BCPs assemble into a variety of different morphologies that are influenced by polymer molecular weights and block ratios, with further control possible through the manipulation of environmental conditions such as temperature, solvent, and concentration

solution

Because dynein inhibition alone did not inhibit IAV uncoating completely, we investigated a possible additional role for the actomyosin system

we noticed that another histone deacetylase, HDAC6, was also required for infection

With the risk of an influenza pandemic growing, it is increasingly important to understand virus-host interactions in detail and to develop new antiviral strategies (1).

This course introduces students to the basic knowledge representation, problem solving, and learning methods of artificial intelligence.

The motion of probe particles trackedinside cells has been classified as subdiffusive,diffusive, or superdiffusive. Such classifications,however, obscure the distinction between ther-mally driven and nonequilibrium fluctuationsand are inadequate to identify intracellular ma-terial properties

Connected learning boils down to risk taking in the end. To quote colleague Jade Davis from her recent DML blog post, “I think the biggest risk in connected learning is Not Trying.”

While I’d struggle to tell you how I learn best, there is one question that I’d always be able to answer enthusiastically: What would you like to learn next? Right now I’m learning JavaScript and have plans to give Spanish another go. I should probably pick up those guitar lessons again soon as well. Thankfully we live in a time when it’s trivially easy to gain access to resources and to learning activities. The problem is finding out the ones that work best for you. Perhaps that’s why we carry around in our pockets devices that can access pretty much the sum total of human knowledge yet use them to LOL at amusing pictures of cats. What are the barriers here? I’d suggest there are three main ones: 1 Curriculum - the series of activities that build towards a learning goal 2 Credentials - the ability to show what you know 3 Community - the cohort of peers you feel you are part of, along with access to ‘experts’

The “connected learning” term seems to derive from this infographic on connected learning and the folk who developed it. Their “What is Connected Learning” provides more of an overview, including principles (see the following table) and a research synthesis report.

That power is unleashed when teachers see the portfolio process as dependent upon the clarity of goals for student performance through their work in the liberal arts and professional education curriculum; when they attend to the quality of the assignments, projects and assessments that they provide for their students; and when they take the responsibility for teaching students the process of reflection and self assessment.

Enter the Daily Mail website, MailOnline, and CNN online. These sites display news stories with the main points of the story displayed as bullet points that are written independently of the text. “Of key importance is that these summary points are abstractive and do not simply copy sentences from the documents,” say Hermann and co.

expanded learning schedules

effective democratic participation

collaboration

the Common Core standards are strongly aligned with deeper learning—and represent an especially promising leverage point for the Program to help advance its goals . 9

portfolios,

The new Common Core State Standards are an enormous step forward toward the goal of preparing all students for the future: across forty-five states, schools are now required to teach skills like critical thinking and effective communication alongside core academic content.

When learning is personalized,

Steven Wheeler’s presentation below reviews related ideas contextualizing the modern learning climate. The gist? Rapid technology change has produced critical new pathways for both formal and informal learning.

Rhizomatic Learning Is A Metaphor For How We Learn

colour as an object-centred

‘how does it work?

riting rhizomatically; understanding texts as rhizomatic; and analyzing the rhizomatic linkages between texts and the talk of the research participants.

We are in desperate need of new concepts, Deleuzian or otherwise, in this new educational environment that privileges a single positivist research model with its transcendent rationality and objectivity and accompanying concepts such as randomization, replicability, generalizability, bias, and so forth—one that has marginalized subjugated knowledges and done material harm at all levels of education, and one that many educators have resisted with some success for the last fifty years

Todd May (1996) explains that Deleuze’s ontology is ‘built upon the not-so-controversial idea that how we conceive the world is relevant to how we live in it.’

Now you might ask what this discussion of subjectivity in Deleuze has to do with education and science, and I would respond—everything, everything. All of education and science is grounded in certain theories of the subject; and if the subject changes, everything else must as well

Rather than asking what a concept means, you will find yourself Deleuzian Concepts for Education: The subject undone 285 © 2004 Philosophy of Education Society of Australasia asking, ‘Does it work? what new thoughts does it make possible to think? what new emotions does it make possible to feel? what new sensations and perceptions does it open in the body?’ (Massumi, 1992, p. 8). You soon give up worrying about what Deleuze might have intended and use him in your own work ‘to free life from where it’s trapped, to trace lines of flight’ (Deleuze, 1990/1995, p. 141) into a different wa y of being in the world

permission to give up the pretense of signifying and ‘making meaning’ in the old way

Now you might ask what this discussion of subjectivity in Deleuze has to do with education and science, and I would respond—everything, everything. All of education and science is grounded in certain theories of the subject; and if the subject changes, everything else must as well.

haecceity

One form of resistance to the scientism produced by the old values of government functionaries involves accomplishing scholarship that critiques those values and introduces concepts that upset the established order. This essay participates in that resistance, illustrating how Deleuzian concepts keep the field of play open, becoming, rhizomatic, with science springing up everywhere, unrecognizable according to the old rules, coming and going in the middle, ‘where things pick up speed’ (Deleuze & Guattari, 1980/1987, p. 25).

We are in desperate need of new concepts, Deleuzian or otherwise, in this new educational environment that privileges a single positivist research model with its transcendent rationality and objectivity and accompanying concepts such as randomization, replicability, generalizability, bias, and so forth—one that has marginalized subjugated knowledges and done material harm at all levels of education, and one that many educators have resisted with some success for the last fifty years.

Deleuze's ontology is ‘built upon the not-so-controversial idea that how we conceive the world is relevant to how we live in it

The “dark” side of Rhizo14 related to many of the gaps in MOOC research that have been noted by other researchers and referenced in the review of literature. Rhizo14 participants for whom the experience was less than positive felt isolated. They felt unable to make meaningful connections despite in some cases being experienced “MOOCers.” One viewed the emphasis on community as an unnecessary pressure, which led to artificial effects, exclusion and limited learning. Another viewed the community as “ disjointed networks of pre-established subgroups. ” Another described the community as having a “ dark edge .” These participants felt that there was a lack of appropriate facilitation, and that there were inappropriate exhibitions of power and politics in the course. Some felt that the course was based on weak philosophical foundations and that the rhizome is an empty signifier. Some questioned the lack of content in the course and felt that it lacked depth and theoretical discussion. For these participants the rhizome is “ A pernicious, pervasive weed, rooted in a lot of dirt and “SH***””; “ . . .a ‘thug’ and can be very badly behaved”; “Part of one big family/ plant—joined at the hip”; “Clones of the “same damn plan t.” One respondent wrote “I knew before that the arborescent paradigm was a problem. The rhizome is a contrasting alternative, but I learned in the course that this alternative has a lot of connotations with ugly and weed-like characteristics which are not necessary for every complex or even chaotic network” (survey respondent)

as researchers and policy makers look to build more sustainable futures, they would be wise to design creative ways to support parents even as they pour more resources into supporting students. We instinctively understand that our public institutions (i.e., schools), policy initiatives, and the spread of media technologies must be a valuable resource for students. But, how can these institutions, policies and technologies become an asset for parents?

“Making creates evidence of learning.” The thing you make—whether it be a robot, rocket, or blinking LED—is evidence that you did something, and there is also an entire process behind making that can be talked about and shared with others. How did you make it? Why? Where did you get the parts? Making is not just about explaining the technical process; it’s also about the communication about what you’ve done.

Teaching has been reduced to the written equivalent of TV news sound bites in pan, because so many groups lobby hard for inclusion of their p et ideas Moreover, much of what they wish to be taught i s n ow taught; the problem is that it isn't learned and can't easily be, given the inert and glib quality of the text. Con tent is reducible to sound bites only when curricular lobbyists (and an alarming number of educators) be lieve that learning occurs merely by hearing or seeing the "truth." The problem of student ignorance is thus really about a dult i gnorance as to how thoughtful and long-lasting under standing is achieved

The view that everything of importance can be thoughtfully learned by the 12th grade notice I did not say "taught" is a delusion

Jean Lave’s theory of situated cogni-tion focuses on learning as enculturation into a practice, often through the process of “legitimate peripheral participation” in a laboratory, studio, or workplace set-ting. Although this term is often thought of as equivalent to apprenticeship learn-ing, it is a more general concept. In an apprenticeship, the student is there to learn a practice under a master who, if he or she is good, has carefully meted out a set of increasingly challenging activities for the student to perform. In peripheral participation the student is engaged in real work, fully participating in the tech-nical and social interchanges. He or she is able not only to learn to do the job, but also to pick up, as though through osmo-sis, the sensibilities, beliefs, and idiosyn-crasies of the particular community of practice. Learning happens seamlessly as part of an enculturation process as the learner moves from the periphery to a more central position in the community.

Equally important is our social-emo - tional development in learning how to use our feelings—our emotional relations to others and our emotional reactions to events—for constructive purpose

ndividual learners and neglect group-level learning and project-level or organization-level learning

But as a society, we are not concerned with novices. Eventually they will quit being novices, without our having to do anything about it. The important question is what they will become. Will they become experts in their lines of work or will they swell the ranks of incompetent or mediocre functionaries?

To develop this exhibition Life recognised that people construct knowledge for themselves, rather than passively absorb what’s fed to them, and they learn to learn as they learn.

Logistic regression, also called a logit model, is used to model dichotomous outcome variables. In the logit model the log odds of the outcome is modeled as a linear combination of the predictor variables.

“do they care?”.

There are many ways to start... learn.perl.orgexternal link A brief introductionexternal link Free online Perl books Join your local community Books and More

Git Basics So, what is Git in a nutshell?

Full Text Beginning Perl Modern Perl Impatient Perl Extreme Perl Embedding Perl in HTML with Mason Picking Up Perl Perl 5 Internals Practical Mod Perl Perl & LWP

Lisp Quickstart

The goal of this site is to provide a set of materials in support of my Python for Informatics: Exploring Information book to allow you to learn Python on your own. This page serves as an outline of the materials to support the textbook.

This deck contains all must-have basic Esperanto rootwords as suggested by the editorial team of the magazine Kontakto.

The notion behind it was that one could decompose, e.g., Applicative into an instance of the Pointed typeclass and an instance of the Apply typeclass (giving apply :: f (a -> b) -> f a -> f b) and an instance of Pointed, such that the two interact properly.

A day of lost work pursuing the wrong solution is something that is acceptable from a learning point of view.

The hard part is teaching the consequences of each choice.

permalink

ut what is better than wholesome sweetness or sweet wholesomeness? For the sweeter we try to make such things, the easier it is to make their wholesomeness serviceable. And so there are writers of the Church who have expounded the Holy Scriptures, not only with wisdom, but with eloquence as well; and there is not more time for the reading of these than is sufficient for those who are studious and at leisure to exhaust them.

But only by those who can learn them any one who cannot learn this art quickly can never thoroughly learn it

And, therefore, as infants cannot learn to speak except by learning words and phrases from those who do speak, why should not men become eloquent without being taught any art of speech, simply by reading and learning the speeches of eloquent men, and by imitating them as far as they can?

For men of quick intellect and glowing temperament find it easier to become eloquent by reading and listening to eloquent speakers than by following rules for eloquence.

That mere boys should sit mixed with young men, I do not approve

That mere boys should sit mixed with young men, I do not approve; for though such a man as ought to preside over their studies and conduct may keep even the eldest of his pupils under control, yet the more tender ought to be separate from the more mature, and they should all be kept free, not merely from the guilt of licentiousness, but even from the suspicion of it

Of these professors the morals must first be ascertained, a point of which I proceed to treat in this part of my work, not because I do not think that the same examination is to be made, and with the utmost care, in regard also to other teachers (as indeed I have shown in the preceding book), but because the very age of the pupils makes attention to the matter still more necessary. 3. For boys are consigned to these professors when almost grown up and continue their studies under them even after they are become men. Greater care must in consequence be adopted with regard to them in order that the purity of the master may secure their more tender years from corruption and that his authority deter their bolder age from licentiousness. 4. Nor is it enough that he give, in himself, an example of the strictest morality, unless he regulate also, by severity of discipline, the conduct of those who come to receive his instructions.

We are by nature most tenacious of what we have imbibed in our infant years

As birds are born to fly, horses to run, and wild beasts to show fierceness, so to us peculiarly belong activity and sagacity of understanding; hence the origin of the mind is thought to be from heaven. 2. But dull and unteachable persons are no more produced in the course of nature than are persons marked by monstrosity and deformities, such are certainly but few.

his may seem a trifling matter to mention, but when it is neglected, many faults of pronunciation, unless they are removed in the years of youth, are fixed by incorrigible ill habit for the rest of life.

I do not disapprove, however, the practice, which is well known, of giving children, for the sake of stimulating them to learn, ivory figures of letters to play with, or whatever else can be invented, in which that infantine age may take delight, and which may be pleasing to handle, look at, or name.

This advancement, extended through each year, is a profit on the whole, and whatever is gained in infancy is an acquisition to youth. The same rule should be prescribed as to the following years, so that what every boy has to learn, he may not be too late in beginning to learn. Let us not then lose even the earliest period of life, and so much the less, as the elements of learning depend on the memory alone, which not only exists in children, but is at that time of life even most tenacious.

Let reading, therefore, be at first sure, then continuous, and for a long time slow, until, by exercise, a correct quickness is gained.

The study of Latin ought, therefore, to follow at no long interval, and soon after to keep pace with the Greek; thus it will happen that when we have begun to attend to both tongues with equal care, neither will impede the other.

The best of rules, therefore, are to be laid down, and if any one shall refuse to observe them, the fault will lie not in the method, but in the man.

Nor is their misconduct less prejudicial to the manners of their pupils;

Since they disdain to yield to those who are skilled in teaching and, growing imperious, and sometimes fierce, in a certain right, as it were, of exercising their authority (with which that sort of men are generally puffed up), they teach only their own folly.

Of paedagogi this further may be said, that they should either be men of acknowledged learning, which I should wish to be the first object, or that they should be conscious of their want of learning; for none are more pernicious than those who, having gone some little beyond the first elements, clothe themselves in a mistaken persuasion of their own knowledge.

Before all things, let the talk of the child's nurses not be ungrammatical.

For it will be necessary, above all things, to take care lest the child should conceive a dislike to the application which he cannot yet love, and continue to dread the bitterness which he has once tasted, even beyond the years of infancy

I prefer that a boy should begin with the Greek language, because he will acquire the Latin in general use, even though we tried to prevent him, and because, at the same time, he ought first to be instructed in Greek learning, from which ours is derived

If, however, it should not be the good fortune of children to have such nurses as I should wish, let them at least have one attentive paedagogus, not unskilled in language, who, if anything is spoken incorrectly by the nurse in the presence of his pupil, may at once correct it and not let it settle in his mind. But let it be understood that what I prescribed at first is the right course, and this only a remedy

33

To beginners should be given matter designed, as it were, beforehand in proportion to the abilities of each. But when they shall appear to have formed themselves sufficiently on their model, a few brief directions may be given them, following which, they may advance by their own strength without any support. 6. It is proper that they should sometimes be left to themselves, lest, from the bad habit of being always led by the efforts of others, they should lose all capacity of attempting and producing anything for themselves. But when they seem to judge pretty accurately of what ought to be said, the labor of the teacher is almost at an end, though should they still commit errors, they must be again put under a guide. 7.

On such subjects did the ancients, for the most part, exercise the faculty of eloquence, borrowing their mode of argument, however, from the logicians. To speak on fictitious cases, in imitation of pleadings in the forum or in public councils, is generally allowed to have become a practice among the Greeks, about the time of Demetrius Phalereus.

We make it also a subject of inquiry when a boy may be considered ripe for learning what rhetoric teaches. In which inquiry it is not to be considered of what age a boy is, but what progress he has already made in his studies. That I may not make a long discussion, I think that the question when a boy ought to be sent to the teacher of rhetoric is best decided by the answer, when he shall be qualified.

For minds, before they are hardened are more ready to learn, as is proved by the fact that children, within two years after they can fairly pronounce words, speak almost the whole language, though no one incites them to learn; but for how many years does the Latin tongue resist the efforts of our purchased slaves! You may well understand, if you attempt to teach a grown up person to read, that those who do everything in their own art with excellence are not without reason called παιδομαθεῖς (paidomatheis), that is, "instructed from boyhood." 10. The temper of boys is better able to bear labor than that of men, for as neither the falls of children, with which they are so often thrown on the ground, nor their crawling on hands and knees, nor, soon after, constant play and running all day hither and thither, inconvenience their bodies so much as those of adults, because they are of little weight and no burden to themselves, so their minds likewise, I conceive, suffer less from fatigue, because they exert themselves with less effort and do not apply to study by putting any force upon themselves, but merely yield themselves to others to be formed. 11. Moreover, in addition to the other pliancy of that age, they follow their teachers, as it were, with greater confidence and do not set themselves to measure what they have already done. Consideration about labor is as yet unknown to them, and as we ourselves have frequently experienced, toil has less effect upon the powers than thought.

The teacher will he cautious, likewise, that concluding syllables be not lost; that his pupil's speech be all of a similar character; that whenever he has to raise his voice, the effort may be that of his lungs, and not of his head; and that his gesture may be suited to his voice, and his looks to his gesture. 9

SOME TIME is also to be devoted to the actor, but only so far as the future orator requires the art of delivery, for I do not wish the boy whom I educate for this pursuit either to be broken to the shrillness of a woman's voice or to repeat the tremulous tones of an old man's. 2. Neither let him imitate the vices of the drunkard nor adapt himself to the baseness of the slave; nor let him learn to display the feelings of love, or avarice, or fear: acquirements which are not at all necessary to the orator and which corrupt the mind, especially while it is yet tender and uninformed in early youth, for frequent imitation settles into habit.

BY speakers, as well as writers, there are certain rules to be observed. Language is based on reason, antiquity, authority, custom. It is analogy, and sometimes etymology, that affords the chief support to reason. A certain majesty, and, if I may so express myself, religion, graces the antique.

At present, the negligence of paedagogi seems to be made amends for in such a way that boys are not obliged to do what is right, but are punished whenever they have not done it. Besides, after you have coerced a boy with stripes, how will you treat him when he becomes a young man, to whom such terror cannot be held out, and by whom more difficult studies must be pursued? 16. Add to these considerations that many things unpleasant to be mentioned, and likely afterwards to cause shame, often happen to boys while being whipped, under the influence of pain or fear. Such shame enervates and depresses the mind, and makes them shun people's sight and feel a constant uneasiness. 17. If, moreover, there has been too little care in choosing governors and tutors of reputable character, I am ashamed to say how scandalously unworthy men may abuse their privilege of punishing, and what opportunity also the terror of the unhappy children may sometimes accord to others. I will not dwell upon this point; what is already understood is more than enough. It will be sufficient, therefore, to intimate that no man should be allowed too much authority over an age so weak and so unable to resist ill treatment.

Would not he seem to be affected with something like madness? There would be no eloquence in the world if we were to speak only with one person at a time.

But supposing that either interest, or friendship, or money, should secure to any parent a domestic tutor of the highest learning, and in every respect unrivalled, will he, however, spend the whole day on one pupil? Or can the application of any pupil be so constant as not to be sometimes wearied, like the sight of the eyes, by continued direction to one object, especially as study requires the far greater portion of time to be solitary.

People think that morals are corrupted in schools; indeed they are at times corrupted, but such may be the case even at home.

I AM aware that it is also a question whether nature or learning contributes most to oratory. This inquiry, however, has no concern with the subject of my work, for a perfect orator can be formed only with the aid of bot

would exercise the pupils under his care in the reading of history and even still more in that of speeches,

while the teachers of philosophy impart all the forms of discourse in which the mind expresses itself. Then, when they have made them familiar and thoroughly conversant with these lessons, they set them at exercises, habituate them to work, and require them to combine in practice the particular things which they have learned, in order that they may grasp them more firmly and bring their theories into closer touch with the occasions for applying them