computers both per worker and as a share of total investment. In addition, these high computer-use sectors appear to have reorganized their workplaces in a manner that disproportionately employs more educated—and higher paid—workers.
rossum’s universal
Urbanization accompanies specialization. People in cit-ies need to trade for food, meaning that the urban dwell-ers must provide goods and services useful for farmers.Urbanization promotes complexity. The more denselypeople are packed, the greater the degree of special-ization that can be accomplished. The historical trendis toward more specialization, more trade, and moreurbanization
I never thought about the fact that urbanization accompanies specialization. But it does make sense that the more specialized the world became, it allowed the world to become more urbanized.
At times, intermediaries may enjoymore trust than they deserve, enabling them to finance anunsustainable boom. Once the fragility of the intermediariesis exposed, the level of trust falls, and there can be significantadverse consequences for economic activity
This makes me wonder if trust is so central to financial intermediation, what mechanisms best prevent crises caused by overconfidence, and how do these interact with the complexity of modern specialization?
Entrepreneurs constantly test new typesof specialization, leading to what Joseph Schumpeter calledcreative destruction, meaning new enterprises that drive oldfirms out of business. Modern production processes involvemany layers and many steps, making the patterns of specializa-tion highly complex.
This section shows how specialization is dynamic, not static. It made me reconsider my assumption that gains in efficiency are permanent; instead, they are constantly challenged by innovation. It also highlights the tension between stability and change in modern economies.
But if they had allwrought separately and independently, and withoutany of them having been educated to this peculiarbusiness, they certainly could not each of them havemade twenty, perhaps not one pin in a day; that is,certainly, not the two hundred and fortieth, perhapsnot the four thousand eight hundredth part of whatthey are at present capable of performing, in conse-quence of a proper division and combination of theirdifferent operations.
This passage highlights the enormous productivity gains from specialization. It made me think about how much we underestimate the impact of dividing labor into focused tasks. I’m curious about the broader implications: does this extreme efficiency imply that modern economies are even more fragile because individual skills are highly specialized and dependent on complex interconnections?
All course readings will be available on Canvas. There is no required textbook
I like the idea that we do not need to be constricted to buying a textbook. That saves some money and makes the class more obtainable to complete everything. I just struggle sometimes understanding how to do assignments on different websites.
It's not: Can schools save more of our students? Because I think we have the answer to that -- and it's yes they can, if we save our schools first. We can start by caring about the education of other people's children ...
Tying the amount of money we have lost as a nation to the lack of attention paid to the education system was an interesting point. The financial loss could sway people who previously did not care about other people's children (and their education). Due to the current state of the country it may be difficult to get people to "start caring about other people's children." in tems of improving the condition of our current educational system but the financial implications and losing earning potential could sway stakeholders to invest in educational reform.
And as I sat there on the other side of the glass from them, idealistic with a college degree, I wondered to myself: Why didn't schools do something more to prevent this from happening?
I have had a similar experience when my district required that I teach alternative education students. I was often disheartened by my experiences with that group of students. Witnessing violence and lack of will to learn in such a restricted setting was disturbing. My experience cemented my understanding that students should receive more preventative services to positively impact their lives.
Unlike shallow learning methods that required humans to carefully engineer features, deep learning networks can automatically discover useful features directly from raw data
difference between shallow and deep learning lied in teh amount o fdata. the shallow learning methods rely on humans to state what features to "notice"?
Third, we discovered an inherent tension between precision (being right when we make a prediction) and recall (catching all the cases we should find), forcing designers to make explicit trade-offs based on their application’s needs.
how are designers implementing precision versus recall?
Black farmers often turned to sharecropping
Sharecropping was slavery lite. In the sense that while the were “paid” they still were under the same harsh conditions as before.
Black delegates actively participated in revising state constitutions. One of the most significant accomplishments of these conventions was the establishment of a public school system.
I believe that the black delegates tried there best to create a space for newly freed Africans. To make sure laws reflected the nations they wished to live in. Also creating a public school system after not being able to access to reading was a amazing feat.
Eric Schmidt once said about online privacy and Google, “If you have something that you don’t want anyone to know, maybe you shouldn’t be doing it in the first place.” While this might make sense in a free society, there are many places in the world — North Korea for example — where government surveillance can utilize corporate invasions of privacy to crack down on dissent and severely limit freedom.
This is a particularly scary aspect of this article. I think today we have almost no privacy unfortunately. While I don't think it is nearly as bad in the US I think it is steadily getting worse. I find it very concerning that a lot of tech and media giants will advertise on being private but in reality that's not the case. While I do agree that if you are doing/saying something that you wouldn't be okay with people knowing you probably shouldn't do it online but also I feel users should be entitled to some level of privacy.
Online fandoms may simultaneously expect less centralized authority over the fan experience and more direct access to their heroes. They often expect to see transparency during the creative process, such as Instagram or Twitter posts with “secret” messages for longtime followers or behind-the-scenes videos as albums and movies are made. Fandoms might demand to hear key information first or to have special access via social media.
This is an interesting phenomenon. I think that fandoms aren't inherently negative but I do think this causes some dangers. I think that this had led people to feel obligated to information about celebrities or other public figures. I've seen lots of public figures have to set boundaries with their fans about not wanting to share every aspect of their life. This sometimes leads fans to feel "betrayed". I personally think it's odd to expect a person who you do not know to let you in on every part of their life. I think social media has made people feel as though they are obligated to that.
The Internet is the first thing that humanity has built that humanity doesn’t understand, the largest experiment in anarchy that we have ever had
I think this is an interesting take. I don't necessarily agree with it. While I think that humans greatly underestimated what the internet would become I think we have the ability to understand and regulate it. A common issue with the internet is the lack of regulation. I think that the lack of regulation is due to the profit incentive. Like we talked about on Thursday, the media is a lobby that benefits politicians and their refusal to regulate it keeps them rich.
Ms Skidd spent about 20 hours rewriting the copy, charging $100 (£74)an hour. Rather than making small changes, she "had to redo the wholething"
Its she could charge so much to fix something that the company should have just had right from the start
However good copyediting, like writing, takes time because you need tothink and not curate like Al, which also doesn't understand nuance wellbecause it's curating the data.
This is so true. Some people think it takes just a little bit to get good quality writing but it takes so much longer than that and AI has just ruined what people think.
Generative AI tools also carry the potential for otherwise misleading outputs. AI tools like ChatGPT, Copilot, and Gemini have been found to provide users with fabricated data that appears authentic.
This information is mind blowing. These tool (especially ChatGPT) are use so frequently. When you get the information you would think all information would be accurate. Especially with these tools being used in professional/ school settings.