§ 103. Recall Any elected official or official appointed to elective office holding a Town office may be recalled by the following process: (1) A petition signed by not less than 35 percent of the number of registered voters voting in the last annual Town meeting shall be filed with the Town Clerk. (2) The petition shall request a special Town meeting for the purpose of recalling a specific person or persons and shall state the office that they hold. (3) The Selectboard shall act upon the petition within seven days by warning a special Town meeting. (4) The Town meeting shall be held not less than 30 days and not more than 40 days from the date of the receipt of the petition. (5) The special Town meeting shall be warned as provided by the general law of this State. (6) At least four days but not more than 15 days prior to the voting, an informational meeting shall be held at which time both the elected official and the proponents for the recall shall have the opportunity to discuss the issue of recall. The informational meeting shall be warned in conjunction with the warning for the special Town meeting. (7) Voting on the issue of recall shall be by Australian ballot. A majority of the legal votes cast shall be needed to effect a recall of that official.
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La Bienveillance en Milieu Scolaire : Enjeux, Défis et Pratiques Professionnelles
Résumé Exécutif
Ce document synthétise les échanges issus d'une table ronde portant sur le concept de bienveillance à l'école.
Loin d'être synonyme de laxisme ou de complaisance, la bienveillance est définie comme une condition essentielle de l'équité et de l'efficacité du système éducatif, particulièrement pour les élèves les plus vulnérables.
Elle repose sur une tension constructive entre exigence et soutien, visant le développement à long terme de l'élève.
Sa mise en œuvre nécessite une clarification conceptuelle pour lever les résistances professionnelles, l'adoption de gestes professionnels spécifiques (feedback positif, écoute active) et une réinvention des espaces et des modalités d'évaluation.
En somme, la bienveillance est un levier de réussite qui engage tant la posture individuelle de l'enseignant que la stratégie collective de l'établissement.
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1. Définition et Clarification Conceptuelle
La bienveillance en éducation souffre souvent de représentations simplistes ou erronées. Il est nécessaire d'en préciser les contours épistémologiques :
• Étymologie et intention : Littéralement, la bienveillance consiste à « vouloir du bien à autrui ».
C'est une disposition favorable qui vise la réussite et la réalisation personnelle de l'autre.
• Temporalité (Court terme vs Long terme) : La bienveillance peut impliquer de sacrifier le confort immédiat pour le bien de l'élève à long terme.
Ainsi, la fermeté, l'exigence ou même une sanction peuvent être des actes bienveillants s'ils sont explicités et pratiqués dans le respect de l'élève.
• Distinction fondamentale : Elle ne doit pas être confondue avec :
- ◦ Le laxisme.
- ◦ La complaisance.
- ◦ La mansuétude.
• Cadre institutionnel : La notion est devenue une valeur centrale de l'Éducation nationale depuis la circulaire de 2014, bien qu'elle fût déjà présente dans le secteur privé et les services publics.
La DGESCO (2013) l'associe à un ensemble d'attitudes physiques, morales et psycho-affectives positives et constantes (respect, confiance, encouragement).
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2. Analyse des Résistances Professionnelles
Malgré un consensus apparent, le terme suscite des tensions sur le terrain :
| Type de résistance | Argumentation observée | | --- | --- | | Sentiment de jugement | Certains enseignants perçoivent l'injonction à la bienveillance comme une critique de leurs pratiques passées, sous-entendant qu'ils ne l'auraient pas été auparavant. | | Opposition à l'exigence | Une crainte que l'attention portée au bien-être des élèves ne se fasse au détriment de l'effort nécessaire à la réussite académique. | | Crise de l'autorité | La bienveillance est parfois vue comme une entrave à l'autorité face à des manquements disciplinaires chroniques. | | Complexité systémique | La multiplication des élèves à besoins éducatifs particuliers (EBEP) met les équipes sous pression, rendant la posture bienveillante difficile à maintenir sans formation adéquate. |
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3. Les Gestes Professionnels de la Bienveillance
La bienveillance se traduit par des actes concrets et une posture éthique dans la relation pédagogique :
La puissance du Feedback
Le levier le plus efficace pour la réussite des élèves est le feedback positif. Il doit être :
• Centré sur l'activité et la méthodologie de l'élève.
• Formulé chaleureusement.
• Porteur de confiance et d'espoir dans les capacités de l'élève.
L'attention aux signaux de vulnérabilité
Le professionnel bienveillant doit être attentif aux signes de fragilité qui peuvent mener au décrochage :
• Signes de découragement ou discours négatif sur l'école.
• Absentéisme et arythmies.
• Sentiments d'insécurité (peur de prendre la parole, honte).
• Mutisme, isolement ou passages fréquents à l'infirmerie/vie scolaire.
Une communication renouvelée
L'horizontalité et l'authenticité sont cruciales pour les nouvelles générations :
• Passer d'un rôle purement académique à une relation de personne à personne.
• Pratiquer l'écoute active (savoir se taire pour laisser l'élève s'exprimer).
• Faire preuve de transparence et de prévisibilité.
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4. Domaines d'Application et Leviers d'Action
L'Évaluation comme espace de sécurisation
L'évaluation est une source majeure de stress (environ 60 % des élèves se disent angoissés par les évaluations). Une évaluation bienveillante implique :
• La suppression de l'implicite.
• Le droit à l'erreur et à la remédiation (possibilité de recommencer).
• Un cadre rassurant qui ne sacrifie pas l'exigence intellectuelle.
La lutte contre le harcèlement (Programme PHARE)
La bienveillance s'incarne dans la création d'une « communauté protectrice » :
• Utilisation de la méthode de la « préoccupation partagée ».
• Recherche d'alternatives à la sanction punitive immédiate pour l'intimidateur, en visant le développement de compétences psychosociales.
La transformation des espaces
La bienveillance passe par une réflexion sur le cadre de vie :
• Création de « jardins zen » ou de salles de calme.
• Réinvention des salles d'étude (espaces de coworking, possibilité de travailler debout ou dans des fauteuils).
• Mise en place de dispositifs permettant le mouvement (ballons, vélos-bureaux) pour favoriser la concentration, notamment des élèves hyperactifs.
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5. Éthique et Pilotage : La Bienveillance Collective
La bienveillance ne doit pas être une initiative isolée mais une stratégie d'établissement.
• Le rôle du diagnostic : Utiliser l'auto-évaluation (domaine du climat scolaire et du bien-être) pour identifier les besoins réels des élèves et des familles, en évitant les solutions préconçues.
• La Qualité de Vie au Travail (QVT) : Il existe un lien direct entre le bien-être des personnels et celui des élèves. Un encadrement bienveillant (feedback positif du chef d'établissement, convivialité, confiance déléguée) favorise l'engagement des équipes.
• L'éthique de la rencontre : S'intéresser à la singularité de ce que vit l'élève, au-delà de ses difficultés scolaires. Comme le souligne la sociologie, l'éducation par la rencontre est un levier de raccrochage puissant.
• Le partage et la convivialité : Des actions simples, comme le partage de nourriture (fruits en libre-service, repas de Noël partagé entre agents, élèves et chefs étoilés), peuvent transformer radicalement la relation sociale au sein d'un établissement.
Conclusion sur l'autorité bienveillante
L'autorité et la bienveillance sont compatibles. L'autorité s'exerce de manière éthique lorsqu'elle respecte l'intégrité morale de l'élève.
La sincérité de l'adulte, y compris dans l'expression de ses propres limites ou l'admission d'une erreur, renforce paradoxalement sa légitimité auprès des jeunes.
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eLife Assessment
This study reports an important and novel finding that TENT5A, an enzyme involved in fine-tuning poly(A) tail length on selected mRNAs, is required for proper enamel mineralization in mice. The evidence supporting the authors' conclusion that reduced expression of enamel matrix proteins (EMPs) in TENT5A-deficient mice results from shortened poly(A) tails remains incomplete, as TENT5A may possess additional functions independent of post-transcriptional regulation that are not addressed in the current study.
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Reviewer #1 (Public review):
Summary:
The authors aim to determine whether TENT5A, a post-transcriptional regulator previously implicated in bone formation, also plays a role in enamel development. Using a mouse model lacking TENT5A, they report hypomineralized enamel with structural defects, accompanied by reduced expression, altered poly(A) tail length, and impaired secretion of enamel matrix proteins, particularly amelogenin. By combining ultrastructural imaging, transcriptomics, direct RNA sequencing, and protein localization analyses, the study proposes that TENT5A promotes cytoplasmic polyadenylation and translation of a subset of extracellular matrix transcripts required for enamel biomineralization.
Strengths:
A major strength of this work is its conceptual novelty. To my knowledge, this is the first study to demonstrate that a non-canonical poly(A) polymerase plays a direct role in enamel development, extending post-transcriptional regulation by cytoplasmic polyadenylation from bone to enamel, a biologically distinct and non-regenerative mineralized tissue. The identification of amelogenin as a dominant, tissue-specific target provides a new perspective on how enamel matrix production is regulated beyond transcriptional control.
In addition, the study is supported by a comprehensive and complementary set of approaches linking molecular changes to tissue-level phenotypes. The use of direct RNA sequencing provides strong evidence for selective regulation of poly(A) tail length in specific transcripts rather than global effects on mRNA metabolism, and the phenotypic analyses convincingly connect altered post-transcriptional regulation to defects in enamel structure and mineralization.
Weaknesses:
Although the data support a role for TENT5A in stabilizing and promoting translation of amelogenin and related transcripts, the mechanism underlying substrate specificity remains unresolved. Poly(A) tail length alone does not explain why certain transcripts are regulated while others are not, and the proposed involvement of protein partners or RNA processing steps remains speculative. This limitation should be more clearly framed as an open question rather than an emerging mechanism.
A further limitation is the lack of direct human genetic or clinical evidence linking TENT5A to enamel defects. In humans, loss-of-function variants in TENT5A are known to cause a recessive form of osteogenesis imperfecta, but TENT5A has not been associated with amelogenesis imperfecta or other enamel phenotypes. This limits immediate translational interpretation of the mouse enamel phenotype and highlights the need for future human genetic or clinical studies.
Finally, the manuscript does not address whether other members of the TENT5 family are expressed in ameloblasts or could compensate for the loss of TENT5A, leaving open questions about redundancy and specificity within this family.
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Reviewer #2 (Public review):
Summary:
The manuscript by Aranaz-Novaliches describes a study of Tent5a knockout (KO) mice. The authors demonstrate a severe enamel phenotype in these mice, characterized by hypoplastic enamel with markedly disturbed organization of enamel rods. Additionally, they report that Amelx expression is reduced in the mutant compared to wild type (WT) at both mRNA and protein levels. The authors also examine the distribution and co-localization of Amelx and Ambn in ameloblasts and the enamel matrix. These findings are novel and provide important insights into the role of polyadenylation in regulating enamel matrix protein translation and its downstream effects on protein trafficking, secretion, and enamel formation. However, I have multiple concerns regarding the data and its analysis that need to be addressed.
Specific comments:
(1) Introduction
The structure of the introduction is unconventional. The first sentence of the third paragraph states that the goal of this study is to investigate the role of TENT5A in enamel formation, but the rest of the paragraph focuses on enamel in general. The following paragraph claims that the authors discovered the effects of Tent5a deficiency on enamel formation for the first time, yet most of the paragraph discusses enamel proteins and amelogenesis. The choice of references is problematic. The authors cite Sire et al. (2007), which focuses on the origin and evolution of enamel mineralisation genes, a poor fit for this context. A more appropriate source would be a recent review, e.g., Lacruz R et al., Physiol Rev. 2017;97(3):939-993. Ambn constitutes ~5% of the enamel matrix, not 10%. Reference 16 (Martin) is not ideal for murine enamel; more detailed studies exist, e.g., Smith CE et al., J Anat. 2019;234(2):274-290. References on protein-protein interactions (17-19) are also off: Wald et al. studied Ambn-Ambn and Amelx-Amelx interactions separately; Fang et al. focused on Amelx self-assembly only; Kawasaki and Weiss addressed gene evolution. The authors should cite work from Moradian-Oldak's lab, which clearly demonstrates Amelx-Ambn interactions. The last paragraph contains confusing statements, e.g., "TENT5a localized in rER promotes the expression of AmelX and other secreted protein transcripts." Also, the manuscript does not convincingly show disruption of self-assembly beyond overall enamel disorganization.
(2) Results
(a) microCT
Quantitative microCT analyses of WT and KO enamel are needed. At a minimum, enamel thickness and density should be measured from at least three biological replicates per genotype. Severe malocclusion in KO mice is not discussed. The mandibular incisor appears abraded, while the maxillary incisor is overgrown. Is maxillary enamel as affected as mandibular? The age of the mice is not specified. High-resolution scans of isolated mandibular incisors described in Materials and Methods should be included.
(b) SEM
The term "disorganized crystal structure" is incorrect - SEM cannot reveal crystal structure. This requires electron/X-ray diffraction or vibrational spectroscopy. Likely, the authors meant disorganized rods and interrod enamel. The phrase "weak HAP composition" is unclear. Can the increase in interprismatic matrix volume and reduction in rod diameter be quantified? Since rods are secreted by distal Tomes' processes and interrod by proximal Tomes' processes, an imbalance may indicate alterations in the ameloblast secretory apparatus. TEM studies of demineralized incisors are recommended to assess ameloblast ultrastructure.
(c) EMP expression
There is a discrepancy between WB images and data in Figure S2a. In Figure 2b, Amelx band is stronger than Ambn (expected, as Amelx is ~20× more abundant), but in Figure S2a, Ambn appears higher. How was protein intensity in Fig. S2a calculated? Optical density? Was normalization applied? Co-localization in Figure 2d was performed on LS8 cells, which lack a true ameloblast phenotype. Amelx expression in LS8 cells is ~2% of actin (Sarkar et al., 2014), whereas in murine incisors, it is ~600× higher than actin (Bui et al., 2023). Ambn signal is weaker than Amelx, which may affect co-localization results.
(d) Splicing products in Figure 2e
All isoforms except one contain exon 4. The major functional splice product of Amelx lacks exon 4 (Haruyama et al. J Oral Biosci. 2011;53(3):257-266), and there are some indications that the presence of exon 4 can lead to enamel defects. Can it be that the observed phenotype is due to the presence of exon 4?
(e) Co-localization studies
The presented co-localization studies do not demonstrate self-assembly defects; they reflect enamel microstructural defects observed by SEM. Self-assembly occurs at the nanoscale and cannot be assessed by light microscopy except with advanced optical methods. Conclusions based on single images are weak. The authors should perform experiments at least on three biological replicates per genotype, quantify results (e.g., total gray values per ROI of equal pixel size), and use co-localization metrics such as Mander's coefficient. Claims about alternative secretory pathways require much stronger evidence.
The authors should avoid implying that mRNA is inside the ER lumen. It is likely associated with the outer rER surface, which is expected. The resolution of the methods used is insufficient to confirm ER lumen localization.
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Reviewer #3 (Public review):
Summary:
It is well established that poly(A) tails at the 3' end of mRNA are critical for mRNA stability, providing another layer of gene regulation. TENT5A is one of the non-canonical poly(A) polymerases that add an extra poly(A) tail. This manuscript demonstrates that the Tent5A mutation leads to mineralization abnormalities in the tooth, shorter poly(A) tails in amelogenin mRNA and some other selected mRNAs, and provides a list of TENT5A interacting proteins.
Strengths:
(1) The authors show in vivo genetic evidence that Tent5a is critical for normal tooth mineralization.
(2) The authors show that the length of the poly(A) tail in amelogenin (AmelX) is 13 bases shorter in Tent5a mutants but not in other mRNAs, such as ameloblastin (Ambn).
(3) Differentially expressed genes (DEGs) in Tent5A mutant tissues (cervical loop) are identified, and some of them show different lengths of poly(A) tails.
(4) TENT5A interacting proteins are identified. Together with the DEGs, these datasets will provide valuable research tools to the community.
Weaknesses:
(1) There is no direct evidence to support the main conclusion; the length of the poly(A) tail is critical for normal tooth mineralization.
(2) The RNAseq data to identify TENT5A substrate is based on the assumption that shorter poly(A) tailed RNA is less stable. However, there are multiple reasons for the differential expression of RNA in Tent5A mutant tissues.
(3) Several TENT5A-interacting proteins have been identified, but, beyond their colocalization with a target mRNA, no mechanistic studies have been conducted.
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Author response:
We thank the editors and reviewers for their careful and constructive evaluation of our manuscript. We appreciate the recognition of the conceptual novelty and in vivo relevance of our findings. We have carefully considered all comments and outline below the major revisions and additional analyses we will undertake. For clarity, we address the reviewers’ comments in thematic sections.
Cell-autonomous contribution of Tent5a to phenotype
We agree that the use of a complete knockout model raises the possibility of indirect or non-cell-autonomous effects on tooth development, particularly given the observed dentin alterations. To address this point directly, we are generating and analyzing an ameloblast-specific conditional model we have already on shelf (Ambn-Cre; Tent5a<sup>flox/flox</sup>) to determine whether the enamel phenotype arises from cell-autonomous loss of TENT5A in the secretory epithelium. This approach will allow us to distinguish epithelial-intrinsic effects from potential secondary contributions of odontoblasts or mesenchymal tissues. Results from this model will be incorporated into the revised manuscript.
Mechanistic basis and substrate specificity
We agree that the mechanism underlying substrate selectivity of TENT5A requires further clarification. We have performed multiple classical RNA–protein interaction assays, including CLIP-based approaches, without identifying a clear sequence-specific recognition motif. In the revised manuscript, we will present substrate specificity as an open mechanistic question rather than implying a defined recognition mechanism.
To strengthen this aspect, we will extend our analysis to include combined immunoprecipitation strategies and investigation of potential ribosome-associated or co-translational interactions of TENT5A.
In addition, we will further validate selected high-confidence TENT5A interactors identified in our dataset in context of putative changes in AmelX-polyA tail length.
Poly(A) tail length and functional causality
We acknowledge that shortening of the poly(A) tail alone does not formally establish causality. However, our data consistently show that TENT5A-dependent shortening of poly(A) tails correlates with reduced mRNA and protein levels of key enamel matrix components. In the revised manuscript, we will clarify this mechanistic framework more explicitly, integrating poly(A) length, transcript abundance, and protein-level data in a structured manner, while clearly distinguishing correlation from formal proof of causality.
We will also perform additional functional assays, including mRNA stability measurements in vitro in cells with genetic ablation of Tent5a, to further test the link between poly(A) shortening and reduced AmelX protein levels.
Quantitative microCT and enamel morphology
We will include quantitative microCT analyses of enamel thickness and mineral density from multiple biological replicates per genotype (n ≥ 3). Sample numbers will be explicitly stated throughout. Additional high-resolution scans of isolated incisors will be provided. We will also quantify occlusal angle and include whole-skull reconstructions to document malocclusion. Maxillary enamel will be analyzed and quantified alongside mandibular enamel.
SEM terminology will be corrected (e.g., replacing “crystal structure” with “rod/interrod organization”), and structural parameters such as rod diameter and interprismatic matrix proportion will be quantitatively assessed.
We agree that ultrastructural analysis of ameloblast secretory morphology is important. We have experience with TEM analysis of demineralized incisors and will perform additional ultrastructural examination to assess the integrity of Tomes’ processes and the secretory apparatus in Tent5a-deficient ameloblasts. These data will allow us to distinguish between primary alterations in secretory morphology and downstream effects on matrix organization.
Amelx splice variants
We will re-analyze our RNA-seq data with specific attention to exon 4-containing isoforms and clarify the distribution of splice variants in WT and KO samples. These findings will be explicitly discussed in the context of prior literature.
Co-localization and self-assembly claims
We agree that conventional light microscopy cannot directly resolve nanoscale self-assembly events. In Figure 3, our intention was to demonstrate differential subcellular distribution and partial segregation of AMELX and AMBN within secretory compartments, rather than to claim direct visualization of molecular self-assembly. In the revised manuscript, we will clarify this distinction, moderate the terminology accordingly, and provide explicit quantitative co-localization analyses across multiple biological replicates.
TENT5 family paralogs
To address potential redundancy within the TENT5 family, we will analyze published single-cell RNA-seq datasets (Sharir et al., 2019; Krivanek et al., 2020) to assess expression of TENT5 paralogs in ameloblasts. These findings will be validated using targeted transcriptional analyses.
Human clinical relevance
We appreciate the suggestion to examine potential human enamel phenotypes. We will pursue retrospective analysis of clinical and imaging data from patients carrying TENT5A variants through our collaborations with rare disease networks and specialized centers in Europe and the United States. Any relevant findings will be incorporated into the revised manuscript.
Tissue sampling clarification
We apologize for imprecise terminology regarding transcriptomic sampling. The analyzed tissue corresponds to the proximal incisor region up to the mineralization stage. We will include a schematic and clarify nomenclature throughout the manuscript.
Language and data clarity
The manuscript will be thoroughly revised for clarity, consistency of terminology, figure referencing, and accuracy of citations. We will explicitly clarify the methodology used for protein quantification, including normalization strategy and densitometric analysis, to address inconsistencies noted in the supplementary data. We will also expand the discussion to address the biological relevance of moderate poly(A) shortening, referencing established literature demonstrating that even subtle changes in tail length can significantly influence translational efficiency.
Although AMELX is the most abundant enamel matrix protein and exhibits a consistent TENT5A-dependent poly(A) shortening phenotype, our data demonstrate that multiple secreted proteins are similarly affected. We will revise the text to clearly articulate that the enamel phenotype likely reflects the combined contribution of multiple TENT5A-regulated secretory factors rather than a single-gene effect.
We believe these revisions will substantially strengthen the mechanistic, quantitative, and conceptual framework of the study and provide a clearer foundation for interpreting TENT5A-dependent regulation of enamel biomineralization.
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Note de Synthèse : Les Enjeux de la Professionnalité Enseignante et de l'Éthique Relationnelle
Résumé Analytique
Ce document synthétise les interventions du webinaire du 12 avril 2023, animé par Christophe Marsollier, Inspecteur général de l'éducation, du sport et de la recherche.
L'analyse explore la mutation profonde du métier d'enseignant face à la complexité croissante du milieu scolaire. Les points de bascule majeurs identifiés incluent l'intégration systémique des compétences psychosociales (CPS), l'adoption de pédagogies institutionnelles et coopératives, et le passage d'une posture de « sachant » à celle d'« écoutant ».
La réussite de l'élève est ici pensée non seulement par la transmission académique, mais par une « éthique relationnelle » fondée sur la confiance, la reconnaissance de la vulnérabilité et le bien-être eudémonique.
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I. Les Compétences Psychosociales (CPS) : Socle de la Réussite et de l'Équilibre
Le développement des CPS n'est plus considéré comme une activité périphérique, mais comme la « trame de fond » de la réussite scolaire et de la santé mentale.
1. Définition et Objectifs
Les CPS englobent les capacités permettant à l’élève de :
• Gérer ses émotions : Appréhender son ressenti et celui d'autrui.
• S'auto-réguler : Gérer les conflits en autonomie et appartenir au groupe.
• Développer sa citoyenneté : Favoriser le dialogue, l’échange et la collaboration.
2. Impact sur la Pratique de Classe
Les témoignages d'enseignants (notamment du réseau Jean Lolive à Pantin) soulignent une transformation concrète :
• Apaisement du climat : Moins de besoin de « faire le gendarme » ; les élèves règlent les conflits en amont.
• Disponibilité cognitive : Des élèves sereins et empathiques sont plus aptes à entrer dans les apprentissages pédagogiques.
• Transformation de l'enseignant : Le passage d'un scepticisme initial à une confiance réelle en la capacité d'agir des élèves.
3. Institutionnalisation et Formation
Une instruction interministérielle, rédigée par Santé Publique France, fixe un horizon à 2037 pour la formation généralisée de la population aux CPS.
• Cadre de référence : Publication d'un référentiel en février 2022 pour uniformiser les pratiques.
• Pédagogies préconisées : Utilisation de méthodes expérientielles comme le « théâtre forum » ou le « jeu des trois figures » pour favoriser le changement de rôle et l'empathie.
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II. Pédagogie Institutionnelle et Autonomie de l'Élève
L'analyse met en lumière la pédagogie institutionnelle (PI) comme levier de transformation, particulièrement en éducation prioritaire (REP+).
1. Le Système des « Ceintures d'Apprentissage »
Inspiré du mouvement Freinet, ce dispositif permet d'articuler éducation (épanouissement) et transmission (connaissances).
| Caractéristique | Fonctionnement et Bénéfices | | --- | --- | | Différenciation | L'élève choisit son niveau de ceinture par compétence (ex: se repérer dans le temps). | | Auto-évaluation | Utilisation de fichiers autocorrectifs ; l'élève identifie ses stratégies d'apprentissage. | | Évaluation Positive | La ceinture sanctionne la réussite (100% requis) et non le manque. L'échec est une étape formative. | | Coopération | Les élèves ayant validé des ceintures deviennent des « aides » pour leurs pairs. |
2. Les Institutions de la Classe
La classe est pensée comme une « petite société » régulée par :
• Le Conseil : Lieu de décision collective où l'on critique l'organisation et propose des améliorations.
• Les Responsabilités : Métiers spécifiques (responsable du temps, du matériel, des affichages) qui donnent une place à chacun.
• L'Espace de parole : Le « Quoi de neuf » et les temps de météo intérieure pour intégrer les affects.
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III. La Métaphore du Tisseur : Penser la Complexité
Le métier d'enseignant est comparé à celui d'un tisseur, créateur de liens et de sens dans un monde « déchiré ».
1. La Triple Reliance
S'appuyant sur les travaux d'Edgar Morin et d'Adrien Rivard, Christophe Marsollier évoque la nécessité de cultiver :
- 1. La reliance à soi : Apprendre à se connaître et à être présent à ses propres émotions.
- 2. La reliance aux autres : Développer des relations saines et authentiques.
- 3. La reliance à la nature : Répondre à l'anxiété climatique des jeunes générations par un retour à l'essentiel.
2. Les Quatre Réciprocités Fondamentales
Pour maintenir le « tissu » de la relation pédagogique, quatre piliers sont identifiés :
• La Confiance : Elle doit être mutuelle et engagée.
• Le Respect : L'élève doit être considéré comme une personne à part entière, avec sa dignité propre.
• L'Écoute : Sortir de l'écoute passive pour une écoute active des difficultés et erreurs.
• Le Droit à l'erreur : Admis pour l'élève, mais aussi pour l'enseignant qui doit pouvoir s'excuser.
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IV. Vulnérabilité et Éthique de l'Accompagnement
L'enseignement, particulièrement en milieu défavorisé, exige une attention particulière à la vulnérabilité des élèves.
• La Blessure Psychologique : Les élèves en grande vulnérabilité sont souvent touchés dans leurs besoins fondamentaux (sécurité, reconnaissance, justice).
• L'Intérêt pour la Singularité : Les recherches (Virginie Muniglia) montrent que le besoin premier des jeunes vulnérables est que l'adulte s'intéresse à leur singularité, et non qu'il les traite de manière standardisée.
• Le Tact Pédagogique : Capacité (théorisée par Éric Prairat) à trouver le bon geste et le bon mot au bon moment, en s'adaptant à l'imprévu.
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V. Vers une Redéfinition du Bien-être à l'École
Le document clarifie la notion de bien-être, souvent mal comprise dans le cadre scolaire.
1. Bien-être Hédonique vs Eudémonique
• Bien-être Hédonique : Recherche du plaisir immédiat (souvent critiqué à l'école).
• Bien-être Eudémonique : Sentiment de satisfaction ressenti lorsqu'on est captivé par une activité, qu'on dépasse une difficulté ou que l'on progresse.
C'est le « bien-être optimal » ou l'expérience autotélique.
2. Le Bien-être comme Condition, non comme Finalité
Le bien-être n'est pas le but ultime de l'école, mais la condition indispensable pour favoriser la réussite, notamment pour les élèves les plus fragiles.
Il permet de transformer la « souffrance relationnelle » en un climat d'exigence bienveillante.
--------------------------------------------------------------------------------
VI. Perspectives pour la Professionnalité Enseignante
En conclusion, le métier d'enseignant est décrit comme une profession de la relation, nécessitant :
• Le Travail Collectif : Créer des communautés d'apprentissage professionnel pour rompre l'isolement et penser la pratique (monographies, analyses de pratiques).
• La Foi en l'Éducabilité : Posture philosophique (Philippe Meirieu) consistant à croire inconditionnellement en la capacité de chaque élève à progresser.
• La Joie comme Boussole : Pour les jeunes enseignants, le critère de la joie et de l'alignement personnel est présenté comme le meilleur garant de la créativité et de l'efficacité pédagogique.
« La question n'est pas quel monde laisserons-nous à nos enfants, mais quels enfants laisserons-nous au monde. » — Philippe Meirieu (cité en conclusion).
Tags
Annotators
URL
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en.wikipedia.org en.wikipedia.org
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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
-
RRID:CVCL_1258
DOI: 10.1158/0008-5472.CAN-25-2086
Resource: (KCB Cat# KCB 2014032YJ, RRID:CVCL_1258)
Curator: @evieth
SciCrunch record: RRID:CVCL_1258
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RRID:CVCL_0553
DOI: 10.1158/0008-5472.CAN-25-2086
Resource: (RRID:CVCL_0553)
Curator: @evieth
SciCrunch record: RRID:CVCL_0553
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RRID:CVCL_YI68
DOI: 10.1158/0008-5472.CAN-25-2086
Resource: None
Curator: @scibot
SciCrunch record: RRID:CVCL_YI68
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RRID:CVCL_0598
DOI: 10.1158/0008-5472.CAN-25-2086
Resource: (ATCC Cat# CRL-10317, RRID:CVCL_0598)
Curator: @scibot
SciCrunch record: RRID:CVCL_0598
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RRID:CVCL_0062
DOI: 10.1158/0008-5472.CAN-25-2086
Resource: (RRID:CVCL_0062)
Curator: @scibot
SciCrunch record: RRID:CVCL_0062
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RRID:CVCL_0179
DOI: 10.1158/0008-5472.CAN-25-2086
Resource: (RRID:CVCL_0179)
Curator: @scibot
SciCrunch record: RRID:CVCL_0179
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RRID:CVCL_0031
DOI: 10.1158/0008-5472.CAN-25-2086
Resource: (NCI-DTP Cat# MCF7, RRID:CVCL_0031)
Curator: @scibot
SciCrunch record: RRID:CVCL_0031
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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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Addgene # 133861
DOI: 10.1111/febs.70278
Resource: RRID:Addgene_133861
Curator: @evieth
SciCrunch record: RRID:Addgene_133861
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RRID:CVCL_0030
DOI: 10.1111/febs.70278
Resource: (ICLC Cat# HTL95023, RRID:CVCL_0030)
Curator: @evieth
SciCrunch record: RRID:CVCL_0030
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Addgene_105688
DOI: 10.1111/febs.70278
Resource: RRID:Addgene_105688
Curator: @scibot
SciCrunch record: RRID:Addgene_105688
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Addgene_105686
DOI: 10.1111/febs.70278
Resource: RRID:Addgene_105686
Curator: @scibot
SciCrunch record: RRID:Addgene_105686
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RRID:CVCL_0063
DOI: 10.1111/febs.70278
Resource: (RRID:CVCL_0063)
Curator: @scibot
SciCrunch record: RRID:CVCL_0063
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Addgene_109014
DOI: 10.1111/febs.70278
Resource: RRID:Addgene_109014
Curator: @scibot
SciCrunch record: RRID:Addgene_109014
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RRID:AB_2616025
DOI: 10.1111/febs.70278
Resource: (Cell Signaling Technology Cat# 11815, RRID:AB_2616025)
Curator: @scibot
SciCrunch record: RRID:AB_2616025
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RRID:AB_627695
DOI: 10.1111/febs.70278
Resource: (Santa Cruz Biotechnology Cat# sc-9996, RRID:AB_627695)
Curator: @scibot
SciCrunch record: RRID:AB_627695
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RRID:AB_330713
DOI: 10.1111/febs.70278
Resource: (Cell Signaling Technology Cat# 9212, RRID:AB_330713)
Curator: @scibot
SciCrunch record: RRID:AB_330713
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RRID:AB_11145466
DOI: 10.1111/febs.70278
Resource: (Abcam Cat# ab128995, RRID:AB_11145466)
Curator: @scibot
SciCrunch record: RRID:AB_11145466
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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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Addgene #112865
DOI: 10.1038/s44321-025-00369-2
Resource: RRID:Addgene_112865
Curator: @evieth
SciCrunch record: RRID:Addgene_112865
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CRL-3216
DOI: 10.1038/s44321-025-00369-2
Resource: (RRID:CVCL_0063)
Curator: @evieth
SciCrunch record: RRID:CVCL_0063
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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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RRID:SCR_023747
DOI: 10.1038/s44321-025-00364-7
Resource: Zeiss Zen Lite (RRID:SCR_023747)
Curator: @evieth
SciCrunch record: RRID:SCR_023747
Tags
Annotators
URL
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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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RRID:SCR_002285
DOI: 10.1038/s44321-025-00352-x
Resource: Fiji (RRID:SCR_002285)
Curator: @evieth
SciCrunch record: RRID:SCR_002285
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RRID:SCR_023543
DOI: 10.1038/s44321-025-00352-x
Resource: Harmony (RRID:SCR_023543)
Curator: @evieth
SciCrunch record: RRID:SCR_023543
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Addgene #85140
DOI: 10.1038/s44321-025-00352-x
Resource: RRID:Addgene_85140
Curator: @evieth
SciCrunch record: RRID:Addgene_85140
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Addgene #12260
DOI: 10.1038/s44321-025-00352-x
Resource: RRID:Addgene_12260
Curator: @evieth
SciCrunch record: RRID:Addgene_12260
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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
-
RRID: CVCL_2544
DOI: 10.1038/s42003-026-09518-w
Resource: (CLS Cat# 300433/p2464_KHOS-240S, RRID:CVCL_2544)
Curator: @evieth
SciCrunch record: RRID:CVCL_2544
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RRID: CVCL_0439
DOI: 10.1038/s42003-026-09518-w
Resource: (KCLB Cat# 21543, RRID:CVCL_0439)
Curator: @evieth
SciCrunch record: RRID:CVCL_0439
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-
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
-
ATCC CCL-81
DOI: 10.1016/j.xpro.2026.104367
Resource: (IZSLER Cat# BS CL 86, RRID:CVCL_0059)
Curator: @evieth
SciCrunch record: RRID:CVCL_0059
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ATCC CRL-3276
DOI: 10.1016/j.xpro.2026.104367
Resource: (ATCC Cat# CRL-3276, RRID:CVCL_DA06)
Curator: @evieth
SciCrunch record: RRID:CVCL_DA06
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ATCC CRL-4000
DOI: 10.1016/j.xpro.2026.104367
Resource: (ATCC Cat# CRL-4000, RRID:CVCL_4388)
Curator: @evieth
SciCrunch record: RRID:CVCL_4388
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www.sciencedirect.com www.sciencedirect.com
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Jackson LabsCat# 008169
DOI: 10.1016/j.xcrm.2026.102631
Resource: (IMSR Cat# JAX_008169,RRID:IMSR_JAX:008169)
Curator: @areedewitt04
SciCrunch record: RRID:IMSR_JAX:008169
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Jackson LabsCat# 000664
DOI: 10.1016/j.xcrm.2026.102631
Resource: RRID:IMSR_JAX:000664
Curator: @areedewitt04
SciCrunch record: RRID:IMSR_JAX:000664
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RRID:CVCL_0045
DOI: 10.1016/j.xcrm.2026.102631
Resource: (DSMZ Cat# ACC-305, RRID:CVCL_0045)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0045
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www.sciencedirect.com www.sciencedirect.com
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ATCCCRL-3216
DOI: 10.1016/j.str.2026.01.011
Resource: (RRID:CVCL_0063)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0063
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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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RRID:CVCL_6926
DOI: 10.1016/j.redox.2026.104073
Resource: (RRID:CVCL_6926)
Curator: @evieth
SciCrunch record: RRID:CVCL_6926
Tags
Annotators
URL
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www.sciencedirect.com www.sciencedirect.com
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ATCCCRL-11268
DOI: 10.1016/j.neuron.2025.12.028
Resource: (RRID:CVCL_1926)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_1926
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www.sciencedirect.com www.sciencedirect.com
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RRID: IMSR_JAX: 003010
DOI: 10.1016/j.neuron.2025.12.021
Resource: (IMSR Cat# JAX_003010,RRID:IMSR_JAX:003010)
Curator: @areedewitt04
SciCrunch record: RRID:IMSR_JAX:003010
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www.sciencedirect.com www.sciencedirect.com
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RRID: CVCL_1045
DOI: 10.1016/j.neo.2026.101289
Resource: (ECACC Cat# 05092802, RRID:CVCL_1045)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_1045
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www.sciencedirect.com www.sciencedirect.com
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ATCCCat#HTB-38
DOI: 10.1016/j.molcel.2026.01.018
Resource: (RRID:CVCL_0320)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0320
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www.sciencedirect.com www.sciencedirect.com
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ATCCCCL-247
DOI: 10.1016/j.molcel.2026.01.012
Resource: (RRID:CVCL_VU38)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_VU38
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ATCCCCL-121
DOI: 10.1016/j.molcel.2026.01.012
Resource: (BCRJ Cat# 0110, RRID:CVCL_0317)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0317
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ATCCCRL-3216
DOI: 10.1016/j.molcel.2026.01.012
Resource: (RRID:CVCL_0063)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0063
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ATCCCCL-228
DOI: 10.1016/j.molcel.2026.01.012
Resource: (KCB Cat# KCB 200848YJ, RRID:CVCL_0546)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0546
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ATCCCCL-185
DOI: 10.1016/j.molcel.2026.01.012
Resource: (CCLV Cat# CCLV-RIE 1035, RRID:CVCL_0023)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0023
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ATCCCRL-6322
DOI: 10.1016/j.molcel.2026.01.012
Resource: (BCRJ Cat# 0044, RRID:CVCL_0604)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0604
-
AddgenePlasmid #12260
DOI: 10.1016/j.molcel.2026.01.012
Resource: RRID:Addgene_12260
Curator: @areedewitt04
SciCrunch record: RRID:Addgene_12260
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ATCCCCL-243
DOI: 10.1016/j.molcel.2026.01.012
Resource: (KCB Cat# KCB 90029YJ, RRID:CVCL_0004)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0004
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ATCCTIB-152
DOI: 10.1016/j.molcel.2026.01.012
Resource: (NIH-ARP Cat# 177-450, RRID:CVCL_0367)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0367
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ATCCHTB-96
DOI: 10.1016/j.molcel.2026.01.012
Resource: (RRID:CVCL_0042)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0042
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ATCCCCL-2
DOI: 10.1016/j.molcel.2026.01.012
Resource: (TKG Cat# TKG 0331, RRID:CVCL_0030)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0030
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ATCCCCL-221
DOI: 10.1016/j.molcel.2026.01.012
Resource: (RRID:CVCL_0248)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0248
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-
54.241.53.176 54.241.53.176
-
Python
DOI: 10.1016/j.isci.2026.115085
Resource: Python Programming Language (RRID:SCR_008394)
Curator: @areedewitt04
SciCrunch record: RRID:SCR_008394
-
-
54.241.53.176 54.241.53.176
-
Python
DOI: 10.1016/j.isci.2026.115012
Resource: Python Programming Language (RRID:SCR_008394)
Curator: @areedewitt04
SciCrunch record: RRID:SCR_008394
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-
54.241.53.176 54.241.53.176
-
Charles River Strain code: 027
DOI: 10.1016/j.isci.2026.115008
Resource: RRID:IMSR_CRL:027
Curator: @areedewitt04
SciCrunch record: RRID:IMSR_CRL:027
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-
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
-
CRL-1658
DOI: 10.1016/j.isci.2026.114825
Resource: (RCB Cat# RCB2767, RRID:CVCL_0594)
Curator: @evieth
SciCrunch record: RRID:CVCL_0594
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CRL-1446
DOI: 10.1016/j.isci.2026.114825
Resource: (ATCC Cat# CRL-1446, RRID:CVCL_0286)
Curator: @evieth
SciCrunch record: RRID:CVCL_0286
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-
www.sciencedirect.com www.sciencedirect.com
-
RRID: CVCL_0511
DOI: 10.1016/j.intimp.2026.116295
Resource: (ATCC Cat# TIB-71, RRID:CVCL_0493)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0493
-
-
www.sciencedirect.com www.sciencedirect.com
-
ATCCCat# CCL-2
DOI: 10.1016/j.immuni.2025.12.017
Resource: (ICLC Cat# HTL95023, RRID:CVCL_0030)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0030
-
-
www.sciencedirect.com www.sciencedirect.com
-
The Jackson LaboratoryJAX-000664
DOI: 10.1016/j.devcel.2026.01.015
Resource: RRID:IMSR_JAX:000664
Curator: @areedewitt04
SciCrunch record: RRID:IMSR_JAX:000664
-
-
www.sciencedirect.com www.sciencedirect.com
-
ATCCCat# CRL-1682
DOI: 10.1016/j.crmeth.2026.101307
Resource: (NCBI_Iran Cat# C558, RRID:CVCL_0152)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0152
-
ATCCCat# CRL-1469
DOI: 10.1016/j.crmeth.2026.101307
Resource: (ECACC Cat# 87092802, RRID:CVCL_0480)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0480
-
ATCCCat# HTB-26
DOI: 10.1016/j.crmeth.2026.101307
Resource: (RRID:CVCL_0062)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0062
-
ATCCCat# HTB-161
DOI: 10.1016/j.crmeth.2026.101307
Resource: (ATCC Cat# HTB-161, RRID:CVCL_0465)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0465
-
-
www.sciencedirect.com www.sciencedirect.com
-
Jackson Laboratory#000664
DOI: 10.1016/j.cmet.2026.01.019
Resource: (IMSR Cat# JAX_000664,RRID:IMSR_JAX:000664)
Curator: @areedewitt04
SciCrunch record: RRID:IMSR_JAX:000664
-
-
www.sciencedirect.com www.sciencedirect.com
-
ATCCCRL-6475
DOI: 10.1016/j.cmet.2026.01.015
Resource: (KCLB Cat# 80008, RRID:CVCL_0159)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0159
-
ATCCCRL-11268
DOI: 10.1016/j.cmet.2026.01.015
Resource: (RRID:CVCL_1926)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_1926
-
-
www.sciencedirect.com www.sciencedirect.com
-
RRID: CVCL_0007
DOI: 10.1016/j.celrep.2026.117010
Resource: (JCRB Cat# IFO50038, RRID:CVCL_0007)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0007
-
RRID: CVCL_2120
DOI: 10.1016/j.celrep.2026.117010
Resource: (DSMZ Cat# ACC-555, RRID:CVCL_2120)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_2120
-
RRID: CVCL_1609
DOI: 10.1016/j.celrep.2026.117010
Resource: (RRID:CVCL_1609)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_1609
-
Jackson Laboratory#002014
DOI: 10.1016/j.celrep.2026.117010
Resource: (IMSR Cat# JAX_002014,RRID:IMSR_JAX:002014)
Curator: @areedewitt04
SciCrunch record: RRID:IMSR_JAX:002014
-
Jackson Laboratory#000664
DOI: 10.1016/j.celrep.2026.117010
Resource: RRID:IMSR_JAX:000664
Curator: @areedewitt04
SciCrunch record: RRID:IMSR_JAX:000664
-
Addgene # 12371
DOI: 10.1016/j.celrep.2026.117010
Resource: RRID:Addgene_12371
Curator: @areedewitt04
SciCrunch record: RRID:Addgene_12371
-
-
www.sciencedirect.com www.sciencedirect.com
-
KerafastEWL001-FP
DOI: 10.1016/j.celrep.2026.116994
Resource: (RRID:CVCL_ZD32)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_ZD32
-
Jackson Labsstock #000664
DOI: 10.1016/j.celrep.2026.116994
Resource: RRID:IMSR_JAX:000664
Curator: @areedewitt04
SciCrunch record: RRID:IMSR_JAX:000664
-
KerafastEWL002-FP
DOI: 10.1016/j.celrep.2026.116994
Resource: (RRID:CVCL_ZD33)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_ZD33
-
Millipore SigmaSCC193
DOI: 10.1016/j.celrep.2026.116994
Resource: (TKG Cat# TKG 0484, RRID:CVCL_1288)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_1288
-
-
www.sciencedirect.com www.sciencedirect.com
-
AddgeneCat#100097
DOI: 10.1016/j.celrep.2026.116992
Resource: RRID:Addgene_100097
Curator: @areedewitt04
SciCrunch record: RRID:Addgene_100097
-
AddgeneCat#60032
DOI: 10.1016/j.celrep.2026.116992
Resource: RRID:Addgene_60032
Curator: @areedewitt04
SciCrunch record: RRID:Addgene_60032
-
-
www.sciencedirect.com www.sciencedirect.com
-
ZDB-GENO-960809-7
DOI: 10.1016/j.celrep.2026.116971
Resource: RRID:ZFIN_ZDB-GENO-960809-7
Curator: @areedewitt04
SciCrunch record: RRID:ZFIN_ZDB-GENO-960809-7
-
Jackson LaboratoryJIPSC001000
DOI: 10.1016/j.celrep.2026.116971
Resource: (RRID:CVCL_B5P3)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_B5P3
-
ATCCACS-1030
DOI: 10.1016/j.celrep.2026.116971
Resource: None
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0A07
-
ZFIN: ZDB-ALT-050916-14
DOI: 10.1016/j.celrep.2026.116971
Resource: (ZFIN Cat# ZDB-ALT-050916-14,RRID:ZFIN_ZDB-ALT-050916-14)
Curator: @areedewitt04
SciCrunch record: RRID:ZFIN_ZDB-ALT-050916-14
-
ATCCACS-1026
DOI: 10.1016/j.celrep.2026.116971
Resource: (RRID:CVCL_0A05)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0A05
-
ZFIN: ZDB-ALT-060821-4
DOI: 10.1016/j.celrep.2026.116971
Resource: (ZFIN Cat# ZDB-ALT-060821-4,RRID:ZFIN_ZDB-ALT-060821-4)
Curator: @areedewitt04
SciCrunch record: RRID:ZFIN_ZDB-ALT-060821-4
-
ZFIN: ZDB-ALT-120723-3
DOI: 10.1016/j.celrep.2026.116971
Resource: (ZFIN Cat# ZDB-ALT-120723-3,RRID:ZFIN_ZDB-ALT-120723-3)
Curator: @areedewitt04
SciCrunch record: RRID:ZFIN_ZDB-ALT-120723-3
-
ZFIN: ZDB-ALT-110411-1
DOI: 10.1016/j.celrep.2026.116971
Resource: None
Curator: @areedewitt04
SciCrunch record: RRID:ZFIN_ZDB-ALT-110411-1
-
ZFIN: ZDB-ALT-040601-2
DOI: 10.1016/j.celrep.2026.116971
Resource: None
Curator: @areedewitt04
SciCrunch record: RRID:ZFIN_ZDB-ALT-040601-2
-
ZFIN: ZDB-ALT-120828-2
DOI: 10.1016/j.celrep.2026.116971
Resource: None
Curator: @areedewitt04
SciCrunch record: RRID:ZFIN_ZDB-ALT-120828-2
-
-
www.sciencedirect.com www.sciencedirect.com
-
RRID: CVCL_1056
DOI: 10.1016/j.celrep.2026.116968
Resource: (RRID:CVCL_1056)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_1056
-
-
www.sciencedirect.com www.sciencedirect.com
-
ATCCCRL-1619
DOI: 10.1016/j.cell.2026.01.009
Resource: (BCRJ Cat# 0278, RRID:CVCL_0132)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0132
-
ATCCCRL-3216
DOI: 10.1016/j.cell.2026.01.009
Resource: (RRID:CVCL_0063)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0063
-
ATCCCRL-5803
DOI: 10.1016/j.cell.2026.01.009
Resource: (NCI-DTP Cat# NCI-H1299, RRID:CVCL_0060)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0060
-
Addgene; Subach et al.49Cat#55294
DOI: 10.1016/j.cell.2026.01.009
Resource: None
Curator: @areedewitt04
SciCrunch record: RRID:Addgene_55294
-
Charles River088
DOI: 10.1016/j.cell.2026.01.009
Resource: (IMSR Cat# CRL_088,RRID:IMSR_CRL:088)
Curator: @areedewitt04
SciCrunch record: RRID:IMSR_CRL:088
-
ATCCHTB-96
DOI: 10.1016/j.cell.2026.01.009
Resource: (RRID:CVCL_0042)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0042
-
ATCCCCL-185
DOI: 10.1016/j.cell.2026.01.009
Resource: (CCLV Cat# CCLV-RIE 1035, RRID:CVCL_0023)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0023
-
-
www.sciencedirect.com www.sciencedirect.com
-
ATCC) (CRL-3216
DOI: 10.1016/j.celrep.2026.116990
Resource: (RRID:CVCL_0063)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0063
-
-
www.sciencedirect.com www.sciencedirect.com
-
RRID: CVCL_E2RM
DOI: 10.1016/j.cej.2026.174157
Resource: None
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_E2RM
-
-
www.sciencedirect.com www.sciencedirect.com
-
RRID: CVCL_0493
DOI: 10.1016/j.cej.2026.174137
Resource: (ATCC Cat# TIB-71, RRID:CVCL_0493)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0493
-
-
www.sciencedirect.com www.sciencedirect.com
-
RRID: CVCL_0063
DOI: 10.1016/j.canlet.2026.218328
Resource: (RRID:CVCL_0063)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0063
-
RRID: CVCL_1092
DOI: 10.1016/j.canlet.2026.218328
Resource: (NCI-DTP Cat# BT-549, RRID:CVCL_1092)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_1092
-
RRID: CVCL_0062
DOI: 10.1016/j.canlet.2026.218328
Resource: (RRID:CVCL_0062)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0062
-
RRID: CVCL_0553
DOI: 10.1016/j.canlet.2026.218328
Resource: (RRID:CVCL_0553)
Curator: @areedewitt04
SciCrunch record: RRID:CVCL_0553
-
-
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
-
RRID:CVCL_0566
DOI: 10.1007/s00109-026-02650-4
Resource: (BCRJ Cat# 0240, RRID:CVCL_0566)
Curator: @evieth
SciCrunch record: RRID:CVCL_0566
-
RRID:CVCL_2078
DOI: 10.1007/s00109-026-02650-4
Resource: (DSMZ Cat# ACC-541, RRID:CVCL_2078)
Curator: @evieth
SciCrunch record: RRID:CVCL_2078
-
RRID:CVCL_E332
DOI: 10.1007/s00109-026-02650-4
Resource: (RRID:CVCL_E332)
Curator: @evieth
SciCrunch record: RRID:CVCL_E332
-
RRID:CVCL_2989
DOI: 10.1007/s00109-026-02650-4
Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
Curator: @evieth
SciCrunch record: RRID:CVCL_2989
-
RRID:CVCL_J431
DOI: 10.1007/s00109-026-02650-4
Resource: (RRID:CVCL_J431)
Curator: @evieth
SciCrunch record: RRID:CVCL_J431
-
RRID:CVCL_1357
DOI: 10.1007/s00109-026-02650-4
Resource: (DSMZ Cat# ACC-49, RRID:CVCL_1357)
Curator: @evieth
SciCrunch record: RRID:CVCL_1357
-
-
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
-
MMRRC_032108‐UCD
DOI: 10.1002/advs.202513670
Resource: (MMRRC Cat# 032108-UCD,RRID:MMRRC_032108-UCD)
Curator: @AleksanderDrozdz
SciCrunch record: RRID:MMRRC_032108-UCD
-
-
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
-
RRID:SCR_010279
DOI: 10.7554/eLife.108259
Resource: Adobe Illustrator (RRID:SCR_010279)
Curator: @scibot
SciCrunch record: RRID:SCR_010279
-
RRID:SCR_002285
DOI: 10.7554/eLife.108259
Resource: Fiji (RRID:SCR_002285)
Curator: @scibot
SciCrunch record: RRID:SCR_002285
-
RRID:SCR_007370
DOI: 10.7554/eLife.108259
Resource: Imaris (RRID:SCR_007370)
Curator: @scibot
SciCrunch record: RRID:SCR_007370
-
RRID:BDSC_26669
DOI: 10.7554/eLife.108259
Resource: RRID:BDSC_26669
Curator: @scibot
SciCrunch record: RRID:BDSC_26669
-
RRID:SCR_002798
DOI: 10.7554/eLife.108259
Resource: GraphPad Prism (RRID:SCR_002798)
Curator: @scibot
SciCrunch record: RRID:SCR_002798
-
RRID:AB_2335286
DOI: 10.7554/eLife.108259
Resource: (Thermo Fisher Scientific Cat# ICN55976, RRID:AB_2335286)
Curator: @scibot
SciCrunch record: RRID:AB_2335286
-
RRID:BDSC_35785
DOI: 10.7554/eLife.108259
Resource: RRID:BDSC_35785
Curator: @scibot
SciCrunch record: RRID:BDSC_35785
-
RRID:BDSC_32194
DOI: 10.7554/eLife.108259
Resource: RRID:BDSC_32194
Curator: @scibot
SciCrunch record: RRID:BDSC_32194
-
RRID:AB_2307313
DOI: 10.7554/eLife.108259
Resource: (Aves Labs Cat# GFP-1010, RRID:AB_2307313)
Curator: @scibot
SciCrunch record: RRID:AB_2307313
-
RRID:BDSC_36117
DOI: 10.7554/eLife.108259
Resource: RRID:BDSC_36117
Curator: @scibot
SciCrunch record: RRID:BDSC_36117
-
RRID:AB_2687586
DOI: 10.7554/eLife.108259
Resource: (Abcam Cat# ab195173, RRID:AB_2687586)
Curator: @scibot
SciCrunch record: RRID:AB_2687586
-
RRID:BDSC_43963
DOI: 10.7554/eLife.108259
Resource: RRID:BDSC_43963
Curator: @scibot
SciCrunch record: RRID:BDSC_43963
-
RRID:BDSC_5137
DOI: 10.7554/eLife.108259
Resource: RRID:BDSC_5137
Curator: @scibot
SciCrunch record: RRID:BDSC_5137
-
-
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
-
RRID:Addgene_10878
DOI: 10.7554/eLife.108048
Resource: RRID:Addgene_10878
Curator: @scibot
SciCrunch record: RRID:Addgene_10878
-
RRID:CVCL_CW64
DOI: 10.7554/eLife.108048
Resource: None
Curator: @scibot
SciCrunch record: RRID:CVCL_CW64
-
RRID:CVCL_6E02
DOI: 10.7554/eLife.108048
Resource: (RRID:CVCL_6E02)
Curator: @scibot
SciCrunch record: RRID:CVCL_6E02
-
RRID:CVCL_3275
DOI: 10.7554/eLife.108048
Resource: (KCB Cat# KCB 2014059YJ, RRID:CVCL_3275)
Curator: @scibot
SciCrunch record: RRID:CVCL_3275
-
-
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
-
Addgene_169257
DOI: 10.7554/eLife.103784
Resource: None
Curator: @scibot
SciCrunch record: RRID:Addgene_169257
-
RRID:SCR_016434
DOI: 10.7554/eLife.103784
Resource: Suite2P (RRID:SCR_016434)
Curator: @scibot
SciCrunch record: RRID:SCR_016434
-
RRID:IMSR_JAX:012686
DOI: 10.7554/eLife.103784
Resource: None
Curator: @scibot
SciCrunch record: RRID:IMSR_JAX:012686
-
RRID:SCR_003070
DOI: 10.7554/eLife.103784
Resource: ImageJ (RRID:SCR_003070)
Curator: @scibot
SciCrunch record: RRID:SCR_003070
-
RRID:AB_2629482
DOI: 10.7554/eLife.103784
Resource: (Thermo Fisher Scientific Cat# D1306, RRID:AB_2629482)
Curator: @scibot
SciCrunch record: RRID:AB_2629482
-
RRID:CVCL_0063
DOI: 10.7554/eLife.103784
Resource: (RRID:CVCL_0063)
Curator: @scibot
SciCrunch record: RRID:CVCL_0063
-
RRID:SCR_001622
DOI: 10.7554/eLife.103784
Resource: MATLAB (RRID:SCR_001622)
Curator: @scibot
SciCrunch record: RRID:SCR_001622
-
RRID:AB_141611
DOI: 10.7554/eLife.103784
Resource: (Molecular Probes Cat# A-21124, RRID:AB_141611)
Curator: @scibot
SciCrunch record: RRID:AB_141611
-
RRID:AB_2174013
DOI: 10.7554/eLife.103784
Resource: (Millipore Cat# MAB1572, RRID:AB_2174013)
Curator: @scibot
SciCrunch record: RRID:AB_2174013
-
RRID:SCR_011323
DOI: 10.7554/eLife.103784
Resource: pClamp (RRID:SCR_011323)
Curator: @scibot
SciCrunch record: RRID:SCR_011323
-
RRID:AB_2040166
DOI: 10.7554/eLife.103784
Resource: (Alomone Labs Cat# APC-014, RRID:AB_2040166)
Curator: @scibot
SciCrunch record: RRID:AB_2040166
-
RRID:Addgene_135630
DOI: 10.7554/eLife.103784
Resource: RRID:Addgene_135630
Curator: @scibot
SciCrunch record: RRID:Addgene_135630
-
RRID:AB_2576217
DOI: 10.7554/eLife.103784
Resource: (Thermo Fisher Scientific Cat# A-11034, RRID:AB_2576217)
Curator: @scibot
SciCrunch record: RRID:AB_2576217
-
RRID:IMSR_JAX:000664
DOI: 10.7554/eLife.103784
Resource: RRID:IMSR_JAX:000664
Curator: @scibot
SciCrunch record: RRID:IMSR_JAX:000664
-
RRID:IMSR_JAX:003376
DOI: 10.7554/eLife.103784
Resource: (IMSR Cat# JAX_003376,RRID:IMSR_JAX:003376)
Curator: @scibot
SciCrunch record: RRID:IMSR_JAX:003376
-
RRID:IMSR_JAX:027395
DOI: 10.7554/eLife.103784
Resource: (IMSR Cat# JAX_027395,RRID:IMSR_JAX:027395)
Curator: @scibot
SciCrunch record: RRID:IMSR_JAX:027395
-
RRID:Addgene_162375
DOI: 10.7554/eLife.103784
Resource: RRID:Addgene_162375
Curator: @scibot
SciCrunch record: RRID:Addgene_162375
Tags
- RRID:AB_2040166
- RRID:CVCL_0063
- RRID:AB_2174013
- RRID:SCR_011323
- RRID:Addgene_135630
- RRID:SCR_001622
- RRID:IMSR_JAX:000664
- RRID:IMSR_JAX:027395
- RRID:IMSR_JAX:012686
- RRID:IMSR_JAX:003376
- RRID:Addgene_169257
- RRID:Addgene_162375
- RRID:AB_2576217
- RRID:SCR_003070
- RRID:AB_2629482
- RRID:SCR_016434
- RRID:AB_141611
Annotators
URL
-
-
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
-
RRID:SCR_007378
DOI: 10.7554/eLife.101518
Resource: WFU PickAtlas (RRID:SCR_007378)
Curator: @scibot
SciCrunch record: RRID:SCR_007378
-
RRID:SCR_016216
DOI: 10.7554/eLife.101518
Resource: FMRIPREP (RRID:SCR_016216)
Curator: @scibot
SciCrunch record: RRID:SCR_016216
-
RRID:SCR_001622
DOI: 10.7554/eLife.101518
Resource: MATLAB (RRID:SCR_001622)
Curator: @scibot
SciCrunch record: RRID:SCR_001622
-
RRID:SCR_002865
DOI: 10.7554/eLife.101518
Resource: SPSS (RRID:SCR_002865)
Curator: @scibot
SciCrunch record: RRID:SCR_002865
-
-
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
-
RRID:SCR_025474
DOI: 10.14814/phy2.70787
Resource: University of Virginia School of Medicine Exercise Physiology Core Facility (RRID:SCR_025474)
Curator: @scibot
SciCrunch record: RRID:SCR_025474
Tags
Annotators
URL
-
-
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
-
AB_439702
DOI: 10.12688/f1000research.169966.1
Resource: (Sigma-Aldrich Cat# A8592, RRID:AB_439702)
Curator: @scibot
SciCrunch record: RRID:AB_439702
-
AB_141780
DOI: 10.12688/f1000research.169966.1
Resource: (Molecular Probes Cat# A-21424, RRID:AB_141780)
Curator: @scibot
SciCrunch record: RRID:AB_141780
-
AB_3068333
DOI: 10.12688/f1000research.169966.1
Resource: (Proteintech Cat# RGAM001, RRID:AB_3068333)
Curator: @scibot
SciCrunch record: RRID:AB_3068333
-
AB_2535850
DOI: 10.12688/f1000research.169966.1
Resource: (Thermo Fisher Scientific Cat# A-21429, RRID:AB_2535850)
Curator: @scibot
SciCrunch record: RRID:AB_2535850
-
AB_3073505
DOI: 10.12688/f1000research.169966.1
Resource: (Proteintech Cat# RGAR001, RRID:AB_3073505)
Curator: @scibot
SciCrunch record: RRID:AB_3073505
-
AB_439700
DOI: 10.12688/f1000research.169966.1
Resource: (Sigma-Aldrich Cat# A9594, RRID:AB_439700)
Curator: @scibot
SciCrunch record: RRID:AB_439700
-
AB_2723433
DOI: 10.12688/f1000research.169966.1
Resource: (Thermo Fisher Scientific Cat# 711879, RRID:AB_2723433)
Curator: @scibot
SciCrunch record: RRID:AB_2723433
-
AB_2881408
DOI: 10.12688/f1000research.169966.1
Resource: (Proteintech Cat# 60293-1-Ig, RRID:AB_2881408)
Curator: @scibot
SciCrunch record: RRID:AB_2881408
-
AB_2890221
DOI: 10.12688/f1000research.169966.1
Resource: (Abcam Cat# ab213556, RRID:AB_2890221)
Curator: @scibot
SciCrunch record: RRID:AB_2890221
-
AB_3073769
DOI: 10.12688/f1000research.169966.1
Resource: None
Curator: @scibot
SciCrunch record: RRID:AB_3073769
-
CVCL_A6LN
DOI: 10.12688/f1000research.169966.1
Resource: None
Curator: @scibot
SciCrunch record: RRID:CVCL_A6LN
-
AB_3073768
DOI: 10.12688/f1000research.169966.1
Resource: None
Curator: @scibot
SciCrunch record: RRID:AB_3073768
-
CVCL_0042
DOI: 10.12688/f1000research.169966.1
Resource: (RRID:CVCL_0042)
Curator: @scibot
SciCrunch record: RRID:CVCL_0042
-
AB_2890222
DOI: 10.12688/f1000research.169966.1
Resource: Abcam Cat# ab242146, RRID:AB_2890222
Curator: @scibot
SciCrunch record: RRID:AB_2890222
-
AB_2723432
DOI: 10.12688/f1000research.169966.1
Resource: None
Curator: @scibot
SciCrunch record: RRID:AB_2723432
-
RRID:SCR_017655
DOI: 10.12688/f1000research.169966.1
Resource: Cancer Dependency Map Portal (RRID:SCR_017655)
Curator: @scibot
SciCrunch record: RRID:SCR_017655
-
RRID:SCR_017697
DOI: 10.12688/f1000research.169966.1
Resource: McGill University Advanced BioImaging Core Facility (RRID:SCR_017697)
Curator: @scibot
SciCrunch record: RRID:SCR_017697
-
-
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
-
RRID:IMSR_JAX:004682
DOI: 10.1210/endocr/bqaf047
Resource: (IMSR Cat# JAX_004682,RRID:IMSR_JAX:004682)
Curator: @scibot
SciCrunch record: RRID:IMSR_JAX:004682
-
-
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
-
RRID:SCR_022613
DOI: 10.1182/bloodadvances.2025017838
Resource: Fred Hutchinson Cancer Center Flow Cytometry Core Facility (RRID:SCR_022613)
Curator: @scibot
SciCrunch record: RRID:SCR_022613
-
RRID:SCR_022606
DOI: 10.1182/bloodadvances.2025017838
Resource: Fred Hutchinson Cancer Center Genomics and Bioinformatics Core Facility (RRID:SCR_022606)
Curator: @scibot
SciCrunch record: RRID:SCR_022606
-
-
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
-
RRID:CVCL_1171
DOI: 10.1177/03000605261419604
Resource: (BCRJ Cat# 0076, RRID:CVCL_1171)
Curator: @scibot
SciCrunch record: RRID:CVCL_1171
-
RRID:CVCL_1218
DOI: 10.1177/03000605261419604
Resource: (BCRJ Cat# 0301, RRID:CVCL_1218)
Curator: @scibot
SciCrunch record: RRID:CVCL_1218
-
RRID:SCR_012341
DOI: 10.1177/03000605261419604
Resource: Connecticut University Flow Cytometry Core Facility (RRID:SCR_012341)
Curator: @scibot
SciCrunch record: RRID:SCR_012341
-
-
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
-
RRID:SCR_025745
DOI: 10.1128/aem.02407-25
Resource: Max Planck Institute of Biochemistry Mass Spectrometry Core Facility (RRID:SCR_025745)
Curator: @scibot
SciCrunch record: RRID:SCR_025745
Tags
Annotators
URL
-
-
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
-
RRID:AB_2110656
DOI: 10.1126/sciadv.adz2299
Resource: (Millipore Cat# MAB302, RRID:AB_2110656)
Curator: @scibot
SciCrunch record: RRID:AB_2110656
-
RRID:AB_476701
DOI: 10.1126/sciadv.adz2299
Resource: (Sigma-Aldrich Cat# A2547, RRID:AB_476701)
Curator: @scibot
SciCrunch record: RRID:AB_476701
-
RRID:AB_2281020
DOI: 10.1126/sciadv.adz2299
Resource: (Abcam Cat# ab52625, RRID:AB_2281020)
Curator: @scibot
SciCrunch record: RRID:AB_2281020
-
RRID:AB_354737
DOI: 10.1126/sciadv.adz2299
Resource: (R and D Systems Cat# AF1330, RRID:AB_354737)
Curator: @scibot
SciCrunch record: RRID:AB_354737
-
RRID:AB_2089985
DOI: 10.1126/sciadv.adz2299
Resource: (Abcam Cat# ab28146, RRID:AB_2089985)
Curator: @scibot
SciCrunch record: RRID:AB_2089985
-
-
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
-
RRID:CVCL_0038
DOI: 10.1111/febs.70301
Resource: (RRID:CVCL_0038)
Curator: @scibot
SciCrunch record: RRID:CVCL_0038
-
RRID:CVCL_6573
DOI: 10.1111/febs.70301
Resource: (ATCC Cat# CRL-4001, RRID:CVCL_6573)
Curator: @scibot
SciCrunch record: RRID:CVCL_6573
-
-
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
-
RRID:CVCL_0588
DOI: 10.1111/febs.70286
Resource: (RCB Cat# RCB1906, RRID:CVCL_0588)
Curator: @scibot
SciCrunch record: RRID:CVCL_0588
-
RRID:CVCL_0042
DOI: 10.1111/febs.70286
Resource: (RRID:CVCL_0042)
Curator: @scibot
SciCrunch record: RRID:CVCL_0042
-
RRID:CVCL_0594
DOI: 10.1111/febs.70286
Resource: (RCB Cat# RCB2767, RRID:CVCL_0594)
Curator: @scibot
SciCrunch record: RRID:CVCL_0594
-
RRID:CVCL_0030
DOI: 10.1111/febs.70286
Resource: (ICLC Cat# HTL95023, RRID:CVCL_0030)
Curator: @scibot
SciCrunch record: RRID:CVCL_0030
-
RRID:CVCL_0326
DOI: 10.1111/febs.70286
Resource: (KCB Cat# KCB 200942YJ, RRID:CVCL_0326)
Curator: @scibot
SciCrunch record: RRID:CVCL_0326
-
RRID:CVCL_0023
DOI: 10.1111/febs.70286
Resource: (CCLV Cat# CCLV-RIE 1035, RRID:CVCL_0023)
Curator: @scibot
SciCrunch record: RRID:CVCL_0023
-
RRID:CVCL_0291
DOI: 10.1111/febs.70286
Resource: (RRID:CVCL_0291)
Curator: @scibot
SciCrunch record: RRID:CVCL_0291
-
RRID:CVCL_0062
DOI: 10.1111/febs.70286
Resource: (RRID:CVCL_0062)
Curator: @scibot
SciCrunch record: RRID:CVCL_0062
-