490 Matching Annotations
  1. Aug 2020
    1. Free software thus differs from: proprietary software, such as Microsoft Office, Google Docs, Sheets, and Slides or iWork from Apple. Users cannot study, change, and share their source code. freeware, which is a category of proprietary software that does not require payment for basic use.
    1. Co-hyponyms are labelled as such when separate hyponyms share the same hypernym but are not hyponyms of one another, unless they happen to be synonymous
    1. Note that the double quotes around "${arr[@]}" are really important. Without them, the for loop will break up the array by substrings separated by any spaces within the strings instead of by whole string elements within the array. ie: if you had declare -a arr=("element 1" "element 2" "element 3"), then for i in ${arr[@]} would mistakenly iterate 6 times since each string becomes 2 substrings separated by the space in the string, whereas for i in "${arr[@]}" would iterate 3 times, correctly, as desired, maintaining each string as a single unit despite having a space in it.
  2. Jul 2020
    1. The meta charset information must also be the first child of the <head> tag. The reason this tag must be first is to avoid re-interpreting content that was added before the meta charset tag.

      But what if another tag also specified that it had to be the first child "because ..."? Maybe that hasn't happened yet, but it could and then you'd have to decide which one truly was more important to put first? (Hopefully/probably it wouldn't even matter that much.)

  3. Jun 2020
    1. During the fragment hit-to-lead process, we typically synthesize 50–100 compounds to increase the binding affinity from millimolar to nanomolar, and we routinely generate multiple lead series for each target

      50-100 compounds from millimolar to nanomolar, that is too successful, 10^6 increase

    2. the most potent fragment is often not the best starting point for hit-to-lead chemistry.

      a good lession: the most potent hit may not be the best starting point for further optimization.

    3. Although better cross-validation would provide increased confidence in fragment hits, there is a danger that this may also result in the systematic selection of more potent hits,

      this is a dilemma, if you expect a hit to be validated in both NMR and X-ray, you are actually expect a stronger binder.

    4. great importance should be placed on accurately characterizing the solubility of a fragment library

      for X-ray screening, solubility must be good enough. what is the cutoff?

    5. observe a correlation of 30–40% using these two techniques.

      only 30~40% correlation between X-ray and ligand observed NMR

    6. Another area of active debate centres on the lack of correlation of fragment hits obtained using different detection techniques

      I have not notice this before, which reflects my lack of FBDD experiences.

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    1. Computer architecture advancements has led to the rise of multi-core, in-memory DBMSs that employ efficient transaction man-agement mechanisms to maximize parallelism without sacrificingserializability.

      lecture原话

    1. Les droits définis par le décret s’appliquent aux associations de parents représentées au conseil d’école ou au conseil d’administration ainsi qu’à celles représentées au Conseil supérieur de l’éducation, au conseil académique ou au conseil départemental de l’éducation nationale même si elles n’ont pas d’élus dans les instances de l’école ou de l’établissement.

      C'est vraiment un élément important qui différencie des associations locales. Là aussi cela offre une possiblilité supplémentaire à la FCPE vis à vis des parents isolés

  4. May 2020
    1. In a basic configuration, GitLab runs a pipeline each time changes are pushed to a branch. If you want the pipeline to run jobs only when merge requests are created or updated, you can use pipelines for merge requests.
    1. The Microsoft Calculator program uses the former in its standard view and the latter in its scientific and programmer views.
    1. In the context of first-order logic, a distinction is maintained between logical validities, sentences that are true in every model, and tautologies, which are a proper subset of the first-order logical validities. In the context of propositional logic, these two terms coincide.

      A distinction is made between the kind of logic (first-order logic) where this other distinction exists and propositional logic, where the distinction doesn't exist (the two terms coincide in that context).

    1. It may be the case that several sufficient conditions, when taken together, constitute a single necessary condition (i.e., individually sufficient and jointly necessary)
    1. The qualifier of ‘certain circumstances’ is important to highlight here, because it’s often the context in which information exists that determines whether it can identify someone.
    1. However, please note the following: it will depend on how those subdomains are defined. Are they just subsections of a project that belongs together like help.example.com or blog.example.com (and many other possible arrangements that are part of one and the same setup)? In such a case, using the same policy is appropriate. Problems arise when completely different projects which have little to do with one another and whose data collection practices also differ so significantly that they require different privacy policies.
  5. Apr 2020
    1. Now, do I care which one you use? No. As long as you test your code, I am happy. A professional developer should be able to work in either one of these because they essentially do the same thing: test your code.
  6. Mar 2020
    1. A single consent form is useful when consent is requested for a single purpose. Here: analytics

      This seems like an important distinction:  Probably (?) you can only use a simple Agree/Disagree consent request if you only have a single purpose/category that you are obtaining consent for.

      As soon as your site has multiple categories to need consent, then you must allow individual consent/refusal of consent for each individual category/purpose.

      This is alluded to just a little bit further on:

      Consent should also be granular; users must be allowed to selectively decide what types of tracking, analytics and other activities their data can be used for.

    1. However, translating/interpreting is not the only job a polyglot can have. If we speak about a world-language bearer (English, Spanish, Chinese, etc.), the range of possibilities broadens. My uncle has once told me: "You have English, now you can learn anything." The point is, language is a crucial aspect of development both in terms of career and social life. Language(s) is(are) the basis. You move further on learning new knowledge and acquiring new skills with time. Though, they are not limited to the language you know.If you are talented at languages, you can decide which one you are interested in and study it. Once you have decided, you then choose the particular subject field you want to work in. If you are talented "only" at languages, other ways are open to you. You can be a teacher, tutor, again translator/interpreter, etc.All I want to say is language is power. Where I come from, it is a treasure. I do not know what is it like to be a citisen of a large, highly-developed, economically stable, and successful country. Though, I know for sure, if you know and love languages, you will find your place anywhere.
  7. Feb 2020
    1. If something is important but not urgent - like complimenting or encouraging the entire team - use email or post in the channel without @-mentioning the team.
    1. We commit to build the load testing tool with the best developer experience, k6, and developing it in the open with the community, read our document on stewardship of the OSS k6 project. We believe this is key and the necessary foundation to build great developer tooling.
    2. we believe that developer tools should be open source to allow for a community to form and drive the project forward through discussions and contributions. Hence why we built k6, the load testing tool we’ve always wanted ourselves!
    3. We check in our code at the entry point of a pipeline, version control (Git and Github in our case), and then it’s taken through a series of steps aimed at assuring quality and lowering risk of releases. Automation helps us keep these steps out of our way while maintaining control through fast feedback loops (context-switching is our enemy). If any step of the pipeline breaks (or fails) we want to be alerted in our communication channel of choice (in our case Slack), and it needs to happen as quickly as possible while we’re in the right context.
    1. With k6, our goal has always been to create the best load testing tool for the modern working developer and that we do this in collaboration with the k6 community. Our revenue will not come from k6 directly, but from premium value creating offers based on k6. These offers will be made available at https://loadimpact.com. Load Impact premium offers will have focus on providing further simplicity, productivity and ease to use functionality.
    2. We believe the key to Load Impact’s long-term success as a Company is to foster an active community of users around k6 as an open source project. To achieve this long-term goal, it is vital that we do not withhold new features from k6 based on whether or not they compete with our SaaS offering.
  8. Jan 2020
    1. People hate asking sensitive questions. However, it turns out that people don’t hate being asked sensitive questions. So talking around difficult questions in research interviews is a waste of time and money
  9. Dec 2019
    1. Aside from testing, we place high value in documenting code. It's our legacy for anyone who will be working with our codebase in the future. Fortunately, having a component library like Storybook allows us to document components visually and declaratively. Storybook provides a developer with all the information needed to understand the structure and state of a component.
  10. Oct 2019
    1. They have made the mistake of believing that you can optimize life. That if they follow the instructions of some study they will find pure bliss. They will finally escape being human.
    2. You overlook the fact you are capable of figuring things out on your own

      This is something we often forget in the age of Google!

  11. Sep 2019
    1. Mitosis is a method of cell division in which a cell divides and produces identical copies of itself.
    1. systematic domination of women by men

      "systematic domination of women by men" the beside statement is varies according to person to person, that is the right each one but according to my perspective the idea is wrong because after a long period of time each girl will feel some loneliness. This isolation can be avoided if you have some to care you. No women in the could be independent but they can live independently only a certain period after they miss something in their life. Everyone will leave you but the one who love you will stick with your downs and ups. Your parents will pass you but your husband be with you until something has happen. Below you have five important benefits.

  12. Jul 2019
    1. Pair-share: What’s the next counting-by-10 number on the line after 26? Record several student responses on the board.

      This is hard.

  13. Feb 2019
    1. Simply put, your frog is the most important task. It is the thing that moves the needle the most towards your ideal future. It is probably very important, but not very urgent. So our advice (and Brian Tracy’s as well) is to make sure you tackle this MIT at the beginning of your day when you have the most energy and willpower available. Tackling your MIT first thing is extremely important!

      MIT in morning

      max willpower (not decreased cause of decision fatigue during day)

      • max impact on long term goal.. -important but not urgent -procrastinate because (a) big, overwhelm where to start (b) fear of failure - perfection , sense of worth linked
    2. If I were to summarize the book in a single statement, it would be that you should do your most important task (MIT) first thing in the morning.

      eat that frog summary

    1. Compatibility with any process.

      Key point!

    2. Continuous Improvement (Kaizen)It occurred to me rather late that continuous improvement is a risk management strategy.

      Good observation.

    1. people don’t make any difference between planning, estimating and scheduling.

      because they don't understand the differences among these things.

    2. If someone claims that they can effectively schedule the work of a team of knowledge workers more than one week in the future (even this is questionable), slap them in the face and don’t talk to them ever again.
    3. Scheduling work means that we fix the start and end date of each individual task. Scheduling in knowledge work is a waste. Period.

      I couldn't say this more clearly.

  14. Jan 2019
  15. www.at-the-intersection.com www.at-the-intersection.com
    1. o leaving a a longer a trade history on there would be useful is what attracts.
    2. awesome. Maybe like 100 trades back or something because I've run into that same issue on some of the other sites. Even the exchanges themselves, despite being bittrex being such a shitty place to trade, they actually do a good job of leaving, you know, 10 pages of 10 trades each or something on there for you to look. Which is nice because I do find a lot of people or an algorithm will place a really big sell order and an immediate buy right after, at the previous limit. Um, say a sell order for 100 coins and then a one person, one percent of one coin. Or point 01 at the buy order back. So it gets hidden and the candles may show up green. But if you're not looking at the order book, you're going to miss that.
    3. Um, the one thing I did want to see some more of is like under your portfolio, uh, when you're going through the, you know, the rebalancing, the correlation and the optimization, um, would just be some more information about, okay, here's how we did, um, are efficient frontier. Like here's the calculation we used. I know it's one basic calculation, but there are different parameters that people can use in them based on the risk above. So just having more general research on there, just saying, or maybe a link to another page that explains like, here's the calculations that we're using. Here's the portfolio theory, with the correlation index, you know, so setting that up, just showing people some math behind it.
    4. but the order book and the trade history are really important to me.
    5. e benefit. Like I don't have any benefit in blocfolio, like sharing my position size and i know what my position size is, i look at it 10 times a day. I don't see any need for me to put it into blocfolio. I'm mostly concerned with just price data.
    1. virtually every single DevOps success story is based on a multi-year kaizen-based continuous improvement strategy

      multi-year kaizen

    1. Teams pull work when they know they have the capacity for it, rather than having scope pushed on them

      Critical.

    1. Owners are responsible for Privacy overlay assessments of the P/SaaS CSOs used and any applications built on I/PaaS. Specific guidance regarding what Privacy overlay C/CEs apply to CSPs vs Mission Owners will be provided in a future release of this SRG

      Where's the guidance? (We're nearly two years on now.)

    1. Compliance documentation doesn’t tell me what the security posture of a system is now. It’s a point in time analysis that’s useless the moment it’s “saved.”
  16. Dec 2018
    1. Before you implement any data-centric projects, you must know what data you have, where it is located, and how it relates between various systems.
    1. How can you improve both test data preparation and usage? First, you’ll need to develop a strong test data management strategy.
    1. Amazon Macie is a security service that provides customers both visibility and security for the content that they store in Amazon S3.

      Will our data be stored in S3?

  17. Oct 2018
    1. Defenders see it as a harbinger of tolerance and the only ethical and epistemic stance worthy of the open-minded and tolerant. Detractors dismiss it for its alleged incoherence and uncritical intellectual permissiveness.

      The main points for both sides of my paper

    2. Relativism, roughly put, is the view that truth and falsity, right and wrong, standards of reasoning, and procedures of justification are products of differing conventions and frameworks of assessment and that their authority is confined to the context giving rise to them

      Definition, find a twist on this to frame the way I want, at first what seems like a beneficial definition, but one I can reframe and redefine when I need to

  18. Sep 2018
    1. Who are the communicator(s)? What is their interest in the thing being discussed? What's at stake for them; that is, do they have anything to gain or lose? What makes them qualified to speak about it? He is an Ohioan and deserves to to share his opinion just like everyone else.he is comparing the new technology take over to the industrial revolution, and then the pros and cons about it. What is the message of the text? that technology is not as bad as everyone is making it out to be. Who is the audience of the text? all working people that live in ohio What is the exigence for the text? it is teaching everyone about the change and telling them that it is basically fate What is the text's purpose? What does it hope to achieve? What is the text's material means of communication? it is showing us the reality, the future of the working community. this article is basically describing how the work system is going to work out once artificial intelligence is introduced.

  19. Aug 2018
    1. Disengaged, demotivated, disempowered, and disconnected. Isn’t that how employees and customers always are—and always will be?

      脱离,失去动力,失去权力和脱节。是不是员工和客户总是如此 - 而且永远都是如此?

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  20. Feb 2018
    1. Duplicacy does not use file hashes at all to identify previously seen files that may have changed names or locations, but rather concatenates the contents of all files into a long data stream that is cut into chunks according to artificial boundaries based on a hash function.
  21. Dec 2017
  22. Nov 2017
    1. one with a penchant for spending obscene amounts of money to edge out competitors, we can expect the grocery chain to take on an even larger role in everyday Americans’ lives as Amazon begins treating it more like the physical extension of its brand.

      Go to this one

    2. Whole Foods to $3.49 / pound and $2.49 / pound for organic and no-antibiotic varieties, respectively, Prime members will get an additional 50-cent discount.

      Another important thing

  23. Oct 2017
  24. Jul 2017
    1. Visit the submission site at [submission site link]. Note that you cannot save a partially completed submission. If you exit the program before you click on "submit your abstract," your information will be lost and you will need to start over.

      here is the new text:

      Visit the submission site at [test test test].

  25. Mar 2017
    1. corporate entity.

      Is incorporation the final transition to the secular?

    2. The objective of teaching young people is not merely incidental to the work of an order, it is indeed the manner in which the order seeks to achieve its object. For a member of the order, teaching was not merely a job it was a religious vocation. There can no doubt that Brother Cosgrove was in the classroom in Sligo between 1969 and 1972 because he was a member of the Marist Order. That was known, understood and accepted by pupils and parents, and when such individuals looked at the various brothers who staffed the school at any given time, they saw, and were intended to see not just a teacher, but a Marist.

      The past

    3. he relationship between members of an order and his or her fellow members and indeed the order itself was much more intense, constant and all pervasive than the relationship between an employer and an employee, or in the old language of the late Victorian cases, a master and his servant. Everything in the organisation of religious orders is directed towards emphasising the collective. The vow of obedience involves subjugation of individual will to that of the superior. The vow of poverty has the effect of making the member dependent upon the order’s collective resources. The vow of celibacy emphasises the focus of the member on relationships with the order and with God.

      collectivity vs individuality

    4. ndeed, to apply tests drawn from the relatively modern world of commerce and industry to religious organisations which have existed for centuries is in my view, to miss the sheer scale and impact of religious institutions on peoples’ daily lives, particularly in the Ireland of the first three-quarters of the 20th century.

      Modernity vs. religion

    5. here is however in my view something slightly absurd in seeking to draw comparisons between the case of religious orders and businesses. Furthermore, the tests and language applicable when considering the case of employment and analogous relationships, such as “enterprise” and “risk” are not easily applicable in the case of religious orders.

      Risk vs religion?

  26. Feb 2017
  27. Dec 2016
    1. Medication Guide

      Important Links:

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    2. Full Prescribing Information

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    3. Important Safety Information

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  28. Aug 2016
    1. VISITS

      I'm not sure exactly where this would fit in, but some way to reporting total service hours (per week or other time period) would be useful, esp as we start gauging traffic, volume, usage against number of service hours. In our reporting for the Univ of California, we have to report on services hours for all public service points.

      Likewise, it may be helpful to have a standard way to report staffing levels re: coverage of public service points? or in department? or who work on public services?

    1. the response is always, "What is the LGBT community going to do about this?" But the LGBT community doesn't run the schools where queer kids are being bullied, raped, and abused. The LGBT community can't shut down those "houses of worship" where LGBT kids are abused spiritually and their straight peers are given license to abuse them physically. The LGBT community doesn't parent the vast majority of LGBT kids. So the question shouldn't be, "What is the LGBT community going to do about this?", but rather, "What is the straight community going to do about this?"
  29. Jun 2016
    1. The whole city reminded Emma of pictures she had seen of Victorian London: old, brown buildings, a lot of carriages riding around, and a lot of friendly people out and about, chattingin the streets.

      Ik heb hier eigenlijk een heel ander beeld bij. Meer met houten huizen en veel vegetatie (vreemd voor een stad). Anders dan de steden die wij kennen.

    2. Kate asked him why they had flying beds and not mapped the maze with them, and Grandleheart explained that whenever something flew over, a thick cloud would appear and obscure their view.

      Het werkt als een organisme; het veranderd continue. Niet zozeer altijd in beweging, maar anders in bepaalde contexten.

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  30. Jan 2016
  31. Nov 2015
    1. Paul, there is only one thing going on.

      Read from here to the end of the chapter. It is packed with insight and wisdom.

      I don't want to try to tag every concept mentioned.

  32. Aug 2015
    1. the matrix header (containing information such as the size of the matrix, the method used for storing, at which address is the matrix stored, and so on) and a pointer to the matrix containing the pixel values (taking any dimensionality depending on the method chosen for storing) .
  33. Nov 2013
    1. If following a link which goes to an anchor on a page, for example: [2] it doesn't seem to pick up the annotations which are for that page (only annotations made with that exact URL).
  34. Oct 2013
    1. everything that we say is important;

      This is what makes rhetorical strategy so important. Everything said makes an impact, knowing how to peak well is vital to getting across what you want to.