xsltproc est un moteur XSLT en ligne de commande disponible sous MacOS, Linux et Unix, et installable, mais ça a l'air pas immédiat, sous Windows. Sous Unix/Linux/MacOS, en mode ligne de commande, le signe > est un caractère spécial qui indique que le flux de caractères produit par ce qui est à gauche est à écrire dans le fichier dont le nom est à droite.

Is this a quote? If not, the wording is a little unclear

Windows specific function

tmain is a windows only thing, when I tried to understand it from a SO answer my head hurt

that is awful

This can't currently be done using PowerShell Core.

An example to use the cascading submenus on Windows is to add the Desktop toolbar in the taskbar.

https://www.theverge.com/2015/2/23/8089387/microsoft-windows-10-new-icons

I think this link can be a relevant article

The idea of needing a a janitor in space for astronauts is sad and might be true in the near future

Is this an important part to the story? Or just some detail about the room in which us as the reader can picture the room in which the writer is in?

This is great advice, especially the first one. Nothing is said about WWTP, but I think I can easily make the case for turbidity there

What an amazing analogy!

进程间同步使用同一个同步对象的多个句柄

We should probably update this to mention the Windows 10 linux subsystem.

Wow....

Wow! this was a big invention in the arts.

Schrodinger's newspaper delivery boy...

How to zoom out window on macOS

On 2015 Nov 12, University of Kansas School of Nursing Journal Club commented:

Reviewer (Team 2): Jennifer Patton, Jessica Reed, Kendal Miller, Brittanny Nedblake, Christena Beer, Melissa Zanski-Loughlin, & Haydee Fewell (Senior Nursing Students Class of 2016)

Background and Introduction:

        Healthcare is currently going through a major reform due to multiple factors, including a change in government funding and a decline in the economy. As this is reforming, work environments in the health professions are becoming more stressful. Studies have shown that empowered healthcare providers have more of an effect on improving work environments, and effective leadership helps empower the workplace. The purpose of this article was “to test a model linking authentic leadership of manager with nurses’ perceptions of structural empowerment, self-rated performance, and job satisfaction” (Wong & Laschinger, 2012, p. 948). Leadership styles of nurse managers contribute immensely to a healthy work environment and researchers want to test the effectiveness of the authentic leadership style, since it is relatively new. Our team chose this article because we feel that it proved how well authentic leadership could positively affect the nursing work environment and how it can be applied to a wide range of settings.

Methods:

Our group used Google scholar to find research articles related to what we have been discussing in class. We searched the phrase “authentic leadership” and made sure parameters were set to articles that were published in the last five years and found an article that encompassed many of the topics we have discussed in class this year including: authentic leadership, healthy work environments, structural empowerment, and job satisfaction. The study first started out by gathering data from a random sample of 600 registered nurses (excluding manager, charge, or educator positions). They were sent questionnaires that evaluated their current work environments. The Authentic Leadership Questionnaire measured nurses’ perception of how their manager’s leadership style matched up to be an authentic leader. The Conditions of Work Effectiveness Questionnaire II was used to measure their working environment’s empowerment. The Global Job Satisfaction Survey was used to measure job satisfaction, and overall job performance was measured using the General Performance scale (Wong et al., 2012). Due to a 48% response rate, a final sample of 280 participants was utilized for the study. The data received from these surveys was analyzed using SPSS version 19.0 for Windows and the hypothesized model (authentic leadership’s direct affects on structural empowerment which then indirectly impacts job satisfaction and performance) was examined with the AMOS 19.0 version. The target population in this study was registered nurses, because they were the ones that were being affected the most by the leadership styles and empowerment of the nurse manager. The problem of stressful work environments impacts both nurses and patients. Stressful working environments lead to nurses who don’t give as good of care to the patients as they would if they were more content with their job. Restoring a healthier work environment would improve patient safety and better patient health outcomes.

Findings:

        The average age of nurses in the sample used for the research study was 43.4 years and these nurses had about 19 years of experience in the nursing field, working on medical-surgical units or ICU’s. Another important demographic to note is the education level. The majority of nurses represented were diploma prepared. Nurses’ described moderate job satisfaction and performance, which is indicated with a mean of 3.65 and 3.72, and standard deviation of 1.01 and 0.49, respectively. After analyzing the data collected through the different surveys, the researchers found some inconsistencies between the hypothetical model and covariance data that would suggest a direct, instead of indirect, relationship between authentic leadership and nurses’ job satisfaction (Wong et al., 2012). The final model proved to be statistically significant. According to the evidence, “structural empowerment mediated the relationship between authentic leadership and job satisfaction and performance”  (Wong et al., 2012, p. 953). It was also determined that “authentic leadership had a statistically significant positive direct and indirect effect on job satisfaction through empowerment” (Wong et al., 2012, p. 954).  Because this study is one of the first to observe how authentic leadership affects structural empowerment, which in turn impacts nurses’ job satisfaction and performance, further studies of this kind need to be done in order to provide higher external validity and make it transferable to other populations.  Another limitation of this study was that it used self-report measures; so common method variance could potentially be a factor. The authors also note that other studies should be done in order to explore other possible mediators between authentic leadership and job satisfaction and performance (Wong et al., 2012). This study was done in Ontario, Canada, so its important to be aware of the differences between possible studies performed here in the U.S. The demographics in the U.S. may be slightly different, altering the data results. As compared to Canada, nurses working in the U.S. are mainly ADN or BSN prepared nurses.  This education level can impact the degree of job satisfaction and performance as described in the surveys.

Implications:

        This article is one of many that play a key role in nursing practice, because it offers insight on how certain leadership styles can positively influence nursing work environments. When nurse managers empower their employees, they create an atmosphere where nurses are more satisfied and perform their tasks more efficiently. This ultimately increases patient outcomes and leads to higher, quality nursing care. Components of an authentic leader include “transparency, balanced processing, self-awareness, and high ethical standards” (Wong et al., 2012, p. 955). By understanding the qualities that are needed for effective leadership, nurses can further the movement to creating healthy work environments. As future nurses, we believe that this study provides certain criteria that are critical as we begin to search for jobs. We see the value in leadership styles and how that impacts the overall work environment. In addition, according to Kanter’s theory of structural empowerment by having access to opportunity, resources, support and information, nurses feel more autonomous in their jobs and report more meaningful work environments (Laschinger, Gilbert, Smith & Leslie, 2010). All these components are interrelated and strongly impact the microsystem. Our role as healthcare providers is to offer our patients the highest, quality care that results in better patient outcomes. In order to accomplish this, we must establish relationships with our coworkers that are respectful, open and encouraging so that we then feel empowered to practice to the fullest extent of our nursing education. This will transform the nursing profession and the care provided to our patients. 

References

Wong, C.A. & Laschinger H.K.S (2012). Authentic leadership, performance and job satisfaction: the mediating role of empowerment. Journal of Advanced Nursing 69(4). 947-959.

Laschinger, H.K.S., Gilbert, S., Smith, L.M., & Leslie, K. (2010). Towards a comprehensive theory of nurse/patient empowerment: Applying Kanter’s empowerment theory of patient care. Journal of Nursing Management. DOI: 10.1111/j.1365-2834.2009.01046.x

On 2016 Apr 01, Zhiyong Mi commented:

Just downloaded ImageJ from https://imagej.nih.gov/ij/ Image J (bundled with 32-bit Java 1.6.0-24; 44MB )​. Running imageJ on Lenovo 7483 with Windows 7 OS.<br> The glitch is not fixed yet; the black box still shows up. Users should be aware.

On 2015 May 31, Marc Girard commented:

In accordance with my previous criticism regarding the methodological reliability of most studies presented as confirming the safety of vaccines, this investigation raises a number of serious concerns.

Case ascertainment – Whereas the study title makes special emphasis on multiple sclerosis (MS: ICD code 340), case identification includes no less than nine ICD codes, some of which (optic neuritis or acute disseminated encephalomyelitis being sometimes difficult to differentiate from genuine MS, whereas others [transverse myelitis] are generally considered as distinct). The most expected result of such a diagnosis blending is to weaken statistical power and to blur epidemiological evidence.

Vaccination assessment – Only 4.0% of the 3885 controls were exposed to hepatitis B vaccine in the 3 years before the index rate; this may be compared with the study by Hernán MA, 2004 (the design of which was fairly similar), where 2,4% of the 1565 controls were exposed to a recombinant hepatitis B vaccine. The trouble is that this immunization was highly selective in the latter population (UK), whereas it was massive in the former (USA). In spite of this major discrepancy in the vaccine policy between the two countries, the surprisingly small difference between these two percentages raises the hypothesis that, for one reason or another, vaccination recording was incomplete in the American sample. Although duly pointed out as remarkable by Langer-Gould et al., low vaccine exposure in their sample was not seriously discussed by the authors.

Control selection – Although a black ethnicity was the most prominent risk factor identified by the authors in their previous study on the incidence of demyelinating syndromes (quoted as reference 17 in their current paper), one may wonder why their control selection did not include race in their matching method. As it happens, imbalance in the distribution of black race between cases and controls was the most striking feature of the baseline samples characteristics.

Index date – Although the timing of symptoms appearance is generally a crucial argument for causality in drug monitoring (there may be exceptions to this rule), this parameter is never properly considered in investigations devoted to post-vaccine MS. Actually, as the disease may remain clinically silent for years, the relevant parameter is neither the date of diagnosis nor that of the late symptoms which lead to the investigations leading to positive diagnosis. In spite of this, what investigators mean by “symptoms onset date” is never clearly defined: which symptoms? For example, in their abovementioned reference 17 (Table 1), Langer-Gould et al. estimated at 0.9 month the median time from symptom onset to diagnosis, after having stipulated that, defining MS required two or more episodes of MS “separated in time”: is unlikely that 0.9 month is a sufficient time interval to separate two distinct MS episodes… At the opposite side of the clinical spectrum, the very first symptoms of a MS are often an unexplained fatigue, mild paresthesia, etc. the onset of which may be quite close to the time of vaccine injection (a few days or weeks), but which may last for years before onset of more significant symptoms: thus, if one focus on the late significant symptoms, this very long time lag is almost always interpreted as speaking against a vaccine role whereas, when considering the whole of symptoms sequence from its very beginning (i.e. from the time of quite discrete symptoms just after injection), it is on the contrary highly suggestive of a vaccine causality. I have never seen this crucial problem properly taken into account in any database, so that most investigations about the time between vaccination and the onset of MS symptoms are essentially misleading.

Regarding MS and in spite of their denials, the authors ended up to a result very close to that of Hernan et al.’s., namely an overrepresentation of cases (4.2%) as compared to the controls (3.1%) within a time windows of 3 years. Of course, this difference just failed to reach statistical significance but: i) as documented above, the methodological tendency of the authors contributed to decrease the power of their results; ii) amongst the published case/control studies supposed to exclude a post-vaccine risk of MS (by means of like strategies of dilution of the cases or of insufficient observation period), the number of those suggesting (even in a nonsignificant way) an overrepresentation of cases in vaccinated subjects is clearly higher than those suggesting an underrepresentation, and the difference between the two groups of studies is clearly significant from a statistical point of view.

Finally and as with most papers devoted to the safety of hepatitis B vaccines, the authors cannot refrain from concluding that no “change in vaccine policy” is warranted: yet, their investigation is totally devoid of the slightest element likely to validate any vaccine policy, whose potential shortcomings (included issues of cost, of resources allocation, of individual and collective efficacy, of nonneurological risks, etc.) go far beyond the sole issue of MS. In psychoanalysis, such optimism (going far beyond the available evidence from a given investigation) is called “the return of the repressed”…

On 2016 Jan 10, Simon Young commented:

Badawy and Dougherty raise a number of important points in this paper, but there are number of issues that need discussion.

1. The authors suggest that the original 100g amino acid mixture used for acute tryptophan depletion (ATD), which remains the most commonly used mixture in ATD studies, lacks specificity and causes a lowering of dopamine and possibly norepinephrine. The authors say the 100g mixture lacks specificity because the mixture causes a decrease in the plasma [Phe + Tyr]/[CAA] ratio (an index of the transport of the catecholamine precursors into brain) thereby decreasing Tyr availability to the brain. However, they neglect to mention a study that investigated this issue through measurements on cerebrospinal fluid (CSF). Samples of CSF were taken before and after healthy volunteers received the 100g tryptophan-deficient amino acid mixture Carpenter LL, 1998. CSF tyrosine remained unchanged for the first few hours after the amino acid mixture, but rose slightly between about 5 and 10 hours after the mixture. CSF levels of the dopamine metabolite homovanillic acid (HVA) remained unchanged. Why do tyrosine and HVA not decline if the [Phe + Tyr]/[CAA] ratio decreases? Rat brain tyrosine hydroxylase can hydroxylate both phenylalanine and tyrosine, but it is not known whether this is true for the human brain enzyme. However, results from patients with phenylketonuria (PKU), who have very high phenylalanine levels, suggest that the activity of the human brain enzyme towards phenylalanine is not functionally significant. Thus, untreated PKU patients with phenylketonuria have low CSF tyrosine and HVA levels. When patients are treated with a low phenylalanine diet, or with tyrosine, CSF HVA levels increase Lykkelund C, 1988 Lou HC, 1985. Thus, the appropriate ratio to use as an index of tyrosine availability for catecholamine synthesis is [Tyr]/[CAA]. Badawy has stated that [Tyr]/[CAA] declines in a similar way to [Phe + Tyr]/[CAA] after ATD Badawy AA, 2013. However, others have reported that the control and tryptophan-depleted amino acid mixture cause the [Tyr]/[CAA] ratio to decrease slightly Leyton M, 2000, or not at all Golightly KL, 2001. These latter results are consistent with the CSF studies mentioned above. Although the conclusion is not definitive, the results available at this time suggest that the original 100g amino acid mixture does not decrease catecholamine synthesis and there is no convincing evidence it lacks specificity. Thus, there is no need to decrease the CAA in the 100g formula.

2. The authors suggest that the control mixture (the 100g ATD mixture plus 2.3g tryptophan) is inappropriate because it lowers the plasma [Trp/CAA] ratio. A study in which healthy participants were fed diets containing different levels of protein, and their blood was taken during the course of a day, demonstrated that the plasma [Trp/CAA] ratio varies over a two-fold range depending on the protein content of the meals and diurnal variation Fernstrom JD, 1979. The original ATD control mixture is based on the amino acid profile in human milk, so its effects would not be unphysiological to any important extent Young SN, 2013. There is a big separation between the effect of the control and depleting amino acid mixtures, as the level of CSF tryptophan after the depletion mixture is only 16.3% of the level after the control mixture Moreno FA, 2010. Some studies have used a 25g ATD mixture as a control for the 100g ATD mixture and no mood changes were seen after the control treatment e.g. Booij L, 2005. Thus, using a control mixture that causes a small decline in the [Trp/CAA] ratio does not seem to be a problem and, being a conservative control, may decrease the chance of a type I error.

3. The paper suggests various criteria for the ideal amino acid depletion and loading formulations. One of these is “Robust and reproducible changes in the study parameters”. Presumably the “study parameters” refer to biochemical changes rather than changes in mood, cognition or other outcomes. The main parameters the paper refers to are changes in plasma levels of amino acids, and in particular ratios such as [Trp/CAA]. The [Trp/CAA] is a rough index of the uptake of Trp into brain, which will be rough index of the brain tryptophan level, which is only one of several factors that regulates brain serotonin synthesis. A more valid method to obtain information is to look at measures related more directly to brain tryptophan levels and brain serotonin synthesis. An index of these can be obtained by the measurement of tryptophan and 5-HIAA in CSF. The original 100g ATD mixture has been shown to decrease human brain tryptophan and serotonin synthesis in 5 studies using measurements on CSF Carpenter LL, 1998, Moreno FA, 2000, Moreno FA, 2010, Salomon RM, 2003, Williams WA, 1999, and to decrease human brain serotonin synthesis in one study using a positron emission tomography method Nishizawa S, 1997. Currently no other method for ATD has been validated in this way. Another criterion is “Freedom from, or acceptable (tolerable), side effects not leading to attrition”. In discussing this issue the authors fail to mention two important issues. First, serotonin receptors in the gut and brain are involved in nausea and emesis Hasler WL, 1999. Second, bright light, relative to dim light, decreases side effects after ATD aan het Rot M, 2008. This suggests that central changes may be partly responsible for nausea, and that a greater lowering of serotonin, which may be more likely to reveal effects of ATD on mood, behavior or cognition, may also be more likely to induce nausea. Furthermore, there is currently no direct comparison of the 100g mixture with any alternative mixture, so direct evidence that the 100g mixture causes greater side effects is lacking.

4. Standardizing the amino acid formulation for ATD is only one factor that will help to increase the comparability of research reported in different studies. Some important factors have not always been controlled, while others cannot be controlled across studies. For example, the expectations that participants will have, that might influence their responses, could be influenced by the wording of the consent form and the demeanor and empathy of the person interacting with the participants. Other factors can be controlled. For example, bright light can reverse mood effects of ATD aan het Rot M, 2008 so studies should not be carried out in rooms with windows that can let in sunlight, and the light level should be standardized at a particular level. I suggest 200-300 lux. Between taking the amino acid mixture and being tested there is a period of several hours. If the participants are allowed to interact with others during this period this may influence their mood. For most people agreeable interactions are associated with better mood and quarrelsome interactions are associated with worse mood Côté S, 1998. Therefore interactions between research participants and research staff should be minimized. This can be done by keeping research participants by themselves in a room, and minimizing their interactions with research staff, while giving them access to relatively affectively neutral reading material and movies to avoid boredom between giving them the amino acid mixtures and testing. This has been done in my laboratory, e.g. Benkelfat C, 1994, and I suggest that this should also be standard practice in ATD studies.

In conclusion, the original ATD mixture is the only mixture that has been shown to lower serotonin synthesis in human brain, and criticisms of the method are not well supported. Currently it remains the best candidate for a standard mixture to use in ATD studies, although future studies may change this conclusion.

On 2015 Sep 20, Xinan Holly Yang commented:

Thank you for pointing out. We have fixed the bug in the seq2pathway version >=1.1.6 as described below:

1) The new seq2pathway package runs on both Windows and Linux-like systems.

2) We activated a demon code:

data(ChipseqPeakdemo)

runseq2gene(inputfile=ChipseqPeakdemo)

3) We replaced the absolute path with Sys.which("python").

The significance of the package for the end-users could be:

1) It provides a detailed map and a flexible search of the human and mouse genome. Compared to other tools using the UCSC genome, we processed the newest GENCODE data thus can provide more information for the non-coding regions. Importantly, the runseq2gene() function is designed to find more target gene candidates for a given genomic locus using a customized search radius, which will help users to study trans-regulation. In fact, we have applied the method for the biological knowledge discovery (PLoS Genet. 2014 Oct; 10(10): e1004604, PLoS Genet. 2014 Oct; 10(10): e1004604.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214600/).

2) The se2pathway package implements a unique gene2pathway algorithm termed FAIME (PLoS Comput Biol. 2014 May;10(5):e1003609. http://www.ncbi.nlm.nih.gov/pubmed/22291585) and other three widely-used gene-set analysis (GSA) approaches. It also provides a way to include user-defined gene-sets, which is an adding to the current GSA tools and is important for the discovery of function. Unlike conventional GSA approaches, the package also calculates a corrected background for a more accurate Fisher's exact test (We have introduced the algorithm at BMC Medical Genomics 2015, 8(Suppl 2):S6 http://www.biomedcentral.com/1755-8794/8/S2/S6).

3) Furthermore, the package provides end-users a one-command option to find enriched pathways from 'omic' data.

Looking forwards to more users and comments and we will further improve the package.

-Holly

On 2017 Apr 25, Paul Grossman commented:

Quintana et al. (2016) suggest that individual difference in respiration rate is only correlated with high-frequency heart-rate variability (HF-HRV), i.e. respiratory sinus arrhythmia (RSA) among seriously mentally ill people, but not among healthy individuals. The data presented has several methodological problems that seem very likely to severely compromise the authors' conclusions:

1. The authors report respiration frequency as the peak frequency in a band range between 0.15-0.40 Hz. Resting respiration rate (i.e. frequency), however, is rarely a constant phenomenon for most people within a resting period of several minutes: some breaths are longer, some are shorter, and the peak frequency does not necessarily reflect average breathing rate; in fact, there are very likely to be different peaks, and only the highest peak would have been used to estimate (or misestimate) average respiratory frequency. Spectral frequency analysis, therefore, is a highly imprecise method to calculate mean breathing frequency (perhaps, the difference in relations found between mentally ill vs. healthy people were merely due to increased variability of respiratory frequency among the ill individuals; see Fig. 1F). In any case, this may be be sufficient to disqualify the main conclusions of the study.

2. However, there is may be even a more serious problem that invalidates the conclusions of this investigation. As already mentioned, the authors examined respiration frequencies only between 0.15-0.40 Hz; this corresponds to a range between 9 and 24 breaths/minute. Already in 1992, we demonstrated among a group of healthy participants that a sizable proportion of participants manifest substantial proportions of resting breathing cycles below 9 cycles per minute: among 16 healthy individuals carefully assessed for respiration rate during a 10-minute resting period, we found that half of the participants showed 1/5 of their total breathing cycles to be slower than 9 cycles/minute (cpm); over 60% of participants showed >10% of their cycles to be slower than 9 cpm (also very likely thqat a substantial proportion of breaths occurred beyond 24 cpm). Thus, accurate estimation of mean resting respiration frequency is also seriously compromised by the insufficient range of frequencies included in the analysis. See Grossman (1992, Fig. 5): Grossman, P. Biological Psychology 34 (1992) 131 -161

https://www.researchgate.net/profile/Paul_Grossman2/publication/21689110_Respiratory_and_cardiac_rhythms_as_windows_to_central_and_autonomic_biobehavioral_regulation_Selection_of_window_frames_keeping_the_panes_clean_and_viewing_the_neural_topography/links/5731a22708ae6cca19a2d221/Respiratory-and-cardiac-rhythms-as-windows-to-central-and-autonomic-biobehavioral-regulation-Selection-of-window-frames-keeping-the-panes-clean-and-viewing-the-neural-topography.pdf?origin=publication_detail&ev=pub_int_prw_xdl&msrp=vu97U8y7CNd-ip3iK-qeQgkeqfmS6EwOYfT0BMazIWb4K9Weys1ta4uRS9rdGDRYEbtODvNOG_dr7MWpJIsjJrRkt_z8sTfSS4XmxvaEPMo.DabVyZLtsNb0XPkl_aRXgRYPgmzZVGFb4rchSD_o4vKn98sRTVYBXvo7RQOTYFxDbL7VMx9qNlfuFZvJNy8-9g.kd_GECHVk8wJ18QwWTmSdS3htJncx0qJ0Okn_km-wIHEkyXmPXbXIO-Rb_KUvz_72b5WrLKh7otlmZ6awszetQ.c3eR_WnqJ55XOex_Q4-EHpow-8RGg-Oi87AAPSljLLDtjYimkEgJ99Lu9lmclW4kkI11Jzzp2mkQ4pKenDt6BA

It is also unfortunate that the authors merely cited a single investigation that unusually showed no relation between individual differences in respiration frequency and RSA magnitude (i.e. Denver et al., 2007), but none of the many studies that have found correlations in the range of r's= 0.3-0.5; e.g. https://www.researchgate.net/publication/279615441_Respiratory_Sinus_Arrhythmia_and_Parasympathetic_Cardiac_Control_Some_Basic_Issues_Concerning_Quantification_Applications_and_Implications

http://journal.frontiersin.org/article/10.3389/fphys.2016.00356/Fülle

https://pdfs.semanticscholar.org/6e44/e75dd2061a43cc69a4354171540e8a98e6a5.pdf

The Denver et al. study, additionally, used the same methods inaccurately to calculate respiration rate.

Paul Grossman Pgrossman0@gmail.com

On 2017 Jan 03, Daniel Schwartz commented:

The BC Cardiac Surgical Intensive Care Score is available online or via the Calculate mobile app for iOS, Android and Windows 10 at https://www.qxmd.com/calculate/calculator_36/bc-cardiac-surgical-intensive-care-score

Conflict of interest: Medical Director, QxMD

On 2017 Jun 29, Antoine Depaulis commented:

This study presents interesting behavioral observations during seizures in absence epilepsy (AE). However, there are many overstatements that could be misinterpreted. This begins with the flawed premise that anything less than full loss of consciousness during spike-wave discharges (SWD) is not AE. The broad group of experts in absence epilepsy who signed this response strongly disagree as outlined below. A more complete collective response can be found at: <https://dl.dropboxusercontent.com/u/3541791/Collective reply to Taylor et al_2017.pdf>

1. Partial consciousness during SWD The authors claim that patients with AE experience "profound loss of consciousness" during seizures. On the contrary, some preservation of consciousness is quite common in human AE. Many clinical studies have shown highly variable responsiveness depending both on task difficulty and vigilance level, even from one SWD to the next in the same individual (Blumenfeld, 2005, Guo et al., 2016). Perception of sensory stimuli, discrimination between relevant and irrelevant stimuli during absence seizures and preservation of some cortical processing has been shown in both rat models and human patients (e.g., Inoue et al, 1992, Chipaux et al., 2013, Berman et al., 2010, Drinkenburg et al., 2003, Guo et al., 2016). In addition, as the authors acknowledge, external stimuli like those in this study can increase vigilance and reduce SWD. Therefore, preserved ability to respond during a task or to modulate seizure severity is not a surprise; instead it provides further support for face validity of rodent SWD for human absence seizures.

2. SWD occur in several rodent strains The occurrence of SWD in some animals from outbred rodent strains has been published many times since the 60’s (Marescaux et al., 1992). However, SWDs are not observed in many individual animals in most inbred or outbred rodent strains (e.g., Letts et al., 2014). For example, when rats with SWD (about 30%) were selected from the initial Wistar colony of Strasbourg to produce the GAERS substrain, about 70 % of the colony did not have SWD and were bred as the non-epileptic control (NEC) strain. No NEC display SWD, even when over one year old (Depaulis et al., 2016). Why SWD are so prevalent in some outbred strains is unknown but might be due to preferential selection of dominantly inherited mutated AE genes in docile animals chosen for breeding. The many examples of single gene mutations in mice that lead to SWD/AE not seen in wild type littermates (Maheshwari and Noebels, 2014), provide further evidence that SWD are not normal in rodents. Some monogenic mutations likely result from genetic drift, such as the spontaneous Gria4 gene mutation causing SWD in C3H/HeJ mice, modulated by SWD suppressor mutations in other genes (Beyer et al., 2008, Frankel et al., 2014). Several additional differences between rodents with or without SWD make it very doubtful that SWD reflect “typical rodent behavior” (see PubMed commons for further details).

3. SWD/immobility as a model of absence epilepsy The authors disregard 4 decades of work firmly demonstrating the face validity, pharmacological predictivity and construct validity of rats and mice with SWD as models for AE (see Jarre et al., 2017 for a recent review).These animals fulfill many features relevant to the human AE (Guillemain et al., 2012). In addition to SWD, immobility and mild facial clonus, rodents models exhibit behavioral, structural, molecular and functional co-morbidities not seen in animals without SWD, but also observed in human patients (Shaw, 2007). Furthermore, the anti-epileptic drug profile in rodent AE models corresponds remarkably well with effects in human patients (Depaulis and van Luijtelaar, 2005, Shaw, 2007, Jarre et al., 2017). Over 20 single gene mutations associated with SWD, have been identified in mice and in rats that are consistent with findings in human AE (Powell et al., 2009, Noebels and Sidman, 1979) (Maheshwari and Noebels, 2014). Finally, many electrophysiological (see Depaulis et al., 2017 for a recent review), and fMRI studies (David et al., 2008, Mishra et al., 2011, 2013) in rat AE models agree with clinical data (Westmijse et al., 2009, Hamandi et al., 2008).

Based on these lines of evidence, we assert that SWD/immobility represents a form of epilepsy in rodents. In our view, these episodes are not a natural behavior nor do all individuals display this trait. Studying SWD, in both outbred and inbred strains as well as single gene mutations, has already enabled 1) the development of predictive models of the efficacy of antiepileptic drug efficacy (Tringham et al., 2012, Marks et al., 2016, Glauser et al., 2017), and 2) enhanced understanding of the pathophysiology of cortico-thalamic circuitry that generates and maintains SWD and the mechanisms underlying associated comorbidities.

Contributors and institutions (by alphabetical order) Hal Blumenfeld, Yale University, New Haven, CT, USA Stéphane Charpier, Pierre and Marie Curie University and INSERM, France Doug Coulter, University of Pennsylvania, Philadelphia, USA Vincenzo Crunelli, Cardiff University, Cardiff, UK. Antoine Depaulis, Grenoble Alpes University and INSERM, France Wayne Frankel, Columbia University, NY, USA Martin J. Gallagher, Vanderbilt University, Nashville, TN, USA John Huguenard, Stanford University, Stanford, CA, USA Cian McCafferty, Yale University, New Haven, CT, USA Richard Ngomba, University of Lincoln, UK Jeffrey Noebels, Baylor College of Medicine, TX, USA Jeanne T. Paz, Univ California & Gladstone Institute of Neurological Disease, San Francisco, USA Terence J. O’Brien, University of Melbourne, Melbourne, Australia Filiz Onat, Marmara University, Turkey Gilles van Luijtelaar, Donders Centre for Cognition, Radboud University, Nijmegen, the Netherlands Laurent Vercueil, Grenoble University Hospital, Neurology Department, Grenoble, France

REFERENCES Berman R et al. (2010) Epilepsia 51:2011–2022. Beyer B et al. (2008) Human Molecular Genetics 17:1738–1749. Blumenfeld H (2005) Epilepsia 46 Suppl 9:21–33. Chipaux M et al. (2013) PLoS One 8:e58180. David O et al. (2008) Plos Biol 6:e315–e2697. Depaulis A, Charpier S (2017) Neurosci Letters 17:30141-6. Depaulis A et al. (2016) J Neurosci Meth 260:159–174. Depaulis A, van Luijtelaar G (2005) In: Models of seizures and epilepsy (Pitkänen A, Schwartzkroin P, Moshe S, eds), pp 233–248. Amsterdam: Oxford: Elsevier Academic. Drinkenburg WHIM et al. (2003) Behavioural Brain Research 143:141–146. Frankel WN et al. (2014) PLoS Genet 10:e1004454. Glauser TA et al. (2017) Ann Neurol 81:444–453. Guillemain I et al. (2012) Epileptic Disord 14:217–225. Guo JN et al. (2016) The Lancet 15:1336-1345 Hamandi K et al. (2008) NeuroImage 39:608–618. Inoue M et al. (1992) Electroencephalogr Clin Neurophysiol. 84:172-9. Jarre G et al. (2017) In: Models of seizure and epilepsy. Second edition (Pitkänen A, Buckmaster P, Galanopoulou AS, Moshe SM, eds). Elsevier, in press. Letts VA et al. (2014) Genes, Brain and Behavior 13:519–526. Maheshwari A, Noebels JL (2014) Monogenic models of absence epilepsy: windows into the complex balance between inhibition and excitation in thalamocortical microcircuits, 1st ed. Elsevier B.V. Marescaux C et al. (1992) J Neural Trans - S35:37–69. Marks WN et al. (2016) Eur J Neurosci 43:25–40. Mishra AM et al. (2013) Epilepsia 54:1214–1222. Mishra AM et al. (2011) J Neurosci 31:15053–15064. Noebels JL, Sidman RL (1979) Science 204:1334–1336. Powell KL et al. (2009) J Neurosci 29:371–380. Shaw FZ (2007) 7-12 Hz J Neurophysiol 97:238–247. Tringham E et al. (2012) Science Transl Med 4:121ra19–121ra19. Westmijse I et al. (2009) Epilepsia 50:2538–2548.

an MP3 player? The illustration makes me think of steampunk literature (futuristic technology in the past)

Why did writer include this detail?

The fact that the bed is nailed down, that the windows are barred, and that there are scratches on the wall and floor makes me feel like this room once housed someone against their will. Maybe another "patient" like the main character

This slippery slope argument that John makes for not changing the wallpaper is reminiscent of the attitude of people in power.

Those who have control do not want to see change and thus resist it as much as possible. The argument that if one small thing changes, then people will want more and bigger changes.

Change, to the ruling class, is perhaps equivalent to relinquishing control; the more things change and the more dramatic the change, the more power they lose. John wants to remain dominant over his wife and therefore refuses to comply to her requests.

This seems to be a moment of mania. Has the narrator gone mad? What has happened to where she needs to react this way, it being the final day before she goes home?

The fact that her husband put her in a room with barred windows, a room that was for children, just says that this man is treating his wife as if she was a child and not equal to him, mental illness aside. She tells him she wants the room downstairs with the flowers and she gets shut down for almost everything she asks him. This leads to the obsession with the yellow wallpaper and it's interesting that she ends up seeing bars in the wallpaper and then a woman behind those bars. It's like a reflection of herself, a way to force her to see what her reality is beneath the appearance, what Adams argued in regards to his own male life and existential drama.

She is not seeing this woman in the wallpaper, but instead she is seeing her own reflection.

Only underlining the fact that this room is a prison which points to the idea of two-ness. The room is where she resides but it is also where she is withheld. The bars represent a veil of sorts

In digital works when audience participation is required, what is the role of the audience member? Here, we see that the audience's bodies are used as images for this piece, as well as determining the behavior of the text in this piece. In this way, are they partly author as well?

the decorations seem very puritan/spartan

This doesn't seem to work with Windows 10.

This response particularly confuses me, because I along with some of my younger nieces and nephews experienced cars with manual windows. I feel like a lot of times older people just assume that they know what younger people do and don't remember and what they did and didn't experience.

She is asking the reader to focus on her book and not be distracted by anyone else.

While I do see how some of the depicted figures in the stained glass window could cause controversy, I think it would be wrong for them to amend the windows because they show America's history and they tell the story of a time that will be encased in history because of that glass.

The stained glass windows not only showed the tramendous amount of money and craftsmanship put into the castle, but also depicted scenes from the old south to show what happened during the race riots.

Woolf is giving quite a meandering narrative that feels confusing, but also flows in a peculiar way. However, what is the significance of the wandering parts that feel unimportant?

The brain's limit at multitasking

windows event viewer and even tracing for windows are different

Irwin Consulting Services Review - How to deal with holiday decorations safely

It is already the month of December and to those individuals having a weak heart saying it is too late to put holiday decorations at their home, don’t be. Filling your home with pretty and lovely decorations would not take a very long time so gear up and begin beautifying your house right now. Knowing that you’ll apply your personal style and preferences in designing your house will give you an exciting feeling, but together with that sentiment, you need to be very careful in designing especially when it comes to electric materials.

Some don’t have to feel lonely walking at night in their neighborhood because a lot of houses were so bright and even sparkles the night with their decorative lights and other holiday-themed decorations. Irwin Consulting Services agrees that the holiday season can indeed spread love and joy all around the world.

However, the holiday season also calls for a cold weather, which is an unavoidable circumstance leading to every household use a lot of heat sources. You need to be careful in decorating your home since many heat sources are around. You will also have to deal with some electrical connections when putting your holiday decorations like the Christmas lights into place. Double check the extension cords or power strips along with all the wirings if each is safe to use and has no damage at all. Learn how much current is running through the cords and determine if those were the proper and right numbers. Keep the Christmas tree at least 3 feet away from heat sources such as space heaters and fireplaces.

Irwin Consulting Services would like you to choose properly on what kind of Christmas tree you’re going to put in your house. You can settle with a real or live tree or an artificial one, but most importantly, remember to avoid very dry trees because they are weak to fires. Before placing a live tree on its stand, make sure to cut 1-2 inches from the base of the trunk to ensure good water absorption when filling it with water.

Outdoor decorating should be done with proper caution. Each equipment and decoration you’re going to use must be labeled for outdoor use. Follow the careful guidelines provided especially on electrical products. The amperage rating of the extension cords should match the power needs of the electrical items (amperage). Your electric lights and decorations should be plugged into circuits protected by ground fault circuit interrupters or GFCIs. Maintain distance from power lines while doing outdoor decorating as well. Keep electrical outlets organized to prevent overloading. Do not plug a lot of electrical decorations or devices all at once. You must not let overheating to happen and start a fire.

Confirm if there’s also a proper insulation on electrical cords by checking if they were not pinched in windows, doors or under heavy objects. Be careful about installing the decorative lights as well to ensure that there would be no damage to its cord’s insulation. Unplug electrical decorations when replacing bulbs or fuses. In addition, turning off all indoor and outdoor electrical decorations must be practiced before going to bed or leaving the house.

Candles with a good scent can indeed illuminate the night of the holiday season, but these real candles must not be left unattended for a long period of time to avoid fire accidents. Keep them in a spot that is also safe from the reach of little children and was away from combustible objects. Put out its fire if ever you’re going to sleep or going outside your home for a long time.

Irwin Consulting Services promises to remain committed to helping companies, professionals, or individuals in maintaining public safety and would also like to encourage each household to do the same and be dedicated to their own safety this holiday season.

Irwin Consulting Services Review - Keep your home and family safe against wildfires with these tips

The wildfires reported this year conclude some of the biggest wildfires happened in different areas such as in Los Angeles, British Columbia, and Montana. Wildfires can leave a lot of destroyed homes and properties and even fatalities fast. Its furious flames can spread out on a large scale, making it difficult for firefighters and local authorities to get rid of it. It is often terrifying to witness a huge natural calamity taking place within your area and its results were indeed distressing to see. A wildfire and the path that it is going to take can’t be accurately predicted, which calls for utmost preparation to every household to avoid such grave danger.

But despite this, local authorities and various organizations from many places around the globe are committed to keeping the public safe from the threats of natural calamities. Irwin Consulting Services also belong to those who work hard for the public safety. This post was specifically prepared by them to help every household in keeping their home safe from wildfires.

Make adjustments to your roofs

Think about having rated “A” fire-resistant roofs to further protect your home. Roofs are undeniably the weak-spot of a house when it comes to fires so you must begin making better adjustments on it first. You must also clean the roof on a regular basis to avoid a lot of dead leaves piling up the place and being a fuel to fires.

Create changes to your windows

To better protect your home, your windows should be upgraded to become stronger against fires as well. Choose heat-resistant materials in doing upgrades to your windows. A wildfire that is not yet reaching your home can already show its effects through its extreme heat. That heat can enter the windows and create a fire on drapes and nearby furniture already. Irwin Consulting Services would like you to have fire-rated glasses on your windows and non-combustible shutters too.

Settle on a good location

Choose a convenient location to spend the rest of your lives with your family. Make sure that it is a safe neighborhood and is not prone to frequent fires. You are advised to conduct a thorough research to determine the best location for your family.

Put some modifications on the site layout

Ensure at least 30 meters of distance and incombustible material between the green lands and your home by having wider driveways, patios and low-growing fire-retardant plants. This way, you’re also helping firefighters in bringing their heavy and big equipment near your house in case of fire emergencies.

Maintain a clean surrounding around the green areas

Gather dead and decaying wood and put them away because such can fuel a fire. Get rid of fallen and dead branches too. Think about cutting the branches that were too close to your roof or overhangs it. Make cleaning around the green areas around your home a habit.

Be wary of embers

Eaves and vents openings were the most susceptible parts to flying embers. Once the embers entered through those parts, it could start a fire inside your home. In order to better protect your house, screen those openings and make sure they were properly maintained. Do not forget about cleaning the gutters as well.

Protect your home and your family to the best of your ability and always be prepared for immediate dangers of natural calamities. Trust organizations such as Irwin Consulting Group in helping local authorities in making sure of a safe neighborhood. But aside from their expertise, self-preparation and readiness could save and protect your entire family as well.

Interesting way to put it.

A des connaissances en LISP

Irwin Consulting Services Review - Tips to protect your home from a wildfire

This year, cases of huge wildfires occurred on multiple continents have made the whole world worried and sad because of such devastating calamity that result in a lot of damaged properties and homes, and even lost lives. Wildfires can cause a tragedy fast and this chaotic phenomenon often gives firefighters and local authorities a hard time extinguishing its raging fires. Natural calamities are frightening and their effects on lands and human lives can be heartbreaking. Wildfires can start any time without any warnings and the path that it is going to take is usually hard to predict.

Different companies and organizations around the world have been working hard to protect the public from immediate dangers of natural calamities, and one of them is Irwin Consulting Services. And one of their objectives is to protect households from wildfires and this post aims to help you in keeping your home safe against such a natural threat.

Tip #1: Upgrade your roofs

Consider about installing ignition resistant roofs since roofs were often the most vulnerable part of the house to fires. Protect your home and your family from the quick fires by having fire-resistant roofs. The most effective and resistant roofs were given the rate of “A” so choose roofs with such label. Maintain a clean roof as well to prevent having piled up dead leaves and become fuel to fires.

Tip #2: Put double protection on windows

In order to provide more protection to your house, upgrade your windows and drapes too. Use heat-resistant materials in improving your windows to become fire-resistant. The drastic heat coming from a distant wildfire can already affect your house by going right through the windows and put drapes and furniture on fire. Further protection to your house can begin with installing fire-rated glasses on your windows and investing on non-combustible shutters.

Tip #3: Choose the most convenient location

Learn about the location of where you are going to buy or build a house. Determine if the neighborhood had a lot of incident of fires in the recent years. Make sure of a place that will not threaten the safety of your home and your family. Irwin Consulting Services encourages you to do a careful research regarding this subject.

Tip #4: Put adjustments on the site layout

Make wider driveways, patios and even put low-growing fire-retardant plants to have at least 30 meters of distance and incombustible material between the wild lands and your home. Wider driveways and turn-around is also for the convenience of firefighters in bringing their huge and heavy equipment close to your home in the event of emergencies.

Tip #5: Keep your green surroundings clean

Clean the dead and decaying wood around your home because such can also be the reason to start a fire in your area. Do not forget about fallen and dead branches as well. Branches close to your roof or overhangs it should be cut. Maintain a clean setting around your house especially in spots that have a lot of trees.

Tip #6: Watch out for embers

Never ignore the danger that flying embers could bring to your house. The openings of eaves and vents are the most vulnerable parts of the house to embers because it can fly into them and can begin a fire inside. Keep those openings screened and properly maintained to avoid tragedies inside your shelter. Gutters should also be cleaned for added protection.

Irwin Consulting Services would like each household to aim for a better protection at their homes and be prepared for any natural calamities to avoid regrets. Be safe always.

Maddy has never been outside, much less in a car. Being in the car is all new and foreign to her.

Choose your fantasy:

Genre of overarching story: Mythic Fantasy. Gods of old are returning to Earth to take over as a part of an ancient organization's plot to rule the world, with only 5 heroes as the hope of defeating them both. Genre of scene: Celtic Fantasy. Three of the heroes get trapped in a city in Faerie and have to rely on the treacherous fae to ever escape to save the world.

Enlarging your world:

"The city took what humans consider to be facts of reality and turned them on their heads. It was a city where a building of stone was coaxed into the shape of a tree, and where a tree was shaped to be a home that looked like a rock formation with ever-growing outcroppings. Clear glass, glittering gold, gleaming silver, refracting crystal, added on wherever the creators of the buildings decided they’d look pretty in places and ways that no human craftsman could put with tools. Some houses obviously started out as white trees but were formed into unique shapes, still growing and rooted even as they provided shelter, often large enough that the tree should fall over, accentuated with metals at random locations to give the wood some shine and glass windows seeming to be naturally part of the structure. Other buildings were made out of stone that seemed to naturally come out of the ground below like a natural rock formation. They could see that even gravity was disregarded, with paths to the buildings around them growing to match entrances that opened to the sides or even the ceilings of buildings as often as they allowed people in at the floor. Many of the paths scorned convenience in favor of whimsy, going in curves, circles, and even upside down before they reached their destinations. Despite the variety, one thing was consistent: the fog that was the city’s namesake enveloped everything. It wasn't thick enough to hide anything, instead leaving it all with a somewhat pleasant blur. Occasionally colors-deep blues, verdant greens, blood reds, and occasional glints of many others-would ripple throughout, with no apparent source. The colors refracted through the crystal, went through the glass.

What's Up People:

the race living in my city are the beings from Celtic myth known as the fae, because for my book series especially this specific race I am solely relying on the lore there's...not much in the aspects the article suggests. Traditionally they are wearing ornate Shakespearian garb, are taller and thinner than humans, and have pointed ears. The fae are masters of their environment and wielders of illusion magic (glamour) and conjuration, they don't have jobs but live as aristocrats who find amusement with human lives which they consider toys, they don't really need to eat and there's never any description of farms or whatever because food is magically conjured at their feasts (feasts which if a human eats from they will keep eating and hungering for the food of the fae forever, character in my book has this happen it's sad), their clothing is glamoured to look like it does...however, the "environment" of Ceo is essentially a trap they use on humans, as it reduces their inhibitions with its narcotic fog and thus makes us easier to play with. For culture I'll copy/paste the 7 aspects in the article and answer that way Social Organization (family units and social classes): traditionally the fae seem to mimic the human royal courts (Hence being called the Seelie or Unseelie courts), so you have the Royalty on top, the courtiers close to the throne, and commoners. Family determines class, the fae don't have the same emotional bonds that we do when it comes to family. Customs and Traditions: Decadence and debauchery are the hallmarks of fae society. Their nature is too fluid for traditions or customs of the sort. In order to deal with the boredom of immortality they crave novelty and fun...and the best source for both of them is playing with humans, wreaking havoc on our lives which seems evil to us, but they consider us like toys to be played with not as actual human beings. In Ceo they lure humans into the city as its fog slowly wears away at the human's ability to resist or control themselves, playing with them until the fog wears away everything in their minds and renders them useless. Religion: The fae are semi-divine beings themselves, nature spirits. They recognize the existence of the Tuatha De Danaan, the Celtic gods, not based on faith but because they actually interact sometimes, though they usually keep to themselves. Language: Technically Gaelic however they have the ability to both understand and be heard in every language at once. Arts and Literature: In Ceo the fae can shape their homes and the materials they use, essentially making the whole entire city a gallery of their art each one of them bringing their strange vision to life. Governing Systems: Monarchy. Economic Systems: Don't really have one, no need for one.

So You Want To Play With Magic:

Who can use it: In the larger world the magic varies with both each religion having its own magic system and also people being able to draw upon nature (I'm not really inventing anything instead drawing upon the rich preexisting cultures and traditions). The nature based one is unique because with the Return of the Gods the magic of nature has also grown back to the levels it had in myth, meaning that neopagans and other modern witches have experienced a huge surge in the powers they have called upon. In the group the leader is Áilleacht, who is descended from one of the ancient Celtic druids that escaped the Romans slaughtering them, however I'm basing my depiction of her on actual historical druids which weren't at all like the nature magic controlling archetype we associate with the term, and there's Atsa who is a Navajo (Diné as they actually call themselves) shaman guided by a spirit that has decided to remain unnamed to him (I know who it is but he's...wily [description and a hint]). The fae have their own innate magic which I already explained. What does it require: For humans it depends, honestly when it comes to these aspects I'm still partway through researching and gathering info to bring to life. For fae nothing. Where does it come from: Áilleacht, nature and ancient druidic traditions; Atsa, the spirit that chose him to be a guide to the group; fae from their supernatural nature. How do people respond to it: If humans revealed that they had such connections it depends on who they're with. The people who reject the Gods and want the world returned back the way it was before their Return with hostility, showing that they have foreign power in places serving particularly controlling Gods will have negative results, places where the power is from and accepted they would be respected, and I imagine the common person who is just going along with the flow would shrug and accept that this is a thing now. The fae are viewed with fear and respect, you don't want to be picked up by them, it's why the Irish have invented a ton of different euphemisms other than fae because simply saying that word attracts their notice. If you're actually in the know about things carrying iron because it's the only thing that can hurt them and avoiding faerie rings is a good reaction to knowing how their magic works. What does it do?/What can't it do?: Humans: still researching, fae, make illusions of any sort, eating their food or dancing with them traps you into doing those things until death, conjurations, and in Ceo shape the city however they want.

What Makes Us Who We Are:

Alex is a seemingly stereotypical muscle man from Greece with a dark past. In Greece he was a sailor with his partner as part of a fishing crew. However, out in the seas they ran across the sirens, whose enchanting song lured everyone to their deaths except Alex who remembered how Odysseus and his crew were told to plug their ears with beeswax. Lacking beeswax he put his earbuds in and blasted music at max volume so he couldn't hear the sirens...only to watch as all of his friends and the man he loved jumped off the edge of the boat to follow the song and drowned. After seeing how the presence of the Gods and their monsters caused such death, when Atsa came telling him of an opportunity to seal them away again he jumped for the chance so nobody else would suffer like he did. Because homophobia is rather rampant in Greece he doesn't reveal he isn't straight, so being tall, tan, and muscular from hard work sailing leads to women fawning over him which makes him deeply uncomfortable. He's trapped in Ceo because after Jon, a character who had most of his mind erased by the force opposing the Gods that Alex thinks they should ditch to be able to better save the world, said fae once which brings their attention Alex decided in his rather rash nature to say fuck it and repeat the word multiple times leading to the fae picking them up because they were actually willing to forgive Jon and not take them but Alex basically made them want to teach him a lesson. Because his first exposure to mythology coming back to the world was death of the guy he loved he's highly distrustful of the magic and everything else that came back with the Return.

In the first draft I ended this paragraph with "The desks stood by the windows, through which you couldn't see any but the grassland." I was trying to give details of my dorm, but that detail doesn't help me develop or help readers understand me. So I revised it by giving more details at the beginning of this paragraph, and wrote about my condition when I first came to the United States to help the reader have a better understanding of my feelings as an International student both new to the U.S. and college life.

Bash on windows tutorial with python

These stations have changed and technically no longer function like they used to. We have also gotten rid of the Mac.

Running Windows 10

I'd consider adding a link to a resource for people who want to run linux from windows. Non-programmers may not know the best way to do it. (I don't use a Windows machine for programming, or I'd suggest a good resource.)

Look at this painting by Edward Hopper. What is it conveying and how is it similar to what Nick is conveying here?

(https://www.moma.org/collection/works/79270)

Also try the command where in Windows command prompt. It does not only run in PowerShell.

Doors are capable of being walked through. The landscape can be accessed, Atwood seems to be saying. Perhaps she is even saying that wrongs can be righted. Bruhn claims that "the art that [Atwood] is now creating, with its profound elaboration of the idea of otherness (whether thematic or formal/generic, or both) and its denaturalization and reconstruction of foundational concepts inherited from modernity, the postmodern artist is extending our under- standing of that ‘large Mansion of Many Apartments’ which is ourselves, helping us to see, as Atwood puts it in the concluding words of ‘Death by Landscape,’ into the ‘holes that open inward, not like windows but like doors’" (458). Perhaps this means that the battle against colonialism must be won internally first, that looking inward first, and seeing ourselves as both the colonizer, and the colonized, as Atwood appears to be doing, is the only way to end the cycle.

We see the sickly Southern Belle

I find this very interesting. Obviously in the aftermath of the great war, Spanish flu epidemic, and great depression there was a lot of labor unrest. In the aftermath of the war the entire economy had to turn on a dime, from all war materiel, resources, and jobs to a largely private sector and the need to rebuild infrastructure in order to even have a functioning economy.

They traveled 5 months, lost food, their animals, dealt with the elements and the possibility of being killed all for a small piece of land and a cabin. It makes you wonder what they were leaving to go through all of these hardships.

Blaming the survivor is the first sign of misogyny

Evil exists through many different windows. Evil can not be pinpointed to one person, thing, or object. When the moral standard is not met, it moves to a production of regularity. The regularities of wrong doing then becomes a natural culture of society.

This is relevant.

I found this to be particularly interesting especially when she says her bed feels larger, its the bed that she sleeps in every night so I think this piece of information was put in to stress how little and unimportant she feels. along with that when she wakes up from her nap still hungry and says her room has grown cooler I think there is a deeper meaning behind that and she doesn't just mean the temperature in the room.

She keeps finding little ways to redeem him as "right."

This step was sufficient on my computer.

4.1 Choosing an Operating System

Weight: 1

Description: Knowledge of major operating systems and Linux distributions.

Key Knowledge Areas:

Windows, Mac, Linux differences Distribution life cycle management Terms and Utilities:

GUI versus command line, desktop configuration Maintenance cycles, Beta and Stable

28 WINDOW GUARDS

Window guards are devices that can be attached to the bottom of a window in order to prevent young children from falling.

Landlords in New York City have an obligation to install window guards on all windows except those giving access to fire escapes when children under 10 years of age are present. Tenants have to notify the landlord if a child under 10 is present and landlords must provide tenants with a form to request installation. Once installed, the tenant must not tamper with or remove.

For more information, see pages 22 and 23 of the Tenants’ Rights Guide.

Curator: @Zeljana_Babic

Resource used:

(Graphpad Prism, RRID:SCR_002798)

SciCrunch record: RRID:SCR_002798

Alternate resolvers: SciCrunch xml N2T identifiers.org

What is this?

Curator: @bandrow

Resource used:

(XPP-Aut: X-Windows Phase Plane plus Auto, RRID:SCR_001996)

SciCrunch record: RRID:SCR_001996

Alternate resolvers: SciCrunch xml N2T identifiers.org

What is this?

More setting details--the dining room, the wooden table, sunlight streaming in, the bowl of noodles--and some of Ai's own words: "My wife hates this one," he said. This gives a sense of Ai as a person living in the world. Note here, too, that the writer is beginning to tell the story of his encounter(s) with the artists--that is, that Osnos was there with Ai, at the table, preparing to have a conversation. This is one hint of the narrative strategy in a profile.

Herman Melville’s The Piazza has many mythological and theological referrals scattered throughout its pages. Greek mythology terms such as Elysium, Orion, and Damocles are intertwined with biblical references of Abraham, Lazarus, and the Kaaba (Holy Stone), among many others. These parabled sources spoke to the readers of his era in descriptors that would be easily recognizable and understandable. Melville’s conscious mixing of the two religious forms, showing more than one ideological opinion, is reminiscent of another author he was known to look to for inspiration, Plutarch (as spoken about in several commentary excerpts found in Melville’s Marginalia). Greek by birth, Plutarch integrated into Roman society in the middle part of his life, even changing his name to Lucius Plutarchus, and was witness to Roman acceptance of multiple forms of religion. Although Christianity was not accepted in Rome for another three and a half centuries, the well-rounded structure of the Roman society of Plutarch’s time was no doubt an influence on his work, and subsequently, on Melville. It is quite possible that some of the conscious or unconscious blending of these biblical and mythical concepts also came from Melville’s reading of Dante, translated by Rev. Henry Francis Cary, one of many books found in the Melville collection on the “Melville’s Marginalia” website.<br> Melville filled the pages of the Piazza with allusion, many of which can be lost on the modern reader. One such reference this contemporary reader may not readily connect to is Abraham. For Melville, this citation is most likely drawn from The New Testament of our Lord and Saviour Jesus Christ: Translated out of the Original Greek, and The Book of Psalms: Translated out of the Original Hebrew, published by the American Bible Society, New York, 1844, Book of John, pg. 171. A book found in Melville’s personal collection.<br> The Piazza quote where we first find mention of Abraham “And then, in the cool elysium of my northern bower, I, Lazarus in Abraham's bosom, cast down the hill a pitying glance on poor old Dives, tormented in the purgatory of his piazza to the south.”(Pg. 2), is a striking reference to the biblical ideal mixing of Greek Mythology and the Jewish faith. This entire idiom can be quite puzzling to the unknowing reviewer of Melville’s work. The belief is that Abraham is the father of all Jews, with all faithful Jews being called the sons and daughters of Abraham. They are promised that Abraham will be there to meet them when they pass away. The first part of the quote “I, Lazarus in Abraham's bosom,” is a reference to the story of Lazarus found in the Book of John 11, where Lazarus comes down with an illness and passes away (resting in the bosom of Abraham), until the fourth day of his passing, when Jesus visits his tomb and Lazarus is resurrected. Elysium is a common Greek citation alluded to in describing a heavenly destination for those who were heroes or lived virtuous and courageous lives. In Greek mythology, interestingly, the term refers to two ideally similar, yet geographically different, locales. The first of the two backdrops is an island paradise (Island of the Blessed), surrounded by a river, reigned over by Kronos, the son of Zeus. The second location was found in the underworld kingdom of Haides (or Hades), where it’s pleasing meadows were separated from Hell, also by a river. The river itself has held several names throughout the many reincarnations of the ancient concept, being known as Okeanos, or Lethe, but is best recognized and remembered as the river Styx. This place, Elysium, is the piazza Melville refers to where his narrator (Melville’s version of Lazarus) looks down from his heavenly perch upon the supposedly rich person of the town, left to suffer his poor views from his self-imposed hell.<br> The acknowledgment of “poor old Dives” is yet another harkening to the story of Lazarus. The biblical man, nicknamed Dives, was a rich man who did not offer any assistance to the hungry and sick Lazarus, and upon both men’s passing (which were close in interval to one another), Dives looked up from his sweltering confines in Hades (later renamed by the Catholic faith as purgatory) to see Lazarus in comfort at the side of Abraham, in Elysium.<br> It is of interest to note, on page 10 of The Piazza, a point of view change for the narrator. Instead of continuing to cast or see himself as Lazarus, the storyteller now shows the opposite human qualities of Poor Old Dives, referenced in the earlier quote from the story. This contrast could be Melville’s way of showing the hypocrisy inherently found in all humans. Melville’s orator denies the impoverished girl of the knowledge as to his true identity, and with this action, or inaction, also denies himself the ability to help relieve her misery. This could be a possible nod to tendencies of the intrinsic need for self-preservation being held in highest regard, whether we are consciously aware of it or not, and despite our supposed best intentions, morals, and values. Once, and if, the present-day reader is capable of deciphering Melville’s intimations, the underlying story of The Piazza becomes clearer. One of the biggest obstacles to reading classical works is understanding the author’s frame of reference. This inclination of recognizing the era in which a work was produced is often lost on the casual reader. Because of this, the writing (or alternative forms of art being studied) is frequently discarded based on lack of knowledge and understanding of its outdated references and allusions.<br> Through researching the terminology Melville used in the earlier quoted text, the reader is better able to relate to the idea, or message, behind the allusions. This analysis and interpretation, although complex and inconvenient at times, can open (for both the researcher and modern reader), countless windows to more well-rounded and higher levels of learning.<br> Researching this small quote from The Piazza allowed me to gain a much better perspective and appreciation of the entire text. This recognition is not only for the writing itself, or for the allusions used, which help the reviewer to envision the picture Melville has created, but for the arduous work ethic and passion which the modern examiner of these works must possess. My small foray into Melville’s world was mesmerizing. Looking through the actual library of his favorite texts, most being used in some form or other, to bolster his own writing, was for me, like seeing into the author’s mind. Melville’s annotations in several of the texts were a great insight into his personal character and beliefs. The intrinsic insights of Melville left behind in the pages of all these now classic works were also an interesting way for someone like me to see how an accomplished writer such as Melville looked at (both revering and loathing) many of his contemporaries.

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I feel like this part of the initial passage will act as foreshadowing for the rest of the text as in will the autobiographer even recognize himself at the end of the story

https://i.pinimg.com/originals/91/09/28/9109281bcf32c7c0da494bbb2079d7f8.jpg

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bringing a little bit of Holland to New York

You can focus on edit are: View -> Full Screen (Shifft + Alt + Enter)

Significance of the new pub's name? How about the fact that it is now windowed?

Notes the Dutch ancestry.

Williams' ending line makes allusions to themes of speed, and modernity in the reference of the car. The whole poem seems to zoom by, with its short lines and lack of punctuation. The reader is just a passenger in the car, with no control, watching from the windows as the world deteriorates.

This is exactly what bruce/adam seem to be discussing in terms of interventions and learning styles.

Flowers are an obvious symbol in this piece, one being the title and others being mentioned.. has to be an important meaning

See comments "Formation de base".

See comments made in "Formation de base".

See comments made on "Formation de base".

See comments made on page "Formation de base"

I find it extremely interesting that Jefferson and the board would make special note to cover the walkway around the lawn. This is honestly my favorite part about the lawn--I am a runner and I try to jog ten laps around the lawn every day. It's beautiful, peaceful, and makes for a perfect five mile run, and the best part is that I'm protected from the rain on rainy days! I recently toured Monticello for the first time and was fascinated with the numerous architectural advancements that Thomas Jefferson had installed in his home. He had pulleys everywhere--he could open his bedroom door and pull the curtain over his window across the room from the comfort of his bed, and had a system that sent wine bottles up to the dining room from the cellar. He also had a revolving kitchen door that would make the passage of food from the kitchen to the dining room easier, and had strategically placed windows, mirrors, and skyights around rooms in order to maximize daylight. Since I learned all of this about Monticello, I have been absolutely fascinated with the architecture at UVA, and with Jefferson's wit and attention to detail. Of course he would think to cover the path along the lawn and to have justifications for all of the other basic structures such as the two-student dormitories and pavilions for professors and lectures with a lawn of "proper breadth." It's become apparent to me that Jefferson loved simple beauty, symmetry, and convenience. I'm fascinated that I'm able to read a description of the lawn before it even existed, as its easy to take those little details for granted and this reading allows me to really appreciate the thought that went into them.

https://www.monticello.org/site/house-and-gardens/rooms-and-furnishings

This passage demonstrates the autonomy of the empire through the treatment of prisoners when Colonel Joll captures prisoners. The magistrate shows that he doesn't approve of the treatment and attempts to help the prisoners and gets"them to clean themselves" and attempts to help them, but he doesn't fully help them, he still follows the power and runs away from the problems within his society.

Sure, any open project can have vulnerabilities. But does that mean that there is a "fair and possibly growing amount of business risk in them"? Is the antidote proprietary software that's completely opaque? Microsoft Windows vs Linux?

The authors wanted to understand what the gene functions were for the alleles that were identified as involved in local adaptation. To do this they compared the genes they identified with a large database of gene functions call the GO slim annotations

Esse método parece que só funciona no funciona no windows.

Os seguintes tutoriais detalham mais esse método de instalação:

• How to Install TWRP & custom ROM without root on Galaxy S5 G900
• ROOT no Galaxy S5 SM-G900M com Android 5.0 Lollipop

This passage attempts to set expectations for the editors. By giving the editor a framework to work inside they know where to go and what to do. This should be one of the first things that the user comes across when looking for more information into editing. The content itself could be greatly improved because it seems to be too elaborate.

It was also likely the time of Windows 3.1/95/98 where people used Dial-Up though C-Slip to connect to servers via one's landline and telecommunications network. What dark days indeed were the web then...

132213

Here the author is describing the bedroom like a prison, one which the husband is making increasingly oppresive, with the editions of the 'heavy bed [...,] barred windows [...] [and] gate.'

Mirror mirror on the wall...and on the windows!

Read: the poor

read: Rich Whites

Police brutality as savior of community?????? What garbage

The Fear of the Poor

As always, deference to the rich.

for Windows

In different scenes, people will have different feelings. For example, people here will feel dark and depressed. When the windows open, the world will become sunny and beautiful.

Its changes through department stores reflect changes in society.

Early 1900 subway trains donned dual-paned windows. The top windows, or "upper doors", could be opened.

"To give their summer jackets to the wind" refers to an act by subway riders who would hang their jackets or other articles of clothing out of the "upper door" as a gesture of waving goodbye to loved ones, or simply for jovial pleasure (similar to this vintage photo of children waving their handkerchiefs out the window of their train in Chicago, ca. 1902).

Remove

This number is constantly repeated throughout the text. There are three windows, it was three o'clock when Mr. Enfield was returning home, etc. The number three is a significant number in Christianity and its subtle repetition can be hinting at the conflict between science and religion that is notable in this era.

Only noting a typo in case Dr. Graham is looking for these. The content is clear.

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We run in the cloud and in the age of docker, we can control the environment fully. The problem arises with a few narrow cases where we need windows, but people have systematically misused that: I have once read how some people ran a Jetty server to host an OSLC adaptor inside an Eclipse IDE (my brain goes puff every moment I recall this).

For me (Windows 10) git pull -u origin master gave me error error: unknown switch `u'. git pull origin master worked.

"Everyone in the streets and the windows said, "Oh, how fine are the Emperor's new clothes! Don't they fit him to perfection? And see his long train!" Nobody would confess that he couldn't see anything, for that would prove him either unfit for his position, or a fool. No costume the Emperor had worn before was ever such a complete success."

note I'm not testing on windows

Don't worry about this, your system isn't that old.

Check this before you start -- perhaps already fixed?

Highly relevant section

Highly relevant section.

Also highly relevant section

Not practical because your system is custom-built.

Probably worth checking this. I can walk you through it, but it'll take a little more digging for me.

I am certain that Windows 10 is also included; this article must have been written before W10 was released.

Does NOT apply, you don't need to use this as a startup drive.

Had to read this entire section out loud dramatic monologue style.

This is an interesting point. Archival research is a huge pain; it's part of the labour of the traditional historian. But perhaps some of the labour of the modern/digital historian ought to be reworking the system and making archival visits less necessary by depositing their research online. Yes, it's work. But it's necessary upkeep. If IT guys never took the time to update office computers past Windows 95, then they're going to have to fix a lot more busted computers. If historians never update archival material to digital formats, they're going to have to visit a lot more archives.

We are responsible for securing our physical spaces by ensuring our windows are closed, doors are locked, and other openings re secured. Nonetheless, under the law, the physical space bounded within the house is considered private property, and breaking into this space is a crime—burglary—punishable by law.

How would this extend to cyberspace, where the boundaries are not so clearly drawn? Who "owns" the data? Even if we are supposed to "own" the data, it is stored physically elsewhere and managed by someone else—to what extent are they responsible for protecting our information?

https://www.youtube.com/watch?v=88jkB1V6N9w

Video explaining how the WanaCry worm works, explained in a very understandable way.