https://www.revolutionaryplayers.org.uk/the-scope-and-nature-of-darwins-commonplace-book/
Erasmus Darwin's commonplace book
It is one of the version(s?) published by John Bell based on John Locke's method and is a quarto volume bound in vellum with about 300 sheets of fine paper.
Blank pages 1 to 160 were numbered and filled by Darwin in his own hand with 136 entries. The book was started in 1776 and continued until 1787. Presumably Darwin had a previous commonplace book, but it has not been found and this version doesn't have any experiments prior to 1776, though there are indications that some material has been transferred from another source.
The book contains material on medical records, scientific matters, mechanical and industrial improvements, and inventions.
The provenance of Erasmus Darwin's seems to have it pass through is widow Elizabeth who added some family history to it. It passed through to her son and other descendants who added entries primarily of family related topics. Leonard Darwin (1850-1943), the last surviving son of Charles Darwin gave it to Down House, Kent from whence it was loaned to Erasmus Darwin House in 1999.