- Sep 2020
-
psyarxiv.com psyarxiv.com
-
Lange, Ann-Marie G de, Tobias Kaufmann, Daniel S Quintana, Adriano Winterton, Lars T. Westlye, and Klaus P. Ebmeier. ‘Risk Factors Associated with Loneliness, Social Isolation, and Neuroticism in the UK Biobank Cohort’. Preprint. PsyArXiv, 21 September 2020. https://doi.org/10.31234/osf.io/q8kjv.
Tags
- unhealthy lifestyle
- COVID-19
- aging
- United Kingdom
- public health
- cardiovascular risk
- is:preprint
- depression
- risk factor
- social isolation
- comorbidities
- Biobank
- neuroticism
- physical health
- vulnerable
- UK
- lang:en
- socioeconomic conditions
- social deprivation
- loneliness
- social health
- mental health
Annotators
URL
-
-
www.healthline.com www.healthline.com
-
Blood Thinners, Blood Pressure Meds May Improve COVID-19 Survival Rate. (2020, August 27). Healthline. https://www.healthline.com/health-news/blood-thinners-blood-pressure-meds-may-improve-covid-19-survival-rate
-
- Jun 2020
-
www.cdc.gov www.cdc.gov
-
Stokes, E. K. (2020). Coronavirus Disease 2019 Case Surveillance—United States, January 22–May 30, 2020. MMWR. Morbidity and Mortality Weekly Report, 69. https://doi.org/10.15585/mmwr.mm6924e2
-
-
psyarxiv.com psyarxiv.com
-
Hyland, P., Shevlin, M., Karatzias, T., & Jowett, S. (2020). Somatisation and COVID-19 related Posttraumatic Stress Disorder symptoms: The role of hyperarousal [Preprint]. PsyArXiv. https://doi.org/10.31234/osf.io/bywu7
-
-
elemental.medium.com elemental.medium.com
-
Smith, Dana G. ‘Coronavirus May Be a Blood Vessel Disease, Which Explains Everything’. Medium, 31 May 2020. https://elemental.medium.com/coronavirus-may-be-a-blood-vessel-disease-which-explains-everything-2c4032481ab2.
-
- May 2020
-
www.mittellaendische.ch www.mittellaendische.ch
-
COVID-19—Eine Zwischenbilanz oder eine Analyse der Moral, der medizinischen Fakten, sowie der aktuellen und zukünftigen politischen Entscheidungen. (2020, April 7). DIE MITTELLÄNDISCHE ZEITUNG - FÜR MEHR DURCHBLICK. https://www.mittellaendische.ch/2020/04/07/covid-19-eine-zwischenbilanz-oder-eine-analyse-der-moral-der-medizinischen-fakten-sowie-der-aktuellen-und-zuk%C3%BCnftigen-politischen-entscheidungen/
Tags
- China
- COVID-19
- comparison
- is:news
- moral
- post COVID-19
- influenza
- cardiovascular
- Trump
- Switzerland
- USA
- lang:de
- EU
- origin
- media
- mortality
Annotators
URL
-
- Apr 2020
-
www.thelancet.com www.thelancet.com
-
Horton, R. (2020). Offline: COVID-19—bewilderment and candour. The Lancet, 395(10231), 1178. https://doi.org/10.1016/S0140-6736(20)30850-3
-
-
jamanetwork.com jamanetwork.com
-
In the present study, we also found that markers of inflammatory response, such as C-reactive protein, procalcitonin, and leukocytes, were significantly increased among patients who suffered from cardiac injury. The activation or enhanced release of these inflammatory cytokines can lead to apoptosis or necrosis of myocardial cells.
-
-
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
-
Third, Huang’s study noted that high concentration of IL-1β, IFN-γ, IP-10 and MCP-1 could be detected in patients infected with 2019-nCoV, which might lead to activated T-helper-1 (Th1) cell responses [4]. Furthermore, they also found that ICU patients had much higher concentrations of inflammatory factors than those non-ICU patients, suggesting that the cytokine storm was associated with disease severity
-
Second, hypoxaemia may be also an important reason of cardiac injury. In Huang’s study, 32% COVID-19 patients had various degree of hypoxaemia and need required high-flow nasal cannula or higher-level oxygen support. In Chen’s study, up to 76% of patients require oxygen therapy. Due to severe 2019-nCoV infection, the pneumonia may cause significant gas exchange obstruction, leading to hypoxaemia, which significantly reduces the energy supply by cell metabolism, and increases anaerobic fermentation, causing intracellular acidosis and oxygen free radicals to destroy the phospholipid layer of cell membrane. Meanwhile, hypoxia-induced influx of calcium ions also leads to injury and apoptosis of cardiomyocytes.
-
-
www.nature.com www.nature.com
-
The mechanism of acute myocardial injury caused by SARS-CoV-2 infection might be related to ACE2. ACE2 is widely expressed not only in the lungs but also in the cardiovascular system and, therefore, ACE2-related signalling pathways might also have a role in heart injury.
-
Other proposed mechanisms of myocardial injury include a cytokine storm triggered by an imbalanced response by type 1 and type 2 T helper cells
-
Among the people who died from COVID-19 reported by the NHC, 11.8% of patients without underlying CVD had substantial heart damage, with elevated levels of cTnI or cardiac arrest during hospitalization.
-
and respiratory dysfunction and hypoxaemia caused by COVID-19, resulting in damage to myocardial cells.
-
some of the patients first went to see a doctor because of cardiovascular symptoms. The patients presented with heart palpitations and chest tightness rather than with respiratory symptoms, such as fever and cough, but were later diagnosed with COVID-19.
-
-
jamanetwork.com jamanetwork.com
-
Common complications among the 138 patients included shock (12 [8.7%]), ARDS (27 [19.6%]), arrhythmia (23 [16.7%]), and acute cardiac injury (10 [7.2%]). Patients who received care in the ICU were more likely to have one of these complications than non-ICU patients.
-