A 2 fold molar excess of peptide was added to the protein prior to crystallization (RGAFQNLFQSV).

tunnel splitting

Related concepts in other fields are: In natural language, the coordinating conjunction "and". In programming languages, the short-circuit and control structure. In set theory, intersection. In predicate logic, universal quantification.

The context item

ssh-add <(echo "$PRIVATE_KEY")

mv "$DEPLOY_KEY_PRIVATE" ~/.ssh/id_rsa

deployer-token

machines tend to be designed for the lowest possible risk and the least casualties

1. Disabling concrete extension update. That's what I wanted! You can do this by editing the extensions manifest json-file on Windows: C:\Users\<USERNAME>\AppData\Local\Google\Chrome\User Data\Default\Extensions\<EXTENSION-ID>\<VERSION>\manifest.json (find out the extensions ID by enabling developer mode in the extension settings page) on Ubuntu for Chromium: ${HOME}/.config/chromium/Default/Preferences In this file set "update_url" property to something invalid like "https://localhost" for example. For now according to given url updating of that extension is simply impossible.

infinite time

shouldn't a MR be treated as an unit of work, independent from master?

If you update your pages and push to github, people revisiting the pages who have already got cached copies will not get the new pages without actually cleaning their browser cache. How can a script running in a page determine that it is stale and force an update?

The consent provided by the user is saved in some cookies within the host page’s domain. By verifying the presence or the absence of these cookies you can determine whether the user has given their consent or not.

Protein:lipid~3:1

Make it clear that signing up is optional. Consent must be “freely given”; you may not coerce users into joining your mailing list or make it appear as if joining the list is mandatory. For this reason, you must make it clear that signing up is optional. This is especially relevant in cases where you offer free white-papers (or e-books) for download. While the user’s email address is required for the delivery of the service, signing up for your newsletter is not. In such a case, you must not make it appear as if signing-up to the newsletter list mandatory and must make it clear that it is optional.

Ideally you should really test these parameters (by comparing to ab initio calculations for example) to ensure they are reasonable

C, N, O, S, P, H, F, Cl, Br and I

Regular Expression Functions There are three regular-expression functions that operate on strings: matches() tests if a regular expression matches a string. replace() uses regular expressions to replace portions of a string. tokenize() returns a sequence of strings formed by breaking a supplied input string at any separator that matches a given regular expression. Example:   

What’s the difference between xsl:value-of, xsl:copy-of, and xsl:sequence? xsl:value-of always creates a text node. xsl:copy-of always creates a copy. xsl:sequence returns the nodes selected, subject possibly to atomization. Sequences can be extended with xsl:sequence.

<xsl:variable name="date" select="xs:date('2003-11-20')"/>

Types XSLT 2.0 allows you to declare: The type of variables. The return type of templates. The type of sequences (constructed with xsl:sequence) The return type of (user-declared) functions. Both the type and required type of parameters.

 <xsl:sequence select="1 to 16"/>

<xsl:for-each select="1 to 32">  <!-- Do something useful here --></xsl:for-each>

The new as attribute defines the data type of the variable, and the asterisk (xs:integer*) means that the sequence contains zero or more integers

One of the major new concepts in XPath 2.0 and XSLT 2.0 is that everything is a sequence.

relax ligand-receptor complexeswithout causing major alterations of their originalgeometry, or to perform a torsional scan on a selecteddihedral while relaxing the rest of the molecule.

MONN contains a pairwise interaction prediction module, which can capture the non-covalent interactions between atoms of a compound and residues of a protein with extra supervision from the labels extracted from available high-quality 3D compound-protein complex structures

available

A company runs a memory-intensive analytics application using on-demand Amazon EC2 C5 compute optimized instance. The application is used continuously and application demand doubles during working hours. The application currently scales based on CPU usage. When scaling in occurs, a lifecycle hook is used because the instance requires 4 minutes to clean the application state before terminating.Because users reported poor performance during working hours, scheduled scaling actions were implemented so additional instances would be added during working hours. The Solutions Architect has been asked to reduce the cost of the application.Which solution is MOST cost-effective?

Mixed the plate thoroughly and incubated for one hour at room temperature. Then 5 μL development solution was added to each well and the plate was incubated for 1h at room temperature;

Structure-Based Design

6NTS

What is a Function Expression?A JavaScript function can also be defined using an expression.A function expression can be stored in a variable:var x = function (a, b) {return a * b};After a function expression has been stored in a variable, the variable can be used as a function. Functions stored in variables do not need function names. They are always invoked (called) using the variable name.

Writing an async function is quite simple. You just need to add the async keyword prior to function:

Our Promise can have one of three states:

Using objects as keys is one of most notable and important Map features.

Map is a collection of keyed data items, just like an Object. But the main difference is that Map allows keys of any type.

he basic syntax is: let promise = fetch(url, [options])

Webpack is a most have to compile a complete JavaScript project.

linter

This tool accepts both a configuration file and line parameters.

Here are the possible ways to make an API call:XMLHttpRequestfetchAxiosjQuery

A poised fragment library enables rapid syntheticexpansion yielding thefirst reported inhibitors ofPHIP(2), an atypical bromodomain

Most pages aren’t very dynamic, and therefore won’t have any orphans. In these cases, the orphans tab will not appear.

document.addEventListener(event, function, useCapture)

It should be 48x48 pixels.

It is an unordered set of name/value pairs.

Square brackets hold arrays and values are separated by ,(comma).

JSON syntax is basically considered as a subset of JavaScript syntax;

name/value pairs.

Extensions for Firefox are built using the WebExtensions APIs, a cross-browser system for developing extensions.

The most interesting key here is content_scripts, which tells Firefox to load a script into

description is optional, but recommended: it's displayed in the Add-ons Manager. icons is optional, but recommended: it allows you to specify an icon for the extension, that will be shown in the Add-ons Manager.

The first three keys: manifest_version, name, and version, are mandatory and contain basic metadata for the extension.

Never use eval()! eval() is a dangerous function, which executes the code it's passed with the privileges of the caller.

The popup is specified as an HTML file, which can include CSS and JavaScript files, as a normal web page does.

Popups resize automatically to fit their content.

There are two ways to specify a browser action: with or without a popup

The only mandatory key is default_icon

Specifying the browser action

ommonly referred to as a browser action, this user interface option is a button added to the browser toolbar. Users click the button to interact with your extension.

An extension is a simple collection of files that modify the browser’s appearance and behavior.

Your client’s CloudWatch Logs configuration receives logs and data from on-premises monitoring systems and agents installed in operating systems. A new team wants to use CloudWatch to also monitor Amazon EC2 instance performance and state changes of EC2 instances, such as instance creation, instance power-off, and instance termination. This solution should also be able to notify the team of any state changes for troubleshooting.

Chrome first sends an encrypted, 3-byte hash of your username to Google, where it is compared to Google's list of compromised usernames. If there's a match, your local computer is sent a database of every potentially matching username and password in the bad credentials list

Over the years, many people have said "well, the data is public anyway by virtue of it having been breached, what's the problem if you now store the password in your system?" Here's the philosophical problem I have with that:

Override Changes

Changes are still received so the folder may become “out of sync”, but no changes will be applied.

We do notknow how the WIN site tethers WDR5 to chromatin.

myc-TEAD1

cking pose for compound 3.1.

We did not use the YAP peptides containing residues in interface1 because it has been shown that interface 1 is dispensable forYAP binding

YAP peptide

The central pocket of TEADs has an excellent druggabilityscore

What data is being collected? How is that data being collected?

For which specific purposes are the data collected? Analytics? Email Marketing?

What is the Legal basis for the collection?

Using our privacy policy software implies having a third party integrate into your site. This post explains what kind of data is and is not tracked by iubenda.

In the absence of insulin, the entry of glucose into skeletal, cardiac, and smooth muscle and other tissues is decreased (Figure 24–8). Glucose uptake by the liver is also reduced, but the effect is indirect. Intestinal absorption of glucose is unaffected, as is its reabsorption from the urine by the cells of the proximal tubules of the kidneys. Glucose uptake by most of the brain and the red blood cells is also normal.

In the tissues in which insulin increases the number of GLUTs in cell membranes, the rate of phosphorylation of the glucose, once it has entered the cells, is regulated by other hormones. Growth hormone and cortisol both inhibit phosphorylation in certain tissues. Transport is normally so rapid that it is not a rate-limiting step in glucose metabolism. However, it is rate-limiting in B cells.

 Increased ketone uptake

 Increased K+ uptake

You'll just need to access the port 9000 of the Docker engine where portainer is running using your browser.

So if they choose to play the video, do they get some other prompt to accept cookies from YouTube BEFORE the video will play?

identification of resources; manipulation of resources through representations; self-descriptive messages; and, hypermedia as the engine of application state

the average docking score increase

select an origin

is a statement not made by us only; although it may seem a sufficiently marvellous and incredible assertion to those who have a reputation as philosophers among Greeks and Barbarians, by some of whom, however, an idea of His existence seems to have been entertained, in their acknowledging that all things were created by the word or reason of God.

But to us, who distinguish God from matter, and teach that matter is one thing and God another, and that they are separated by a wide interval (for that the Deity is uncreated and eternal, to be beheld by the understanding and reason alone, while matter is created and perishable),

continuous rather than a discrete variable, a relative rather thanan absolute term

Mining can include extraction of metals and minerals, like coal, diamond, gold, silver, platinum, copper, tin and iron. Mining can also include other things like oil and natural gas.

Presentation

According to man bash, however, non-interactive shells don't even read these files:

\curl

The sodium-restricted diet group received a regimen aiming a maximum intake of 3 g of sodium per day (equivalent to 7.5 g of sodium chloride).

You do need the double quotes in other cases, in particular in export VAR="${VAR1}" (which can equivalently be written export "VAR=${VAR1}") in many shells (POSIX leaves this case open).

How Does Olive Oil Lose It's Virginity?

Astronomers are still trying to accurately measure the shape of the universe.

universe is determined by its density, which is the amount of mass per volume.

nforced by moving the , hole population several miles in-land

lliplllatc in writing

On a recurring basis,subscription listens would be tallied and payouts wouldbe made to artists by a transparent, auditable subscrip-tion system running on the Audius blockchain.

Risk assessment◕Risk management strategy○Supply chain risk management◑

Risk assessment

none of them analyzed the threat of, and vulnerabilities to, a cyberattack spanning all three interconnections.

Problem definition and risk assessment

Problem definition and risk assessment.Addresses the particular national problems, assesses the risks to critical assets and operations—including the threats to, and vulnerabilities of, critical operations—and discusses the quality of data available regarding the risk assessment.

Further, federal agencies have performed three assessments of the potential impacts of cyberattacks on the industrial control systems supporting the grid.

The electric grid is becoming more vulnerable to cyberattacks via (1) industrial control systems, (2) consumer Internet of Things (IoT)45devices connected to the grid’s distribution network, and (3) the global positioning system (GPS).

3. Letter Regarding the Northwest College Personnel Association Student Relocation Committee

Let's make the example even easier. function convertDate<T extends string | undefined>(isoDate?: string): T { return undefined } 'undefined' is assignable to the constraint of type 'T' Means: What you return in the function (undefined), matches the constraints of your generic type parameter T (extends string | undefined). , but 'T' could be instantiated with a different subtype of constraint 'string | undefined'. Means: TypeScript does not consider that as safe. What if you defined your function like this at compile time: // expects string return type according to generics // but you return undefined in function body const res = convertDate<string>("2019-08-16T16:48:33Z") Then according to your signature, you expect the return type to be string. But at runtime that is not the case! This discrepancy that T can be instantiated with a different subtype (here string) than you return in the function (undefined) is expressed with the TypeScript error.

Both of the below are valid as far as T extends (...args: any[]) => any goes logFn((a, b) => a + b) logFn((a, b, c) => c) But if you refer back to the example I gave, the inner definition as: return (a, b) => fn(a, b); So option 2. will throw an error here, which is why typescript is warning you about it.

const renderMapping: { [l in letters]: renderFunction<l>; } = { 'a': (a: 'a') => 'alpha', 'b': (b: 'b') => 'bravo', }; type renderFunction<l extends letters> = (letter: l) => string; function renderLetter<l extends letters>(letter: l): renderFunction<l> { return renderMapping[letter]; }

The identity of a storyteller gives credibility

enhanced by choices they made through which they became “organizers’

routinely re-enact the practice of curating the information that comes their way.

Warum ist überhaupt Seiendes und nicht vielmehr Nichts? Das ist die Frage. Vermutlich ist dies keine beliebige Frage. »War- um ist überhaupt Seiendes und nicht vielmehr Nichts?« — das ist offensichtlich die erste aller Fragen. Die erste, freilich nicht in der Ordnung der zeitlichen Aufeinanderfolge der Fragen. Der einzelne Mensch sowohl wie die Völker fragen auf ihrem geschichtlichen Gang durch die Zeit vieles. Sie erkunden und durchsuchen und prüfen Vielerlei, bevor sie auf die Frage sto- ßen: »Warum ist überhaupt Seiendes und nicht vielmehr Nichts?« Viele stoßen überhaupt nie auf diese Frage, wenn das heißen soll, nicht nur den Fragesatz als ausgesagten hören und lesen, sondern: die Frage fragen, d. h. sie zustandbringen, sie stellen, sich in den Zustand dieses Fragens nötigen. Und dennoch! Jeder wird einmal, vielleicht sogar dann und wann, von der verborgenen Macht dieser Frage gestreift, ohne recht zu fassen, was ihm geschieht. In einer großen Verzweif- lung z. B., wo alles Gewicht aus den Dingen schwinden will und jeder Sinn sich verdunkelt, steht die Frage auf.

This is useful if just a subset of the operations need the API key

API keys are generally not considered secure; they are typically accessible to clients, making it easy for someone to steal an API key. Once the key is stolen, it has no expiration, so it may be used indefinitely, unless the project owner revokes or regenerates the key

Then Balbuena argues that there would be no music were it not for poetry.

of any State to the contrary notwithstanding."

After this declaration, it can scarcely be necessary to say that the existence of State banks can have no possible influence on the question.

axation, it is said, does not necessarily and unavoidably destroy. To carry it to the excess of destruction would be an abuse, to presume which would banish that confidence which is essential to all Government

The men who drew and adopted this amendment had experienced the embarrassments resulting from the insertion of this word in the Articles of Confederation, and probably omitted it to avoid those embarrassments.

Of consequence, when they act, they act in their States. But the measures they adopt do not, on that account, cease to be the measures of the people themselves, or become the measures of the State governments

Unless otherwise specified, input will be cast to float64

Abstract

Size and region parameters given as percentages and the rotation parameter allow positive floating point number values

INTRODUCTION

numerous studies have found individual differences in learners’engagement and achievement in MOOCs

understanding could be further enriched by integrating other temporal analysis methods.

). A consideration of temporal order can include attention directly to which events commonly follow others (either directly or after some lag), rates of transition from one state to another, similarities in sequences, or the presence of higher level phases of activity.