381 Matching Annotations
  1. Last 7 days
    1. Posted byu/jackbaty4 hours agoCard sizes .t3_xib133._2FCtq-QzlfuN-SwVMUZMM3 { --postTitle-VisitedLinkColor: #9b9b9b; --postTitleLink-VisitedLinkColor: #9b9b9b; --postBodyLink-VisitedLinkColor: #989898; } I've been on-again/off-again with paper for PKM, but one thing remains consistent each time: I don't enjoy using 4x6 index cards. I much prefer 3x5-inch cards. I realize that it's irrational, but there it is.My question is if I dive into building an antinet, will I regret using 3x5 cards? I already have hundreds of them. I have dividers, holders, and storage boxes for them. I just prefer how they _feel_, as weird as that sounds.I'd like to hear if people are using 3x5 cards successfully or if you've come to regret it.

      While it may be slightly more difficult to find larger metal/wood cases for the 4x6 or 5x8 cards, it's a minor nuisance and anyone who wants them will eventually find the right thing for them. Beyond this, choose the card size that feels right to you.

      If you don't have an idea of what you need or like, try things out for 10-20 cards and see how it works for you, your handwriting size, and general needs. People have been using 3x5, 4x6, and even larger for hundreds of years without complaining about any major issues. If Carl Linnaeus managed to be okay with 3x5, which he hand cut by the way, I suspect you'll manage too.

      Of course I won't mention to the Americans the cleverness of the A6, A5, A4 paper standards which allows you to fold the larger sizes in half to get the exact next smaller size down. Then you might get the benefit of the smaller size as well as the larger which could be folded into your collection of smaller cards, you just have to watch out for accidentally wrapping ("taco-ing") a smaller card inside of a larger one and losing it. I suppose you could hand cut your own 5" x 6" larger cards to do this if you found that you occasionally needed them.

      For the pocketbook conscious, 3x5 does have the benefit of lower cost as well as many more options and flexibility than larger sizes.

      At least commercial card sizes are now largely standardized, so you don't have deal with changing sizes the way Roland Barthes did over his lifetime.

      My personal experience and a long history of so many manuals on the topic saying "cards of the same size" indicates that you assuredly won't have fun mixing different sized slips together. I personally use 3x5" cards in a waste book sense, but my main/permanent collection is in 4x6" format. Sometimes I think I should have done 3 x 5, but it's more like jealousy than regret, particularly when it comes to the potential of a restored fine furniture card catalog. But then again...

  2. Sep 2022
  3. Aug 2022
  4. Jul 2022
    1. when we die we go through eight stages according to the buddhist understanding and each of those stages the first four the elements the sort of solidity if you will i we know they're 01:16:07 not solid but from a conventional perspective the solidity elements the liquidity elements the thermodynamic elements the movement the kinetic elements those all dissolve as we die in 01:16:19 the first four and when that fourth one happens there's no more circulation of blood or of air so we don't breathe we have no circulatory you know blood pressure so we're declared clinically dead but 01:16:30 there's four more stages we go through and those are when the mind becomes successively subtler and those are when we get into the non-dual minds that are the most subtle minds and the last 01:16:43 eighth stage it's called worser in tibetan and we translate that as luminosity or clear light it's not light it's not you know but it's the most utter clear clear mind 01:16:57 and that mind if it goes on if we don't die if we meditate on that luminosity and sustain it through our meditation infinitely we can become a buddha and that's why the buddha is 01:17:09 sometimes called a buddhism an enlightened buddha is a deathless state because you don't actually die so those would be the non-conceptual and non-dual minds and just for completeness 01:17:23 those last four minds are called these are technical terms so it won't make much it won't have much give you much understanding white appearance red increase black near attainment and then this worst air this 01:17:35 luminosity so that's kind of the the the road map if you will for for mine and it's not the brain now on the gross level of thinking in our sensory minds there's a very close 01:17:48 connection with you know meant with the brain okay but when you die the brain is supposed to be dead and you're still alive okay and so these more subtle minds 01:18:01 are not related actually to the brain so we could really say that mind is experience it's awareness it's knowing not knowing something but 01:18:12 the act of knowing so the qualities of mind the most important qualities are awareness and clarity so that gives you just some rough idea of the buddhist understanding of mind or consciousness

      Barry gives an explanation of the different levels of mind as the body undergoes death, and particularly, the last 4 of 8 progressively subtler states of mind that are nondual, and therefore, not considered as part of the brain.

  5. Jun 2022
  6. May 2022
    1. You can use a heuristic: only change strings that have one of the bad characters in them, like â. This works well if a character like â won’t ever appear in a valid string. The last time I fixed this kind of bug, though, I wanted to play it safe. I used another useful tool to help: my eyes. Whenever I found a badly encoded string, I printed it out, along with its replacement:
      • no magic solutions!
    2. It seems like those three bytes should be read as UTF-8, where they’d represent a curly quote. Instead, each byte is showing up as a different character. So, which encoding would represent [226, 128, 153] as ’? If you look at a few tables of popular encodings, you’ll see it’s Windows-1252.

      -In UTF8 are 3 bytes - In W1252 a byte= a char

    1. This only forces the client which encoding to use to interpret and display the characters. But the actual problem is that you're already sending ’ (encoded in UTF-8) to the client instead of ’. The client is correctly displaying ’ using the UTF-8 encoding. If the client was misinstructed to use, for example ISO-8859-1, you would likely have seen ââ¬â¢ instead.
      • HERE IT IS!
    2. This answer is not useful Show activity on this post. So what's the problem, It's a ’ (RIGHT SINGLE QUOTATION MARK - U+2019) character which is being decoded as CP-1252 instead of UTF-8. If you check the encodings table, then you see that this character is in UTF-8 composed of bytes 0xE2, 0x80 and 0x99. If you check the CP-1252 code page layout, then you'll see that each of those bytes stand for the individual characters â, € and ™.
      • HERE IT IS!
    1. DICER1 syndrome encompasses a variety of benign and malignant manifestations including multinodular goitre

      Gene: DICER1 PMCID: PMC8451242 PMID: 34552563 Pathogenic Inheritance Pattern: Autosomal Dominant MultipleDiseaseEntities Disease Entity: DICER1 syndrome, multinodular goitre, cystic nephroma, anaplastic renal sarcoma, Wilms tumour, differentiated thyroid carcinoma, gynandroblastoma, ciliary body medulloepithelioma, embryonal rhabdomyosarcoma, pineoblastoma, pituitary blastoma, kidney cyst, pulmonary cyst, Sertoli-Leydig Cell Tumor. Mutation: Germline MultipleGeneVariants Variant & Clinvar IDs: c.3452_3453del (485534), c.316del (no ClinVar ID), c.171_172insAC (no ClinVar ID), c.3434del (no ClinVar ID), c.988C>T (933007), c.5388dup (no ClinVar ID) Zygosity: None provided. Case: At time of operation, the goitre patients living in Denmark were ages 21, 12, 21, 8, 14, and 16. Four underwent total thyroidectomies, and two underwent partial thyroidectomies. The patient originally aged 21 previously had a kidney cyst at age 14 and a pulmonary cyst at an unknown age. The patient aged 14 at time of partial thyroidectomy later manifested a Sertoli-Leydig Cell Tumor at age 15. All six patients were female. CasePresentingHPO: None provided. CasePreviousTesting: thyroidectomy gnomAD: ENSG00000100697.10, https://gnomad.broadinstitute.org/gene/ENSG00000100697 Mutation Type: Frameshift, Nonsense

    1. This works for me: PowerShell -Command "TREE /F | Out-File output.txt -Encoding utf8"
      • WITH POWERSHELL
    2. You should add this command chcp 65001 before dir command to change code page to UTF-8 @echo off CHCP 65001>nul dir>1.txt Further reading about CHCP command
      • DIR NAMES IN UTF-8
    1. Most European keyboards have keycap labels for the apostrophe and both accents. These have always looked like in the ISO and Unicode standards. The photo below shows the relevant keys highlighted on a standard German PC keyboard, which has the acute/grave accent key left and the number-sign/apostrophe key below the backspace key:
      • unicode!
  7. Mar 2022
  8. Dec 2021
    1. spoken or written word.

      AND non verbal conduct. Not sure if this counts as a flaw. Its missing a part.

    2. the Court could also decide that the state doesn't have a legitimate interest in the question of flag desecration

      I believe this is incorrect: I think this is the correct reasoning regarding legitimate interest in the question of flag desecration "we do not doubt that the government has a legitimate interest in making efforts to "preserv[e] the national flag as an unalloyed symbol of our country."

  9. Nov 2021
    1. that government may always prohibit the expression of an idea whenever society finds the idea itself offensive or disagreeable.

      incorrect, the government may not always prohibit the expression of an idea when...

    1. Simmons-Harris sued, charging that the voucher program violated the First Amendment's free exercise clause because only 10 percent of the private schools available were religious, and only 5 percent of students used their vouchers at private schools.

      This area is incorrect, the books version states, "Although no public schools from adjacent districts opted to participate in the program, fifty-six private schools, 80 percent of them religious, did. Religious schools were the choice of the parents of 97 percent of the students who used tuition vouchers to attend private schools."

    1. offend the 14th Amendment to the Constitution

      Incorrect - "Does the voucher program offend the establishment clause..." is the correct legal issue here

  10. Oct 2021
  11. Sep 2021
    1. les directeurs d'école et les chefs d'établissement doivent communiquer aux associations de parents d'élèves qui en font la demande la liste des parents d'élèves de l'école ou de l'établissement scolaire mentionnant leurs noms et adresses postale et électronique
  12. Aug 2021
  13. Jul 2021
  14. Jun 2021
    1. Angular is nothing but an open-source web application framework. It is being led by the Angular Team at Google and also by a community of individuals and corporations. It is based on TypeScript.Angular is a complete rewrite from the same team that had built AngularJS. It can be used as the frontend of the MEAN stack, which consists of the MongoDB database, Express.js web application server framework, Angular itself (or AngularJS), and the Node.js server runtime environment.

      Top Angular 8 Interview Questions to get you ready

  15. May 2021
  16. Mar 2021
    1. Results for individual PALB2 variants were normalized relative to WT-PALB2 and the p.Tyr551ter (p.Y551X) truncating variant on a 1:5 scale with the fold change in GFP-positive cells for WT set at 5.0 and fold change GFP-positive cells for p.Y551X set at 1.0. The p.L24S (c.71T>C), p.L35P (c.104T>C), p.I944N (c.2831T>A), and p.L1070P (c.3209T>C) variants and all protein-truncating frame-shift and deletion variants tested were deficient in HDR activity, with normalized fold change <2.0 (approximately 40% activity) (Fig. 1a).

      AssayResult: 7.3

      AssayResultAssertion: Normal

      StandardErrorMean: 0.08

    2. A total of 84 PALB2 patient-derived missense variants reported in ClinVar, COSMIC, and the PALB2 LOVD database were selected

      HGVS: NM_024675.3:c.1145G>T p.(Ser382Ile)

    1. SUPPLEMENTARY DATA

      AssayResult: 58

      AssayResultAssertion: Indeterminate

      PValue: < 0.0001

      Approximation: Exact assay result value not reported; value estimated from Figure 6C.

    2. SUPPLEMENTARY DATA

      AssayResult: -32

      AssayResultAssertion: Abnormal

      PValue: < 0.0001

    3. SUPPLEMENTARY DATA

      AssayResult: 76.45

      AssayResultAssertion: Indeterminate

      PValue: 0.0001

      Comment: Exact values reported in Table S3.

    4. To this end, 44 missense variants found in breast cancer patients were identified in the ClinVar database (https://www.ncbi.nlm.nih.gov/clinvar) and/or selected by literature curation based on their frequency of description or amino acid substitution position in the protein (Supplemental Table S1).

      HGVS: NM_024675.3:c.23C>T p.(Pro8Leu)

    1. Source Data

      AssayResult: 83.96

      AssayResultAssertion: Not reported

      ReplicateCount: 2

      StandardErrorMean: 9.89

      Comment: Exact values reported in “Source Data” file.

    2. Source Data

      AssayResult: 66.19

      AssayResultAssertion: Not reported

      ReplicateCount: 2

      StandardDeviation: 21.26

      StandardErrorMean: 15.03

      Comment: Exact values reported in “Source Data” file.

    3. We, therefore, analyzed the effect of 48 PALB2 VUS (Fig. 2a, blue) and one synthetic missense variant (p.A1025R) (Fig. 2a, purple)29 on PALB2 function in HR.

      HGVS: NM_024675.3:c.1250C>A p.(S417Y)

    1. Most Suspected Brugada Syndrome Variants Had (Partial) Loss of Function

      AssayResult: 1.2

      AssayResultAssertion: Abnormal

      ReplicateCount: 11

      StandardErrorMean: 0.7

      Comment: This variant had loss of function of peak current (<10% of wildtype), therefore it was considered abnormal (in vitro features consistent with Brugada Syndrome Type 1). (Personal communication: A. Glazer)

    2. we selected 73 previously unstudied variants: 63 suspected Brugada syndrome variants and 10 suspected benign variants

      HGVS: NM_198056.2:c.1156G>A p.(Gly386Arg)

    1. RRID:ZFIN_ZDB-ALT-120221-8

      DOI: 10.7554/eLife.64267

      Resource: (ZFIN Cat# ZDB-ALT-120221-8,RRID:ZFIN_ZDB-ALT-120221-8)

      Curator: @scibot

      SciCrunch record: RRID:ZFIN_ZDB-ALT-120221-8


      What is this?

    2. RRID:ZFIN_ZDB-ALT-041129-8

      DOI: 10.7554/eLife.64267

      Resource: (ZFIN Cat# ZDB-ALT-041129-8,RRID:ZFIN_ZDB-ALT-041129-8)

      Curator: @scibot

      SciCrunch record: RRID:ZFIN_ZDB-ALT-041129-8


      What is this?

  17. Feb 2021
    1. Supplemental material

      AssayResult: 86

      AssayResultAssertion: Normal

      Comment: See Table S3 for details

    2. Supplemental material

      AssayResult: 6.1

      AssayResultAssertion: Abnormal

      Comment: See Table S3 for details

    3. We analysed a total of 82 blood samples derived from 77 individuals (online supplemental table 3). These 77 individuals corresponded either to new index cases suspected to harbour a pathogenic TP53 variant or to relatives of index cases harbouring TP53 variants.

      HGVS: NM_000546.5:c.215C>A p.(Pro72His)

    1. cloud computing shall not be referred to as the future, but rather a trend deepening its root in the present. So when many businesses are migrating to cloud or hybrid servers, how can healthcare players sit back.

      As technology is evolving and growing, cloud computing is entering a diverse set of fields. Currently, it’s enjoying a high rise in the healthcare industry.

  18. Jan 2021
  19. Nov 2020
  20. Sep 2020
    1. of which the handle [was x minas] of gold, he provided for his friend.

      It shows the his friend Enkidu.

    2. o Enkidu, may the paths [of] the Forest of Cedar mourn you [without pause,] by day and by night!

      Message of Gilgamesh to Enkidu when he died.

    3. Gilgamesh [began mourning] his friend:

      It shows their friendship.

    1. À cette fin, comme le prévoit l'article D. 111-8 du Code de l'éducation, les directeurs d'école et les chefs d'établissement doivent communiquer aux associations de parents d'élèves qui en font la demande la liste des parents d'élèves de l'école ou de l'établissement scolaire mentionnant leurs noms, adresses postale et électronique, à la condition que ceux-ci aient donné leur accord exprès à cette communication.
  21. Jan 2020
    1. RRID:ZFIN_ZDB-ALT-011017-8

      DOI: 10.7554/eLife.42881

      Resource: (ZFIN Cat# ZDB-ALT-011017-8,RRID:ZFIN_ZDB-ALT-011017-8)

      Curator: @evieth

      SciCrunch record: RRID:ZFIN_ZDB-ALT-011017-8


      What is this?

    1. 8
    2. 8
    3. 8
    4. 8
    5. muscular hypotonia
    6. motor development
    7. speech and language development
  22. Dec 2019
  • Jul 2019
    1. Nobel Peace prize

      What did he do to win the noble prize?

    2. We deplore all forms of violence

      They are non-violent

    1. Distribution of antibiotic resistance genes in Vibriofrom Cochin estuary, shrimp farm and seafood
    1. Estimation of bioaccumulation of trace metals inmuscle and gill tissue of fish, Labeo rohita
  • Jun 2019
    1. Post vaccination enhanced expression of activation marker CD69 and Chemokine receptor CCR5 on memory B cells in HBV positive newborns
    1. concentrators (Amicon), and subjected to reduction with 0.0.5 M sodium dithionite. For this an appropriate amount of anaerobically prepared dithionite solution was added to the reconstituted Hb and the reaction mixture was quickly passed through a Sephadex G25 gel filtration column (30 em x 1.5 em) equilibrated with 0.05 M Tris HCI (pH 7.4), in order to minimize the duration of contact of dithionite with the protein. The reduced Hb was dialyzed extensively against 0.01 M potassium phosphate buffer (pH 6.5) and loaded onto a CM52 column (1 Ocm x 1.5cm) equilibrated with the same buffer. A linear gradient of 150 ml each of 0.01 M potassium phosphate buffer (pH 6.5) and 0.015 M potassium phosphate buffer (pH 8.5) was employed to elute the protein from the column
    2. Construction of mutant a globins
    3. Reconstitution of a globin and rf chain into HbS tetramers
  • May 2019