1,012 Matching Annotations
  1. Dec 2020
    1. In 1971 Gánti tackled the problem head-on in a new book, Az Élet Princípiuma, or The Principles of Life. Published only in Hungarian, this book contained the first version of his chemoton model, which described what he saw as the fundamental unit of life. However, this early model of the organism was incomplete, and it would take him another three years to publish what is now regarded as the definitive version—again only in Hungarian, in a paper that is not available online.
    2. In 1966 he published a book on molecular biology called Forradalom az Élet Kutatásában, or Revolution in Life Research, a dominant university textbook for years—partly because few others were available. The book asked whether science understood how life was organized, and concluded that it did not.
    3. That’s because he devised a model of the simplest possible living organism, which he called the chemoton, that points to an exciting explanation for how life on Earth began.

      Tibor Gánti

  2. Nov 2020
    1. Since I closed down the Dish, my bloggy website, five years ago, after 15 years of daily blogging, I have not missed the insane work hours that all but broke my health.
    1. but know I know what I don't want to do. I definitely know I want to be an Engineer now, and it makes it more clear that I should start my own business.
    1. anything that makes you lighter helps create the balance which keeps you going.

      "In order to balance I never left anything pending on my to-do-list for tomorrow. If I did, I worked on break shift from home post putting her off to sleep. This was possible because I could manage my office on laptop. To release the pressure points I tore papers, took cold water bath in the middle of the night, laid on the floor in child pose." Monica Suri

  3. Oct 2020
    1. Work is where you spend the majority of your waking hours

      A week has 168 hours, if you sleep 56 hours a week, and work 40, and commute 10, you still get 62 hours if your wake time for something else. How you spend them is up to you.

    1. Lifelong learning: Formal, non‐formal and informal learning in the context of the use of problem‐solving skills in technology‐rich environments 

      Nygren, H., Nissinen, K., Hämäläinen, R., & Wever, B. (2019). Lifelong learning: Formal, non‐formal and informal learning in the context of the use of problem‐solving skills in technology‐rich environments. British Journal of Educational Technology, 50(4), 1759–1770. https://doi.org/10.1111/bjet.12807

      The evolving technological landscape in the digital era has a crucial influence on lifelong learning and the demand for problem‐solving skills. In this paper, we identify associations between formal, non‐formal and informal learning with sufficient problem‐solving skills in technology‐rich environments (TRE). We focus on adults' problem‐solving skills in TRE as a novel approach to investigate formal, non‐formal and informal learning based on data from the Programme for the International Assessment of Adult Competencies. This programme measured 16–64‐year‐old adults' proficiency in problem‐solving skills in TRE. The total sample size was 61 654 individuals from 13 European countries. Our results clearly indicate that the skill levels of more than 50% of adults aged 16–64 years old seem to be insufficient to cope effectively in TRE. The findings suggest that the learning ecologies of adults are a combination of formal, non‐formal and informal learning activities. The overall level of problem‐solving skills in TRE was higher among individuals who indicated that they have participated either formal or non‐formal learning activities, compared to those who have not. However, interestingly, the association between formal learning and problem‐solving skills in TRE was not major. Instead, our results clearly indicate that informal learning seems to be highly associated with sufficient problem‐solving skills in TRE. In practice, we outline those formal, non‐formal and informal learning activities that adults perform when applying the skills in TRE. By recognising these activities undertaken by sufficient problem solvers, we can promote lifelong learning skills. Our findings can also be used as a starting point for future studies on lifelong learning.

      https://search.ebscohost.com/login.aspx?direct=true&AuthType=shib&db=tfh&AN=138139297&site=eds-live&scope=site&custid=uphoenix

    1. they found that the glyoxylate and pyruvate reacted to make a range of compounds that included chemical analogues to all the intermediary products in the TCA cycle except for citric acid. Moreover, these products all formed in water within a single reaction vessel, at temperatures and pH conditions mild enough to be compatible with conditions on Earth.
    1. In the meantime, the classification of viruses remains unclear. Tupanviruses seem to be dependent on their hosts for very little, and other viruses, according to one preprint, even encode ribosomal proteins. “The gap between cellular organisms and viruses is starting to close,” Deeg said.

      Is there a graph of known viruses categoriezed by the machinery that they do or don't have? Can they be classified and sub-classified so that emergent patterns come forward thus allowing us to trace back their ancestry?

    1. Chetty is also using tax data to measure the long-term impacts of dozens of place-based interventions, such as enterprise zones, which use tax and other incentives to draw businesses into economically depressed areas.

      It wasn't this particular piece of text, but roughly at about here I had the thought that these communities could be looked at as life from an input /output perspective in relation to homeostasis. Essentially they're being slowly starved out and killed in a quietly moral yet amoral way. As a result entropy is slowly killing them and also causing problems for the society around them that blames the them for their own problems. Giving them some oxygen to breathe and thrive will fix so many of the problems.

    1. Where the provisioning trade predominated, black men worked as stock minders and herdsmen while black women labored as dairy maids as well as do- mestics of various kinds.

      Slaves in the North were living in better life than the Southern slaves.

  4. Sep 2020
    1. This study focuses on higher education instructors in the Global South, concentrating on those located in South America, Sub-Saharan Africa, and South and Southeast Asia. Based on a survey of 295 instructors at 28 higher education institutions (HEIs) in nine countries (Brazil, Chile, Colombia; Ghana, Kenya, South Africa; India, Indonesia, Malaysia), this research seeks to establish a baseline set of data for assessing OER use in these regions while attending to how such activity is differentiated across continental areas and associated countries. This is done by examining which variables – such as gender, age, technological access, digital literacy, etc. – seem to influence OER use rates, thereby allowing us to gauge which are the most important for instructors in their respective contexts.The two research questions that drive this study are:1. What proportion of instructors in the Global South have ever used OER?2. Which variables may account for different OER usage rates between respondents in the Global South?

      Survey, assessment, data and research analysis of OER use and impact in the global south

    1. Part of the reason is there’s a slight lag. No matter how good your internet is, no matter how fast it is, it seems we have this millisecond—maybe a few milliseconds—delay. So the communication isn’t in real time, even though it seems like it is. Our brains subconsciously pick up on the fact that things aren’t quite right. And the fact that things are out of sync and we’re accustomed to them being in sync when it’s face-to-face communication, our brains try to look for ways to overcome that lack of synchrony. After a few calls a day, it starts to become exhausting.

      Does this mean, if I'm naturally slow to react even in real life, it'll be exhausting for the interlocutor?

  5. eclass.srv.ualberta.ca eclass.srv.ualberta.ca
    1. Tree of Life

      The 'Tree of Life' has been present throughout many cultures and religions across history. It has been known by many different names but the meaning is always a source of life or a creator. The ancient Egyptians, Christians, Myahs, and Assyrians all believed in this 'Tree of Life.'

    1. In a world where comfort is king, arduous physical activity provides a rare opportunity to practice suffering.

      This is actually a very good insight that can be applied to the spiritual life.

    1. You have everything that you need right here. I think that you are in charge of your attitude, which is the most important thing that you will ever have.

      I can only achieve what I can with what I have

  6. Aug 2020
    1. 07:20 And the reason is very simple. In life, you draw energy from so many sources you don t 07:28 even realize. You get energy from your parents, because you want to make them proud, 07:33 you get energy from your friends, because you want to be the best guy to hang out with, 07:39 you get energy from your kids, because you want to provide an amazing life for them.

      Having expectations to live up to and having the confidence that you will be able to

    2. That s when I learned another very important lesson; you don t always control your own 10:29 fate.

      Not only know what you cannot change, but expect things you cannot change to happen

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  7. Jul 2020
    1. Your coworkers being an important part of your day-to-day experience is unsurprising, and what I’ve found increasingly true is that your current coworkers also have an outsized influence on your career long after you’ve stopped working together.

      Bangun jaringan teman kerja yang kuat, seandainya udah ga kerja ditempat tersebut, kesempatan kerja bisa datang dari mereka.

      Cari teman kerja yang bisa menjadi rival, ngepush kemampuan diri sendiri ke ambang batas.

    2. Consequently, the best roles are only accessible if you’re already financially stable, whether it’s stability from an existing role that’s you can interview from, or from savings and investments that allow you to pause between roles to rest and explore.

      Dengan keamanan keuangan, kamu bisa memberi jeda dan memilih mana yang sesuai

    3. Financial security is a prerequisite to own your pace and learning.

      Keamanan keuangan adalah sebuah keuntungan.

    4. Each year identify one or two new things–things that you’re uncomfortable with–and do them! You’ll continue growing yourself, adding more and more pieces to your toolkit.

      Ketika kamu merasa tidak nyaman, artinya kamu sedang belajar

  8. Jun 2020
    1. it’s paramount that each person — regardless of being for or against the result — individually pledges support out loud in the meeting. “Go around the room and ask each one of them to support the decision one at a time,” he says. “Commitment meetings are really important, because when you pledge to support a decision in the presence of your peers, you're much more likely to support it.

      Damn. Not gonna lie this sounds a little bit culty

    2. think of the last time you were handed a decision that someone else made but for which you had to execute and usher to success. How did that feel? I’d guess it made you feel frustrated, powerless or disengaged. We want to avoid that. That’s why the decision maker is both accountable and responsible. It’s more fulfilling and empowering.

      Plus, if you're engaged with something, it makes it no longer a chore, and more of pleasure to do the work related to it.

    3. people understand the when, and the ‘why’ of the ‘when.’”

      This is so important. I hate being told (not) to do something without knowing why I'm (not) meant to do it. Transparency is key and a lack of it can lead to a lack of motivation for me. Adding meaning to deadlines.

    4. forward-thinking companies still gravitate to consensus as the way to make decisions. It turns out that for important, difficult choices, that approach is often ineffective and impractical.

      kind of like how big FOSS projects have a BDFL for ultimate decision-making

    1. Can strongly say that this is the case for myself aswell. Another detail that wfh proponents seem to forget.

    1. There are four types among those who sit before the sages: a sponge, a funnel, a strainer and a sieve.A sponge, soaks up everything; A funnel, takes in at one end and lets out at the other; A strainer, which lets out the wine and retains the lees; A sieve, which lets out the coarse meal and retains the choice flour.
    2. There are four kinds of temperments:Easy to become angry, and easy to be appeased: his gain disappears in his loss; Hard to become angry, and hard to be appeased: his loss disappears in his gain; Hard to become angry and easy to be appeased: a pious person; Easy to become angry and hard to be appeased: a wicked person.
    3. According to the labor is the reward
    1. Snyder-Mackler, N., Burger, J. R., Gaydosh, L., Belsky, D. W., Noppert, G. A., Campos, F. A., Bartolomucci, A., Yang, Y. C., Aiello, A. E., O’Rand, A., Harris, K. M., Shively, C. A., Alberts, S. C., & Tung, J. (2020). Social determinants of health and survival in humans and other animals. Science, 368(6493). https://doi.org/10.1126/science.aax9553

  9. May 2020
    1. (He was also hit by a car when he was eight and stabbed by a stranger in a bar fight while out with the actor Vince Vaughn in 2001. “I came close to death,” he says, casually reflecting on the latter incident. “That was probably the closest I've been, besides being hit by a bus and a car.”)
    1. When you ask yourselves a lot of why, you might be overwhelmed about those kind of questions, because this kind of question require a lot of time, context, and knowledge to be answered.

      Perlu membatasi ruang lingkup dari pertanyaan itu sendiri

    1. I make an effort to nurture relationships with people I care about. Be a good friend, good daughter, good human

      Yang bikin hidup lebih berarti ada mempunyai hubungan bermakna

  10. Apr 2020
    1. Salganik, M. J., Lundberg, I., Kindel, A. T., Ahearn, C. E., Al-Ghoneim, K., Almaatouq, A., Altschul, D. M., Brand, J. E., Carnegie, N. B., Compton, R. J., Datta, D., Davidson, T., Filippova, A., Gilroy, C., Goode, B. J., Jahani, E., Kashyap, R., Kirchner, A., McKay, S., … McLanahan, S. (2020). Measuring the predictability of life outcomes with a scientific mass collaboration. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1915006117

    1. General surgeons in communities without emergency neurosurgical coverage should have a working knowledge of burr hole placement in the event that emergent evacuation is required for a life-threatening epidural hematoma
    1. “If you could have done it on your own, you already would have done it.”

      Gotta be honest with yourself. If you haven't finished what needs to be finished, there's a reason for that.

      It could be you're no longer interested. If that's the case, wtf are you trying so hard for? Give it up. Don't waste your time doing something you don't wanna do.

      However, though, if it's something you're passionate about, and you're mad at yourself for having not finished it already, then there's passion in the tank. The work must be done because, if you don't, you'll die crying.

      So if you're still passionate about the project, and you're not getting the job done to completion, there's another reason for your faults...

      You're not gifted enough to perform whatever portion of the project you're struggling to complete.

      And that's fine! It's alright to suck! If people didn't suck at stuff, there'd be no reason to have so many different professions. Everyone would just leverage their god-like overall awesomeness, where there's nothing you can't do perfectly, and do everything yourself.

      But that's not the world we live in. Our world includes other people; people who live to deliver their unique solution, talents, advice, etc. to people like you.

      Life is best when there's harmony. Harmony is often found within; but, oftentimes, harmony can't be enjoyed without help from others.

      Note to self: Hire a developmental copyeditor!

  11. Mar 2020
    1. In addition to supporting Trinitas’s medical administration, staff, nurses, and patrons, Marrapodi has been supporting consumers around the world through the 3-D virtual reality program Second Life. Second Life ’s host site, Whole Brain Health within Second Life, aims to keep people over fifty-five mentally active. “People have this stereotype that senior citizens can’t handle a smart phone,” Marrapodi commented, but over 20,000 people have seen Marrapodi’s virtual displays. She enjoyed receiving a thank-you email from a research scientist in Singapore for her efforts educating consumers on the coronavirus.

      Didn't know it was still up and running...

  12. Feb 2020
    1. Half-life22.04 hours

      It appears they are calculating based on total T3 rather than added T3. Assuming that the conversion of T4 to T3 remains constant, the half life of the liothyronine dose towards baseline is less than 10 hours (I'd estimate 5-7 hours). Given that this is short compared to other studies, it is likely that the conversion was slowed by the high thyroid status.

  13. Dec 2019
    1. This article is both beautiful and sad. It's wonderful that Duff McDonald is able to have such a rich relationship with his daughter even though he is only able to see her 2 days every two weeks. At the same time having all extra communication be mediated and recorded by 3d parties is chilling.

  14. Nov 2019
    1. The article, "Keys to success: Self-directed learning,' authors Fellows, Culver, and Beston discuss the components of Grow's self-directed learning (SDL) model. Learners and instructors fit into a matrix which can be used to determine optimal instructional strategies to meet the readiness of the learner. The authors discuss how SDL is implemented in multiple institutions for higher education. Instructional methods are shared to address foundational SDL skills as well as issues that arose when learners were having difficulty transitioning from one stage of readiness to another. Overall, holistic learner skills were enhanced with SDL. Rating: 9/10

    1. Author Jeff Cobb features guest Celisa to discuss trends in the field of lifelong learning. The speakers note twelve existing trends such as MOOCs, micro-credentials, neuroscience, and self-directed learning. Both private and public sectors or contributing to existing and emerging trends. Life-long learning is transforming as services explore free and paid services to extend learning to more populations.

    1. Section 508 compliance is discussed to support instructors knowledge of section 508 and how to begin the process of ensuring instructional content is 508 compliant. Section 508 of the federal Rehabilitation Act governs access of media to all persons whether they have a disability or not. Including captions, audio description, and accessible video players are vital to compliance. Compliance with 508 is necessary given that data that illustrates the percent of employees that have need for accommodations to support their learning. This brief article seems highly related to Universal Design of Learning. Rating: 10/10

    1. This makes me think shrines to birth sites should also be possible, and would also mark the boundary between life and death.

  15. Oct 2019
    1. What is the good life? What is the good man? The good woman? What is the good society and what is my relation to it? What are my obligations to society? What is best for my children? What is justice? Truth? Virtue? What is my relation to nature, to death, to aging, to pain, to illness? How can I live a zestful, enjoyable, meaningful life? What is my responsibility to my brothers? Who are my brothers? What shall I be loyal to? What must I be ready to die for?—Abraham Maslow

      Please reflect and respond to the following questions: What is the good life to you? Who are your brothers (i.e., your people)? What should you be loyal to?

      I appreciate your honest reflections (in advance).

  16. Sep 2019
    1. students quite often reported choosing their major based on taking introductory courses with particularly dynamic professors.
    2. make the entire course relevant to students’ daily lives. All of the labs center around chemicals and materials that students interact with regularly. For instance, they evaluate bottled water versus tap water, test both for pH, conductivity, and taste, and then debate why so many people choose bottled over tap