61 Matching Annotations
  1. Last 7 days
    1. As we are currently using it, the term includes the organization, study, modification, and execution of processes and process structures. Whereas concept structuring and symbol structuring together represent the language component of our augmentation means, process structuring represents the methodology component (plus a little more, actually). There has been enough previous discussion of process structures that we need not describe the notion here, beyond perhaps an example or two. The individual processes (or actions) of my hands and fingers have to be cooperatively organized if the typewriter is to do my bidding. My successive actions throughout my working day are meant to cooperate toward a certain over-all professional goal.
    2. Before we pursue further direct discussion of the H-LAM/T system, let us examine some background material. Consider the following historical progression in the development of our intellectual capabilities:2c4a 2c4b (1) Concept Manipulation—Humans rose above the lower forms of life by evolving the biological capability for developing abstractions and concepts. They could manipulate these concepts within their minds to a certain extent, and think about situations in the abstract. Their mental capabilities allowed them to develop general concepts from specific instances, predict specific instances from general concepts, associate concepts, remember them, etc. We speak here of concepts in their raw, unverbalized form. For example, a person letting a door swing shut behind him suddenly visualizes the person who follows him carrying a cup of hot coffee and some sticky pastries. Of all the aspects of the pending event, the spilling of the coffee and the squashing of the pastry somehow are abstracted immediately, and associated with a concept of personal responsibility and a dislike for these consequences. But a solution comes to mind immediately as an image of a quick stop and an arm stab back toward the door, with motion and timing that could prevent the collision, and the solution is accepted and enacted. With only non-symbolic concept manipulation, we could probably build primitive shelter, evolve strategies of war and hunt, play games, and make practical jokes. But further powers of intellectual effectiveness are implicit in this stage of biological evolution (the same stage we are in today).2c4b1 (2) Symbol Manipulation—Humans made another great step forward when they learned to represent particular concepts in their minds with specific symbols. Here we temporarily disregard communicative speech and writing, and consider only the direct value to the individual of being able to do his heavy thinking by mentally manipulating symbols instead of the more unwieldly concepts which they represent. Consider, for instance, the mental difficulty involved in herding twenty-seven sheep if, instead of remembering one cardinal number and occasionally counting, we had to remember what each sheep looked like, so that if the flock seemed too small we could visualize each one and check whether or not it was there.2c4b2 (3) Manual, External, Symbol Manipulation—Another significant step toward harnessing the biologically evolved mental capabilities in pursuit of comprehension and problem solutions came with the development of the means for externalizing some of the symbol-manipulation activity, particularly in graphical representation. This supplemented the individual's memory and ability to visualize. (We are not concerned here with the value derived from human cooperation made possible by speech and writing, both forms of external symbol manipulation. We speak of the manual means of making graphical representations of symbols—a stick and sand, pencil and paper and eraser, straight edge or compass, and so on.) It is principally this kind of means for external symbol manipulation that has been associated with the evolution of the individual's present way of doing his concept manipulation (thinking).
  2. Dec 2019
    1. Melody is a UI library for building JavaScript applications
  3. Jul 2019
    1. w them. On the 1st of April it rained and melted the ice, and in the early part of the day, which was very foggy, I heard a stray goose groping about over the pond and cackling as if lost, or like the spirit

      Thoreau uses description and narration here to paint a picture of the natural world around him, the sounds and imagery. I found it interesting that he compared the cackling of the goose to the "spirit of the fog."

  4. Apr 2019
  5. Jan 2019
    1. Like them, all frames basically define parts of our percep­tual environment as irrelevant, thus separating that which we attend in a focused manner from all the out-of-frame experience44 that we leave "in the background" and ignore.

      Evokes Geertz' advice in ethnographic thick description to focus on the details in order to make sense of the situational context and place people/events in an interpretative frame.

  6. Dec 2018
    1. A repertoire of very general, made-in-the-academy concepts and systems of concepts-"integration," "rationalization," "symbol," "ideology," "ethos," "revolution," "identity," "metaphor," "structure," "ritual," "world view," "actor," "function," "sacred," and, of course, "culture" itself-is woven into the body of thick-description ethnography in the hope of rendering mere occurrences scientifically eloquent

      Concepts that communicate thick description.

    2. Such a view of how theory functions in an interpretive science suggests that the distinction, relative in any case, that appears in the experimental or observational sciences between "descrip­tion" and "explanation" appears here as one, even more relative, between "inscription" ("thick description") and "specification" ("diagnosis")-between setting down the meaning particular social actions have for the actors whose actions they are, and stating, as explicitly as we can manage, what the knowledge thus attained demonstrates about the society in which it is found, and beyond that, about social life as such. Our double task is to uncover the conceptual struc­tures that inform our subjects' acts, the "said" of social discourse, and to construct a system of analysis in whose terms what is generic to those structures, what belongs to them because they are what they are, will stand out against the other determinants of human behavior. In ethnog­raphy, the office of theory is to provide a vocabulary in which what symbolic action has to say about itself-that is, about the role of culture in human life-can be expressed.

      The nut of Geertz' argument: Ethnographic theory building is about developing conceptual structures applicable to other settings in order to understand and analyze culture (human life, symbolic action, and beliefs). Thick description and its interpretation provides the framework for making theoretical distinctions.

    3. conceptualization is directed toward the task of generating interpretations of matters already in hand, not toward projecting outcomes of experimental manipulations or deducing future states of a determined system. But that does not mean that theory has only to fit (or, more carefully, to generate cogent interpre­tations of) realities past; it has also to survive-intellectually survive-realities to come. Although we formulate our interpretation of an outburst of winking or an instance of sheep­raiding after its occurrence, sometimes long after, the theoretical framework in terms of which such an interpretation is made must be capable of continuing to yield defensible interpretations as new social phenomena swim into view

      Cultural theory is not predictive but interpretative. Thick description helps to determine whether a theory can be further elaborated or is no longer useful for describing/interpreting behavior.

    4. The first is the need for theory to stay rather closer to the ground than tends to be the case in sciences more able to give themselves over to imaginative abstraction. Only short flights of ratiocination tend to be effective in anthropology; longer ones tend to drift off into logical dreams, academic bemusements with formal symmetry. The whole point of a semiotic approach to culture is, as I have said, to aid us in gaining access to the conceptual world in which our subjects live so that we can, in some extended sense of the term, converse with them. The tension between the pull of this need to penetrate an unfamiliar universe of symbolic action and the requirements of technical advance in the theory of culture, between the need to grasp and the need to analyze, is, as a result, both necessarily great and essentially irremovable.

      Challenges of theory development about cultural understandings. The tension between semiotic/symbolic approaches that require interpretation (grasp) versus methods that are grounded in analysis.

      "...the essential task of theory building here is not to codify abstract regularities but to make thick description possible, not to generalize across cases but to generalize within them."

    5. Ethnographic findings are not privileged, just particular: another country heard from. To regard them as anything more (or anything less) than that distorts both them and their implications, which are far profounder than mere primitivity, for social theory.

      This tension exists in HCI as well.

      Interpreted data vs empirical data and how each is systematically analyzed.

    6. Cultural analysis is (or should be) guessing at meanings, assessing the guesses, and drawing explanatory conclusions from the better guesses, not discovering the Continent of Meaning and mapping out its bodiless landscape. So, there are three characteristics of ethnographic description: it is interpretive; what it is interpretive of is the flow of social discourse; and the interpreting involved consists in trying to rescue the "said" of such discourse from its perishing occasions and fix it in perusable terms ... But there is, in addition, a fourth characteristic of such description, at least as I practice it: it is microscopic.

      Ethnographic description:

      • Interpretation/sensemaking/meaning/explanation • Interpret the flow of social discourse • Contextualize the discourse • Focus on details

    7. But as the standard answer to our question has been, "He observes, he records, he analyzes"-a kind of veni, vidi, vici conception of the matter-it may have more deep-going consequences than are at first apparent, not the least of which is that distinguishing these three phases of knowledge­seeking may not, as a matter of fact, normally be possible; and, indeed, as autonomous "opera­tions" they may not in fact exist

      Thick description as knowledge seeking, not simply recorded observation.

    8. But it is an aim to which a semiotic concept of culture is peculiarly well adapted. As interworked systems of construable signs (what, ignor­ing provincial usages, I would call symbols), culture is not a power, something to which social events, behaviors, institutions, or processes can be causally attributed; it is a context, some-· thing within which they can be intelligibly-that is, thickly-described ....

      The primary point of the thick description -- to describe culture as a context in a systematized interpretation of human behavior.

    9. rom this view of what culture is follows a view equally assured, of what describing it is-the writing out of systematic rules, an ethnographic algorithm, which, if followed, would make it possible so to operate, to pass (physical appearance aside) for a native. In such a way, extreme subjectivism is married to extreme formalism, with the expected result: an explosion of debate as to whether particular analyses (which come in the form of taxonomies, paradigms, tables, trees, and other ingenuities) reflect what the natives "really" think or are merely clever simula­tions, logically equivalent but substantively different, of what they think. ...

      Geertz critique of the behaviorist fallacy also seems to touch on Bowker and Star's argument that meaningful classification comes from within a group not an external observer.

    10. One is to imagine that culture is a self-contained "super-organic" reality with forces and purposes of its own; that is, to reify it. Another is to claim that it consists in the brute pattern of behavioral events we observe in fact to occur in some identifiable community or other; that is, to reduce it.

      Geertz warns about the danger of reducing or reifying culture. While this may have been a debate in anthropology in 1973 (hopefully resolved), it still seems to resonate in HCI today between the factions of technological determinism and social constructionism

    11. Once human behavior is seen as (most of the time; there are true twitches) symbolic action-action which, like phonation in speech, pigment in painting, line in writing, or sonance in music, signifies-the question as to whether culture is patterned conduct or a frame of mind, or even the two somehow mixed together, loses sense

      Action/human behavior as a symbol to illuminate "what's important" not just what exists or can be observed.

    12. Here, in our text, such sorting would begin with distinguishing the three unlike frames of interpretation ingredient in the situation, Jewish, Berber, and French, and would then move on to show how (and why) at that time, in that place, their copresence produced a situation in which systematic misunderstanding reduced traditional form to social farce.

      Example of what needs to be considered to produce a thick description.

    13. Analysis, then, is sorting out the structures of signification-what Ryle called established codes, a somewhat misleading expression, for it makes the enterprise sound too much like that of the cipher clerk when it is much more like that of the literary critic-and determining their social ground and import.

      "sorting out the structures of signification ... and determining their social ground and import" seems akin to Bowker and Star's discussion about the social, ethical, and moral aspects of classification.

    14. Quoted raw, a note in a bottle, this passage conveys, as any similar one similarly presented would do, a fair sense of how much goes into ethnographic description of even the most elemental sort-how extraordinarily "thick" it is. In finished anthropological writings, includ­ing those collected here, this fact-that what we call our data are really our own constructions of other people's constructions of what they and their compatriots are up to-is obscured because most of what we need to comprehend a particular event, ritual, custom, idea, or what­ever is insinuated as background information before the thing itself is directly examined.

      Deeper exploration of just how "thick" these descriptions (interpretations of interpretations) can be versus observation.

    15. But the point is that between what Ryle calls the "thin description" of what the rehearser (parodist, winker, twitcher ... ) is doing ("rapidly contracting his right eyelids") and the "thick description" of what he is doing ("practicing a burlesque of a friend faking a wink to deceive an innocent into thinking a conspiracy is in motion") lies the object of ethnography: a stratified hierarchy of meaningful structures in terms of which twitches, winks, fake-winks, parodies, rehearsals of parodies are produced, perceived, and interpreted, and without which they would not (not even the zero-form twitches, which, as a cultural category, are as much nonwinks as winks are nontwiches) in fact exist, no matter what anyone did or didn't do with his eyelids

      Definition of thick vs thin description in ethnography.

      For HCI, ethnographic description (and ethnomethodology) help to generate the necessary symbols, sensemaking, and motivations to better interpret and understand human behavior with a specific cultural context. Helps to put a much finer point on simple observation.

  7. Nov 2018
  8. Oct 2018
  9. Sep 2018
  10. Aug 2018
  11. course-computational-literary-analysis.netlify.com course-computational-literary-analysis.netlify.com
    1. All his long years of service gone for nothing!

      This sentence shows that Mr. Doran is very unwilling to marry Polly, let alone love her. The writer spends a lot of words to describe how regretful Mr. Doran is to emphasize that the marriage between Mr. Doran and Polly must be unhappy. Thus, the writer debunks the incalculable consequences that Mrs. Mooney's interference to Polly's marriage cause through side description.

  12. Feb 2018
  13. Sep 2017
    1. IfwefocusonhowpeopleenactthemselvesassubjectsofpowerthroughtheInternet,itinvolvesinvestigatinghowpeopleuselanguagetodescribethemselvesandtheirrelationstoothersandhowlanguagesummonsthemasspeakingbeings.Toputitdifferently,itinvolvesinvestigatinghowpeopledothingswithwordsandwordswiththingstoenactthemselves.ItalsomeansaddressinghowpeopleunderstandthemselvesassubjectsofpowerwhenactingthroughtheInternet.
    1. Or that the dog at the bottom of the stairs keeps having mild strokes, which cause her to tilt her head inquisitively and also to fall over

      I find this description of the dog very upsetting, because she cares about her dog and to have to see her dog go through these strokes has to be very difficult. Jo Ann also does a good job of helping me understand what the stroke looks like, in her eyes, when it occurs

  14. Mar 2017
    1. EFO is a data-driven application ontology that reuses concepts from over 30 ontologies,

      this is what EFO is. it links multiple ontologies together and unifies different data using different ontologies

    1. There was a pause as cars hooted on the road, jutka-drivers swore at their horses and the babble of the crowd agitated the semi-darkness of the park.

      Long description slows down the pace of reading, reflecting the substantial pause in the narrated event.

  15. Jun 2016
    1. Caulobothrium anacolum sp. n.(Figs. 12-13, 19)DESCRIPTION (n = number of measurementsused): Strobila acraspedote, apolytic, 6.8-15.4mm long, composed of 13-32 (n = 30) pro-glottids. Scolex with four pedicellated, quad-rate bothridia; pedicels 50-150 long, wider atbothridium than at trunk; bothridia 648-804long by 324-700 wide, with 22-23 transversesepta forming 23—24 total loculi; median longi-tudinal septum absent. Cephalic peduncle120-360 long. Immature proglotticls widerthan long; mature ones 1.14-2.54 mm long by0.38 mm wide. Testes in anterior % of pro-glottid, 34-45 (x = 41, 11 = 20) in number,54-138 in diameter; 10-14 (12) postporally,5-7 (6) preporally, 18-27 (23) antiporally.Cirrus sac in anterior % of proglottid, 144-216long by 108-178 wide, containing spined ever-sible cirrus. Genital atrium inconspicuous.Genital pore 19-29% of proglottid length fromanterior end, irregularly alternating. Vaginaanterior to cirrus sac; vaginal sphincter present;posterior portion expanded to form seminalreceptacle. Ovary bilobed in frontal view, X-shaped in cross-section, follicular, 144-312 longby 96—300 \vide at isthmus in tci'minal pro-glottids. Vitelline follicles extending length ofproglottid, 12-60 in diameter.
    2. Rhinebothrium magniphallum sp. n.(Figs. 15, 17)DESCRIPTION (n = number of measurementsused): Strobila acraspedote, apolytic, 2.28-3.06 mm long, composed of 8-12 (n = 40)proglottids. Scolex composed of four pedicel-lated, bilobed, elongate bothridia with indis-tinct hingelike constriction between lobes;pedicels up to 22 long; bothridia 264-488 longby 128—144 wide, divided transversely by 15-17 transverse septa forming 16-18 total loculi;median longitudinal septum absent. Cephalicpeduncle 24-60 long. Immature proglottidswider than long to longer than wide; matureones 444-912 long by 108-204 wide. Testesin anterior MJ of proglottid, in two longitudinalrows, 10-15 (x = 12, n = 21) in number, 17—41 in diameter. Cirrus sac at midproglottid,145-195 long by 46—75 wide, containing spinedeversible cirrus. Genital atrium prominent.Genital pore 36-48% of proglottid length fromanterior end, irregularly alternating. Vaginaanterior to cirrus sac; v a g i n al sphincter present.Ovary near posterior end of proglottid, lobesfused posteriorly, X-shaped in cross-section,116-238 long by 29-87 wide at isthmus interminal proglottids. Vitelline follicles extend-ing entire length of proglottid, may be conflu-ent posterior to ovary, 10-35 in diameter.HOST: Himantura schmardae.SITE: Spiral valve.LOCALITY: Caribbean Sea, 15 km. west ofLa Cienaga, Magdalena, Colombia.HOLOTYPE: USNM Helm. Coll. No. 73965.Paratypes: USNM Helm. Coll. No. 73966;Univ. Neb. S t a te Mus., H. W. Manter Lab. N o.20262.ETYMOLOGY: The species name refers to therelative size of the cirrus s a c.Rhinebothrium magniphallum resembles R.monodi Euzet, 1954 (17) and R. scobinaeEuzet and Carvajal, 1973 (19) in number ofbothridial loculi; R. hawaiiensis Comford, 1974(11-13), R. euzeti Williams, 1958 (12) andR. cadenati Euzet, 1954 (12-14) in number oftestes per proglottid; and R. scobinae and R.cadenati in lacking a median longitudinal sep-tum in each bothridium. The cirrus sac of R.magniphallum is relatively much larger thanthat of any other species.

      Rhinebothrium magniphallum

  16. Apr 2016
    1. Hier sehen Sie auf einen Blick, welche Betriebe des Netzwerkes "Demonstrationsbetriebe ökologischer Landbau" in Ihrer Nähe liegen. Die blauen und gelben Punkte zeigen an, wie viele Demonstrationsbetriebe sich in einer bestimmten Region befinden. Ein Klick darauf zoomt die Ansicht näher heran. Die roten Fähnchen markieren jeweils die genaue Lage der Demonstrationsbetriebe, ein Klick darauf führt Sie zum Betriebsporträt.
  17. Feb 2016
    1. Christoph Goertz. He’s hip in a professorial, cardigan/jeans kind of way. He’s tall and lanky and white-haired, forty-seven years old, with an elegant trace of accent from his native Germany.

      The narrator is describing a character so that the readers can visualize how he looks like.

  18. Dec 2015
    1. Now, let’s move on. I want to correct a misconception on your part—a spatial misconception. you are feeling that you are moving forward along a path, building upon a foundation of knowledge and ability to reason, which you have developed and exercised in the past. This is not the case. The fact is that you are moving backwards on the path which you have come. This is because, to a large degree, your path took you away from your Being and into a three-dimensional frame of reference. You are, so to speak, relaxing back out of that thinking process—that finite, reasoning, intellectual structure which you felt was getting you somewhere in a progressive sense. Our conversation right now is not the result of a thinking process at all. When you stand at the Door as the Door, the Wisdom, the Truth, the Knowledge that flows through and as your conscious experience of Being, is not the result of thought processes, nor of reasoning. Because It continues to flow on past you, It truly does not become a stored body of knowledge from which you may draw in the future. Standing as the Door means that, in this so-called “future,” whatever Knowledge and Understanding is applicable to the unfolding at that time will be there in exactly the same manner that It is here right now. You see, Paul, we are beginning to redefine what constitutes your conscious experience of Being.

      Description of how Being operates.

      Not by storing knowledge...

    1. Now, I want to correct a misconception on your part. Your ability to reason and think is not the equivalent of the three-dimensional frame of reference. Your thought processes and reasoning processes are not to be ignored. We would not be communicating at this very moment if you did not have the means to translate the meanings I am communicating into words and phrases. It is only by virtue of the fact that you have imagination, reason, perspicacity—all of the various capacities and functions of Consciousness—that you are able to correctly translate that which unfolds to you. This is true whether it is coming from me, or from that Place wherein you directly experience the Reality of Being. We run into trouble when we stand away from the Door, and begin our thinking or thought processes from their standpoint, and then extrapolate and come to conclusions without going within and being as Conscious Being. You see, Being unfolds Itself as meaning, not as language. It is through the function of Reason and Imagination that language is brought into play, for the purpose of verbalizing these infinite meanings which Being is unfolding. You do have a right to answers which will identify the Absolute Oneness of Being throughout your entire experience of Being.

      Question: what is the best Tag to use when referring to challenges that arise in life - here, Raj, speaks of running into trouble when we begin our thought process apart from conscious Being.

      Raj is correcting Paul's Belief, or misconception, regarding reason and thinking.

      He also further describes Being.

    1. The process of “observing” is the Conscious Function of Mind. That which is being “observed” is Mind’s Universal Function of being Conscious Being. In other words, Being—Mind—by being, projects or manifests Itself, and is the Observing of the Process. It is the projector, the image, and the observing of it. The more you learn to be out from Mind—rather than believing that you are some part of the image on the screen—the more you will become aware of the total harmony of the total process or function that constitutes your Being. What you apparently do, and what apparently is done to you, will become apparent as being totally harmonious. There will be no sense or experience of separation, lack, division, or opposition. The conscious experience of Being is all that is going on. The details, the drama, the story line, et cetera, are incidental to the whole Process.

      Description of Conscious Being.

  19. Nov 2015
    1. You are the masculine figure, the point at which Life emerges into manifestation. You are also the feminine figure, that out of which the form is formed. You are the Life, and you are the Substance by means of which Life is Self-expressed. It is a total and complete Life process. Your Being is the Father/Mother God referred to in one of your prayers. As I said, all of you is always present.

      Map this out - come up with an image of Being, Totality, and Creativity.

      This is a further description of Being; masculine, feminine, Life, and the Substance by which Life is expressed.

    1. On the other hand, Identity, when It is perceived to be the expression of the Universal, omnipresent divine Mind or Intelligence, is capable of expressing Itself on a sustained basis—so sustained that the word “eternal” is the only word that describes It. It is so substantial by virtue of Its Nature as Intelligence, that It is called Omnipotent.

      Identity is the expression of the Universal Divine Mind.

    2. There is only one infinite Life/Principle, one infinite Identity, infinitely expressed and seen as all that exists. It is what constitutes the center and circumference of Being—Your Self as you experience It, Susan’s Self as she experiences It, and my Self as I experience It. Its omnipotence or strength is constituted of Its absolute omnipresent Integrity, which is Its Intelligent Nature. it is not thrilling or exciting when contemplated from an egotistical standpoint. But It is satisfying in ways that are so meaningful that they cannot compare to the “thrills” of the ego. It also has this benefit: The satisfaction is eternal and unchanging.

      There is only one infinity Identity infinitely expressed and seen as all that exists. It is what makes up the center and circumference of Being.

      Identity is not exciting when compared from an egotistical standpoint.

    1. Now, when I said that Substance is Energy, I did not mean that It was energy in the sense that your scientists measure and call electrical or atomic energy. it is Energy in the sense that It is Light. Even so, It is not Light in the sense of It being that energy which emanates from your sun. In terms of the manner in which It is experienced Fourth-dimensionally, it is very similar. It radiates, glows, or fluoresces, yet these are very poor words to describe it. Light, as it is experienced objectively, is seen only as it reflects off of an object. At night, when you look out into the objective universe and there is nothing in the sky to reflect light, the sky appears to be black, except where light is either reflected or generated as planets and stars. Fourth-dimensionally speaking, the Substance which is Light is illumined, apparently, from within. It is not a reflected light. The apparent space between specific manifestations of Mind will not be found to be dark, because the Fourth-dimensional equivalent of what appears to be empty space in the three-dimensional frame of reference, is filled with the omnipresent Substance of Being. Therefore, you will find that even “empty space” is filled with that living Illumination of the Universal Substance which is Light. Further, it must be understood that this Substance which is Light is Love, living Love. You have experienced this already in illumination, and so I know you understand what I am saying.

      Holy, do I every perceive it different than this, Batman!!

      This sounds similar to descriptions of the "other side" given by NDE'ers.

    1. PAUL: Okay, Raj, I’m alone… RAJ: Although you caught it, I want to amplify on it. “Alone” is a three-dimensional concept implying that there’s everyone else, and then there’s “me.” This is ego. You’ve got to be alert. Notice that your body is having physical sensations that you recognize as feeling disheartened, worried, or fearful. Notice that it has an intent; it is not just a feeling. It is there to motivate you to “do” something objective. Notice that in observing it, the I that is You that is observing is clear, unmoved, and at peace. To be alone with one’s Being is to be totally Present, Universally Present, without one iota projected “out there.” It is to have no other Mind but God. Notice that Its intent is not directed at you. Notice that It does not try to coerce you. Notice that you are not aware of a separate selfhood upon which It can act. Don’t try to reason it out or figure it out. Just notice It. At the present moment, you are not completely free of the inclination to believe that you are what ego says, and that you are in a pickle. On the other hand, you are not buying the story, either. Just notice. You have never had to go all the way before, so this is new territory for you. But, as long as you don’t relinquish any of the territory you have gained so far, you will find yourself moving forward. You will not lose any ground. Okay, Let’s get back to your opening statement.

      The belief that I can be alone is ego. Notice the feeling and intent of being alone. It is there to motivate you to do something objective.

      This presents a deeper perspective than I've previously considered. The Experience of aloneness stemming from ego generates a physical feeling and an intent directed outward.

      And now he contrasts that with being alone with one's Being. This is being totally Present with nothing projected outward. Being Present is to have no other Mind but God...

      Isn't this a description of Conscious Being given in terms of Presence?

      Paul is still inclined to believe what the ego says - but he does not buy it completely. Moving forward implies that the temptation to agree with ego decreases.

    1. You are truly beginning to experience the Fourth- and third-dimensional frames of reference existing side by side. You are able to observe yourself, and actually experience what seems to you to be yourself, being depressed. At the same time, you are able to experience your Self as being totally clear, at peace, in harmony with your Being, and not emotionally vexed in any way.

      A description of simultaneous experience of 3d and 4d frame of reference.

    1. March 19, 1982 Friday

      This chapter is description of how to heal a challenge in life - whatever it is. It outlines a practice to employ in times of challenge.

  20. Oct 2015
    1. Paul, it is impossible for your world to become integrated if you do not understand what the Substance of that Totality is. This is why we are discussing this point this morning. The only Substance there is throughout the Universe—and throughout all dimensions—is Light. This Light, in Its various aspects, is Life, Truth, Principle, Mind, Soul, and Spirit. It is also Intelligence and Substance. In everything you do, I want you to begin to be conscious of this idea that all there is to you—and all there is to everything—is this Light of Living Love. There are not two things going on. This Light is eternally living Itself as the intelligent expression of Conscious Experience, universally and specifically.

      My world cannot be healed unless I come to understand that the totality of all things is Light, which is Love.

      Here he equates Light to Life, Truth, Principle, Mind, Soul, and Spirit.

      He gives Paul an exercise. To begin to be conscious, in everything he does, that all there is to him - and to everything - is Living Love (God!!!!)

      There is not two things going on, there is not the perceived drama of life and Living Love. And this is where the practice is important because it the insanity of the world seems to be true.

    2. RAJ: This Light energy, which is constituted of the Christ-consciousness—God’s view of Himself—is what constitutes your consciousness and your experience, Totally and Completely. you must understand that there is nothing else going on—no other Presence but this Light. It is the Light of Living Love.

      Christ Consciousness is God's view of Himself, is what constitutes Light.

      Light constitutes your consciousness and experience totally and completely.

      There is nothing else going on - no other Presence but this Light, the Light of Living Love.

      This is a description of Christ and of Heaven.

    3. RAJ: The delight of Life is the signal which indicates the successful completion or Awakening in individual thought. This is because it indicates the amalgamation or connection of the Alpha and Omega—the inside and the outside—the spiritual and material—the Fourth Dimension with the first three as Conscious Experience. I know that this is very difficult for you to put up with, because you feel there are more pressing needs, but if you will bear with me a little longer, it will be worth your while.

      Awakening is complete when you delight in Life. Delight indicates union of spiritual and material, the inside and outside, the 3D and 4D.

      Paul finds it very hard to accept this, he is distracted by his present financial challenges.

      Isn't this (focus on 3dRef) what keeps us bound to the illusion?

    4. Paul, all energy is Light, and Light is the omnipresent energy that constitutes all life forms, all ideas, and all of every aspect of Conscious Being. it is the pure Light that is Love. It is the pure Light that constitutes Substance. It is the pure Light which differentiates Itself according to Intelligence as all that appears and all that is.

      Lot's here in this one paragraph.

      All energy is Light, it is a subset of Light. Light is ever present and constitutes every aspect of Being. Light is Love.

      That means every aspect of Being is Love - and all things are Love.

      Light differentiates itself, according to Intelligence, as all that is.

    1. Being is the Universal unfolding of It’s Self-perpetuating Action. Give up your attempts to grasp it, hold it, turn it over, and understand it by means of such examination. You must be willing to understand by virtue of Its Self-explanation. You must let go.

      Another description of Being and a suggestion to allow and understand it through its Self explanation.

    2. I understand completely, Paul. This is when you are experiencing the cohesiveness, the Oneness, of your Being. Your conscious experience should constantly be experienced from this Place. Go ahead and feel it and be consciously there. Notice that although you are relaxed, you are totally aware, and you are totally capable of movement and activity. But, you are quite aware that you are not in it and you are not investing your Self into any single experience. This is important.

      A description of the conscious experience of Being.

    1. Practice is truly a matter of not doing anything from a manipulative standpoint. It is truly a matter of relinquishing that finite concept of self, and going willingly within to that point where your Being is being consciously perceived as your Conscious Being.

      Practice described as dropping the finite concept of self - as not doing anything from a manipulative standpoint.

    2. Law, from a Universal standpoint, is constituted of Intelligence. It is the Mindful orderliness, the constituting of Harmony, of every aspect, and activity of Being. It is not a means of enforcement, but is, instead, the spontaneous but Absolute Principle according to which the functioning of Being occurs. Law is not a tool to use, but is the predisposing Nature of Intelligence to be inherently Principled.

      The description of Law that governs the order and harmony of every aspect of the activity of Being.

  21. Jul 2015
    1. Fig. 1 IAV requires the Ub-binding function of HDAC6 for capsid uncoating.

      In this figure the authors showed the results obtained when they investigated HDAC6 role in IAV entry.

      Panel A: The top part shows a cartoon of IAV entry that consists of multiple steps. The authors studied what step HDAC6 was critical during the virus host cell entry. Bottom part shows quantitative analysis graphs, each corresponding to the above step of IAV entry under investigation.

      Panel A (endocytosis): The authors measured the amount of HA-stained spots per cell in wild type MEFs (WT MEF) compared to HADC5 Knock-out MEFs (HDAC6 KO). The third bar represents WT MEFs that were treated with dynasore (Dyn) in order to stop the endocytosis process. Depletion of HDAC6 did not influence the endocytosis step.

      Panel A (HA-Acidification): In this step HDAC6 KO MEFS did not show any difference with respect to the wild type cells. It was concluded that HDAC6 does not influence this step of the virus infection.

      Panel A (Fusion): fusion of capsid to endosome membrane is not affected by the lack of HDAC6 in knock-out MEF cells as shown in graph.

      Panel A (Uncoating): Measuring the amount of cells with dispersed M1, the authors noticed that cells lacking HDAC6 dispersed less M1. This observation led to the conclusion that HDAC6 was fundamental for the uncoating process.

      Panel A (vRNP import): Indeed, As vRNP import represents the step following uncoating, HDAC6 KO MEFs showed less NP-positive nuclei because the previous uncoating step was reduced.

      In analyzing HA Acidification, Fusion, Uncoating and vRNP import, the authors used BafA1, which is a drug that is able to block uncoating, as a control for their experiment.

      Panel B is a graphical representation of the 2 deacetylase catalytic domains of HDAC6 and the zinc-finger ubiquitin binding domain that is close to the C-terminus of the enzyme.

      Panel C HDAC6 (WTr) (light gray bar) was a line of HDAC6 KO MEFs able to express again HDAC6. HDAC6 (HDm) (blue bar) was a line of HDAC6 KO MEFs expressing HDAC6 mutated in its deacetylase domain. HDAC6 (ZnFm) (purple bar) was a line of HDAC6 KO MEFs expressing HDAC6 with a mutation in its zinc-finger domain. The authors evaluated the effect of these mutations on the uncoating capacity of IAV. Depletion of deacetylase activity of HDAC6 did not influence the uncoating. Instead, loss of zinc-finger ubiquitin binding domain was detrimental for the uncoating.

      The two asterisks on top of the purple bar indicate that this result is statistically significant, that is a result that is caused by something other than mere random chance.

      Panel D: life in technicolor!!! These experiments were performed using the confocal microscopy technique. Fluorescent dye molecules bind to specific parts of the cell, so that only those parts are visualized. Fluorescent dyes are chemical compounds that re-emit light upon light excitation (light absorption).<br> The following video, created by Northwest Missouri State University, explains the basics of confocal microscopy. https://www.youtube.com/watch?v=jUAvneBhDcQ

      The authors observed that after 2.5 hours from infection, M1 is dispersed inside WT MEFs, indicating that uncoating has occurred. Instead, M1 is confined inside vacuoles when cells lack HDAC6 and the mutant cells in which HDAC6 lacks the Zinc-finger ubiquitin binding region, meaning that the uncoating hasn't occurred.

  22. May 2015
    1. A tool to improve reproducibility of data intensive science, recording progress as you work with tools such as R and Python.
  23. Feb 2015
    1. The goal of the DREAM Olfaction Prediction Challenge is to find models that can predict how a molecule smells from its physical and chemical features.
  24. Nov 2013
    1. For between two absolutely different spheres, as between subject and object, there is no causality, no correctness, and no expression; there is, at most, an aesthetic relation:

      Hm. Well, that's something, at least. Can we feel or sense or experience things beyond description with our sensory perception?