2,865 Matching Annotations
  1. Oct 2021
    1. Wenzel, J., Lampe, J., Müller-Fielitz, H., Schuster, R., Zille, M., Müller, K., Krohn, M., Körbelin, J., Zhang, L., Özorhan, Ü., Neve, V., Wagner, J. U. G., Bojkova, D., Shumliakivska, M., Jiang, Y., Fähnrich, A., Ott, F., Sencio, V., Robil, C., … Schwaninger, M. (2021). The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells. Nature Neuroscience, 1–12. https://doi.org/10.1038/s41593-021-00926-1

    1. This love for the ocean grew over the years, so much so that when she saw photographs by Canadian artist Benjamin Von Wong – showing a mermaid swimming in an ocean of plastic bottles – it impacted her deeply.
    1. An organization of designers collectively advocating for the ethical practice of design and for the bargaining power of employees, freelancers, and educators against the commoditization of design by corporate and capitalist value extraction that is actively undermining the flourishing of humans for the sake of monopolizing social communication through advertising and marketing and the accumulation of profits for the benefit of a select few at the top of the corporate hierarchies.

      I am curious to read The Ministry for the Future by Kim Stanley Robinson as recommended by Raphaelle Moatti in the Design Science Studio coheART2.

    1. If I could get policymakers, and citizens, everywhere to read just one book this year, it would be Kim Stanley Robinson’s The Ministry for the Future.

      Quoted on the Amazon product page for the book, The Ministry for the Future by Kim Stanley Robinson.

      The book was recommended by Raphaelle Moatti in the Design Science Studio coheART2.

    1. In ecology, edge effects are changes in population or community structures that occur at the boundary of two or more habitats.[1] Areas with small habitat fragments exhibit especially pronounced edge effects that may extend throughout the range. As the edge effects increase, the boundary habitat allows for greater biodiversity.

      Edge Effects

      It was in the Design Science Studio that I learned about edge effects.

      Yesterday, I was thinking about how my life embodies the concept of edge effects. That same day, a book was delivered to our door, Design for the Real World by Victor Papanek.

      Today, I was reading these words:

      Design for the Real World

      Design for Survival and Survival through Design: A Summation

      Integrated, comprehensive, anticipatory design is the act of planning and shaping carried on across the various disciplines, an act continuously carried on at interfaces between them.

      Victor Papanek goes on to say:

      It is at the border of different techniques or disciplines that most new discoveries are made and most action is inaugurated. It is when two differing areas of knowledge are brought into contact with one another that… a new science may come into being.

      (Page 323)


      Exiles and Emigrés

      The Bauhaus spread its ideas because it existed at the boundaries, the avant-garde, the edges of what was thought to be possible, especially as a socialist utopian idea found its way to a capitalist industrial-military complex, where the concept of modernism was co-opted and colonized by globalizing economic forces beyond the control of the individual. Design was the virus that propagated around the world through the vehicle of corporate globalization.

      That same design ethic is infecting corporations with a conscience, with empathy, with a process that begins with listening to people. Design is the virus that can spread the values of unconditional love throughout the body of neoliberal capitalism.

  2. www.programmableweb.com www.programmableweb.com
    1. Hypothesis REST API

      The Hypothesis API integrates annotations into web services. Available to send HTTP requests and JSON responses, it aims to be useful for researchers, scientists, and educators.

    1. Timothy Caulfield on Twitter: “Will you fall into the conspiracy theory rabbit hole? Https://t.co/8mLQqSBnqb by @databyler @codingyan Good breakdown on some of the social forces (like ideology) that drive conspiracy theories. Despite the fact I study topic, still amazed how many believe this stuff. Https://t.co/L1T0cpy9kB” / Twitter. (n.d.). Retrieved October 8, 2021, from https://twitter.com/CaulfieldTim/status/1445794723101175818

    1. “ I got validation as an artist, designer, writer, event organizer, leader, friend, and human being with influence, capacity, and agency by providing opportunities, permission, and encouragement to try everything.”— Anonymous

      Where my testimonial is featured on the Program page for the Design Science Studio, but attributed to Anonymous.

      This made me laugh. Actually, I prefer being anonymous.

      Or, maybe it is recognizing my limitations. Walter Gropius recognized his own limitations and turned that into an ability to connect with people who filled in the gaps in his capabilities. As an architect, his role was to gather people to fulfill a vision that was far beyond what he could accomplish on his own.

      The Hidden History of the Geodesic Dome - Part 3: The Teamwork of Walter Gropius

    2. “ The greatest benefit by far was to discover we are not alone. That there is a method to this madness”— Stephen Bau, Evolutionary

      Where my testimonial is featured on the Program page for the Design Science Studio.

    1. In Paris last June, at an assembly for architectural students held in conjunction with the International Union of Architects’ Eighth Biennial World Congress, the students adopted a proposal by Fuller that the years from 1965 to 1975 be designated as a World Design Science Decade.

      This New Yorker Magazine article from December 31, 1965 notes the adoption of the proposal for a World Design Science Decade from 1965 to 1975.

  3. Sep 2021
    1. Nicholas Carr explores cognitive science and media theory to understand how technology is change our brains through neuroplasticity.

      Ezra Klein was in conversation with Richard Powers regarding his recent book, Bewilderment, exploring the way technology changes us by changing our environment. The medium is the message.

    1. We are all designers

      A design brief for a project to reimagine our social architecture. The Design Science Studio is the new Bauhaus, the community, the builders collective who are building a world that works for 100% of life. The Stop Reset Go is the project that is exploring how we imagine, design, and build the kind of world that we want to live in. How do we empower humanity to be the designers who can engage in a process of bottom-up whole system change?

    1. “Andrew Harvey is Founder and Director of The Institute for Sacred Activism, an international organization focused on inviting concerned people to take up the challenge of our contemporary global crises by becoming inspired, effective, and practical agents of institutional and systemic change, in order to create peace and sustainability.”

    1. The effects of spiritual practices are now being investigated scientifically as never before, and many studies have shown that religious and spiritual practices generally make people happier and healthier.
    1. His questioning of the scientific orthodoxy was the expression of a rare and maverick intelligence. He shows us that the nature of reality is infinite and believed in a “hidden” regime of reality – the Quantum Potential – that underlies all of creation and which will remain beyond scientific endeavor, an idea echoed by many mystical traditions.

      “We are all participants and observers in the emergence of a reality…the Observer is the Observed. Bohm shows us that we are all co-producers of a possible future in which personal and global transformation is possible.”

    1. We are exploring how we imagine, design, and build the future together.

      Builders Collective

      So, they put together a team of individuals who could collectively imagine the possibilities of building the kind of world where they could all live together in peace. They made a simple declaration:

      We are exploring how we imagine, design, and build the future together.

    1. SuzeeB🙂. (2021, September 14). Dear vaccinated, We did not take your freedom. The government did. We are not holding your freedoms to ransom. The government is. If we are a danger to you, then your vaccine doesn’t work. If it does, then you should already be free. The government has lied to you. [Tweet]. @NatalieSuB. https://twitter.com/NatalieSuB/status/1437835320628809733

    1. Ben Collins on Twitter: “A quick thread: It’s hard to explain just how radicalized ivermectin and antivax Facebook groups have become in the last few weeks. They’re now telling people who get COVID to avoid the ICU and treat themselves, often by nebulizing hydrogen peroxide. So, how did we get here?” / Twitter. (n.d.). Retrieved September 26, 2021, from https://twitter.com/oneunderscore__/status/1441395300002848769?s=20

    1. Four Panel Discussions on Climate Solutions at Climate Week NYC 2021

      Maxi Cohen from the Design Science Studio invited us to the Climate Impact panel discussions.

      The video was live on Facebook Live.

    1. anti-vaccine movement

      it is also problematic how anti-science ideas are conflated with justified criticism about the development of this specific vaccine. it makes the anti-science camp look much more robust than it is

    1. The US writer Christie Aschwanden demonstrated how easily nutritional epidemiology can go awry in a piece on the website FiveThirtyEight in 2016. She ran a survey of the site’s readers, asking them questions about their diets and a range of personal attributes, such as whether they were smokers or if they believed the movie Crash deserved to win a best-picture Oscar. One association she turned up was that people who are atheists tend to trim the fat from their meat.

      Nice example of correlation-is-not-causation on foods.

    1. Scott Sampson has argued that we should subjectify nature rather than objectifying it. People are a part of nature and integral to it. We are not separate from it and we are assuredly not above it.

      Can the injection of multi-disciplinary research and areas like big history help us to see the bigger picture? How have indigenous and oral cultures managed to do so much better than us at this? Is it the way we've done science in the past? Is it our political structures?

    1. Liu, W., Russell, R. M., Bibollet-Ruche, F., Skelly, A. N., Sherrill-Mix, S., Freeman, D. A., Stoltz, R., Lindemuth, E., Lee, F.-H., Sterrett, S., Bar, K. J., Erdmann, N., Gouma, S., Hensley, S. E., Ketas, T., Cupo, A., Cruz Portillo, V. M., Moore, J. P., Bieniasz, P. D., … Hahn, B. H. (2021). Predictors of Nonseroconversion after SARS-CoV-2 Infection. Emerging Infectious Diseases, 27(9), 2454–2458. https://doi.org/10.3201/eid2709.211042

  4. Aug 2021
    1. Basic research leading to scientific discovery is thus a public good. It will benefit all. But, because the private incentive to pay for basic research is therefore attenuated, the private sector as a matter of economic self-interest is likely to underinvest in it. Therefore, if the full social potential of this public good is to be realized, the investment must come from government.

      Sounds argument against neoliberal views for privitized R&D.

    2. investments in basic research are variously estimated as ultimately returning between 20% and 60% per year (13).

      Science delivers x20 the typicall ROI!

    3. Their finding was that at most half of the historical growth could be explained by known factors. The unexplained part, sometimes estimated as large as 85%, was termed the Solow residual

      Definition of the "Solow residual".

    1. Pham, Q. T., Le, X. T. T., Phan, T. C., Nguyen, Q. N., Ta, N. K. T., Nguyen, A. N., Nguyen, T. T., Nguyen, Q. T., Le, H. T., Luong, A. M., Koh, D., Hoang, M. T., Pham, H. Q., Vu, L. G., Nguyen, T. H., Tran, B. X., Latkin, C. A., Ho, C. S. H., & Ho, R. C. M. (2021). Impacts of COVID-19 on the Life and Work of Healthcare Workers During the Nationwide Partial Lockdown in Vietnam. Frontiers in Psychology, 12, 563193. https://doi.org/10.3389/fpsyg.2021.563193

    1. Kai Kupferschmidt on Twitter: “One of the most important things I was looking for in reporting on #SARSCoV2 evolution was a way of making sense of all the virus variants, putting them in some framework. And one of the most useful things I found for that is this antigenic map. It’s worth explaining a bit: Https://t.co/miO8Kh9w9e” / Twitter. (n.d.). Retrieved August 22, 2021, from https://twitter.com/kakape/status/1428650961652916230?s=20

    1. by the eighteenth century, suchchapters were being expanded into sizeable books that functioned primarily as natural historybibliographies in their own right. An early example of this practice was Johann JakobScheuchzer’s Bibliotheca scriptorium(1716).
    1. ReconfigBehSci on Twitter: “@ToddHorowitz3 ok, but I would have hoped that in an ideal public communication medium for science, people had megaphones that were commensurate with their skills and expertise, if there was variation among platform members at all. And I’d hope that users were calibrated re own expertise” / Twitter. (n.d.). Retrieved August 10, 2021, from https://twitter.com/SciBeh/status/1423710934925598725

    1. Everett, J. A. C., Colombatto, C., Awad, E., Boggio, P., Bos, B., Brady, W. J., Chawla, M., Chituc, V., Chung, D., Drupp, M., Goel, S., Grosskopf, B., Hjorth, F., Ji, A., Kealoha, C., Kim, J. S., Lin, Y., Ma, Y., Maréchal, M. A., … Crockett, M. (2021). Moral dilemmas and trust in leaders during a global health crisis [Preprint]. PsyArXiv. https://doi.org/10.31234/osf.io/mzswb

    1. Tammy Duckworth. (2021, July 22). Please—Listen to the experts. 97% of those hospitalized from COVID-19 are unvaccinated. Over 99% of those dying from COVID-19 are unvaccinated. This is not political. It is not a hoax. I got my vaccine right away and you should too. [Tweet]. @TammyDuckworth. https://twitter.com/TammyDuckworth/status/1418258402623557634

  5. Jul 2021
    1. I would rather see the scientists and the healers and the artists depicted in a heroic light.

      Why are so many villains in comic books depicted as scientists? Has this harmed the American psyche? Encouraged an anti-science temperament?

      Observation sparked, in part, to episode of Young Sheldon, Season 1 about Sheldon's eating issues.

    1. Aristotle already thought the argument to be deceiving. He ridicules it by saying that according to the same kind of argument a hair, which was subject to an even pulling power from opposing sides, would not break, and that a man, being just as hungry as thirsty, placed in between food and drink, must necessarily remain where he is and starve. To him it was the wrong argument for the right proposition. Absolute propositions concerning the non-existence of things are always in danger of becoming falsified on closer investigation. They contain a kind of subjective aspect: “as far as I know.”

      Aristotle came up with some solid counter examples against using the principle of sufficient reason and showed how they could be falsified.

      What is the flaw in logic that would cause it to fail? Are there situations in which it could be used reliably? Ones in which it can't?