30 Matching Annotations
  1. Aug 2022
    1. Pozzetto, B., Legros, V., Djebali, S., Barateau, V., Guibert, N., Villard, M., Peyrot, L., Allatif, O., Fassier, J.-B., Massardier-Pilonchéry, A., Brengel-Pesce, K., Yaugel-Novoa, M., Denolly, S., Boson, B., Bourlet, T., Bal, A., Valette, M., Andrieu, T., Lina, B., … Trouillet-Assant, S. (2021). Immunogenicity and efficacy of heterologous ChadOx1/BNT162b2 vaccination. Nature, 1–9. https://doi.org/10.1038/s41586-021-04120-y

    1. Lauring, A. S., Tenforde, M. W., Chappell, J. D., Gaglani, M., Ginde, A. A., McNeal, T., Ghamande, S., Douin, D. J., Talbot, H. K., Casey, J. D., Mohr, N. M., Zepeski, A., Shapiro, N. I., Gibbs, K. W., Files, D. C., Hager, D. N., Shehu, A., Prekker, M. E., Erickson, H. L., … Self, W. H. (2022). Clinical severity of, and effectiveness of mRNA vaccines against, covid-19 from omicron, delta, and alpha SARS-CoV-2 variants in the United States: Prospective observational study. BMJ, 376, e069761. https://doi.org/10.1136/bmj-2021-069761

  2. Apr 2022
  3. Dec 2021
    1. A sharp rise in reported active volcanoes immediately post-WW II was followed by another steep increase in the early 1950s that has no obvious relationship to historic events.

      'No obvious relationship to historic events' is blatantly inaccurate here. The US military was active in the Pacific for the entirety of this time frame reestablishing the power in the Pacific US colonies. It naturally would follow that volcanic activity would be reported at higher rates as military vessels were combing the area.

  4. Sep 2021
    1. Haber, N. A., Wieten, S. E., Rohrer, J. M., Arah, O. A., Tennant, P. W. G., Stuart, E. A., Murray, E. J., Pilleron, S., Lam, S. T., Riederer, E., Howcutt, S. J., Simmons, A. E., Leyrat, C., Schoenegger, P., Booman, A., Dufour, M.-S. K., O’Donoghue, A. L., Baglini, R., Do, S., … Fox, M. P. (2021). Causal and Associational Linking Language From Observational Research and Health Evaluation Literature in Practice: A systematic language evaluation [Preprint]. Epidemiology. https://doi.org/10.1101/2021.08.25.21262631

  5. Aug 2021
  6. Jul 2021
    1. These observations were made with the naked eye and with the help of some simple instruments as the gnomon. The Babylonians, in particular, were rather advanced observers. Archeologists have found an abundance of cuneiform texts on astronomical observations. In contrast, there exists only one report of an observation made by Anaximander, which concerns the date on which the Pleiades set in the morning. This is no coincidence, for Anaximander’s merits do not lie in the field of observational astronomy, unlike the Babylonians and the Egyptians, but in that of speculative astronomy. We may discern three of his astronomical speculations: (1) that the celestial bodies make full circles and pass also beneath the earth, (2) that the earth floats free and unsupported in space, and (3) that the celestial bodies lie behind one another. Notwithstanding their rather primitive outlook, these three propositions, which make up the core of Anaximander’s astronomy, meant a tremendous jump forward and constitute the origin of our Western concept of the universe.

      Anaximander practiced speculative astronomy instead of just observational astronomy and in so doing, he dramatically changed the cosmological outlook of Western culture.

  7. May 2021
  8. Mar 2021
  9. Feb 2021
  10. Sep 2020
    1. Ip, A., Ahn, J., Zhou, Y., Goy, A. H., Hansen, E., Pecora, A. L., Sinclaire, B. A., Bednarz, U., Marafelias, M., Mathura, S., Sawczuk, I. S., Underwood, J. P., Walker, D. M., Prasad, R., Sweeney, R. L., Ponce, M. G., LaCapra, S., Cunningham, F. J., Calise, A. G., … Goldberg, S. L. (2020). Hydroxychloroquine in the treatment of outpatients with mildly symptomatic COVID-19: A multi-center observational study. MedRxiv, 2020.08.20.20178772. https://doi.org/10.1101/2020.08.20.20178772

  11. Aug 2020
  12. May 2020
    1. Hippocampal size of nonusers reflects a direct relationship to memory function; the smaller the hippocampus, the poorer the memory function. Individuals who use marijuana and tobacco show an inverse relationship, i.e., the smaller the hippocampus size, the greater memory the function. Furthermore the number of nicotine cigarettes smoked per day in the marijuana and nicotine using group appears to be related to the severity of hippocampal shrinkage. The greater the number of cigarettes smoked per day, the smaller the hippocampal volume and the greater the memory performance. There were no significant associations between hippocampal size and memory performance in individuals who only use tobacco or only use marijuana.

      They mention abstainers below. It appears that they are saying that there is memory improvement compared to complete non-smokers. Will need to check actual study. Note that my interest in nicotine is confounded by the use of tobacco.

      Edit: eyeballing the graphs, it appears that the tobacco group did the best, while the marijuana plus tobacco group did the worst. Given the small sample size and high variability, these are not statistically significant. Nonetheless, that suggests that marijuana never benefits memory. Edit: eyeballing the graphs, it appears the tobacco group did the best, while the marijuana plus tobacco group performed worst. Given the small sample size and high variability, these results are not statistically significant. Nonetheless, it suggests that marijuana is never a benefit to memory.