1. Aug 2024
    1. Big Blue Gets Renewed by [[Joe Van Cleave]]

      I like the aftermarket upgrades you've made.

      The Cheers reference reminds me that I've been trying to pair drinks with machines as I write. I had a blue cocktail on a cruise to Alaska last year that used glacier ice (which is blue), but since that's not easy to source in ABQ, maybe try an "Electric Iced Tea" which is a variation on the Long Island iced tea but which swaps blue curaçao for the triple sec and a clear lemon-lime based soda for the cola.

    1. Eyewitness Misidentification

      This is a surprising fact because with TV shows they make it seem like eye witnesses know for sure who they see so these statistics for eyewitness misidentification is very surprising information

    2. Suggestibility describes the effects of misinformation from external sources that leads to the creation of false memories

      This is a tricky fact because that can make it very difficult for the police to make sure they are getting the correct details. I know from peoples stories that my memories can alter in my brain so it is very tricky with suggestibility.

    1. A flashbulb memory

      This is a very interesting fact. I never knew this was what it was called or why momentous events can be so easily memorized because everyone talks about when a moment big enough like 9/11 happens people will forget specific details.

    1. “And did you see where I was seated, Mance?” He leanedforward. “Did you see where they put the bastard?”Mance Rayder looked at Jon’s face for a long moment. “I think wehad best nd you a new cloak,” the king said, holding out his hand.

      there is some truth to this :(

    2. She was dead, as it happened, but her daughter saw to me.Cleaned my wounds, sewed me up, and fed me porridge and potionsuntil I was strong enough to ride again. And she sewed up the rentsin my cloak as well, with some scarlet silk from Asshai that hergrandmother had pulled from the wreck of a cog washed up on theFrozen Shore. It was the greatest treasure she had, and her gift tome.” He swept the cloak back over his shoulders. “But at theShadow Tower, I was given a new wool cloak from stores, black andblack, and trimmed with black, to go with my black breeches andblack boots, my black doublet and black mail. The new cloak had nofrays nor rips nor tears ... and most of all, no red. The men of theNight’s Watch dressed in black, Ser Denys Mallister reminded mesternly, as if I had forgotten. My old cloak was t for burning now,he said.“I left the next morning ... for a place where a kiss was not acrime, and a man could wear any cloak he chose.”

      the beginning kinda reminds me of robb and jeyne but red is such a specific color..

    3. “Bael the Bard,” said Jon, remembering the tale that Ygritte hadtold him in the Frostfangs, the night he’d almost killed her.“Would that I were. I will not deny that Bael’s exploit inspiredmine own ... but I did not steal either of your sisters that I recall.

      hmm interesting

    4. I was walking the wall around the yard when I came onyou and your brother Robb. It had snowed the night before, and thetwo of you had built a great mountain above the gate and werewaiting for someone likely to pass underneath.”“I remember,” said Jon with a startled laugh. A young blackbrother on the wallwalk, yes ... “You swore not to tell.”“And kept my vow. That one, at least.”

      oh sweet

    5. Mance Rayder laughed. “As you wish. Jon Snow, before youstands Tormund Giantsbane, Tall-talker, Horn-blower, and Breakerof Ice. And here also Tormund Thunderst, Husband to Bears, theMead-king of Ruddy Hall, Speaker to Gods and Father of Hosts.”

      oh he's a wildling? HOW DID BRAIME GET TO THE WALL WHAT

    6. his ragged black woolcloak,

      he still keeps the watch with him?

    7. The singer rose to his feet. “I’m Mance Rayder,” he said as he putaside the lute. “And you are Ned Stark’s bastard, the Snow ofWinterfell.”

      yup had a feeling

    8. Jon felt utterly alone as he stood there in hisblacks, awaiting the pleasure of the turncloak who called himselfKing-beyond-the-Wall. When his eyes had adjusted to the smoky redgloom, he saw six people, none of whom paid him any mind. A darkyoung man and a pretty blonde woman were sharing a horn ofmead. A pregnant woman stood over a brazier cooking a brace ofhens, while a grey-haired man in a tattered cloak of black and redsat crosslegged on a pillow, playing a lute and singing:

      kinda reminds me sansa meeting the tyrells like metting a king while she met a queen, a blonde women and a pregnant one

    9. to play the part of turncloak,

      yeah him and theon are polar opposites

    10. The wildlings had taken him foran oathbreaker, but in his heart he was still a man of the Night’sWatch, doing the last duty that Qhorin Halfhand had laid on him.Before I killed him.

      a dutiful traitor

    11. “Willas has a bad leg but a good heart,” said Margaery. “He usedto read to me when I was a little girl, and draw me pictures of thestars. You will love him as much as we do, Sansa.”

      a good man in westeros? now thats rare

    12. “I CALLED FOR A KNIGHT, BUT YOU’RE A BEAR! A BEAR! ABEAR! ALL BLACK AND BROWN AND COVERED WITH HAIR!”

      oo foreshadowing

    13. Oberyn Martell.

      interestingg

    14. We were speaking of my grandson Willas. He is a bit oldfor you, to be sure, but a dear boy for all that. Not the least bitoash, and heir to Highgarden besides.”

      ok but WHY

    15. rose. Ser Loras in white silk, so pure, innocent, beautiful. Thedimples at the corner of his mouth when he smiled. The sweetnessof his laugh, the warmth of his hand. She could only imagine whatit would be like to pull up his tunic and caress the smooth skinunderneath, to stand on her toes and kiss him, to run her ngersthrough those thick brown curls and drown in his deep brown eyes.A ush crept up her neck.

      FUCKK SHES SO IN LOVE :((

    16. “I want you to tell me the truth about this royal boy,” said LadyOlenna abruptly. “This Jorey.”

      ok so thats what she was after

    17. All these kings would do a dealbetter if they would put down their swords and listen to theirmothers.”

      YUP

    18. “That Varys creature seemed tothink we should be grateful for the information. I

      now what is he scheming...

    19. . She felt very like a pu shherself.

      aww lmao

    20. After LordPu Fish

      HIT AFTER HIT BRO

    21. As to your father, would that I’d been born a peasant woman with abig wooden spoon, I might have been able to beat some sense intohis fat head.”

      lmao

    22. The Baratheons have always had some queernotions, to be sure. It comes from their Targaryen blood, I shouldthink.” She snied. “They tried to marry me to a Targaryen once,but I soon put an end to that.”

      the way she was engaged to a gay targ and is now talking about another one now lmao

    23. The old woman smelled of rosewater. Why, she’s just the littlest bitof a thing. There was nothing the least bit thorny about her.

      sureee

    24. “Their mothernamed them Erryk and Arryk, but Grandmother can’t tell themapart, so she calls them Left and Right.”

      erryk and arryk lmao

    25. Maidenvault since King Baelor the Blessed had conned his sisterstherein, so the sight of them might not tempt him into carnalthoughts.

      ICK

    26. He took his hand from her arm. “I slew Robar at Storm’s End, mylady.” It was not a boast; he sounded sad.Him, and another of King Renly’s Rainbow Guard as well, yes. Sansahad heard the women talking of it round the well, but for a momentshe’d forgotten. “That was when Lord Renly was killed, wasn’t it?How terrible for your poor sister.”“For Margaery?” His voice was tight. “To be sure. She was atBitterbridge, though. She did not see.”“Even so, when she heard ...”Ser Loras brushed the hilt of his sword lightly with his hand. Itsgrip was white leather, its pommel a rose in alabaster. “Renly isdead. Robar as well. What use to speak of them?”The sharpness in his tone took her aback. “I ... my lord, I ... I didnot mean to give oense, ser.”“Nor could you, Lady Sansa,” Ser Loras replied, but all thewarmth had gone from his voice. Nor did he take her arm again.

      YES IVE BEEN WAITING FOR HIS GRIEF

    27. Ser Loras gave her a modest smile. “I spoke only a simple truth,that any man with eyes could see.”He doesn’t remember, Sansa realized, startled. He is only being kindto me, he doesn’t remember me or the rose or any of it. She had been socertain that it meant something, that it meant everything. A red rose,not a white. “It was after you unhorsed Ser Robar Royce,” she said,desperately.

      :( sorry girl not this guy

    28. Garlan

      oo yes more siblings

    29. I am talking to him, and he’s touching me, he’sholding my arm and touching me.

      can't even blame her cuz he sounds so good

    30. The sight of Ser Loras Tyrell standing on herthreshold made Sansa’s heart beat a little faster.

      wait yess

    31. if there was one thing that Sansa Stark had learnedhere, it was mistrust

      a lesson she learned painfully :(

    32. Hermother and grandmother followed close behin

      yess

    33. She was sixteen

      THE WAY NOT LIKE US STARTED PLAYING

    34. the heart-shaped face, the red eyes, the long coppery hair, herred gowns moving like ames as she walked

      like the burning heart of azhor ahai

    35. My luck. His shortened ngers patted at his chest,groping, nding nothing. The pouch was gone, and the ngerboneswith them. S

      noo

    36. Instead he sucked in a great gulp of air and dove

      deez nutz

    37. Why should I live? he thought as tears blurred his vision. Gods begood, why? My sons are dead, Dale and Allard, Maric and Matthos,perhaps Devan as well. How can a father outlive so many strong youngsons? How would I go on? I am a hollow shell, the crab’s died, there’snothing left inside. Don’t they know that?

      catelyn core

    38. You, who killed your mother to come into theworld?

      blmaing an infant is crazy

    39. “Jorey and Margaery shall marry on the rst day of the newyear, which as it happens is also the rst day of the new century.The ceremony will herald the dawn of a new era.”

      WHATTT

    40. Uncle Tygett, a boy of thirteen. Hehad vanished in the riot, not long after wedding the LadyErmesande, a suckling babe who happened to be the last survivingheir of House Hayford. And likely the rst bride in the history of theSeven Kingdoms to be widowed before she was weaned.

      what WHAT

    41. My hirelings betray me, my friends are scourged and shamed, and I liehere rotting, Tyrion thought. I thought I won the bloody battle. Is thiswhat triumph tastes like?

      sigh its all falling apart

    42. She was no little girl in the dream; she was a wolf, huge andpowerful, and when she emerged from beneath the trees in front ofthem and bared her teeth in a low rumbling growl, she could smellthe rank stench of fear from horse and man alike. The Lyseni’smount reared and screamed in terror, and the others shouted at oneanother in mantalk, but before they could act the other wolves camehurtling from the darkness and the rain, a great pack of them, gauntand wet and silent.

      warging with nymeria!!

    43. It was mushy andoverripe, but she ate it worms and all.

      ew

    44. she wore a sword across her back,

      wheres needle :(

    45. Tully men did not surrender easily, no matter theodds.

      seeing that in oscar tullys grandpa too LIKE IT TOOK ALYS DOING SOME MAGIC TO KILL HIM

    46. “Your son will be heir to Winterfell andmine to the Eyrie. Oh, they’ll be the best of friends, like your Nedand Lord Robert. They’ll be more brothers than cousins, truly, I justknow it.” She was so happy.

      stop its so sad how distant they all are now

    47. Could Tansy be some pet name he called Lysa, the way he called meCat?

      how would you not know bruh

    48. “Was it news of Robb?”He hesitated. “Yes, my lady

      NOOO

    49. “There was a raven today, I saw. Has Jaime been taken again?” Orslain, gods forbid?

      just jaime? nothing else?

    50. “Dead.” His hand groped for hers. “You’llhave others ... sweet babes, and trueborn.”

      lysa...

    51. What would you say if you knew my crime, Father? shewondered. Would you have done as I did, if it were Lysa and me in thehands of our enemies? Or would you condemn me too, and call itmother’s madness?

      both tully sisters being traitors lmao

    52. He had seen Lord Hoster’s little Cat become ayoung woman, a great lord’s lady, mother to a king. And now he hasseen me become a traitor as well.

      nooo urghg

    53. “And you actually mean to keep it?” Jaime gave her his brightestsmile. “Now there’s a wonder.”

      totally different knights

    54. Pretty eyes, he thought, and calm.

      mhm thats right

    55. “I hope to blind my enemies with the sheen o my head. It’s workedwell enough for you.”

      lmao

    Annotators

    1. . Students need to know the lesson’s learning goals and what they need to do to achieve them.

      Students cannot succeed it is critical that a teacher establishes a clear learning goal for students to strive for. They also need to understand the steps to get there. If a teacher does this successfully, students will be set up for success in all they do.

    2. Embedded in formative assessment, is the need for students to be DOING something—talking about something, creating something—so that we can collect evidence of their learning. Learning through arts integration provides that opportunity

      I believe that students will do much better in a class when they are DOING something, as said in the article. When students are actively using their hands, brains, and all other senses, they will learn better. Arts integration is a great way to get kids moving.

    1. Serbian uses the latin alphabet (most of the time on typewriters) and letters unique to it are "žčćšđ" while Czech adds "" but upsidedown on other letters. Finally Polish can be identified by the 'Ł ł"

      Distinguishing some European keyboards on typewriters.

      via u/Cevkica at https://www.reddit.com/r/typewriters/comments/1eih25t/finally_got_a_letera_32/lg70tm0/

    1. attach(target = PocketCastsStarsExport, modules)

      Derp. This is the wrong way to do default parameters.

    2. PocketCastsStarsExport.UPDATE_ENDPOINT = ( `https://api.pocketcasts.com/sync/update_episode_star` )
    1. Smith-Corona Series 5 and 6 typewriters had a small piece of rubber around a portion of the escapement which can wear out or become damaged. This in turn causes the escapement to not work properly and cause the dogs to get jammed resulting in large movements of the carriage while typing or spacing.

      Joe Van Cleave calls it the "return silencer" and replaced his by tracing out the damaged piece on a sheet of 1/32" rubber and cutting it out as a replacement.

      Duane at Phoenix typewriter describes replacing it with rubber tubing (possibly something like heat shrink?) instead. See: https://hypothes.is/a/tG4BWk77Ee-jczsjoM8SzA

    2. I love that Joe is helping out with a local school's analog typewriter club.

    3. Typewriter Escapement Repair by [[Joe Van Cleave]]

    1. Summary of Computability Theory and Historical Development

      Introduction to Algorithms

      • "An algorithm is a sequence of instructions followed by a computer."
      • Historical context: Originally, "computer" referred to a person executing algorithms, not machines.

      Historical Context of Algorithms

      • Ancient origins: Algorithms date back to "Euclid's elements in classical Greece and to eponymously al-khwarizmi in 9th century Persia."
      • Formal definition: "A formal mathematical definition doesn't appear until the 20th century with proposals by Alonzo Church, Kurt Gödel, and Alan Turing."

      The Entscheidungsproblem and David Hilbert

      • Hilbert's goal: Create "an algorithm that given a statement in formal logic would determine if that statement was true or false."
      • Gödel's Incompleteness Theorem: Published in 1930, "any logic powerful enough to represent arithmetic could encode the following statement: this statement is not provable," undermining Hilbert's goal.

      Development of Computability Concepts

      • Need for formal definition: Essential to show that the Entscheidungsproblem is undecidable.
      • Church's lambda calculus (1932): "By 1936, he used it to show the Entscheidungsproblem is undecidable."
      • Gödel's general recursive functions: "Gödel proposed this as an alternative definition of computability."

      Alan Turing's Contribution

      • Turing machines: "Turing showed that if Turing machine was your definition of algorithm, the Entscheidungsproblem was undecidable."
      • Equivalence of definitions: Turing proved that "his definition was equivalent to Church's and Gödel's," establishing a comprehensive concept of computability.

      Propositions as Types

      • Genson's natural deduction: "Jensen in his PhD thesis wrote...natural deduction, the main form of logic we use today."
      • Introduction and elimination rules: Rules are presented in pairs; "the pairs cancel out," leading to simplified proofs.

      Church's Simply Typed Lambda Calculus

      • Definition: Introduced in 1940, combining functions and pairs.
      • Simplification: Proofs and evaluations are simplified, ensuring termination for well-typed programs.

      Curry-Howard Isomorphism

      • Core idea: "Propositions in logic correspond to types in a programming language," demonstrating a deep structural correspondence.
      • Extension to other logics: The idea applies broadly, including "dependent types," "polymorphic lambda calculus," and others.

      Practical Implications and Industry Adoption

      • Slow adoption: "Good ideas often take a very long time, 25 or 30 years to be adopted."
      • Practical applications: "Pretty much every functional language you can name has as its core the lambda calculus."

      Philosophical Implications

      • Discovery vs. invention: The equivalence of different definitions suggests that "you've discovered something."
      • Potential universality: "Lambda calculus would be more like the thing on the Left that's easy to decipher than the squiggles on the right."

      Conclusion

      • Deep insights: "Lambda calculus is not invented, it's discovered."
      • Broader implications: The structuring of information through computer science concepts "has to have implications everywhere."

      This summary captures the main points and significant details of the talk on computability theory, historical development, and the implications of these concepts.

    1. X24: Control signals to SSR (12 V)

      X24 has 8 terminal connections (4 x 12V dc outputs).

      Terminals 1, 3, 5, and 7 are +ve whilst terminals 2, 4, 6, and 8 are -ve.

      Therefore the 4 x 12 V dc output pairs are: 1 & 2 - 3 & 4 - 5 & 6 - 7 & 8.

      Where a single 4 pole SSR is installed (Some 6 tray machines) only the positive outputs 1,3,5,and 7 are used and terminal 2 is used as a common negative.

      Where muliple 2 pole SSR's are used (Most other Rational ovens) all 8 terminals are utilsed as 4 indivdual 12v dc outputs.

      Please go to trainin manual page 140 Chapter 18 for technical details and testing procedures of SSR relays.

    2. X29: Extension pcbs (A22 (4fold relays), A23 (energy optimization), A32 (SSR module for US/CAN) or A18 with iCPro XS

      X29 is an 8 pin terminal for the addition of optional pcb's.

      Icombi Pro and iCombi Classic can accomodate up to three Optional pcb's, whilst iCombiXS can accomodate only two additional pcb's.

      Please go to Training manual page 85 Chapter 8.3 for details of available options and how to install.

    3. X1: P1 Pressure senso

      The sole function of pressure sensor P1 is to continuously measure the differential pressure from the top motor drive shaft to the periphery of the top fan blade.

      In order to record accurate pressure readings P1 must be mounted horizontaly.

      P1 is powered with 12 Vdc from pcb A10, terminal X1, pins 1 & 3.

      The pressure readings are sampled via two tubes, one situated at the motor shaft, the other at the periphery of the fan blade.

      The difference between these negative pressures is measured and converted in the P1 pressure sensor to a dc voltage.

      When the fan wheel is stationary a dc voltage between 0.45 and 0.55 V is delivered to the A10 pcb terminal X1, pin 2.

      This voltage can be checked physically by appropriate meter and probes and also in:

      ICP Service Menu - Launcher for Humidity control.

      "See Training manual page 215 Chapter 25.4.5.Service for humidity control"

      and

      ICC Service menu - Diagnostic

      Training manula page 226 Chapter 26.4.1 Service chapter Diagnostic

      Differential Pressure across the fan varies with changes in fan motor speed and direction, cabinet air temperature and cabinet air humidity.

    4. X21: 230V power supply in

      The moment the appliance isolator is switched on 230 Volts is applied to terminal X21 on pcb A10 directly from L1 on the supply side of contactor K1.

      As X21 becomes under power, Pump PCB (A13) is immediately supplied with 230 V ac directly from A10 terminal X75

      Fuses A10 (F1) and A10 (F2) protect the conductors to all 230 Volt external components from damage due to component short circuit faults.

    5. X19: A31 Water distribution bloc

      Connection X19 has 6 pin terminals to supply 5 solenoid valves in the water distruibution block as required by the process selected. Each valve operates at 240V ac.

      Terminal Pin no 1 (White cable) drives solenoid valve Y2 (Control nozzle) and is ndicated with a small triangle printed onto the pcb.

      Terminal Pin no 2 (Yellow cable) drives solenoid valve Y1 (Water box / steam generator filling).

      Terminal Pin no 3 (Grey cable) drives solenoid valve Y3 (Moistening).

      Terminal Pin no 4 (Brown cable) drives solenoid valve Y14 (Cleaning box fill).

      Terminal Pin no 5 (Black cable) drives solenoid valve Y4 (Care box fill).

      Terminal Pin no 6 (Blue cable) is the Neutral to all solenoid valves in the block.

      As all connections to the pcb this connection is also coded (poke yoke principal) However during covid, some Combi Steamers were issued with uncoded connectors for X19.

      This raisese the possibility of the connector becoming out of algnment!, resulting in no solenoid valve functions or incorrect solenoid valve functions.

      Always check for the correct the alignment of this connector

      • Presenter discusses improvements in PowerPoint skills and the development of a new implementation of Idris.

        • "I've been working very hard on my PowerPoint skills recently this is a this is a kind of a show-and-tell session so I've been hiding away in my cupboard over the last few months working on a new implementation of address."
      • Curious about attendees' experience with dependently typed programming languages.

        • "Has anyone played with any dependently type of programming languages before just by way of show of hands?"
      • Overview of Idris improvements, focusing on type system advancements.

        • "Firstly definitely faster type checking...I don't get out much you know so them so I'm gonna show you a bit about the new interactive additive feature."
      • Emphasis on interactive editing and user-friendly type-driven development.

        • "It's all about the interactive editing it's all about the condo that the machine and the program of being in a conversation."
      • Introduction of quantitative type theory and its significance in Idris.

        • "The key new feature of the language though is that it's based on quantitative type theory."
      • Explanation of quantities in types: 0, 1, and many, and their runtime implications.

        • "0 means this is going to be a race at runtime and the type checker has told me that it's going to be raised at runtime 1 means I can use this exactly once at runtime and many is just back in the old world where we always used to be."
      • Demonstration of the use of quantities in practical examples like vectors.

        • "The basic idea is the lengths are encoded in the type...so if I'm writing an append function and I say the effector has n things and another vector has n things then the resulting vector has n plus M States."
      • Exploration of automated programming with interactive editing, including a magic trick analogy.

        • "Wouldn't it be nice if we get abstract away in the acts of programming so if we could just say you know keep case splitting and searching until you find an answer and hilariously that works quite well."
      • Advantages of having more information in types for program synthesis.

        • "The linearity gives more information to the type prototype directed synthesis."
      • Implementation of session types using linear and dependent types.

        • "With linearity and dependent types, you absolutely can do that and I think it's quite a nice way of writing concurrent programs."
      • Encouragement to contribute to Idris development on GitHub.

        • "Please come along I'd love to have your funky issues right so this isn't dependent type stock so by law I have to show you the vexes there's a reason I'm going to show you the vectors."
      • Final thoughts on interactive editing, efficiency, and community contribution.

        • "Interactive editing there's a lot more we can do with interactive editing really important that it's responsive so this is I want this to be the default mode in which people interact with the system if that's going to be the case it has to come back with the answer very quickly."
    1. problem-based learning (PBL)

      PBL can be used in special education by presenting students with real-world challenges that require them to collaborate, think critically, and apply their knowledge to develop practical solutions, thereby catering to diverse learning needs and fostering inclusive learning experiences.

    2. Examples of such tools are semantic and conceptual maps (Hwang et al. 2011, visualization tools (Huang, 2020), microworlds and simulations (Warren & Wakefield, 2013), and even emerging technologies such as robotics (Mikropoulos & Bellou, 2013).

      Semantic and conceptual maps, visualization tools, microworlds and simulations, and robotics are diverse educational technologies that enhance learning by offering visual, interactive, and immersive experiences. These tools aid in developing a deeper understanding of complex concepts and foster engagement through interactive simulations and emerging technologies​

    1. Was erwartet man auch wenn man Leute aus der dritten Welt herholt und ihnen unsere Kultur nicht vermittelt weil das ja diskriminierend wäre, natürlich leben die genau so weiter wie vorher

      ihnen unsere Kultur nicht vermittelt

      das war nie das ziel. das sind parasiten, die den sozialstaat kaputt machen, und die das volk mehr "sicherheit" fordern lassen. "integriert" (in die arbeitswelt) werden höchstens die kinder der migranten in 20 jahren.

    1. he two groups making most use of librarieswere “students and housewives” (women users outnumbered men by twoto one), but neither group was well served; and among employed men,6 percent of whites borrowed books, but only 0.1 percent of Black min-ers.18 These were dreadful numbers.

      reading as a leading indicator of cultural shift to help provide power to women and non-whites.

      Was the Great Books idea being pressed towards "men" a means of pushing back against this in some sense?

  2. ivanov-petrov.livejournal.com ivanov-petrov.livejournal.com
    1. 'Вообще надобно признаться, что восприятие и все, что от него зависит, необъяснимо на механических основаниях… Вообразим себе машину, устройство которой производит мысль, чувство и восприятие; ее можно представить в увеличенном виде, сохранив при этом те же пропорции, так что можно будет входить в нее, как в мельницу. Тогда, осматривая ее интерьер, мы не найдем ничего внутри нее, кроме частей, толкающих одна другую, и никогда не найдем чего-либо, чем бы можно было объяснить восприятие.'
    1. 记住要防止提交HTML表单的默认动作!

      在 HTML 表单中,当用户点击提交按钮时,浏览器会执行默认的提交动作,即刷新页面或发送表单数据到服务器。这通常会导致页面的完全刷新,以及丢失当前页面的状态和数据。

      在 React 中,我们通常使用 JavaScript 来处理表单的提交,而不是依赖于浏览器的默认提交行为。通过使用 event.preventDefault() 方法,我们可以阻止表单的默认提交行为,从而完全控制表单提交的过程,并避免页面刷新。

      阻止表单的默认提交行为有以下几个好处:

      1. 可以避免页面的刷新:如果页面刷新,会导致用户输入的数据丢失,用户体验不佳。

      2. 可以使用 JavaScript 处理表单数据:通过阻止默认提交行为,我们可以使用 JavaScript 来获取表单数据、进行验证、进行异步操作等。

      3. 可以实现单页面应用(SPA)的无刷新提交:在单页面应用中,我们希望在提交表单时只更新部分页面内容,而不是整个页面的刷新。通过阻止默认提交行为,我们可以使用 AJAX 或其他技术在不刷新页面的情况下提交表单,并更新页面的部分内容。

      总之,阻止表单的默认提交行为可以提供更好的用户体验,并使我们能够更灵活地处理表单数据。在 React 中,使用 event.preventDefault() 是一种常见的做法,以便我们可以完全控制表单的提交过程。

    1. Understanding the type of data collected is essential

      Understanding variables we have is quite important.

    2. Quantitative research can involve both quantitative and qualitative data

      ❓❓❓

    3. Quantitative research can involve both quantitative and qualitative data

      because both types of variables can be summarized and analysed numerically

    1. People do not always answer truthfully

      People may answer the questions even if they don't understand the questions.

    2. Question wording can be important.

      leading to making a big difference to the ansers that we get

    3. Do you avoid purchasing water in plastic bottles unless it is carbonated, unless the bottles are plastic but not necessarily if the lid is recyclable?

      Complicated to answer

    4. Do you drink water in plastic and/or glass bottles?

      Asking two questions ... better to ask two questions here

    5. Are you more concerned about Coagulase-negative Staphylococcus or Neisseria pharyngis in bottled water?

      Most people will give answers even if they actually don't know.

      ⇒ getting useless data

    6. Do you drink more water now?

      Ambiguous ... What do you mean? (more than yesterday? last week? WHEN?)

    7. do you support banning bottled water?

      Leading ... very obvious from the way the question is posed what answer everyone is wxpecting

    8. exhaustive

      EXCLUSIVE

    9. Ensure options are exhaustive

      Make sure that they're exhaustive → cover all options

    10. Ensure clarity

      clarity in our questions → we get the answers we seek

    11. Avoid problems with ethics

      Avoid people we're asking about a topic breaking laws, or revealing confidential or private information

    12. double-barrelled questions

      two things in one question

    13. Avoid asking the uninformed

      Ensure people we're asking understand of what we're taking about.

    14. Avoid leading questions

      respondents may be pushed in the direction

    15. questionnaire

      a set of questions for respondents to answer

    16. the types of analyses and software (including version) used

      What types of analysis is going to use?

      What software we use for those analyses?

    17. how data are collected from the individuals

      How we get the information from/about those indeviduals?

    18. how individuals are chosen from the population

      How we get the indeviduls from the population?

    19. repeatable

      everybody can understand exactly what was done, and how

    20. a pilot study

      a small test conducted before the actual data collection, not whole test

    21. pilot study

      a small test conducted before the actual data collection, not whole test

    22. to identify (and hence fix) possible problems

      This leads to better future studies.

    23. repeatable

      repeatable ⇒ enable others to replicate ⇒ can be ethical

    24. protocol

      a procedure documenting the details of the design and implementation of studies, and for data collection

    25. protocol

      a plan = should be established and documented before collecting the data → explains exactly how the data will be obtained, which will include operational definitions

      a procedure documenting the details of the design and implementation of studies, and for data collection

    1. Résumé de la vidéo [00:00:01][^1^][1] - [01:11:07][^2^][2]:

      Ce webinaire, coordonné par CultureCo et divers départements français, explore la coopération entre les acteurs culturels et ceux de l'éducation nationale. Il met en lumière les défis et les réussites des initiatives d'éducation artistique et culturelle, en particulier dans le département de la Mayenne.

      Points clés: + [00:00:01][^3^][3] Introduction et objectifs * Présentation des intervenants * Objectifs du webinaire * Importance des schémas départementaux + [00:02:31][^4^][4] État des lieux et défis * Impact limité des schémas sur la diversification * Importance de la coopération entre acteurs * Exemples de départements avancés + [00:03:27][^5^][5] Expérience de la Mayenne * Initiatives de Mayenne Culture * Nouvelles modalités de gouvernance * Structuration des coopérations + [00:04:55][^6^][6] Dispositifs spécifiques * Programme "Arts au collège" * Festival des Nuits de la Mayenne * Formation professionnelle pour enseignants artistiques + [00:05:34][^7^][7] Méthodologie et résultats * Études prospectives et diagnostics * Ateliers d'interconnaissance * Résultats et impacts des initiatives

    1. .

      Rererences

      [4] Farapti F, Maulia PH, Fadilla C, Yogiswara N, Rejeki PS, Miftahussurur M, et al. Community-level dietary intake of sodium, potassium, and sodium-to-potassium ratio as a global public health problem: systematic review and meta-analysis. F1000Research; 2022. https://f1000research.com/articles/11-953

      [40] Farapti F, Nadhiroh SR, Sayogo S, Mardiana N. Urinary and dietary sodium to potassium ratio as a useful marker for estimating blood pressure among older women in Indonesian Urban coastal areas. Mediterr J Nutr Metab 2017;10:113–22. http://www.scopus.com/inward/record.url?scp=85028772671&partnerID=8YFLogxK

    2. Farapti Farapti;  Sheila Amara Putri;  Annisaa Wulida Furqonia;  Purwo S. Rejeki;  Muhammad Miftahussurur

      Farapti Farapti1, Sheila Amara Putri1, Annisaa Wulida Furqonia1,2, Purwo Sri Rejeki3, Muhammad Miftahussurur45

      1Department of Nutrition, Faculty of Public Health, Universitas Airlangga

      2Government of Sobrah Village, Wungu District, Madiun Regency, Indonesia

      3Department of Physiology, Faculty of Medicine, Universitas Airlangga

      4Gastroentero-Hepatology Division, Department of Internal Medicine, Faculty of Medicine-Dr. Soetomo Teaching Hospital,

      5Institute of Tropical Disease, Universitas Airlangga

    1. “I’m also branching out to develop a typewriting service,” continues Leo. “I am currently typing the best man speech for someone. He’s getting it framed to use as a gift for the groom. I’ve also begun hiring typewriters out for weddings, to be used for guests to type notes for the bride and groom on the day.” What a genius idea.

      another example of people using typewriters for wedding mementos

    2. “There’s about 2,000 moving parts in a typewriter, but they’re really quite simple from a mechanical point of view.”

      Reasonable estimate it would seem. I haven't seen any others before.

    1. Operating expenses are covered by charging a fee of 10% on earnings in excess of the original investment and by charging an additional 5% withdrawal fee

      this is kind of high

    1. 領域

      「pane」を「領域」と約しているようですが、Windowsの用語として「ペイン」はあるようなので、そのまま片仮名にしていいと思います。

      https://learn.microsoft.com/ja-jp/windows/terminal/panes https://learn.microsoft.com/ja-jp/windows/apps/design/controls/two-pane-view

    2. ユーザーアカウント制御

      原文では、前の文"Open the installer and run it; "は末尾に ; (セミコロン)を使っていますが、ここでは接続詞のような意味で使っている気がします。

      参考: https://www.communicatable.com/2019/01/26/%E3%82%BB%E3%83%9F%E3%82%B3%E3%83%AD%E3%83%B3-%E3%81%AE%E8%A8%B3%E3%81%97%E6%96%B9/

      原文のニュアンスを活かすなら、文頭に「ここで、」や「この時、」をつけてはどうでしょう?

    3. トル

    4. アル

      ↓typo

      ある

    5. 「を」のほうがよさそうです。

    6. 雄逸

      「唯一」のtypo?

    7. 影響がある

      「影響がある」だとトラブルシューティングがやりにくくなるという意味に取れそうだと思いました。

      以下の原文の「inform」を「影響がある」と訳したのだと思いますが、「役立つ」としてはどうでしょう?

      because that can inform some of your troubleshooting work.

      目的語が人ではないinformは「役立つ」という意味になるという記事を見つけました。

      https://akio2017yamane.thick.jp/chuana-english/a-part-of-speech/verb/vocabulary-123/

      https://wordassist.jp/inform%E3%81%AE%E6%84%8F%E5%91%B3%E3%80%81%E4%BD%BF%E3%81%84%E6%96%B9/

    8. 段階を践む

      この書き方もあるのかもしれませんが、「段階を踏む」の方がよく見かける気がします。

    1. ome propose to perturb the data ineither the spatial domain of sensors [22, 12, 40],the frequency domain

      this is tragic. i should've been using this from the beginning

    2. [43].Although data augmentation is a well-established method in

      I should've been using this from the very beginning smh

    1. “I am honored to be the presumptive Democratic nominee,” Harris said during an online meeting of supporters that was broadcast live. Her ascent from running mate to party nominee caps a volatile few weeks in US politics that saw the party’s presumptive nominee, Joe Biden, end his bid for re-election following a disastrous debate performance that ignited a storm of calls from elected Democrats, donors and activists to step aside.

      Hellow

    1. The Orchard Keeper

      Could be classified as "Hillbilly Gothic"

    2. The Passenger” in itsunpublished form

      There is no material relating to STELLA MARIS in this collection.

    3. Notes to Researchers

      Columbia University houses the Random House Records which includes several folders relating to the publication of McCarthy's novels. https://findingaids.library.columbia.edu/ead/nnc-rb/ldpd_4079581

    4. Photocopy of corrected draft. No holograph corrections. 167 leaves.

      Patron note: There are some ALL THE PRETTY HORSES pages in this draft (box 97, folder 2)

    5. Holograph and printout pages in folder marked “Sunset - useable has been typedout.” 44 leaves

      Patron note: File contains a snippet from NO COUNTRY FOR OLD MEN (Box 95, folder 6)

    6. Typescript draft, unnumbered pages in folder marked “The Road – 1st draft.”Heavily corrected in pencil. 302 leaves.

      Patron note: A page of this draft is from SUNSET LIMITED (26th leaf, "10" in upper right corner). There are also 5 leaves of NO COUNTRY FOR OLD MEN (about halfway into the manuscript)

    7. Spiral-bound notebook titled “West” with post-it note on cover marked “Cities.”14 holograph pages and 1 piece of note paper laid-in.

      Patron note: Notes are likely related to BLOOD MERIDIAN

    8. Photocopy of corrected early draft typescript pages, no holograph corrections. 354leaves. Housed in 2 parts.

      Patron note: The draft is labeled THE CROSSING but it is ALL THE PRETTY HORSES (box 56, folders 3 & 4)

    1. Resistance is a habitual part of Thai’s work. Some resistance is as innocent as overwhelmed employees within the UC, who benefit from persistent reminders from Thai’s team. In working with vendors, Thai noted that vendors must also account for accessibility. If Thai experiences resistance from a vendor to accessibility measures, she may have to reference the vendor’s agreements with the UC or loop in the legal team. Thai emphasized that disability accommodations and accessibility are federal law

      great reminder and framing

    1. Case: Patient #16, Male

      DiseaseAssertion: UCD/OTCD

      FamilyInfo: N/A

      CasePresentingHPOs: Neonatal onset (HP:0003623), Hyperammonemia (HP:0001987)

      CaseHPOFreeText:

      CaseNOTHPOs:

      CaseNOTHPOFreeText:

      CasePreviousTesting: N/A

      Variant: NM_000531.6: c.77+2dupT

      ClinVarID: 567293

      CAID: CA891844248

      gnomAD:

    2. Case: Patient #50, Male

      DiseaseAssertion: UCD/OTCD

      FamilyInfo: N/A

      CasePresentingHPOs: Neonatal onset (HP:0003623), Hyperammonemia (HP:0001987)

      CaseHPOFreeText:

      CaseNOTHPOs:

      CaseNOTHPOFreeText:

      CasePreviousTesting: N/A

      Variant: NM_000531.6: c.174G>A (p.Trp58*)

      ClinVarID: 97127

      CAID: CA224490

      gnomAD:

    3. Case: Patient #85, Male

      DiseaseAssertion: UCD/OTCD

      FamilyInfo: N/A

      CasePresentingHPOs:

      CaseHPOFreeText:

      CaseNOTHPOs: Late Onset

      CaseNOTHPOFreeText: Milder phenotype

      CasePreviousTesting: N/A

      Variant: NM_000531.6: c.298+1G>T

      ClinVarID: 97160

      CAID: CA224544

      gnomAD:

    4. Case: Patient #32, Female

      DiseaseAssertion: UCD/OTCD

      FamilyInfo: N/A

      CasePresentingHPOs: N/A

      CaseHPOFreeText:

      CaseNOTHPOs:

      CaseNOTHPOFreeText:

      CasePreviousTesting: N/A

      Variant: NM_000531.6: c.140dup (p.(Asn47LysfsTer8))

      ClinVarID:

      CAID:

      gnomAD:

    5. Case: Patient #7, Female

      DiseaseAssertion: UCD/OTCD

      FamilyInfo: N/A

      CasePresentingHPOs: N/A

      CaseHPOFreeText:

      CaseNOTHPOs:

      CaseNOTHPOFreeText:

      CasePreviousTesting: N/A

      Variant: NM_000531.6: c.29_32del (p.Asn10fs)

      ClinVarID: 97157

      CAID: CA224540

      gnomAD:

      Gene Name: OTC (ornithine transcarbamylase)

    6. Case: Patient #15, Female

      DiseaseAssertion: UCD/OTCD

      FamilyInfo: N/A

      CasePresentingHPOs: N/A

      CaseHPOFreeText:

      CaseNOTHPOs:

      CaseNOTHPOFreeText:

      CasePreviousTesting:

      Variant: NM_000531.6: c.77+1G>A

      ClinVarID: 97313

      CAID: CA224773

      gnomAD:

    1. The magnitude of the raw difference is typically much larger than that of the posterior effects. The difference is likely caused by LD, in that the raw difference of a single mutation contains contributions from other linked mutations, which may inflate the estimates.

      Could you constrain this analysis to mutations that are in LE with other de-novo mutations to test this hypothesis?

    2. Here we employ a classical line-cross strategy with MA lines, to break down the linkage disequilibrium among the accumulated mutations. We then combine whole-genome sequencing with high-throughput competitive fitness assays to estimate the DFE of a set of 169 spontaneous mutations.

      I greatly enjoyed reading this paper. True experimental estimates of the DFE in MA studies are super valuable and provide a very interesting comparison for pop-gen based DFE methods as pointed out by the authors.

    3. Averaged over all RI(AI)Ls, accounting for variation among assay blocks and removing two outlying lines, the regression of W on number of mutations is not significantly different from 0 (slope = −0.0051, F1,509=1.83, P>0.17), although the trend suggests that mutations are deleterious, on average.

      Is there a chance that false negative mutations (i.e. incorrectly unobserved events in the MA lines) could contribute to this result?

    4. The simplest way to infer the mutational effect at a locus is to calculate the mean value of all lines with a mutant allele and all lines with an ancestral allele at that locus; the difference is the raw difference (uRAW) of the mutation at that locus. As a sanity check, we plotted the inferred Bayesian posterior effect against the raw difference; ideally, the correlation should be +1. The correlations were positive, but well below 1 in all three cases (Figure 4). The magnitude of the raw difference is typically much larger than that of the posterior effects. The difference is likely caused by LD, in that the raw difference of a single mutation contains contributions from other linked mutations, which may inflate the estimates.

      Two quick thoughts for further sanity checks. 1) Does this regression look any different for SNPs vs indels? 2) Do the individual mutation specific effects conform to expectations one might have based on the functional annotations available for these mutational events?

    1. I met several people whose institutions had little to no budget for such work.

      Or were these people just ignorant of the offerings that are already available?

    1. And reap his old reward: The blame of those ye better The hate of those ye guard

      Kipling captures the central paradox of imperialism. He acknowledges that despite the so-called "noble" intentions behind colonial efforts, the result is often resentment and blame from the very people being "civilized" or "improved." This part of the poem reveals a cynical view of imperialism, suggesting that despite the supposed benefits, the colonizers often face hostility and criticism. It’s a sobering reminder of the complexities and moral contradictions of empire-building, as well as the often unacknowledged negative consequences faced by the colonized.

    1. You tested the ASD and CHD and ASD-CHD genes to identify those that impact survival or proliferation of NPCs in either direction. I was curious about the breakdown of genes based on direction of phenotype (increased vs decreased proliferation, increased vs decreased survival). For example, knock down of cilia-promoting genes (or different ones) having a positive impact on proliferation given the need for centrosomal networks being required for both cell division and ciliogenesis (so these being somewhat mutually exclusive).

    1. fields of view surpassing 50 cm2

      This is indeed an impressive field of view, and the apparent SNR is impressive for ~10s exposures. More details on the laser power, diffuser, and detection optics would be appreciated!

    2. Pixel intensity profile along a line crossing the xiphoid cartilage on the mouse chest

      Could you annotate the reference line in the plot to make it more clear where the pixel intensities in (c) are extracted from.

    3. we acquired SWIR Raman images from intact mice illuminated from 785 nm, a commonly used wavelength in Raman imaging, to 1064 nm, a red-shifted wavelength that extends Raman scattering wavelengths beyond the limits of standard InGaAs-based detectors

      Could you provide information on the laser you used for this? It would be great if you could provide a more complete description of your experimental setup in a Methods section.

    1. A key result from our analyses is the high degree of plasticity in bacteria interactions depending on the environmental context.

      The plasticity of interactions is neatly demonstrated here. I wonder if the authors have any intuition about whether this plasticity could be controlled or reduced in more complex communities. In other words, would the presence of more species stabilize the interactions in the community regarding environmental changes?

    2. Exploring the constraints and cooperative potential as microbial communities grow presents a fascinating avenue for further investigation.

      Thank you for this very interesting and clearly presented work! Looking forward to seeing what comes next for more complex communities.

    3. In addition to the essential compounds, we randomly added a fixed number of environmental compounds that could be utilized by at least one of the bacteria (50 additional compounds for smaller environments; or 100 for larger, see Methods: Algorithm for generating environments).

      I am curious to know if some of these random environments are similar to known/relevant ecological niches, and which one? It could be informative to add this information somewhere if available.

    4. We found that the most common default interaction in both collections is neutral (see Fig. 1B), 49% in AGORA and 59% in CarveMe. Of the remaining interactions, we found that the CarveMe collection has more competitive interactions than AGORA and both collections have few cases of cooperation (2% AGORA and 0% CarveMe).

      Have the authors investigated whether the distribution of competition and cooperation interactions shows any correlation with the phylogenetic distance of the species?

    5. The joint environment was created by combining the default environments of the two bacteria such that both were guaranteed to grow.

      When both original environments shared similar compounds, did you add up the concentrations of these compounds, or did you keep the concentration from the original environment with the highest concentration?

    1. Protein expression and purification

      I am curious if there were differences in expression or yield between the different proteins. I could see that being important if the thought is to produce a bunch of this protein and use it to degrade PET.

    2. The position and orientation of the catalytic triad (D210, H242, and S265) overlaps perfectly with the catalytic triad in the parent enzymes

      This is interesting! Do the protein design methods you used specifically try to preserve the catalytically active parts of the protein or was this something that you assessed when picking proteins? If not, might that be useful to consider when selecting proteins to test? For example, maybe the proteins with negligible activity had a lot of differences in the triad. That seems like something you could catch before purifying and testing activity.

    3. Conclusions

      I'd love to see some discussion around your working hypothesis as it seems that you maybe disproved it? It might even be cool to have a bivariate plot with thermal stability on one axis and enzymatic activity on the other to see if there is a correlation. Additionally, because you tried 3 different methods to generate proteins and then evaluated them the same way, it might be useful to talk about which worked best, why that might be, pros/cons of the three methods, etc.

    4. data not shown

      Again, it would be interesting to see this data, even if you just put it in the supplement!

    5. data not shown

      This sounds like such a cool result, it would be great to be able to see the data.

    6. For the P06 and P08 variants, we did not set out to determine their melting temperature because of their negligible enzymatic activity

      It might still be useful to determine the Tm for these proteins to help with testing the working hypothesis that you discussed in the intro that proteins with higher stability have higher enzymatic activity.

    1. Taken together, these results suggest that ancestral Nrf and Keap1 genes were acquired in the LCA of metazoans and eumetazoans respectively (Figure 3A)

      Do search-based methods, e.g. BLAST or Foldseek, suggest an origin for these genes outside of metazoa? Are there other non-metazoan organisms that have this pair of genes present in their genomes?

    1. first 10 Principal Components (PCs)

      How many PCs can explain 95% of the variance? And how many features went into the PCA?

    2. host immunity is modulated to facilitate endosymbiosis

      It would be useful to show a schematic of the differences in aposymbiotic and symbiotic stony corals, kind of like a graphical abstract. The abstract was hard to follow without reading the details of the study, and it would be nice to see the overall findings in a visual way. This could get across the idea that neither the bacterial communities nor the proportion of immune cells differ between symbiotic states, but the gastrodermis I cells downregulate immune genes when algae is in close contact. That begs the question, will you follow up to determine what chemical cues from the algae are sensed by the gastrodermis cells to alter their gene expression?

    1. Immersing these materials in an LB medium also resulted in complete degradation

      Does this suggest that immersion in any liquid would induce degradation? I would like to understand if the biocomposites start to degrade in water, or even in high-humidity environments without suspension in liquids. I might be missing something about what these lipases need for activity, though.

    2. whereas the materials’ ability to elongate (Figure 6h) was slightly reduced upon addition of spores.

      I'm curious about applications and materials where this would matter. Are there plastics that don't need as much elongation?

    3. This result shows that while the recycled spores retain catalytic activities, they tend to be slower than the pristine ones.

      What could be contributing to reduced catalytic activity? It's interesting that activity is renewed after a vegetative cycle - do displayed lipases degrade over cycles?

    4. GPC trace of all PCL fragments before and after incubation with (b) TIED-LipA and (c) TIED-LipB.

      I'm not very familiar with analyzing GPC traces. There are red and blue boxes highlighting peaks in the data around elutions times of 3.5-4min, but I don't see descriptions of those highlight boxes anywhere. Are these peaks important? I assume they are because they decrease over incubation time.

    5. These TIED spores displaying recombinant enzymes exhibited robust catalytic activities, resilient in harsh conditions, and enabled recycling and complete renewal of catalytic activities through the cycle of germination and sporulation.

      This is a fascinating preprint, thank you! Creating a more resilient way to break down plastics--especially by creating biocomposite materials--seems like a broadly useful breakthrough.

      I'm curious about real-world application of this technology. Do you see either of the two processes described being more useful for manufacturers/processing facilities? Will it be easier to incorporate a spore suspension step, or is starting from a biocomposite material simpler?