752 Matching Annotations
  1. Last 7 days
  2. Apr 2021
    1. RRID:ZDB-GENO-140424-5

      DOI: 10.1016/j.devcel.2021.03.027

      Resource: (ZFIN Cat# ZDB-GENO-140424-5,RRID:ZFIN_ZDB-GENO-140424-5)

      Curator: @Naa003

      SciCrunch record: RRID:ZFIN_ZDB-GENO-140424-5


      What is this?

    2. RRID:ZDB-GENO-101201-5

      DOI: 10.1016/j.devcel.2021.03.027

      Resource: (ZFIN Cat# ZDB-GENO-101201-5,RRID:ZFIN_ZDB-GENO-101201-5)

      Curator: @Naa003

      SciCrunch record: RRID:ZFIN_ZDB-GENO-101201-5


      What is this?

  3. Mar 2021
    1. Results for individual PALB2 variants were normalized relative to WT-PALB2 and the p.Tyr551ter (p.Y551X) truncating variant on a 1:5 scale with the fold change in GFP-positive cells for WT set at 5.0 and fold change GFP-positive cells for p.Y551X set at 1.0. The p.L24S (c.71T>C), p.L35P (c.104T>C), p.I944N (c.2831T>A), and p.L1070P (c.3209T>C) variants and all protein-truncating frame-shift and deletion variants tested were deficient in HDR activity, with normalized fold change <2.0 (approximately 40% activity) (Fig. 1a).

      AssayResult: 4.5

      AssayResultAssertion: Normal

      StandardErrorMean: 0.23

    2. A total of 84 PALB2 patient-derived missense variants reported in ClinVar, COSMIC, and the PALB2 LOVD database were selected

      HGVS: NM_024675.3:c.109C>A p.(Arg37Ser)

    1. SUPPLEMENTARY DATA

      AssayResult: 86.49

      AssayResultAssertion: Not reported

      PValue: 0.3376

      Comment: Exact values reported in Table S3.

    2. To this end, 44 missense variants found in breast cancer patients were identified in the ClinVar database (https://www.ncbi.nlm.nih.gov/clinvar) and/or selected by literature curation based on their frequency of description or amino acid substitution position in the protein (Supplemental Table S1).

      HGVS: NM_024675.3:c.194C>T p.(Pro65Leu)

    1. Source Data

      AssayResult: 93.33

      AssayResultAssertion: Not reported

      ReplicateCount: 2

      StandardErrorMean: 11

      Comment: Exact values reported in “Source Data” file.

    2. Source Data

      AssayResult: 108.51

      AssayResultAssertion: Not reported

      ReplicateCount: 2

      StandardErrorMean: 17.71

      Comment: Exact values reported in “Source Data” file.

    3. Source Data

      AssayResult: 92.32

      AssayResultAssertion: Not reported

      ReplicateCount: 2

      StandardDeviation: 2.26

      StandardErrorMean: 1.6

      Comment: Exact values reported in “Source Data” file.

    4. We, therefore, analyzed the effect of 48 PALB2 VUS (Fig. 2a, blue) and one synthetic missense variant (p.A1025R) (Fig. 2a, purple)29 on PALB2 function in HR.

      HGVS: NM_024675.3:c.1222T>C p.(Y408H)

    1. Most Suspected Brugada Syndrome Variants Had (Partial) Loss of Function

      AssayResult: 0.6

      AssayResultAssertion: Abnormal

      ReplicateCount: 25

      StandardErrorMean: 0.4

      Comment: This variant had loss of function of peak current (<10% of wildtype), therefore it was considered abnormal (in vitro features consistent with Brugada Syndrome Type 1). (Personal communication: A. Glazer)

    2. we selected 73 previously unstudied variants: 63 suspected Brugada syndrome variants and 10 suspected benign variants

      HGVS: NM_198056.2:c.1099C>T p.(Arg367Cys)

    1. « Le règlement intérieur comporte un chapitre consacré à la discipline des élèves. Il reproduit l'échelle des sanctions prévues à l'article R. 511-13 et prévoit les modalités de mise en œuvre des mesures de prévention, de responsabilisation et d'accompagnement, notamment lorsqu'elles font suite à la réintégration d'un élève exclu temporairement pour des faits de violence.»
    2. Le règlement intérieur doit désormais prévoir les mesures de prévention, de responsabilisation et d’accompagnement pour les élèves ayant fait l’objet d’une exclusion temporaire (article R 421-5):«... prévoit les modalités de mise en œuvre des mesures de prévention, de responsabilisation et d'accompagnement, notamment lorsqu'elles font suite à la réintégration d'un élève exclu temporairement pour des faits de violence.»
  4. Feb 2021
    1. RRID:ZDB-ALT-170927-5

      DOI: 10.7554/eLife.54491

      Resource: (ZFIN Cat# ZDB-ALT-170927-5,RRID:ZFIN_ZDB-ALT-170927-5)

      Curator: @scibot

      SciCrunch record: RRID:ZFIN_ZDB-ALT-170927-5


      What is this?

    1. RRID:ZFIN_ZDB-ALT-160122-5

      DOI: 10.7554/eLife.55771

      Resource: (ZFIN Cat# ZDB-ALT-160122-5,RRID:ZFIN_ZDB-ALT-160122-5)

      Curator: @scibot

      SciCrunch record: RRID:ZFIN_ZDB-ALT-160122-5


      What is this?

    2. RRID:ZFIN_ZDB-ALT-140522-5

      DOI: 10.7554/eLife.55771

      Resource: (ZFIN Cat# ZDB-ALT-140522-5,RRID:ZFIN_ZDB-ALT-140522-5)

      Curator: @scibot

      SciCrunch record: RRID:ZFIN_ZDB-ALT-140522-5


      What is this?

    1. Supplemental material

      AssayResult: 101

      AssayResultAssertion: Normal

      Comment: See Table S3 for details

    2. Supplemental material

      AssayResult: 5.4

      AssayResultAssertion: Abnormal

      Comment: See Table S3 for details

    3. Supplemental material

      AssayResult: 82

      AssayResultAssertion: Normal

      Comment: See Table S2 for details

    4. Supplemental material

      AssayResult: 6.4

      AssayResultAssertion: Abnormal

      Comment: See Table S2 for details

    5. We analysed a total of 82 blood samples derived from 77 individuals (online supplemental table 3). These 77 individuals corresponded either to new index cases suspected to harbour a pathogenic TP53 variant or to relatives of index cases harbouring TP53 variants.

      HGVS: NM_000546.5:c.1010G>A p.(Arg337His)

    1. For Outbound Calls
    2. Mr./Mrs. Cardholder, please note that we’ll not be able to assist you if you have not entered your card information using the right prompts in our Automated Telephone System/IVR. Therefore, I am going to have to transfer you to the Automated Telephone System so you can enter your card information using the relevant prompts and, if needed, press the right option to talk to one of our customer service representatives.
  5. Jan 2021
    1. Klisnick

      The citation “Darmon et al.” has been changed to “Klisnick et al” as per reference list. Please check and confirm.

      ML: Klisnick is not the correct reference

    Tags

    Annotators

  6. Dec 2020
    1. Ainsi, les auteurs ont montré que Nao pouvait de ce fait participer aux thérapies visant à améliorer le déficit d'attention conjointe constaté chez les enfants atteints de troubles du spectre autistique. En revanche, il n'est absolument pas question de remplacer les thérapeutes humains, qui adaptent bien mieux leur comportement au cas qu'ils ont face à eux que la machine.

      L'introduction du paragraphe par ainsi nous emmène vers une conclusion et un renforcement d'argument de départ que Nao est fait pour améliorer le déficit d'attention conjointe chez l'autiste et pas pour être à la place du thérapeute dans un cadre de thérapie.

    2. Pour tester l'efficacité de leur protocole, les auteurs de cette étude ont comparé le succès de l'Homme et de la machine sur une douzaine d'enfants de 2 à 6 ans, dont la moitié souffrait d'autisme. Les participants du groupe témoin manifestaient davantage d'attention à l'expérimentateur humain que les autistes, d'après le temps de regard que chaque enfant consacrait à son interlocuteur. En revanche, les deux lots manifestaient autant d'intérêt au robot

      Une expérience faite sur deux groupes sujets au nombre de douze âgés de 2 à 6 ans dont la moitié souffrait d'autisme. le groupe témoin manifeste une attention à l'interlocuteur et au robot. le groupe autistes manifeste plus d'attention au robot qu'à l'interlocuteur. Ici, une comparaison de résultats entre deux groupes pour montrer le manque d'attention des autistes face aux humains et qu'ils sont plus attirés par le robot.

  7. Sep 2020
    1. ZDB-ALT-110215-5

      DOI: 10.1016/j.celrep.2020.108054

      Resource: ZFIN_ZDB-ALT-110215-5

      Curator: @Naa003

      SciCrunch record: RRID:ZFIN_ZDB-ALT-110215-5

      Curator comments: allele name: rw0143aTg Danio rerio ZFIN Cat# ZDB-ALT-110215-5


      What is this?

    1. and Gilgamesh [carried] the head of Humbaba.

      Short, but main conclusion.

    2. 'My friend, Humbaba who guards the Forest [of Cedar-] [finish him,] slay him, [do away with his power,] before [Enlil] the foremost hears what we do!

      Enkidu trying to encourage Gilgamesh to kill Humbaba.

    3. Do not listen, my [friend,] to Humbaba's words,

      warning from Enkidu to Gilgamesh.

    1. ZDB-ALT-080808-5

      DOI: 10.1016/j.devcel.2020.03.017

      Resource: (ZFIN Cat# ZDB-ALT-080808-5,RRID:ZFIN_ZDB-ALT-080808-5)

      Curator: @ethanbadger

      SciCrunch record: RRID:ZFIN_ZDB-ALT-080808-5


      What is this?

    2. ZDB-ALT-170224-5

      DOI: 10.1016/j.devcel.2020.03.017

      Resource: (ZFIN Cat# ZDB-ALT-170224-5,RRID:ZFIN_ZDB-ALT-170224-5)

      Curator: @ethanbadger

      SciCrunch record: RRID:ZFIN_ZDB-ALT-170224-5


      What is this?

  8. Jul 2020
  9. Jun 2020
    1. vous

      Pourquoi est ce que pour cette question il a fallu calculer a nouveau le rayon de la terre alors qu'elle était déjà donnée dans un document et que nous l'avons calculer dans la question 13 ? Et que les 3 valeurs ( valeur donnée dans le doc et dans les calculs ) ne sont pas les mêmes

  10. Apr 2020
    1. Quand on sait que parmi les figures les plus valorisées au sein des identités journalistiques, on trouve d’une part, le journaliste-reporter – toujours sur le terrain, en train de traquer l’événement là où il se passe – d’autre part, le journaliste-auteur, toujours en train d’écrire, on perçoit bien que le travail qui coince derrière un bureau un journaliste découpant et collant des morceaux de textes produits ailleurs, n’est pas exactement celui qui fait rêver.

      Met directement en confrontation l'investigation et le coté bureaucratique d'un journaliste.

    2. Des journalistes en train de jouer des ciseaux et de la colle ? Voilà qui flirte dangereusement avec le plagiat !

      Notifie explicitement la notion du plagiat qui n'est pas sans sanction ni conséquence qui découle d'une malhonnêteté intellectuelle

  11. Jan 2020
    1. Joint laxity
    2. Slender limbs
    3. carinatum
    4. Scoliosis
    5. Tall stature
    6. large ears
    7. Midface hypoplasia
    8. Open mouth appearance
    9. Long face
    10. aggressive behavior
    11. intellectual disability
    12. Developmental delay
    1. RRID:ZFIN_ZDB-ALT-160122-5

      DOI: 10.7554/eLife.42881

      Resource: (ZFIN Cat# ZDB-ALT-160122-5,RRID:ZFIN_ZDB-ALT-160122-5)

      Curator: @evieth

      SciCrunch record: RRID:ZFIN_ZDB-ALT-160122-5


      What is this?

    1. 5
    2. 5
    3. 5
    4. 5
    5. 5
    6. 5
    7. 5
    8. 5
    9. muscular hypotonia
    10. motor development
  12. Nov 2019
    1. Pacific Citizen, Vol. 45, No. 19 (November 8, 1957)

      This was in the legal topics section of the Densho Digital Repository. It speaks about racial hate groups and their rise in the west. This was after the internment ended and a few years after Pearl Harbor so this tells me there is still animosity and hate in the communities in regards to the Japanese.

    1. The myths then become a way to denounce Somalis as potential renewers by insisting on their status as guests, and specifically as recipients of charity, burdened by the gift of humanitarianism

      Somalis are what is keeping a struggling Lewiston alive.

    2. There can only be one dominant central culture: American.”

      Again racism and nationalism are still alive today.

    3. Reports in the paper of car accidents involving Somalis always provoke a slew of comments that they should not be allowed to drive at all.

      This again has to do with stereotypes regarding refugees. Americans treat immigrants as people who have never experienced driving or other luxuries. These type of thoughts provoke quite negative comments about refugees.

    4. The dol report also did not include the time Somalis donate to the city, through participating in the numerous focus groups of researchers and other organizations, giving (uncompensated) presentations to local organizations and schools, and vol-unteering in support of other city projects

      Some of these studies tend to leave out the good details behind something, it a way it gets society thinking about what THEY want them to think. In a way, this is pushing prejudice and racism.

    5. Less than 15 percent of the Somali population is on welfare. If you look at old Mainers, more of them are on welfare! We’re see-ing second- and even third-generation Mainers who are on welfare!

      Even more prejudice.

    6. When non-Somali clients whose tanf benefits are re-duced or denied because of household changes blame Somalis for their loss of benefits, he patiently explains that “everyone is getting exactly what they’re eligible for and Somalis don’t get any more than anyone else.” He is frustrated by the accusations that somehow Somali eligibility impacts the eligibility of other Mainers, and when I suggest it may reflect a perception of a zero-sum game—t he more they get, the less there is for me—he replies, “It’s not about the division of resources. It’s about prejudice.”

      It's hard to conceptualize this because our society thought they had moved past the discrimination when in reality nothing has changed when it comes to racism.

    7. They don’t know. No one’s ever explained it to them....[Our mu-seum visitors] didn’t have any idea they spent time in refugee camps and how horrible it was. They didn’t know about the war, about the loss, the horror....Viewers never realized how hard they had it in their country and why they had to leave. Genocide was never on their radar. Rape was never on their radar.

      Our society is so quick to judge and hate when someone knew comes into their community.

    8. When did maine become the welfare state to house and feed the worlds misfits.

      Why are people so upset about this?

    9. Areas that used to be decent to live in are now infested with them. Seriously, find twenty people in Lewiston who are glad they are here.

      Thats pretty racist

  13. Oct 2019
    1. None of that is possible with free but traditionally copyrighted content.

      I disagree again. Fair use in LMSs afford lots of pedagogical innovation, such as Hypothesis discussion of pdfs housed inside the shell and offered under fair use. I think the author is holding to tightly to his own 5-R formula, which is powerful but not omnipotent.

  14. Sep 2019
    1. systematic domination of women by men

      "systematic domination of women by men" the beside statement is varies according to person to person, that is the right each one but according to my perspective the idea is wrong because after a long period of time each girl will feel some loneliness. This isolation can be avoided if you have some to care you. No women in the could be independent but they can live independently only a certain period after they miss something in their life. Everyone will leave you but the one who love you will stick with your downs and ups. Your parents will pass you but your husband be with you until something has happen. Below you have five important benefits.

    1. “i want to live in the unknowing where everything is possible,”

      This sentence alludes to José Olivarez' mother, specifically his childhood with his mother where he doesn't know anything yet. Therefor, everything is possible. Aside from that, This also helps with understanding the content of the topic in which the three people are discussing.

    2. . i have my foot on the pedal

      This is meant to say that he is the person that takes charge of his life and no one else. Also, by not using capital letters at the beginning of the sentence(s), it allows it to seem more intimate and less professional, scripted.

    3. my mom hugs

      The purpose of the poem is to portray the life of a Mexican immigrant in The United States and the relationship with his mom

  15. Aug 2019
  16. Jul 2019
    1. Internet Reciprocal Teaching Promotes the Five CsCreativity: Students use divergent-thinking skills to generate their own questions and keywords for online searches. Their final projects require them to creatively express their own point of view. Communication: Students share what they learn as they work in small groups and with the whole class. They communicate with a wider audience by posting on a class blog. Collaboration: Students create collaborative knowledge through Internet inquiry and social interactions. They comment on one another's work using technologies such as VoiceThread and support one another through instant messaging. Critical Thinking: When using the Internet, students build the text they read, choosing which links to follow and which to ignore. The nonlinear nature of online reading helps support critical thinking. Students also learn to question the perspective and bias of online sources. Comprehension: Students learn important online reading skills, such as how to distinguish news articles from blog posts and editorials. They carefully read texts they encounter online to understand and evaluate different perspectives.

      5 Cs

    2. Internet Reciprocal Teaching Promotes the Five Cs

      5 C's of Internet Reciprocal Thinking: Creativity, Communication, Collaboration, Critical Thinking, Comprehension

    1. five phases:
      1. students collaborative with instructor to pick area of interest and work on a DQ to guide their research.
      2. students engage in OCI as the do research and use digital tools to make discoveries 3.Students use critical thinking to evaluate online info by analyzing credibility of their info. 4.Students synthesize what they learned/researched by combining info in multiple, multimodal sources.
      3. Students engage in online content construction by putting their research into their own words and choosing the best digital tool/text before sharing their answers.
    1. Despite the serious wrong done to us, the occupation of the port of Kiaochow was undertaken with the greatest care. We wish for the continuation of the friendship that has so long bound Germany with China and which so far has never been clouded.

      Germany wants to continue friendly relations while also being Asia's equal

    1. ake up the White Man’s burden — The savage wars of peace — Fill full the mouth of Famine And bid the sickness cease;

      Are they talking about the sacrifices the colony made?

    1. Evolutionary relationships of sorghum, rice and Arabidopsis with respect to Dofgene family
    2. Phylogenetic and motif analysis of sequenced Dof domains
    3. In silico characterization of sequenced Dof domains of cereal
    1. Treatment of L. donovani infected hamsters and isolation of mononuclear cells (lymph node cells)
  17. Jun 2019
    1. Increased Chemokine and Toll like receptor on T cells after vaccination in HBV positive newborns.
    2. Vaccination improved the Chemokine receptor CCR1, CCR3, CCR9 and Toll like receptor TLR2, TLR4 and TLR9 expression in HBsAgpositive newborns compared to healthy newborns.
    3. T cell frequencies(Post vaccination response)
    4. Post-vaccination immune responses in newborns