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Figure 1 here is particularly important.

Set of minimal conditions together define the sufficient cause or complete causal mechanism.

The expression, "without which the disease or event would not have occurred", points out to another important concept here, the notion of counterfactual theory of causation.

Note the criteria:

1. Cause as an event
2. Cause as a condition
3. Cause as characteristic
4. Cause is antecedent
5. Cause is necessary
6. Cause is conditional We will see all of these conditions expanded

Note that we start with the example of the bulb and then expand to generalise this example to larger issues -- in our case, health.

Another important point -- often the last observable event tends to be considered the "cause" of an outcome. One must be careful to find out other possible causes of an outcome.

This is a very important point in this paper. It points to the notions of multifactorial causality -- that is, an outcome will more often than not have more than one cause, and one cause is not usually sufficient to result in the effect.