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AssayResult: 5.2

AssayResultAssertion: Normal

StandardErrorMean: 0.33

HGVS: NM_024675.3:c.1732A>G p.(Ser578Gly)

AssayResult: 97.77

AssayResultAssertion: Not reported

PValue: > 0.9999

Comment: Exact values reported in Table S3.

HGVS: NM_024675.3:c.3049G>A p.(Ala1017Thr)

Virological. ‘Recombinant SARS-CoV-2 Genomes Involving Lineage B.1.1.7 in the UK - SARS-CoV-2 Coronavirus / SARS-CoV-2 Molecular Evolution’, 17 March 2021. https://virological.org/t/recombinant-sars-cov-2-genomes-involving-lineage-b-1-1-7-in-the-uk/658.

Pimenta, Dominic, Christian Yates, Christina Pagel, and Deepti Gurdasani. ‘Delaying the Second Dose of Covid-19 Vaccines’. BMJ 372 (18 March 2021): n710. https://doi.org/10.1136/bmj.n710.

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AssayResult: 78.2

AssayResultAssertion: Not reported

ReplicateCount: 2

StandardErrorMean: 7.31

Comment: Exact values reported in “Source Data” file.

AssayResult: 87.35

AssayResultAssertion: Not reported

ReplicateCount: 2

StandardDeviation: 11.94

StandardErrorMean: 8.44

Comment: Exact values reported in “Source Data” file.

HGVS: NM_024675.3:c.2117C>T p.(T706I)

AssayResult: 120.5

AssayResultAssertion: Normal

ReplicateCount: 41

StandardErrorMean: 10.5

Comment: This variant had normal function (75-125% of wildtype peak current, <1% late current, no large perturbations to other parameters). These in vitro features are consistent with non-disease causing variants. (Personal communication: A. Glazer)

HGVS: NM_198056.2:c.2317C>T p.(Pro773Ser)

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