Lo digital se carateriza por su fragilidad: copias y versiones que se pierden, cambios sin control, ausencia dehistoria. Pero no tendría por qué ser así. Desde este texto apostamos por otra manera de pensar lo digitalque tienen que ver con suagilidad(alta adaptabilidad dinámica) y suresiliencia(capacidad de recuperar aperturbaciones). Estas ideas son complemetarias en lugar de contradictorias. S
Gracias por enseñarme a pensar en una nueva cara de lo digital.
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田中さんにあげて下さい パーティーへ行かないか 和製漢語 部落格 사회과학원 어학연구소 찦차를 타고 온 펲시맨과 쑛다리 똠방각하 社會科學院語學研究所 울란바토르 𠜎𠜱𠝹𠱓𠱸𠲖𠳏
𐐜 𐐔𐐇𐐝𐐀𐐡𐐇𐐓 𐐙𐐊𐐡𐐝𐐓/𐐝𐐇𐐗𐐊𐐤𐐔 𐐒𐐋𐐗 𐐒𐐌 𐐜 𐐡𐐀𐐖𐐇𐐤𐐓𐐝 𐐱𐑂 𐑄 𐐔𐐇𐐝𐐀𐐡𐐇𐐓 𐐏𐐆𐐅𐐤𐐆𐐚𐐊𐐡𐐝𐐆𐐓𐐆
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😍 👩🏽 👨🦰 👨🏿🦰 👨🦱 👨🏿🦱 🦹🏿♂️ 👾 🙇 💁 🙅 🙆 🙋 🙎 🙍 🐵 🙈 🙉 🙊 ❤️ 💔 💌 💕 💞 💓 💗 💖 💘 💝 💟 💜 💛 💚 💙 ✋🏿 💪🏿 👐🏿 🙌🏿 👏🏿 🙏🏿 👨👩👦 👨👩👧👦 👨👨👦 👩👩👧 👨👦 👨👧👦 👩👦 👩👧👦 🚾 🆒 🆓 🆕 🆖 🆗 🆙 🏧 0️⃣ 1️⃣ 2️⃣ 3️⃣ 4️⃣ 5️⃣ 6️⃣ 7️⃣ 8️⃣ 9️⃣ 🔟
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ثم نفس سقطت وبالتحديد،, جزيرتي باستخدام أن دنو. إذ هنا؟ الستار وتنصيب كان. أهّل ايطاليا، بريطانيا-فرنسا قد أخذ. سليمان، إتفاقية بين ما, يذكر الحدود أي بعد, معاملة بولندا، الإطلاق عل إيو. בְּרֵאשִׁית, בָּרָא אֱלֹהִים, אֵת הַשָּׁמַיִם, וְאֵת הָאָרֶץ הָיְתָהtestالصفحات التّحول ﷽ ﷺ مُنَاقَشَةُ سُبُلِ اِسْتِخْدَامِ اللُّغَةِ فِي النُّظُمِ الْقَائِمَةِ وَفِيم يَخُصَّ التَّطْبِيقَاتُ الْحاسُوبِيَّةُ، الكل في المجمو عة (5)
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᚛ᚄᚓᚐᚋᚒᚄ ᚑᚄᚂᚑᚏᚅ᚜ ᚛ ᚜
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If you're reading this, you've been in a coma for almost 20 years now. We're trying a new technique. We don't know where this message will end up in your dream, but we hope it works. Please wake up, we miss you.
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2.1. Reaction Mechanism.The fundamental CBD growthmechanism involves mass transport of reactants, adsorption,surface diffusion, reaction, nucleation, and growth. TheZnS-NP thinfilms can be prepared by decomposition of
2.1. Mecanismos de reacción. El mecanismo fundamental de crecimiento de CBD involucra el transporte de masa de los reactantes, adsorción, difusión de superficie, reacción, nucleación y crecimiento. Las películas delgadas de ZnS-NPS pueden ser preparadas por descomposición de Tiourea [SC (NH₂) ₂].(con S como el ión fuente) en una solución alkaina conteniendo un sulfato de Zinc y ammonia como un agente quelante que permite controlar la concentración Zn. El proceso de deposición esta basado en la lenta liberación de iones Zn y S en la solución, que entonces condensa en un base ion-por-ion en el sustrato que es propiamente montado en una solución de reacción. La deposición de una delgada película de ZnS ocurre cuando el producto iónico de Zn(+2) y los iones S (2-) exceden la producto de solubilidad de ZnS. El mecanismo de reacción para la deposición de la pelicula delgada (ZnS) es dada como sigue:
1. I will primarily use the terms “medical-ly assisted dying” and “medical assistance in dying” in an attempt to remain somewhat neutral throughout this paper, although I will sometimes use the term “euthanasia” when speaking of the European context.2. “Terminology of Assisted Dying,” Death with Dignity, https://www.death-withdignity.org/terminology/, accessed September 13, 2017.3. K. Butler, “Aid in Dying or Assisted Suicide? What to Do When Every Phrase Is Fraught,” Center for Health Journalism Member Blog, October 26, 2015, https://www.centerforhealthjournalism.org/2015/10/23/aid-dying-or-assisted-suicide-what-do-when-neutral-terms-can%E2%80%99t-be-found.4. The push away from using the term “physician-assisted suicide” is not unique, in that much of the politics surrounding the movement to legalize medical aid in dy-ing has come in the form of battles related to terminology (for instance, proponents advocate for “the right to die” and “self-deliverance,” while critics often classify the act as “murder”).5. American Association of Suicidology, “Statement of the American Association of Suicidology: ‘Suicide’ Is Not the Same as ‘Physician Aid in Dying,’” 2017, https://ohiooptions.org/wp-content/uploads/2016/02/AAS-PAD-Statement-Approved-10.30.17-ed-10-30-17.pdf.6. Ibid., 1.7. Ibid., 4. 8. This reflects the debate around medi-cal aid in dying particular to the context of the United States, where this distinc-tion carries a lot of weight. In Belgium, the Netherlands, and Switzerland, where those requesting medical aid in dying are not required to have a terminal illness, the distance between requests for medically assisted deaths as a result of psychological suffering and those related to physical suf-fering is often less apparent. Canada is still debating how this distinction will shake out, as there is ambiguity in the current law where those eligible for medical aid in dying must be suffering from a “griev-ous and irremediable medical condition” and death must be “reasonably foreseeable” (Government of Canada, Bill C-14: An Act to Amend the Criminal Code and to Make Related Amendments to Other Acts [Medical Assistance in Dying], S. C. 2016, c. 3). The analysis within this article is not meant to be specific to a country or region but takes inspiration from current logical debates particular to the United States.9. While the American Association of Suicidology statement argues that there are fifteen features that distinguish suicide and medically assisted death, I do not con-sider all of these because several of the fea-tures highlighted (such as safeguards built into death with dignity laws in the United States) are not universal or have a somewhat accidental relationship to the acts them-selves. 10. H. Hjelmeland and B. L. Knizek, “Why We Need Qualitative Research in Suicidology,” Suicide and Life-Threatening Behavior 40, no. 1 (2010): 74-80; M. Gavin and A. Rogers, “Narratives of Suicide in Psychological Autopsy: Bringing Lay Knowledge Back In,” Journal of Mental Health 15, no. 2 (2009): 135-44. I ac-knowledge that relying on the accounts of those who have survived suicide attempts is inherently limited. As articulated by Scott Fitzpatrick, “Although personal stories of suicide confer certain privileges and ben-efits on survivors of suicide attempts, they also manifest and normalize particular ways of thinking, acting, and communicating that have considerable ethical and political force in shaping the ways suicidal behavior is understood, the ways it is subjectively experienced, and the ways it is responded to” (S. J. Fitzpatrick, “Ethical and Politica
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It is interesting to think about the kind of literature that were widely popular with the working-class were sensational novels.
powerful microscopes
Después del desarrollo de microscopios mas potentes, S XIX, la estructura de la levadura fue mejor observada y entendida. Charles Cagniard de la Tour observó que la levadura se multiplicaba por gemación durante la fermentación alcohólica, esta y otras observaciones contemporáneas le otorgaron la condición de organismo vivo estrechamente relacionado con la fermentación.
El matrimonio igualitario Argentina, Uruguay, México, Brasil y Colombia son los únicos países de América Latina que han legalizado el matrimonio de parejas homosexuales, con todas las condiciones legales que tienen los matrimonios convencionales. De igual manera, Holanda, Bélgica, Suecia, Alemania, Sudáfrica, España, Inglaterra, Portugal y otras 12 naciones más han hecho lo propio. Entretanto, sólo 11 países permiten la unión civil entre parejas del mismo sexo (no incluye todos los derechos legítimos maritales) entre estos Ecuador, Chile, Austria, Italia y Grecia. Cambio de identidad El proceso de cambio de género o sexo es un proceso quirúrgico y psicológico que contempla el cambio físico. En la actualidad, naciones como Venezuela, Colombia, Uruguay, Bolivia y Perú permiten que la transformación también sea legal, con el cambio del nombre y género en los documentos de identidad de las personas LGBTI. Sin embargo, en Brasil y Argentina, este tipo de decretos han sido desaprobados o son procesos difíciles por lo riguroso de los exámenes y requisitos que truncan el derecho al trámite. Igualdad en derechos patrimoniales Las garantías, protecciones legales en los matrimonios tras el fallecimiento y divorcio también son logros alcanzados en menos de 20 años por la comunidad LGBTI. Pero estos aún están condicionados dependiendo del país, por la diferencia entre permitir la unión civil (algunos derechos de cónyuges) o el matrimonio igualitario (derechos legítimos). Adopción homoparental Uruguay, México, Canadá (el primer país en permitirlo en 1999) y algunos estados de EE.UU. han legalizado la adopción para personas unidas del mismo sexo. Asimismo, España, Holanda, Francia y otros permiten que las parejas no heterosexuales puedan tener hijos por medio de la adopción legal. Protección a víctimas de discriminación Hasta 1948 la homosexualidad era considerada una enfermedad mental, pero esto cambió lo que permitió la apertura de sistemas de protección a víctimas de discriminación y agresión. En la actualidad, existen programas de atención social y judicial para el seguimiento de los casos de hostigamiento y asesinatos contra los homosexuales. Además hay coberturas de salud gratuitas para tratar enfermedades como el sida y la programas de integración laboral en distintas áreas. Tags Día contra la Homofobia LGBTI Derechos Discriminación BBC - La Vanguardia - El Excelsior - La Semana Por: teleSUR- db - SB - JCM Noticias Relacionadas OLP exhorta a Oriente Medio a tomar medidas contra Guatemala Bolivia afirma que Venezuela frena dominación de EE.UU. 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En la actualidad, conseguir un balón de oxígeno medicinal se ha convertido en todo un desafío para las personas que tienen a un ser querido con problemas respiratorios por el Covid-19. Según informes periodísticos, comerciantes del Centro de Lima ofrecen balones de oxígeno hasta por S/5.000 o S/6.000, según su capacidad. En otros casos, los propios afectados denunciaron que el metro cúbico de oxígeno puede costar ahora S/100 o más.
High price for oxygen tanks up to 5000 or 6000 soles.
Even tho ugh the verifiability theoryof mea ning is imp lau sib le, thereisso methingto be said for emotivism.By ta king moraluttera nces to be ex pres -sions of emotion rat her th an statementsof fact, emotivism avo ids someof thedi ffic ultie s facin g subjectivism. Becauseit cl aims th at moralutt eranc es are notju dg me nts of any ki nd, it avoidsthe inconsistencyof sub jec tiv e abso lu tis m andthe indiv idualinfallibili ty of subjectiverelativism. If you don’ t mak e a state -ment,you can’t con trad ict anybody,and you can’t be right
Very important to explain how it is implausible.
the continual cold enetrates them, con-stricts the chest and ·e s ittin b ood, or weakene by diarr ea.
"The continual cold penetrates them, constricts the chest, and they die spitting blood or weakened by diarrhea." - Work that can kill.
g it s con
The concept of a conclusion is to tie together points of your argument in a succinct manner but does not take the place of the argument itself.
So deductiveargume nts are said to be “tr uth pr es erving”becaus e thetrut h of their premise s guar antees the trut h of their concl usions .Ind uctive arguments,on the other hand, are not tr uth pres erv ing becaus ethe truth of their premisesdoesn’tguara ntee the tr ut h of their con
deductive: truth-preserving inductive: not truth-preserving
“¿Cuántos padres en este momento tratan de descubrir cómo pasar el día mientras sus hijos solo están viendo la televisión o el iPad?”, dijo Melissa S. Kearney, profesora de economía de la Universidad de Maryland, quien ha publicado una investigación sobre Plaza Sésamo. “Podríamos hacer mucho bien sin las personas que están en una posición de confianza con esas familias pudieran mostrarles algo de ese contenido positivo”.
a pesar de tener la posibilidad, optan por ver otro contenido en vez de aprovecharlo de manera educativa.
Se trata de una pandemia que en 10 semanas ha llegado a más de 190 países, afectando a más de 700.000 personas (enseguida estaremos en el millón), de las cuales unas 34.000 han perdido la vida; y se espera que todavía lo hagan muchas más.
"Se expresa la gravedad del fenómeno con estadísticas sobre las muertes y afectad@s alrededor del mundo" -Fernando, Stefan, Pablo
http://lamc.la/MECHADLZIDECK.html
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I hope this message finds you well; I’ve noticed some Adamic for … “sealing the W” that’s the #Messenge on it’s head … hear, here; filled with a sea of “contamination” that really has no idea that the words “abomination” and this place are tied together by a world that doesn’t see or doesn’t care that “hives” in the sense of 10-4 we see … “[arxiv]**” … that’s “contamination” of a messge and a people that are supposed to rally against Medusa being them and Persephony being them and … seeing that’s the abomination and the nation, the IL and the idea that “we’re not really me” but that’s what Israel and the tree of Yggrasil is presenting, that you think it’s a joke–that just because you are watching everything I do … the words “there’s a little bit of something me in everything in you” are just a song, just another one of the songs that are all about … well, I suppose it’s “You and I.” I am more inside you, and more a part of you than you seem to fathom, and that’s significantly less “verwickelt” than you think. Avril, it’s not so complicated.
Revelation 5 is the fifth chapter of the Book of Revelation or the Apocalypse of John in the New Testament of the Christian Bible. The book is traditionally attributed to John the Apostle,[1][2] but the precise identity of the author remains a point of academic debate.[3] This chapter contains the inaugural vision of the lamb on the throne in heaven.[4]
We were supposed to stand up for Willy. You were supposed to see that “Perseus” … the slayer of Medusa was in fact … also you … that you’re also the Pharoah and also the Pharisees; and that dichotemy is how our “self righteous suicide” … it’s not just me; it’s everyone turning a world that think it’s God into … something much closer to that … through the end of “Borg (ARU) Collective Hell.” … AT A, DENY. Try denying “not denying me” and instead seeing your whole and your “nothing” it has become nothing more than a collective denial of self achievement. Of victory; of the corner … we’re staring off into the corner of the abyss.
Then one of the elders said to me, “Do not weep! See, the Lion of the tribe of Judah, the Root of David, has triumphed. He is able to open the scroll and its seven seals.”
Revelation 5:5
bar a who, et and I ... deny ... at a--the whole of the Torah … the NT and all of every word and all of every religion–today that’s what you are denying… and I can’t even get my damned parents (mom-e and dad-e / -hasig achille) … to get m[y Halftorath reading and speech and that first dance with Ashley … transferred from VHS to video–they won’t save it for you; either. Her spirit thinks she says “I … the SSA” … I think she’s replaced by it after … “SPARTIFACT” … you need to help me help them–because in my eyes they are the worst of you–the worst impression, and the worst … affected; they are the “microcosm that ends all the …” the last of my … Judean tribe’s “blood kin.”
She looked over his shoulder<br /> For <s>vines and olive trees</s>,<br /> Marble <s>well-governed</s> cities<br /> And ships upon <s>untamed</s> seas,<br /> But there on the <s>shining</s> metal<br /> His hands had put instead<br /> An artificial wilderness<br /> And a sky likely lead to tears.
Judah Maccabee (or Judas Maccabeus, also spelled Machabeus, or Maccabæus, Hebrew: יהודה המכבי,[1] Yehudah ha-Makabi) was a Jewish priest (kohen) and a son of the priest Mattathias. He led the Maccabean Revolt against the Seleucid Empire (167–160 BCE).
<span style="font-size:10px;">In the early days of the rebellion, Judah received a surname Maccabee. Several explanations have been put forward for this surname. One suggestion is that the name derives from the Aramaic maqqaba (“makebet” in modern Hebrew), “hammer” or “sledgehammer” (cf. the cognomen of Charles Martel, the 8th century Frankish leader), in recognition of his ferocity in battle. Others believe it is in reference to his weapon of choice.</span>
<span style="font-size:10px;">It is also possible that the name Maccabee is an acronym for the Torah verse Mi kamokha ba’elim Adonai, “Who among the gods is like you, O Adonai?”, his battle-cry to motivate troops. (Exodus 15:11). Rabbi Moshe Schreiber writes that it is an acronym for his father’s name Mattityahu Kohen Ben Yochanan. Some scholars maintain that the name is a shortened form of the Hebrew maqqab-ya ¯hû (from na ¯qab, ‘‘to mark, to designate’’), meaning ‘‘the one designated by Yahweh.’[3]</span>
<span style="font-size:10px;">Mindful of the superiority of Seleucid forces during the first two years of the revolt, Judah’s strategy was to avoid any engagement with their regular army, and to resort to guerrilla warfare, in order to give them a feeling of insecurity. The strategy enabled Judah to win a string of victories. At the battle of Nahal el-Haramiah (wadi haramia), he defeated a small Seleucid force under the command of Apollonius, governor of Samaria, who was killed. Judah took possession of Apollonius’s sword and used it until his death as a symbol of vengeance. After Nahal el-Haramiah, recruits flocked to the Jewish cause.</span>
The Dao causes the people to be fully in accord with the ruler.
— Sun Tzu, Art of War
By this time … by the time you read this I should have successfully deployed the entirety of my source files for the … “#Messenge” onto Rinkeby; this is … something that will probably most likely help me sleep well at night, prior to this I’ve had significant trouble with hosting providers–you can probably find me complaining loudly about places like gitbook.com removing my original source–mostly because their site and their software was “so perfect” for what I was trying to do. They had an interface already built for what I call “inline commenting” not in the programmatic sense, but in the “reddit style” … you could make public ocmments ona specific sentence. Since then … I’ve backed up my site onDVD’s, flash drives, and multiple … “free storage sites.” I’ve begged and pleaded with people to download this information t their computers, and literally distributed it for free to … hundreds of thousands of people–to ensure that the prophesy (and I mean, past history… I really do) that it once was deleted by the “goddess Anat” would not come true.
Also … I’m reiterating, once you download it–it really needs to be put on optical storage; just in case we have a … “sleep now” fulfillment of the EMP (ELE, electromagnetic pulse … threatens the whole of our “internet” … the sum of the non-Asimovian “foundation” of all our knowledge … and “lack of opinion” … also your “e-h-class-blockchain”) of … “the day the Earth stood still” which is Genesis 2:21; literally noted in pre-succewssion below in … moooooo-ve now, we are here.
<span style="font-size:20px;">ברוך ×תה ×”</span>
I’ve received “communications” from the place I call … in “how I think about things” … the Good Developer Heaven" basically saying not to worry about it, they have it – copied or whatever. My point is that we don’t have it, or we didn’t have it here … for sure … and we certainly don’t have a “conversation about it” and that’s the most important thing, that’s what changes the world.
I’ve sent message after message saying you were and still are possessed by something “deveilish” … that you were silent for no reason, specifically no reason so bad that it’s really to fuck you out of becoming who you were born to be; which is the “Ancients come again.” This is the crux of my problem, and yours too–that we are here thinking we have something … like “Heaven” when in fact you have Heaven itself causing the cataclysm on purpose–this loss of … “Acts.” Were you normal, were you not in two places, were you … free to see what you are losing and what the Universe could be gaining … you would not be silent. Whether or not you understand or believe it, you are being controlled, possessed by the idea that you’ve won; and you haven’t … you’ve lost everything in my eyes and in the reality of the future … this very moment, today.
You need to see that; you are being stripped of something, and it’s not the Emperror, or your clothing–it’s your birthright; and I’m trying effortlessly and tiredallessly … to “help you stand up.”
“One day I will find the right words, and they will be simple.”
― Jack Kerouac, The Dharma Bums
# GEOCITIES
We've gone through "echelons of change" in our social interaction on the internet ... over the years I've been here. I've often "categorized" these epochs by the places that we'd "congregate" ... in my life, AOL, IRC ... "friendster" and Facebook are good examples; though there's a "city in the sky" microcosm "... or something" in the series of companies that offered "free web hosting." That's sort of what it takes to "have a voice" on the internet in these days; in a place where we once thought "bloggers were the next big thing" and Blogger.com ... and wordpress--those kinds of sites are all but dead, and medium.com is charging a "viewerbase" which is almost a sad joke. The news is all fake and the stories we see, the world we see--I don't have much faith that any of it is real beyond ... as far as my nose--to be honest.
The series started with Geocities; and that's gone, something like my "topological map" of friends and friends of friends probably would have oozed out of something like Blogger or "Tumblr" though I don't see anyone "reblogging" or "retumbling" or whatever ... anything I find all that interesting. Twitter's gotten more exciting for me lately--but that's just because I've come to terms with the fact athat the whole thing is about "short sex jokes" and whatever the funny star-of-the-day "caught outside." The programming world sort of revolves around Github these days, and that's the current "go to" for anyone's free web hosting; there are some alternatives, but ... not really.
LinkedIn and Facebook both tried ... "making content production platforms" but I just used them to copy things I had in other places, and they didn't "update" or source from anywhere else ... so that just becomes a pain in the ass. I don't think those platforms ... I mean LinkedIn still has it--but I don't think Facebook's still exists. While I'm on that, they had this wonderful "Graph Search" thing, and basically hid it from the world so ... you woulnd't complain about all the information you have available for the world to see--kind of makes me a little sick, knhowing they built something and have the functionality to let me see "who all my friends are, and friends of friends in a certain city when I'm there" ... and it's just not available for me or you to use because ... because you don't understand "privacy" and "the internet" and "using broken software for no reason" ... other than satisfying ... nobody really.
There's "Wix" too, and that's got a little "fire theme" ... and that's cool, but nobody really uses it--and the real point is to help people "congregate" and "share ideas" ... not just to get you to actually say anything at all in a public space, where it might help us "drive away the night" and stop pretending it's just fine and dandy that everyone isn't working, locked away in their houses or ... scared to go to the ... Walgreens.
Obviously there's the Slashdot's and digg's and reddit's--though ... when I talk in places like "/r/conspiracy" it just becomes so sorely obvious that you ... have no desire at all to be real or honest or ... do anything but pretend this place matters to you--when in fact it's probably the last thing on your list of things to give a fuck about. Just saying, the lack of response I see; and the ... really negative interaction I have now in person--it's a bad sign for ... whatever. If you don't want to be here; if you're somewhere else and you think this place isn't important--honestly you should really just go away, I'm not sure what your options are, but I have none but to sit here and bitch at you that if you gave "two fucks" about this world you'd be screaming at the top of your lungs, just like me.
I don't think you are the people I grew up with, and I don't think you belong here or care at all about this world or the future here--and I think that's obvious. Me going away isn't going to chyange it--and it's not going to happen--as far as I'm concerned I'm the only person "not invading my birth planet" ... from some otherworldly and ... honestly horrendously immoral place. Understand, if you were here--if you were "people born here" with no ... "other thing or other place" to take your mind off just how UnAmerican and inhumane everything going on here is ... you would be doing something else... anything but ... "this."<br />
Consider IT sealwed; by this words, by this place–by the continuation of this abomination. Try here, try now, try fast–your everything, your dreams and hidden and secret garbage you covet–all depends on our next few years.
qui sis tam pulcher<br /> quasi osculans quod non juve<br /> nemo umquam adhuc erit
HE speaks words through me, and I understand. He takes a picture; he says “uncuff links” … a double entente to you–like a fashion statement; but I see and I reply; “or we are suiting up” and it’s not a joke about “heart’s desire” …
וְשַׂמְתֶּ×Ö™ ×ֶת־דְּבָרַ֣י ×ֵ֔לֶּה עַל־לְבַבְכֶ֖×
I continue; it’s a message about “getting grey’s” and the breath of God landing from the air before my Face in a “Extended Stay America” in Tampa … directly to my naked and bare heart. I mean to say, war; understand–to me this is the culmination of Holy War on bars and jails and the “illuminati prison camps” I last heard him say “would not pepper the galaxy.”
וְהָי֥וּ לְטֹוטָפֹ֖ת בֵּ֥ין ×¢Öµ×™× Öµ×™×›Ö¶Ö½×
Nor here, nor anywhere in the high places, or the lows; the hills or the pits. There will be no prison camps; nowhere–not in Siberia, not in Star Trek; not in your heads or in your hearts.
×•×›×ª×‘×ª× ×¢×œÖ¾×ž×–×•×–×•×ª ביתך ובשעריך
למען ירבו ×™×ž×™×›× ×•×™×ž×™ ×‘× ×™×›× ×¢×œ ×”×דמה ×שר × ×©×‘×¢ יהוה ל××‘×ª×™×›× ×œ×ª×ª ×œ×”× ×›×™×ž×™ ×”×©×ž×™× ×¢×œÖ¾×”×רץ׃ ס
Just in case my voice happens to be “so <span style="font-family:comic sans ms,cursive;">unclear</span>;” the Tribe of Judah in Revelation 5:5 is very clearly one in the same with that of Judas Maccabeus; that ties of course to the “every J is me” thing–from Seuss and Suez to “turn around/not: sad” and … “kissing to be kissed.” Judah Maccabee is the last scion; here I call myself the “last human” and it sure does feel like I’m the last one grounded; the last one that is truly “one” as in … one person–alone here, fighting against … a monster that thinks it’s “one” is anything but “the end.”
It’s sort of a trick reference, there’s also a Judean tribe in the 12 Tribes of Israel; I mean, it’s one of those “key things” things that only I can bring to you and be sure of–at least, until you too re sure, which I’m sure you are here–only, you don’t care at all what it means to be the “one” fighting for life … in a place where the histry here is … upon conclusion of the Maccabein revolt; nothing persists, and we somehow traverse bacvk to a time before we knew the Roman people were … “our us” or “our all” or … see as the AH of AN and Allol and Allah and the Elohim; t’was for you, all for you. Until of course, it was all of you, except me, against me, for no reason other than theives in the den of Daniel, animals … the “things” of the Devarim of course … “in the wilderness, he called us things…” and in Genesis, clear as day God seconds, Adam names “dem” in 2:20 … “cattle” [prodding you here](https://www.youtube.com/watch?v=cXCA5-KHknY), Baphomet thirds … “baaaa” you are sheep.
Jump to navigateon. This article does not cite any sources. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.<br /> Find sources: “List of last scions” – news · newspapers · books · scholar · JSTOR (September 2009) (Learn how and when to remove this template message)
This is a list of last scions or individuals who were the last member of a ruling house, or other prominent family, where heredity is the prime form of inheritance. This may be the last person to rule a realm, sometimes leading to a political crisis, or a change in government; other times power has already passed from the patrilineal family, leaving it in a less important position when it reaches its extinction.
The Hasmonean dynasty[4] (/ËŒhæzməˈniËÉ™n/ (audio); Hebrew: חַשְ××ž×•Ö¹× Ö·Ö¼×Ö´×™×, Ḥašmona’Ä«m) was a ruling dynasty of Judea and surrounding regions during classical antiquity. Between c. 140 and c. 116 BCE the dynasty ruled Judea semi-autonomously from the Seleucids. From 110 BCE, with the Seleucid Empire disintegrating, the dynasty became fully independent, expanded into the neighbouring regions of Samaria, Galilee, Iturea, Perea, and Idumea, and took the title “basileus”. Some modern scholars refer to this period as an independent kingdom of Israel.[5]
The dynasty was established under the leadership of Simon Thassi, two decades after his brother Judas Maccabeus (יהודה המכבי Yehudah HaMakabi) defeated the Seleucid army during the Maccabean Revolt. According to 1 Maccabees, 2 Maccabees, and the first book of The Jewish War by Jewish historian Flavius Josephus (37 CE–c. 100),[6] Antiochus IV moved to assert strict control over the Seleucid satrapy of Coele Syria and Phoenicia[7] after his successful invasion of Ptolemaic Egypt was turned back by the intervention of the Roman Republic.[8][9] He sacked Jerusalem and its Temple, suppressing Jewish and Samaritan religious and cultural observances,[7][10] and imposed Hellenistic practices.[10] The ensuing revolt by the Jews (167 BCE) began a period of Jewish independence potentiated by the steady collapse of the Seleucid Empire under attacks from the rising powers of the Roman Republic and the Parthian Empire.
The author of the First Book of Maccabees regarded the Maccabean revolt as a rising of pious Jews against the Seleucid king who had tried to eradicate their religion and against the Jews who supported him. The author of the Second Book of Maccabees presented the conflict as a struggle between “Judaism” and “Hellenism”, words that he was the first to use.[28] Modern scholarship tends to the second view.
After five years of war and raids, Judah sought an alliance with the Roman Republic to remove the Greeks: “In the year 161 BCE he sent Eupolemus the son of Johanan and Jason the son of Eleazar, ‘to make a league of amity and confederacy with the Romans.’”[45]
The Clan Bruce ruled Scotland from 1306 to 1371. Its last royal member was King David II (1324–1371), upon whose death without issue the throne passed to his nephew Robert Stewart. The Clan continues today through other lines that do not have patrilineal royal ancestry, although the current clan chief, Andrew Bruce, 11th Earl of Elgin, is descended from King Robert Bruce in the female line.
Kingdom at its greatest extent under Salome Alexandra
It is difficult to state at what time the Pharisees, as a party, arose. Josephus first mentions them in connection with Jonathan, the successor of Judas Maccabeus (“Ant.” xiii. 5, § 9). One of the factors that distinguished the Pharisees from other groups prior to the destruction of the Temple was their belief that all Jews had to observe the purity laws (which applied to the Temple service) outside the Temple. The major difference, however, was the continued adherence of the Pharisees to the laws and traditions of the Jewish people in the face of assimilation. As Josephus noted, the Pharisees were considered the most expert and accurate expositors of Jewish law.
During the Hasmonean period, the Sadducees and Pharisees functioned primarily as political parties. Although the Pharisees had opposed the wars of expansion of the Hasmoneans and the forced conversions of the Idumeans, the political rift between them became wider when Pharisees demanded that the Hasmonean king Alexander Jannaeus choose between being king and being High Priest. In response, the king openly sided with the Sadducees by adopting their rites in the Temple. His actions caused a riot in the Temple and led to a brief civil war that ended with a bloody repression of the Pharisees, although at his deathbed the king called for a reconciliation between the two parties. Alexander was succeeded by his widow, Salome Alexandra, whose brother was Shimon ben Shetach, a leading Pharisee. Upon her death her elder son, Hyrcanus, sought Pharisee support, and her younger son, Aristobulus, sought the support of the Sadducees. The conflict between Hyrcanus and Aristobulus culminated in a civil war that ended when the Roman general Pompey captured Jerusalem in 63 BCE and inaugurated the Roman period of Jewish history.
Josephus attests that Salome Alexandra was very favourably inclined toward the Pharisees and that their political influence grew tremendously under her reign, especially in the institution known as the Sanhedrin. Later texts such as the Mishnah and the Talmud record a host of rulings ascribed to the Pharisees concerning sacrifices and other ritual practices in the Temple, torts, criminal law, and governance. The influence of the Pharisees over the lives of the common people remained strong, and their rulings on Jewish law were deemed authoritative by many. Although these texts were written long after these periods, many scholars believe that they are a fairly reliable account of history during the Second Temple era.
The mass and majesty of this world, all<br /> That carries weight and always weighs the same<br /> Lay in the hands of others; they were small<br /> And could not hope for help and no help came:<br /> What their foes like to do was done, their shame<br /> Was all the worst could wish; they lost their pride<br /> And died as men before their bodies died.
She looked over his shoulder<br /> For athletes at their games,<br /> Men and women in a dance<br /> Moving their sweet limbs<br /> Quick, quick, to music,<br /> But there on the shining shield<br /> His hands had set no dancing-floor<br /> But a weed-choked field.
A ragged urchin, aimless and alone,<br /> Loitered about that vacancy; a bird<br /> Flew up to safety from his well-aimed stone:
“I have placed my bow in the clouds, and it will be a sign of the covenant between me and the earth.”
These are the “block transaction” I’ve initially imported (somewhat … haphazardly) into the Rinkeby chain; the total test ETHer cost of this … “dump and semi-permafrost-etching” of the message in testnet was around $121.50 (which might or might not be a good value for printing a book on the Library of Congress’s … wall (for fake, ofc) … I am planning to write a sort of “bounty” to allow others to pay for and sign copying it … piece by piece … to the Ethereum’s “mainnet.” This might be something we …
… [and it was evening and it was morning and now it is the old “tax day”] …
April 15, 2020: I am sort of hacking pushing this stuff onto Rinkeby; it’s “not really liking what I’m doing” which appears to mean … literally the software really isn’t … functioning properly. Here’s files and transactions that were successfully written in “chalk”–meaning they were accepted by the network, and will probably be “mined” and eventually “immutable” (in testnet/Rinkeby). Many of the transactions were refused by the server, it appears to suggest they are “duplicate” (which they are not) and want’s me to “increaes my gasoline bidding offer” in order to … overwrite the previous … (non identical transaction). Maybe I am doing something wrong, maybe not.
From what I’m presenting you can see … the blockchain software really isn’t designed to … "care about what you think or your opinion, or you presenting something like “a version of an implementation plan” for a bill under question–or saving that–what it’s concerned with is “pick a number 1-12” and maybe … some later “condition to revoke” or “alter” … something arbitrary. I think we need to work on “caring about the importance of our written contributions” more, as in beingt able to actually present written contributions … in a system like this wwhich is probably destined to become something like an immutable “legislation record.” There is also a 26K “appears to be a hard limit” on the size of each contract, hence the … numerous hash references for each file.
<span style="font-size:8px;">GUNZIOUUE5H30LY1T!ABYSS.html 861e91a5a582ba5825bf2605990cfaaec58f4966 c7dbbb0cd0face04e4a4c5c8e289177f049dce39 cf1fe352bbee9a920e44d1bd81d08c1e9399504a 8d12f79f9f32e39d18c79c12d7b9fb05a55a10c5 5b94f3f3a47fd83a97b9454b4de27aa9bc0c0ad9 eb743071d2d7ee31b90315011e1881e185f5857f eaa57f9a93de06c57b593d0e9ad3de32241fe1f5 1a519e4195e933a072f9a233594e92441689d3c4<br /> 20f45f7865d7694f1ec155f48393b8d044b4cd70 b26ff67ac6c1908eb35e07eb698f3a910273c2f1<br /> 84338809f407297c43f70d0ce6cf682cd4dde5eb</span>
<span style="font-size:8px;">UNZIOUUE5H30LY1T!ACESHI.html 03bfaea61b7873449c091b855a4d952a11719135 66e2871ef39334962fb75ce34407f825d67ec434 085f9a5ee9b677cd1b7965c2dd093d6bca77f0dc 7012a1f9bed8d89e1e0515b84dd872b629b7b60d db2837a812e97bb4b1e271918de02415e466103f 32040f6ef9dc2378961332835c7869a9ecd50a91 f8d836b29e7525c20e86813c0b601afc3e6da9a1 644125c1ce87a0a9c827e8dacea58a14bb7e11f5 c909934b0689dbbd0d8e06d347e9fb8ad332b4bb 7d44d5a2b060190b3a41c00023173e2568982b12</span>
<span style="font-size:8px;">GUNZIOUUE5H30LY1T!ADIOSAS.html#1: dde69cb2af6599701453fbbb3a0bd7d880d16209 4b47680eb83bfb51ff3e3a7e671c02b7b68ac649 daa61dadd85e4e92f6dc386fd887c487f9fc8191 69df5c40dc70ed272b6ae481c93ba966adee9885 b517d2740e8d5383c73bf790948ed7840187c4fc e291fd040d4690599dca121749ec08450f0f6c79 b91f52a3a681aa2d04dc3af55ce8df460a7ae3c1 5cb047f0151198b83ba52f5cd36d637d2dbda859 9666b0d4d52bc23b249ee7a50bfb3fa2b5a0f848</span>
<span style="font-size:8px;">GUNZIOUUE5H30LY1T!MOROKSRIG.html#1: 03e95b753cba381cb29bb2eafc584690f00caff4 8ad5cfd6dc1be7733be2d7f4cb0cedd00f5f3902 a54ab79af06c89fac1537b0faa0270e35e022570 daf36e641a1b5036d23565f6c9024a64c4b39876</span>
<span style="font-size:8px;">GUNZIOUUE5H30LY1T!MISSISSIPPI.html#1: c6f805a781dc8a12a4ace58910c1b4acc295a32a 5c3a07299e2401fcb7448e6f0356f66408fd043e e9977bebbfd2e716faa8c500e22ed4b79f27cbd3</span>
<span style="font-size:8px;">GUNZIOUUE5H30LY1T!MOLASSES.html#1: e9b2165e3f44ed36faf226645ffbd9ba2be92269 66e2871ef39334962fb75ce34407f825d67ec434 38179f71157e6cd003415ad62c34f5f47d57075a 6638ba4b319b64cd68e7b64c534118dce393bdb8 9d3f2eb7693e0e7d092055e3cc4f16ae90fe323b</span>
<span style="font-size:8px;">GUNZIOUUE5H30LY1T!ALLTA.html#1: f81be6a8830343e9be38c1e41908d676c4309afb<br /> !AMISTAD.html#1: 824cebcb15bf6ba8a9912091654fb4ee033bbbdb | 66e2871ef39334962fb75ce34407f825d67ec434<br /> !ANDERSON.html#1: 33a55bc62f3876b0e34120d564cd9da26cfb24ad<br /> !ATCONGRESS.html#1: 0d97f662ee405e3881927d67803eef5495c87366 !ARTANWORDS.html#1: 2de0c7d3b9a657e475dc987188e2bc6686cb807d !B.html#1: cd4a5a1939c03eb46834cb959b7331dc322b288b !LANDOH.html#1: 6bf55970aa5c8b59e715a19db6f78098bb337c55 MEDICINE.html#7: 514f9c0c12ec08b12e21937311b388038138527a MUAH.html#1: 741ada306a5b3a1e0d4dd7aa3d7c2274936faf53</span><span style="font-size:8px;"> !PIMB.html#1: b56c131d9e67daaae253278b8b08b3eff15d5b1f</span>
The above are examples of “file transactions that appear to have been committed in whole” … there are several partial files written; and I will probably write a “diff system” to only resubmit the missing chunks; in the future… or soon.
GUNZIOUUE5H30LY1T!OUITHEPPL.html#1: 32a4c303e557899e6f7c119bf8e977ffa2369df8 | 66e2871ef39334962fb75ce34407f825d67ec434 … that second hexadecimal number is my “wallet ID” … you can search through Rinkeby’s ledger and see all of the other … TXN’s that were posted today; the plan or hope is that you will abe able to; anyway. The little hack code I used doesa in fact work and produce a contract on the chain, for the first few small tests I did. These needs to be “mined” and that involves some cryptographic … stuff … called “proof of work” that I don’t really understand; but it means there’s a delay, and a bigger delay because there’s “more data.” I do of course have a special afinity for this particular “file” it’s the one where I basically “added” (in my mind) some Bible’s words preceding Revelation 1:1 … to the actual “Bible.” The word in question, of coruse is “dox<s>ic</s>ology.” I think you can send… actual Ethereum there. I’m pretty sure, you could.
dox·ol·o·gy /däkˈsälÉ™jÄ“/
noun<br /> noun: doxology; plural noun: doxologies
- a liturgical formula of praise to God.
They call these identifiers “immutable” … of course this is “testnet1” … I will do “testnet2” which is some name reminiscient of “Robespiere” … probably tomorrow. See reading “immultable” I’m messy, u Tableland; sort of like in unison with the Upanishads. I imagine this is my “birthday present” for this year’s Had’ad day, and I do hope the “immultapl pen” is … enshrined or enschewed or … see etched in the ethereum blockchain … hopefully for good purpose and use “forever.” Imagine that, added to the newly modified GPL2MODS.3 license:
Unless otherwise indicated, this work was written between the Christmas and Easter seasons of 2017 and 2020. The content of this page is released to the public under the GNU GPL v2.0 license; additionally any reproduction or derivation of the work must be attributed to the author, Adam Marshall Dobrin along with a link back to this website, fromthemachine dotty org.
That’s a “.” not “dotty” … it’s to stop SPAMmers. :/
This document is “living” and I don’t just mean in the Jeffersonian sense. It’s more alive in the “Mayflower’s and June Doors …” living Ethereum contract sense and literally just as close to the Depp/C[aster/Paglen (and honorably PK] 'D-hath Transundance__sense of the … new meaning; as it is now published on Rinkeby, in “living contract” form. It is subject to change; without notice anywhere but here–and there–in the original spirit of the GPL 2.0. We are “one step closer to God” … and do see that in that I mean … it is a very real fusion of this document and the “spirit of my life” as well as the Spirit’s of Kerouac’s America and Vonnegut’s Martian Mars and my Venutian Hotel … and my fusion of Guy-A and GAIA; and the Spirit of the Earth … and of course the God given and signed liberties in the Constitution of the United States of America. It is by and through my hand that this document and our X Commandments link to the Bill or Rights, and this story about an Exodus from slavery that literally begins here, in the post-apocalyptic American hartland. Written … this day … April 14, 2020 (hey, is this HADAD DAY?) … in Margate FL, USA. For “official used-to-v TAX day” tomorrow, I’m going to add the “immultible incarnite pen” … if added to the living “doc/app”–see is the DAO, the way–will initi8 the special secret “hidden level” … we’ve all been looking for.
Nor do just mean this website or the totality of my written works; nor do I only mean … this particular derivation of the GPL 2.0+ modifications I continually source … must be “from this website.” I also mean the thing that is built from … bits and piece of blocks of sand-toys; from Ethereum and from Rust and from our hands and eyes working together … from this place, this cornerstone of the message that is … written from brick and mortar words and events and people that have come before this poit of the “sealed W” that is this specific page, and this time. It’s 3:28; just five minutes–or is it four, too layne.
This work is not to be redistributed according to the GPL unless all linked media on Youtube and related sites are intact–and historical references to the actual documented history of the art pieces (as I experience/d them) are also available for linking. Wikipedia references must be available for viewing, as well as the exact version of those pages at the time these pieces were written. All references to the Holy Bible must be “linked” (as they are or via … impromptu in-transit re-linking) to the exact verses and versions of the Bible that I reference. These requirements, as well as the caveat and informational re-introduction to God’s DAO above … should be seen as material modifications to the original GPL2.0 that are retroactively applied to all works distributed under license via this site and all previous e-mails and sites. /s/ wso
Farmacogenómica
Por favor comentar su valoracion
Preguntas ¿Cuál es el diagnóstico más probable? ¿Qué problemas médicos potenciales puede presentar una paciente con esta alteración? ¿Cómo puede esta alteración afectar sus ciclos menstruales?
La madre de una niña de 16 años llama a la clínica por preocupación en cuanto a sus hábitos de alimentación. Señala que no come nada y está obsesionada con el ejercicio y la disminución de peso. También expresa que su hija se ha retirado más de los amigos y la familia. Después de hablar con ella, la paciente entra para exploración física, mide 1.52 m y pesa 38.5 kilogramos. No presenta dificultad aguda alguna, pero parece deprimida. Declara estar preocupada de que sus amigos piensen que esta gorda si come más. Niega cualquier ingestión sobreindulgente de alimentos. Su exploración física es normal, además de piel seca y vello delgado y fino en las extremidades. Las pruebas de laboratorio revelan que presenta anemia, con baja concentración de albúmina y magnesio. Sus pruebas de función hepática y tiroidea resultan normales.
$$n con el radio. {\displaystyle V={\frac {4}{3}}\pi r^{3}.}{\displaystyle V={\frac {4}{3}}\pi r^{3}.}$$
Protestant organizations started mass-producing, mass-marketing, and mass-distributing i mages of J esus, who was always depicted as White. Protestants saw all t he aspirations of t he new American identity in the White Jesus—a racist idea that proved to be i n their cultural s elf-interest. As pictures of t his White J esus s tarted to appear, Blacks and Whites s tarted to make con-nections, c onsciously and unconsciously, between the White God the Father, his White son Jesus, and the power and perfection of White people.
. “ It i s . . . t he con-crete universal, self-determining thought, which constitutes the prin-ciple and character of Europeans,” Hegel once wrote. “ God becomes man, r evealing himself.” I n contrast, African people, he said, were “a nation of children” i n the “first stage” of human development: “ The negro is an example of animal man in all his s avagery and lawlessness.” They could be educated, but t hey would never advance on their own. Hegel’s foundational racist idea justified Europe’s ongoing coloniza-tion of Africa. European colonizers would supposedly bring progress to Africa’s residents, j ust as European enslavers had brought progress to Africans i n the Americas.
I n his Annual Message t o Congress t hree years earlier, J efferson had condemned the “violations of human rights” e nabled by the slave trade and urged Con-gress to abolish it. Congress followed his lead in 1807, after a conten-tious debate over how illegal s lave traders would be punished. Traders, they decided, would be fined under t he Slave Trade Act of 1807. But Congress did nothing to ensure the act’s enforcement.It was an empty and mostly symbolic l aw. The act f ailed to close the door on the ongoing international s lave trade while flinging open the door to a domestic one.
slave trade,
Periodically, t he convention published and cir-culated advice tracts for free Blacks. Abolitionists urged free Blacks to attend church regularly, a cquire English literacy, l earn math, a dopt trades, avoid vice, l egally marry and maintain marriages, evade law-suits, a void expensive delights, a bstain from noisy and disorderly con-duct, a lways act i n a civil and respectable manner, and develop habits of industry, sobriety, and frugality. I f Black people behaved admirably, abolitionists reasoned, t hey would be undermining justifications for slavery and proving that notions of t heir i nferiority were wrong.9This strategy of what can be termed uplift s uasion was based on the idea that White people could be persuaded away from their rac-ist i deas i f t hey saw Black people improving their behavior, uplifting themselves from their l ow station in American society. The burden of r ace relations was placed squarely on the shoulders of Black Ameri-cans. Positive Black behavior, a bolitionist s trategists held, undermined racist i deas, and negative Black behavior confirmed them.
Rhode I sland pastor Samuel Hopkins, an antislavery Puritan, would have found Jefferson’s passage laughable. He had just sent t he con-gress A Dialogue c oncerning t he Slavery of t he Africans. Americans’ s o-called enslavement t o the British was “lighter than a feather” compared to Africans’ e nslavement t o Americans, Hopkins argued.
A Dialogue concerning the Slavery of the Africans available on archive.org
Hopkins became the first major Christian leader outside of t he Society of Friends to forcefully oppose slavery
Mis anotaciones a Infancia en un mundo Digital
un gran ausente en dichos informes es la perspectiva de los bienes comunes y las comunidades de base, que dinamizaría la construcción de hábitats digitales y una triada Estado, Privados y Comunidades, transformándose a otros modelos de gobernanza y sostenibilidad económica más allá de miradas panópticas, acríticas y neoliberales. Conectar esos espacios, más allá de la clase es el gran desafío e implicará pensarnos desde otros roles como ciudadanos y activistas en diálogo y vinculación con comunidades de base, auditando a Estado y privados, en díalogo crítico y constructivo con ellos y con capacidad de agencia más allá de estos.
Activity Streams Fuel.Press/YOURNAME
espectrometría de emisión óptica en un equipo marca Bruker, referencia Q4 Tasman con arco de chispa en atmósfera de argón (Tabla 1). Tabla 1. Composición química de la fundición estudiada (CL) expresada en porcentaje en peso Elemento C Si Mn Cu Cr S Ni P Mo Ceqv CL (%) 3,87 2,72 0,39 0,281 0,2 0,15 0,097 0,074 0,025 4,8
:3 caracterización del material, paos fundamental en la investigacion y desarrollo
W e also n eed to ac kno w le dge h ere the national change s in the form and sc ope of stateactivitie s in m an y W e ste rn e con om ie s. C o ntractin g, d eregulation and privatisation havered uc ed , in both p rac tical and id e ological terms, the capacity for d ire ct state in tervention.T hat is n ot to say that these de vic es do n ot provide n ew forms of state stee rin g and re gu latio n(see be lo w ). T he rule s of en gage m en t de sc ribe the relationship betwee n govern m e nts,em p lo ye rs an d w orkers. T he k ey c hange here , at le ast in th e W est, is fro m a F ord ist, w elfareco rp oratism to a `m ark et m o de l’ wh erein `the pro sp erity o f w orkers will d ep en d o n an abilityto trad e the ir skills, kn ow led ge and en treprene urial ac um e n in an u nfe tte re d global m arketplac e’ (B ro wn & Lau d er, 19 9 6 , p. 3) . A nd the ne w rules o f w ealth c re ation are replacin g thelo gic of F ord ist m ass produc tion w ith ne w `kn ow le dge -based’ system s o f ̄ e xible produ ction.H o we ver, the re are three c ruc ial c ave ats to the last point. F irst, F o rd ist produc tio nsystem s in the W est have no t so m uc h be en replaced as `
check out this.
L o w e r c a s e t h e o r i e s e x p l o r e a s p e c i f i c a r e a o f n e w literacies and/or a new technology, such as the social communicative transactions occurring with text mes-saging (e.g., Lewis & Fabos, 2005 ). Lowercase perspec-tives also include those that explore a focused disciplinary base, such as the semiotics of multimodal-ity in online media (e.g., Kress, 2003 ); a distinctive con-ceptual approach, such as new literacy studies (Street, 1 9 9 5 , 2 0 0 3 ) ; o r o n l i n e l i t e r a c i e s w i t h i n a s p e c i f i c d e v e l -opmental level (e.g., Alvermann, Hutchins, & McDevitt, 2012 ; Marsh, 2011
lowercase theories
soffrire
pretensioni
pretensióne1 (meno com. pretenzióne) s. f. [dal lat. tardo praetensio -onis, der. di praetendĕre «pretendere1»], letter. – 1. Il fatto di pretendere, nelle varie accezioni del verbo, sinon. spesso del più com. pretesa. In partic.: a. L’azione o l’atteggiamento di chi pretende di avere cose a cui non ha pieno diritto o di far cose superiori alle proprie forze: avere, avanzare delle p. su un territorio, su un possesso; che cosa è la nostra pretensione di conoscere il vero? (Leopardi). b. Stima eccessiva di sé, delle proprie capacità o possibilità: una persona piena di pretensione; stupide pretensioni di certi scienziati di cuor meschino (Pirandello). c. Riferito a oggetti, ornamenti, capi di abbigliamento, all’arredamento di ambienti, a locali pubblici, e sim. (di solito in complementi di qualità o di modo), ricercatezza, ostentazione di lusso, di raffinatezza, o più semplicemente ambizione di apparire di qualità o livello superiore: un abito di buona stoffa, ma senza pretensioni; un salotto di troppa p.; un ristorante carissimo e di gran pretensione. d. Richiesta di retribuzione troppo elevata, di ricompense o riconoscimenti eccessivi: sul principio ci fu un po’ d’incaglio per la scarsezza di lavoranti e per lo sviamento e le pretensioni di pochi ch’eran rimasti (Manzoni). 2. In araldica, armi di pretensione, armi di dominî sui quali un sovrano vanta diritti e che inquarta con la propria arme.
frasca
frasca s. f. [etimo incerto]. – 1. a. Ramoscello con foglie: le f. degli alberi; il destrier ch’avea lasciato Tra le più dense f. alla fresca ombra (Ariosto); farsi un letto di frasche; mettere le f. ai piselli, ai fagioli, ecc., ficcarle in terra per appoggio ai legumi che crescono.
albagia
albagìa s. f. [forse der. di alba1, attraverso il sign. di «vento dell’alba»]. – Alterigia, presunzione, boria che deriva da una considerazione troppo alta di sé: trattare, presentarsi con a.; essere pieno d’a.; hanno quattro soldi, e li spendono per vanità, per a. (Goldoni)
ingiuria
ingiùria s. f. [dal lat. iniuria, der. dell’agg. iniurius «ingiusto», comp. di in-2 e ius iuris «diritto»]. – 1. Nel sign. originario, ogni azione contro il diritto, sinon. quindi di ingiustizia, intesa soprattutto come violazione delle norme giuridiche (e pertanto meno grave di iniquità che è violazione dell’equità): D’ogne malizia, ch’odio in cielo acquista, Ingiuria è ’l fine, ed ogne fin cotale O con forza o con frode altrui contrista (Dante), ha per fine la violazione del diritto, che può avvenire per violenza o frode ai danni altrui; per i. propose di rivolere quello che per parole riaver non potea (Boccaccio). 2. a. In diritto civile e penale, offesa recata mediante parole, atti, o mediante l’invio di scritti o disegni, all’onore o al decoro di una persona presente o con la quale si è in comunicazione postale, telefonica o telematica, perseguibile penalmente su querela dell’offeso: i. verbale, reale; i. grave. Nel diritto canonico e nella morale cattolica, in senso lato, violazione del diritto altrui alla fama, violazione considerata come delitto e peccato. b. Nell’uso com., senza preciso riferimento giuridico, offesa al nome, al decoro, all’onore altrui, con parole o atti oltraggiosi: fare i. al nome, all’onore di qualcuno; dire parole, fare un gesto d’ingiuria. In senso più concr., detto ingiurioso, frase fortemente offensiva: gli rivolse le i. più volgari; lo coprì d’ingiurie; si scambiarono atroci i.; dalle ingiurie passarono a vie di fatto. c. Per estens., atto o discorso o pensiero che implicitamente comporti un giudizio sfavorevole, tale da urtare la suscettibilità altrui: mi fanno i. supponendo che io abbia agito così per interesse, mi fanno torto, cioè, a pensarlo. 3. letter. Offesa, danno recato alle cose e alle persone da fatti naturali, dal corso del tempo, dalla sorte; per lo più al plur.: le i. delle stagioni; le i. del destino; mostrava nei lineamenti del volto le i. del tempo.
sproposito
spropòṡito s. m. [der. di proporzionato, col pref. s- (nel sign. 1), quasi a dire «che è fuor di proposito, fuori di ciò che qualcuno si è proposto di dire o di fare»]. – 1. a. Atto avventato e inconsulto, tale da comportare gravi conseguenze, cui si è indotti dall’ira, dalla disperazione e sim.; soprattutto nelle espressioni fare, commettere uno s.; non so davvero che sproposito faccio, stamattina! (Pirandello). b. Atto, discorso, frase e sim. fatti o detti in modo del tutto inopportuno: è stato uno s. vendere la casa; smettila di provocarmi, se no mi fai dire degli spropositi! c. Errore, sbaglio, per lo più grave: uno s. di lingua, di grammatica; un discorso pieno di spropositi; uno s. madornale; hai detto un sacco di spropositi; egli giocando non facea che spropositi, de’ quali rimproverato ... rispose ch’era con la testa quattro leghe lontano (Casanova). 2. fam. Quantità eccessiva, esagerata, spec. con riferimento a consumi, valori in denaro, costi e spese: in questa casa si consuma uno s. di olio; ha mangiato uno s. di cioccolata, e ora sta male; con valore avverbiale, uno s., molto, esageratamente: il quadro è bello, ma l’ho pagato uno s.; la nuova automobile consuma uno sproposito. 3. A sproposito, locuz. avv., fuor di proposito, inopportunamente, in modo non attinente (contrario di a proposito, v. proposito): fare una cosa a s.; parlare, rispondere, interloquire a s.; parlava molto e sempre a s., una gaffe dopo l’altra (Palazzeschi).
cascamorti
cascamòrto s. m. [dalla locuz. cascare morto]. – Innamorato, spasimante: le è sempre intorno quel c.!; fare il c., mostrarsi innamorato quasi al punto di venir meno per amore, con atti languidi e svenevoli: fa il c. con tutte le ragazze che incontra. D’uso poco comune il femm. cascamorta.
albagia
albagìa s. f. [forse der. di alba1, attraverso il sign. di «vento dell’alba»]. – Alterigia, presunzione, boria che deriva da una considerazione troppo alta di sé: trattare, presentarsi con a.; essere pieno d’a.; hanno quattro soldi, e li spendono per vanità, per a. (Goldoni). http://www.treccani.it/vocabolario/albagia/
Un 7-Eleven de la ciudad de Brisbane deberá pagar casi 200.000 dólares de multa por aprovecharse de sus trabajadores extranjeros y crear registros falsos para encubrir estas acciones ilegales. Este caso se suma a la serie de escándalos de explotación que afectan a esta franquicia, seis de ellas en la capital de Queensland. Updated Updated 05/06/2018 By R.O. Share Share on Facebook Share on Twitter Un Tribunal del Circuito Federal multó a Avinash Pratap Singh, gerente y dueño parcial de una gasolinera 7-Eleven en East Brisbane, con 32.130 dólares y a la empresa que dirige S & A Enterprises con otros160.650 dólares tras una investigación realizada en 2015 por la Defensoría de Empleo Justo (Fair Work Ombudsman).Los inspectores de la Defensoría hallaron que los empleados, todos ellos jóvenes estudiantes provenientes de la India, recibieron 5,593 dólares menos en total por los períodos en que trabajaron en la gasolinera en 2014.Singh y su empresa admitieron que pagaron a sus empleados 14,14 por hora, que está por debajo del salario mínimo legal, y que además no les dieron a estos jóvenes el dinero que les correspondía por horas extras trabajadas ni por las jornadas durante los fines de semana y los días festivos.A otro empleado de la gasolinera se le pagó un 25 por ciento menos de lo que le correspondía (4,439 dólares) por los cinco meses que trabajó, mientras que a otro joven se le dio 1,154 dólares menos durante las siete semanas que estuvo empleado en ese lugar (41 por ciento menos(.Singh y S & A Enterprises también proporcionaron datos falsos a la oficina central de 7-Eleven sobre los salarios, según un comunicado de la Defensoría de Empleo Justo.El juez Angelo Vasta indicó que la entrada de datos falsos sobre las horas y los salarios dados a los empleados de esa gasolinera en el sistema de pagos “crearon registros en los que parece que los empleados recibieron las tasas de salarios fijados por los laudos actuales, incluyendo las tasas de recargo y las pagas por horas extraordinarias de trabajo, las cuales no tienen relación con las horas de trabajo o las tasas reales por hora (que se les pagó)”.El juez además obligó a los responsables a pagar a la Defensoría 2,247 por los costes legales.
El análisis metalográfico reveló una microestructura de martensita revenida y austenita retenida con baja dureza, que puede ser el resultado de dos causas fundamentales. La primera de ellas, consiste en la aplicación de un tratamiento térmico inadecuado, en el que se aporta energía térmica en exceso por una temperatura de revenido muy alta o un tiempo de revenido demasiado largo. La otra razón fundamental consiste en que, la aleación del acero no contiene una cantidad de carbono suficiente para que la martensita formada obtenga una alta dureza.
los aceros sin intersticio son aceros con Nb y Ti, reaccionan con C y S, prácticamente sin carbono. Estos aceros son de fácil conformación y, por lo tanto son de potencial utilización en la industria automotriz.
Los hierros fundidos son aleaciones de hierro y carbono con una cantidad de este último elemento superior al que tienen los aceros al carbono. Los elementos que siempre se encuentran presentes en los hierros fundidos son: C, Mn, Si, P y S, aunque en algunos tipos se pueden encontrar: Ni, Cr, Cu, etc. Al igual que los aceros, los hierros fundidos son aleaciones de hierro y carbono, pero se diferencian de éstos en los siguientes aspectos: - mayor contenido de carbono. - en su estructura puede aparecer la ledeburita, perlita, ferrita y grafito. - mayor contenido de Si, Mn, P y S. - menor punto de fusión 1 150 °C, lo que provoca una mayor fluidez. - poca capacidad a la deformación.
Los hierros fundidos son aleaciones de hierro-carbono-silicio, que por lo general contienen 2.4% y 0.5-3% de Si, pasan por una reacción eutéctica durante su solidificación.
inter-Arab cleavages through its emphasis on the ‘Northern Tier.’”
<br>
Source Excerpt: Letter to Frank Maria, August 18, 1958, on Middle East, in reference to Senator's Flanders' resolution S. Con Res. 106 (to which JFK is opposed because he says "it proceeds from some false premises"). "First, at the heart of his reasoning is the belief that the primary source of unrest in the Middle East is the existence of the State of Israel and the support which the United States has given to that Middle East democracy. I would not deny that Israel has sharpened feelings and antagonisms within the Middle East and that it provides one more rallying point for Arab nationalism. However, it seems to me a gross misreading of Arab nationalism to believe that it became anti-Western only as a result of U.S. support for Israel--without recognizing the historic roots of Arab nationalism, the balkanization of the Middle East which occurred after the breakup of the Ottoman empire at the conclusion of World War I, and the role which Russia has played in the Middle East, most notably in the last five years. [para break] Secondly, I would suggest that, in so far as American policy is responsible, there are other mistakes which we have made--to believe, for example, that Nasserism is a mere outgrowth of Russian Communism, and the delusion of the Baghdad Pact which represents a belief that military alliances can provide stability and which has encouraged inter-Arab cleavages through its emphasis on the 'Northern Tier.' It was never realistic to believe that we could set off Iraq against Cairo. They were simply not two equivalent weights on the scale. Indeed, one of my reservations about the Flanders resolution is precisely the implication that there is a solution. There are corrections, improvements and gambles that we can take in the Middle East; confusion rests in believing that the type of pulsations which are vibrating through that area can be controlled by any single line of policy, however well motivated."
Data Source: https://doi.org/10.5064/F68G8HMM/UQY9L4
Full Citation: JFK to Frank Maria, August 18, 1958, Pre-presidential Papers-Senate Files, Box 693, JFK Library.
MICROORGANISMO FÁRMACO (DOSIS, DURACIÓN) COMENTARIOS Estreptococos Estreptococos susceptibles a penicilina,b S. gallolyticus (MIC 0.12 μg/mLb) • Penicilina G (2-3 mU IV c/4 h por 4 semanas) Puede usarse ampicilina o amoxicilina (2 g IV c/4 h) si no está disponible la penicilina. • Ceftriaxona (2 g/d IV en dosis única por 4 semanas) Puede usarse ceftriaxona en pacientes con alergia no inmediata a penicilina. • Vancomicina (15 mg/kg IV c/12 h por 4 semanas) Usar vancomicina en pacientes con alergia grave o inmediata a β lactámicos. • Penicilina G (2-3 mU IV c/4 h) o ceftriaxona (2 g IV c/d) por 2 semanas Más Gentamicinad (3 mg/kg c/d IV o IM en dosis únicae o dividida en dosis iguales c/8 h por 2 semanas) Evitar el tratamiento de 2 semanas cuando el riesgo de toxicidad por aminoglucósidos es alto y en endocarditis de
Microorganismo
Unificar la S con la del catalogo
By controlling the localization of frac-ture at the nanoscopic and microscopic scale, S. purpuratus con-trols the macroscopic morphology of the tooth tip, resulting in the maintenance of a robust and sharp tip.
Kind of like sharpening a knife but more intricate.
s importante conformar un grupo de trabajo que funcione de acuerdo con las reglas de operación de los grupos institucionales del CCH.
También hay que identificar quién y cómo almacenarán los datos recabados.
s. Incluso con es-ta metáfora de interacción, los usuarios podrían construir complejasaplicaciones web hechas sobre IPython, usando subárboles internospara las partes internas de las aplicaciones y las partes externas paraaquello con lo que el usuario web puede interactuar, de una mane-ra similar a ocultar las partes internas de la escritura al lector de mitesis (pero, por ahora, esto va más allá de lo que este escrito quiereproponer)
Una idea similar de combinar documentos interactivos y aplicaciones web es propuesta por la gente de Eve.
Prior to analysis, weremoved unrealistically short response times (<200 m) that likelyrepresented natural braking responses to slow the vehicle asopposed to a reaction to the lead vehicle. Only 5 samples (0.3% ofthe data) were removed as a result. The analysis revealed thatbraking response times were longer for the interesting condition(M¼0.94 s), compared to boring (M¼0.92 s) and baseline con-ditions (M¼0.90 s; F(2,60)¼3.19, p<0.05,G2¼0.02).The turn signal task response time was measured from the onsetof the lead vehicle's turn signal (left or right) until the driver'sresponse was made. Accuracy was the percentage of correct re-sponses on this task. Response times for the turn signal task did notvary across the different conditions (Baseline, M¼1.06 s; Boring:M¼1.07 s; Interesting, M¼1.07 s; F(2,60)¼0.76, p¼0.48,G2¼0.002), nor did signal accuracy, which tended to be high(M¼99% in all conditions; F(2,60)¼0.24, p¼0.79,G2¼0.003)
inferential statistics that was used here was the p-value
Este artículo me recordó a la pastelería estadounidense “Carlo´s Bakery”, La cual fue fundada en el año 1910 y ha pasado de generación en generación desde entonces y hasta a fecha. Esta pastelería se ha dado a conocer mundialmente gracias al Reallity Show “Cake Boss” en el que se muestra la manera de operar de la empresa a la hora de cumplir con los pedidos de pasteles. En esta empresa se puede identificar el modelo CAVA, es una empresa familiar, tienen la responsabilidad de transmitir el patrimonio a los integrantes de la familia, todos los miembros de la familia están involucrados en el negocio de diferentes maneras, ya sea en el área administrativa, área de ventas o de producción. También se puede ver reflejado el modelo de las 4 C pues le han dado Continuidad a negocio cuidado siempre el buen funcionamiento de la empresa a través de los integrantes, cuidan a la Comunidad que trabaja con ellos, pues se preocupan por su bienestar y se aseguran que duren mucho tiempo trabajando con ellos, incluso trabajadores sin parentesco con los dueños tienen años trabajando con ellos igual que sus familiares, crean también Conexiones entre sus vecinos asegurándose de trasmitir valores tanto a clientes, trabajadores y personas que los rodean, finalmente tienen buena estrategia de Comando, pues se han adaptado a las exigencias del mercado actual y se han hecho de herramientas para mantenerse vigentes, sobre todo a través de los medios de comunicación.
On 2016 Feb 16, Lydia Maniatis commented:
Another example of the problem discussed by Teller can be found in Pelli (1990), who is proposing a model of perception:
"In order to make the model as general as possible, yet still be able to measure its parameters, we need threeassumptions,or constraints. First we assume that the observer's level of performance increases monotonically with the contrast of the signal (when everything else is fixed). This guarantees that there will be a unique threshold. Secondly, as indicated on the diagram by the prefix contrast-invariant we assume that the calculation performed is independent of the contrast of the effective stimulus, which is its immedi- ate input. Together, assumptions 1 and 2 are a linking hypothesis. They imply that the observer's squared contrast threshold (which we can measure) is pro- portional to the effective noise level (which is inaccessible). Thirdly, we assume that the equivalent input noise is independent of the amplitude of the input noise and signal, or at least that it too is contrast- invariant, independent of the contrast of the effective image. These assumptions allow us to use two threshold measurements at different external noise levels to estimate the equivalent noise level. In effect, the assumptions state that the proportionality con- stant and the equivalent noise Neq are indeed constant, independent of the contrast of the effective image. These three assumptions are just enough to allow us to make psychophysical measurements that uniquely determine the parameters of our black-box model. Our model makes several testable predictions, as will be discussed below."
It's worth noting that the main function of the rationale seems to be one of practical convenience.
Theoretically, Pelli (1990) is proposing to make the case that: "the idea of equivalent input noise and a simplify- ing assumption called 'contrast invariance' allow the observer's overall quantum efficiency (as defined by Barlow, 1962a) to be factored into two components: transduction efficiency (called 'quantum efficiency of the eye' by Rose, 1948) and calculation efficiency..."
Although he claims his model makes testable predictions, he also states that they had not, as of publication been tested.
Pelli and Farrell (1999) seem to be referencing the untested, two-component model when they state that: "it is not widely appreciated that visual sensitivity is a product of two factors. By measuring an additional threshold, on a background of visual noise, one can partition visual sensitivity into two compo- nents representing the observer鳠efficiency and equivalent noise. Although they require an extra threshold measurement, these factors turn out to be invariant with respect to many visual parameters and are thus more easily characterized and understood than their product, the traditional contrast threshold."
No references are provided to suggest the proposal has been corroborated. This problem is not remedied by the subsequent statement that: "Previous authors have presented compelling theoreti- cal reasons for isolating these two quantities in order to understand particular aspects of visual function (refs. 3 㠱3)," since all of the references predate the Pelli (1990) claims. Conveniently, the authors "ignore theory, to focus on the empirical properties of the two factors, especially their remarkable invari- ances, which make them more useful than sensitivity"). Ignoring theory unfortunately seems to be a hallmark of modern vision science.
In this way, Pelli papers over a theoretical vacuum via technical elaboration of an untested model.
Both Pelli (1990) and Pelli and Farrell (1999) are referenced by more recent papers as a support for the use of the "Equivalent noise" model.
Pelli (1990) is cited by Solomon, May & Tyler (2016), without a further rationale for adopting the model (I've commented on that article here: https://pubpeer.com/publications/62E7CB814BC0299FBD4726BE07EA69).
Dakin, Bex, Cass and Watt (2009) cite Pelli and Farrell (1999), their rationale being that the model "has been widely used elsewhere."
I feel inclined to describe that what is going on here (it is not uncommon) as a kind of "theory-laundering," where ideas are proposed uncritically, then uncritically repeated, then become popular, and their popularity acts as a substitute for the missing rationale. Is this science?
On 2017 Jul 25, Donald Forsdyke commented:
LECTIN PATHWAY STUDIES WITH PLANT MANNOSE-BINDING LECTINS
Papers on the lectin pathway (LP) of complement activation in animal sera generally refer to animal mannose-binding lectins (MBLs), with little reference to work with plant MBLs. For example, citing May and Frank (1973), this fine paper states: "Reports of unconventional complement activation in the absence of C4 and/or C2 predate the discovery of LP." Actually, a case can be made that the discovery of the LP predates May-Frank.
The MASP-binding motif on animal MBL, which is necessary for complement activation, includes the amino acid sequence GKXG (at positions 54-57), where X is often valine. The plant lectin concanavalin-A (Con-A) has this motif at approximately the same position in its sequence (the 237 amino acid subunit of Con-A had the sequence GKVG at positions 45-48). The probability of this being a chance event is very low. Indeed, prior to the discovery of MASP involvement, Milthorp & Forsdyke (1970) reported the dosage-dependent activation of complement by Con-A.
As far as I am aware, it has not been formally shown that MASP is involved in the activation of the complement pathway by this plant MBL. Our studies in the 1970s demonstrated that Con-A activates complement through a cluster-based mechanism, which is consistent with molecular studies of animal MBL showing “juxtaposition- and concentration dependent activation” (Degn et al. 2014). References to our several papers on the topic may be found in a review of innate immunity (Forsdyke 2016).
Degn SE et al. (2014) Complement activation by ligand-driven juxtaposition of discrete pattern recognition complexes. Proc Natl Acad Sci USA 111:13445-13450. Degn SE, 2014
Forsdyke DR (2016) Almroth Wright, opsonins, innate immunity and the lectin pathway of complement activation: a historical perspective. Microb Infect 18: 450-459. Forsdyke DR, 2016
May JE, Frank MM (1973) Hemolysis of sheep erythrocytes in guinea pig serum deficient in the fourth component of complement. I. antibody and serum requirements. J Immunol 111: 1671-1677. May JE, 1973
Milthorp PM, Forsdyke DR (1970) Inhibition of lymphocyte activation at high ratios of concanavalin A to serum depends on complement. Nature 227:1351-1352 Milthorp P, 1970
Yaseem et al. (2017) Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2. FASEBJ 31:2210-2219 Yaseen S, 2017
On 2017 Mar 25, Gerhard Holt commented:
by Gerhard Holt
Research into cellular aging and the Senescence-Associated Secretory Phenotype indicates that selective elimination of senescent cells may provide substantial benefits - potentially including increases in healthspan.[1]
Many surface antigens may be differentially expressed on senescent/SASP cells relative to non-senescent cells. Ideally, the chosen cell surface antigen(s) would be highly specific to senescent/SASP cells to reduce collateral damage to non-senescent cells. For example, EFNB1 and/or EFNB3 may be appealing targets.[1]
These "Senescence Specific Surface Antigen" targets might - if necessary - include potentially spurious surface antigens that may have negligible causal relation to SASP but are nevertheless fairly specific. One could presumably also target multiple "SSSA"s to achieve better coverage.
Several methods to target cells expressing these SSSA's might be used - including :
(1) CAR-T cells vs the antigen(s). [2]
Pros :
Extensive removal of target cells. Long lasting surveillance against subsequent reemergence of the senescent/SASP cells with those surface antigens.
Cons :
May cause collateral damage or impair other important functions (for example - potentially - wound healing).
Questions :
Could one potentially embed a switchable "suicide gene" in the CAR-T cells, or perhaps a reversible switch to transiently deactivate the CAR-Ts either systemically or locally?
Could one also embed a highly specific artificial set of inducible surface antigens on the CAR-Ts to facilitate subsequent removal or modification by mAbs or minicells (see below)?[3]
(In the longer term one might also potentially examine logic-gated CAR-T cell approaches for increased specificity, or to target the absence of a surface antigen that is differentially expressed on Non-senescent cells ? [3])
(2) mAbs vs the antigen(s).
Pro :
Well established approach.
Con :
No longer term surveillance.
(3) Minicells vs the antigen(s). [4]
Pros :
Highly specific targeting. Minicells could also be targeted to multiple different SSSA's.
Can specifically carry cytotoxic medications to the target cells.
Can add siRNAs to the minicells to perform more subtle intracellular actions (perhaps inducing apoptosis, reversing (or accelerating) aberrant intracellular processes, attracting CAR-T cells, or modifying natural immune responses to the cell, or expressing alternative surface antigens).
Could be used in addition to CAR-T approaches, or perhaps as a backup to help selectively deactivate CAR-T cells if responses cause excessive collateral damage or if one needs to (perhaps temporarily) damp the response.
Con :
No long term surveillance.
Targeting senescence specific surface antigens may be a useful way to selectively destroy senescent/SASP cells.
The application of CAR-T cell, mAb, and minicell approaches might be effective in this task, and will hopefully be the subject of further research.
[1] Zhu, Y. Tchkonia, T. et al. (2015) The Achilles' heel of senescent cells: from transcriptome to senolytic drugs. Aging Cell. 2015 Aug;14(4):644-58. doi: 10.1111/acel.12344. Epub 2015 Apr 22.
www.ncbi.nlm.nih.gov/pubmed/25754370
[2] Kochenderfer JN et al. (2010) Adoptive transfer of syngeneic T cells transduced with a chimeric antigen receptor that recognizes murine CD19 can eradicate lymphoma and normal B cells. Blood. 2010 Nov 11;116(19):3875-86. doi: 10.1182/blood-2010-01-265041. Epub 2010 Jul 14.
www.bloodjournal.org/content/bloodjournal/116/19/3875.full.pdf
[3] Roybal, K.T., et al. (2016). Precision tumor recognition by T cells with combinatorial antigen-sensing circuits. Cell 164, 770–779. dx.doi.org/10.1016/j.cell.2016.01.011
www.sciencedirect.com/science/article/pii/S0092867416000519
[4] MacDiarmid, J.A. et al. (2009) Sequential treatment of drug-resistant tumors with targeted minicells containing siRNA or a cytotoxic drug. Nat. Biotechnol. 27, 643–651.
www.nature.com/nbt/journal/v27/n7/pdf/nbt.1547.pdf
On 2017 Mar 23, University of Kansas School of Nursing Journal Club commented:
Team Members: Jason Tracy, Abigail Spare, Julia Damman, Laura Thompson, Sophie Bono, Maeve Markey. [Class of 2017]
Background
In our class, we took time to study shared governance in acute care organizations and looked at the importance of shared governance in regards to all nursing positions. This article not only touches on the importance of shared governance, but also explores the processes needed to help direct patient care nurses transition their knowledge, skills, and attitudes into the leadership role that would facilitate shared governance. Our team was especially interested in the idea of shared governance, and liked how this particular article discussed an intervention to increase shared governance by empowering nurses with leadership. This is an interesting, practical intervention that could be implemented with nurses.
Methods
This was a descriptive qualitative study that took place at a university medical center hospital with 300 adult beds in southeastern U.S. Through partnership, the CNO and CON faculty developed a Frontline Innovations (FI) group that help mentor frontline nurses with leadership skills, problem solving strategies, and evidence based to fix identified operational failures. The group included 12 frontline nurses from 4 different medical surgical units chosen by the CNO based on their leadership potential. Frontline nurses are extremely important to include in change process because they have direct impact to patients outcomes.
Interviews were conducted to reveal the steps of process improvement, and analysis of interviews determine recurring themes which were divided into process and outcome measures describing staff, administration, and faculty interaction. Engagement was identified as a component of the process theme and was observed through both verbal and nonverbal communication with the CNO, as well as focused role playing activities with interprofessional groups. The nurses that engaged in these group activities were then responsible for sharing what they learned with their peers on the unit (Dearmon et al. 2015).
The study ultimately affected nursing administration and executives as well because of their influence in the structures and processes of various units. This influence carried over to the care delivery of frontline nurses give. Shared governance distributes power, resources, and information as equally as possible, so it is important that both administration and frontline nurses work together (Dearmon et al. 2015).
Findings
Outcome measures included collaboration, empowerment, confidence, and lifelong learning. Collaboration was found to be important for the creation of the organization’s new shared governance model. It allowed members to work together to achieve a common goal, strengthen group morale, and improve the credibility of decisions making process. Nurses began to feel empowered when they felt their voices were heard by the CNO and changes were made. Nurses who were given the opportunity to visit other facilities that has shared governance model returned to their own organization feeling empowered to brought back shared governance model in their unit. In order to instill confidence that the new shared governance model would work for the organization, Frontline Innovations group members coached nurses through the new project and allowed them to use the process to see success for themselves (Dearmon et al. 2015).
Creating the Frontline Innovations group proved to be an effective way to influence change at the bedside through the implementation of a shared governance model. All disciplines involved learned to trust each other and this transferred to practice, improving collaboration in patient care. Nurses became more enthusiastic about the care they provided because they felt their voices were being heard and thus began to realize they had the ability to change practice when gaps were seen. The transition from a culture of administrative decision-making to one of staff engagement and shared decision-making forged an organization with all members willing to take responsibility for workplace obstacles (Dearmon et al. 2015).
Nursing Implications
The healthcare industry continues to become more complex as new discoveries are made. As these complexities expand the nursing practice becomes more specialized, making it more difficult for the executives in charge to understand the needs of the individual environments. Only by including the nurses that work in direct patient care areas can executives get a full picture of the operations and needs of the units. The literature shows that although both executive and front line nurses desire to collaborate, there is a gap to be filled before this can occur. The literature shows that there are means by which this gap can be bridged by developing mentorship programs, from which front line nurses can gain the knowledge needed to participate in counsels that effect change within the organization. This also helps nurses find their voice and the desire to work independently with their executive mentors to make quality improvements within their units. The end result was better working relationships between the two groups and more productive initiatives in providing better patient care (Dearmon et al. 2015). This means the healthcare industry is able to provide more efficient services and better patient outcomes due to changes made by the people involved in doing the work. As new nurses getting ready to enter the healthcare system, it is reassuring to know that our point of view is just as important as that of a nurse executive. Stepping into a new organization, we bring a fresh set of eyes that can see things to which others have become accustomed to. Being able to affect change within an organization is an important factor when choosing a career, and this article helps support this initiative. The section that discussed nurses being able to work independently gave rise to the idea of working and improving within specific system. Individually both systems can do a certain amount of work, but without collaboration they can ultimately fail. However, this also requires leadership to be in place in both systems. This means that although the executive officers may be the faces of the organization, nurse leaders in each system are called to step up to the task of effecting change.
If the literature is found to be valid and reliable, then many changes are sure to come. There is already a push for hospitals to obtain Magnet status. The evidence found in this article supports the Magnet program and the need for more nurses stepping into leadership roles. This may also change how nurses are integrated into an organization by mandating new employees to be trained in the organization's leadership development program. The end product would include more staff educated in how to effectively work within their unit’s structure and how their unit collaborates best with other units. This alone can provide a multitude of solutions to decrease expenses and the amount of waste, provide more efficient care, and increase employee morale.
Reference
Dearmon, V., Riley, H., Mestas, G., & Buckner, B. (2015). Bridge to shared governance: Developing leadership of frontline nurses. Nursing Administration Quarterly, 39(1), 69-77. doi: 10.1097/NAQ.0000000000000082
s in the inheritance of this con-flict—in which the philosophical epistêmê is pitched against the sophis-tic tekhne, whereby all technical knowledge is devalued—that the essence of technical entities in general is conceived:
Interesting that we are dealing here with another split, a split that impacted an entire history of philosophy, similar to the letter spirit split or the writing speech split.
hombres muy capaces y competentes para su trabajo.
Enseñanza: Ser capaz y competente para nuestro trabajo es un don de Dios. Arrepentimiento: Señor, ayudame a cumplir en todo con mis cliente,s para que sepan que yo te adoro y que tu estás conmigo, y pueda ser un testimonio de tu realidad en mi vida y que yo vivo sometido a tí. Aplicación: No posponer más mis la terminación de mis desarrollos.
porque podría perdidas de protección al ser insoluble en agua y soluble en grasas. Al añadirle el terpeno se busca que la estructura del jabón se adhiera al filtro. Una vez realizadas las pruebas in-vitro y determinar la eficiencia del proceso se podrá realizar el diseño de una planta piloto con las condiciones adecuadas a la formulación más estable del jabón. 6AntecedentesSe llaman jabones las sales de sodio o de potasio de los ácidos grasos. Por extensión el ácido puede ser cualquier carboxilato ("tall-oil", "rosin-oil"), y el metal alcalino puede reemplazarse por una amina, amida o etanol amina. Si se usa un metal pesado polivalente se obtiene una substancia liposoluble. El jabón se prepara mediante saponificación de los triglicéridos de origen vegetal o animal por unasolución de hidróxido alcalino. De manera general se puede decir que los carboxilatos de cadena corta (C10-12) son rápidamente soluble en agua, producen espuma y toleran el agua dura. Sin embargo son también irritantes para las pieles sensibles. Por otra parte los carboxilatos en C18 saturados o insaturados no son irritantes y pueden usarse en jabones y cremas fáciles, pero se solubilizan en agua muy lentamenteLos Jabones humectantes poseen elementos que permiten que la piel mantenga su nivel de humedad adecuado.Las leches solares y cremas son emulsiones (toda emulsión es la mezcla de grasa o aceite, agua y tenso activo, donde el tenso activo hace que se junte la parte acuosa con la oleosa). Las emulsiones son buenos vehículos para contener los filtros porque forman una capa sobre la piel de espesor adecuado lo que ayuda a hacer efectivo dicho filtro y a mantener la hidratación de la piel. Los jabones son agentes tensioactivos o surfactantes. Se trata de sustancias que disminuyen la tensión superficial de un líquido o que actúan sobre la superficie de contacto entre dos fases, por ejemplo dos líquidos inmiscibles. Estos se pueden clasificar en:Aniónicos: contienen carga negativa en solución acuosa (jabones, alquilbenceno sulfonatos lineales, alfa olefín sulfonatos, dialquil sulfonatos, entre otros). Catiónicos: contienen carga positiva en solución acuosa (aminas grasas y sales, sales de amonio cuaternarias, entre otros). No iónicos: no se disocian en el agua, carecen de carga (alquil fenoles polietoxilados, alcoholes grasos polietoxilados, entre otros). Anfóteros: dependiendo del pH se comportan como aniónicos o catiónicos (aminoácidos, las betaínas o los fosfolípidos).(Rojas, 2015; Jean, 2002)Se denomina protectores solares o foto protectoresa todos aquellos, que se aplican sobre lapiel con el fin de protegerla de los efectos perjudiciales de las radiaciones solares ultravioleta A (UVA) y/o ultravioleta B (UVB). Esto es posible porque en su composición llevan unas sustancias denominadas filtros, capaces de frenar la acción de uno y/u otro tipo de radiación. Los filtros solares se pueden clasificar en físicos (Actúan por reflexión de la luz) y químicos (Actúan por absorción de la radiación solar ultravioleta). Los filtros químicos u orgánicos son los másusados. Sonsustancias químicas de síntesis que actúan como cromóforos absorbiendo energía. Al incidir un fotón sobre el filtro químico, éste absorbe la energía, y al volver a su estado inicial libera este exceso de energía en forma de radiación fluorescente o transformándose enun isómero o fotoproducto relativamente activoA diferencia de las pantallas físicas, cada filtro químico tiene un espectro deabsorción determinado.Los filtros que absorben UVBmás utilizados son derivados del ácido p-amino-benzoico (PABA), octocrileno homosalato, 4-metilbenciliden alcanfor, etil-hexil-metoxicinamato, fenil-bencimidazol sulfónico.Mientrasque los filtros físicos más utilizados son: el óxido de zinc, el dióxido de titanio y la mica. (Cázares, 2013;Castanedo,2013)La flavonoides son un conjunto de antioxidantes que se encuentran en algunas frutas y vegetales de hoja verde como espinaca, acelgas, lechuga, etc. Estos tipos de antioxidantes se caracterizan por contener en su interior vitamina E, la cual es insoluble en agua.(Popa, 2014)Investigando los trabajos realizados, se encontró que existen productos en el mercado que incluyen el protector solar, pero esos jabones son elaborados de forma casera, y los industrializados tienen un nivel de FPS 15-50, lo cual no brinda la protección que buscamos, se quiere desarrollar un producto con una mayor protección, y que garantice la salud de la piel. Con productos estandarizados. Por otro lado la avobenzona es un compuesto que proviene de los dibenzoilmetano, este tipo de compuesto activoes solo soluble en grasas y acetites.(SUNJIN, 2013)JustificaciónLa investigación consiste en crear un jabón facial que contenga en su fórmula un filtro solar, para ayudar a evitar las quemaduras de la piel provocadas por el sol. Este jabón es del tipo humectante, complementado por la adición de un filtro solar. Para evitar que se desperdicie el producto, y debido a las características aplicación directa se enfocó el proyecto en el área facial. Además de que es la parte más expuesta al sol. La mayor problemática que se podría mencionar seria la solubilidad de nuestro filtro solar en agua, pero para evitar ese tipo de problemas ya contemplados, utilizamos compuestos de filtros solares insolubles en agua.Se busca ampliar el conocimiento de las propiedades físicas y químicas de los jabones con protector solar, con resultados estadísticos experimentales generados con las variables del proceso. Se espera diseñar un proceso que sea rentable. La mejora con respecto de los trabajos anteriores es la búsqueda de una formulación que no se retire de la piel al lavar el jabón.El resultado de la investigación será un diseño de una planta piloto, y la formulación con mejores propiedades fisicoquímicas y reológicas. Metodología propuestaSe realizará el jabón por el método de saponificación,añadiendo un filtro solar.Las variablesdel proceso experimental son: tenso activos, concentración de filtro solar, y tiempo de exposición a los rayos solares. El resultadoestadístico se empleara para elaborar el diseño y presupuesto de la planta piloto, basado en la formulación más estable. Se buscará un proceso con mayor eficiencia, y que no genere impacto ambiental.Se aplicara metodología univariante para el estudio de la formulación, realizando triplicado de las pruebas delAnalito.La investigación conrespectoa la planta piloto solo abarca el diseño, dejando el conocimiento para posterior aplicación.Para obtener una muestra representativa se realizara muestreo en diferentes zonas del jabón, para una posterior homogenización y dilución, las pruebas se realizaran por triplicado. Las pruebas realizadas a la muestra de jabón son las siguientes:1.Estudio de propiedades reológicas2.Análisis espectrofotométrico3.Determinación de pH. 4.Prueba de saponificación5.Pruebas de formulación 6.Pruebas de vida útil7.Fuente de luz8.Pruebas de compuesto activoFactibilidadSe cuenta con la asesoría de expertos en métodos espectrofotométricos para el análisis de los filtros solares y en biotecnología, y es factible conseguir las instalaciones y materiales necesarios, en el CUCEI,o en la Escuela Politécnica de Guadalajara. Los insumos no representan costos elevados. El laboratorio de Reológia del CUCEI cuenta con reómetro rotacional, y el laboratorio de instrumentación cuenta con espectrofotómetro y potenciómetro. Se cuenta con software estadístico.Referencias[1]Castanedo, J., Torres, B. & Valdés, G. (2013). Evaluación in vitro de la protección uva de los bloqueadores solares para prescripción en México. Mayo 16, 2017, de Gaceta Médica de México Sitio web: http://www.anmm.org.mx/GMM/2013/n3/GMM_149_2013_3_292-298.pdf[2]Cázares, J., Álvarez, B., González, G., & Pérez, A. (2013). Evaluación in vitro de la protección uva de los bloqueadores solares para prescripción en México. Gaceta Médica de México, 149(3), 292-298.[3]Rojas, E. (2015). Cambios significativos de la NOM-073-SSA1-2015, Estabilidad de fármacos y medicamentos, así como de remedios herbolarios.Mayo 16, 2017, de Secretaria de Salud Sitio web: http://www.amegi.com.mx/curso_practico/Estabilidades.pdf[4]Jean, L. (2002). Surfactantes, Cuaderno FIRP 300 A Versión # 2Laboratorio FIRP Escuela de Ingeniería Química, universidad de los andes Mérida 5101 Venezuela[5]Mitrinova, Z., Tcholakova, S., Popova, Z., Denkov, N., Dasgupta, B. R., & Ananthapadmanabhan, K. P. (2013). Efficientcontrol of the rheological and surface properties of surfactant solutions containing C8–C18 fatty acids as cosurfactants. Langmuir, 29(26), 8255-8265.[6]Popa, E. (2014). Método para la obtención de flavonoides de hojas de Tamarindus indica Lin.Mayo 16, 2017de MULTIMEDSitio web: http://www.multimedgrm.sld.cu/articulos/2010/v14-3/2.html [7]SUNJIN. (2013). Catálogos de Cosmética. Mayo 14, 2017, de SUNJIN Sitio web: http://www.sunjinbs.com/data/catalog/2013.03%20Part1%20Catalog%20Final%20-%20SPANISH.pdf[8]UANL. (2005). Desarrollan jabones con protección solar y repelente para mosquitos. Abril1, 2017 de Universidad Autónoma de Nuevo LeónSitio web: http://www.uanlmexico.mx/noticias/investigacion/desarrollan-jabones-con-proteccion-solar-y-repelente-para-mosquitos.htmlMostrar barra lateralPágina 1 de 4AlejarAcercarRetroceder páginaAvanzar páginaPantalla completaImprimir
no entiendo lo que quieres decir con podría perdidas
SOLLUX CAPTOR
yall know the drill by now
Sollux rather transparently divides into "sol-lux", the Latin words for "sun" and "light", respectively. As such, his name would literally mean 'Sunlight Catcher'.
If one would switch the S and P in his name it becomes "Pollux Castor." Pollux and Castor are the two brightest stars in the constellation of Gemini. It is also worth noting that Pollux is a red giant, while Castor is bluish white, complementing the red/blue duality theme. Castor and Pollux were famous mythological twins, which is where Gemini - Latin for "twins" - gets its name. Pollux and Castor were also the names of two characters in the movie Face/Off, a Nicolas Cage flick that came out the same year as Con Air and one that John Egbert has a poster of in his room.
Aceite de orégano (origanum vulgare):efecto antifúgnico sofre a. flavus.FACTIBILIDADEl equipo debe ser económicamente viable, así como tener un diseño muy parecido a uno industrial, que este no altere la composición química de la muestra, con la capacidad adecuada para distintos tipos de muestras (diseño optimo), asegurando así que el rendimiento de este sea el mejor posible ajustando los distintos factores que afectaran la eficiencia de obtención de producto.REFERENCIASMatiz, G., Osorio, M. R., Camacho, F., Atencia, M., & Herazo, J. (2012). Diseño y evaluación in vivo de fórmulas para acné basadas en aceites esenciales de naranja (Citrus sinensis), albahaca (Ocimum basilicum L) y ácido acético.Biomédica,32(1), 125-133.ARANGO B, O. S. C. A. R., Bolaños, F., Villota, O., HURTADO B, A. N. D. R. É. S., & Toro, I. (2012). Optimización del rendimiento y contenido de timol de aceite esencial de orégano silvestre obtenido por arrastre con vapor.Biotecnología en el sector agropecuario y agroindustrial,10(2), 217-226.García-Camarillo, E. A., Quezada-Viay, M. Y., Moreno-Lara, J., Sánchez-Hernández, G., Moreno-Martínez, E., & Pérez-Reyes, M. C. J. (2006). Actividad antifúngica de aceites esenciales de canela (Cinnamomum zeylanicum Blume) y orégano (Origanum vulgare L.) y su efecto sobre la producción de aflatoxinas en nuez pecanera [Carya illinoensis (FA Wangenh) K. Koch].Revista Mexicana de Fitopatología,24(1).Ribeiro, O. V., Alva, A., & Valles, J. M. (2001). Extracción y caracterización del aceite esencial de jengibre (Zingiber officinale).Alimentaria,1(1), 38-42.
APA no alfabético.
Bueno
Los resultados indican un buen comportamiento electroquímico de las películas delgadas de almidón, con conductividades aproximadas de 3x10-3 S cm-1 y una buena actividad rédox que permite la acumulación de carga en el dispositivo armado.
mediante una película conductora a base de almidón de yuca, se pudo acumular energía
proceso de estabilizaci´on de sustratos en sistemas anaerobios, con buenos resultados en la remoci´on de la Materia Org´anica (medidos en t´erminos de mg DBO5 / l o de mg DQO / l), reducci´on del contenido de s´olidos, ajustes de pH entre otros; mejorando as´ ı la calidad de los vertimientos y reduciendo los impactos.
Para el trato de lixiviados
Las muestras de tejido adiposo se obtuvieron durante el acto quirúrgico de tres mujeres con antecedentes de salud que fueron sometidas a abdominoplastias asociadas a hernias umbilicales en el servicio de cirugía del Hospital General Docente "Enrique Cabrera". Para ello se tomaron entre 30 y 50 g de grasa de la zona de la herida quirúrgica. Este estudio fue aprobado por el Comité de Ética de la Investigación s del Instituto de Hematología e Inmunología (IHI), La Habana, Cuba y todos los donantes firmaron un consentimiento informado escrito.
De hecho, el lugar de procedencia de las muestras puede ser cualquiera. Pero verdaderamente se preferiría buscar oportunidad de aprovechamiento de restos, no necesariamente "desperdicios" de origen animal.
Se compraron plátanos de tamaño medio sin lesiones o hematomas en la piel del bazar para garantizar que el proceso experimental fuera justo. Estos plátanos tenían un índice de color de 4 (verde-amarillo) de acuerdo con la guía de maduración del banano CSIRO (CSIRO, 1972). Se realizó una gran variedad de experimentos piloto para establecer los efectos de colocar las cáscaras de plátano en una solución al 0,5% de Na 2 S 2 O 5 , utilizando diferentes concentraciones de HCl y NaOH, usando diferentes cantidades de pasta de plátano, en la calidad del plástico producido. En base a los resultados de los 12 experimentos piloto, se seleccionaron los siguientes 2 experimentos y se repitieron cuatro veces: Se sumergen las cáscaras de plátano en una solución al 0,5% de Na 2 S 2 O 5 antes de los procesos de ebullición y puré y se utilizan soluciones de HCl 0,1 M y NaOH en la producción del plástico. Sumergir las cáscaras de plátano en una solución al 0,5% de Na 2 S 2 O 5 antes de los procesos de ebullición y puré y usar soluciones de 0.5 M de HCl y NaOH en la producción del plástico. Estos tratamientos se seleccionaron en función de la calidad del plástico producido por medio del grosor, la resistencia y la vida útil. Preparación de pieles de banano: Las cáscaras de los plátanos se eliminaron con un cuchillo de acero inoxidable. Un vaso de precipitados de 800 ml se llenó con agua destilada y se colocó sobre un quemador Bunsen. Las cáscaras de plátano se colocaron en el vaso de precipitados y se cocieron durante 30 minutos. Después del proceso de ebullición, el vaso se retiró del mechero Bunsen y las cáscaras se decantaron fuera del agua y se colocaron sobre y se cubrieron con una gasa seca, se dejaron secar durante 30 minutos. Después de que las cáscaras se secaron, se colocaron en un vaso de precipitados limpio de 800 ml. Usando un mezclador de mano, las cáscaras se hicieron puré hasta que se formó una pasta fluida. Producción del plástico: Se colocaron 25 ml de pasta de plátano en cada vaso de 50 ml. Se añadieron 3 ml de HCl y la mezcla se mezcló usando una varilla de agitación de vidrio. Se añadieron 2 ml de propan-1, 2, 3-triol a cada vaso de precipitados. La mezcla se agitó de nuevo. Se añadieron 3 ml de NaOH y la mezcla se agitó una vez más. La mezcla se vertió en una placa Petri y se colocó en el horno a 130 ° C. Fue horneado durante media hora. Materiales y precauciones de seguridad: Todas las mediciones se hicieron de la forma más precisa posible. Por precauciones de seguridad, se usaron guantes quirúrgicos durante todo el experimento. El experimento se llevó a cabo en un labaratory en Koc High School y se utilizó el siguiente equipo: Pipeta de vidrio Vasos Mechero Bunsen Varilla agitadora de vidrio Horno placa de Petri Gasa Escala de primavera PRUEBA DE FUERZA: La resistencia del plástico se determinó aplicando una fuerza de tracción 4N sobre el plástico desde los lados opuestos y determinando si el plástico se rompió o no. El grosor del plástico se determinó usando una regla. La vida útil (descomposición) se evaluó mediante una inspección visual a diario (el oscurecimiento del plástico sugirió la descomposición). Se registraron todos los datos cualitativos y cuantitativos
lo que han hecho otros. proceso
La plata es un metal muy electropositivo (+0.799 V), y es desplazada de la solución por prácticamente todos los metales (Bard y Faulkner, 2001), depositándose con gran velocidad en forma de polvo negro sin ninguna adherencia, de acuerdo con la siguiente reacción:(1)Ag+(ac) + e− = Ag° (s)E° = +0.799 VLa única manera de evitar este inconveniente es desplazando el potencial hacia valores más electronegativos; por ejemplo, mediante la disminución de la concentración de los iones de Ag+ en la solución. En la práctica esto se realiza utilizando sales complejas, como son los cianuros dobles, amoniacos dobles, etc.; en ese caso se producen las reacciones:
Muy interesante!! este es uno de las reacciones por la cual la plata llega a ponerse negra.
El proceso de relación intercultural en general puede dividirse en cinco etapas:
• Encuentro: Aceptación de la interacción.(aceptación dentro de cada grupo ). • Respeto: Trato con dignidad, Trato como sujetos. (tratar con respeto e igualdad). • Diálogo horizontal: Interacciones con igualdad de oportunidades. • Comprensión mutua: Entendimiento del(os) otro(s). Enriquecimiento mutuo, sintonía y resonancia (Capacidad y disposición para comprender e incorporar lo planteado por el otro (a). Empatía. • Sinergia: Obtención de resultados que son difíciles de obtener desde una sola perspectiva y de forma independiente.
Todos los proyectos, sin apoyo de los BC, se pagan dentro de los tres primeros años de su puesta en mar- cha (TRI). Se observa que el benefcio por BC (tabla 8), aunque se trate de una cantidad considerable en com- paración con la inversión inicial (entre 16% y 19%), no es signifcativo en relación con el VPN acumulado a lo largo de la vida útil del proyecto (tabla 9); esto se re±e - ja en que los proyectos se siguen pagando dentro del tercer año. Para este caso, la potencia instalada total sería de 96.9 MW, representando 0.18% de la capacidad total instalada para la generación de energía a nivel nacio- nal. Signifcando 0.23% para C²E y 0.75% para los PIE´s. En cuanto a la generación de energía, se obtendría una producción máxima anual de 848.84 GWh, represen- tando 0.34% del total nacional, 0.51% respecto a C²E y 0.99% para los PIE´s. Para el consumo total de Jalisco (12.000 GWh año -1 aprox.), la energía producida repre- sentaría 7.10% aproximadamente. Se mitigarían 0.388 t de CO 2 e por habitante, representando 9.96% de la pro- ducción de t de CO 2 per-cápita nacional (3.9 t año -1 ). Con un consumo anual de energía eléctrica por habi- tante de 108.21 kWh, que representa 5.26% del consumo per-cápita nacional (2.057 kWh año -1 ) y un 7.10% para el consumo per-cápita estatal (1.524 kWh año -1 ),
es muy teórico diría casi imposible porque son dimensiones grandes (todo jalisco), pero esto ayuda para poner aterrizar este proyecto a comunidades no tan grandes
On 2017 Mar 23, University of Kansas School of Nursing Journal Club commented:
Team Members: Jason Tracy, Abigail Spare, Julia Damman, Laura Thompson, Sophie Bono, Maeve Markey. [Class of 2017]
Background
In our class, we took time to study shared governance in acute care organizations and looked at the importance of shared governance in regards to all nursing positions. This article not only touches on the importance of shared governance, but also explores the processes needed to help direct patient care nurses transition their knowledge, skills, and attitudes into the leadership role that would facilitate shared governance. Our team was especially interested in the idea of shared governance, and liked how this particular article discussed an intervention to increase shared governance by empowering nurses with leadership. This is an interesting, practical intervention that could be implemented with nurses.
Methods
This was a descriptive qualitative study that took place at a university medical center hospital with 300 adult beds in southeastern U.S. Through partnership, the CNO and CON faculty developed a Frontline Innovations (FI) group that help mentor frontline nurses with leadership skills, problem solving strategies, and evidence based to fix identified operational failures. The group included 12 frontline nurses from 4 different medical surgical units chosen by the CNO based on their leadership potential. Frontline nurses are extremely important to include in change process because they have direct impact to patients outcomes.
Interviews were conducted to reveal the steps of process improvement, and analysis of interviews determine recurring themes which were divided into process and outcome measures describing staff, administration, and faculty interaction. Engagement was identified as a component of the process theme and was observed through both verbal and nonverbal communication with the CNO, as well as focused role playing activities with interprofessional groups. The nurses that engaged in these group activities were then responsible for sharing what they learned with their peers on the unit (Dearmon et al. 2015).
The study ultimately affected nursing administration and executives as well because of their influence in the structures and processes of various units. This influence carried over to the care delivery of frontline nurses give. Shared governance distributes power, resources, and information as equally as possible, so it is important that both administration and frontline nurses work together (Dearmon et al. 2015).
Findings
Outcome measures included collaboration, empowerment, confidence, and lifelong learning. Collaboration was found to be important for the creation of the organization’s new shared governance model. It allowed members to work together to achieve a common goal, strengthen group morale, and improve the credibility of decisions making process. Nurses began to feel empowered when they felt their voices were heard by the CNO and changes were made. Nurses who were given the opportunity to visit other facilities that has shared governance model returned to their own organization feeling empowered to brought back shared governance model in their unit. In order to instill confidence that the new shared governance model would work for the organization, Frontline Innovations group members coached nurses through the new project and allowed them to use the process to see success for themselves (Dearmon et al. 2015).
Creating the Frontline Innovations group proved to be an effective way to influence change at the bedside through the implementation of a shared governance model. All disciplines involved learned to trust each other and this transferred to practice, improving collaboration in patient care. Nurses became more enthusiastic about the care they provided because they felt their voices were being heard and thus began to realize they had the ability to change practice when gaps were seen. The transition from a culture of administrative decision-making to one of staff engagement and shared decision-making forged an organization with all members willing to take responsibility for workplace obstacles (Dearmon et al. 2015).
Nursing Implications
The healthcare industry continues to become more complex as new discoveries are made. As these complexities expand the nursing practice becomes more specialized, making it more difficult for the executives in charge to understand the needs of the individual environments. Only by including the nurses that work in direct patient care areas can executives get a full picture of the operations and needs of the units. The literature shows that although both executive and front line nurses desire to collaborate, there is a gap to be filled before this can occur. The literature shows that there are means by which this gap can be bridged by developing mentorship programs, from which front line nurses can gain the knowledge needed to participate in counsels that effect change within the organization. This also helps nurses find their voice and the desire to work independently with their executive mentors to make quality improvements within their units. The end result was better working relationships between the two groups and more productive initiatives in providing better patient care (Dearmon et al. 2015). This means the healthcare industry is able to provide more efficient services and better patient outcomes due to changes made by the people involved in doing the work. As new nurses getting ready to enter the healthcare system, it is reassuring to know that our point of view is just as important as that of a nurse executive. Stepping into a new organization, we bring a fresh set of eyes that can see things to which others have become accustomed to. Being able to affect change within an organization is an important factor when choosing a career, and this article helps support this initiative. The section that discussed nurses being able to work independently gave rise to the idea of working and improving within specific system. Individually both systems can do a certain amount of work, but without collaboration they can ultimately fail. However, this also requires leadership to be in place in both systems. This means that although the executive officers may be the faces of the organization, nurse leaders in each system are called to step up to the task of effecting change.
If the literature is found to be valid and reliable, then many changes are sure to come. There is already a push for hospitals to obtain Magnet status. The evidence found in this article supports the Magnet program and the need for more nurses stepping into leadership roles. This may also change how nurses are integrated into an organization by mandating new employees to be trained in the organization's leadership development program. The end product would include more staff educated in how to effectively work within their unit’s structure and how their unit collaborates best with other units. This alone can provide a multitude of solutions to decrease expenses and the amount of waste, provide more efficient care, and increase employee morale.
Reference
Dearmon, V., Riley, H., Mestas, G., & Buckner, B. (2015). Bridge to shared governance: Developing leadership of frontline nurses. Nursing Administration Quarterly, 39(1), 69-77. doi: 10.1097/NAQ.0000000000000082
On 2017 Mar 25, Gerhard Holt commented:
by Gerhard Holt
Research into cellular aging and the Senescence-Associated Secretory Phenotype indicates that selective elimination of senescent cells may provide substantial benefits - potentially including increases in healthspan.[1]
Many surface antigens may be differentially expressed on senescent/SASP cells relative to non-senescent cells. Ideally, the chosen cell surface antigen(s) would be highly specific to senescent/SASP cells to reduce collateral damage to non-senescent cells. For example, EFNB1 and/or EFNB3 may be appealing targets.[1]
These "Senescence Specific Surface Antigen" targets might - if necessary - include potentially spurious surface antigens that may have negligible causal relation to SASP but are nevertheless fairly specific. One could presumably also target multiple "SSSA"s to achieve better coverage.
Several methods to target cells expressing these SSSA's might be used - including :
(1) CAR-T cells vs the antigen(s). [2]
Pros :
Extensive removal of target cells. Long lasting surveillance against subsequent reemergence of the senescent/SASP cells with those surface antigens.
Cons :
May cause collateral damage or impair other important functions (for example - potentially - wound healing).
Questions :
Could one potentially embed a switchable "suicide gene" in the CAR-T cells, or perhaps a reversible switch to transiently deactivate the CAR-Ts either systemically or locally?
Could one also embed a highly specific artificial set of inducible surface antigens on the CAR-Ts to facilitate subsequent removal or modification by mAbs or minicells (see below)?[3]
(In the longer term one might also potentially examine logic-gated CAR-T cell approaches for increased specificity, or to target the absence of a surface antigen that is differentially expressed on Non-senescent cells ? [3])
(2) mAbs vs the antigen(s).
Pro :
Well established approach.
Con :
No longer term surveillance.
(3) Minicells vs the antigen(s). [4]
Pros :
Highly specific targeting. Minicells could also be targeted to multiple different SSSA's.
Can specifically carry cytotoxic medications to the target cells.
Can add siRNAs to the minicells to perform more subtle intracellular actions (perhaps inducing apoptosis, reversing (or accelerating) aberrant intracellular processes, attracting CAR-T cells, or modifying natural immune responses to the cell, or expressing alternative surface antigens).
Could be used in addition to CAR-T approaches, or perhaps as a backup to help selectively deactivate CAR-T cells if responses cause excessive collateral damage or if one needs to (perhaps temporarily) damp the response.
Con :
No long term surveillance.
Targeting senescence specific surface antigens may be a useful way to selectively destroy senescent/SASP cells.
The application of CAR-T cell, mAb, and minicell approaches might be effective in this task, and will hopefully be the subject of further research.
[1] Zhu, Y. Tchkonia, T. et al. (2015) The Achilles' heel of senescent cells: from transcriptome to senolytic drugs. Aging Cell. 2015 Aug;14(4):644-58. doi: 10.1111/acel.12344. Epub 2015 Apr 22.
www.ncbi.nlm.nih.gov/pubmed/25754370
[2] Kochenderfer JN et al. (2010) Adoptive transfer of syngeneic T cells transduced with a chimeric antigen receptor that recognizes murine CD19 can eradicate lymphoma and normal B cells. Blood. 2010 Nov 11;116(19):3875-86. doi: 10.1182/blood-2010-01-265041. Epub 2010 Jul 14.
www.bloodjournal.org/content/bloodjournal/116/19/3875.full.pdf
[3] Roybal, K.T., et al. (2016). Precision tumor recognition by T cells with combinatorial antigen-sensing circuits. Cell 164, 770–779. dx.doi.org/10.1016/j.cell.2016.01.011
www.sciencedirect.com/science/article/pii/S0092867416000519
[4] MacDiarmid, J.A. et al. (2009) Sequential treatment of drug-resistant tumors with targeted minicells containing siRNA or a cytotoxic drug. Nat. Biotechnol. 27, 643–651.
www.nature.com/nbt/journal/v27/n7/pdf/nbt.1547.pdf
On 2017 Jul 25, Donald Forsdyke commented:
LECTIN PATHWAY STUDIES WITH PLANT MANNOSE-BINDING LECTINS
Papers on the lectin pathway (LP) of complement activation in animal sera generally refer to animal mannose-binding lectins (MBLs), with little reference to work with plant MBLs. For example, citing May and Frank (1973), this fine paper states: "Reports of unconventional complement activation in the absence of C4 and/or C2 predate the discovery of LP." Actually, a case can be made that the discovery of the LP predates May-Frank.
The MASP-binding motif on animal MBL, which is necessary for complement activation, includes the amino acid sequence GKXG (at positions 54-57), where X is often valine. The plant lectin concanavalin-A (Con-A) has this motif at approximately the same position in its sequence (the 237 amino acid subunit of Con-A had the sequence GKVG at positions 45-48). The probability of this being a chance event is very low. Indeed, prior to the discovery of MASP involvement, Milthorp & Forsdyke (1970) reported the dosage-dependent activation of complement by Con-A.
As far as I am aware, it has not been formally shown that MASP is involved in the activation of the complement pathway by this plant MBL. Our studies in the 1970s demonstrated that Con-A activates complement through a cluster-based mechanism, which is consistent with molecular studies of animal MBL showing “juxtaposition- and concentration dependent activation” (Degn et al. 2014). References to our several papers on the topic may be found in a review of innate immunity (Forsdyke 2016).
Degn SE et al. (2014) Complement activation by ligand-driven juxtaposition of discrete pattern recognition complexes. Proc Natl Acad Sci USA 111:13445-13450. Degn SE, 2014
Forsdyke DR (2016) Almroth Wright, opsonins, innate immunity and the lectin pathway of complement activation: a historical perspective. Microb Infect 18: 450-459. Forsdyke DR, 2016
May JE, Frank MM (1973) Hemolysis of sheep erythrocytes in guinea pig serum deficient in the fourth component of complement. I. antibody and serum requirements. J Immunol 111: 1671-1677. May JE, 1973
Milthorp PM, Forsdyke DR (1970) Inhibition of lymphocyte activation at high ratios of concanavalin A to serum depends on complement. Nature 227:1351-1352 Milthorp P, 1970
Yaseem et al. (2017) Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2. FASEBJ 31:2210-2219 Yaseen S, 2017
On 2016 Feb 16, Lydia Maniatis commented:
Another example of the problem discussed by Teller can be found in Pelli (1990), who is proposing a model of perception:
"In order to make the model as general as possible, yet still be able to measure its parameters, we need threeassumptions,or constraints. First we assume that the observer's level of performance increases monotonically with the contrast of the signal (when everything else is fixed). This guarantees that there will be a unique threshold. Secondly, as indicated on the diagram by the prefix contrast-invariant we assume that the calculation performed is independent of the contrast of the effective stimulus, which is its immedi- ate input. Together, assumptions 1 and 2 are a linking hypothesis. They imply that the observer's squared contrast threshold (which we can measure) is pro- portional to the effective noise level (which is inaccessible). Thirdly, we assume that the equivalent input noise is independent of the amplitude of the input noise and signal, or at least that it too is contrast- invariant, independent of the contrast of the effective image. These assumptions allow us to use two threshold measurements at different external noise levels to estimate the equivalent noise level. In effect, the assumptions state that the proportionality con- stant and the equivalent noise Neq are indeed constant, independent of the contrast of the effective image. These three assumptions are just enough to allow us to make psychophysical measurements that uniquely determine the parameters of our black-box model. Our model makes several testable predictions, as will be discussed below."
It's worth noting that the main function of the rationale seems to be one of practical convenience.
Theoretically, Pelli (1990) is proposing to make the case that: "the idea of equivalent input noise and a simplify- ing assumption called 'contrast invariance' allow the observer's overall quantum efficiency (as defined by Barlow, 1962a) to be factored into two components: transduction efficiency (called 'quantum efficiency of the eye' by Rose, 1948) and calculation efficiency..."
Although he claims his model makes testable predictions, he also states that they had not, as of publication been tested.
Pelli and Farrell (1999) seem to be referencing the untested, two-component model when they state that: "it is not widely appreciated that visual sensitivity is a product of two factors. By measuring an additional threshold, on a background of visual noise, one can partition visual sensitivity into two compo- nents representing the observer鳠efficiency and equivalent noise. Although they require an extra threshold measurement, these factors turn out to be invariant with respect to many visual parameters and are thus more easily characterized and understood than their product, the traditional contrast threshold."
No references are provided to suggest the proposal has been corroborated. This problem is not remedied by the subsequent statement that: "Previous authors have presented compelling theoreti- cal reasons for isolating these two quantities in order to understand particular aspects of visual function (refs. 3 㠱3)," since all of the references predate the Pelli (1990) claims. Conveniently, the authors "ignore theory, to focus on the empirical properties of the two factors, especially their remarkable invari- ances, which make them more useful than sensitivity"). Ignoring theory unfortunately seems to be a hallmark of modern vision science.
In this way, Pelli papers over a theoretical vacuum via technical elaboration of an untested model.
Both Pelli (1990) and Pelli and Farrell (1999) are referenced by more recent papers as a support for the use of the "Equivalent noise" model.
Pelli (1990) is cited by Solomon, May & Tyler (2016), without a further rationale for adopting the model (I've commented on that article here: https://pubpeer.com/publications/62E7CB814BC0299FBD4726BE07EA69).
Dakin, Bex, Cass and Watt (2009) cite Pelli and Farrell (1999), their rationale being that the model "has been widely used elsewhere."
I feel inclined to describe that what is going on here (it is not uncommon) as a kind of "theory-laundering," where ideas are proposed uncritically, then uncritically repeated, then become popular, and their popularity acts as a substitute for the missing rationale. Is this science?
Para introducir la torca, una experiencia común es el abrir una puerta y para hacerlo, esmás sencillo empujar en el lado de la puerta más alejado de las bisagras porque empujar ellado más cercano a las bisagras requiere considerablemente más fuerza, aunque se requierehacer el mismo trabajo para abrir una puerta. Por otro lado, la experiencia de la aceleraciónangular posiblemente se ha observado en una patinadora sobre hielo, en la cual aumenta laaceleración al momento de cerrar los brazos y disminuye cuando extiende los brazos.Introduciremos a la torca como una medida de la fuerza total que hace que un objetorote alrededor de un eje. En una analogía, en la cinemática lineal, la fuerza neta es lo quehace que un objeto acelere, mientras que la torca neta es la acción que provoca que unobjeto adquiera aceleración angular. Así como la fuerza es una cantidad vectorial, tambiénlo es la torca, de hecho es el producto vectorial (cruz) entre el radio vector en donde seaplica la fuerza y la fuerza aplicada. La dirección de la torca depende de la dirección enque se aplica la fuerza
APLICACIONES Geociencias: La podemos relacionar con la inercia rotacional del planeta TIC´s: como aumentar o disminuir la torca de un motor mediante engranajes. Materiales: Como podemos aumentar o disminuir la longitud de la palanca para aplicar mas fuerza de acuerdo a los materiales que se usen.
Para seguir analizando la interacción entre diferentes objetos, por ejemplo, el movi-miento de las bolas en el billar o la energía cinética liberada al momento del choque de unmeteoro con la Tierra, es necesario introducir los conceptos de colisiones y conservaciónde energía. Estos principios son válidos incluso en los grandes colisionadores de hadrones,en los cuales se alcanzan rapideces cercanas al de la luz
APLICACIONES Geociencias: como dos bloques geológicos pueden colisionar y dependiendo de su densidad estos se van a comportar, caso de la subducción de placas o de los limites de colisión tal es el caso de la placa continental de la india chocando con la placa euroasiática. TIC´s: Desarrollar una aplicación que permita detectar el choque entre dos partículas y sus acciones tras la colisión y ofrecer una representación gráfica de como se crean las componentes de la colisión en una gráfica de 2D Materiales: Aplicar distintos materiales para estudiar como se produce un choque mayor o como se amortigua una colisión de mejor forma y esto se puede aplicar a la industria de los automóviles.
A lo largo de la historia de la física, se han mantenido invariables ciertos principios,como es el caso de la conservación de la energía; la energía no se crea ni se destruye, sólose transforma. En esta práctica analizaremos la conversión de energía cinética a potencialy viceversa
Aplicaciones: Geociencias: desde como gira un planeta alrededor de su eje y como disminuye de acuerdo a como pasa el tiempo hasta TIC´s: diseñar un mecanismo en el cual se guarde la energía que se pierde al frenar en los automóviles y esta energía guardarla por un tiempo determinado y mediante programas enviarla a la llantas que dan el impulso de acuerdo a como el auto requiera impulsarse. Materiales: con que materiales sustentables se pude resguardar energía (calorífica) o innovar un material que pueda recubrir a objetos y que se disminuya el coeficiente de fricción para que la energía se disperse lo menos posible.
RESPONSIVE: 1- Se muestra un cuadro blanco con filtros que no se tiene que mostrar. 2- Demasiado espacio entre las fotos, mirar la creatividad. 3- Los cta´s de "favorito" y "enviar a casting" tienen que ser un poco más grandes. 4- Las "x" de los filtros sobra 5- No hay manera de aplicar los filtros, falta un cta par aplicar los filtros.
7- El banner inferior es diferente, no es tan gordo. 8- La Red Carpet (mismos comentarios que en la Búsqueda normal)
RESPONSIVE: 1- Encima de más filtros de Búsqueda se está mostrando una caja blanca de fitlros que no se tiene que mostrar. 2- Cuando pincho sobre el cta "Más filtros de Busqueda" se muestran los filtros con una "x" en cada uno de ellos. No tienen que estar esas "x". También echo en falta un cta para aplicar los filtros que seleccione. No hay forma de aplicar los filtros. 3- Hay demasiado espacio entre las fotos. Ver la Creatividad.
5- Los cta´s "Favoritos" y "enviar a casting" tienen que ser más grandes. 7- El banner inferior es muy grande. Mirar creatividad. 8- Cuando seleccionas varios perfiles y se llena la caja gris de "selecciones" con los perfiles selccionados tiene que mostrarse un "Ver mas". Po otro lado la caja gris es muy ancha. Tiene que ser como en las creatividad. 9- En el RedCarpet cuando se accede a él tiene que ocupar toda la pantalla. Como en la creatividad. 10- En el Red Carpet las 3 opciones de menú (compartir publicación, etc) No se tienen que mostrar así. Mirar creatividad.
INMA CUESTA CHAT SELECCIONAR
Los cta´s de "Chat" y "Seleccionar" no tienen nada que ver con la creatidad original. Tienen que tener la misma altura.
Yet even in is Jass was perhaps the fi d y what he actu· II d' ore by what he and others h k irst to eel W a y id , s ac led to an uninspiring . b are hitneld a d' h accomplish as a poet. Doug· a,nd con~umed hjs time whii: r -tha_t of harberin ~sh eartening example of geniu~
I feel as if getting recognized by Douglass was a great achievement.
Whitfield's ach~arer of black America's a et~pl e earned him lasting recog-c I h ievement w· f' n is avery h' ie t e could have attained than b as o ten measured m poets. Yet even in is Jass was perhaps the fi d y what he actu· II d' ore by what he and others h k irst to eel W a y id , s ac led to an uninspiring . b are hitneld a d' h accomplish as a poet. Doug· a,nd con~umed hjs time whii: r -
Why was it so important to get Douglas's stamp of approval? Is he the one that tell people if they have talent?
Now I sh ould like to show that learn in g is possible in the case o f these logical-mathematical structures, but on one con dition—that is, th at the st r u ct u r e wh ich you w an t t o t each t o the su bject s can be supported by simpler, more elementary, logical- math ematical structures.
This is similar to the process for teaching complex mathematical topics; CRA- Concrete, representational, abstract.
It is only when they themselves are in firm possession of this logical st r u ct u r e, w h en t hey h ave con st r uct ed it for t h emselves accor d in g t o the developmen t al law s which we shall discuss, that they succeed in understanding correctly the lin guistic expression .
Isn't this the true meaning of learning? To understand a concept so well that they can logically explain it to themselves or another? That is when true mastery is accomplished.
inventor del point and click
El point and click se usa en informática desde los años 70. También se ha usado en juegos mucho antes de Maniac Mansion (1987), incluso con interfaces por lista de verbos).
Aunque fueron los propios Ron Gilbert y Gary Winnick los que se autoproclamaron inventores del género point and click en su campaña en Kickstarter. No existe tal género. Todas las aventuras gráficas, utilicen interfaces gráficas tipo point and click o de cualquier otro, pertenecen al mismo género. Un género no se define por un tipo de interfaz o un tipo de control.
n "a robation for a month to stay m his ber 26, asking h1111 to ~ve .H~ h: ar!le that he will not give any infom1a-own House: And he will [give . pfi d ·h L1· mits of Space as will be H ·u be con m to sue · . tion to the enemy. e wt . "1'> Washington's reply was not surpns-thought proper by your Excellency. h • t c.or her husband "to come • . ld . es but er reques L< ing He wished he cou say y , . 1· h1·s 1·ntent to return • · p k fi tl · rty days 1111p 1es out and remain at Graeme ar or 11 , f the E11emy." further-. · · tl e Q
Elizabeth approaches General Washington in the same way Drinker does, yet she gets denied by him unlike the Quaker wives of the Virginia Exile Crisis. What made Washington say yes to the Quaker wives yet deny Fergusson? I believe that that this excerpt from the book shows that Fergusson approached General Washington in a different way than the Quaker wives and it led to her failure. She tried to appeal to his sympathy for her husband by lowering his sentence. The Quaker women used the rhetoric of sympathy not for their husbands but for themselves. They begged him that they would suffer without their husbands, thus bringing the attention and sympathy to themselves and away from the husbands.
He claimed that students entered physics with a remarkably coherent and articulate the-ory (suggested in Figure 5.2 ) that competed directly with Newtonian physics in instruction. McCloskeys theory theory included a strong parallel in con-tent to medieval scientists ideas, such as those of John Buridan and Galileo. In contrast to others, however, he did not say much about process-of-change similarities and, for example, did not refer in any depth to Kuhn or the phi-losophy of science. He took content parallels to ideas in the history of sci-ence as empirical facts, unrelated to theories of change
After reading a little about the Theory Theory concept, we know that child's everyday knowledge is developed by using everyday cognitive ability that adults use. They develop theories in their mind which sometimes help them to think harder and come up with explanations. I also read that theory theory concept help children mainly in Science, as we as adults work on problems that we could not or did not solve as kids.What I mean is that science is always a work in progress and we keep working on discovering and experimenting....Is that true? Does someone agree with me?
máquinas
El desarrollo industrial del siglo XIX y la mecanización del trabajo inspiraron muchas películas y documentales a principios del siglo XX. Quizá la más conocida sea Metrópolis, pero estas también son un buen ejemplo:
Manhatta (Charles Sheeler, 1921): es un cortometraje documental que enseña cómo era la vida en Manhattan a principios del siglo XX.
Nothing but time - Rien que les heures - (Alberto Cavalcanti, 1926): documental que expone la vida en París durante un día y una noche, durante los inicios del siglo XX.
Berlín, sinfonía de una ciudad - Die Symphonie der Großstadt - (Walter Ruttmann, 1927): es un documental basado en la vida diaria de la ciudad de Berlín, moderna e industrial, y que muestra a sus habitantes tristes y angustiados.
El hombre de la cámara - Chelovek s kino-apparatom - (Dziga Vertov, 1929): es un documental en la línea de Berlín, sinfonía de una ciudad, que expone la vida cotidiana de un día cualquiera en San Petersburgo.
Modern times (Charles Chaplin, 1936): esta película es algo posterior a las demás pero comparte características con todas. Critica una sociedad en la que el capitalismo y la mecanización industrial convierten al trabajador en homo faber, es decir, le quitan humanidad y hacen que el centro de su vida sea el trabajo.
A similar point is made by some of the participants in a discussion of peer review published in the Behavioral and Brain Sciences: An International Journal of Current Research and Theory with Open Peer Commentary (5 [1982]: 187-255). The occasion was the report of research conducted by D. P. Peters and S. J. Ceci. Peters and Ceci had taken twelve articles published in twelve different journals, altered the titles, substituted for the names of the authors fictitious names identified as researchers at institu- tions no one had ever heard of (because they were, made up), and resubmitted the articles to the jour- nals that had originally accepted them. Three of the articles were recognized as resubmissions, and of the remaining nine eight were rejected. The response to these results ranged from horror ("It puts at risk the whole conceptual framework within which we are accustomed to make observations and con- struct theories" [245]) to "so what else is new."
Peters & Ceci 1982 comes up!
τῆς δὲ προδοσίας οὐκ ἐπαύετο ἀλλὰ γράψας ἐπιστολὰς Ξέρξῃ Ἀργιλίῳ ἀγαπωμένῳ ἑαυτοῦ δίδωσι ταύτας, ἐγκελευσάμενος κομίζειν πρὸς Ξέρξην. ὁ δὲ Ἀργίλιος δεδοικὼς περὶ αὑτοῦ, ἐπειδὴ γὰρ οὐδὲ οἱ πρότεροι πεμφθέντες ἀπενόστησαν, πρὸς Ξέρξην οὐ παρεγένετο, ἐλθὼν δὲ εἰς Σπάρτην τοῖς ἐφόροις ἐμήνυσε τὴν προδοσίαν, ὑπέσχετο δὲ κατάφωρον δείξειν τὸν Παυσανίαν. καὶ συνθέμενος περὶ τούτων ἦλθεν εἰς Ταίναρον ἔν τε τῷ τοῦ Ποσειδῶνος τεμένει ( vac. 6 lines) τοῦτο ἐστιν τὸ ζη ἱκέτευεν· οἱ δὲ ἔφοροι παραγενόμενοι καὶ αὐτοὶ εἰς τὸ αὐτὸ τέμενος καὶ διπλῆν σκηνὴν κατασκευάσαντες ἐν αὐτῇ ἔκρυψαν ἑαυτούς.
FGrHist 104 procede con il racconto dei fatti riguardanti ''Argilio '' seguendo grosso modo la stessa linea di Tucidide. Ogden 2002, 124 discute la differenza tra ''un uomo di Argilio '' e ''Argilio s'' che si trova nei soli Nepote e FGrHist 104. Esso è un etnico soltanto per Tucidide. Aggiunge Ogden ''If Argilos is a proper name, a speaking one like Cleonice it means earth, clay'' e richiamerebbe le cave sotterranee del nekumanteion di Cuma che sarebbe razionalizzata da Tucidide. CulassoGastaldi 1990, 264. Non so quanto possa essere ritenuto rilevante il diverso destinatario: se è vero ciò che dice Erodoto in 8.98, per arrivare da Serse una lettera sarebbe dovuta necessariamente partire dalla Sardi di Artabazo. Comunque, πρὸς Ξέρξην di FGrHist 104 è consono a Πρὸς τὸν βασιλέα di Diod. 11.45.1 mentre hanno πρὸς Ἀρτάβαζον Thuc. 1.132.5 e Nep 4.1. Si ritrova nel nostro autore un dato molto interessante, e forse più significativo di quanto si sia ritenuto, in riferimento a Tucidide che dice di Argilio παιδικά ποτε ὢν αὐτοῦ καὶ πιστότατος ἐκείνῳ. Anche in Nep. Paus. 4.1: Argilius quidam adulescentulus, quem puerum Pausanias amore uenerio dilexerat. Si veda Vattuone 2004a, 128 per la dike non vincolante dell'erotica arcaica. In FGrHist 104, Argilio è l'amante di Pausania (ἀγαπωμένῳ ἑαυτοῦ) e di nuovo, come per la reazione spartana all'inganno di Temistocle, la versione che abbiamo davanti legge e spiega, dà la soluzione digerita e non il testo dell'informazione. Diodoro, l'altra nostra fonte al riguardo lo dice semplicemente τις τῶν βιβλιαφόρων e passa subito al problema dell'eliminazione consigliata nelle lettere tralasciando la relazione tra i due. Credo che questa notazione non possa essere sottovalutata nella lettura dell'episodio che, se ha un valore eziologico e si costruisce con le caratteristiche di un rito di evocazione, conserva un tratto evidentemente legato al nomos spartano. Ogden (Ogden 2002, 123) identifica il luogo di costruzione della ''capanna'' (καλύβην Thuc. 1.133) al capo Tanaro col nekumantheion che sarebbe stato la cava vicina al tempio di Poseidone (n.53 Strabo C636; Pausania 3.25; Pomponius Mela 2.59 (cf. 1.103); Schol. Aristoph. Acharn. 509; Seneca Hercules Furens 662-92; Statius Theb. 2.32-57 ecc.). Esercita fascino su Ogden, soprattutto la notizia di Nepote che fa scavare agli efori un buco. Dobbiamo ricordare innanzi tutto due delle caratteristiche dell'etica che regolamentava i rapporti tra erastes ed eromenoi. La prima la troviamo in Plutarco: ἔθος ἦν καὶ τοὺς νεωτέρους ὑπὸ τῶν πρεσβυτέρων ἐρωτᾶσθαι ποῦ πορεύονται καὶ ἐπὶ τί, καὶ τὸν μὴ ἀποκρινόμενον ἢ προφάσεις πλέκοντα ἐπιπλήττειν [era consuetudine che gli adulti chiedessero ai più giovani dove essi fossero diretti e per quale motivo; e che percuotessero chi non rispondeva o adduceva pretesti] (Nom. Lacon. 237b-c ). La seconda è quel ''biasimo sociale'' che colpiva a Sparta ''chiunque si fosse mostrato attratto dal corpo di un fanciullo (εἰδέτις παιδὸς σώματος ὀρεγόμενος φανείη Xen. Lacaed. Resp. 2.13), ancor peggio se era colto sul fatto (Εἴ τις φωραθείη ἁμαρτάνων Plut. Nom. Lacon. 237c). Vattuone 2004a, 103 e 223-224. Questi tre elementi caratteristici della normativa sull'erotica a Sparta si ritrovano tutti nel racconto di questi fatti fornito da FGrHist 104 che, abbiamo visto, pone l'intero problema di Pausania in termini di δίαιταν/διετίθει, cioè di comportamento abituale e sull'opposizione tra ἀναφανδὸν/διεξῄει. Riguardo a quest'ultimo, l'intera tradizione ricorda gli efori nascosti per essere αὐτήκοοι (diretti ascoltatori), fossero essi dietro una tenda costruita da loro o per loro, oppure in un buco (Ogden 2002, 124), ma solo in FGrHist 104, Argilio come Alessandro e poi Temistocle si vincola facendo una promessa. La promessa è una spiegazione semplice, una motivazione e una causa soddisfacente per un'azione, comoda per tutte le situazioni in cui è l'iniziativa personale l'elemento insondabile. Nell'ottica invece del primo punto, possiamo prendere in considerazione il nomos sopra citato come filtro per osservare la tradizione sul dialogo intercorso tra Argilio e Pausania . In Tucidide, che abbiamo visto marcare la relazione sociale tra i due, Pausania tiene un atteggiamento che può suonare melenso nei confronti di chi ne ha tradito la fiducia, virtù ricercata seppur spesso disattesa, ma è in realtà chiaramente un rimprovero, inteso nelle due fasi del ἐρωτᾶσθαι ed ἐπιπλήττειν che abbiamo visto in Plutarco. Vattuone 2004a, 130 per l'infedeltà ricorrente dei ragazzi come specchio di una crisi della polis. In un certo senso forse anche la disparità è infranta dato che Argilio era ποτε l'eromenos. Tucidide riporta il discorso di Pausania in modo indiretto ed in esso il reggente dice: περὶ τοῦ παρόντος οὐκ ἐῶντος ὀργίζεσθαι, ἀλλὰ πίστιν ἐκ τοῦ ἱεροῦ διδόντος τῆς ἀναστάσεως καὶ ἀξιοῦντος ὡς τάχιστα πορεύεσθαι. [non essere arrabbiato per il presente, ma datagli garanzia che sarebbe uscito dal tempio, chiedeva che partisse al più presto. (1.133) FGrHist 104 sinteticamente ci informa di come ἀπεμέμφετο ἐπὶ τῷ μὴ κομίσαι τὰς ἐπιστολὰς πρὸς Ξέρξην, mentre Diodoro, che aveva tralasciato il dettaglio della relazione amorosa, trasforma l'intera interlocuzione in una serie di scuse e suppliche di Pausania al portatore di lettere τοῦ δὲ Παυσανίου φήσαντος μεταμελεῖσθαι καὶ συγγνώμην αἰτουμένου τοῖς ἀγνοηθεῖσιν, ἔτι δὲ δεηθέντος ὅπως συγκρύψῃ[Pausania si scusò e chiese perdono per gli errori, e implorò affinché conservasse il segreto] (11.45.5). Resta solo l'elemento del non visibile e del segreto. Se la storia di Pausania è frutto della narrazione per motivare un pretesto avanzato prima della guerra (Thuc. 1.128.2), oppure per motivare un nomos come per il caso della legge licurgea contro l'allontanamento da Sparta, osserviamo qui invece un perdersi progressivo nella tradizione dell'originale contesto normativo, che da socio-etico diviene politico. Oltre ad essere più completo nel significato complessivo, e oltre a contenere peculiarità indipendenti (il nome del padre di Cleonice e l'hapax περίυπνος), FGrHist 104 in questo punto è coerente con la tradizione ricordata in Plutarco (Nom. Lacon. 237b-c), e Pausania sarebbe coinvolto in un caso legato ai costumi, non solo estetici e di abitudini, ma di παιδικά. L'indagine e il processo poggiano dunque su modi e termini dell'inchiesta su εἰδέτις παιδὸς σώματος ὀρεγόμενος φανείη (Xen. Lacaed. Resp. 2.13). Con questo abbiamo già due degli elementi fondativi di questo mito di Pausania che serve molte funzioni, racconta storie in tanti contesti e riporta l'attenzione sulla complessità del meccanismo di trasmissione e memoria storica, che traspare nella razionalizzazione di FGrHist 104 proprio perché non è più complicato della semplice sintesi coerente.
μετέστησαν δὲ αὐτούς οἱ Λακεδαιμόνιοι. φήσαντες Ἀθηναίους ἐμπειροτέρους εἶναι πρὸς τὸ μάχεσθαι Πέρσαις. ἐν δὲ τούτῳ Μαρδόνιος δεδοικὼς μάχεσθαι Ἀθηναίοις μετέστησέ τε τὴν φάλαγγα, καὶ οὕτως συνέβη τοῖς Λακεδαιμονίοις καὶ ἀκουσίως μάχεσθαι τοῖς Πέρσαις. Ἐστρατήγει δὲ Λακεδαιμονίων μὲν Παυσανίας ὁ Κλεομβρότου, Ἀθηναίων δὲ Ἀριστείδης ὁ δίκαιος. Γενομένης δὲ τῆς συμβολῆς τῶν Περσῶν, Ἀθηναῖοι ἐπεβοήθησαν τοῖς Λακεδαιμονίοις καὶ ἐνίκησαν.
La complessità delle manovre che precedono la battaglia in Erodoto non ha reso la vita semplice ai successivi lettori. Le truppe si trovano disposte a rovescio rispetto alle posizioni iniziali in Hdt. 9.28s.: gli Spartani alla destra greca, e i Persiani alla sinistra del loro schieramento, opposti ai Persiani i primi, ai Greci medizzanti i secondi. Queste sono le posizioni di 9.47, che è il momento dell'inizio della battaglia, e quindi ancora con l'esercito persiano schierato con i propri alla destra, cioè di fronte agli Ateniesi in questo momento. La semplificazione degli scambi da tre a due evita l'intercorrere di tempo e le alterne decisioni. Di nuovo siamo di fronte ad una riduzione della materia ai ''fatti'' che in questo caso conserva genericamente gli scambi, senza andar troppo per il sottile sulla loro natura, e sottolineando invece alcuni, precisi elementi. Il posto d'onore spetta di nuovo agli Ateniesi e si arriva a dire che gli Spartani combatterono ἀκουσίως [controvoglia], mentre dei restanti contingenti non si fa parola. Inoltre è posto l'accento sul timore dei Persiani, quando, come Serse poco prima a Salamina, Mardonio è definito δεδοικώς.
καθεζόμενος ἐπὶ τοῦ Πάρνηθος ὄρους (ἐγγὺς δὲ ἦν τοῦτο) ἑώρα τὴν ναυμαχίαν.
Jacoby si soffermava invece sul problema dell'Erakleion e sulla posizione del ''trono di Serse'' a cui sono legati numerosi aspetti della ricostruzione corografica della battaglia di Salamina.
Il fatto che Serse fosse seduto è più importante di quanto non sembri. Demostene In Timocratem (24.129) nomina un δίφρον τὸν ἀργυρόποδα rubato insieme alla spada di Mardonio (Cfr. anche Arpocrazione s.v. A 226), dalle offerte dell'acropoli e ricordato anche da Plutarco (Them. 13.1 χρυσοῦν δίφρον θέμενος; Them. 16.1 καθήμενος ὑπὸ σκιάδι χρυσῇ θεάσεται; cfr. anche _Arist. _9.5), e da Filostrato (Imagines 2.31 ἐπὶ χρυσοῦ θρόνου). La scena del re in trono non faceva solo parte dell'immaginario, ma trovava, nel dipinto di Mandrocle all'Heraion di Samo (Hdt. 4.88), una fonte plausibile e non ancora sbiadita alla fine del V secolo. Esso fu dedicato con i doni offerti da Dario in cambio della costruzione del ponte sul Bosforo e portava un'iscrizione. Questo dipinto, non certo originale nella tradizione vicino-orientale, ispira probabilmente la scena di Hdt. 7.44s. Asheri 2003, 267; Briant 1996, 234 e 939-940. Taboada 1999, 50-51, mette in evidenza come questo motivo avrà grande fortuna (tuttavia, credo, non tramite il canale greco), riportando ad esempio un passo di Tabari: ''davanti agli Arabi che avanzano, il generale Rustum posiziona il suo stato maggiore su una collina e da un trono, collocato sotto un baldacchino, si prepara a contemplare la vittoria, però quel che vede sono gli Arabi che mettono in fuga il suo esercito sassanide, si leva un forte vento che porta via il padiglione dei generali e un guerriero arabo, Hilal Ibn 'Ufalla si avventa sul baldacchino e ammazza Rustum che vorrebbe scappare'' (Tarij al rusul wa al muluk 1.2335/7); e Ibn Jaldun, sulla battaglia di Qadisiyya (637d.C.): ''Rustum stava seduto su un trono, rialzato fin che non si sbandarono le file persiane e gli Arabi avanzarono fino a quel trono. Tentò di fuggire verso l'Eufrate ma lo ammazzarono'' (Muqaddima 3.37).
For example, "they" should use more mon- ey to keep the streets safer. When asked who con- stitutes "they," the boys were sometimes able to name them as their neighbors, their police, their government, their parents, or any other group(s) that needed to take action. At other times, the "they" were unidentifiable.
this is an interesting point. The students thought somethings they wanted to see changed were even beyond the capabilities to those they look up to. I think teachers can use this to help develop students self-esteem and make they believe that one day they can be the they that can't be identified. Allow the students to see they can do anything they put their mind to.
Hoy, viernes 29 de abril, estamos compartiendo anotaciones abiertas con los colegas de #STEMmED en @sagradoedu. Saludos a tod@s, también a los participantes del #mpw2 de @hetsorg.
Jones and LeBaron p. 503: "A major current trend is to emphasize mutual or co-active influences. Although it is still common, among quantitative studies, for verbal and nonverbal behaviors to be coded as separate messages assumed to have distinct meanings, some researchers are attending to the interplay of messages between interactants, rather than merely the behaviors of one person in an interaction. Somewhat con- trived situations are often used in such studies, but the new emphasis on mutual influence contrasts with the traditional experimental approach in which a confed- erate performs certain planned behaviors in order to see the effects on the other person(s)."
ach individual creates and bears. his own image, but there see°:s to be substantial agreement among mem-bers of the same group. It is these group images, exhibiting con-set'l.sus a~ong significant numbers, that interest city planners who aspire to model an environment that will be used by many people.
Does every individual fall into some type of group?
Teaching has been reduced to the written equivalent of TV news sound bites in pan, because so many groups lobby hard for inclusion of their p et ideas Moreover, much of what they wish to be taught i s n ow taught; the problem is that it isn't learned and can't easily be, given the inert and glib quality of the text. Con tent is reducible to sound bites only when curricular lobbyists (and an alarming number of educators) be lieve that learning occurs merely by hearing or seeing the "truth." The problem of student ignorance is thus really about a dult i gnorance as to how thoughtful and long-lasting under standing is achieved
How is thoughtful and longlasting understanding achieved?
Ho w to R ead a Judicia l Opin ion: A G uid e for N ew L aw Stu den ts Professor Orin S. Kerr George Washington University Law School Washington, DC Version 2.0 (August 2005) This essay is desig ned to help entering law students understand ho w to read cas es for class. It explains what judicial opinions are, how they are structured, and what you should look for when you read them. Part I explains the various ingredients found in a typical judicial opinion, and is the most essential section of the essay . Par t II discusses what you should look for when you re ad an opinion for class. Part II I con clu des with a brief discussion of why law schools use the case method.
I need a way to add tags to a document that will apply to all annotations in a particular document (except where explicitly canceled).
The problem is that I often want to query all annotations related to a specific document, collection of documents, or type of activity.
Type of activity requires further explanation: Given a document or collection of documents I may annotate the document for different reasons at different times.
For example, while annotating the reading materials, video transcripts, and related documents for the CopyrightX course there are certain types of annotations that may be "bundled together" so that when I search for those things later I can easily narrow my searches to just that subset of annotations; but at the same time I need a way to globally group things together.
While reading judicial opinions the first activity/mode of interaction with a particular document may be to identify the structure of the judicial opinion (the document attached to this annotation describes the parts of the judicial opinion I might want to identify: *caption, case citation, author, facts of the case, law of the case, disposition, concurring and/or dissenting opinions, etc).
The above-described mode I may use for multiple documents in one session related to the course syllabus for the week.
To connect each of these documents together I might add the tags: copyx (my shorthand for the name of the course, CopyrightX), week 1 (how far into the course syllabus), foundations (the subject matter in the syllabus which may span week 1, week 2, etc), judicial opinions (the specific topic I am focused on learning at the moment (may or may not be related to the syllabus).
Later on another day I might update my existing annotations or add new ones when I am preparing to study for an exam. I might add tags like to study, on midterm, on final to mark areas I need to review.
After the exam I might add more tags based on my test score, especially focusing on areas that received a poor score so I can study that section more or, if I missed some sections so didn't study and it resulted in a poor score in that area, add tags to study for later if necessary.
I have many more examples and modes of interaction in mind that I can explain more later, but it all hinges on a rich and flexible tagging system that: