!- Question : Genetic Evolution

Does this mean that our predominantly cultural evolution threatens to freeze our genetic evolution? This is possible, since genetic evolution takes place on time scales that are orders of magnitudes larger than cultural evolution Unless theoretically proposed, it may have escaped detection for a long time

!- definition : Generation time - generation time of genetic transmission in range of 2 to 3 decades while for cultural transmission can vary from seconds to decades.

ReconfigBehSci. (2021, November 26). RT @mvankerkhove: Following the meeting of the @WHO TAG-VE today, WHO classifies B.1.1.529 as a variant of concern named Omicron. We call… [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1464302372100976650

loss of genetic variation threatens future food production systems.

Highly distinct populations with own genetic identity. Check out these papers for in depth info on Manomin genetic diversity - Kahler et al 2011, Kahler 2010, Kern and Kahler 2014

Explore this idea....

What does it look like quantitatively?

GeneName: DICER1 PMID (PubMed ID): 29762508 HGNCID: Unavailable Inheritance Pattern: Autosomal Dominant Disease Entity: cancer, rare genetic disorder, pleuroplumonary blastomas, cystic nephroma, rhabdomyosarcoma, multinodular goiter, thyroid cancer, overian Sertoli-Leydig cell tumors, and other meoplasias Mutations: Germline mutations or Somatic mutations Zygosity: Heterozygosity Variant: unregistered Family Information: Cystic nephromas has been reported in approximately 12% of children with pleuripulmonary blastomas or those with a family member with cystic nephroma. Patient with two DICER1 mutations and several of his family members shared these mutations. All members developed a least one type of tumor with differing origins. The patient was an 11-year old boy with a rare Hodgkin lymphoma with DICER1 in 2016. (c.5299delC and c.4616C>T).

Shelton, J. F., Shastri, A. J., Fletez-Brant, K., Stella Aslibekyan, & Auton, A. (2022). The UGT2A1/UGT2A2 locus is associated with COVID-19-related loss of smell or taste. Nature Genetics, 54(2), 121–124. https://doi.org/10.1038/s41588-021-00986-w

Davis, N., & correspondent, N. D. S. (2022, January 21). Covid reinfection: How likely are you to catch virus multiple times? The Guardian. https://www.theguardian.com/world/2022/jan/21/covid-reinfection-how-likely-are-you-to-catch-virus-multiple-times

Yonker, L. M., Boucau, J., Regan, J., Choudhary, M. C., Burns, M. D., Young, N., Farkas, E. J., Davis, J. P., Moschovis, P. P., Bernard Kinane, T., Fasano, A., Neilan, A. M., Li, J. Z., & Barczak, A. K. (2021). Virologic Features of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Children. The Journal of Infectious Diseases, 224(11), 1821–1829. https://doi.org/10.1093/infdis/jiab509

Sett, S., Ribeiro, C. dos S., Prat, C., Haringhuizen, G., Avšič, T., Batten, C., Beato, M. S., Bourhy, H., Caro, A. D., Charrel, R., Coutard, B., Drexler, J. F., Drosten, C., Fooks, A. R., Klempa, B., Koopmans, M., Klimkait, T., Günther, S., Manuguerra, J.-C., … Scholz, A. H. (2021). Access and benefit-sharing by the European Virus Archive in response to COVID-19. The Lancet Microbe, 0(0). https://doi.org/10.1016/S2666-5247(21)00211-1

Dance, A. (2021). The shifting sands of ‘gain-of-function’ research. Nature, 598(7882), 554–557. https://doi.org/10.1038/d41586-021-02903-x

Rono, E. K. (2021). Covid-19 genomic analysis reveals clusters of emerging sublineages within the delta variant [Preprint]. Genomics. https://doi.org/10.1101/2021.10.08.463334

Zimmer, C., Corum, J., & Wee, S.-L. (2020, June 10). Coronavirus Vaccine Tracker. The New York Times. https://www.nytimes.com/interactive/2020/science/coronavirus-vaccine-tracker.html

Warmerdam, R., Wiersma, H. H., Lanting, P., Dijkema, M. X. L., Vonk, J. M., Boezen, M. H. M., Deelen, P., & Franke, L. (2021). Increased genetic contribution to wellbeing during the COVID-19 pandemic. PsyArXiv. https://doi.org/10.31234/osf.io/uksxt

the Guardian. ‘How a String of Failures by the British Government Helped Covid-19 to Mutate | Anthony Costello’, 22 December 2020. http://www.theguardian.com/commentisfree/2020/dec/22/uk-government-blamed-covid-19-mutation-occur.

Vries, L. de, Weijer, M. van de, Pelt, D., Ligthart, L., Willemsen, G., Boomsma, D., Geus, E. de, & Bartels, M. (2021). Individual differences in the effect of the COVID-19 pandemic on optimism and meaning in life. PsyArXiv. https://doi.org/10.31234/osf.io/b2ge6

More Covid Vaccine Choices Mean New Equity Challenges. (n.d.). Wired. Retrieved 11 February 2021, from https://www.wired.com/story/more-covid-vaccine-choices-mean-new-equity-challenges/

Robert, A., Funk, S., & Kucharski, A. J. (2019). The measles crisis in Europe—The need for a joined-up approach. The Lancet, 393(10185), 2033. https://doi.org/10.1016/S0140-6736(19)31039-6

Lawton. G. (2020) Coronavirus family tree reveals the virus is hardly mutating. New Scientist. Retrieved from: https://www.newscientist.com/article/2254387-coronavirus-family-tree-reveals-the-virus-is-hardly-mutating/?utm_medium=social&utm_campaign=echobox&utm_source=Twitter#Echobox=1600082893

The process of putting genetic material and encapsulating it with a coat of proteins.

This involves taking a DNA sample from a crime scene to compare with a sample of DNA from a suspect via their fingerprint.

This states that chromosomes drive the genetic heredity of living organisms. Chromosome behavior takes part in segregation, assortment, and sometimes linkage.

Blokland, I. V. van, Lanting, P., Ori, A. P., Vonk, J. M., Warmerdam, R. C., Herkert, J. C., Boulogne, F., Claringbould, A., Lopera-Maya, E. A., Bartels, M., Hottenga, J.-J., Ganna, A., Karjalainen, J., Study, L. C.-19 cohort, Initiative, T. C.-19 H. G., Hayward, C., Fawns-Ritchie, C., Campbell, A., Porteous, D., … Franke, L. H. (2020). Using symptom-based case predictions to identify host genetic factors that contribute to COVID-19 susceptibility. MedRxiv, 2020.08.21.20177246. https://doi.org/10.1101/2020.08.21.20177246

Genetic manipulation has been a running gag/ideal within the furry community for as long as it has existed. The idea of transformation by any means possible is appealing, and these sorts of genetic components would go a long way in establishing that sense of identity.

For the article to name this fallacy and thoroughly debunk it, see Edwards, A. W. F. (2003). Human genetic diversity: Lewontin's fallacy. BioEssays, 25, 798-801. doi:10.1002/bies.10315

I can't believe we got away with putting this image into a scholarly article.

There's a difference between selective breeding and altering via genetic engineering. I believe that genetic modification falls into the second category, always.

The Long Now Foundation and its views open up a whole chasm of moral, ethical, and legal questions with this 'DeExtinction Movement'. How is genetically engineering endangered species a form of 'genetic rescue'? These species are dying out because of man and man's actions, which is a terrible reflection of the worst part of human nature, but it does not give us the right to clone nature and 'whitewash' all that we have done before. Just because we may have the capacity to do so, does not mean we should. We cannot simply decide that extinction is fine because we can create genetically engineered species in the future to 'make up' for our mistakes. How are we expected to learn from our mistakes if we can simply rewind and start again?

Transhumanists are at war with the bioconservatives. This just sounds like a William Gibson sci-fi novel. We live in amazing times. That said, global bans on technology and science never work; they just really mess things up. Regardless of what the bioconservatives think, there are cultures that will embrace these technologies (and already do). Historically, and possibly without exception, countries that ban or hobble new technologies eventually regret it because at least some of their neighbors will not follow suit. Further, by outright turning their back on the technology, they lose any voice they might have had in determining how it will be employed.

genetic vs. environmental influences on the formation of conscience