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adaptive systems likely activate innate cells through antibodies and cytokines
Long COVID
Damaged endothelial cells from initial viral infection circulate the blood a month after symptom onset https://doi.org/10.7554/eLife.64909
These will activate monocytes and neutrophils, but are also thought to facilitate clotting which will add to symptoms.
Importantly, this late in the disease recovery it is not surprising to note that IL-2 and other pro-T cell cytokines are elevated which correlates with enhanced effector T-cells https://doi.org/10.7554/eLife.64909
These adaptive cells along with autoantibodies likely propagate the effects of COVID-19 long term.
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This is Our Shot 🇨🇦 #ThisIsOurShotCA on Twitter: “Tonight is the night! LIVE Town Hall. Real experts. Real answers. 8 pm ET/ 5 pm PT. Tune in at https://t.co/FvdIjdi9SF https://t.co/4ugZ3kTaef” / Twitter. (n.d.). Retrieved June 28, 2021, from https://twitter.com/thisisourshotca/status/1395017500539097095
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A Marm Kilpatrick on Twitter: “How effective are vaccines vs severe & all disease, death, infection, & transmission? Very nice collection of studies assessing different aspects of vaccine protection by Julia Shapiro (on twitter?) @nataliexdean @betzhallo @ilongini & 2 others. Thread https://t.co/mhe0DufVtH” / Twitter. (n.d.). Retrieved June 28, 2021, from https://twitter.com/DiseaseEcology/status/1395848357461954563
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twitter.com twitter.com
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Jeremy Faust MD MS (ER physician) on Twitter: “Number of Covid cases among children in US: >4 million. Number of Covid deaths in US children: 300-400. Number of kids vaccinated: 7 million. Number of kids who died from vaccine-related myocarditis: Zero. #vaccinate @bhrenton @RickABright @angie_rasmussen @celinegounder” / Twitter. (n.d.). Retrieved June 28, 2021, from https://twitter.com/jeremyfaust/status/1408880589319647243?s=20
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Jeffrey Ely on Twitter: “The base-rate fallacy is about to become a daily nuisance when it comes to processing outbreak data in highly vaccinated societies. Here’s a cautionary tale.” / Twitter. (n.d.). Retrieved June 28, 2021, from https://twitter.com/Jeffely/status/1408500890999328770
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Christophe Fraser 💙 on Twitter: “Reading Cummings accounts of early creation of Test & Trace, a question I have is when and how it was morphed from aiming to find ~30 contacts per index case, needed to contain spread, into a service that contacts 2-4 contacts per index case, mostly within household.” / Twitter. (n.d.). Retrieved June 28, 2021, from https://twitter.com/ChristoPhraser/status/1408454903249477632
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twitter.com twitter.com
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Eric Topol on Twitter: “As the Delta variant (B.1.617.2) becomes dominant throughout the world, there are 2 patterns emerging: —Countries w/ low vaccination rates are seeing both case and fatality rates increase—Countries w/ high vaccination rate: Some case increase and minimal to no fatality increase https://t.co/sSE4RlSeUJ” / Twitter. (n.d.). Retrieved June 28, 2021, from https://twitter.com/EricTopol/status/1408195243279667204
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twitter.com twitter.com
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Spenser Lang on Twitter: “Astounding how we let politics influence public health. Republican, Democrat, who cares—Get vaccinated! Https://t.co/oOKZ5PcTqB” / Twitter. (n.d.). Retrieved June 28, 2021, from https://twitter.com/spenserlang/status/1408126711456276488
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the Guardian. ‘TUC Says Covid Vaccine Efforts Hindered by Lack of Paid Time off for Jab’, 22 March 2021. http://www.theguardian.com/politics/2021/mar/22/tuc-says-covid-vaccine-efforts-hindered-by-lack-of-paid-time-off-for-jab.
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Sallam, M. (2021). COVID-19 Vaccine Hesitancy Worldwide: A Concise Systematic Review of Vaccine Acceptance Rates. Vaccines, 9(2), 160. https://doi.org/10.3390/vaccines9020160
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Wise, J. (2021). Covid-19: Should we be worried about reports of myocarditis and pericarditis after mRNA vaccines? BMJ, 373, n1635. https://doi.org/10.1136/bmj.n1635
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Rosenfeld, D. L., & Tomiyama, A. J. (2021). Jab My Arm, Not My Morality: Perceived Moral Reproach as a Barrier to COVID-19 Vaccine Uptake. PsyArXiv. https://doi.org/10.31234/osf.io/ycbrd
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nautil.us nautil.us
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Levenson, T. (2021, June 23). When a Good Scientist Is the Wrong Source. Nautilus. http://nautil.us/issue/102/hidden-truths/when-a-good-scientist-is-the-wrong-source
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Mills, F., Symons, D. C., & Carter, D. H. (2021). Exploring the Role of Enforcement in Promoting Adherence with Protective Behaviours During COVID-19. PsyArXiv. https://doi.org/10.31234/osf.io/89sj3
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Julia Chatterley. (2021, May 21). "I think the #EU needs to be on the right side of history.” @JNkengasong Head of @AfricaCDC welcomes news of $1.2 bn EU investment but says the continent can produce vaccines at scale IF #patents are waived. ‘The time is always right to do the right thing...’ PART I https://t.co/N1Xw9QLFhu [Tweet]. @jchatterleyCNN. https://twitter.com/jchatterleyCNN/status/1395755122320416775
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Deepti Gurdasani on Twitter: “I’m still utterly stunned by yesterday’s events—Let me go over this in chronological order & why I’m shocked. - First, in the morning yesterday, we saw a ‘leaked’ report to FT which reported on @PHE_uk data that was not public at the time🧵” / Twitter. (n.d.). Retrieved June 27, 2021, from https://twitter.com/dgurdasani1/status/1396373990986375171
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Stephan Lewandowsky. (2021, May 4). And of course… more myths have to be rebutted on our myths page: Https://t.co/uZ5PTpNHff (although it is good to see how many myths are just variants of older zombie arguments) 3/n [Tweet]. @STWorg. https://twitter.com/STWorg/status/1389549507206172674
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Paul Kedrosky. (2021, June 8). Air passengers in the U.S. yesterday were up 20% week-over-week, the biggest advance since February, and the highest total daily passengers—1.98m—Since the pandemic started. I initially thought it was an error and held off posting it, but it’s apparently correct. Https://t.co/E50EW54MR0 [Tweet]. @pkedrosky. https://twitter.com/pkedrosky/status/1402047355029917696
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