59 Matching Annotations
  1. Mar 2024
    1. Crazy how open everybody is. In my country, if people spoke this freely about drugs use, the police would raid their homes and put them in jail.

      actually that is what is called a sane country

      "sane countries" would ban only the actual bad drugs: alcohol, tobacco, fentanyl, methadone, oxycodone, krokodil, all chemotherapy drugs for cancer, all vaccines, pasteurized milk, ... also, all legal drugs would have zero taxes for the next 1 million years to say "sorry for our war on drugs".

      but well, "sane" is a very subjective thing: my paradise is your hell. thats why we need tribalism: every tribe has his own rules, and if i dont like my tribe, i can move to a different tribe. tribalism aka "small countries"

    1. Driving under the influence (DUI) is the offense of driving, operating, or being in control of a vehicle while impaired by alcohol or drugs (including recreational drugs and those prescribed by physicians), to a level that renders the driver incapable of operating a motor vehicle safely.[1] Multiple other terms are used for the offense in various jurisdictions.

      Driving under influence (DUI) under alcohol or drugs

  2. Oct 2023
    1. . Two clinically important cardiac drugs ouabain and digitalis, inhibit the Na+-K+-ATPase by binding to the extracellular domain. This enzyme can consume significant amounts of cellular ATP energy. The Na+-K+-ATPase can be coupled to various other transporters, such as those involved in transport of glucose (see later).

      Oubain Digitalis

      Both Cardiac Drugs

  3. Feb 2023
    1. The effects of four reference antihistamines: ketotifen, diphenhydramine, chlorpheniramine and pyrilamine and of astemizole, a new potent and long-acting antihistamine, were studied on 16 hr sleep-wakefulness patterns in the same dogs. Using a computer-based on-line analysis and automatic stage classification, a differentiation was made between wakefulness, transition to sleep (drowsiness), slow wave sleep and rapid eye movement (REM) sleep. The reference antihistamines significantly increased non-REM sleep. The reference antihistamines significantly increased non-REM sleep: diphenhydramine and chlorpheniramine increased drowsiness, ketotifen increased slow-wave sleep and pyrilamine increased both. All, but astemizole, significantly prolonged the latency to the first REM period, prolonged the interval between successive REM periods and suppressed the total amount of REM sleep. With all antihistamines, the effects were most pronounced for the first 4 hr and there was no within-night rebound. Chlorpheniramine had long-lasting effects throughout the night, especially on REM sleep. The effects on non-REM sleep might be due to a blockage of brain histamine H1 receptors, whereas the effects on REM sleep might be due to the anticholinergic properties of the antihistamines. Astemizole was devoid of any significant effect on the sleep-wakefulness pattern, in spite of its long-lasting antihistamine effects, suggesting that the common clinical side-effects of antihistamines, such as sedation and dryness of mucosal surfaces, will be lacking.

      It may be worth exploring the improvements on non-REP sleep, particularly if they are increasing slow wave (deep) sleep. This is particularly true, since newer generations of antihistamines aren't anticholinergic.

    1. It’s different for everyone. I have found it to be amazing. It has given me energy, drive, motivation, euphoria, happiness, mood enhancement, and more endurance. It also makes music super awesome to listen to, with a physical and mental high. The difference bw this and any benzo is that they target different things. Benzodiazepines target a binding point found on certain GABA-A receptors and it enhances GABA by modulating it (increasing GABA’s overall effectiveness and activity), and there are more than one binding points that benzodiazepines can bind to (BZD1, BZD2, etc) that cause different effects like sedation, hypnotic, muscle relaxation, anxiolytic, etc. Phenibut is a moderately mild-average GABA-B receptor agonist, meaning it can boost the amount of GABA released. It’s main effects come from it being like a gabapentinoid, which means it also binds to the GABA-B calcium channels and blocks them. This causes different signals to happen due to the channels being open or closed. Because of this, and because Phenibut isn’t identical to gabapentin or pregabalin (both gabapentinoids), it causes different signals to influence other neurotransmitters. It can be said that it causes a boost of dopamine as well as natural endorphins. It has a more stimulating effect at the right doses than any benzo, which is more sedating. Benzos only modulate GABA at the GABA-A receptor sites, but Phenibut can sometimes activate both GABA-B and GABA-A, giving a unique effect as well. The people who use it recreationally enjoy the body and mental high as well as the increase in sociability since a lot of people take it for social anxiety and going to parties so they can be more talkative and outgoing. Phenibut can also be used for insomnia and sleep issues. It is very effective in my experience. I have chronic insomnia and even with sleep meds I still wake up a bunch of times a night. Phenibut has allowed me to sleep thru the entire night once except I did wake up after the sun came up around 7am because I had to pee really badly. Otherwise, I went right back to sleep. I also noticed I can feel more refreshed on less sleep, which is good if you are a parent to young children who get up super early. Another use that is interesting is using it before exercise and going to the gym to work out. Phenibut can give you more endurance and enjoyment doing exercise, so you benefit more from each workout. This could be from the increased release of endorphins. This is one thing I really enjoy doing myself and have noticed really great benefits as well as it putting me in a real motivated state and mood and I feel like I could workout forever it seems! I definitely notice the difference when I go to the gym without taking it (because I am taking a break from it to lower tolerance). One thing to keep in mind is once you find the ideal therapeutic dose, you won’t get the same effects every time you take it if you use it every day. Tolerance to some of the actions like euphoria and body high tend to disappear. This is why a lot of users suggest taking it only 1–3 days a week MAXIMUM. It is possible to become dependent on Phenibut, but the withdrawal is not supposed to be as intense and life-threatening like benzos are (due to seizures, etc). A high dose is considered anything more than 2g/day. Therapeutic doses can be as low as 250–750mg/day. Considering this is a prescription medication used in Russia, it does have some psychiatric use. People taking therapeutic doses are less likely to have extreme reactions or build rapid tolerance to Phenibut. There are some people who take Phenibut from unreliable sources that claim they do not feel anything on it that is noticeable even at high doses for a first time (1g-2g). It’s just like some people do not respond to certain benzodiazepines (one seems to work the best for different people as well as what kind of dose is needed), as well as SSRIs, which all are selective serotonin reuptake inhibitors, because each one may be selective to different subtypes of serotonin (5HT) receptors, which are quite numerous, each one and its variations seem to do different things. Some people don’t respond to SSRIs at all (2/3 of people apparently according to statistics), but the rest that do respond find that they really have helped them and changed their lives by boosting their moods, etc. Are you going to feel Phenibut the first time you take it? Since it is not controlled in the USA, for example, it is sold as a “supplement” or found on “nootropic” websites. There are a lot of good vendors out there just like there are a lot of bad ones do to the supplement field being so uncontrolled compared to prescription drugs, which are controlled and regulated by the FDA & DEA to be a certain level of purity. So if you get a bad batch, you may find yourself feeling nothing. But if you get a good batch (I’ve found at least 2 that I would definitely call awesome supplement/nootropic suppliers online), you should be more inclined to feel something at least, unless you are one of those genetic exceptions that don’t benefit from this type of agonist/channel blocking. Be sure to start lower dose and if you don’t feel anything in 4 hours at least, then you could try another dose. But really don’t go overboard thinking a huge dose will be good for you. Some people report getting nauseous, overly sleepy, and having other reactions you don’t want. You don’t want to pass out and wake up having to throw up over and over. Don’t mix it with alcohol, as alcohol tends to modulate GABA in various ways as well as some other neurotransmitters and hormones. They can create a combined effect. Interestingly, some people use Phenibut to give them the same desired effects of alcohol (ability to socialize, being more talkative and clever, going out with friends to have fun at a club or whatever, etc) without the messiness of it (getting drunk, dizzy, nauseous, throwing up, headaches, sour stomach, hangovers, etc). Be sure to respect it like you would any prescription medication, since it is one in certain Countries, even if it is just a supplement in yours. Proper titration of the ideal dose as well as cycling (taking days off or even taking a break for a while from all use) are really important. These can affect the potency of Phenibut each time you use it.
  4. Dec 2022
    1. That is, people who reported tendencies toward more excitement and motivation to engage in pleasurable experiences experienced greater AMPH-related increases in Positive Mood

      ...people who like excitement get more pleasure out of amphetamine (speed).

  5. Oct 2022
  6. Sep 2022
  7. Jun 2022
    1. 97.8 Percent of Mass Shootings Are Linked to This

      What is the total number of Citizens using antidepressant drugs? What were the underlying conditions of those who did perform mass shootings?

      What does the data suggest here? Are there identifiable trends and correlations? Is this predictable? Or is it largely random?

  8. May 2022
    1. Jesuit’s bark, also known to us as quinine, was an important anti-malarial drug. According to Molly Farrell, an associate professor of English and the history of science who first reported on Franklin’s abortion entry in Slate, it was also “mistakenly thought to be an abortifacient.” 
  9. Mar 2022
  10. Nov 2021
    1. I am, by calling, a dealer in words; and words are, of course, the most powerful drug used by mankind. Not only do words infect, ergotise, narcotise, and paralyse, but they enter into and colour the minutest cells of the brain, very much as madder mixed with a stag’s food at the Zoo colours the growth of the animal’s antlers.

      [...] words are, of course, the most powerful drug used by mankind.<br/> —Rudyard Kipling (1865-1936) in "Surgeons and the Soul" address at the annual dinner of the Royal College of Surgeons, London, February 14, 1923.

      See Also

    1. Some 775 people with Covid took part in the study. Among the half of patients taking molnupiravir twice a day, 7.3 per cent were admitted to hospital over the course of 30 days. This compares with 14.1 per cent of the second group of patients who were given a placebo pill.

      interesant

  11. Sep 2021
  12. Jul 2021
    1. Sergio: Why did your family migrate to the US?Rodolfo: The reason why my family moved to the US was because both my grandfather and my biological fathers struggled with addiction, with alcoholism and drug abuse. They were just not very... Mostly my biological father, he really wasn't always there, and he was always very violent towards my mother. My mother had me when she was 14 years old. When she got pregnant everybody decided well, okay, she messed up. She is this, that, like very, very taboo. She wasn't really accepted in the family anymore. It wasn't so much my family and I moving to the US, it was just my mother and I when she was 16 and I was two and a half years old. They weren't really interested in what was going on with me or my mother. She just wanted a better quality of life for her and for myself.Rodolfo: In Mexico at 16 years old, with no type of education past probably middle school, she knew she wasn't gonna get very far. I guess she made that decision in order to have a better quality of life for her and myself, she went on. She was 16, and I don't know how she did it. I don't know the details and all that, but she met the right people, or she got in contact with the right people, and she went over there. She went to the United States. To this day, I still remember a lot of the things, even though I was very, very young. It's something that I always tell everybody that I meet, it's not just for this interview.Rodolfo: I always remember the bad things that happened or the very... I don't know if it's because it had such a big impact in my life and my mother's life or just because of how everything was set up. I remember everything that happened from start to finish. From the beginning where we got picked up, to being in the desert. I still remember eating cereal with water. It was... I don't know, it was very, very... I feel like it was... it obviously had an impact psychologically, because I still just have a lot of anxiety when I'm in certain places that I'm really accustomed to. A two, three year old in the middle of the desert, it definitely had to have an impact on me.Sergio: How old were you when that happened?Rodolfo: I was two and a half years old, so that's why I'm saying it's very odd for me to be able to remember that at a very, very young age. It wasn't only that, just even when I was here, when I was two, two and a half, I used to remember asking my mom certain memories that I had. She would say, "Oh you were one year old, one and a half years old, how did you remember that?" It was always very, like a violent, violent memory that I had. It was more so like my father being drunk or high or whatever and coming in the house. Taking any little money my mom made for the week, in order for him to keep on doing what he was doing. Just coming in and just tearing up the place.

      Mexico before the US, Mexican Childhood, Memories, Family; Mexico before the US, Migration from Mexico, Reasons, Violence, Domestic Violence, Border Crossing, Desert

    1. Claudia: In what ways do you think that being in the U.S. all that time shaped who you are?Yosell: I think the only way I can put it really is just being strong. Because basically you got to learn how to mature in a faster way than you'd probably do it here. I've seen a couple of family members or friends here that are like 30 years old and they're still living with their dad and mom. They're just like not doing anything for their life, and opposed of people out there, most of them that I do know were just living by themselves and doing their thing. I'd say out there it's probably not that good because you’d get, because most of the people would get into some kind of a drug addiction or something like that. I’d say, here, here it'd be probably the same, but out there it'd be easier to make money. Here it's a lot harder. That's probably what's the difference here to there. That's what I'm saying, I think out there you learn how to be strong. When you come here, you're just like, "Oh." most people get depressed or frustrated here. Others actually know how to move on and continue. That's probably how I see it.

      Reflections, The United States; Feelings

  13. Jun 2021
    1. να παίρνει κόκα, να κάνει ενέσεις ηρωίνης, έστω κι ελεγχόμενα,

      Δεν υπάρχει ελεγχόμενη ένεση!

      Εδώ φανερώνεται το έλλειμμα γνώσεων στο θέμα, απόρροια της φοβικής στάσης της Δεξιάς. Γιατί υπάρχει μεγάλη απόσταση ανάμεσα στο δοκιμάζω ναρκωτικά, κι στο παρακάμπτω τα σωματικά μου φίλτρα για να εισάγω μέσα μου μια ουσία μέσω μιας ιατρικής πράξης (ένεση).

      Αυτή η απόσταση χωρίζει την ζωή από τον θάνατο. Απόσταση που την γνωρίζουν συνήθως οι αριστεροί, λογω της περιεργειάς τους.

    1. And that's the day I got caught up with the blunt in my ear and the security caught me. From there on, I had to go to court fighting the cases and then basically I just like—

      Time in US - encounters with police - arrest Drug - taking drugs

    2. When you smoke, it makes you feel like nothing is important. All your problems go away basically. And it was just like a coping mechanism to just go on every day with my life. I felt like if I didn't have that, there was no point. My life was whack.... There was one point in time that I had to smoke before I do something fun.

      Time in US - taking drugs - coping mechanism - addiction

  14. May 2021
  15. Mar 2021
  16. Feb 2021
    1. Scientific research on psychedelics begannearly 70 years ago, with over 1,000 clinicalarticles being written between 1950 and 1972showing promising results

      It is pretty intriguing that there was no stigmatisation between these years about psychedelics while today there is even a huge stigmatisation of psychedelics in the scientific field. There are some scientists who want to rediscover these positive effcts of psychedelics. There are few studies showing that psychedelics such as LSD, DMT and especially Psilocybin have an incredible antidepressive effect. The psychedelic Renaissance will come soon (hopefully)

      Also I do have the assumption that the goverment inhibited psychedelic drugs for an evil/profitable reason. Some people say that psychedelics are the antidote of propaganda :)

    2. Moreover, psychedelics are particularlypromising for enhancing cognitive functions, asthey appear to be nontoxic and medically safe,even when consumed at standard hallucino-genic dosages (Bogenschutz & Johnson, 2016),producing no dependence or addiction in ani-mals or humans (Nichols, 2004;Nichols, 2016;Nichols & Grob, 2018)

      As we can see, there was no good reason to inhibit psychedelic drugs. It rather helps you to overcome your Depression, Anxiety, PTSD, CPTSD and even Alzheimer as a prevention.

  17. Jul 2020
    1. My own happiness has been trampled under foot; my own love has been torn from me. Shall I live to see a happiness of others, which is of my making–a love renewed, which is of my bringing back? Oh merciful Death, let me see it before your arms enfold me, before your voice whispers to me, “Rest at last!”

      Although this is a very sweet sentiment made by Ezra, it hints to a sadder truth that Ezra just wants to do good but suffers under the judgement of people due to his addiction. Drugs have been just as much (perhaps more) of a curse to Ezra as the Diamond has been for the characters in this story.

  18. Aug 2019
  19. Mar 2019
    1. “Most Japanese people see cannabis as a subculture of Japan but they’re wrong. For thousands of years, cannabis has been at the very heart of Japanese culture,” Japan’s leading expert on cannabis, Takayasu Junichi, told the Asia Pacific Journal in an interview.

      This is quite something.

    2. Japan today has some of the harshest drug laws of any advanced democracy. If you are found in possession of cannabis in Japan for personal use you could receive a maximum prison sentence of five years, and if you are caught growing it, you can be sent to prison for up to seven years. Each year, the laws are enforced against 2000 people, who are brutally publicly shamed before, during and after their prison sentence.[2] For example, when the actress Saya Takagi was caught with cannabis, all reruns of the dramas she appeared on – like the popular detective series Aibo - were scrubbed from the TV schedules.[3] She had written the theme song for another TV show: it was immediately ditched. Or to give another example, when a rugby player for Japan’s national team was caught with the drug, he was banned from ever playing again, and the electronics giant Toshiba suspended all sponsorship of his regional team.[4] To be associated with cannabis in Japan is to be destroyed.

      Whoa! To be associated with cannabis in Japan does seem equal to public shaming. This is probably the least helpful way to try and make people not use drugs. Also, addiction is a disease.

  20. Nov 2018
  21. Sep 2018
    1. However, courts might go further and address the concern that, even where government regulation of cognitive enhancement drugs is rooted in legitimate safety concerns, this should not—by itself—give the government authority to restrict individuals’ mental freedom or “cognitive liberty” far more than is necessary to address those safety concerns. Perhaps, for example, government has imposed a complete ban where something less restrictive will satisfy the safety concerns it is worried about. For example, the state might instead institute a “gatekeeper” system in which a doctor must assess and discuss risks for a particular individual before drugs are prescribed or require a mandatory course on side effects before use of cognitive enhancement drugs.

      I believe that this solution to the paragraph directly above it, directly contradicts itself. If the Government bans the use of a drug not because it can make someone happier/better, but because it can have potentially negative or harmful side affects, then this solution is impossible. If the government deems some as potentially harmful then in more cases than not it most probably is. In this way no government could rationally come to this solution rather than the one above it. It would be obscure for a Government to allow a person who is educated about the dangers of a product to choose to use it. In the Government's and the medical professional's eyes this person would not be in their 'right mind'.. How then, could they ever allow someone who they do not deem 'in their right mind' to use a potentially hazardous drug?

    1. No. It’s not you. You were different before. – I’m still the same person, Lin. – I wasn’t, when I was on it. I did things I would never do. – Those things saved your life. – But they weren’t me. – Yes, they were. No, the way it works… – I know how it works. I get it. I totally get it. You feel invincible.

      The rhetoric of this passage raises a very important question. Are the people who are taking this drug really themselves still? If this was just a thought enhancing drug then perhaps this would be the case, however it does more than just make the user hyper-intelligent. The fact that this drug changes people's attitudes and their personalities proves that these people aren't themselves. On the other hand a hyper-intelligence may not directly change the person, but may enable them because a higher intelligence could reasonably lead to a higher confidence and a higher rationale of thinking.

  22. Aug 2018
  23. Apr 2017
    1. The ability of story (prose and poetry) to trans-form the storyteller and the listener into some-thing or someone else is shamanistic

      Easy connection with Rickert and the notions of shamanistic transcendence of the body.

  24. Jul 2016
    1. alcohol, tobacco, and hard drugs, most people who use marijuana can stop taking it when they want, while experiencing only minor withdrawal symptoms.

      But the best thing about taking marijuana is that you are able to stop not like the people that drink alcohol or other type of things. This matters to do that all they do is smoke because they could stop if they want to. One time me and my sister stop a man to ask him if he drink ans he told us the does and he had tried to stop bus he couldn't because his body was to use to it.

    2. Some hashish users like the feeling of these visions and thoughts, while others may find them scary. However, people rarely get hallucinations after smoking or eating cannabis.

      Most of the people smoke because they like it not because they have to do it or they going to things at home. This really matters to the teens that are smoking life because they don't want there kids to be on those types of things. My friend told me one time that her mom us to get mad when she us to go home high.

    3. This means that if a person starts taking heroin, meth, or cocaine, that person's body will physically need to keep taking the drug. If they try to stop using the drug, they may become very sick.

      That is the most bad thing about drugs that people will get addicted to it and will not stop using it. This matter to a lot of families because they don't want their kids to get addicted to drugs at a young age. something that i remember is when my brother started to smoke we all was mad at him in the family because we didn't want him to be addicted to the drugs.

    4. According to a 1999 report by the Institute of Medicine, marijuana (especially THC) can decrease pain; control nausea and vomiting; and improve appetite.

      That is probably by people ate smoking because if make the pain go away. This will matter to people that is sick because the only way they could not feel the pain is by smoking. This connect to my life because I have family members that are sick

    5. As of 1995, scientists had not shown that smoking marijuana causes lung cancer, even in people who smoke a lot of marijuana for a long time.

      there had been people saying that marijuana may save people from having cancer. This matter to so many people in this word because there is people dying of cancer. This connects to my life because my grandmother was sick of cancer.

    6. Uruguay was the first country in the world to make it legal to grow, sell, and use cannabis.

      people will go to the place just to get some drugs and then try to get it in there country. This will matter to the people that don't take drugs because they may not like the way it smell when they pass by people that don't smoke. Something i hurt about drugs was that it may kill people.

    7. A person who is intoxicated ("high" or "stoned") from marijuana could get hurt or killed in an accident if they drive a car.

      most of the time they will get killed because when you drunk you cant move as fast like in the regula there is so many people thas is dieing because of drugs. This matters to me because i have friends that have died because of drugs. Something that i know about drugs is that it may save you or kill you

    8. As of 2016, many different countries and some states in the United States have made it legal for people with certain medical problems to use marijuana as a medicine.

      so if people think that marijuana is good for people that have certain medical problems why they not laten people smoke if is so call good for people body. This matters to me because some of my family is sick. something that i huart that people that got cancer.

    9. Marijuana is an illegal drug in many countries

      but in some countries is not illegal that is why there is so many kids in the word that be taking drugs because they be getting it from another state most of the time people from a another state be the one bring in the drugs. this matter to me because there in a lot of kids from honduras that take drugs. something that i hurt was that you don't have to be 21 to get drugs

    1. they was a lot of people that was tell to try drugs by friends family,girlfriend, boyfriend ,but most of the time they will do it yest to be cool.it matters because most of the people is losing there family for using drugs.it connect to me becuse when my family fist fond out that i was smoking they got mad at me.

    2. Drugs effects your memory even if u have been taking them for a long amount of time or taking them for a short amount of time.

    3. Depends on the amount of drugs u take. less drugs u take might just speed u up and make u feel really active. Stronger amount will just make it slow sluggish and tired and even more amount of drugs can kill you.

    1. “Even if their friends do not smoke marijuana, but do not disapprove of its use, teens are more likely to give it a try.”

      They don't have to see it with family or friends they got facebook and facebook is all about drugs and sex. This matters because they may go and have sex to because they wanna try the things they see. This connect to my life because my little sister got facebook and if she see something about weed she may go try it.

    2. He says that because teens see friends or see family smoking weed they are going to do it. Or because they live in a neighborhood where they have too much activity going on around the neighborhood, they might smoke weed.

      most of the time that is the reason by most of the teens be smoking weed because they see it with there family or friends. It matters to me because if people get to know that they smoking because they see it in there house they may have a ACS case. something i heard about weed is that it may kill you.

    1. can benefit from knowing that marijuana users who use because they are bored are more likely to use certain other drugs,

      Most of the people use marijuana because they are all the time having problems in their family or they are going through something.This is important because be get to know why is people taking drugs it connect to me because one of my family members was going to the type of drugs problemes.

  25. Jun 2016
    1. “Last Friday, I took acid and mushrooms/I did not transcend, I felt like a walking piece of shit/in a stupid-looking jacket.”
  26. May 2016
    1. that doesn't mean the drugs can't be immensely profitable. Treanda is an orphan drug but also Teva's second-best seller, racking up $740 million in sales last year, according to Teva's annual report.

      Isn't the whole point of an orphan drug classification that of limited commercial viability? So if they're not commercially viable how are they profitable?

  27. Apr 2016
    1. First of all, people aren’t uniformly good at splitting pills. Dose deviation is common among pill-splitters and that’s an issue for drugs that need to be maintained in a narrow range. Worse, many pills are in extended release formulations that break down when split. Splitting a time-released pill in half can cause an overdose. The list goes on: cutting all your pills in half before you need them could cause them to become ineffective, people often forget to cut them and take a double dose, etc.
    1. Some have called for more lenient sentencing for drug offenders

      It would be interesting to see if this might change in light of recent revelations uncovered from members of Nixon administration that the war on drugs was motivated to render the black community and hippie voices diminished.

  28. Dec 2015
    1. The idea was to pinpoint the doctors prescribing the most pain medication and target them for the company’s marketing onslaught. That the databases couldn’t distinguish between doctors who were prescribing more pain meds because they were seeing more patients with chronic pain or were simply looser with their signatures didn’t matter to Purdue.
  29. Mar 2015
  30. Oct 2013
    1. For as the medicines which men apply to the bodies of their fellow-men are of no avail except God gives them virtue (who can heal without their aid, though they cannot without His), and yet they are applied; and if it be done from a sense of duty, it is esteemed a work of mercy or benevolence; so the aids of teaching, applied through the instrumentality of man, are of advantage to the soul only when God works to make them of advantage, who could give the gospel to man even without the help or agency of men

      All things, even rhetoric and medicine, have effect only through the divine