20 years Age of onset 3 years 9 years
19 Matching Annotations
- Jul 2026
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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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20 years Age of onset 3 years 9 years
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- Apr 2026
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accessmedicine.mhmedical.com accessmedicine.mhmedical.com
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Urgent treatment for neoplasm consists of (1) cautious use of intravenous diuretics and (2) mediastinal irradiation, starting within 24 hours, with a treatment plan designed to give a high daily dose of radiation but a short total course of therapy to rapidly shrink the local tumor. Intensive radiation therapy combined with chemotherapy will palliate the process in up to 90% of patients. In patients with a subacute presentation, radiation therapy alone usually suffices. Chemotherapy is added if lymphoma or small-cell carcinoma is diagnosed
endovascular stenting emerging as first-line therapy for rapid symptom relief, while definitive treatment targets the underlying cause
Tags
- When thrombosis is present, catheter-directed thrombolysis or aspiration thrombectomy should be performed within 2-5 days of symptom onset before thrombus organization occurs. [3] The role of long-term anticoagulation after stenting remains unclear, though it is standard when significant thrombosis is present
- Glucocorticoids (dexamethasone 4 mg every 6 hours) are commonly prescribed but lack robust supporting data; they may be more beneficial in lymphoma or thymoma and as prophylaxis against radiation-induced edema. [2-4] Importantly, SVC syndrome is no longer considered a medical emergency except in rare cases with life-threatening cerebral edema, laryngeal edema, or altered mental status.
- The American College of Chest Physicians recommends obtaining histologic diagnosis before treatment in suspected lung cancer cases, as stenting does not interfere with tissue diagnosis. [2] For small cell lung cancer (SCLC), chemotherapy alone is recommended as first-line treatment given rapid response rates. [2] For non-small cell lung cancer (NSCLC), radiation therapy and/or stent insertion are recommended, with response rates of 59% for chemotherapy and 63% for radiation therapy. [2] Patients with chemotherapy- or radiation-refractory disease should receive vascular stents
- For device-related thrombosis (catheters, pacemakers), catheter removal should be considered in conjunction with anticoagulation. [4] Endovascular therapy is first-line for device-related obstruction, while surgical bypass may be preferred for mediastinal fibrosis. [7] Both approaches show good mid-term patency, though secondary interventions are common (approximately 27-28%
Annotators
URL
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- Aug 2023
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www.scientificamerican.com www.scientificamerican.com
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Timmy Broderick in Evidence Undermines ‘Rapid Onset Gender Dysphoria’ Claims In Scientific American at 2023-08-24 (accessed:: 2023-08-25 09:26:00)
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As legislation targeting trans people has reached an all-time high in the U.S., ROGD’s alleged social contagion has been invoked by lawmakers in states such as Missouri, Utah and Arkansas to justify banning or restricting gender-affirming care for young people.
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- Feb 2022
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www.bmj.com www.bmj.com
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Torjesen, I. (2022). Covid-19: Peak of viral shedding is later with omicron variant, Japanese data suggest. BMJ, 376, o89. https://doi.org/10.1136/bmj.o89
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- Jan 2022
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diabetesjournals.org diabetesjournals.org
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Kamrath, C., Rosenbauer, J., Eckert, A. J., Siedler, K., Bartelt, H., Klose, D., Sindichakis, M., Herrlinger, S., Lahn, V., & Holl, R. W. (2022). Incidence of Type 1 Diabetes in Children and Adolescents During the COVID-19 Pandemic in Germany: Results From the DPV Registry. Diabetes Care, dc210969. https://doi.org/10.2337/dc21-0969
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- Dec 2021
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www.researchsquare.com www.researchsquare.com
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Chertow, Daniel, Sydney Stein, Sabrina Ramelli, Alison Grazioli, Joon-Yong Chung, Manmeet Singh, Claude Kwe Yinda, et al. ‘SARS-CoV-2 Infection and Persistence throughout the Human Body and Brain’, 28 December 2021. https://doi.org/10.21203/rs.3.rs-1139035/v1.
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www.medrxiv.org www.medrxiv.org
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Lai, J., German, J., Hong, F., Tai, S.-H. S., McPhaul, K. M., Milton, D. K., & Group, for the U. of M. S. R. (2021). Comparison of Saliva and Mid-Turbinate Swabs for Detection of COVID-19 (p. 2021.12.01.21267147). https://doi.org/10.1101/2021.12.01.21267147
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- Aug 2020
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www.thelancet.com www.thelancet.com
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Kretzschmar, M. E., Rozhnova, G., Bootsma, M. C. J., Boven, M. van, Wijgert, J. H. H. M. van de, & Bonten, M. J. M. (2020). Impact of delays on effectiveness of contact tracing strategies for COVID-19: A modelling study. The Lancet Public Health, 5(8), e452–e459. https://doi.org/10.1016/S2468-2667(20)30157-2
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www.medrxiv.org www.medrxiv.org
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Starnini, M., Aleta, A., Tizzoni, M., & Moreno, Y. (2020). Impact of the accuracy of case-based surveillance data on the estimation of time-varying reproduction numbers. MedRxiv, 2020.06.26.20140871. https://doi.org/10.1101/2020.06.26.20140871
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- Jul 2020
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www.medrxiv.org www.medrxiv.org
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Seow, J., Graham, C., Merrick, B., Acors, S., Steel, K. J. A., Hemmings, O., O’Bryne, A., Kouphou, N., Pickering, S., Galao, R., Betancor, G., Wilson, H. D., Signell, A. W., Winstone, H., Kerridge, C., Temperton, N., Snell, L., Bisnauthsing, K., Moore, A., … Doores, K. (2020). Longitudinal evaluation and decline of antibody responses in SARS-CoV-2 infection. MedRxiv, 2020.07.09.20148429. https://doi.org/10.1101/2020.07.09.20148429
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- Jun 2020
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jamanetwork.com jamanetwork.com
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Cheng, H.-Y., Jian, S.-W., Liu, D.-P., Ng, T.-C., Huang, W.-T., Lin, H.-H., & for the Taiwan COVID-19 Outbreak Investigation Team. (2020). Contact Tracing Assessment of COVID-19 Transmission Dynamics in Taiwan and Risk at Different Exposure Periods Before and After Symptom Onset. JAMA Internal Medicine. https://doi.org/10.1001/jamainternmed.2020.2020
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- May 2020
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www.thelancet.com www.thelancet.com
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Rybniker, J., & Fätkenheuer, G. (2020). Importance of precise data on SARS-CoV-2 transmission dynamics control. The Lancet Infectious Diseases, S1473309920303595. https://doi.org/10.1016/S1473-3099(20)30359-5
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www.thelancet.com www.thelancet.com
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Ghinai, I., McPherson, T. D., Hunter, J. C., Kirking, H. L., Christiansen, D., Joshi, K., Rubin, R., Morales-Estrada, S., Black, S. R., Pacilli, M., Fricchione, M. J., Chugh, R. K., Walblay, K. A., Ahmed, N. S., Stoecker, W. C., Hasan, N. F., Burdsall, D. P., Reese, H. E., Wallace, M., … Uyeki, T. M. (2020). First known person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the USA. The Lancet, 395(10230), 1137–1144. https://doi.org/10.1016/S0140-6736(20)30607-3
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academic.oup.com academic.oup.com
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Li, W., Zhang, B., Lu, J., Liu, S., Chang, Z., Cao, P., Liu, X., Zhang, P., Ling, Y., Tao, K., & Chen, J. (2020). The characteristics of household transmission of COVID-19. Clinical Infectious Diseases, ciaa450. https://doi.org/10.1093/cid/ciaa450
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- Apr 2020
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www.nature.com www.nature.com
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Among the people who died from COVID-19 reported by the NHC, 11.8% of patients without underlying CVD had substantial heart damage, with elevated levels of cTnI or cardiac arrest during hospitalization.
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some of the patients first went to see a doctor because of cardiovascular symptoms. The patients presented with heart palpitations and chest tightness rather than with respiratory symptoms, such as fever and cough, but were later diagnosed with COVID-19.
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- Jan 2019
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wendynorris.com wendynorris.com
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The use of social time may also give us a unique view on understanding slow moving disasters (e.g., environmental events, famines and droughts) when compared to sudden impact events. Social time and social disruption provides tools to define disaster without making assessments (i.e., good/bad) of the event.
Neal also contends that time embedded in the disaster onset (sudden vs slow) is a better heuristic for studying these events.
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wendynorris.com wendynorris.com
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He adds that this phase could be important with sudden impacts, but not as important with slow-moving impacts.
Barton's definition of disaster phases (1970) includes event temporality: slow-moving vs sudden.
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