2,377 Matching Annotations
  1. Dec 2021
    1. ReconfigBehSci on Twitter: “but it is not vaccinated people that are disproportionately filling up ICUs. For any government whose policy is guided by ICU capacity, limiting the transmission possibilities for the unvaccinated is now the point. It is frustrating to see someone continue to ignore this” / Twitter. (n.d.). Retrieved December 23, 2021, from https://twitter.com/SciBeh/status/1471088416246878211

    1. ReconfigBehSci. (2021, December 7). Given an estimate whereby the average person knows ca. 600 people, assuming 50% vaxxed, the average person would know 8 people who died of the vaccine. It is hard to believe numeracy is so low that people cannot see how crazy these “statistics” are... [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1468163579069280258

    1. Arieh Kovler. (2021, November 26). Israel has identified four cases of the B.1.1.529 variant, all recent travellers. One case, a 32-year-old woman returning from South Africa, was triple vaccinated with Pfizer and had her 3rd dose just two months ago. [Tweet]. @ariehkovler. https://twitter.com/ariehkovler/status/1464190991204859919

    1. Jay Varma. (2021, December 16). Um, we’ve never seen this before in #NYC. Test positivity doubling in three days 12/9—3.9% 12/10—4.2% 12/11—6.4% 12/12—7.8% Note: Test % is only for PCR & NYC does more per capita daily than most places ~67K PCR/day + 19K [reported] antigen over past few days (1/2) https://t.co/PhxsZq55jn [Tweet]. @DrJayVarma. https://twitter.com/DrJayVarma/status/1471485885447389186

    1. Eric Topol. (2020, November 28). This will go down in history as one of science and medical research’s greatest achievements. Perhaps the most impressive. I put together a preliminary timeline of some key milestones to show how several years of work were compressed into months. Https://t.co/BPcaZwDFkl [Tweet]. @EricTopol. https://twitter.com/EricTopol/status/1332771238771630080

    1. Garcia-Beltran, W. F., Denis, K. J. S., Hoelzemer, A., Lam, E. C., Nitido, A. D., Sheehan, M. L., Berrios, C., Ofoman, O., Chang, C. C., Hauser, B. M., Feldman, J., Gregory, D. J., Poznansky, M. C., Schmidt, A. G., Iafrate, A. J., Naranbhai, V., & Balazs, A. B. (2021). MRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant (p. 2021.12.14.21267755). https://doi.org/10.1101/2021.12.14.21267755

    1. Patone, M., Mei, X. W., Handunnetthi, L., Dixon, S., Zaccardi, F., Shankar-Hari, M., Watkinson, P., Khunti, K., Harnden, A., Coupland, C. A. C., Channon, K. M., Mills, N. L., Sheikh, A., & Hippisley-Cox, J. (2021). Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination or SARS-CoV-2 infection. Nature Medicine, 1–13. https://doi.org/10.1038/s41591-021-01630-0

    1. Bert Hubert’s excellent and widely shared article about Reverse Engineering the source code of the Pfizer-BioNTech SARS-CoV-2 Vaccine

      These 2 articles form an informational island on covid19 mRNA vaccines.

    1. Translational kinetics of mRNA-LNP delivered by different routes in vivo. Quantification of the bioluminescent signal measured in BALB/c mice injected with (A) 0.1 μg, (B) 1.0 μg or (C) 5.0 μg mRNA-LNPs by intradermal (i.d.), intramuscu

      Diagrams of the presence of proteins versus time in various administration methods in mouse

    1. In this mouse model, the mRNA hit the hepatocytes and caused them to make plenty of luciferase, but not for long: at Day 1, the livers were lit up like a used car lot, but by Day 3, everything was gone. At that point, though, there was still some light coming from the sites of injection.

      Where does all the mRNA end up, according to this 2015 study on mice](https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4624045/)?

      Here we learn stuff not reorted in the paper.

    1. Nature Portfolio. (2021, December 8). Estimates of COVID-19 vaccine uptake in the US based on large surveys that are used to guide policy-making decisions tend to overestimate the number of vaccinated individuals, according to research published in @Nature. Https://go.nature.com/3EBQPOh https://t.co/rSoclzWIdg [Tweet]. @NaturePortfolio. https://twitter.com/NaturePortfolio/status/1468633979364560899

    1. Dave Keating. (2021, December 8). Boris Johnson’s continued pretence that UK is one of the most vaccinated countries in the world, repeated again in press conference just now announcing new restrictions, is getting tiresome. That has not been the case for many many months, despite 🇬🇧🇺🇸 vaccine hoarding early on. Https://t.co/tQt6aXGtNI [Tweet]. @DaveKeating. https://twitter.com/DaveKeating/status/1468655107436802052

    1. Heitmann, J. S., Bilich, T., Tandler, C., Nelde, A., Maringer, Y., Marconato, M., Reusch, J., Jäger, S., Denk, M., Richter, M., Anton, L., Weber, L. M., Roerden, M., Bauer, J., Rieth, J., Wacker, M., Hörber, S., Peter, A., Meisner, C., … Walz, J. S. (2021). A COVID-19 peptide vaccine for the induction of SARS-CoV-2 T cell immunity. Nature, 1–9. https://doi.org/10.1038/s41586-021-04232-5

    1. mechanism responsible for blood clots arising from thrombosis with thrombocytopenia syndrome (TTS) following vaccination with AstraZeneca vaccine.

      covishield vaccine clotting problem

    1. Seth Trueger. (2021, June 26). friendly reminder that “more transmissible” is by itself REALLY BAD for a pandemic. Even small increases in R₀ mean more potential for spread, more cases, more deaths etc please get your vax & help others get theirs https://t.co/mlojYmp71j [Tweet]. @MDaware. https://twitter.com/MDaware/status/1408811800108355586

    1. Thiruvengadam, R., Awasthi, A., Medigeshi, G., Bhattacharya, S., Mani, S., Sivasubbu, S., Shrivastava, T., Samal, S., Rathna Murugesan, D., Koundinya Desiraju, B., Kshetrapal, P., Pandey, R., Scaria, V., Kumar Malik, P., Taneja, J., Binayke, A., Vohra, T., Zaheer, A., Rathore, D., … Garg, P. K. (2021). Effectiveness of ChAdOx1 nCoV-19 vaccine against SARS-CoV-2 infection during the delta (B.1.617.2) variant surge in India: A test-negative, case-control study and a mechanistic study of post-vaccination immune responses. The Lancet Infectious Diseases, S1473309921006800. https://doi.org/10.1016/S1473-3099(21)00680-0

  2. Nov 2021
    1. Δώστε ένα πακέτο στα μίνιονς του Kaiser και εύχομαι το billions να είναι ΚαλοPfizer Και όταν θα επέλθει η ανοσία στην αγέλη θα δούμε πόσες μέλισσες θα υπάρχουν στην κυψέλη και εν τέλει

      Στερεη αποψη για τον εμβολιασμό στον covid19.

    1. Thus, this study provides the basis to pursue further efficacy studies in non-human primate models or even initiate clinical phase I studies using the currently available vaccines.

      As of 26 Nov 2021, phase 1 studies have not yet begun for mucosal vaccines, not even in primates :-(

    1. Thiruvengadam, R., Awasthi, A., Medigeshi, G., Bhattacharya, S., Mani, S., Sivasubbu, S., Shrivastava, T., Samal, S., Murugesan, D. R., Desiraju, B. K., Kshetrapal, P., Pandey, R., Scaria, V., Malik, P. K., Taneja, J., Binayke, A., Vohra, T., Zaheer, A., Rathore, D., … Garg, P. K. (2021). Effectiveness of ChAdOx1 nCoV-19 vaccine against SARS-CoV-2 infection during the delta (B.1.617.2) variant surge in India: A test-negative, case-control study and a mechanistic study of post-vaccination immune responses. The Lancet Infectious Diseases, 0(0). https://doi.org/10.1016/S1473-3099(21)00680-0

    1. Stephen Reicher. (2021, November 26). 55.1% of the worlds population has had one dose of Covid vaccine. 29% in South Africa 10.1% in Africa as a whole Only 6% of Africans are fully vaccinated So is it any surprise new variants are arising from Africa? What doesn’t go around (as vaccine) Comes around (as Covid). Https://t.co/0X0vZ6flmc [Tweet]. @ReicherStephen. https://twitter.com/ReicherStephen/status/1464202267196858380

    1. ReconfigBehSci. (2021, November 23). query: Https://unherd.com/2021/11/the-lefts-covid-failure/ “Is there really no progressive criticism to be made about the quarantining of healthy individuals, when the latest research suggests there is a vanishingly small difference in terms of transmission between the vaccinated and the unvaccinated?” 1/2 [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1463146737804140558

    1. Seth Trueger. (2021, July 21). If seatbelts work so well why do we have airbags crumple zones speed limits licensing road signs traffic lights road safety engineering ambulances EMTs trauma centers brakes https://t.co/6x29wCOlwp [Tweet]. @MDaware. https://twitter.com/MDaware/status/1417680529160294401

    1. Tania Bubela. (2021, November 17). New resources on #COVID19vaccines & #pregnancy from the fantastic group @CDCofBC Indigenous Knowledge Translation Working Group. @HarlanPruden working to meet knowledge needs of Indigenous communities in ways that are meaningful. @ScienceUpFirst take note! @SFU_FHS @CaulfieldTim https://t.co/oK3WJUj9p6 [Tweet]. @bubela_tania. https://twitter.com/bubela_tania/status/1460776956379557889

    1. Walter, E. B., Talaat, K. R., Sabharwal, C., Gurtman, A., Lockhart, S., Paulsen, G. C., Barnett, E. D., Muñoz, F. M., Maldonado, Y., Pahud, B. A., Domachowske, J. B., Simões, E. A. F., Sarwar, U. N., Kitchin, N., Cunliffe, L., Rojo, P., Kuchar, E., Rämet, M., Munjal, I., … Gruber, W. C. (2021). Evaluation of the BNT162b2 Covid-19 Vaccine in Children 5 to 11 Years of Age. New England Journal of Medicine, NEJMoa2116298. https://doi.org/10.1056/NEJMoa2116298

    1. ReconfigBehSci. (2021, November 4). RT @DrTedros: We continue to hear excuses about why low-income countries have only received 0.4% of #COVID19 vaccines: 1. They can’t absorb… [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1456588731155165189