132 Matching Annotations
  1. Mar 2024
    1. do you seriously think the Future Of Interaction should be a single finger?

      The next time you make breakfast, pay attention to the exquisitely intricate choreography of opening cupboards and pouring the milk — notice how your limbs move in space, how effortlessly you use your weight and balance. The only reason your mind doesn't explode every morning from the sheer awesomeness of your balletic achievement is that everyone else in the world can do this as well. With an entire body at your command

      References

      Victor, B. (2011). A brief rant on the future of interaction design. Tomado de https://worrydream.com/ABriefRantOnTheFutureOfInteractionDesign/

  2. Jan 2024
    1. This is true for other tasks besides design — frontend implementation, backend implementation, QA, etc — would we create unique types for each? Our suggestion here to teams today is often to break down the work into issues, or now tasks, for each uniquely assignable/trackable piece of work. You could do the same for design, where the task or issue is used to track status, discuss progress and maybe even WIP, but is focused on being SSOT for status rather than design.
    2. Personally I think we could get a ton more benefits and would also be able to pull new users into our platform by finding better ways to integrate/link/connect/display Figma in our work item objects. Today the biggest downside for "Design management" is that it's basically just a copy of what's happening inside of Figma that has to be manually kept in sync and requires users to constantly switch back and forth:
  3. Nov 2023
    1. you can train them it has memory you can train it you can take a a trained one and a naive one and fuse them they 00:39:24 they'll fuse together and then the memory sort of propagates and the naive one will now remember you know have the memory that that the other one had um no nerves no no brain um single cell
      • for: Michael Levin - slime mold experiment, question - new theory of consciousness from a single cell

      • question

        • is it possible that a theory can be constructed to explain consciousness from the behavior of a single cell organism such as a slime mold?
  4. Oct 2023
    1. Eukaryotic single-celled organisms appear in the fossil record perhaps by 1.6 BYA (Knoll et al., 2006). Yet for a “boring billion” years of evolutionary history, they remain minor components in bacterial-dominated ecosystems before explosively radiating as large, multicellular species in an Ediacaran and Cambrian MST. Eukaryotes are obviously essential for this MST, as all animals, plants and fungi are eukaryotes. However, the initial appearance of eukaryotic cells seems insufficient for a MST.
      • for: example, example - MET and FET insufficient for MST

      • example: MET and FET insufficient for MST

      • paraphrase

        • Eukaryotic single-celled organisms appear in the fossil record by approx. 1.6 BYA (Knoll et al., 2006).
        • Yet for a “boring billion” years of evolutionary history, they remain minor components in bacterial-dominated ecosystems
          • before explosively radiating as large, multicellular species in
            • an Ediacaran and
            • Cambrian MST.
        • Eukaryotes are obviously essential for this MST, as all
          • animals,
          • plants and
          • fungi
        • are eukaryotes.

        • However, the initial appearance of eukaryotic cells seems insufficient for a MST

  5. Sep 2023
    1. ctually, the reed in the oboe, cor anglais,bassoon and double bassoon is made of two pieces of cane bound together: allthese are therefore 'double-reed' instruments. The clarinets and saxophones,on the other hand, are 'single-reed' instruments
  6. Jun 2023
    1. A Single-Scale ApproachThe chord structure of the A sections of rhythm changes can be reduced to the fundamentalframework shown in Figure 19.5.While mm. 1–4 of any A section feature a tonic prolongation, mm. 5–8 are morecomplicated even at the background level. For instance, the predominant in mm. 6, 14,and 30 can take the form of major 7th or dominant 7th chords. Also, the tonally closed256 INTERMEDIATEFIGURE 19.5 Fundamental Harmonic Frameworks
    1. In the layered architecture pattern, each layer fulfills a specific responsibility and role within the application. Some focus on user interface logic, while others handle the execution of business rules. These layers complement each other's unique purposes, but they aren't explicitly reliant on one another to perform their own tasks.
  7. May 2023
  8. Feb 2023
    1. Event Replay: If we find a past event was incorrect, we can compute the consequences by reversing it and later events and then replaying the new event and later events. (Or indeed by throwing away the application state and replaying all events with the correct event in sequence.) The same technique can handle events received in the wrong sequence - a common problem with systems that communicate with asynchronous messaging.
  9. Jan 2023
    1. It’s far more complicated than that, obviously. Different parts of this process are going on all the time. While working on one chapter, I’m also capturing and working on unrelated—for the time being at least—notes on other topics that interest me, including stuff that might well end up in future books.

      Because reading, annotating/note taking, and occasional outlining and writing can be broken down into small, concrete building blocks, each part of the process can be done separately and discretely with relatively easy ability to shift from one part of the process to another.

      Importantly, one can be working on multiple different high level projects (content production: writing, audio, video, etc.) simultaneously in a way which doesn't break the flow of one's immediate reading. While a particular note within a piece may not come to fruition within a current imagined project, it may spark an idea for a future as yet unimagined project.


      Aside: It would seem that Ryan Holiday's descriptions of his process are discrete with respect to each individual project. He's never mentioned using or reusing notes from past projects for current or future projects. He's even gone to the level that he creates custom note cards for his current project which have a title pre-printed on them.

      Does this pre-titling help to provide him with more singular focus for his specific workflow? Some who may be prone to being side-tracked or with specific ADHD issues may need or be helped by these visual and workflow cues to stay on task, and as a result be helped by them. For others it may hinder their workflows and creativity.

      This process may be different for beginning students or single project writers versus career writers (academics, journalists, fiction and non-fiction writers).


      As a concrete example of the above, I personally made a note here about Darwin and Lamarck for a separate interest in evolution which falls outside of my immediate area of interest with respect to note taking and writing output.

  10. Dec 2022
    1. Since there is no measurable performance advantage for either, any time (however marginal) spent thinking or talking about a choice between the two is wasted. When you prefer single quoted strings, you have to think when you need interpolation. When you use double quoted strings, you never have to think. (I'd also add, anecdotally, that apostrophes are more prevalent in strings than double quotes, which again means less thinking when using double-quoted strings.) Therefore always using double-quoted strings results in the least possible wasted time and effort.
  11. Nov 2022
    1. Primers to target the DXS gene24 (one copy per genome) and the ampicillin resistance gene on the plasmid were created using the Primer3Plus design tool
    1. But what about a Refresh Token flow? When using a refresh token, confidential clients also have to authenticate. Public clients, such as browser-based applications, do not authenticate during the Refresh Token flow. So in a typical frontend application, refresh tokens issued to frontend web applications are bearer tokens.   In practice, this means that if an attacker manages to steal a refresh token from a frontend application, they can use that token in a Refresh Token flow. To counter such attacks, the OAuth 2.0 specifications mandate that browser-based applications apply a security measure known as refresh token rotation.
    1. highly recommended that the resulting image be just one concern per container; predominantly this means just one process per container, so there is no need for a full init system

      container images: whether to use full init process: implied here: don't need to if only using for single process (which doesn't fork, etc.)

  12. Oct 2022
    1. https://www.denizcemonduygu.com/philo/browse/

      History of Philosophy: Summarized & Visualized

      This could be thought of as a form of digital, single-project zettelkasten dedicated to philosophy. It's got people, sources, and ideas which are cross linked in a Luhmann-sense (without numbering) though not in a topical index-sense. Interestingly it has not only a spatial interface and shows spatial relationships between people and ideas over time using a timeline, but it also indicates—using colored links—the ideas of disagreement/contrast/refutation and agreement/similarity/expansion.

      What other (digital) tools of thought provide these sorts of visualization affordances?

    1. Andere Sammlungen sind ihrem Verwendungszweck nie zugeführt worden. Der Germanist Friedrich Kittler etwa legte Karteikarten zu allen Farben an, die dem Mond in der Lyrik zugeschrieben worden sind. Das Buch dazu könnte jemand mit Hilfe dieser Zettel schreiben.

      machine translation (Google):

      Other collections have never been used for their intended purpose. The Germanist Friedrich Kittler, for example, created index cards for all the colors that were ascribed to the moon in poetry. Someone could write the book about it with the help of these slips of paper.

      Germanist Friedrich Kittler collected index cards with all the colors that were ascribed to the moon in poetry. He never did anything with his collection, but it has been suggested that one could write a book with his research collection.

    2. Nicht wenige Kästen sind nur für ein einziges Buch angelegt worden, Siegfried Kracauers Sammlungen etwa zu seiner Monographie über Jacques Offenbach, das Bildarchiv des Historikers Reinhart Koselleck mit Abteilungen Tausender Fotos von Reiterdenkmälern beispielsweise oder der Kasten des Romanisten Hans Robert Jauß, in dem er für seine Habilitationsschrift mittelalterliche Tiernamen und -eigenschaften verzettelte.

      machine translation (Google)

      Quite a few boxes have been created for just one book, Siegfried Kracauer's collections for his monograph on Jacques Offenbach, for example, the photo archive of the historian Reinhart Koselleck with sections of thousands of photos of equestrian monuments, for example, or the box by the Romanist Hans Robert Jauß, in which he wrote for his Habilitation dissertation bogged down medieval animal names and characteristics.

      A zettelkasten need not be a lifetime practice and historically many were created for supporting a specific project or ultimate work. Examples can be seen in the work of both Robert Green and his former assistant Ryan Holiday who kept separate collections for each of their books, as well as those displayed at the German Literature Archive in Marbach (2013) including Siegfried Kracauer (for a monograph on Jacques Offenbach), Reinhart Koselleck (equestrian related photos), Hans Robert Jauß (a dissertation on medieval animal names and characteristics).

  13. Sep 2022
    1. There are also some advantages to a multi-file YAML format OpenAPI definition: Reuse schema objects to keep things DRY (don't repeat yourself) Smaller diffs compared to JSON (especially for markdown descriptions) Easier to navigate Easier to edit with confidence
    1. need to be united in one single place

      often repeated advice, especially in the modern period.

    2. The rigidness and immobility of the note book pages, based on the papern stamp andimmobility of the individual notes, prevents quick and time-saving retrieval and applicationof the content and therefore proves the note book process to be inappropriate. The only tworeasons that this process is still commonly found in the studies of many is that firstly they donot know any better, and that secondly a total immersion into a very specialized field ofscientific research often makes information retrieval easier if not unnecessary.

      Just like Heyde indicated about the slip box note taking system with respect to traditional notebook based systems in 1931, one of the reasons we still aren't broadly using Heyde's system is that we "do not know any better". This is compounded with the fact that the computer revolution makes information retrieval much easier than it had been before. However there is such an information glut and limitations to search, particularly if it's stored in multiple places, that it may be advisable to go back to some of these older, well-tried methods.

      Link to ideas of "single source" of notes as opposed to multiple storage locations as is seen in social media spaces in the 2010-2020s.

    1. As a reminder, the JSON Schema is not the source of truth for the Specification. In cases of conflicts between the Specification itself and the JSON Schema, the Specification wins.
    1. As a reminder, the JSON Schema is not the source of truth for the Specification. In cases of conflicts between the Specification itself and the JSON Schema, the Specification wins. Also, some Specification constraints cannot be represented with the JSON Schema so it's highly recommended to employ other methods to ensure compliance.
  14. Aug 2022
    1. Beanstalk, a stablecoin protocol, found itself susceptible to governance attack via flashloan

      flashloans to acquire gov tokens for malicious proposals, e.g., to seize $182M of Beanstal's reserves.

  15. May 2022
    1. therefore the gases should be removed from the condenser. This can be achieved byinstalling vacuum pumps, compressors, or steam ejectors. The condenser heat removalis done either by using a cooling tower or through cold air circulation in the condenser.The condensate forms a small fraction of the cooling water circuit, a large portion ofwhich is then evaporated and dispersed into the atmosphere by the cooling tower. Thecooling water surplus (blow down) is disposed of in shallow injection wells. In singleflash condensation system, the condensate does have direct contact with the coolingwater.
    2. Single flash power plants are classified according to their steam turbines types, i.e., theturbine exit conditions. Two such basic types are the single flash with a condensationsystem and the single flash back pressure system. In the first type, a condenser oper-ating at very low pressure is used to condensate the steam leaving the steam turbine.The condenser should operate at low vacuum pressure to maintain a large enthalpy dif-ference across the expansion process of the steam turbine, hence resulting in a higherpower output. The geothermal fluid usually contains non-condensable gases which arecollected at the condenser. Such a collection of gases may raise the condenser pressure,
  16. Apr 2022
    1. This is not a path I'd recommend for small-to-medium-sized teams, but if you're inside a large organization committed to making SPAs with high walls between front-end and back-end departments, it might make sense.
  17. Feb 2022
  18. Jan 2022
    1. Oh, I just figured out a workaround for my project, in case it helps someone. If you want the source of truth on the prop to come from the child component, then leave it undefined in the parent. Then, you can make the reactive variable have a condition on the presence of that variable. eg: <script> let prop; $: prop && console.log(prop); </script> <Child bind:prop/> Might not work for every use case but maybe that helps someone.
  19. Nov 2021
  20. Sep 2021
    1. Lee, J. W., Su, Y., Baloni, P., Chen, D., Pavlovitch-Bedzyk, A. J., Yuan, D., Duvvuri, V. R., Ng, R. H., Choi, J., Xie, J., Zhang, R., Murray, K., Kornilov, S., Smith, B., Magis, A. T., Hoon, D. S. B., Hadlock, J. J., Goldman, J. D., Price, N. D., … Heath, J. R. (2021). Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19. Nature Biotechnology, 1–11. https://doi.org/10.1038/s41587-021-01020-4

  21. Jul 2021
    1. Ben: That's all I can do. But I'm still grateful I did very well and my family's not hurting. If I felt that they were hurting, I would risk it all and head back. But, they're comfortable, they're doing well. And I think, well I feel that I set a standard for them, to strive to be more, to strive because they all had, including my wife, when we married she was kind of shy and her self-esteem—not that she had low self-esteem—but she really didn't believe that much in herself. But right now, she's shining, she's doing really well, and she's holding it together for both kids at that age to still be living with her, other than my son right now in college, that he went, that's to say a lot for two parents. But for a single parent, you gotta hand it to her.

      Reflections

  22. Jun 2021
  23. May 2021
  24. Apr 2021
  25. Mar 2021
    1. Voysey, M., Costa Clemens, S. A., Madhi, S. A., Weckx, L. Y., Folegatti, P. M., Aley, P. K., Angus, B. J., Baillie, V., Barnabas, S. L., Bhorat, Q. E., Bibi, S., Briner, C., Cicconi, P., Clutterbuck, E., Collins, A. M., Cutland, C., Darton, T., Dheda, K., Douglas, A. D., … Group, O. C. V. T. (2021). Single Dose Administration, And The Influence Of The Timing Of The Booster Dose On Immunogenicity and Efficacy Of ChAdOx1 nCoV-19 (AZD1222) Vaccine (SSRN Scholarly Paper ID 3777268). Social Science Research Network. https://papers.ssrn.com/abstract=3777268

    1. The elimination of what is arguably the biggest monoculture in the history of software development would mean that we, the community, could finally take charge of both languages and run-times, and start to iterate and grow these independently of browser/server platforms, vendors, and organizations, all pulling in different directions, struggling for control of standards, and (perhaps most importantly) freeing the entire community of developers from the group pressure of One Language To Rule Them All.
  26. afarkas.github.io afarkas.github.io
    1. Webshim is also more than a polyfill, it has become a UI component and widget library. Webshim enables a developer to also enhance HTML5 capable browsers with more highly customizable, extensible and flexible UI components and widgets.

      And now that it's deprecated (presumably due to no longer needing these polyfills), not only do the polyfills go away (no longer maintained), but also these unrelated "extras" that some of us may have been depending on are now going away with no replacement ...

      If those were in a separate package, then there would have been some chance of the "extras" package being updated to work without the base webshims polyfills.

      In particular, I was using $.webshims.addCustomValidityRule which adds something that you can't do in plain HTML5 (that I can tell), so it isn't a polyfill...

  27. Feb 2021
    1. An endpoint links your routing with your business code. The idea is that your controllers are pure HTTP routers, calling the respective endpoint for each action. From there, the endpoint takes over, handles authentication, policies, executing the domain code, interpreting the result, and providing hooks to render a response.
    1. Trust me, I thought a lot about #validate and its semantics, and I am gonna make it even more "SRP" by making Form#errors and #valid? semi-public. All that happens via #validate reducing the possible wrong usage for users.
    2. About #validate which fill attributes of the form, I think it's a problem of architecture and clarity. If you respect the Single Responsabilty Principle, you must to have two methods. This is wrong. SRP means your class does exactly one thing, which is reflected in a single public method. The more methods you expose, the less SRP you go.
    3. About #validate which fill attributes of the form, I think it's a problem of architecture and clarity. If you respect the Single Responsabilty Principle, you must to have two methods. The validate method do two thing really different.
    1. Now let me ask you, do you write JS for a single page application differently from a "traditional" web application? I sure hope you do! In a "traditional" application, you can get away with being sloppy because every time the user navigates to a new page, their browser destroys the DOM and the JavaScript context. SPAs, though, require a more thoughtful approach.
    2. Turbolinks is a Single-Page Application Turbolinks doesn't just give you some of the benefits of a single-page app. Turbolinks is a single page app. Think about it: When someone visits your site, you serve them some HTML and Javascript. The JavaScript takes over and manages all subsequent changes to the DOM. If that's not a single-page app, I don't know what is.
    3. Our app is mostly about displaying pages of static information. We crunch a lot of data to generate a single error report page.
    4. Honeybadger isn't a single page app, and it probably won't ever be. SPAs just don't make sense for our technical requirements.
  28. Jan 2021
    1. It appears that Canonical is continuing it's vice grip of unliateral, maybe dictatorial control on the development of Snap to the benefit of Ubuntu, but to the detriment of groups like Linuxmint, and all other non-Ubuntu based Linux distributions - like CentOS/Redhat, Suse/openSuSe, Solus, Arch/Manjaro, PCLinuxOS, etc, that are pushing Flatpak as a truly cross-distro application solution that works equally well and non-problematic for all. .
    2. What's wrong here is Canonical trying to position itself as a powerhouse and ascertain control over Linux users.
    3. I suppose it means 2 things, first, you get official support and warranty, and second, the distros will be Secure Boot approved in the UEFI, instead of distro makers having to figuratively ask Microsoft for pretty please permission.
    4. If we're not careful, it could become the new 'systemd' problem It probably already is. I don't want to sound too Stallman, but this is the inevitable "company" influence you'll always have. Companies do have their objectives which they will pursue determinedly, since they are not philanthropic (no judgment, just observation). Systemd and Red Hat. Nvidia and their drivers. Google and Android. Apple and iOS. Manufacturers with MS only support. And Canonical also has a history there: the Amazon links, Unity, Mir, and now snap.
    1. What we didn't want it to be was for Canonical to control the distribution of software between distributions and 3rd party editors, to prevent direct distribution from editors, to make it so software worked better in Ubuntu than anywhere else and to make its store a requirement,"
  29. Dec 2020
    1. it focuses on compiling non-standard language extensions: JSX, TypeScript, and Flow. Because of this smaller scope, Sucrase can get away with an architecture that is much more performant but less extensible
  30. Nov 2020
    1. So, how does an SPA work? JavaScript loads in the browser and loads data from an API. Most of the rendering is done on the client Side. But search engine bots have a hard time indexing the page because it doesn't have much without JS.
  31. Oct 2020
    1. In the next major, we'll start copying the ref onto both the props and the element.ref. React will now use the props.ref as the source of truth for forwardRef and classes and it will still create a shallow copy of props that excludes the ref in these cases. At the same time, we'll add a getter for element.ref in DEV that warns if you access it. The upgrade path is now to just access it off props if you need it from the element.
    1. Instead of using classes and local state, Deku just uses functions and pushes the responsibility of all state management and side-effects onto tools like Redux.
    1. A class should only have a single responsibility, that is, only changes to one part of the software's specification should be able to affect the specification of the class.
    1. We will also need to make a tweak to our package.json file to ensure that if we reload on a page we have navigated to, for example, /blog, we will not receive a server error and it will load the appropriate route.
  32. Sep 2020
    1. We don't want to rely on there being a single root element - or prevent ourselves from ever implementing named slots without a single root node - and so there's not anything to apply the class to or the transition to.
  33. Aug 2020
    1. Felipe, L. S., Vercruysse, T., Sharma, S., Ma, J., Lemmens, V., Looveren, D. van, Javarappa, M. P. A., Boudewijns, R., Malengier-Devlies, B., Kaptein, S. F., Liesenborghs, L., Keyzer, C. D., Bervoets, L., Rasulova, M., Seldeslachts, L., Jansen, S., Yakass, M. B., Quaye, O., Li, L.-H., … Dallmeier, K. (2020). A single-dose live-attenuated YF17D-vectored SARS-CoV2 vaccine candidate. BioRxiv, 2020.07.08.193045. https://doi.org/10.1101/2020.07.08.193045

    1. Do not include the same information in multiple places. Link to a SSOT instead.
    2. There is a temptation to summarize the information on another page. This will cause the information to live in two places. Instead, link to the SSOT and explain why it is important to consume the information
    1. Unterman, A., Sumida, T. S., Nouri, N., Yan, X., Zhao, A. Y., Gasque, V., Schupp, J. C., Asashima, H., Liu, Y., Cosme, C., Deng, W., Chen, M., Raredon, M. S. B., Hoehn, K., Wang, G., Wang, Z., Deiuliis, G., Ravindra, N. G., Li, N., … Cruz, C. S. D. (2020). Single-Cell Omics Reveals Dyssynchrony of the Innate and Adaptive Immune System in Progressive COVID-19. MedRxiv, 2020.07.16.20153437. https://doi.org/10.1101/2020.07.16.20153437

  34. Jul 2020
    1. In your environment you may want to always configure internationalization, routers, user data etc. If you have many different React roots it can be a pain to set up configuration nodes all over the place. By creating your own wrapper you can unify that configuration into one place.
    1. Sapoval, N., Mahmoud, M., Jochum, M. D., Liu, Y., Elworth, R. A. L., Wang, Q., Albin, D., Ogilvie, H., Lee, M. D., Villapol, S., Hernandez, K., Berry, I. M., Foox, J., Beheshti, A., Ternus, K., Aagaard, K. M., Posada, D., Mason, C., Sedlazeck, F. J., & Treangen, T. J. (2020). Hidden genomic diversity of SARS-CoV-2: Implications for qRT-PCR diagnostics and transmission. BioRxiv, 2020.07.02.184481. https://doi.org/10.1101/2020.07.02.184481

  35. Jun 2020
  36. May 2020
  37. touchpoints-demo.app.cloud.gov touchpoints-demo.app.cloud.gov
    1. Touchpoints uses Login.gov to handle user accounts. Once you authenticate with Login.gov, you will be signed in and redirected back to Touchpoints.
    1. Not building a static site? No worries there, React Static works as an SPA too, even if there is only a single index.html file.
    1. Code Owners allows for a version controlled single source of truth file outlining the exact GitLab users or groups that own certain files or paths in a repository.
  38. Apr 2020
    1. Before we get to passwords, surely you already have in mind that Google knows everything about you. It knows what websites you’ve visited, it knows where you’ve been in the real world thanks to Android and Google Maps, it knows who your friends are thanks to Google Photos. All of that information is readily available if you log in to your Google account. You already have good reason to treat the password for your Google account as if it’s a state secret.
    2. You already have good reason to treat the password for your Google account as if it’s a state secret. But now the stakes are higher. You’re trusting Google with the passwords that protect the rest of your life – your bank, your shopping, your travel, your private life. If someone learns or guesses your Google account password, you are completely compromised. The password has to be complex and unique. You have to treat your Google account password with the same care as a LastPass user. Perhaps more so, because it’s easier to reset a Google account password. If your passwords are saved in Chrome, you should strongly consider using two-factor authentication to log into your Google account. I’ll talk about that in the next article.
    1. There are good preprints and bad preprints, just like there are with journal articles. Overall, do not be afraid to be scooped or plagiarized! Preprints also actually protect against scooping [21,22]. Preprints establish the priority of discovery as a formally published item. Therefore, a preprint acts as proof of provenance for research ideas, data, code, models, and results—all outputs and discoveries.
      • Salah satu alasan untuk tidak mengunggah preprint adalah takut idenya dicuri,

      • Ini adalah faktor budaya yang lain. Ketakutan yang tidak beralasan. Justru dengan mengunggah preprint, peneliti dapat mengklaim ide lebih awal.

      • Preprint ada yang bagus dan ada yang buruk, peninjauan akan ada di tangan pembaca. Ini adalah hambatan budaya berikutnya, ketika mayoritas pembaca ingin melimpahkan tanggungjawab untuk memverifikasi, memeriksa, dan menjamin kualitas suatu makalah kepada para peninjau.

      • Pengalihan tanggungjawab ini sulit dilakukan ketika dokumen PR sendiri tertutup, dan tidak lepas dari bias.

      • Selain itu, dosen akan menyalahi prinsip yang disebarluaskan kepada para mahasiswa, untuk membaca secara kritis.

  39. Mar 2020
    1. selected after transformation and used to inoculate liquid cultures

      Would the variability be the same if the colonies were picked from a streaked plate (from glycerol stock) instead of a transformation plate?

      I would expect the glycerol stock method to have more variability, but it would be good to test

  40. Jan 2020
    1. Arel’s responsibility is SQL query construction and optimization, and it knows very little about ActiveRecord’s Models and nothing about the database. Arel provides the basic building blocks for ActiveRecord.
  41. Aug 2019
    1. Sen. Bernie Sanders

      Supporters of the "Single-payers" method.

    2. The cost of a single-payer system would depend upon its design, benefit levels, and scope of coverage.

      It is impossible to provide a specific costing method, but only general methods. How is design dependent? What is the benefit level of? and the range means the limit of the "Single-payer" system?

    3. A “single-payer” health system is a government-controlled health care system. Government is the “single-payer.” In most versions of single-payer, most private health insurance is either outlawed or restricted, and most public health programs are absorbed into the single, national health insurance program.

      Explain the "Single-payer" system.

    4. What Is Single-Payer?

      The question is about the meaning of "Single-payer".

  42. Apr 2019
    1. Klotho-deficient mice have accelerated aging phenotypes, whereas overexpression of Klotho in mice extends lifespan. Klotho is an anti-aging single-pass membrane protein predominantly produced in the kidney, with shedding of the amino-terminal extracellular domain into the systemic circulation. Circulating levels of soluble Klotho decrease with age, and the klotho gene is associated with increased risk of age-related diseases. The three forms of Klotho protein have distinct functions. Membrane Klotho forms a complex with fibroblast growth factor (FGF) receptors, functions as an obligatory co-receptor for FGF23, which is involved in aging and the development of chronic diseases via regulation of Pi and vitamin D metabolism. Secreted Klotho functions as a humoral factor with pleiotropic activities including regulation of oxidative stress, growth factor signaling, and ion homeostasis. Secreted Klotho is also involved in organ protection. The intracellular form of Klotho suppresses inflammation-mediated cellular senescence and mineral metabolism. Herein we provide a brief overview of the structure and function and recent research about Klotho.
  43. Jan 2019
    1. the best performance is achieved by calling registerApplication immediately, but calling start after the AJAX request is completed.

      important note (and including paragraph) regarding how to achieve best performance when loading multiple apps (which is what single spa does...). Basically, registerApplication() first, but start() only after doing some other work, maybe like painting initial stuff on the web page.

    1. When called, this function should look at the URL to determine the active route and then create DOM elements, DOM event listeners, etc. to render content to the user

      this is the purpose of the mount function

    2. except that it doesn't have an HTML page

      I think they mean that it doesn't have its own html page with head and body section. Instead, it has only its own section of the DOM, without those 'upstream' parts.

    3. A reference to the singleSpa instance, itself. This is intended to allow applications and helper libraries to call singleSpa APIs without having to import it.

      important. can it be useful to share information between different apps called by single-spa? I know there are other recommended mechanisms for this in single-spa world but just a thought - could be useful for that.

    4. pass a reference to a common event bus so each app may talk to each other

      this seems like a recommended way to share events and data between multiple apps in one single-spa instance. i wonder how technically this should be implemented

  44. Aug 2018
  45. Jul 2018
    1. By mosaic, we mean that time is often simultaneouslyinhabited by multiple types of interaction that are forced to form a coherent whole. Unlikeconcepts like multi-tasking(doing multiple tasks ‘at once’) or polychronicity(a reported preference for doing multiple tasks at once) [44], mosaic timerefers to the negotiated merging of multiple social spheres into a layered or fitted set of simultaneous interactions

      Definition of mosaic time. Counters the idea (ideal?) of single purpose time.

      Is negotiated not imposed.

      Does not include multitasking or polychronicity.

    2. We call this prevailing temporal logic ‘circumscribed time.’ We use this label to highlight the underlying orientation to time as a resource that can, and should, be mastered. A circumscribed temporal logic infers that time should be harnessed into ‘productive’ capacity by approaching it as something that can be chunked, allocated to a single use, experienced linearly, and owned. In turn, the norms of society place the burden on individuals to manage and ‘balance’ time as a steward, optimizing this precious resource by way of control and active manipulation.

      Description of the elements of circumscribed time.

    3. Aligned with chunk-able time is the assumption that each chunk of time, or its particular gridded arrangement, is allocated to a single purpose.

      Definition of single purpose time.

      Design implication: How does single-purpose time align or conflict with multitasking and/or blurred task types that overlap home vs office, personal vs professional.

  46. Oct 2017
  47. Sep 2017
  48. Feb 2017
    1. Published in the days leading up to the 45th president’s inauguration, two new books purport to show a path forward for liberals in Trump’s America.
    2. In his introduction to “What We Do Now,” co-editor Dennis Johnson writes of the widespread “despair,” “grief” and “disillusionment” that followed the election.
  49. Oct 2016
    1. Which single sign-on services do you integrate with? Technically, single sign-on can work with any IDP that is SAML 2.0 compliant -- this includes services like Okta, Ping Identity, OneLogin, and Bitium.

      single sign-on

  50. Jun 2016
    1. The standard model of scholarly publishing assumes awork written by an author. There is typically a single authorwho receives full credit for theopusin question. By thesame token, the named author is held accountable for allclaims made in the text, excluding those attributed to othersvia citations. The appropriation of credit and allocation ofresponsibility thus go hand-in-hand, which makes for fairlystraightforward social accounting. The ethically informed,lone scholar has long been a popular figure, in both fact andscholarly mythology. Historically, authorship has beenviewed as a solitary profession, such that “when we picturewriting we see a solitary writer” (Brodkey, 1987, p. 55). Butthat model, as Price (1963) recognized almost three decadesago, is anachronistic as far as the great majority of contem-porary scientific, and much social scientific and humanistic,publishing is concerned.

      On "standard model" of authorship: lone authority and responsibility; how this is anachronistic.

  51. Mar 2016
  52. Oct 2015