https://www.aslobcomesclean.com/about-me/

Is 1 hour necessary? The Maxwell protocol DNA Purification from Microorganisms in Water Samples mentions 70C for 10 min with ProK and RNAseA..?

Helbig, Daniela K. “Ruminant Machines: A Twentieth-Century Episode in the Material History of Ideas.” JHI Blog (blog), April 17, 2019. https://jhiblog.org/2019/04/17/ruminant-machines-a-twentieth-century-episode-in-the-material-history-of-ideas/.

https://en.wikipedia.org/wiki/G._K._Chesterton

The video shows the productivity books which Sheldon used to help design his system including 99u's Manage Your Day-To-Day, Unsubscribe by Jocelyn K. Glei, The One Thing by Gary Keller, Getting Things Done by David Allen, Deep Work by Cal Newport, and Atomic Habits by James Clear.

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Recommended Source

Under the "More on Philosophies of Copyright" section, I recommended adding the scholarly article by Chinese scholar Peter K. Yu that explains how Chinese philosophy of Yin-Yang can address the contradictions in effecting or eliminating intellectual property laws. One of the contradictions is in intellectual property laws protecting individual rights while challenging sustainability efforts for future generations (as climate change destroys more natural resources.

Yu, Peter K., Intellectual Property, Asian Philosophy and the Yin-Yang School (November 19, 2015). WIPO Journal, Vol. 7, pp. 1-15, 2015, Texas A&M University School of Law Legal Studies Research Paper No. 16-70, Available at SSRN: https://ssrn.com/abstract=2693420

Below is a short excerpt from the article that details Chinese philosophical thought on IP and sustainability:

"Another area of intellectual property law and policy that has made intergenerational equity questions salient concerns the debates involving intellectual property and sustainable development. Although this mode of development did not garner major international attention until after the 1992 Earth Summit in Rio de Janeiro, the Yin-Yang school of philosophy—which “offers a normative model with balance, harmony, and sustainability as ideals”—provides important insight into sustainable development."

In the December 1906 issue of System, a magazine which would eventually become Bloomberg Business Week), W. K. Kellogg, the President of the Toasted Corn Flake Company is quoted touting the invaluable nature of the Shaw-Walker filing system at a time when his company was using 640 drawers of their system.

Coincidence that Schmidt shows a journalist Luhmann's zettelkasten in 2015 and asks if they're disappointed?

It's reasonably likely that he'd already read ZKII 9/8,3.

see: https://hypothes.is/a/GFj15IcbEe21OIMwT2TOJA

in the article which follows below, there's an explicit mention of this specific zettel, so the question on priority here is closed.

Ashinoff and Abu-Akel propose an equivalence between "flow" and "hyperfocus". They mention later in this paper that "flow" is more often used in positive psychology literature whereas "hyperfocus" is more often used in psychiatric literature. Even so, they also qualify that they may just appear to be the same (ie, descriptively similar) while having a different cause (ie, mechanism of action).

This never happened in this way. Another example of how #socsoft became marketing almost exlusively. With the exeception perhaps of async tools like Slack (2013) or Yammer (2008, still exists as part of MS), although filtering is not their point, their users may use it that way. The whole #socsoft for org internal k-work never got much traction. Still a lost opportunity imo. Tools probably need to better fit existing culture/communication styles in org and be internal, but being created as separate place external with its own assumptions.

Helbig, Daniela K. “Life without Toothache: Hans Blumenberg’s Zettelkasten and History of Science as Theoretical Attitude.” Journal of the History of Ideas 80, no. 1 (2019): 91–112. https://doi.org/10.1353/jhi.2019.0005

Helbig indicates that Hans Blumenberg had a "near obsessive reliance on [his Zettelkasten as] writing machinery.

in Life without Toothache, Daniela K. Helbig looks at the role of Hans Blumenberg's Zettelkasten as the site of his theoretical development as a historian and philosopher.

Struktura syndetyczna (syndetic structure; Buckland 1992: 285), czyli struktura spajająca, wiążąca, odsyłająca, np. „zob.” lub „zob. też”.

Hjørland 2007: https://arkiv.inf.ku.dk//KoLifeboat/CONCEPTS/syndetic_structure.htm

https://hyp.is/zEc8Gj3XEe2IiMO2YE8RTw/arkiv.inf.ku.dk//KoLifeboat/CONCEPTS/syndetic_structure.htm

ReconfigBehSci. (2022, January 2). RT @trishgreenhalgh: A few tweets on masks for kids (thanks @dgurdasani1). US schools were 3.5 x more likely to have COVID-19 outbreaks if… [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1477614232556515331

OK, let's break down these terms: * multicenter: the study was conducted studying animals at multiple clinics/locations * prospective: study subjects are enrolled and followed BEFORE the disease or the outcome is observed (in this case the painful procedure/analgesic response. Prospective studies tend to be less prone to bias, compared to retrospective studies (like evaluating historical patient records of prior disase/treatment/outcome). * randomized: enrolled subjects are assigned to treatment or control groups randomly. Randomization can be an effective way to minimize intentional or unintentional bias in a study. For example, in a non-randomized study an investigator might (intentionally or unintentionally) place all of the younger subjects in the control group and the older subjects in the treatment group. Now you have two things that could contribute to a difference between controls and treatments, the actual treatment AND AGE. So if there was an improvement in the treatment group, which thing did it, treatment or age? Randomization reduces the occurrence of biases like that. * masked : this is also called blinded. In masking, one or more categories of study workers are blinded as to whether subjects are in the treatment group or the control group. I'd have to look at the full experimental write-up to know exactly who was blinded, but at a minimum the study workers assessing the analgesia should be blinded as to whether they are observing a treatment, or a control animal. This can be complicated! A vehicle control cat is unlikely to be dysphoric/euphoric, so if I am a study worker and I see a dysphoric cat, I will likely be biased to assume that it has been treated with drug, and that could in turn bias my assessment of its pain. * vehicle control : this is a form of placebo control. the treatment group gets vehicle+drug, the control group gets only vehicle. You will also read about "active control". In this case it is an intramuscular injection of bupe. This allows a comparison between all the things that can interfere with transdermal absorption, and an administration of bupe that bypasses the vagaries of transdermal absorption and lets the investigators know what a more reliably absorbed, roughly equivalent dose, is capable of. Placebo controls and vehicle controls are also related to masking/blinding. In the ideal world, almost no one should know whether a patient got the control treatment or the test treatment, until the study is completed and the data analyzed. This reduces bias in assessing the effect of the treatment. * pilot : a pilot study is an early study, often used to explore dose, timing, effectiveness in a smaller number of animals to aid in designing a larger subsequent study.

Remember, the two basic things that FDA requires for approval are 1) actual evidence that establishes the drug is an effective treatment for the specific indications in the application (in this case post operative analgesia in cats) and 2) typical use of the drug is unlikely to cause injury that is disproportionate to the risk that the disease presents. For example, most anticancer drugs may cause injury, but the diseases that they treat have a much greater risk of injury if left untreated. But there would be a much higher expectation of safety in a drug to treat kennel cough, a disease which is rarely fatal and often self-limiting. So here, in this data we'll see studies designed to provide evidence of effectiveness, and studies designed to provide evidence of safety.

This drug is not exactly an earth-shaking discovery. "BuTrans", from the notorious Purdue Pharma (in a legal settlement, Purdue Pharma agreed to disband as a business) was FDA approved for humans in 1981, is a transdermal buprenorphine patch.

Beyond our scope, don't worry about this.

Inclusion and Exclusion criteria are important! Remember, you are trying to keep the treatment group and control group as similar to each other as possible.

To me, the executive summary (not sure why they call it that!) seems to be pretty dialed-down for a non technical audience. This is a great skill to get better at, although at points the basic language can get a bit confusing

This concept is called dose proportionality, and it is a really handy thing to know. What they are saying here is that beyond a dose of 30mg/cat you lose dose proportionality. This implies that below that dose, if you double the dose you should see approximately a doubling of plasma concentration--That's dose proportionality!

This is a nice & clear explanation of "flip-flop kinetics"! Far more common is the situation in which absorption is fast, compared to the slower elimination. In that far more common scenario, half-life (aka terminal half-life) is driven by clearance. Here, the rate of absorption is so slow that whatever drug is absorbed is quickly distributed and cleared (but of course during that process some drug gets to its CNS targets and binds (tightly!) to them.

Not surprising since bupe is really, really lipophilic.

this is an example where oversimplification distorts the facts. "bind as strongly" is not accurate, and it disagrees with "high binding affinity" in the previous paragraph. Bupe does bind with very high affinity to the mu opioid receptor. It is a partial agonist because that tight binding is not capable of causing the conformational change in the receptor that is necessary to produce a maximal receptor response. The ability to fully activate a receptor is not a function of the tightness of binding (if that was the case naloxone, which also binds tightly, would be a full agonist). It is a function of whether the binding induces the 3-d changes in the receptor that cause it to signal its activation to the interior of the cell.

Pl.: Budapesti Szépművészeti Múzeum Könyvtár

L’autisme est un trouble neuro-développemental caractérisé par des anomalies ==>problème de définition du champ dans l’interaction sociale, dans la communication et dans le comportement (activités répétitives et stéréotypées). Ces anomalies causent, pour la personne atteinte d’autisme, de grandes difficultés cognitives ==>elles ne sont pas conséquence des interactions sociales ni des stéréotypies mais liées au développent du cerveau

Qu’est-ce que le trouble du spectre de l’autisme : Jadhav, M., & Schaepper, M. A. (2021, août). What is Autism Spectrum Disorder? American Psychiatric Association. Consulté le 11 mars 2022, à l’adresse https://www.psychiatry.org/patients-families/autism/what-is-autism-spectrum-disorderDiagnosis of Autism Spectrum Disorders : signs and symptoms on Social communication & Restricted interests and repetitive behaviors

Morava K-theory is an invariant.

https://www.youtube.com/watch?v=rhgwIhB58PA

Learning styles have been debunked.

Learning styles: V.A.R.K. model originated by Neil Flemiing stands for:

• visual
• auditory
• reading/writing
• kinesthetic

References:

Pashler, H., McDaniel, M., Rohrer, D., & Bjork, R. (2008). Learning styles: Concepts and evidence. Psychological science in the public interest, 9(3), 105-119. — https://ve42.co/Pashler2008

Willingham, D. T., Hughes, E. M., & Dobolyi, D. G. (2015). The scientific status of learning styles theories. Teaching of Psychology, 42(3), 266-271. — https://ve42.co/Willingham

Massa, L. J., & Mayer, R. E. (2006). Testing the ATI hypothesis: Should multimedia instruction accommodate verbalizer-visualizer cognitive style?. Learning and Individual Differences, 16(4), 321-335. — https://ve42.co/Massa2006

Riener, C., & Willingham, D. (2010). The myth of learning styles. Change: The magazine of higher learning, 42(5), 32-35.— https://ve42.co/Riener2010

Husmann, P. R., & O'Loughlin, V. D. (2019). Another nail in the coffin for learning styles? Disparities among undergraduate anatomy students’ study strategies, class performance, and reported VARK learning styles. Anatomical sciences education, 12(1), 6-19. — https://ve42.co/Husmann2019

Snider, V. E., & Roehl, R. (2007). Teachers’ beliefs about pedagogy and related issues. Psychology in the Schools, 44, 873–886. doi:10.1002/pits.20272 — https://ve42.co/Snider2007

Fleming, N., & Baume, D. (2006). Learning Styles Again: VARKing up the right tree!. Educational developments, 7(4), 4. — https://ve42.co/Fleming2006

Rogowsky, B. A., Calhoun, B. M., & Tallal, P. (2015). Matching learning style to instructional method: Effects on comprehension. Journal of educational psychology, 107(1), 64. — https://ve42.co/Rogowskyetal

Coffield, Frank; Moseley, David; Hall, Elaine; Ecclestone, Kathryn (2004). — https://ve42.co/Coffield2004

Furey, W. (2020). THE STUBBORN MYTH OF LEARNING STYLES. Education Next, 20(3), 8-13. — https://ve42.co/Furey2020

Dunn, R., Beaudry, J. S., & Klavas, A. (2002). Survey of research on learning styles. California Journal of Science Education II (2). — https://ve42.co/Dunn2002

Suggested Annotated Reading from the I Annotate 2021 Keynote: Courtney McClellan

s

Our week 8 module on Web 2.0 and the gig economy discussed this in more depth, and Barron alludes to this dynamic elsewhere in the article when describing both the typical user of an app like seamless and the typical profile of the gig economy worker who actually delivers their food - I appreciate the critiques of app design and user infantilization he is making here, but the article could have also discussed in more depth how these design choices help these companies to obfuscate and divert attention from the way they impact people besides the consumer. There is a whole class people whose primary interaction with these apps is on the back end- as struggling small business owners dependent on positive yelp reviews, delivery people, and rideshare drivers - maybe that is outside the purview of this article, but it would have been nice to see this angle explored a bit more.

Title

Trump Back-to-School Threats Pressure Educators Fearing Covid. (n.d.). Retrieved September 3, 2020, from https://news.bloomberglaw.com/coronavirus/trump-back-to-school-threats-pressure-educators-fearing-covid-1

Adam Kucharski on Twitter: “I’m getting asked more about the ‘k’ parameter that describes variation in the reproduction number, R (i.e. describes superspreading). But what does this parameter actually mean? A short statistical thread... 1/” / Twitter. (n.d.). Twitter. Retrieved June 4, 2020, from https://twitter.com/AdamJKucharski/status/1267737631481364480

This is a Wikipedia page about the book.

This is the Wikipedia page.

This is the Wikipedia page.

europium has been popularly used for the red flash and light in smart phones.

when they add the zinc dust to the europium to separate it can become flammable and dangerous.

When they scan a bill they are looking for the europium flash.

the properties of Phosphorus.

How Phosphorus is used in a smartphone.

Potential uses in phone batteries and silicon wafers As semi conductors.

lead is radioactive, so when you touch it, it can effect your body.

when you use compressed air to remove lead dust, can blow the lead into the air, causing people to breath it in.

Potassium mines in 3rd world countries.

Top antimony producing countries

How antimony is found in nature

Chemical properties of antimony

Physical properties of antimony

Negative health effects of repeated exposure to antimony

Uses of antimony in technology

Mined in Many different places

Needed for normal function in Iphone.

This is where Lanthanum is mined and where it comes from in the mines

lead is a poor electricity conductor but good and used in phone batteries.

the source of gallium.

The mining and processing of nickel has one of the biggest effects on global warming out of 63 metals.

Lanthanum Toxins have been leaking into the ground water which people use for tap water.

solutions

desertification - prevention and restoration

Mining is contaminating our water sources and water is one of the most important things for survival.

We need to find a way to prevent pipeline spills because they happen way too frequently and they are horrible for the environment.

So different kinds of mining use different tunnel systems, how do we decide which kind is best in each situation?

Good information about environmental issues

This site is the homepage of the Tech Infusion program at Arizona State University (ASU). Housed within ASU's Mary Lou Fulton Teachers College, Tech Infusion is a technology integration curriculum for Pre-K-12 teacher candidates. Through coursework and hands-on practices, teacher candidates are prepared to use technology fluently and innovatively for teaching and learning. The program integrates research, ISTE Standards, and the TPACK (Technological Pedagogical Content Knowledge) framework around effective technology integration. This website provides technology-infusion resources for course developers, instructors, and current and future educators. Examples include research articles, edtech tool tutorials, lesson plans, and outlines of the curriculum. Rating: 9/10

Coffey argues the effectiveness of online literature discussions in the elementary classroom. Addressing both synchronous and asynchronous environments, she suggests that computer-based discussions can enhance understanding of literature and promote community within the classroom.

10/10

This manual, published by Hanover Research, outlines theory and practice of technology integration in the K-12 classroom and provides key strategies for professional development to equip teachers to successfully integrate technology.

10/10

The authors present the benefits of coaching in professional development for educators in today's technologically advanced classrooms. Of particular interest is the explanation of the different methods of coaching: executive, coactive, cognitive, and instructional. They suggest that coaching provides more successful outcomes than single workshops and stress that finding the correct method for each situation and organization is crucial.

10/10

Data from annotation informing teaching practices, understanding of learning, success, at admin level.

Real-time grading/assessment for reading = annotation

And note just assessment, but presence: peer learning; teacher-student feedback, ...

A Brief History of Reading Instruction. Includes references to studies that support phonics as the best method for teaching reading and writing. Free textbook for phonics instruction: https://elink.io/p/free-phonics-books-98c2d4e

there was no pollution caused because of the mines safety measures.

cold weather can cause pipe lines the break.

The Highland Valley copper mine in Canada leaked polluted water into near by lake.

this is a benefit

the ions in the lithium is the competent that is found in phones.

That's interesting!

This shows that there was gold in Ethiopia!

true stuuff

Why does China need so much.

Goddamn they should start recylcling

some info about the ore and where it is mined

how neodymium is refined

A description of cobalt.

Where to find cobalt on periodic table and cobalt's atomic number.

info about how mines work

how large the coperbelt is

They seem to offer up mining contracts very easily.

its weird how people are able to exploit these people legally, and if not legally than how have people not made an effort to stop them?

I wonder if the people at the top of the company even know that this is going on with there "employees"

this is where cobalt comes from

Personal Learning Environments (PLE) applied to K-12 classroom

personalized mobile learning solutions to create effective learning paths This appears to blend personalized learning and mobile learning. It is prepared by a specific vendor, MagicBox, so they might be assumed to have their own agenda. This page describes some of the affordances of personalized mobile learning, such as the capacity to track and presumably respond to learner preferences. rating 2/5

This should be taught throughout k-12 schooling. Learnng this in college was super helpful but it was taught a little late for me. I know now how to choose sources that present good information but growing up I wouldnt have been able to do that

This article describes how school districts who wish to integrate more technology into their classrooms should approach the integration. Rating: 4/5

Evaluation, when it is not asked for, and when it has consequences as it does in school, is a threat. It narrows the mind... it inhibits new learning, new insights, and creative thought—the very processes that some people think school is supposed to promote. -- Peter Gray

. . .

Why is it clear to us that it's degrading and objectifying to measure and rank a girl’s physical body on a numeric scale, but we think it’s perfectly okay to measure and rank her mind that way?

. . .

what an oak tree actually needs is not your opinion but soil and water and light and air, and what a child needs is love and stories and tools and conversation and support and guidance and access to nature and culture and the world. If a kid asks for your feedback, by all means you can give it; it would be impolite not to. But what we should be measuring and comparing is not our children but the quality of the learning environments we provide for them.

I don't think James ever claimed he was solving "the problems in public education." How about he's shining a light on ways increased public funding could stimulate public education?

How much internet time is too much? Skill set should revolve around communication, sharing, social behaviors, not so much internet at this age- maybe 30 mins a day could be dedicated to these projects though?

Pearson out of US k-12 market

Raf Camora: Anthrazit [oo]

VÖ: 1.9.2017

AppleMusic / iTunes